3B8HB

Structure of the eef2-exoa(e546a)-nad+ complex
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
207
structure length
207
Chain Sequence
AFLGDGGDVSFSTRGTQNWTVERLLQAHRQLEERGYVFVGYHGTFLEAAQSIVFGGVRARSQDLDAIWRGFYIAGDPALAYGYAQDQEPDARGRIRNGALLRVYVPRSSLPGFYRTSLTLAAPEAAGEVERLIGHPLPLRLDAITGPAEEGGRLETILGWPLAERTVVIPSAIPTDPRNVGGDLDPSSIPDKEQAISALPDYASQPG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Biosynthetic protein/transferase
molecule keywords Elongation factor 2
publication title The nature and character of the transition state for the ADP-ribosyltransferase reaction.
pubmed doi rcsb
source organism Pseudomonas aeruginosa
total genus 50
structure length 207
sequence length 207
chains with identical sequence D, F
ec nomenclature ec 2.4.2.36: NAD(+)--diphthamide ADP-ribosyltransferase.
pdb deposition date 2007-11-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF09009 Exotox-A_cataly Exotoxin A catalytic
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.175.10 Alpha Beta Alpha-Beta Complex Diphtheria Toxin; domain 1 Diphtheria Toxin, domain 1 3b8hB00
1IKPA 1DTPA 1ZM2B 1MDTA 1XDTT 1DMAA 5I82A 3KI6A 3KI1A 1XK9A 3B8HB 1DDTA 3KI3A 3NY6A 3KI7A 1ZM9B 3Q9OA 2Q5TA 3KI5A 1AERA 1SGKA 3B82B 1F0LA 3B78B 2Q6MA 3KI2A 1IKQA 3KI0A 4OW6A 1TOXA 3KI4A 3ESSA 1ZM3B 4AE1A 1ZM4B 4AE0A 2ZITB
chains in the Genus database with same CATH superfamily
1IKPA 1DTPA 1ZM2B 1MDTA 1XDTT 1DMAA 5I82A 3KI6A 3KI1A 1XK9A 3B8HB 1DDTA 3KI3A 3NY6A 3KI7A 1ZM9B 3Q9OA 2Q5TA 3KI5A 1AERA 1SGKA 3B82B 1F0LA 3B78B 2Q6MA 3KI2A 1IKQA 3KI0A 4OW6A 1TOXA 3KI4A 3ESSA 1ZM3B 4AE1A 1ZM4B 4AE0A 2ZITB
chains in the Genus database with same CATH topology
1IKPA 1DTPA 1ZM2B 1MDTA 1XDTT 1DMAA 5I82A 3KI6A 3KI1A 1XK9A 3B8HB 1DDTA 3KI3A 3NY6A 3KI7A 1ZM9B 3Q9OA 2Q5TA 3KI5A 1AERA 1SGKA 3B82B 1F0LA 3B78B 2Q6MA 3KI2A 1IKQA 3KI0A 4OW6A 1TOXA 3KI4A 3ESSA 1ZM3B 4AE1A 1ZM4B 4AE0A 2ZITB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1IKP A;  1DTP A;  1ZM2 B;  1MDT A;  1XDT T;  1DMA A;  5I82 A;  3KI6 A;  3KI1 A;  1XK9 A;  3B8H B;  1DDT A;  3KI3 A;  3NY6 A;  3KI7 A;  1ZM9 B;  3Q9O A;  2Q5T A;  3KI5 A;  1AER A;  1SGK A;  3B82 B;  1F0L A;  3B78 B;  2Q6M A;  3KI2 A;  1IKQ A;  3KI0 A;  4OW6 A;  1TOX A;  3KI4 A;  3ESS A;  1ZM3 B;  4AE1 A;  1ZM4 B;  4AE0 A;  2ZIT B; 
#chains in the Genus database with same CATH topology
 1IKP A;  1DTP A;  1ZM2 B;  1MDT A;  1XDT T;  1DMA A;  5I82 A;  3KI6 A;  3KI1 A;  1XK9 A;  3B8H B;  1DDT A;  3KI3 A;  3NY6 A;  3KI7 A;  1ZM9 B;  3Q9O A;  2Q5T A;  3KI5 A;  1AER A;  1SGK A;  3B82 B;  1F0L A;  3B78 B;  2Q6M A;  3KI2 A;  1IKQ A;  3KI0 A;  4OW6 A;  1TOX A;  3KI4 A;  3ESS A;  1ZM3 B;  4AE1 A;  1ZM4 B;  4AE0 A;  2ZIT B; 
#chains in the Genus database with same CATH homology
 1IKP A;  1DTP A;  1ZM2 B;  1MDT A;  1XDT T;  1DMA A;  5I82 A;  3KI6 A;  3KI1 A;  1XK9 A;  3B8H B;  1DDT A;  3KI3 A;  3NY6 A;  3KI7 A;  1ZM9 B;  3Q9O A;  2Q5T A;  3KI5 A;  1AER A;  1SGK A;  3B82 B;  1F0L A;  3B78 B;  2Q6M A;  3KI2 A;  1IKQ A;  3KI0 A;  4OW6 A;  1TOX A;  3KI4 A;  3ESS A;  1ZM3 B;  4AE1 A;  1ZM4 B;  4AE0 A;  2ZIT B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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