3BBHA

M. jannaschii nep1 complexed with sinefungin
Total Genus 69
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
69
Knots found
sequence length
204
structure length
204
Chain Sequence
TYNIILAKSALELIPEEIKNKIRKSRVYKYDILDSNYHYKAMEKLKDKEMRGRPDIIHISLLNILDSPINHEKKLNIYIHTYDDKVLKINPETRLPRNYFRFLGVMEKVLKGERNHLIKMEEKTLEDLLNEINAKKIAIMTKTGKLTHPKLLKEYDTFIIGGFPYGKLKINKEKVFGDIKEISIYNKGLMAWTVCGIICYSLSF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The crystal structure of Nep1 reveals an extended SPOUT-class methyltransferase fold and a pre-organized SAM-binding site.
pubmed doi rcsb
molecule tags Transferase
source organism Methanocaldococcus jannaschii
molecule keywords Ribosome biogenesis protein NEP1-like
total genus 69
structure length 204
sequence length 204
chains with identical sequence B
other databases KnotProt 2.0: K +31
ec nomenclature
pdb deposition date 2007-11-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03587 EMG1 EMG1/NEP1 methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 3bbhA00
4YQPA 3OIIA 4KGNA 4JAKA 1V2XA 1GZ0A 1Z85A 2Z0YA 1X7PA 4YQQA 1VHKA 3NK7A 4YQDA 4YQTA 4YQ4A 3GYQA 3AIAA 2O3AA 3IEFA 3BBHA 4J3CA 5D9FA 5CO4A 1K3RA 4YQCA 3IC6A 1MXIA 5GMBA 2CX8A 4CNEA 4MCBA 4L69A 4YQ8A 1P9PA 2V3KA 4YPXA 3L8UA 4E8BA 4YVGA 2QMMA 2V3JA 1V6ZA 4CNGA 3KY7A 1UALA 4YQBA 4YQ9A 2YY8A 4YQ6A 2HA8A 4KDZA 4YQ0A 1O6DA 4YQ7A 1UAKA 4YQIA 3E5YA 4YQLA 3ONPA 4YQOA 4MCCA 4YPWA 3OINA 5GM8A 1X7OA 5GMCA 1NXZA 4H3ZA 3OIJA 4CNFA 1VHYA 1J85A 4YPZA 4IG6A 1UAMA 5FAIA 3NK6A 4YQNA 1VH0A 2I6DA 4YPYA 4FAKA 3O7BA 4YVHA 4YQ2A 2QWVA 4CNDA 1NS5A 4YQSA 1UAJA 3ILKA 4X3LA 4YVKA 4X3MA 4YQKA 4YQGA 4YQRA 1TO0A 3KW2A 4JALA 1ZJRA 4PZKA 4YQJA 4YQ5A 4YVIA 4YVJA 2EGWA 3AI9X 3AXZA 4YQAA 3QUVA 3BBEA 3DCMX 4RG1A 3KTYA 4YQ1A 4H3YA 3N4KA 3N4JA 4YQ3A 3KNUA 1OY5A 4MCDA 2EGVA 1IPAA 4XBOA 3BBDA
chains in the Genus database with same CATH superfamily
4YQPA 3OIIA 4KGNA 4JAKA 1V2XA 1GZ0A 1Z85A 2Z0YA 1X7PA 4YQQA 1VHKA 3NK7A 4YQDA 4YQTA 4YQ4A 3GYQA 3AIAA 2O3AA 3IEFA 3BBHA 4J3CA 5D9FA 5CO4A 1K3RA 4JWFA 4YQCA 3IC6A 1MXIA 5GMBA 2CX8A 4CNEA 4MCBA 4L69A 4YQ8A 1P9PA 2V3KA 4YPXA 3L8UA 4E8BA 4YVGA 2QMMA 2V3JA 1V6ZA 4CNGA 3KY7A 1UALA 4YQBA 4YQ9A 2YY8A 4YQ6A 2HA8A 4KDZA 4YQ0A 1O6DA 4YQ7A 1UAKA 4YQIA 3E5YA 4YQLA 3ONPA 4YQOA 4MCCA 4YPWA 3OINA 5GM8A 1X7OA 5GMCA 1NXZA 4H3ZA 3OIJA 4CNFA 1VHYA 1J85A 4YPZA 4IG6A 1UAMA 5FAIA 3NK6A 4YQNA 1VH0A 2I6DA 4YPYA 4FAKA 3O7BA 4YVHA 4YQ2A 2QWVA 4CNDA 1NS5A 4YQSA 1UAJA 3ILKA 4X3LA 4YVKA 4X3MA 4YQKA 4YQGA 4YQRA 1TO0A 4JWHA 3KW2A 4JALA 1ZJRA 4PZKA 4YQJA 4YQ5A 4YVIA 4YVJA 2EGWA 3AI9X 4JWJA 4JWGA 3AXZA 4YQAA 3QUVA 3BBEA 3DCMX 4RG1A 3KTYA 4YQ1A 4FMWA 4H3YA 3N4KA 3N4JA 4YQ3A 3KNUA 1OY5A 4MCDA 2EGVA 1IPAA 4XBOA 3BBDA
chains in the Genus database with same CATH topology
4YQPA 3OIIA 4KGNA 4JAKA 1V2XA 1GZ0A 1Z85A 2Z0YA 1X7PA 4YQQA 1VHKA 3NK7A 4YQDA 4YQTA 4YQ4A 3GYQA 3AIAA 2O3AA 3IEFA 3BBHA 4J3CA 5D9FA 5CO4A 1K3RA 4JWFA 4YQCA 3IC6A 1MXIA 5GMBA 2CX8A 4CNEA 4MCBA 4L69A 4YQ8A 1P9PA 2V3KA 4YPXA 3L8UA 4E8BA 4YVGA 2QMMA 2V3JA 1V6ZA 4CNGA 3KY7A 1UALA 4YQBA 4YQ9A 2YY8A 4YQ6A 2HA8A 4KDZA 4YQ0A 1O6DA 4YQ7A 1UAKA 4YQIA 3E5YA 4YQLA 3ONPA 4YQOA 4MCCA 4YPWA 3OINA 5GM8A 1X7OA 5GMCA 1NXZA 4H3ZA 3OIJA 4CNFA 1VHYA 1J85A 4YPZA 4IG6A 1UAMA 5FAIA 3NK6A 4YQNA 1VH0A 2I6DA 4YPYA 4FAKA 3O7BA 4YVHA 4YQ2A 2QWVA 4CNDA 1NS5A 4YQSA 1UAJA 3ILKA 4X3LA 4YVKA 4X3MA 4YQKA 4YQGA 4YQRA 1TO0A 4JWHA 3KW2A 4JALA 1ZJRA 4PZKA 4YQJA 4YQ5A 4YVIA 4YVJA 2EGWA 3AI9X 4JWJA 4JWGA 3AXZA 4YQAA 3QUVA 3BBEA 3DCMX 4RG1A 3KTYA 4YQ1A 4FMWA 4H3YA 3N4KA 3N4JA 4YQ3A 3KNUA 1OY5A 4MCDA 2EGVA 1IPAA 4XBOA 3BBDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YQP A;  3OII A;  4KGN A;  4JAK A;  1V2X A;  1GZ0 A;  1Z85 A;  2Z0Y A;  1X7P A;  4YQQ A;  1VHK A;  3NK7 A;  4YQD A;  4YQT A;  4YQ4 A;  3GYQ A;  3AIA A;  2O3A A;  3IEF A;  3BBH A;  4J3C A;  5D9F A;  5CO4 A;  1K3R A;  4YQC A;  3IC6 A;  1MXI A;  5GMB A;  2CX8 A;  4CNE A;  4MCB A;  4L69 A;  4YQ8 A;  1P9P A;  2V3K A;  4YPX A;  3L8U A;  4E8B A;  4YVG A;  2QMM A;  2V3J A;  1V6Z A;  4CNG A;  3KY7 A;  1UAL A;  4YQB A;  4YQ9 A;  2YY8 A;  4YQ6 A;  2HA8 A;  4KDZ A;  4YQ0 A;  1O6D A;  4YQ7 A;  1UAK A;  4YQI A;  3E5Y A;  4YQL A;  3ONP A;  4YQO A;  4MCC A;  4YPW A;  3OIN A;  5GM8 A;  1X7O A;  5GMC A;  1NXZ A;  4H3Z A;  3OIJ A;  4CNF A;  1VHY A;  1J85 A;  4YPZ A;  4IG6 A;  1UAM A;  5FAI A;  3NK6 A;  4YQN A;  1VH0 A;  2I6D A;  4YPY A;  4FAK A;  3O7B A;  4YVH A;  4YQ2 A;  2QWV A;  4CND A;  1NS5 A;  4YQS A;  1UAJ A;  3ILK A;  4X3L A;  4YVK A;  4X3M A;  4YQK A;  4YQG A;  4YQR A;  1TO0 A;  3KW2 A;  4JAL A;  1ZJR A;  4PZK A;  4YQJ A;  4YQ5 A;  4YVI A;  4YVJ A;  2EGW A;  3AI9 X;  3AXZ A;  4YQA A;  3QUV A;  3BBE A;  3DCM X;  4RG1 A;  3KTY A;  4YQ1 A;  4H3Y A;  3N4K A;  3N4J A;  4YQ3 A;  3KNU A;  1OY5 A;  4MCD A;  2EGV A;  1IPA A;  4XBO A;  3BBD A; 
#chains in the Genus database with same CATH topology
 4YQP A;  3OII A;  4KGN A;  4JAK A;  1V2X A;  1GZ0 A;  1Z85 A;  2Z0Y A;  1X7P A;  4YQQ A;  1VHK A;  3NK7 A;  4YQD A;  4YQT A;  4YQ4 A;  3GYQ A;  3AIA A;  2O3A A;  3IEF A;  3BBH A;  4J3C A;  5D9F A;  5CO4 A;  1K3R A;  4JWF A;  4YQC A;  3IC6 A;  1MXI A;  5GMB A;  2CX8 A;  4CNE A;  4MCB A;  4L69 A;  4YQ8 A;  1P9P A;  2V3K A;  4YPX A;  3L8U A;  4E8B A;  4YVG A;  2QMM A;  2V3J A;  1V6Z A;  4CNG A;  3KY7 A;  1UAL A;  4YQB A;  4YQ9 A;  2YY8 A;  4YQ6 A;  2HA8 A;  4KDZ A;  4YQ0 A;  1O6D A;  4YQ7 A;  1UAK A;  4YQI A;  3E5Y A;  4YQL A;  3ONP A;  4YQO A;  4MCC A;  4YPW A;  3OIN A;  5GM8 A;  1X7O A;  5GMC A;  1NXZ A;  4H3Z A;  3OIJ A;  4CNF A;  1VHY A;  1J85 A;  4YPZ A;  4IG6 A;  1UAM A;  5FAI A;  3NK6 A;  4YQN A;  1VH0 A;  2I6D A;  4YPY A;  4FAK A;  3O7B A;  4YVH A;  4YQ2 A;  2QWV A;  4CND A;  1NS5 A;  4YQS A;  1UAJ A;  3ILK A;  4X3L A;  4YVK A;  4X3M A;  4YQK A;  4YQG A;  4YQR A;  1TO0 A;  4JWH A;  3KW2 A;  4JAL A;  1ZJR A;  4PZK A;  4YQJ A;  4YQ5 A;  4YVI A;  4YVJ A;  2EGW A;  3AI9 X;  4JWJ A;  4JWG A;  3AXZ A;  4YQA A;  3QUV A;  3BBE A;  3DCM X;  4RG1 A;  3KTY A;  4YQ1 A;  4FMW A;  4H3Y A;  3N4K A;  3N4J A;  4YQ3 A;  3KNU A;  1OY5 A;  4MCD A;  2EGV A;  1IPA A;  4XBO A;  3BBD A; 
#chains in the Genus database with same CATH homology
 4YQP A;  3OII A;  4KGN A;  4JAK A;  1V2X A;  1GZ0 A;  1Z85 A;  2Z0Y A;  1X7P A;  4YQQ A;  1VHK A;  3NK7 A;  4YQD A;  4YQT A;  4YQ4 A;  3GYQ A;  3AIA A;  2O3A A;  3IEF A;  3BBH A;  4J3C A;  5D9F A;  5CO4 A;  1K3R A;  4JWF A;  4YQC A;  3IC6 A;  1MXI A;  5GMB A;  2CX8 A;  4CNE A;  4MCB A;  4L69 A;  4YQ8 A;  1P9P A;  2V3K A;  4YPX A;  3L8U A;  4E8B A;  4YVG A;  2QMM A;  2V3J A;  1V6Z A;  4CNG A;  3KY7 A;  1UAL A;  4YQB A;  4YQ9 A;  2YY8 A;  4YQ6 A;  2HA8 A;  4KDZ A;  4YQ0 A;  1O6D A;  4YQ7 A;  1UAK A;  4YQI A;  3E5Y A;  4YQL A;  3ONP A;  4YQO A;  4MCC A;  4YPW A;  3OIN A;  5GM8 A;  1X7O A;  5GMC A;  1NXZ A;  4H3Z A;  3OIJ A;  4CNF A;  1VHY A;  1J85 A;  4YPZ A;  4IG6 A;  1UAM A;  5FAI A;  3NK6 A;  4YQN A;  1VH0 A;  2I6D A;  4YPY A;  4FAK A;  3O7B A;  4YVH A;  4YQ2 A;  2QWV A;  4CND A;  1NS5 A;  4YQS A;  1UAJ A;  3ILK A;  4X3L A;  4YVK A;  4X3M A;  4YQK A;  4YQG A;  4YQR A;  1TO0 A;  4JWH A;  3KW2 A;  4JAL A;  1ZJR A;  4PZK A;  4YQJ A;  4YQ5 A;  4YVI A;  4YVJ A;  2EGW A;  3AI9 X;  4JWJ A;  4JWG A;  3AXZ A;  4YQA A;  3QUV A;  3BBE A;  3DCM X;  4RG1 A;  3KTY A;  4YQ1 A;  4FMW A;  4H3Y A;  3N4K A;  3N4J A;  4YQ3 A;  3KNU A;  1OY5 A;  4MCD A;  2EGV A;  1IPA A;  4XBO A;  3BBD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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