3BLTA

Crystal structures of yoph complexed with pvsn and pvs, inhibitors of yoph which co-valent bind to cys of active site
Total Genus 95
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
95
sequence length
282
structure length
282
Chain Sequence
SPYGPEARAELSSRLTTLRNTLAPATNDPRYLQACGGEKLNRFRDIQCRRQTAVRADLNANYIQVGNTRTIACQYPLQSQLESHFRMLAENRTPVLAVLASSSEIANQRFGMPDYFRQSGTYGSITVESKMTQQVGLGDGIMADMYTLTIREAGQKTISVPVVHVGNWPDQTAVSSEVTKALASLVDQTAETKRNMYESKGSSAVADDSKLRPVIHCRAGVGRTAQLIGAMCMNDSRNSQLSVEDMVSQMRVQRNGIMVQKDEQLDVLIKLAEGQGRPLLNS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Hydrolase
source organism Yersinia enterocolitica
publication title Aryl vinyl sulfonates and sulfones as active site-directed and mechanism-based probes for protein tyrosine phosphatases.
pubmed doi rcsb
molecule keywords Tyrosine-protein phosphatase yopH
total genus 95
structure length 282
sequence length 282
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2007-12-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 3bltA00
2E0TA 2F6YA 4PYHA 4ZRTA 3BM8A 1T4JA 1I9SA 1ZCLA 5KA2A 2ZN7A 1C84A 1G4WR 5BZZA 1NWLA 4R0SA 5MMZB 2HNPA 2B4UA 3MMJA 1OEMX 1U24A 1PXHA 4RHGA 2AZRA 1V3AA 3O3LA 3F9AA 1OEVA 3BRHA 1QZ0A 5K23A 2CJZA 2CM7A 1Q6MA 1SUGA 5KA9A 4BPCA 4QAHA 5IBSA 1ZC0A 2QCJA 3ZV2A 1YTNA 5GTJA 1P15A 1XBOA 4ICZA 4RKKA 2VEVA 4GE6A 3ZMPA 1YGUA 3QCJA 2QDCA 3EU0A 2CNEA 1ECVA 1U26A 4H1OA 4JNBA 3O4UA 3ZM3A 2PSZA 3GXHA 1LQFA 4D3QA 2I6MA 2F71A 2QBQA 2I1YA 4GFUA 2PA5A 3I36A 3AWFA 2HC1A 1NO6A 4HJQA 2QEPA 5HDEA 3QCCA 4OHLA 3S4OA 2F6VA 2P4DA 3QCGA 4Y2EA 1YTSA 1X24A 1T48A 2PI7A 2CM2A 3GXGA 3ZMQA 3B7OA 2HY3A 2NT7A 1FPRA 1Q6SA 5KA0A 3F99A 5M43A 2ZMMA 5BX1A 1BZHA 2CFVA 4PVGA 3M4UA 2SHPA 3V0HA 2B4OA 2QDMA 2I5XA 2CNFA 5K9VA 2CMCA 4GE2A 4JMKA 2B49A 2C46A 2HB1A 2OUDA 3EB1A 1G4US 1Q6NA 5KA1A 1C83A 1ZZWA 1PTTA 2F6FA 1C85A 3QKPA 4RDDA 2PBNA 1Q1MA 1XXVA 3S3HA 3SMEA 5K9WA 1T49A 3O5XA 3AWGA 4R0TA 3QKQA 2HCMA 2NT2A 2NLKA 2I75A 3S3KA 2VEYA 1Q6TA 4QUNA 1KAVA 1C88A 4QUMA 3S3EA 2I6PA 3F41A 1PH0A 2DXPA 4I8NA 4D3PA 5K22A 4HJPA 2B07A 2OC3A 3D1HA 5BZXA 2YDUA 3NMEA 2NZ6A 5J8RA 2Q47A 1NNYA 1Q6JA 3V0EA 1XXPA 3QCMA 2VEUA 4GRZA 1XRIA 2A8BA 4H34A 4QAPA 1OHDA 1NZ7A 1YN9A 5EHPA 5KADA 4WOHA 4QBEA 4NYHA 2AHSA 1M3GA 1OEOX 2FJNA 5K25A 5EHRA 5AWXA 1R6HA 1PTVA 4KI9A 5KAAA 3QCBA 5KA7A 1WRMA 3A5JA 1NWEA 4DGXA 1PTUA 1YTWA 2QDPA 4J51A 1EENA 1WCHA 4WU3A 3O4SA 2CNIA 4HRFA 2QBRA 2HNQA 2C7SA 1J4XA 4YR8B 4RI5A 3V0FA 3PS5A 2BIJA 1RXDA 3F9BA 2PQ5A 4YAAA 3RO1A 1PYNA 2H03A 3MOWA 4IKCA 2QBSA 3D44A 2I3RA 3D1QA 4GS0A 1A5YA 2NTAA 1U25A 1NL9A 2R0BA 2P6XA 5KA4A 4TVVA 3QCDA 1I57A 1LARA 1LYVA 3ZM2A 3S3FA 1ONZA 4ZI4A 4WTYA 1MKPA 4OHDA 1GFYA 2GWOA 3OLRA 1L8KA 2CM3A 2F6TA 2BV5A 4KYRA 4RH9A 2JJDA 1L8GA 4GWFA 3ZM1A 5I6VA 1OEUA 2RF6A 2H4GA 2OZ5A 2IMGA 1G1HA 2BGEA 2GJTA 3RZ2A 1BZJA 2CMAA 3QCFA 2I4GA 3ZM0A 1I9TA 2M3VA 2CMBA 4OHIA 3V0GA 2OOQA 2A3KA 1QXKA 4NWGA 4ZN5A 3D42A 3D1OA 4GFVA 2I42A 4MBBA 1OETA 3QCLA 1G1GA 2CNHA 4JMJA 3I7ZA 3RGQA 4GRYA 3EAXA 1EEOA 2F70A 2VEWA 2WGPA 3BLUA 3SR9A 2F6ZA 1FPZA 1KAKA 5LXQB 2QCTA 3EMUA 4KYQA 1BZCA 2NV5A 4DGPA 4WU2A 1XM2A 2B4PA 2B3OA 1G7FA 4S0GA 4Y14A 1YPTA 2FJMA 4GE5A 5K24A 2QBPA 2F6WA 2I6IA 4NWFA 1YGRA 4RI4A 4R30A 2J17A 1OESA 1G1FA 4B04A 1D5RA 3QCIA 3QCNA 2HC2A 3H2XA 2G59A 4AZ1A 1JF7A 4QBWA 2I6JA 3RGOA 2H04A 4JBCA 3V0JA 1PA1A 1C87A 2H4VA 2VEXA 3CM3A 2BZLA 3MOZA 4BJOA 3U96A 4NNDA 4OHHA 2G6ZA 3CWEA 3V0DA 2CM8A 3F81A 1YWFA 5KA8A 2F46A 1ONYA 1OHCA 1YFOA 5KABA 2I3UA 2MBCA 3V0IA 1JLNA 5BUGA 1OHEA 2HXPA 3QCHA 5IBMA 3EZZA 2J16A 1YZ4A 2GP0A 4RH5A 5KA3A 1Q6PA 1G7GA 3BLTA 4D3RA 3QCEA 1PTYA 1RPMA 3D9CA 2Y2FA 1C86A 4OHEA 2FH7A 3S4EA 3AWEA 3LJ8A 5KACA 4NX8A 2H02A 2H4KA 1PA9A 3O4TA 1ZCKA 2J16B 2Y96A 1AAXA 3A5KA 3QCKA 2I6OA 2ESBA 2PT0A 3N0AA 3I80A 4ERCA 2B4SA 4Z6BA 1FQ1A 2Q05A 1GWZA 2I4HA 2CNGA 1VHRA 2BGDA 3OMHA 1WAXA 2HVLA 2I4EA
chains in the Genus database with same CATH superfamily
2E0TA 2F6YA 4PYHA 4ZRTA 3BM8A 1T4JA 1I9SA 4QDIA 1ZCLA 4QF5A 5KA2A 2ZN7A 1EEHA 3QCZA 1C84A 4BUBA 1G4WR 5BZZA 1NWLA 1GQQA 4ZIYA 4R0SA 5MMZB 2HNPA 2B4UA 3MMJA 2Y66A 1OEMX 1U24A 1PXHA 4RHGA 2AZRA 1V3AA 3O3LA 3F9AA 1OEVA 2Y68A 3BRHA 1QZ0A 5K23A 2CJZA 2CM7A 1Q6MA 1SUGA 1GQYA 5KA9A 4BPCA 4QAHA 5IBSA 1ZC0A 2QCJA 1FGSA 3ZV2A 1YTNA 5GTJA 1P15A 1XBOA 4CVLA 4ICZA 4RKKA 2VEVA 4GE6A 3ZMPA 1O5ZA 1YGUA 3QCJA 2QDCA 2XJAA 3EU0A 1W78A 2CNEA 1ECVA 1U26A 4H1OA 4JNBA 3O4UA 3ZM3A 2PSZA 3GXHA 1LQFA 2XPCA 4D3QA 2I6MA 2F71A 2QBQA 2I1YA 4GFUA 2PA5A 3I36A 3AWFA 2HC1A 1NO6A 2GC6A 4HJQA 2QEPA 5HDEA 3QCCA 4OHLA 1E8CA 3S4OA 2F6VA 2P4DA 3QCGA 5A5FA 4Y2EA 1YTSA 2UAGA 1X24A 1T48A 2PI7A 2CM2A 3GXGA 3ZMQA 3B7OA 2HY3A 2NT7A 1FPRA 1Q6SA 5KA0A 3F99A 5M43A 2ZMMA 5BX1A 1W7KA 1BZHA 2CFVA 4PVGA 3M4UA 2SHPA 4C13A 3V0HA 2B4OA 2QDMA 2I5XA 4C12A 2CNFA 2VTDA 5K9VA 2VTEA 2CMCA 4GE2A 3ZL8A 4JMKA 2B49A 2C46A 2HB1A 2OUDA 3EB1A 4BUCA 1G4US 1Q6NA 5KA1A 2GCBA 1C83A 1ZZWA 1PTTA 2F6FA 1C85A 3QKPA 4RDDA 2PBNA 1Q1MA 1XXVA 3S3HA 3SMEA 5K9WA 1T49A 3O5XA 3AWGA 3ZM5A 4R0TA 3QKQA 2HCMA 2NT2A 2NLKA 2I75A 3S3KA 2VEYA 1Q6TA 4QUNA 1KAVA 2F00A 1C88A 4QUMA 3S3EA 2I6PA 2VOSA 3F41A 1PH0A 2DXPA 4I8NA 4D3PA 5K22A 4HJPA 2B07A 2OC3A 3D1HA 5BZXA 2YDUA 3NMEA 2NZ6A 5J8RA 2Q47A 1E0DA 1NNYA 1Q6JA 3V0EA 1XXPA 3QCMA 2VEUA 4GRZA 1XRIA 2A8BA 4H34A 4QAPA 1OHDA 1NZ7A 1YN9A 5EHPA 5KADA 4WOHA 4QBEA 4NYHA 4CVMA 2AHSA 1M3GA 1OEOX 2FJNA 5K25A 5EHRA 5AWXA 1R6HA 3HN7A 2GC5A 1P31A 1PTVA 4KI9A 5KAAA 3QCBA 5KA7A 1WRMA 3A5JA 1NWEA 4DGXA 1PTUA 1YTWA 2GCAA 4CVKA 2QDPA 4J51A 1EENA 2WJPA 1WCHA 4WU3A 3O4SA 2CNIA 4HRFA 2QBRA 2HNQA 2C7SA 1J4XA 3LK7A 4YR8B 4RI5A 3V0FA 3PS5A 2VORA 1GG4A 2BIJA 3MVNA 1RXDA 3F9BA 2PQ5A 4YAAA 3RO1A 1PYNA 2H03A 3MOWA 4IKCA 2QBSA 3D44A 2I3RA 3D1QA 4GS0A 1J6UA 1P3DA 1A5YA 2NTAA 1U25A 1NL9A 2R0BA 2P6XA 5KA4A 4TVVA 3QCDA 1I57A 1LARA 1LYVA 3ZM2A 3S3FA 1ONZA 4ZI4A 4WTYA 1MKPA 4OHDA 1GFYA 2GWOA 3OLRA 1L8KA 2CM3A 2F6TA 2BV5A 4KYRA 4RH9A 2JJDA 1L8GA 4GWFA 3ZM1A 5I6VA 1JBVA 1OEUA 2RF6A 2H4GA 2OZ5A 2IMGA 2X5OA 1G1HA 2BGEA 2GJTA 3RZ2A 1BZJA 2CMAA 2I4GA 3QCFA 5A5EA 3ZM0A 1I9TA 2M3VA 2CMBA 4OHIA 3V0GA 2OOQA 2A3KA 1QXKA 4NWGA 4ZN5A 3D42A 3D1OA 4GFVA 2I42A 4MBBA 1OETA 3QCLA 1G1GA 2CNHA 4JMJA 3I7ZA 3RGQA 3UAGA 4GRYA 3EAXA 1EEOA 2F70A 2VEWA 2UUPA 2WGPA 3BLUA 3SR9A 2F6ZA 1FPZA 1KAKA 5LXQB 2QCTA 3EMUA 4KYQA 1BZCA 3NRSA 2NV5A 4DGPA 4WU2A 1XM2A 2B4PA 3N2AA 2Y67A 1UAGA 2B3OA 1G7FA 4S0GA 4Y14A 1YPTA 2FJMA 2WTZA 4GE5A 5K24A 2QBPA 2F6WA 2I6IA 4NWFA 1YGRA 4RI4A 2UUOA 4R30A 2JFFA 2J17A 1OESA 1G1FA 4B04A 1D5RA 3QCIA 3QCNA 2HC2A 3H2XA 2G59A 4AZ1A 1JF7A 2Y1OA 4QBWA 2I6JA 3RGOA 2H04A 4JBCA 3V0JA 1PA1A 1C87A 2H4VA 2VEXA 3CM3A 2BZLA 3MOZA 4UAGA 4BJOA 3U96A 4NNDA 4OHHA 2G6ZA 3CWEA 2AM2A 2CM8A 3V0DA 3F81A 1YWFA 5KA8A 2F46A 3ZM6A 1ONYA 1OHCA 1YFOA 5KABA 2I3UA 2MBCA 3V0IA 1JLNA 2JFHA 5BUGA 1OHEA 2HXPA 3QCHA 5IBMA 3EZZA 2J16A 1YZ4A 2GP0A 4RH5A 4HV4A 5KA3A 1Q6PA 2JFGA 1G7GA 3BLTA 4D3RA 3QCEA 1PTYA 1RPMA 3D9CA 2Y2FA 1C86A 4OHEA 3PYZA 2FH7A 3S4EA 3AWEA 3LJ8A 5KACA 4NX8A 2H02A 2H4KA 1PA9A 3O4TA 1ZCKA 2J16B 2Y96A 1AAXA 3A5KA 3QCKA 2I6OA 2ESBA 2PT0A 3N0AA 3I80A 2AM1A 4ERCA 2B4SA 1JBWA 4Z6BA 1FQ1A 2Q05A 1GWZA 2I4HA 2CNGA 1VHRA 2BGDA 3OMHA 1WAXA 2HVLA 2I4EA
chains in the Genus database with same CATH topology
2E0TA 2F6YA 4PYHA 4ZRTA 3BM8A 1T4JA 1I9SA 1ZCLA 5KA2A 2ZN7A 1C84A 1G4WR 5BZZA 1NWLA 4R0SA 5MMZB 2HNPA 2B4UA 3MMJA 1OEMX 1U24A 1PXHA 4RHGA 2AZRA 1V3AA 3O3LA 3F9AA 1OEVA 3BRHA 1QZ0A 5K23A 2CJZA 2CM7A 1Q6MA 1SUGA 5KA9A 4BPCA 4QAHA 5IBSA 1ZC0A 2QCJA 3ZV2A 1YTNA 5GTJA 1P15A 1XBOA 4ICZA 4RKKA 2VEVA 4GE6A 3ZMPA 1YGUA 3QCJA 2QDCA 3EU0A 2CNEA 1ECVA 1U26A 4H1OA 4JNBA 3O4UA 3ZM3A 2PSZA 3GXHA 1LQFA 4D3QA 2I6MA 2F71A 2QBQA 2I1YA 4GFUA 2PA5A 3I36A 3AWFA 2HC1A 1NO6A 4HJQA 2QEPA 5HDEA 3QCCA 4OHLA 3S4OA 2F6VA 2P4DA 3QCGA 4Y2EA 1YTSA 1X24A 1T48A 2PI7A 2CM2A 3GXGA 3ZMQA 3B7OA 2HY3A 2NT7A 1FPRA 1Q6SA 5KA0A 3F99A 5M43A 2ZMMA 5BX1A 1BZHA 2CFVA 4PVGA 3M4UA 2SHPA 3V0HA 2B4OA 2QDMA 2I5XA 2CNFA 5K9VA 2CMCA 4GE2A 4JMKA 2B49A 2C46A 2HB1A 2OUDA 3EB1A 1G4US 1Q6NA 5KA1A 1C83A 1ZZWA 1PTTA 2F6FA 1C85A 3QKPA 4RDDA 2PBNA 1Q1MA 1XXVA 3S3HA 3SMEA 5K9WA 1T49A 3O5XA 3AWGA 4R0TA 3QKQA 2HCMA 2NT2A 2NLKA 2I75A 3S3KA 2VEYA 1Q6TA 4QUNA 1KAVA 1C88A 4QUMA 3S3EA 2I6PA 3F41A 1PH0A 2DXPA 4I8NA 4D3PA 5K22A 4HJPA 2B07A 2OC3A 3D1HA 5BZXA 2YDUA 3NMEA 2NZ6A 5J8RA 2Q47A 1NNYA 1Q6JA 3V0EA 1XXPA 3QCMA 2VEUA 4GRZA 1XRIA 2A8BA 4H34A 4QAPA 1OHDA 1NZ7A 1YN9A 5EHPA 5KADA 4WOHA 4QBEA 4NYHA 2AHSA 1M3GA 1OEOX 2FJNA 5K25A 5EHRA 5AWXA 1R6HA 1PTVA 4KI9A 5KAAA 3QCBA 5KA7A 1WRMA 3A5JA 1NWEA 4DGXA 1PTUA 1YTWA 2QDPA 4J51A 1EENA 1WCHA 4WU3A 3O4SA 2CNIA 4HRFA 2QBRA 2HNQA 2C7SA 1J4XA 4YR8B 4RI5A 3V0FA 3PS5A 2BIJA 1RXDA 3F9BA 2PQ5A 4YAAA 3RO1A 1PYNA 2H03A 3MOWA 4IKCA 2QBSA 3D44A 2I3RA 3D1QA 4GS0A 1A5YA 2NTAA 1U25A 1NL9A 2R0BA 2P6XA 5KA4A 4TVVA 3QCDA 1I57A 1LARA 1LYVA 3ZM2A 3S3FA 1ONZA 4ZI4A 4WTYA 1MKPA 4OHDA 1GFYA 2GWOA 3OLRA 1L8KA 2CM3A 2F6TA 2BV5A 4KYRA 4RH9A 2JJDA 1L8GA 4GWFA 3ZM1A 5I6VA 1OEUA 2RF6A 2H4GA 2OZ5A 2IMGA 1G1HA 2BGEA 2GJTA 3RZ2A 1BZJA 2CMAA 3QCFA 2I4GA 3ZM0A 1I9TA 2M3VA 2CMBA 4OHIA 3V0GA 2OOQA 2A3KA 1QXKA 4NWGA 4ZN5A 3D42A 3D1OA 4GFVA 2I42A 4MBBA 1OETA 3QCLA 1G1GA 2CNHA 4JMJA 3I7ZA 3RGQA 4GRYA 3EAXA 1EEOA 2F70A 2VEWA 2WGPA 3BLUA 3SR9A 2F6ZA 1FPZA 1KAKA 5LXQB 2QCTA 3EMUA 4KYQA 1BZCA 2NV5A 4DGPA 4WU2A 1XM2A 2B4PA 2B3OA 1G7FA 4S0GA 4Y14A 1YPTA 2FJMA 4GE5A 5K24A 2QBPA 2F6WA 2I6IA 4NWFA 1YGRA 4RI4A 4R30A 2J17A 1OESA 1G1FA 4B04A 1D5RA 3QCIA 3QCNA 2HC2A 3H2XA 2G59A 4AZ1A 1JF7A 4QBWA 2I6JA 3RGOA 2H04A 4JBCA 3V0JA 1PA1A 1C87A 2H4VA 2VEXA 3CM3A 2BZLA 3MOZA 4BJOA 3U96A 4NNDA 4OHHA 2G6ZA 3CWEA 3V0DA 2CM8A 3F81A 1YWFA 5KA8A 2F46A 1ONYA 1OHCA 1YFOA 5KABA 2I3UA 2MBCA 3V0IA 1JLNA 5BUGA 1OHEA 2HXPA 3QCHA 5IBMA 3EZZA 2J16A 1YZ4A 2GP0A 4RH5A 5KA3A 1Q6PA 1G7GA 3BLTA 4D3RA 3QCEA 1PTYA 1RPMA 3D9CA 2Y2FA 1C86A 4OHEA 2FH7A 3S4EA 3AWEA 3LJ8A 5KACA 4NX8A 2H02A 2H4KA 1PA9A 3O4TA 1ZCKA 2J16B 2Y96A 1AAXA 3A5KA 3QCKA 2I6OA 2ESBA 2PT0A 3N0AA 3I80A 4ERCA 2B4SA 4Z6BA 1FQ1A 2Q05A 1GWZA 2I4HA 2CNGA 1VHRA 2BGDA 3OMHA 1WAXA 2HVLA 2I4EA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 2E0T A;  2F6Y A;  4PYH A;  4ZRT A;  3BM8 A;  1T4J A;  1I9S A;  1ZCL A;  5KA2 A;  2ZN7 A;  1C84 A;  1G4W R;  5BZZ A;  1NWL A;  4R0S A;  5MMZ B;  2HNP A;  2B4U A;  3MMJ A;  1OEM X;  1U24 A;  1PXH A;  4RHG A;  2AZR A;  1V3A A;  3O3L A;  3F9A A;  1OEV A;  3BRH A;  1QZ0 A;  5K23 A;  2CJZ A;  2CM7 A;  1Q6M A;  1SUG A;  5KA9 A;  4BPC A;  4QAH A;  5IBS A;  1ZC0 A;  2QCJ A;  3ZV2 A;  1YTN A;  5GTJ A;  1P15 A;  1XBO A;  4ICZ A;  4RKK A;  2VEV A;  4GE6 A;  3ZMP A;  1YGU A;  3QCJ A;  2QDC A;  3EU0 A;  2CNE A;  1ECV A;  1U26 A;  4H1O A;  4JNB A;  3O4U A;  3ZM3 A;  2PSZ A;  3GXH A;  1LQF A;  4D3Q A;  2I6M A;  2F71 A;  2QBQ A;  2I1Y A;  4GFU A;  2PA5 A;  3I36 A;  3AWF A;  2HC1 A;  1NO6 A;  4HJQ A;  2QEP A;  5HDE A;  3QCC A;  4OHL A;  3S4O A;  2F6V A;  2P4D A;  3QCG A;  4Y2E A;  1YTS A;  1X24 A;  1T48 A;  2PI7 A;  2CM2 A;  3GXG A;  3ZMQ A;  3B7O A;  2HY3 A;  2NT7 A;  1FPR A;  1Q6S A;  5KA0 A;  3F99 A;  5M43 A;  2ZMM A;  5BX1 A;  1BZH A;  2CFV A;  4PVG A;  3M4U A;  2SHP A;  3V0H A;  2B4O A;  2QDM A;  2I5X A;  2CNF A;  5K9V A;  2CMC A;  4GE2 A;  4JMK A;  2B49 A;  2C46 A;  2HB1 A;  2OUD A;  3EB1 A;  1G4U S;  1Q6N A;  5KA1 A;  1C83 A;  1ZZW A;  1PTT A;  2F6F A;  1C85 A;  3QKP A;  4RDD A;  2PBN A;  1Q1M A;  1XXV A;  3S3H A;  3SME A;  5K9W A;  1T49 A;  3O5X A;  3AWG A;  4R0T A;  3QKQ A;  2HCM A;  2NT2 A;  2NLK A;  2I75 A;  3S3K A;  2VEY A;  1Q6T A;  4QUN A;  1KAV A;  1C88 A;  4QUM A;  3S3E A;  2I6P A;  3F41 A;  1PH0 A;  2DXP A;  4I8N A;  4D3P A;  5K22 A;  4HJP A;  2B07 A;  2OC3 A;  3D1H A;  5BZX A;  2YDU A;  3NME A;  2NZ6 A;  5J8R A;  2Q47 A;  1NNY A;  1Q6J A;  3V0E A;  1XXP A;  3QCM A;  2VEU A;  4GRZ A;  1XRI A;  2A8B A;  4H34 A;  4QAP A;  1OHD A;  1NZ7 A;  1YN9 A;  5EHP A;  5KAD A;  4WOH A;  4QBE A;  4NYH A;  2AHS A;  1M3G A;  1OEO X;  2FJN A;  5K25 A;  5EHR A;  5AWX A;  1R6H A;  1PTV A;  4KI9 A;  5KAA A;  3QCB A;  5KA7 A;  1WRM A;  3A5J A;  1NWE A;  4DGX A;  1PTU A;  1YTW A;  2QDP A;  4J51 A;  1EEN A;  1WCH A;  4WU3 A;  3O4S A;  2CNI A;  4HRF A;  2QBR A;  2HNQ A;  2C7S A;  1J4X A;  4YR8 B;  4RI5 A;  3V0F A;  3PS5 A;  2BIJ A;  1RXD A;  3F9B A;  2PQ5 A;  4YAA A;  3RO1 A;  1PYN A;  2H03 A;  3MOW A;  4IKC A;  2QBS A;  3D44 A;  2I3R A;  3D1Q A;  4GS0 A;  1A5Y A;  2NTA A;  1U25 A;  1NL9 A;  2R0B A;  2P6X A;  5KA4 A;  4TVV A;  3QCD A;  1I57 A;  1LAR A;  1LYV A;  3ZM2 A;  3S3F A;  1ONZ A;  4ZI4 A;  4WTY A;  1MKP A;  4OHD A;  1GFY A;  2GWO A;  3OLR A;  1L8K A;  2CM3 A;  2F6T A;  2BV5 A;  4KYR A;  4RH9 A;  2JJD A;  1L8G A;  4GWF A;  3ZM1 A;  5I6V A;  1OEU A;  2RF6 A;  2H4G A;  2OZ5 A;  2IMG A;  1G1H A;  2BGE A;  2GJT A;  3RZ2 A;  1BZJ A;  2CMA A;  3QCF A;  2I4G A;  3ZM0 A;  1I9T A;  2M3V A;  2CMB A;  4OHI A;  3V0G A;  2OOQ A;  2A3K A;  1QXK A;  4NWG A;  4ZN5 A;  3D42 A;  3D1O A;  4GFV A;  2I42 A;  4MBB A;  1OET A;  3QCL A;  1G1G A;  2CNH A;  4JMJ A;  3I7Z A;  3RGQ A;  4GRY A;  3EAX A;  1EEO A;  2F70 A;  2VEW A;  2WGP A;  3BLU A;  3SR9 A;  2F6Z A;  1FPZ A;  1KAK A;  5LXQ B;  2QCT A;  3EMU A;  4KYQ A;  1BZC A;  2NV5 A;  4DGP A;  4WU2 A;  1XM2 A;  2B4P A;  2B3O A;  1G7F A;  4S0G A;  4Y14 A;  1YPT A;  2FJM A;  4GE5 A;  5K24 A;  2QBP A;  2F6W A;  2I6I A;  4NWF A;  1YGR A;  4RI4 A;  4R30 A;  2J17 A;  1OES A;  1G1F A;  4B04 A;  1D5R A;  3QCI A;  3QCN A;  2HC2 A;  3H2X A;  2G59 A;  4AZ1 A;  1JF7 A;  4QBW A;  2I6J A;  3RGO A;  2H04 A;  4JBC A;  3V0J A;  1PA1 A;  1C87 A;  2H4V A;  2VEX A;  3CM3 A;  2BZL A;  3MOZ A;  4BJO A;  3U96 A;  4NND A;  4OHH A;  2G6Z A;  3CWE A;  3V0D A;  2CM8 A;  3F81 A;  1YWF A;  5KA8 A;  2F46 A;  1ONY A;  1OHC A;  1YFO A;  5KAB A;  2I3U A;  2MBC A;  3V0I A;  1JLN A;  5BUG A;  1OHE A;  2HXP A;  3QCH A;  5IBM A;  3EZZ A;  2J16 A;  1YZ4 A;  2GP0 A;  4RH5 A;  5KA3 A;  1Q6P A;  1G7G A;  3BLT A;  4D3R A;  3QCE A;  1PTY A;  1RPM A;  3D9C A;  2Y2F A;  1C86 A;  4OHE A;  2FH7 A;  3S4E A;  3AWE A;  3LJ8 A;  5KAC A;  4NX8 A;  2H02 A;  2H4K A;  1PA9 A;  3O4T A;  1ZCK A;  2J16 B;  2Y96 A;  1AAX A;  3A5K A;  3QCK A;  2I6O A;  2ESB A;  2PT0 A;  3N0A A;  3I80 A;  4ERC A;  2B4S A;  4Z6B A;  1FQ1 A;  2Q05 A;  1GWZ A;  2I4H A;  2CNG A;  1VHR A;  2BGD A;  3OMH A;  1WAX A;  2HVL A;  2I4E A; 
#chains in the Genus database with same CATH topology
 2E0T A;  2F6Y A;  4PYH A;  4ZRT A;  3BM8 A;  1T4J A;  1I9S A;  4QDI A;  1ZCL A;  4QF5 A;  5KA2 A;  2ZN7 A;  1EEH A;  3QCZ A;  1C84 A;  4BUB A;  1G4W R;  5BZZ A;  1NWL A;  1GQQ A;  4ZIY A;  4R0S A;  5MMZ B;  2HNP A;  2B4U A;  3MMJ A;  2Y66 A;  1OEM X;  1U24 A;  1PXH A;  4RHG A;  2AZR A;  1V3A A;  3O3L A;  3F9A A;  1OEV A;  2Y68 A;  3BRH A;  1QZ0 A;  5K23 A;  2CJZ A;  2CM7 A;  1Q6M A;  1SUG A;  1GQY A;  5KA9 A;  4BPC A;  4QAH A;  5IBS A;  1ZC0 A;  2QCJ A;  1FGS A;  3ZV2 A;  1YTN A;  5GTJ A;  1P15 A;  1XBO A;  4CVL A;  4ICZ A;  4RKK A;  2VEV A;  4GE6 A;  3ZMP A;  1O5Z A;  1YGU A;  3QCJ A;  2QDC A;  2XJA A;  3EU0 A;  1W78 A;  2CNE A;  1ECV A;  1U26 A;  4H1O A;  4JNB A;  3O4U A;  3ZM3 A;  2PSZ A;  3GXH A;  1LQF A;  2XPC A;  4D3Q A;  2I6M A;  2F71 A;  2QBQ A;  2I1Y A;  4GFU A;  2PA5 A;  3I36 A;  3AWF A;  2HC1 A;  1NO6 A;  2GC6 A;  4HJQ A;  2QEP A;  5HDE A;  3QCC A;  4OHL A;  1E8C A;  3S4O A;  2F6V A;  2P4D A;  3QCG A;  5A5F A;  4Y2E A;  1YTS A;  2UAG A;  1X24 A;  1T48 A;  2PI7 A;  2CM2 A;  3GXG A;  3ZMQ A;  3B7O A;  2HY3 A;  2NT7 A;  1FPR A;  1Q6S A;  5KA0 A;  3F99 A;  5M43 A;  2ZMM A;  5BX1 A;  1W7K A;  1BZH A;  2CFV A;  4PVG A;  3M4U A;  2SHP A;  4C13 A;  3V0H A;  2B4O A;  2QDM A;  2I5X A;  4C12 A;  2CNF A;  2VTD A;  5K9V A;  2VTE A;  2CMC A;  4GE2 A;  3ZL8 A;  4JMK A;  2B49 A;  2C46 A;  2HB1 A;  2OUD A;  3EB1 A;  4BUC A;  1G4U S;  1Q6N A;  5KA1 A;  2GCB A;  1C83 A;  1ZZW A;  1PTT A;  2F6F A;  1C85 A;  3QKP A;  4RDD A;  2PBN A;  1Q1M A;  1XXV A;  3S3H A;  3SME A;  5K9W A;  1T49 A;  3O5X A;  3AWG A;  3ZM5 A;  4R0T A;  3QKQ A;  2HCM A;  2NT2 A;  2NLK A;  2I75 A;  3S3K A;  2VEY A;  1Q6T A;  4QUN A;  1KAV A;  2F00 A;  1C88 A;  4QUM A;  3S3E A;  2I6P A;  2VOS A;  3F41 A;  1PH0 A;  2DXP A;  4I8N A;  4D3P A;  5K22 A;  4HJP A;  2B07 A;  2OC3 A;  3D1H A;  5BZX A;  2YDU A;  3NME A;  2NZ6 A;  5J8R A;  2Q47 A;  1E0D A;  1NNY A;  1Q6J A;  3V0E A;  1XXP A;  3QCM A;  2VEU A;  4GRZ A;  1XRI A;  2A8B A;  4H34 A;  4QAP A;  1OHD A;  1NZ7 A;  1YN9 A;  5EHP A;  5KAD A;  4WOH A;  4QBE A;  4NYH A;  4CVM A;  2AHS A;  1M3G A;  1OEO X;  2FJN A;  5K25 A;  5EHR A;  5AWX A;  1R6H A;  3HN7 A;  2GC5 A;  1P31 A;  1PTV A;  4KI9 A;  5KAA A;  3QCB A;  5KA7 A;  1WRM A;  3A5J A;  1NWE A;  4DGX A;  1PTU A;  1YTW A;  2GCA A;  4CVK A;  2QDP A;  4J51 A;  1EEN A;  2WJP A;  1WCH A;  4WU3 A;  3O4S A;  2CNI A;  4HRF A;  2QBR A;  2HNQ A;  2C7S A;  1J4X A;  3LK7 A;  4YR8 B;  4RI5 A;  3V0F A;  3PS5 A;  2VOR A;  1GG4 A;  2BIJ A;  3MVN A;  1RXD A;  3F9B A;  2PQ5 A;  4YAA A;  3RO1 A;  1PYN A;  2H03 A;  3MOW A;  4IKC A;  2QBS A;  3D44 A;  2I3R A;  3D1Q A;  4GS0 A;  1J6U A;  1P3D A;  1A5Y A;  2NTA A;  1U25 A;  1NL9 A;  2R0B A;  2P6X A;  5KA4 A;  4TVV A;  3QCD A;  1I57 A;  1LAR A;  1LYV A;  3ZM2 A;  3S3F A;  1ONZ A;  4ZI4 A;  4WTY A;  1MKP A;  4OHD A;  1GFY A;  2GWO A;  3OLR A;  1L8K A;  2CM3 A;  2F6T A;  2BV5 A;  4KYR A;  4RH9 A;  2JJD A;  1L8G A;  4GWF A;  3ZM1 A;  5I6V A;  1JBV A;  1OEU A;  2RF6 A;  2H4G A;  2OZ5 A;  2IMG A;  2X5O A;  1G1H A;  2BGE A;  2GJT A;  3RZ2 A;  1BZJ A;  2CMA A;  2I4G A;  3QCF A;  5A5E A;  3ZM0 A;  1I9T A;  2M3V A;  2CMB A;  4OHI A;  3V0G A;  2OOQ A;  2A3K A;  1QXK A;  4NWG A;  4ZN5 A;  3D42 A;  3D1O A;  4GFV A;  2I42 A;  4MBB A;  1OET A;  3QCL A;  1G1G A;  2CNH A;  4JMJ A;  3I7Z A;  3RGQ A;  3UAG A;  4GRY A;  3EAX A;  1EEO A;  2F70 A;  2VEW A;  2UUP A;  2WGP A;  3BLU A;  3SR9 A;  2F6Z A;  1FPZ A;  1KAK A;  5LXQ B;  2QCT A;  3EMU A;  4KYQ A;  1BZC A;  3NRS A;  2NV5 A;  4DGP A;  4WU2 A;  1XM2 A;  2B4P A;  3N2A A;  2Y67 A;  1UAG A;  2B3O A;  1G7F A;  4S0G A;  4Y14 A;  1YPT A;  2FJM A;  2WTZ A;  4GE5 A;  5K24 A;  2QBP A;  2F6W A;  2I6I A;  4NWF A;  1YGR A;  4RI4 A;  2UUO A;  4R30 A;  2JFF A;  2J17 A;  1OES A;  1G1F A;  4B04 A;  1D5R A;  3QCI A;  3QCN A;  2HC2 A;  3H2X A;  2G59 A;  4AZ1 A;  1JF7 A;  2Y1O A;  4QBW A;  2I6J A;  3RGO A;  2H04 A;  4JBC A;  3V0J A;  1PA1 A;  1C87 A;  2H4V A;  2VEX A;  3CM3 A;  2BZL A;  3MOZ A;  4UAG A;  4BJO A;  3U96 A;  4NND A;  4OHH A;  2G6Z A;  3CWE A;  2AM2 A;  2CM8 A;  3V0D A;  3F81 A;  1YWF A;  5KA8 A;  2F46 A;  3ZM6 A;  1ONY A;  1OHC A;  1YFO A;  5KAB A;  2I3U A;  2MBC A;  3V0I A;  1JLN A;  2JFH A;  5BUG A;  1OHE A;  2HXP A;  3QCH A;  5IBM A;  3EZZ A;  2J16 A;  1YZ4 A;  2GP0 A;  4RH5 A;  4HV4 A;  5KA3 A;  1Q6P A;  2JFG A;  1G7G A;  3BLT A;  4D3R A;  3QCE A;  1PTY A;  1RPM A;  3D9C A;  2Y2F A;  1C86 A;  4OHE A;  3PYZ A;  2FH7 A;  3S4E A;  3AWE A;  3LJ8 A;  5KAC A;  4NX8 A;  2H02 A;  2H4K A;  1PA9 A;  3O4T A;  1ZCK A;  2J16 B;  2Y96 A;  1AAX A;  3A5K A;  3QCK A;  2I6O A;  2ESB A;  2PT0 A;  3N0A A;  3I80 A;  2AM1 A;  4ERC A;  2B4S A;  1JBW A;  4Z6B A;  1FQ1 A;  2Q05 A;  1GWZ A;  2I4H A;  2CNG A;  1VHR A;  2BGD A;  3OMH A;  1WAX A;  2HVL A;  2I4E A; 
#chains in the Genus database with same CATH homology
 2E0T A;  2F6Y A;  4PYH A;  4ZRT A;  3BM8 A;  1T4J A;  1I9S A;  1ZCL A;  5KA2 A;  2ZN7 A;  1C84 A;  1G4W R;  5BZZ A;  1NWL A;  4R0S A;  5MMZ B;  2HNP A;  2B4U A;  3MMJ A;  1OEM X;  1U24 A;  1PXH A;  4RHG A;  2AZR A;  1V3A A;  3O3L A;  3F9A A;  1OEV A;  3BRH A;  1QZ0 A;  5K23 A;  2CJZ A;  2CM7 A;  1Q6M A;  1SUG A;  5KA9 A;  4BPC A;  4QAH A;  5IBS A;  1ZC0 A;  2QCJ A;  3ZV2 A;  1YTN A;  5GTJ A;  1P15 A;  1XBO A;  4ICZ A;  4RKK A;  2VEV A;  4GE6 A;  3ZMP A;  1YGU A;  3QCJ A;  2QDC A;  3EU0 A;  2CNE A;  1ECV A;  1U26 A;  4H1O A;  4JNB A;  3O4U A;  3ZM3 A;  2PSZ A;  3GXH A;  1LQF A;  4D3Q A;  2I6M A;  2F71 A;  2QBQ A;  2I1Y A;  4GFU A;  2PA5 A;  3I36 A;  3AWF A;  2HC1 A;  1NO6 A;  4HJQ A;  2QEP A;  5HDE A;  3QCC A;  4OHL A;  3S4O A;  2F6V A;  2P4D A;  3QCG A;  4Y2E A;  1YTS A;  1X24 A;  1T48 A;  2PI7 A;  2CM2 A;  3GXG A;  3ZMQ A;  3B7O A;  2HY3 A;  2NT7 A;  1FPR A;  1Q6S A;  5KA0 A;  3F99 A;  5M43 A;  2ZMM A;  5BX1 A;  1BZH A;  2CFV A;  4PVG A;  3M4U A;  2SHP A;  3V0H A;  2B4O A;  2QDM A;  2I5X A;  2CNF A;  5K9V A;  2CMC A;  4GE2 A;  4JMK A;  2B49 A;  2C46 A;  2HB1 A;  2OUD A;  3EB1 A;  1G4U S;  1Q6N A;  5KA1 A;  1C83 A;  1ZZW A;  1PTT A;  2F6F A;  1C85 A;  3QKP A;  4RDD A;  2PBN A;  1Q1M A;  1XXV A;  3S3H A;  3SME A;  5K9W A;  1T49 A;  3O5X A;  3AWG A;  4R0T A;  3QKQ A;  2HCM A;  2NT2 A;  2NLK A;  2I75 A;  3S3K A;  2VEY A;  1Q6T A;  4QUN A;  1KAV A;  1C88 A;  4QUM A;  3S3E A;  2I6P A;  3F41 A;  1PH0 A;  2DXP A;  4I8N A;  4D3P A;  5K22 A;  4HJP A;  2B07 A;  2OC3 A;  3D1H A;  5BZX A;  2YDU A;  3NME A;  2NZ6 A;  5J8R A;  2Q47 A;  1NNY A;  1Q6J A;  3V0E A;  1XXP A;  3QCM A;  2VEU A;  4GRZ A;  1XRI A;  2A8B A;  4H34 A;  4QAP A;  1OHD A;  1NZ7 A;  1YN9 A;  5EHP A;  5KAD A;  4WOH A;  4QBE A;  4NYH A;  2AHS A;  1M3G A;  1OEO X;  2FJN A;  5K25 A;  5EHR A;  5AWX A;  1R6H A;  1PTV A;  4KI9 A;  5KAA A;  3QCB A;  5KA7 A;  1WRM A;  3A5J A;  1NWE A;  4DGX A;  1PTU A;  1YTW A;  2QDP A;  4J51 A;  1EEN A;  1WCH A;  4WU3 A;  3O4S A;  2CNI A;  4HRF A;  2QBR A;  2HNQ A;  2C7S A;  1J4X A;  4YR8 B;  4RI5 A;  3V0F A;  3PS5 A;  2BIJ A;  1RXD A;  3F9B A;  2PQ5 A;  4YAA A;  3RO1 A;  1PYN A;  2H03 A;  3MOW A;  4IKC A;  2QBS A;  3D44 A;  2I3R A;  3D1Q A;  4GS0 A;  1A5Y A;  2NTA A;  1U25 A;  1NL9 A;  2R0B A;  2P6X A;  5KA4 A;  4TVV A;  3QCD A;  1I57 A;  1LAR A;  1LYV A;  3ZM2 A;  3S3F A;  1ONZ A;  4ZI4 A;  4WTY A;  1MKP A;  4OHD A;  1GFY A;  2GWO A;  3OLR A;  1L8K A;  2CM3 A;  2F6T A;  2BV5 A;  4KYR A;  4RH9 A;  2JJD A;  1L8G A;  4GWF A;  3ZM1 A;  5I6V A;  1OEU A;  2RF6 A;  2H4G A;  2OZ5 A;  2IMG A;  1G1H A;  2BGE A;  2GJT A;  3RZ2 A;  1BZJ A;  2CMA A;  3QCF A;  2I4G A;  3ZM0 A;  1I9T A;  2M3V A;  2CMB A;  4OHI A;  3V0G A;  2OOQ A;  2A3K A;  1QXK A;  4NWG A;  4ZN5 A;  3D42 A;  3D1O A;  4GFV A;  2I42 A;  4MBB A;  1OET A;  3QCL A;  1G1G A;  2CNH A;  4JMJ A;  3I7Z A;  3RGQ A;  4GRY A;  3EAX A;  1EEO A;  2F70 A;  2VEW A;  2WGP A;  3BLU A;  3SR9 A;  2F6Z A;  1FPZ A;  1KAK A;  5LXQ B;  2QCT A;  3EMU A;  4KYQ A;  1BZC A;  2NV5 A;  4DGP A;  4WU2 A;  1XM2 A;  2B4P A;  2B3O A;  1G7F A;  4S0G A;  4Y14 A;  1YPT A;  2FJM A;  4GE5 A;  5K24 A;  2QBP A;  2F6W A;  2I6I A;  4NWF A;  1YGR A;  4RI4 A;  4R30 A;  2J17 A;  1OES A;  1G1F A;  4B04 A;  1D5R A;  3QCI A;  3QCN A;  2HC2 A;  3H2X A;  2G59 A;  4AZ1 A;  1JF7 A;  4QBW A;  2I6J A;  3RGO A;  2H04 A;  4JBC A;  3V0J A;  1PA1 A;  1C87 A;  2H4V A;  2VEX A;  3CM3 A;  2BZL A;  3MOZ A;  4BJO A;  3U96 A;  4NND A;  4OHH A;  2G6Z A;  3CWE A;  3V0D A;  2CM8 A;  3F81 A;  1YWF A;  5KA8 A;  2F46 A;  1ONY A;  1OHC A;  1YFO A;  5KAB A;  2I3U A;  2MBC A;  3V0I A;  1JLN A;  5BUG A;  1OHE A;  2HXP A;  3QCH A;  5IBM A;  3EZZ A;  2J16 A;  1YZ4 A;  2GP0 A;  4RH5 A;  5KA3 A;  1Q6P A;  1G7G A;  3BLT A;  4D3R A;  3QCE A;  1PTY A;  1RPM A;  3D9C A;  2Y2F A;  1C86 A;  4OHE A;  2FH7 A;  3S4E A;  3AWE A;  3LJ8 A;  5KAC A;  4NX8 A;  2H02 A;  2H4K A;  1PA9 A;  3O4T A;  1ZCK A;  2J16 B;  2Y96 A;  1AAX A;  3A5K A;  3QCK A;  2I6O A;  2ESB A;  2PT0 A;  3N0A A;  3I80 A;  4ERC A;  2B4S A;  4Z6B A;  1FQ1 A;  2Q05 A;  1GWZ A;  2I4H A;  2CNG A;  1VHR A;  2BGD A;  3OMH A;  1WAX A;  2HVL A;  2I4E A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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