3B7OA

Crystal structure of the human tyrosine phosphatase shp2 (ptpn11) with an accessible active site
Total Genus 96
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
96
sequence length
283
structure length
272
Chain Sequence
GFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Large-scale structural analysis of the classical human protein tyrosine phosphatome.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Hydrolase
molecule keywords Tyrosine-protein phosphatase non-receptor type 11
total genus 96
structure length 272
sequence length 283
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2007-10-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 3b7oA00
5K25A 5KA4A 1YWFA 2CMAA 2F6VA 5MMZB 1Q1MA 2F6ZA 2QDMA 1FQ1A 1GFYA 1XRIA 3V0EA 2HC2A 1C85A 4RKKA 1WCHA 3BM8A 1YTSA 2CFVA 4B04A 2I6MA 1XXPA 3EZZA 1JLNA 3V0DA 1OEUA 5KA1A 2PBNA 3V0IA 4OHDA 1BZCA 1MKPA 4KYRA 2H03A 3BLTA 1ZZWA 2BGDA 1PTYA 4GFVA 1P15A 3V0JA 3RGOA 2NZ6A 1L8KA 4QBWA 1AAXA 2CNHA 2QCJA 2BV5A 3M4UA 2HNPA 2P6XA 2VEWA 5KABA 2Y2FA 2B3OA 4QBEA 2HCMA 1ONZA 1OEOX 5IBMA 4QUNA 2QEPA 4RI4A 2QBRA 1NZ7A 3O5XA 4H34A 1XM2A 3EB1A 2NTAA 1GWZA 5BZZA 2FJNA 3O4TA 5KA3A 1C87A 4KYQA 5K24A 2GWOA 1YFOA 3S3EA 4WU3A 1QZ0A 3QCJA 2AHSA 2Y96A 3S3KA 3RGQA 3MOZA 2BZLA 4ZI4A 5EHRA 1Q6JA 1RXDA 4JMKA 2I3UA 2HB1A 4IKCA 1A5YA 1U24A 2FH7A 2NT2A 4QAPA 2HXPA 1RPMA 3OMHA 1L8GA 2IMGA 2I3RA 2OUDA 1OHEA 3S4EA 2CMBA 4QUMA 3N0AA 3AWFA 2HVLA 1D5RA 3F9BA 2PI7A 2B4OA 3D1HA 3D1OA 4OHEA 1NWLA 3GXHA 3SR9A 1ZCKA 4BPCA 5J8RA 3ZMQA 2ZMMA 5I6VA 3BLUA 3SMEA 4J51A 2I4GA 2QDPA 2CM3A 4NNDA 1C83A 4Z6BA 2DXPA 1PYNA 4TVVA 4RHGA 1KAVA 2BIJA 4PYHA 2NV5A 4GE2A 2H4VA 2I75A 3QCCA 2QDCA 3EMUA 1PTUA 2OOQA 3MOWA 2A3KA 3F41A 4ICZA 2I6OA 4GWFA 2J16B 1U25A 3ZV2A 4DGXA 1C86A 2PQ5A 5KACA 3AWEA 4MBBA 3EAXA 4R0SA 2B49A 3F81A 4RI5A 3QKPA 2C46A 4WTYA 4RDDA 4DGPA 1C88A 5BX1A 2YDUA 2QBQA 1I57A 1XXVA 2FJMA 2P4DA 4RH5A 1YPTA 2C7SA 1WAXA 1Q6MA 3OLRA 3D9CA 3ZMPA 1BZJA 1WRMA 1PH0A 4NX8A 2CNIA 3S4OA 4KI9A 5K9VA 3QCFA 2G6ZA 4HJPA 4YR8B 1G1GA 1G4WR 1T48A 2B07A 3A5JA 3MMJA 3F9AA 2Q05A 4YAAA 1OESA 3LJ8A 3D42A 2I42A 2GP0A 2B4SA 4JMJA 1YTWA 1EENA 2OC3A 4OHLA 3QCMA 2I4HA 2F6TA 2VEXA 2ESBA 1Q6PA 3PS5A 1LYVA 2CM7A 5KA7A 4R0TA 3ZM2A 1T4JA 5KA2A 3QCIA 1FPRA 3NMEA 5K23A 1KAKA 1BZHA 1PTVA 2PT0A 3ZM1A 4GRYA 2VEVA 2AZRA 4GE5A 1EEOA 5KA0A 2SHPA 3U96A 2F6YA 4Y14A 1Q6SA 2HC1A 3O4SA 5BZXA 1JF7A 2CNEA 5M43A 1M3GA 5HDEA 4D3RA 4I8NA 2J17A 2GJTA 4BJOA 2HNQA 2QBPA 1OEVA 2J16A 2I4EA 4HRFA 4GFUA 3QCGA 2A8BA 1NL9A 2B4PA 2I1YA 1LQFA 1ZCLA 3H2XA 1Q6NA 2B4UA 5KAAA 1X24A 4Y2EA 1OHCA 2Q47A 4D3QA 2VEUA 2I6JA 1Q6TA 1I9SA 1I9TA 1R6HA 1PXHA 2CNFA 1T49A 3QKQA 3D44A 1G1FA 1G4US 3V0FA 3QCEA 1C84A 3I80A 3S3FA 4R30A 2QCTA 3V0HA 3QCHA 1YGRA 1NWEA 3QCDA 4GRZA 2NT7A 4GS0A 5K22A 3I7ZA 2H4KA 2G59A 1G7GA 4JNBA 4NWGA 2PA5A 3A5KA 1LARA 1XBOA 3O4UA 1V3AA 1NO6A 2M3VA 3S3HA 4NWFA 2F71A 3D1QA 3ZM3A 3QCBA 4OHHA 1G7FA 2R0BA 5AWXA 1OETA 2QBSA 2OZ5A 2F46A 3CM3A 1PA1A 2ZN7A 2MBCA 5EHPA 5GTJA 2E0TA 4D3PA 3RO1A 2RF6A 1U26A 5LXQB 4QAHA 2F6WA 3BRHA 1ZC0A 4PVGA 4WU2A 4OHIA 4HJQA 3B7OA 2CM2A 2JJDA 2WGPA 5IBSA 3RZ2A 4S0GA 2PSZA 1YN9A 1SUGA 2F70A 5KADA 4WOHA 4NYHA 1ECVA 5K9WA 4ZRTA 5KA9A 2CMCA 3F99A 3V0GA 2CM8A 1PTTA 3O3LA 1VHRA 1YZ4A 1QXKA 2H04A 3ZM0A 1FPZA 1OHDA 2HY3A 3AWGA 4ZN5A 3QCLA 3GXGA 1PA9A 4AZ1A 2VEYA 2H02A 4ERCA 1J4XA 2H4GA 2NLKA 1YTNA 2CJZA 3QCNA 4RH9A 3CWEA 3EU0A 1ONYA 3I36A 1OEMX 2I6IA 1NNYA 2BGEA 2CNGA 2I6PA 4JBCA 5KA8A 2F6FA 2I5XA 1G1HA 3QCKA 4GE6A 4H1OA 5BUGA 1YGUA
chains in the Genus database with same CATH superfamily
5K25A 5KA4A 1E0DA 1YWFA 2GCAA 2CMAA 2F6VA 5MMZB 1Q1MA 1EEHA 2F6ZA 2QDMA 2XPCA 1FQ1A 1GFYA 1XRIA 3V0EA 2HC2A 1C85A 4RKKA 1WCHA 3BM8A 1YTSA 2CFVA 4B04A 2I6MA 1XXPA 3EZZA 1JLNA 3V0DA 1OEUA 5KA1A 2PBNA 3V0IA 4OHDA 1BZCA 1MKPA 4KYRA 2H03A 3BLTA 1ZZWA 2BGDA 1PTYA 4GFVA 1P15A 3V0JA 4CVMA 2AM1A 3RGOA 2NZ6A 1L8KA 1E8CA 4QBWA 1AAXA 2CNHA 2QCJA 2F00A 2BV5A 3QCZA 3M4UA 2HNPA 2P6XA 2VEWA 5KABA 2Y2FA 2B3OA 4QBEA 2HCMA 1ONZA 1OEOX 5IBMA 4QUNA 2QEPA 4ZIYA 4RI4A 2QBRA 1NZ7A 3O5XA 4H34A 1XM2A 3EB1A 2NTAA 1GWZA 5BZZA 2FJNA 3O4TA 5KA3A 1C87A 4KYQA 5K24A 2GWOA 1YFOA 3S3EA 4WU3A 1QZ0A 3QCJA 2AHSA 2Y96A 3S3KA 1O5ZA 3RGQA 3MOZA 2BZLA 4ZI4A 5EHRA 2Y66A 1Q6JA 1RXDA 2I3UA 4JMKA 2HB1A 4IKCA 1A5YA 1U24A 1P3DA 2FH7A 2NT2A 4QAPA 2HXPA 1RPMA 3OMHA 1L8GA 2IMGA 2I3RA 3LK7A 2OUDA 1OHEA 3S4EA 2CMBA 4HV4A 2VORA 4QUMA 3N0AA 3AWFA 2HVLA 1D5RA 2VTEA 3F9BA 2PI7A 2B4OA 2VOSA 3D1HA 4CVLA 3D1OA 4OHEA 1NWLA 3GXHA 3SR9A 1ZCKA 4BPCA 5J8RA 3ZMQA 2ZMMA 2UUPA 5I6VA 3BLUA 3SMEA 2VTDA 4J51A 2I4GA 2QDPA 2CM3A 1W78A 1C83A 4NNDA 4Z6BA 2DXPA 2WJPA 1PYNA 4TVVA 4RHGA 1KAVA 2BIJA 4PYHA 2NV5A 4GE2A 2H4VA 2I75A 3QCCA 2QDCA 3EMUA 1PTUA 2OOQA 3MOWA 2A3KA 3F41A 4ICZA 2I6OA 4GWFA 2J16B 1U25A 3ZV2A 4DGXA 3UAGA 1C86A 2PQ5A 5KACA 3AWEA 4MBBA 3EAXA 4R0SA 1JBWA 2B49A 3F81A 4RI5A 3QKPA 2C46A 4WTYA 4RDDA 4DGPA 1C88A 5BX1A 2YDUA 2QBQA 1I57A 1XXVA 2GC5A 2FJMA 2P4DA 4QDIA 1GQQA 4RH5A 1YPTA 2C7SA 1WAXA 1Q6MA 3OLRA 3D9CA 3ZMPA 3NRSA 1BZJA 1WRMA 1PH0A 4NX8A 2CNIA 3S4OA 4KI9A 5K9VA 3QCFA 2G6ZA 4HJPA 4YR8B 1G1GA 1P31A 1G4WR 1T48A 2B07A 3ZM5A 3A5JA 3MMJA 3F9AA 2Q05A 4YAAA 1OESA 3LJ8A 1GG4A 3D42A 2I42A 2GP0A 2B4SA 4JMJA 1YTWA 1EENA 4C12A 2OC3A 4OHLA 3QCMA 2I4HA 2F6TA 2VEXA 2ESBA 1Q6PA 3PS5A 1LYVA 2CM7A 5KA7A 4R0TA 3ZM2A 3ZM6A 1T4JA 3MVNA 5KA2A 3QCIA 1FPRA 3NMEA 5K23A 1KAKA 1BZHA 1PTVA 2PT0A 3ZM1A 4GRYA 2VEVA 2AZRA 4GE5A 1EEOA 5KA0A 2SHPA 3U96A 2F6YA 4Y14A 1Q6SA 2HC1A 3O4SA 5BZXA 1JF7A 2CNEA 5M43A 1M3GA 5HDEA 4D3RA 4I8NA 2J17A 2GJTA 4BJOA 2HNQA 4QF5A 2QBPA 1OEVA 2J16A 2I4EA 4HRFA 3PYZA 4GFUA 3QCGA 2A8BA 1NL9A 2B4PA 2I1YA 1LQFA 1ZCLA 3H2XA 1Q6NA 2B4UA 5KAAA 1X24A 4UAGA 4Y2EA 1OHCA 2Q47A 4D3QA 2VEUA 2I6JA 1Q6TA 1I9SA 1I9TA 1R6HA 3HN7A 1PXHA 2CNFA 1T49A 3QKQA 3D44A 1G1FA 1G4US 3V0FA 3QCEA 1C84A 3I80A 3S3FA 4R30A 2QCTA 3V0HA 3QCHA 1YGRA 1NWEA 3QCDA 4GRZA 2NT7A 4GS0A 2JFFA 5K22A 4C13A 3I7ZA 2AM2A 2H4KA 2G59A 1G7GA 2X5OA 4JNBA 4NWGA 2JFGA 2PA5A 3A5KA 1LARA 1XBOA 3O4UA 1V3AA 1NO6A 2M3VA 3S3HA 4NWFA 2F71A 3D1QA 1UAGA 3ZM3A 2GC6A 3QCBA 4OHHA 1G7FA 2R0BA 5AWXA 1OETA 2QBSA 2OZ5A 2F46A 3CM3A 1PA1A 2ZN7A 2MBCA 5EHPA 5GTJA 2E0TA 4D3PA 3RO1A 2RF6A 1U26A 5LXQB 4QAHA 2Y68A 2F6WA 3BRHA 1ZC0A 4BUCA 4PVGA 4WU2A 4OHIA 4HJQA 3B7OA 2CM2A 1FGSA 2JJDA 2WGPA 5IBSA 3RZ2A 4S0GA 2PSZA 5A5FA 1YN9A 1SUGA 2F70A 5KADA 3N2AA 4WOHA 4NYHA 1ECVA 5K9WA 4ZRTA 5KA9A 2GCBA 2CMCA 3F99A 1J6UA 3V0GA 2CM8A 1PTTA 3O3LA 1VHRA 1YZ4A 1QXKA 2H04A 3ZM0A 2UUOA 1FPZA 1OHDA 2HY3A 3AWGA 4ZN5A 3QCLA 2XJAA 3GXGA 1PA9A 4AZ1A 2VEYA 2H02A 4ERCA 1J4XA 2H4GA 2NLKA 1YTNA 2Y67A 2CJZA 3QCNA 4RH9A 2WTZA 3ZL8A 3CWEA 4CVKA 3EU0A 1GQYA 1ONYA 3I36A 2JFHA 1OEMX 2I6IA 2UAGA 1NNYA 5A5EA 2BGEA 4BUBA 2Y1OA 2CNGA 2I6PA 4JBCA 5KA8A 2F6FA 2I5XA 1G1HA 3QCKA 4GE6A 4H1OA 1W7KA 5BUGA 1JBVA 1YGUA
chains in the Genus database with same CATH topology
5K25A 5KA4A 1YWFA 2CMAA 2F6VA 5MMZB 1Q1MA 2F6ZA 2QDMA 1FQ1A 1GFYA 1XRIA 3V0EA 2HC2A 1C85A 4RKKA 1WCHA 3BM8A 1YTSA 2CFVA 4B04A 2I6MA 1XXPA 3EZZA 1JLNA 3V0DA 1OEUA 5KA1A 2PBNA 3V0IA 4OHDA 1BZCA 1MKPA 4KYRA 2H03A 3BLTA 1ZZWA 2BGDA 1PTYA 4GFVA 1P15A 3V0JA 3RGOA 2NZ6A 1L8KA 4QBWA 1AAXA 2CNHA 2QCJA 2BV5A 3M4UA 2HNPA 2P6XA 2VEWA 5KABA 2Y2FA 2B3OA 4QBEA 2HCMA 1ONZA 1OEOX 5IBMA 4QUNA 2QEPA 4RI4A 2QBRA 1NZ7A 3O5XA 4H34A 1XM2A 3EB1A 2NTAA 1GWZA 5BZZA 2FJNA 3O4TA 5KA3A 1C87A 4KYQA 5K24A 2GWOA 1YFOA 3S3EA 4WU3A 1QZ0A 3QCJA 2AHSA 2Y96A 3S3KA 3RGQA 3MOZA 2BZLA 4ZI4A 5EHRA 1Q6JA 1RXDA 4JMKA 2I3UA 2HB1A 4IKCA 1A5YA 1U24A 2FH7A 2NT2A 4QAPA 2HXPA 1RPMA 3OMHA 1L8GA 2IMGA 2I3RA 2OUDA 1OHEA 3S4EA 2CMBA 4QUMA 3N0AA 3AWFA 2HVLA 1D5RA 3F9BA 2PI7A 2B4OA 3D1HA 3D1OA 4OHEA 1NWLA 3GXHA 3SR9A 1ZCKA 4BPCA 5J8RA 3ZMQA 2ZMMA 5I6VA 3BLUA 3SMEA 4J51A 2I4GA 2QDPA 2CM3A 4NNDA 1C83A 4Z6BA 2DXPA 1PYNA 4TVVA 4RHGA 1KAVA 2BIJA 4PYHA 2NV5A 4GE2A 2H4VA 2I75A 3QCCA 2QDCA 3EMUA 1PTUA 2OOQA 3MOWA 2A3KA 3F41A 4ICZA 2I6OA 4GWFA 2J16B 1U25A 3ZV2A 4DGXA 1C86A 2PQ5A 5KACA 3AWEA 4MBBA 3EAXA 4R0SA 2B49A 3F81A 4RI5A 3QKPA 2C46A 4WTYA 4RDDA 4DGPA 1C88A 5BX1A 2YDUA 2QBQA 1I57A 1XXVA 2FJMA 2P4DA 4RH5A 1YPTA 2C7SA 1WAXA 1Q6MA 3OLRA 3D9CA 3ZMPA 1BZJA 1WRMA 1PH0A 4NX8A 2CNIA 3S4OA 4KI9A 5K9VA 3QCFA 2G6ZA 4HJPA 4YR8B 1G1GA 1G4WR 1T48A 2B07A 3A5JA 3MMJA 3F9AA 2Q05A 4YAAA 1OESA 3LJ8A 3D42A 2I42A 2GP0A 2B4SA 4JMJA 1YTWA 1EENA 2OC3A 4OHLA 3QCMA 2I4HA 2F6TA 2VEXA 2ESBA 1Q6PA 3PS5A 1LYVA 2CM7A 5KA7A 4R0TA 3ZM2A 1T4JA 5KA2A 3QCIA 1FPRA 3NMEA 5K23A 1KAKA 1BZHA 1PTVA 2PT0A 3ZM1A 4GRYA 2VEVA 2AZRA 4GE5A 1EEOA 5KA0A 2SHPA 3U96A 2F6YA 4Y14A 1Q6SA 2HC1A 3O4SA 5BZXA 1JF7A 2CNEA 5M43A 1M3GA 5HDEA 4D3RA 4I8NA 2J17A 2GJTA 4BJOA 2HNQA 2QBPA 1OEVA 2J16A 2I4EA 4HRFA 4GFUA 3QCGA 2A8BA 1NL9A 2B4PA 2I1YA 1LQFA 1ZCLA 3H2XA 1Q6NA 2B4UA 5KAAA 1X24A 4Y2EA 1OHCA 2Q47A 4D3QA 2VEUA 2I6JA 1Q6TA 1I9SA 1I9TA 1R6HA 1PXHA 2CNFA 1T49A 3QKQA 3D44A 1G1FA 1G4US 3V0FA 3QCEA 1C84A 3I80A 3S3FA 4R30A 2QCTA 3V0HA 3QCHA 1YGRA 1NWEA 3QCDA 4GRZA 2NT7A 4GS0A 5K22A 3I7ZA 2H4KA 2G59A 1G7GA 4JNBA 4NWGA 2PA5A 3A5KA 1LARA 1XBOA 3O4UA 1V3AA 1NO6A 2M3VA 3S3HA 4NWFA 2F71A 3D1QA 3ZM3A 3QCBA 4OHHA 1G7FA 2R0BA 5AWXA 1OETA 2QBSA 2OZ5A 2F46A 3CM3A 1PA1A 2ZN7A 2MBCA 5EHPA 5GTJA 2E0TA 4D3PA 3RO1A 2RF6A 1U26A 5LXQB 4QAHA 2F6WA 3BRHA 1ZC0A 4PVGA 4WU2A 4OHIA 4HJQA 3B7OA 2CM2A 2JJDA 2WGPA 5IBSA 3RZ2A 4S0GA 2PSZA 1YN9A 1SUGA 2F70A 5KADA 4WOHA 4NYHA 1ECVA 5K9WA 4ZRTA 5KA9A 2CMCA 3F99A 3V0GA 2CM8A 1PTTA 3O3LA 1VHRA 1YZ4A 1QXKA 2H04A 3ZM0A 1FPZA 1OHDA 2HY3A 3AWGA 4ZN5A 3QCLA 3GXGA 1PA9A 4AZ1A 2VEYA 2H02A 4ERCA 1J4XA 2H4GA 2NLKA 1YTNA 2CJZA 3QCNA 4RH9A 3CWEA 3EU0A 1ONYA 3I36A 1OEMX 2I6IA 1NNYA 2BGEA 2CNGA 2I6PA 4JBCA 5KA8A 2F6FA 2I5XA 1G1HA 3QCKA 4GE6A 4H1OA 5BUGA 1YGUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5K25 A;  5KA4 A;  1YWF A;  2CMA A;  2F6V A;  5MMZ B;  1Q1M A;  2F6Z A;  2QDM A;  1FQ1 A;  1GFY A;  1XRI A;  3V0E A;  2HC2 A;  1C85 A;  4RKK A;  1WCH A;  3BM8 A;  1YTS A;  2CFV A;  4B04 A;  2I6M A;  1XXP A;  3EZZ A;  1JLN A;  3V0D A;  1OEU A;  5KA1 A;  2PBN A;  3V0I A;  4OHD A;  1BZC A;  1MKP A;  4KYR A;  2H03 A;  3BLT A;  1ZZW A;  2BGD A;  1PTY A;  4GFV A;  1P15 A;  3V0J A;  3RGO A;  2NZ6 A;  1L8K A;  4QBW A;  1AAX A;  2CNH A;  2QCJ A;  2BV5 A;  3M4U A;  2HNP A;  2P6X A;  2VEW A;  5KAB A;  2Y2F A;  2B3O A;  4QBE A;  2HCM A;  1ONZ A;  1OEO X;  5IBM A;  4QUN A;  2QEP A;  4RI4 A;  2QBR A;  1NZ7 A;  3O5X A;  4H34 A;  1XM2 A;  3EB1 A;  2NTA A;  1GWZ A;  5BZZ A;  2FJN A;  3O4T A;  5KA3 A;  1C87 A;  4KYQ A;  5K24 A;  2GWO A;  1YFO A;  3S3E A;  4WU3 A;  1QZ0 A;  3QCJ A;  2AHS A;  2Y96 A;  3S3K A;  3RGQ A;  3MOZ A;  2BZL A;  4ZI4 A;  5EHR A;  1Q6J A;  1RXD A;  4JMK A;  2I3U A;  2HB1 A;  4IKC A;  1A5Y A;  1U24 A;  2FH7 A;  2NT2 A;  4QAP A;  2HXP A;  1RPM A;  3OMH A;  1L8G A;  2IMG A;  2I3R A;  2OUD A;  1OHE A;  3S4E A;  2CMB A;  4QUM A;  3N0A A;  3AWF A;  2HVL A;  1D5R A;  3F9B A;  2PI7 A;  2B4O A;  3D1H A;  3D1O A;  4OHE A;  1NWL A;  3GXH A;  3SR9 A;  1ZCK A;  4BPC A;  5J8R A;  3ZMQ A;  2ZMM A;  5I6V A;  3BLU A;  3SME A;  4J51 A;  2I4G A;  2QDP A;  2CM3 A;  4NND A;  1C83 A;  4Z6B A;  2DXP A;  1PYN A;  4TVV A;  4RHG A;  1KAV A;  2BIJ A;  4PYH A;  2NV5 A;  4GE2 A;  2H4V A;  2I75 A;  3QCC A;  2QDC A;  3EMU A;  1PTU A;  2OOQ A;  3MOW A;  2A3K A;  3F41 A;  4ICZ A;  2I6O A;  4GWF A;  2J16 B;  1U25 A;  3ZV2 A;  4DGX A;  1C86 A;  2PQ5 A;  5KAC A;  3AWE A;  4MBB A;  3EAX A;  4R0S A;  2B49 A;  3F81 A;  4RI5 A;  3QKP A;  2C46 A;  4WTY A;  4RDD A;  4DGP A;  1C88 A;  5BX1 A;  2YDU A;  2QBQ A;  1I57 A;  1XXV A;  2FJM A;  2P4D A;  4RH5 A;  1YPT A;  2C7S A;  1WAX A;  1Q6M A;  3OLR A;  3D9C A;  3ZMP A;  1BZJ A;  1WRM A;  1PH0 A;  4NX8 A;  2CNI A;  3S4O A;  4KI9 A;  5K9V A;  3QCF A;  2G6Z A;  4HJP A;  4YR8 B;  1G1G A;  1G4W R;  1T48 A;  2B07 A;  3A5J A;  3MMJ A;  3F9A A;  2Q05 A;  4YAA A;  1OES A;  3LJ8 A;  3D42 A;  2I42 A;  2GP0 A;  2B4S A;  4JMJ A;  1YTW A;  1EEN A;  2OC3 A;  4OHL A;  3QCM A;  2I4H A;  2F6T A;  2VEX A;  2ESB A;  1Q6P A;  3PS5 A;  1LYV A;  2CM7 A;  5KA7 A;  4R0T A;  3ZM2 A;  1T4J A;  5KA2 A;  3QCI A;  1FPR A;  3NME A;  5K23 A;  1KAK A;  1BZH A;  1PTV A;  2PT0 A;  3ZM1 A;  4GRY A;  2VEV A;  2AZR A;  4GE5 A;  1EEO A;  5KA0 A;  2SHP A;  3U96 A;  2F6Y A;  4Y14 A;  1Q6S A;  2HC1 A;  3O4S A;  5BZX A;  1JF7 A;  2CNE A;  5M43 A;  1M3G A;  5HDE A;  4D3R A;  4I8N A;  2J17 A;  2GJT A;  4BJO A;  2HNQ A;  2QBP A;  1OEV A;  2J16 A;  2I4E A;  4HRF A;  4GFU A;  3QCG A;  2A8B A;  1NL9 A;  2B4P A;  2I1Y A;  1LQF A;  1ZCL A;  3H2X A;  1Q6N A;  2B4U A;  5KAA A;  1X24 A;  4Y2E A;  1OHC A;  2Q47 A;  4D3Q A;  2VEU A;  2I6J A;  1Q6T A;  1I9S A;  1I9T A;  1R6H A;  1PXH A;  2CNF A;  1T49 A;  3QKQ A;  3D44 A;  1G1F A;  1G4U S;  3V0F A;  3QCE A;  1C84 A;  3I80 A;  3S3F A;  4R30 A;  2QCT A;  3V0H A;  3QCH A;  1YGR A;  1NWE A;  3QCD A;  4GRZ A;  2NT7 A;  4GS0 A;  5K22 A;  3I7Z A;  2H4K A;  2G59 A;  1G7G A;  4JNB A;  4NWG A;  2PA5 A;  3A5K A;  1LAR A;  1XBO A;  3O4U A;  1V3A A;  1NO6 A;  2M3V A;  3S3H A;  4NWF A;  2F71 A;  3D1Q A;  3ZM3 A;  3QCB A;  4OHH A;  1G7F A;  2R0B A;  5AWX A;  1OET A;  2QBS A;  2OZ5 A;  2F46 A;  3CM3 A;  1PA1 A;  2ZN7 A;  2MBC A;  5EHP A;  5GTJ A;  2E0T A;  4D3P A;  3RO1 A;  2RF6 A;  1U26 A;  5LXQ B;  4QAH A;  2F6W A;  3BRH A;  1ZC0 A;  4PVG A;  4WU2 A;  4OHI A;  4HJQ A;  3B7O A;  2CM2 A;  2JJD A;  2WGP A;  5IBS A;  3RZ2 A;  4S0G A;  2PSZ A;  1YN9 A;  1SUG A;  2F70 A;  5KAD A;  4WOH A;  4NYH A;  1ECV A;  5K9W A;  4ZRT A;  5KA9 A;  2CMC A;  3F99 A;  3V0G A;  2CM8 A;  1PTT A;  3O3L A;  1VHR A;  1YZ4 A;  1QXK A;  2H04 A;  3ZM0 A;  1FPZ A;  1OHD A;  2HY3 A;  3AWG A;  4ZN5 A;  3QCL A;  3GXG A;  1PA9 A;  4AZ1 A;  2VEY A;  2H02 A;  4ERC A;  1J4X A;  2H4G A;  2NLK A;  1YTN A;  2CJZ A;  3QCN A;  4RH9 A;  3CWE A;  3EU0 A;  1ONY A;  3I36 A;  1OEM X;  2I6I A;  1NNY A;  2BGE A;  2CNG A;  2I6P A;  4JBC A;  5KA8 A;  2F6F A;  2I5X A;  1G1H A;  3QCK A;  4GE6 A;  4H1O A;  5BUG A;  1YGU A; 
#chains in the Genus database with same CATH topology
 5K25 A;  5KA4 A;  1E0D A;  1YWF A;  2GCA A;  2CMA A;  2F6V A;  5MMZ B;  1Q1M A;  1EEH A;  2F6Z A;  2QDM A;  2XPC A;  1FQ1 A;  1GFY A;  1XRI A;  3V0E A;  2HC2 A;  1C85 A;  4RKK A;  1WCH A;  3BM8 A;  1YTS A;  2CFV A;  4B04 A;  2I6M A;  1XXP A;  3EZZ A;  1JLN A;  3V0D A;  1OEU A;  5KA1 A;  2PBN A;  3V0I A;  4OHD A;  1BZC A;  1MKP A;  4KYR A;  2H03 A;  3BLT A;  1ZZW A;  2BGD A;  1PTY A;  4GFV A;  1P15 A;  3V0J A;  4CVM A;  2AM1 A;  3RGO A;  2NZ6 A;  1L8K A;  1E8C A;  4QBW A;  1AAX A;  2CNH A;  2QCJ A;  2F00 A;  2BV5 A;  3QCZ A;  3M4U A;  2HNP A;  2P6X A;  2VEW A;  5KAB A;  2Y2F A;  2B3O A;  4QBE A;  2HCM A;  1ONZ A;  1OEO X;  5IBM A;  4QUN A;  2QEP A;  4ZIY A;  4RI4 A;  2QBR A;  1NZ7 A;  3O5X A;  4H34 A;  1XM2 A;  3EB1 A;  2NTA A;  1GWZ A;  5BZZ A;  2FJN A;  3O4T A;  5KA3 A;  1C87 A;  4KYQ A;  5K24 A;  2GWO A;  1YFO A;  3S3E A;  4WU3 A;  1QZ0 A;  3QCJ A;  2AHS A;  2Y96 A;  3S3K A;  1O5Z A;  3RGQ A;  3MOZ A;  2BZL A;  4ZI4 A;  5EHR A;  2Y66 A;  1Q6J A;  1RXD A;  2I3U A;  4JMK A;  2HB1 A;  4IKC A;  1A5Y A;  1U24 A;  1P3D A;  2FH7 A;  2NT2 A;  4QAP A;  2HXP A;  1RPM A;  3OMH A;  1L8G A;  2IMG A;  2I3R A;  3LK7 A;  2OUD A;  1OHE A;  3S4E A;  2CMB A;  4HV4 A;  2VOR A;  4QUM A;  3N0A A;  3AWF A;  2HVL A;  1D5R A;  2VTE A;  3F9B A;  2PI7 A;  2B4O A;  2VOS A;  3D1H A;  4CVL A;  3D1O A;  4OHE A;  1NWL A;  3GXH A;  3SR9 A;  1ZCK A;  4BPC A;  5J8R A;  3ZMQ A;  2ZMM A;  2UUP A;  5I6V A;  3BLU A;  3SME A;  2VTD A;  4J51 A;  2I4G A;  2QDP A;  2CM3 A;  1W78 A;  1C83 A;  4NND A;  4Z6B A;  2DXP A;  2WJP A;  1PYN A;  4TVV A;  4RHG A;  1KAV A;  2BIJ A;  4PYH A;  2NV5 A;  4GE2 A;  2H4V A;  2I75 A;  3QCC A;  2QDC A;  3EMU A;  1PTU A;  2OOQ A;  3MOW A;  2A3K A;  3F41 A;  4ICZ A;  2I6O A;  4GWF A;  2J16 B;  1U25 A;  3ZV2 A;  4DGX A;  3UAG A;  1C86 A;  2PQ5 A;  5KAC A;  3AWE A;  4MBB A;  3EAX A;  4R0S A;  1JBW A;  2B49 A;  3F81 A;  4RI5 A;  3QKP A;  2C46 A;  4WTY A;  4RDD A;  4DGP A;  1C88 A;  5BX1 A;  2YDU A;  2QBQ A;  1I57 A;  1XXV A;  2GC5 A;  2FJM A;  2P4D A;  4QDI A;  1GQQ A;  4RH5 A;  1YPT A;  2C7S A;  1WAX A;  1Q6M A;  3OLR A;  3D9C A;  3ZMP A;  3NRS A;  1BZJ A;  1WRM A;  1PH0 A;  4NX8 A;  2CNI A;  3S4O A;  4KI9 A;  5K9V A;  3QCF A;  2G6Z A;  4HJP A;  4YR8 B;  1G1G A;  1P31 A;  1G4W R;  1T48 A;  2B07 A;  3ZM5 A;  3A5J A;  3MMJ A;  3F9A A;  2Q05 A;  4YAA A;  1OES A;  3LJ8 A;  1GG4 A;  3D42 A;  2I42 A;  2GP0 A;  2B4S A;  4JMJ A;  1YTW A;  1EEN A;  4C12 A;  2OC3 A;  4OHL A;  3QCM A;  2I4H A;  2F6T A;  2VEX A;  2ESB A;  1Q6P A;  3PS5 A;  1LYV A;  2CM7 A;  5KA7 A;  4R0T A;  3ZM2 A;  3ZM6 A;  1T4J A;  3MVN A;  5KA2 A;  3QCI A;  1FPR A;  3NME A;  5K23 A;  1KAK A;  1BZH A;  1PTV A;  2PT0 A;  3ZM1 A;  4GRY A;  2VEV A;  2AZR A;  4GE5 A;  1EEO A;  5KA0 A;  2SHP A;  3U96 A;  2F6Y A;  4Y14 A;  1Q6S A;  2HC1 A;  3O4S A;  5BZX A;  1JF7 A;  2CNE A;  5M43 A;  1M3G A;  5HDE A;  4D3R A;  4I8N A;  2J17 A;  2GJT A;  4BJO A;  2HNQ A;  4QF5 A;  2QBP A;  1OEV A;  2J16 A;  2I4E A;  4HRF A;  3PYZ A;  4GFU A;  3QCG A;  2A8B A;  1NL9 A;  2B4P A;  2I1Y A;  1LQF A;  1ZCL A;  3H2X A;  1Q6N A;  2B4U A;  5KAA A;  1X24 A;  4UAG A;  4Y2E A;  1OHC A;  2Q47 A;  4D3Q A;  2VEU A;  2I6J A;  1Q6T A;  1I9S A;  1I9T A;  1R6H A;  3HN7 A;  1PXH A;  2CNF A;  1T49 A;  3QKQ A;  3D44 A;  1G1F A;  1G4U S;  3V0F A;  3QCE A;  1C84 A;  3I80 A;  3S3F A;  4R30 A;  2QCT A;  3V0H A;  3QCH A;  1YGR A;  1NWE A;  3QCD A;  4GRZ A;  2NT7 A;  4GS0 A;  2JFF A;  5K22 A;  4C13 A;  3I7Z A;  2AM2 A;  2H4K A;  2G59 A;  1G7G A;  2X5O A;  4JNB A;  4NWG A;  2JFG A;  2PA5 A;  3A5K A;  1LAR A;  1XBO A;  3O4U A;  1V3A A;  1NO6 A;  2M3V A;  3S3H A;  4NWF A;  2F71 A;  3D1Q A;  1UAG A;  3ZM3 A;  2GC6 A;  3QCB A;  4OHH A;  1G7F A;  2R0B A;  5AWX A;  1OET A;  2QBS A;  2OZ5 A;  2F46 A;  3CM3 A;  1PA1 A;  2ZN7 A;  2MBC A;  5EHP A;  5GTJ A;  2E0T A;  4D3P A;  3RO1 A;  2RF6 A;  1U26 A;  5LXQ B;  4QAH A;  2Y68 A;  2F6W A;  3BRH A;  1ZC0 A;  4BUC A;  4PVG A;  4WU2 A;  4OHI A;  4HJQ A;  3B7O A;  2CM2 A;  1FGS A;  2JJD A;  2WGP A;  5IBS A;  3RZ2 A;  4S0G A;  2PSZ A;  5A5F A;  1YN9 A;  1SUG A;  2F70 A;  5KAD A;  3N2A A;  4WOH A;  4NYH A;  1ECV A;  5K9W A;  4ZRT A;  5KA9 A;  2GCB A;  2CMC A;  3F99 A;  1J6U A;  3V0G A;  2CM8 A;  1PTT A;  3O3L A;  1VHR A;  1YZ4 A;  1QXK A;  2H04 A;  3ZM0 A;  2UUO A;  1FPZ A;  1OHD A;  2HY3 A;  3AWG A;  4ZN5 A;  3QCL A;  2XJA A;  3GXG A;  1PA9 A;  4AZ1 A;  2VEY A;  2H02 A;  4ERC A;  1J4X A;  2H4G A;  2NLK A;  1YTN A;  2Y67 A;  2CJZ A;  3QCN A;  4RH9 A;  2WTZ A;  3ZL8 A;  3CWE A;  4CVK A;  3EU0 A;  1GQY A;  1ONY A;  3I36 A;  2JFH A;  1OEM X;  2I6I A;  2UAG A;  1NNY A;  5A5E A;  2BGE A;  4BUB A;  2Y1O A;  2CNG A;  2I6P A;  4JBC A;  5KA8 A;  2F6F A;  2I5X A;  1G1H A;  3QCK A;  4GE6 A;  4H1O A;  1W7K A;  5BUG A;  1JBV A;  1YGU A; 
#chains in the Genus database with same CATH homology
 5K25 A;  5KA4 A;  1YWF A;  2CMA A;  2F6V A;  5MMZ B;  1Q1M A;  2F6Z A;  2QDM A;  1FQ1 A;  1GFY A;  1XRI A;  3V0E A;  2HC2 A;  1C85 A;  4RKK A;  1WCH A;  3BM8 A;  1YTS A;  2CFV A;  4B04 A;  2I6M A;  1XXP A;  3EZZ A;  1JLN A;  3V0D A;  1OEU A;  5KA1 A;  2PBN A;  3V0I A;  4OHD A;  1BZC A;  1MKP A;  4KYR A;  2H03 A;  3BLT A;  1ZZW A;  2BGD A;  1PTY A;  4GFV A;  1P15 A;  3V0J A;  3RGO A;  2NZ6 A;  1L8K A;  4QBW A;  1AAX A;  2CNH A;  2QCJ A;  2BV5 A;  3M4U A;  2HNP A;  2P6X A;  2VEW A;  5KAB A;  2Y2F A;  2B3O A;  4QBE A;  2HCM A;  1ONZ A;  1OEO X;  5IBM A;  4QUN A;  2QEP A;  4RI4 A;  2QBR A;  1NZ7 A;  3O5X A;  4H34 A;  1XM2 A;  3EB1 A;  2NTA A;  1GWZ A;  5BZZ A;  2FJN A;  3O4T A;  5KA3 A;  1C87 A;  4KYQ A;  5K24 A;  2GWO A;  1YFO A;  3S3E A;  4WU3 A;  1QZ0 A;  3QCJ A;  2AHS A;  2Y96 A;  3S3K A;  3RGQ A;  3MOZ A;  2BZL A;  4ZI4 A;  5EHR A;  1Q6J A;  1RXD A;  4JMK A;  2I3U A;  2HB1 A;  4IKC A;  1A5Y A;  1U24 A;  2FH7 A;  2NT2 A;  4QAP A;  2HXP A;  1RPM A;  3OMH A;  1L8G A;  2IMG A;  2I3R A;  2OUD A;  1OHE A;  3S4E A;  2CMB A;  4QUM A;  3N0A A;  3AWF A;  2HVL A;  1D5R A;  3F9B A;  2PI7 A;  2B4O A;  3D1H A;  3D1O A;  4OHE A;  1NWL A;  3GXH A;  3SR9 A;  1ZCK A;  4BPC A;  5J8R A;  3ZMQ A;  2ZMM A;  5I6V A;  3BLU A;  3SME A;  4J51 A;  2I4G A;  2QDP A;  2CM3 A;  4NND A;  1C83 A;  4Z6B A;  2DXP A;  1PYN A;  4TVV A;  4RHG A;  1KAV A;  2BIJ A;  4PYH A;  2NV5 A;  4GE2 A;  2H4V A;  2I75 A;  3QCC A;  2QDC A;  3EMU A;  1PTU A;  2OOQ A;  3MOW A;  2A3K A;  3F41 A;  4ICZ A;  2I6O A;  4GWF A;  2J16 B;  1U25 A;  3ZV2 A;  4DGX A;  1C86 A;  2PQ5 A;  5KAC A;  3AWE A;  4MBB A;  3EAX A;  4R0S A;  2B49 A;  3F81 A;  4RI5 A;  3QKP A;  2C46 A;  4WTY A;  4RDD A;  4DGP A;  1C88 A;  5BX1 A;  2YDU A;  2QBQ A;  1I57 A;  1XXV A;  2FJM A;  2P4D A;  4RH5 A;  1YPT A;  2C7S A;  1WAX A;  1Q6M A;  3OLR A;  3D9C A;  3ZMP A;  1BZJ A;  1WRM A;  1PH0 A;  4NX8 A;  2CNI A;  3S4O A;  4KI9 A;  5K9V A;  3QCF A;  2G6Z A;  4HJP A;  4YR8 B;  1G1G A;  1G4W R;  1T48 A;  2B07 A;  3A5J A;  3MMJ A;  3F9A A;  2Q05 A;  4YAA A;  1OES A;  3LJ8 A;  3D42 A;  2I42 A;  2GP0 A;  2B4S A;  4JMJ A;  1YTW A;  1EEN A;  2OC3 A;  4OHL A;  3QCM A;  2I4H A;  2F6T A;  2VEX A;  2ESB A;  1Q6P A;  3PS5 A;  1LYV A;  2CM7 A;  5KA7 A;  4R0T A;  3ZM2 A;  1T4J A;  5KA2 A;  3QCI A;  1FPR A;  3NME A;  5K23 A;  1KAK A;  1BZH A;  1PTV A;  2PT0 A;  3ZM1 A;  4GRY A;  2VEV A;  2AZR A;  4GE5 A;  1EEO A;  5KA0 A;  2SHP A;  3U96 A;  2F6Y A;  4Y14 A;  1Q6S A;  2HC1 A;  3O4S A;  5BZX A;  1JF7 A;  2CNE A;  5M43 A;  1M3G A;  5HDE A;  4D3R A;  4I8N A;  2J17 A;  2GJT A;  4BJO A;  2HNQ A;  2QBP A;  1OEV A;  2J16 A;  2I4E A;  4HRF A;  4GFU A;  3QCG A;  2A8B A;  1NL9 A;  2B4P A;  2I1Y A;  1LQF A;  1ZCL A;  3H2X A;  1Q6N A;  2B4U A;  5KAA A;  1X24 A;  4Y2E A;  1OHC A;  2Q47 A;  4D3Q A;  2VEU A;  2I6J A;  1Q6T A;  1I9S A;  1I9T A;  1R6H A;  1PXH A;  2CNF A;  1T49 A;  3QKQ A;  3D44 A;  1G1F A;  1G4U S;  3V0F A;  3QCE A;  1C84 A;  3I80 A;  3S3F A;  4R30 A;  2QCT A;  3V0H A;  3QCH A;  1YGR A;  1NWE A;  3QCD A;  4GRZ A;  2NT7 A;  4GS0 A;  5K22 A;  3I7Z A;  2H4K A;  2G59 A;  1G7G A;  4JNB A;  4NWG A;  2PA5 A;  3A5K A;  1LAR A;  1XBO A;  3O4U A;  1V3A A;  1NO6 A;  2M3V A;  3S3H A;  4NWF A;  2F71 A;  3D1Q A;  3ZM3 A;  3QCB A;  4OHH A;  1G7F A;  2R0B A;  5AWX A;  1OET A;  2QBS A;  2OZ5 A;  2F46 A;  3CM3 A;  1PA1 A;  2ZN7 A;  2MBC A;  5EHP A;  5GTJ A;  2E0T A;  4D3P A;  3RO1 A;  2RF6 A;  1U26 A;  5LXQ B;  4QAH A;  2F6W A;  3BRH A;  1ZC0 A;  4PVG A;  4WU2 A;  4OHI A;  4HJQ A;  3B7O A;  2CM2 A;  2JJD A;  2WGP A;  5IBS A;  3RZ2 A;  4S0G A;  2PSZ A;  1YN9 A;  1SUG A;  2F70 A;  5KAD A;  4WOH A;  4NYH A;  1ECV A;  5K9W A;  4ZRT A;  5KA9 A;  2CMC A;  3F99 A;  3V0G A;  2CM8 A;  1PTT A;  3O3L A;  1VHR A;  1YZ4 A;  1QXK A;  2H04 A;  3ZM0 A;  1FPZ A;  1OHD A;  2HY3 A;  3AWG A;  4ZN5 A;  3QCL A;  3GXG A;  1PA9 A;  4AZ1 A;  2VEY A;  2H02 A;  4ERC A;  1J4X A;  2H4G A;  2NLK A;  1YTN A;  2CJZ A;  3QCN A;  4RH9 A;  3CWE A;  3EU0 A;  1ONY A;  3I36 A;  1OEM X;  2I6I A;  1NNY A;  2BGE A;  2CNG A;  2I6P A;  4JBC A;  5KA8 A;  2F6F A;  2I5X A;  1G1H A;  3QCK A;  4GE6 A;  4H1O A;  5BUG A;  1YGU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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