3AY5A

Crystal structure of hhm (human homologue of murine maternal id-like molecule)
Total Genus 122
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
122
sequence length
347
structure length
298
Chain Sequence
LASPLEQLRHLAEELRLLLPRVRVGEATEEFNREMFWRRLNEAAVTVSREATTLTIVFSQLPLPSPQETQKFCEQVHAAIKAFIAVYYLLPKDQGITLRKLVRGATLDIVDGMAQLMEVLSVNSVWVACQQMPQIPRDNKAAALLMLTKNVDFVKDAHEEMEQAVEESDPQDLYWSEDDQELIIPCLALVRASKACLKKIRMLVAENGKKDQVAQLDDIVDISDEISPSVDDLALSIYPPMSHLTVRINSAKLVSVLKKALEITKASHVTPSWIPLLINAIDHCMNRIKELTQSELEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of a dominant-negative helix-loop-helix transcriptional regulator suggests mechanisms of autoinhibition.
pubmed doi rcsb
molecule tags Cell cycle
source organism Homo sapiens
molecule keywords Cyclin-D1-binding protein 1
total genus 122
structure length 298
sequence length 347
ec nomenclature
pdb deposition date 2011-04-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF13324 GCIP Grap2 and cyclin-D-interacting
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1410.10 Mainly Alpha Up-down Bundle I/LWEQ domain I/LWEQ domain 3ay5A02
1.20.1420.10 Mainly Alpha Up-down Bundle A middle domain of Talin 1 Talin, central domain 3ay5A01
4F7GB 3AY5A 4W8PA 3FYQA 1R0DA 3DYJA 2KBBA 2L10A 2JSWA 1SJ7A 2KVPA 2L7NA 5FZTA 2X0CA 2KGXA 1SJ8A
chains in the Genus database with same CATH superfamily
5HYAA 3M1CA 3FYQA 5HXEA 2KBBA 2LQUA 3AT7A 2L10A 2JSWA 2MTCA 2X0CA 3PHF1 2KGXA 5T1DA 3WSCA 4ONRA 3AY5A 3PF0A 4W8PA 5JDLA 5JDFA 3DYJA 5JDHA 3WURA 3V5SA 5HXCA 1SJ8A 5HXSA 4ECGA 5HWYA 4F7GB 5JDMA 5JDQA 5JDNA 5HXHA 3V5UA 2KVPA 5HWXA 5HXRA 4BGOA 1R0DA 2XQYA 2L7NA 1SJ7A 5FZTA 3VJZA 5JDGA
chains in the Genus database with same CATH topology
4F7GB 3AY5A 4W8PA 3FYQA 1R0DA 3DYJA 2KBBA 2L10A 2JSWA 1SJ7A 2KVPA 2L7NA 5FZTA 2X0CA 2KGXA 1SJ8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4F7G B;  3AY5 A;  4W8P A;  3FYQ A;  1R0D A;  3DYJ A;  2KBB A;  2L10 A;  2JSW A;  1SJ7 A;  2KVP A;  2L7N A;  5FZT A;  2X0C A;  2KGX A;  1SJ8 A; 
#chains in the Genus database with same CATH topology
 5HYA A;  3M1C A;  3FYQ A;  5HXE A;  2KBB A;  2LQU A;  3AT7 A;  2L10 A;  2JSW A;  2MTC A;  2X0C A;  3PHF 1;  2KGX A;  5T1D A;  3WSC A;  4ONR A;  3AY5 A;  3PF0 A;  4W8P A;  5JDL A;  5JDF A;  3DYJ A;  5JDH A;  3WUR A;  3V5S A;  5HXC A;  1SJ8 A;  5HXS A;  4ECG A;  5HWY A;  4F7G B;  5JDM A;  5JDQ A;  5JDN A;  5HXH A;  3V5U A;  2KVP A;  5HWX A;  5HXR A;  4BGO A;  1R0D A;  2XQY A;  2L7N A;  1SJ7 A;  5FZT A;  3VJZ A;  5JDG A; 
#chains in the Genus database with same CATH homology
 4F7G B;  3AY5 A;  4W8P A;  3FYQ A;  1R0D A;  3DYJ A;  2KBB A;  2L10 A;  2JSW A;  1SJ7 A;  2KVP A;  2L7N A;  5FZT A;  2X0C A;  2KGX A;  1SJ8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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