3B0AB

Crystal structure of the mouse hoil1-l-nzf in complex with linear di-ubiquitin
Total Genus 10
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
57
structure length
57
Chain Sequence
MPVGWQCPGCTFINKPTRPGCEMCCRARPETYQIPASYQPDEEERARLAGEEEALRQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Specific recognition of linear ubiquitin chains by the Npl4 zinc finger (NZF) domain of the HOIL-1L subunit of the linear ubiquitin chain assembly complex
pubmed doi rcsb
molecule tags Signaling protein/metal binding protein
source organism Homo sapiens
molecule keywords Polyubiquitin-C
total genus 10
structure length 57
sequence length 57
chains with identical sequence E
ec nomenclature ec 2.3.2.31: RBR-type E3 ubiquitin transferase.
pdb deposition date 2011-06-07
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.140 Mainly Beta Single Sheet Rubrerythrin, domain 2 Rubrerythrin, domain 2 3b0aB00
4XXBB 2PPTA 3P2AA 2C6BA 2C6AA 3B0AB 2J9UB 3B08B
chains in the Genus database with same CATH superfamily
3HOUL 2PSMC 2RFKB 4JAGA 4RXNA 4A3EL 4V196 4A3LL 4POGA 2A68D 2E2HL 2PVXA 2CKCA 1IROA 2APOB 2M4YA 4Y52L 1PFVA 2ERSA 2NVYL 1S2ZA 4JADA 1RB9A 3H0GL 5MFPA 3SS2A 2PPTA 1YUXA 4A3FL 2KKDA 1PFWA 2XJQA 1QYBA 3LPEB 1BQ8A 1NNQA 3PO2L 3LWQB 3GTJL 5MLC3 3VPBE 2XJTA 5IYBL 1PZXA 1IU6A 3HKZP 3HOWL 4BBRL 4GS7D 3WWLA 3H9CA 4BY1L 4AR6A 5C44L 8RXNA 1F4LA 4UY81 4BBSL 4WFN1 4AI0A 3PKJA 2XJUA 5MFZA 1T9QA 1C09A 4C3JL 5GAGc 2B63L 3HJWB 1LKPA 2XJVA 2M6PA 1DVBA 1LTLA 4AYBP 3FKIL 1VZIA 5GAEc 1RDGA 5FJ8L 3GTGL 2O5JD 1WJVA 2M6OA 3S14L 4A3KL 3CQZL 2JA6L 5IYCL 2ERJA 5EIOC 1B2OA 3S15L 5DM71 4A3JL 1I3QL 1VCXA 3S1ML 1R9TL 1YK4A 1IRNA 5AI3A 2JI2A 4AR4A 2A6HD 4C2M1 2XJRA 4LHLA 3M3YL 1CAAA 3I4ML 5IP7L 4X6AL 5IP9L 4TPUA 1JYBA 3GTPL 3KYUA 4ZN1B 1Z92B 6RXNA 3RZ6A 5M5XL 5IYDL 4JAFA 3RZTA 2PYAA 4QIWP 2KN9A 1SMWA 1I6HL 5M3FL 2GMGA 3B08B 2M4VA 4XXBB 2WB1P 4E6YA 1R0IA 2JI1A 1OWBA 5M3ML 2YU9L 1K83L 1P7PA 4A3ML 2AQCA 2L0ZA 1YK5A 3HJYB 3PZAA 3LWRB 1LKMA 2VL6A 1IU5A 3J7Z1 3J7Y1 1VZGA 2V3BB 3PL5A 3HOVL 3MSUA 4A3CL 1I50L 1R0GA 1Y1WL 1R0FA 3GTOL 2NVXL 2MS3A 1T9OA 5JVG1 4AR3A 1B2JA 4A3GL 4BXXL 2B5ID 3LWVB 3I4NL 3HAXC 5H1Sc 2NVTL 3HOZL 2R92L 3B0AB 2XJPA 3NFPI 3FDJA 1IW7D 1R0JA 3HOYL 1NXEA 4XGHA 1SMMA 3S1RL 3H9BA 1FHMA 2LCQA 2NVQL 5AI2A 3ZG6A 2AUSB 5C4JL 5FLML 1SMUA 3RZDL 1E8JA 1TWGL 3PIO1 2J9UB 3MQKB 3A44A 1VZHA 4AHZA 3K35A 4A3DL 2H12A 1BQ9A 1Y1VL 3PWFA 3GTKL 2RDVA 2Z3RB 1OWCA 1LKOA 4G6BA 3RYGA 1TWFL 1QCVA 4AHWA 4C3IL 2XJSA 5C4XL 1S30A 3H99A 1RWDA 5M5WL 4A3IL 1R0HA 2JI3A 3RZOL 4JAEA 2BE5D 4ZN3B 5GADc 4K9FA 5MF6A 1NXGA 5K2ME 2JA7L 2C6BA 2R93L 4YWLA 3HOXL 1DX8A 5AN9H 5MGNA 4AI1A 1RYTA 3S2HL 2CR8A 3QVDA 1RYQA 2NYDA 5C3EL 1ODHA 4POFA 3S16L 1BRFA 3KYWA 2HVYC 3GTML 4U671 5EINC 1H7VA 2K2DA 1ZRPA 2PVEA 2C6AA 3IU3I 3P8BA 1WCML 1PFUA 3S1NL 1B71A 2E2JL 4Y7NL 3JR7A 3PKIA 2Z3QB 2QL0A 4C3HL 3KYYA 2E2IL 3S1QL 1T9PA 2Y0SP 4YWMA 7RXNA 3GTQL 4LHNA 2V0FA 5DM61 3LWPB 4A3BL 1QQTA 4AR5A 3H3VM 1BE7A 2CKAA 4AHYA 2EY4E 3QQCE 4ME3A 4AI3A 4AI2A 3GTLL 3LNLA 2PMZP 4BY7L 2JA8L 3S17L 1S24A 2VUML 1B13A 2A6ED 3S2DL 3PO3L 3PIP1 1CADA 2ZIXA 2DSXA 3WWNB 4B8CD 1YUZA 1PFYA 2HR5A 1BFYA 4AHXA 3KYXA 5RXNA 1TWCL 1TWHL 3P2AA 4A93L 1YV1A 3M4OL 3MPSA 2WAQP 3LWOB 2JA5L 3H97A 4TVMA 3K7AL 1TWAL 5JVH1 5GAHc 1RDVA 2R7ZL 1FHHA 1SFOL 3KYVA 2A69D 5IY0A 2AYJA 2V0EA 5M5YL
chains in the Genus database with same CATH topology
1WJVA 2M6OA 1R0JA 1H7VA 2K2DA 1ZRPA 2PSMC 1NXEA 4JAGA 4RXNA 4XGHA 2PVEA 4V196 2ERJA 1SMMA 4POGA 2C6AA 3IU3I 5EIOC 3P8BA 2A68D 2PVXA 1B2OA 1IROA 2CKCA 2M4YA 1FHMA 2LCQA 2ERSA 1B71A 3PKIA 5AI2A 5DM71 3ZG6A 1VCXA 1S2ZA 4JADA 1RB9A 4U671 1YK4A 2Z3QB 2QL0A 5MFPA 3KYYA 1IRNA 5AI3A 2JI2A 4AR4A 2A6HD 2PPTA 3SS2A 1SMUA 1YUXA 1E8JA 3PIO1 2J9UB 2XJRA 2KKDA 1CAAA 1T9PA 3A44A 3NFPI 4LHLA 4YWMA 1VZHA 2XJQA 1QYBA 4AHZA 7RXNA 3LPEB 1BQ8A 3K35A 2H12A 1BQ9A 1NNQA 4LHNA 3PWFA 2V0FA 5DM61 2RDVA 2Z3RB 5MLC3 3VPBE 2XJTA 4TPUA 1OWCA 1IU6A 1LKOA 4G6BA 3RYGA 4AHWA 1QCVA 1JYBA 4AR5A 2CKAA 1BE7A 4AHYA 4GS7D 3QQCE 3KYUA 2XJSA 4ME3A 4AI3A 4AI2A 3LNLA 1S30A 1Z92B 3WWLA 4ZN1B 3RZ6A 6RXNA 1RWDA 4AR6A 1R0HA 2JI3A 4JAFA 8RXNA 3RZTA 4JAEA 1S24A 2PYAA 1B13A 2A6ED 2KN9A 1SMWA 2BE5D 4UY81 4ZN3B 2GMGA 3B08B 5GADc 2M4VA 4XXBB 4K9FA 5MF6A 1NXGA 5K2ME 3PIP1 4E6YA 1CADA 2C6BA 1R0IA 2JI1A 2ZIXA 2DSXA 3WWNB 4B8CD 1OWBA 4YWLA 1YUZA 2HR5A 1DX8A 1BFYA 2L0ZA 5AN9H 1YK5A 4AHXA 3PZAA 4WFN1 5MGNA 1LKMA 2VL6A 3KYXA 4AI1A 4AI0A 1RYTA 3PKJA 5RXNA 2XJUA 5MFZA 1IU5A 3J7Z1 3J7Y1 1VZGA 1T9QA 2CR8A 3P2AA 1RYQA 2NYDA 3QVDA 1C09A 1YV1A 2V3BB 3MPSA 5GAGc 3MSUA 1ODHA 4POFA 1R0GA 1LKPA 2XJVA 1R0FA 1BRFA 2M6PA 1DVBA 4TVMA 2MS3A 1T9OA 5JVG1 1LTLA 4AR3A 1B2JA 5JVH1 5GAHc 2B5ID 1RDVA 1VZIA 3KYWA 5H1Sc 5GAEc 1FHHA 1RDGA 2O5JD 3KYVA 2A69D 5IY0A 3B0AB 2XJPA 2AYJA 2V0EA 1IW7D 5EINC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4XXB B;  2PPT A;  3P2A A;  2C6B A;  2C6A A;  3B0A B;  2J9U B;  3B08 B; 
#chains in the Genus database with same CATH topology
 3HOU L;  2PSM C;  2RFK B;  4JAG A;  4RXN A;  4A3E L;  4V19 6;  4A3L L;  4POG A;  2A68 D;  2E2H L;  2PVX A;  2CKC A;  1IRO A;  2APO B;  2M4Y A;  4Y52 L;  1PFV A;  2ERS A;  2NVY L;  1S2Z A;  4JAD A;  1RB9 A;  3H0G L;  5MFP A;  3SS2 A;  2PPT A;  1YUX A;  4A3F L;  2KKD A;  1PFW A;  2XJQ A;  1QYB A;  3LPE B;  1BQ8 A;  1NNQ A;  3PO2 L;  3LWQ B;  3GTJ L;  5MLC 3;  3VPB E;  2XJT A;  5IYB L;  1PZX A;  1IU6 A;  3HKZ P;  3HOW L;  4BBR L;  4GS7 D;  3WWL A;  3H9C A;  4BY1 L;  4AR6 A;  5C44 L;  8RXN A;  1F4L A;  4UY8 1;  4BBS L;  4WFN 1;  4AI0 A;  3PKJ A;  2XJU A;  5MFZ A;  1T9Q A;  1C09 A;  4C3J L;  5GAG c;  2B63 L;  3HJW B;  1LKP A;  2XJV A;  2M6P A;  1DVB A;  1LTL A;  4AYB P;  3FKI L;  1VZI A;  5GAE c;  1RDG A;  5FJ8 L;  3GTG L;  2O5J D;  1WJV A;  2M6O A;  3S14 L;  4A3K L;  3CQZ L;  2JA6 L;  5IYC L;  2ERJ A;  5EIO C;  1B2O A;  3S15 L;  5DM7 1;  4A3J L;  1I3Q L;  1VCX A;  3S1M L;  1R9T L;  1YK4 A;  1IRN A;  5AI3 A;  2JI2 A;  4AR4 A;  2A6H D;  4C2M 1;  2XJR A;  4LHL A;  3M3Y L;  1CAA A;  3I4M L;  5IP7 L;  4X6A L;  5IP9 L;  4TPU A;  1JYB A;  3GTP L;  3KYU A;  4ZN1 B;  1Z92 B;  6RXN A;  3RZ6 A;  5M5X L;  5IYD L;  4JAF A;  3RZT A;  2PYA A;  4QIW P;  2KN9 A;  1SMW A;  1I6H L;  5M3F L;  2GMG A;  3B08 B;  2M4V A;  4XXB B;  2WB1 P;  4E6Y A;  1R0I A;  2JI1 A;  1OWB A;  5M3M L;  2YU9 L;  1K83 L;  1P7P A;  4A3M L;  2AQC A;  2L0Z A;  1YK5 A;  3HJY B;  3PZA A;  3LWR B;  1LKM A;  2VL6 A;  1IU5 A;  3J7Z 1;  3J7Y 1;  1VZG A;  2V3B B;  3PL5 A;  3HOV L;  3MSU A;  4A3C L;  1I50 L;  1R0G A;  1Y1W L;  1R0F A;  3GTO L;  2NVX L;  2MS3 A;  1T9O A;  5JVG 1;  4AR3 A;  1B2J A;  4A3G L;  4BXX L;  2B5I D;  3LWV B;  3I4N L;  3HAX C;  5H1S c;  2NVT L;  3HOZ L;  2R92 L;  3B0A B;  2XJP A;  3NFP I;  3FDJ A;  1IW7 D;  1R0J A;  3HOY L;  1NXE A;  4XGH A;  1SMM A;  3S1R L;  3H9B A;  1FHM A;  2LCQ A;  2NVQ L;  5AI2 A;  3ZG6 A;  2AUS B;  5C4J L;  5FLM L;  1SMU A;  3RZD L;  1E8J A;  1TWG L;  3PIO 1;  2J9U B;  3MQK B;  3A44 A;  1VZH A;  4AHZ A;  3K35 A;  4A3D L;  2H12 A;  1BQ9 A;  1Y1V L;  3PWF A;  3GTK L;  2RDV A;  2Z3R B;  1OWC A;  1LKO A;  4G6B A;  3RYG A;  1TWF L;  1QCV A;  4AHW A;  4C3I L;  2XJS A;  5C4X L;  1S30 A;  3H99 A;  1RWD A;  5M5W L;  4A3I L;  1R0H A;  2JI3 A;  3RZO L;  4JAE A;  2BE5 D;  4ZN3 B;  5GAD c;  4K9F A;  5MF6 A;  1NXG A;  5K2M E;  2JA7 L;  2C6B A;  2R93 L;  4YWL A;  3HOX L;  1DX8 A;  5AN9 H;  5MGN A;  4AI1 A;  1RYT A;  3S2H L;  2CR8 A;  3QVD A;  1RYQ A;  2NYD A;  5C3E L;  1ODH A;  4POF A;  3S16 L;  1BRF A;  3KYW A;  2HVY C;  3GTM L;  4U67 1;  5EIN C;  1H7V A;  2K2D A;  1ZRP A;  2PVE A;  2C6A A;  3IU3 I;  3P8B A;  1WCM L;  1PFU A;  3S1N L;  1B71 A;  2E2J L;  4Y7N L;  3JR7 A;  3PKI A;  2Z3Q B;  2QL0 A;  4C3H L;  3KYY A;  2E2I L;  3S1Q L;  1T9P A;  2Y0S P;  4YWM A;  7RXN A;  3GTQ L;  4LHN A;  2V0F A;  5DM6 1;  3LWP B;  4A3B L;  1QQT A;  4AR5 A;  3H3V M;  1BE7 A;  2CKA A;  4AHY A;  2EY4 E;  3QQC E;  4ME3 A;  4AI3 A;  4AI2 A;  3GTL L;  3LNL A;  2PMZ P;  4BY7 L;  2JA8 L;  3S17 L;  1S24 A;  2VUM L;  1B13 A;  2A6E D;  3S2D L;  3PO3 L;  3PIP 1;  1CAD A;  2ZIX A;  2DSX A;  3WWN B;  4B8C D;  1YUZ A;  1PFY A;  2HR5 A;  1BFY A;  4AHX A;  3KYX A;  5RXN A;  1TWC L;  1TWH L;  3P2A A;  4A93 L;  1YV1 A;  3M4O L;  3MPS A;  2WAQ P;  3LWO B;  2JA5 L;  3H97 A;  4TVM A;  3K7A L;  1TWA L;  5JVH 1;  5GAH c;  1RDV A;  2R7Z L;  1FHH A;  1SFO L;  3KYV A;  2A69 D;  5IY0 A;  2AYJ A;  2V0E A;  5M5Y L; 
#chains in the Genus database with same CATH homology
 1WJV A;  2M6O A;  1R0J A;  1H7V A;  2K2D A;  1ZRP A;  2PSM C;  1NXE A;  4JAG A;  4RXN A;  4XGH A;  2PVE A;  4V19 6;  2ERJ A;  1SMM A;  4POG A;  2C6A A;  3IU3 I;  5EIO C;  3P8B A;  2A68 D;  2PVX A;  1B2O A;  1IRO A;  2CKC A;  2M4Y A;  1FHM A;  2LCQ A;  2ERS A;  1B71 A;  3PKI A;  5AI2 A;  5DM7 1;  3ZG6 A;  1VCX A;  1S2Z A;  4JAD A;  1RB9 A;  4U67 1;  1YK4 A;  2Z3Q B;  2QL0 A;  5MFP A;  3KYY A;  1IRN A;  5AI3 A;  2JI2 A;  4AR4 A;  2A6H D;  2PPT A;  3SS2 A;  1SMU A;  1YUX A;  1E8J A;  3PIO 1;  2J9U B;  2XJR A;  2KKD A;  1CAA A;  1T9P A;  3A44 A;  3NFP I;  4LHL A;  4YWM A;  1VZH A;  2XJQ A;  1QYB A;  4AHZ A;  7RXN A;  3LPE B;  1BQ8 A;  3K35 A;  2H12 A;  1BQ9 A;  1NNQ A;  4LHN A;  3PWF A;  2V0F A;  5DM6 1;  2RDV A;  2Z3R B;  5MLC 3;  3VPB E;  2XJT A;  4TPU A;  1OWC A;  1IU6 A;  1LKO A;  4G6B A;  3RYG A;  4AHW A;  1QCV A;  1JYB A;  4AR5 A;  2CKA A;  1BE7 A;  4AHY A;  4GS7 D;  3QQC E;  3KYU A;  2XJS A;  4ME3 A;  4AI3 A;  4AI2 A;  3LNL A;  1S30 A;  1Z92 B;  3WWL A;  4ZN1 B;  3RZ6 A;  6RXN A;  1RWD A;  4AR6 A;  1R0H A;  2JI3 A;  4JAF A;  8RXN A;  3RZT A;  4JAE A;  1S24 A;  2PYA A;  1B13 A;  2A6E D;  2KN9 A;  1SMW A;  2BE5 D;  4UY8 1;  4ZN3 B;  2GMG A;  3B08 B;  5GAD c;  2M4V A;  4XXB B;  4K9F A;  5MF6 A;  1NXG A;  5K2M E;  3PIP 1;  4E6Y A;  1CAD A;  2C6B A;  1R0I A;  2JI1 A;  2ZIX A;  2DSX A;  3WWN B;  4B8C D;  1OWB A;  4YWL A;  1YUZ A;  2HR5 A;  1DX8 A;  1BFY A;  2L0Z A;  5AN9 H;  1YK5 A;  4AHX A;  3PZA A;  4WFN 1;  5MGN A;  1LKM A;  2VL6 A;  3KYX A;  4AI1 A;  4AI0 A;  1RYT A;  3PKJ A;  5RXN A;  2XJU A;  5MFZ A;  1IU5 A;  3J7Z 1;  3J7Y 1;  1VZG A;  1T9Q A;  2CR8 A;  3P2A A;  1RYQ A;  2NYD A;  3QVD A;  1C09 A;  1YV1 A;  2V3B B;  3MPS A;  5GAG c;  3MSU A;  1ODH A;  4POF A;  1R0G A;  1LKP A;  2XJV A;  1R0F A;  1BRF A;  2M6P A;  1DVB A;  4TVM A;  2MS3 A;  1T9O A;  5JVG 1;  1LTL A;  4AR3 A;  1B2J A;  5JVH 1;  5GAH c;  2B5I D;  1RDV A;  1VZI A;  3KYW A;  5H1S c;  5GAE c;  1FHH A;  1RDG A;  2O5J D;  3KYV A;  2A69 D;  5IY0 A;  3B0A B;  2XJP A;  2AYJ A;  2V0E A;  1IW7 D;  5EIN C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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