3BRHA

Protein tyrosine phosphatase ptpn-22 (lyp) bound to the mono-phosphorylated lck active site peptide
Total Genus 97
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
97
sequence length
296
structure length
296
Chain Sequence
QREILQKFLDEAQSKKITKEEFANEFLKLKRQSTKYKADKTYPTTVAEKPKNIKKNRYKDILPYDYSRVELSLITSDEDSSYINANFIKGVYGPKAYIATQGPLSTTLLDFWRMIWEYSVLIIVMACMEYEMGKKKCERYWAEPGEMQLEFGPFSVSCEAEKRKSDYIIRTLKVKFNSETRTIYQFHYKNWPAHDVPSSIDPILELIWDVRCYQEDDSVPICIHSSAGCGRTGVICAIDYTWMLLKDGIIPENFSVFSLIREMRTQRPSLVQTQEQYELVYNAVLELFKRQMDVIR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Lyp/PTPN22 Phosphatase Domain: Substrate Recognition and Specificity for Src family kinases
rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Tyrosine-protein phosphatase non-receptor type 22
total genus 97
structure length 296
sequence length 296
chains with identical sequence B
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2007-12-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 3brhA00
4RI5A 2F6VA 1C85A 2QBQA 2GWOA 5KAAA 3QKPA 2AZRA 2F71A 2I1YA 2CNGA 4JMJA 4ZN5A 3S3HA 2AHSA 2HXPA 4OHDA 4HJQA 3MMJA 4HRFA 1XM2A 2H4VA 5K23A 3D9CA 2CM7A 2HNPA 1XBOA 4MBBA 3GXHA 2CM8A 3D44A 4RI4A 2BIJA 5MMZB 5K9VA 2QDPA 4Y2EA 4Z6BA 3EMUA 2OC3A 1KAKA 1I57A 3AWEA 3NMEA 2ESBA 4KYRA 2H04A 1AAXA 4I8NA 3O4UA 3QCEA 4DGPA 2PT0A 3S3FA 4GE5A 3ZM1A 2NV5A 3QCNA 1G7FA 1G1GA 4AZ1A 2B4SA 1OEUA 1YGUA 1G4WR 1PTVA 3QCHA 1ZZWA 2H4GA 3V0GA 2P6XA 1G4US 1YTNA 5BUGA 2NZ6A 2I42A 3F41A 1D5RA 2I4GA 5HDEA 5KA0A 3S3EA 1YN9A 2NLKA 4BJOA 1PH0A 3S3KA 2R0BA 3QCJA 1BZCA 2H4KA 2CNEA 2QDMA 2CNIA 2PBNA 5K9WA 1OHDA 2M3VA 5I6VA 1RPMA 3SR9A 2J16A 2F70A 2CMCA 3S4EA 1XXPA 2Y2FA 2I6MA 4GFUA 2SHPA 1PA9A 1X24A 1R6HA 1T48A 2H03A 1YTSA 1OHEA 2CMBA 2QCTA 4IKCA 4RH5A 2QEPA 1Q6TA 1YGRA 1NWEA 3F81A 4R0TA 1MKPA 1YZ4A 3F9AA 3RGQA 2B3OA 2BGEA 4RHGA 5M43A 2G59A 4QAPA 5K22A 1PA1A 1ZC0A 2IMGA 1NNYA 1C87A 2QBPA 1XXVA 3CM3A 1OEOX 4GE6A 5EHRA 4GE2A 2P4DA 1Q6NA 1OEMX 1J4XA 2OZ5A 4D3RA 3O5XA 1C83A 2I75A 4YR8B 2I3UA 1NL9A 3EZZA 2JJDA 2I6PA 2Q05A 3BRHA 2HC2A 1FQ1A 1U26A 2PI7A 2I4EA 3RO1A 1ONZA 4HJPA 2ZN7A 4QUMA 1VHRA 1G1FA 3O3LA 3D1HA 3I36A 1ECVA 2A3KA 3U96A 1A5YA 3D42A 5KA8A 2CJZA 1SUGA 3ZM2A 3QCIA 3S4OA 3QCDA 5BX1A 3D1OA 4WU2A 2GP0A 2QBRA 1Q6SA 1EEOA 3N0AA 1PTUA 1WCHA 4WTYA 2I4HA 3QKQA 2Y96A 2CNHA 4KYQA 3MOZA 4GRZA 4D3PA 1ZCKA 4OHEA 2FJNA 2ZMMA 5BZXA 3EU0A 2F6ZA 1GWZA 4BPCA 4JNBA 2B49A 4S0GA 5KA2A 4GFVA 2I6IA 2F6FA 2H02A 3RGOA 1ZCLA 2HB1A 5BZZA 4GS0A 1C84A 4H1OA 1YPTA 2VEYA 2F6WA 5IBMA 2F46A 5KABA 1NWLA 1FPZA 4RKKA 3ZM0A 5KA1A 1QZ0A 1BZJA 3A5KA 3V0HA 1WRMA 2E0TA 1PXHA 1GFYA 2VEVA 3F9BA 5KA4A 4ERCA 2B4OA 4PVGA 1LYVA 3QCMA 5LXQB 3V0IA 1NO6A 2MBCA 1U24A 3F99A 1G1HA 2YDUA 4ICZA 5KA7A 1RXDA 3QCFA 3ZV2A 2I3RA 1PYNA 3OLRA 3ZMQA 1M3GA 4OHHA 2BGDA 4RDDA 2FJMA 1OHCA 1OETA 1QXKA 4GRYA 4QUNA 4OHLA 2HNQA 2B07A 1C88A 2HC1A 5KACA 3I7ZA 1V3AA 2PA5A 1G7GA 2A8BA 2NTAA 2CM3A 1EENA 1LQFA 3GXGA 2QBSA 4YAAA 3BLTA 4Y14A 5KADA 2RF6A 3I80A 2B4UA 2CNFA 2B4PA 1T49A 4ZI4A 1KAVA 4NX8A 4D3QA 4NWGA 1C86A 3QCBA 5KA3A 2HY3A 4KI9A 2FH7A 2I6OA 5J8RA 2OOQA 4NNDA 5K25A 2F6YA 2VEWA 2HVLA 3QCKA 5EHPA 2F6TA 2VEXA 1Q6MA 1I9TA 4B04A 2GJTA 1T4JA 1PTTA 4R0SA 3V0JA 2PQ5A 3ZMPA 3M4UA 3QCLA 4H34A 4WU3A 2WGPA 3EB1A 4QBEA 2PSZA 3H2XA 1OEVA 4QAHA 5IBSA 4R30A 4OHIA 2I5XA 3BLUA 4JBCA 1NZ7A 1LARA 2NT2A 3O4SA 4NYHA 1FPRA 2CM2A 2DXPA 3O4TA 1I9SA 3A5JA 3V0EA 2J16B 3AWFA 3LJ8A 3CWEA 2I6JA 3B7OA 3PS5A 4PYHA 2CMAA 3V0FA 1P15A 2BZLA 1OESA 1Q6JA 1YFOA 5GTJA 2Q47A 4QBWA 4GWFA 3BM8A 4DGXA 5K24A 1L8KA 4WOHA 3RZ2A 5KA9A 2C7SA 4NWFA 2G6ZA 1WAXA 1U25A 1YTWA 3OMHA 1ONYA 4RH9A 2CFVA 2HCMA 2QCJA 3AWGA 3EAXA 1BZHA 1PTYA 1JF7A 3D1QA 3V0DA 1JLNA 3QCCA 1Q1MA 2VEUA 2J17A 1L8GA 1Q6PA 2C46A 2NT7A 2BV5A 3MOWA 2OUDA 5AWXA 1YWFA 3QCGA 3ZM3A 4TVVA 4JMKA 3SMEA 4ZRTA 2QDCA 1XRIA 4J51A
chains in the Genus database with same CATH superfamily
4RI5A 2F6VA 1C85A 2QBQA 2GWOA 5KAAA 3QKPA 2AZRA 2F71A 2I1YA 2CNGA 4JMJA 4ZN5A 2Y68A 3S3HA 2AHSA 2HXPA 4OHDA 4HJQA 3MMJA 4HRFA 5A5EA 1XM2A 2H4VA 5K23A 3D9CA 2AM2A 2CM7A 2HNPA 1XBOA 4MBBA 3GXHA 2CM8A 1JBVA 3D44A 4RI4A 2BIJA 5MMZB 5K9VA 2QDPA 4Y2EA 4Z6BA 3EMUA 2OC3A 1KAKA 1I57A 3AWEA 3NMEA 2ESBA 4KYRA 2H04A 1AAXA 4I8NA 3O4UA 3QCEA 4DGPA 2PT0A 3S3FA 4GE5A 3ZM1A 2NV5A 3QCNA 1G7FA 1G1GA 4AZ1A 2B4SA 1OEUA 1YGUA 1G4WR 1PTVA 2UUOA 3QCHA 1ZZWA 2H4GA 2Y1OA 3PYZA 3V0GA 2P6XA 4BUCA 1G4US 1YTNA 5BUGA 1GQQA 2NZ6A 2I42A 3F41A 1D5RA 4UAGA 2I4GA 5HDEA 3N2AA 5KA0A 2GC5A 3S3EA 1YN9A 2NLKA 4BJOA 3ZM6A 1PH0A 3S3KA 1O5ZA 2X5OA 2R0BA 3QCJA 1BZCA 2H4KA 3QCZA 2CNEA 2QDMA 3MVNA 4BUBA 2CNIA 2PBNA 5K9WA 1OHDA 2M3VA 5I6VA 1RPMA 2JFHA 3SR9A 2J16A 2F70A 2CMCA 3S4EA 1XXPA 2Y2FA 2I6MA 4GFUA 2SHPA 1PA9A 1X24A 1R6HA 1T48A 4QDIA 2H03A 3ZL8A 1YTSA 1OHEA 2CMBA 2QCTA 2WTZA 4IKCA 2QEPA 4RH5A 1Q6TA 1YGRA 2Y67A 1NWEA 3F81A 4R0TA 1MKPA 1YZ4A 3F9AA 3RGQA 2B3OA 2BGEA 4RHGA 5M43A 2G59A 4QAPA 5K22A 1PA1A 1ZC0A 2IMGA 1NNYA 2XPCA 2VTEA 1C87A 2QBPA 1XXVA 3CM3A 1OEOX 4CVLA 1GG4A 4GE6A 5EHRA 4GE2A 2P4DA 1OEMX 1Q6NA 1J4XA 2OZ5A 1JBWA 3UAGA 4D3RA 3O5XA 1C83A 2I75A 4YR8B 2I3UA 1NL9A 1GQYA 3EZZA 2JJDA 2I6PA 2Q05A 3BRHA 2HC2A 1FQ1A 1U26A 2PI7A 2I4EA 3RO1A 1ONZA 4HJPA 2ZN7A 4QUMA 2Y66A 1VHRA 1G1FA 3O3LA 3D1HA 1W7KA 3I36A 1ECVA 2A3KA 3U96A 1A5YA 3D42A 4ZIYA 5KA8A 2CJZA 1SUGA 3ZM2A 3QCIA 3S4OA 3QCDA 5BX1A 3D1OA 4WU2A 2GP0A 2QBRA 1Q6SA 1EEOA 1PTUA 3N0AA 1WCHA 4WTYA 2I4HA 1P3DA 2UUPA 2Y96A 2CNHA 3QKQA 4KYQA 3MOZA 4GRZA 4D3PA 1ZCKA 4OHEA 2FJNA 2ZMMA 3NRSA 5BZXA 3EU0A 2F6ZA 1GWZA 4BPCA 4JNBA 2B49A 4S0GA 5KA2A 4GFVA 2I6IA 2F6FA 2H02A 3RGOA 1ZCLA 2HB1A 5BZZA 4GS0A 1C84A 4H1OA 1YPTA 2VEYA 2F6WA 5IBMA 2F46A 5KABA 1NWLA 1FPZA 1EEHA 4RKKA 3ZM0A 2VTDA 1E0DA 1QZ0A 5KA1A 1J6UA 1BZJA 3A5KA 3V0HA 1WRMA 2E0TA 1PXHA 1GFYA 2VEVA 2GCBA 4C12A 1FGSA 3F9BA 1W78A 3HN7A 5KA4A 4ERCA 2B4OA 4PVGA 1LYVA 3QCMA 5LXQB 3V0IA 1UAGA 1NO6A 2MBCA 1U24A 3F99A 1G1HA 4QF5A 2YDUA 4ICZA 5KA7A 2GCAA 2JFFA 1RXDA 3QCFA 2JFGA 3ZV2A 2I3RA 1PYNA 3OLRA 3ZMQA 1M3GA 4OHHA 2BGDA 4RDDA 2FJMA 1OHCA 1OETA 2XJAA 1QXKA 4GRYA 4QUNA 4OHLA 2HNQA 2B07A 1C88A 2HC1A 5KACA 3I7ZA 1V3AA 2PA5A 1G7GA 2A8BA 2NTAA 2CM3A 1EENA 1LQFA 3GXGA 2QBSA 4CVKA 4YAAA 3BLTA 4Y14A 2VOSA 5KADA 2RF6A 3I80A 2B4UA 2CNFA 2B4PA 1T49A 5A5FA 4ZI4A 1KAVA 2VORA 4NX8A 4D3QA 4NWGA 1C86A 3QCBA 5KA3A 2HY3A 4KI9A 2FH7A 2F00A 2I6OA 5J8RA 2OOQA 4NNDA 5K25A 2F6YA 2VEWA 2HVLA 3QCKA 5EHPA 2F6TA 2VEXA 1Q6MA 1I9TA 2WJPA 4B04A 2GJTA 1T4JA 1PTTA 4R0SA 3V0JA 2PQ5A 3ZMPA 3M4UA 3QCLA 4H34A 4WU3A 2WGPA 3EB1A 4QBEA 2PSZA 3H2XA 1OEVA 4QAHA 5IBSA 4R30A 4OHIA 2I5XA 3BLUA 4JBCA 1NZ7A 1LARA 2NT2A 3O4SA 4C13A 4NYHA 1FPRA 2CM2A 2DXPA 3O4TA 1I9SA 3A5JA 3V0EA 2J16B 3AWFA 3LJ8A 3CWEA 2I6JA 3B7OA 3PS5A 2UAGA 4PYHA 2CMAA 3V0FA 1P15A 2BZLA 1OESA 1Q6JA 1YFOA 5GTJA 2Q47A 4QBWA 4GWFA 3BM8A 4DGXA 5K24A 1L8KA 4WOHA 4CVMA 3RZ2A 5KA9A 2C7SA 4NWFA 1E8CA 2G6ZA 1WAXA 1U25A 1YTWA 3OMHA 1ONYA 4RH9A 2CFVA 2HCMA 2QCJA 3AWGA 3EAXA 1BZHA 1PTYA 3LK7A 1P31A 3ZM5A 1JF7A 3D1QA 3V0DA 1JLNA 2AM1A 3QCCA 1Q1MA 2VEUA 2J17A 1L8GA 4HV4A 1Q6PA 2C46A 2NT7A 2BV5A 3MOWA 2OUDA 5AWXA 1YWFA 3QCGA 3ZM3A 4TVVA 4JMKA 3SMEA 4ZRTA 2QDCA 2GC6A 1XRIA 4J51A
chains in the Genus database with same CATH topology
4RI5A 2F6VA 1C85A 2QBQA 2GWOA 5KAAA 3QKPA 2AZRA 2F71A 2I1YA 2CNGA 4JMJA 4ZN5A 3S3HA 2AHSA 2HXPA 4OHDA 4HJQA 3MMJA 4HRFA 1XM2A 2H4VA 5K23A 3D9CA 2CM7A 2HNPA 1XBOA 4MBBA 3GXHA 2CM8A 3D44A 4RI4A 2BIJA 5MMZB 5K9VA 2QDPA 4Y2EA 4Z6BA 3EMUA 2OC3A 1KAKA 1I57A 3AWEA 3NMEA 2ESBA 4KYRA 2H04A 1AAXA 4I8NA 3O4UA 3QCEA 4DGPA 2PT0A 3S3FA 4GE5A 3ZM1A 2NV5A 3QCNA 1G7FA 1G1GA 4AZ1A 2B4SA 1OEUA 1YGUA 1G4WR 1PTVA 3QCHA 1ZZWA 2H4GA 3V0GA 2P6XA 1G4US 1YTNA 5BUGA 2NZ6A 2I42A 3F41A 1D5RA 2I4GA 5HDEA 5KA0A 3S3EA 1YN9A 2NLKA 4BJOA 1PH0A 3S3KA 2R0BA 3QCJA 1BZCA 2H4KA 2CNEA 2QDMA 2CNIA 2PBNA 5K9WA 1OHDA 2M3VA 5I6VA 1RPMA 3SR9A 2J16A 2F70A 2CMCA 3S4EA 1XXPA 2Y2FA 2I6MA 4GFUA 2SHPA 1PA9A 1X24A 1R6HA 1T48A 2H03A 1YTSA 1OHEA 2CMBA 2QCTA 4IKCA 4RH5A 2QEPA 1Q6TA 1YGRA 1NWEA 3F81A 4R0TA 1MKPA 1YZ4A 3F9AA 3RGQA 2B3OA 2BGEA 4RHGA 5M43A 2G59A 4QAPA 5K22A 1PA1A 1ZC0A 2IMGA 1NNYA 1C87A 2QBPA 1XXVA 3CM3A 1OEOX 4GE6A 5EHRA 4GE2A 2P4DA 1Q6NA 1OEMX 1J4XA 2OZ5A 4D3RA 3O5XA 1C83A 2I75A 4YR8B 2I3UA 1NL9A 3EZZA 2JJDA 2I6PA 2Q05A 3BRHA 2HC2A 1FQ1A 1U26A 2PI7A 2I4EA 3RO1A 1ONZA 4HJPA 2ZN7A 4QUMA 1VHRA 1G1FA 3O3LA 3D1HA 3I36A 1ECVA 2A3KA 3U96A 1A5YA 3D42A 5KA8A 2CJZA 1SUGA 3ZM2A 3QCIA 3S4OA 3QCDA 5BX1A 3D1OA 4WU2A 2GP0A 2QBRA 1Q6SA 1EEOA 3N0AA 1PTUA 1WCHA 4WTYA 2I4HA 3QKQA 2Y96A 2CNHA 4KYQA 3MOZA 4GRZA 4D3PA 1ZCKA 4OHEA 2FJNA 2ZMMA 5BZXA 3EU0A 2F6ZA 1GWZA 4BPCA 4JNBA 2B49A 4S0GA 5KA2A 4GFVA 2I6IA 2F6FA 2H02A 3RGOA 1ZCLA 2HB1A 5BZZA 4GS0A 1C84A 4H1OA 1YPTA 2VEYA 2F6WA 5IBMA 2F46A 5KABA 1NWLA 1FPZA 4RKKA 3ZM0A 5KA1A 1QZ0A 1BZJA 3A5KA 3V0HA 1WRMA 2E0TA 1PXHA 1GFYA 2VEVA 3F9BA 5KA4A 4ERCA 2B4OA 4PVGA 1LYVA 3QCMA 5LXQB 3V0IA 1NO6A 2MBCA 1U24A 3F99A 1G1HA 2YDUA 4ICZA 5KA7A 1RXDA 3QCFA 3ZV2A 2I3RA 1PYNA 3OLRA 3ZMQA 1M3GA 4OHHA 2BGDA 4RDDA 2FJMA 1OHCA 1OETA 1QXKA 4GRYA 4QUNA 4OHLA 2HNQA 2B07A 1C88A 2HC1A 5KACA 3I7ZA 1V3AA 2PA5A 1G7GA 2A8BA 2NTAA 2CM3A 1EENA 1LQFA 3GXGA 2QBSA 4YAAA 3BLTA 4Y14A 5KADA 2RF6A 3I80A 2B4UA 2CNFA 2B4PA 1T49A 4ZI4A 1KAVA 4NX8A 4D3QA 4NWGA 1C86A 3QCBA 5KA3A 2HY3A 4KI9A 2FH7A 2I6OA 5J8RA 2OOQA 4NNDA 5K25A 2F6YA 2VEWA 2HVLA 3QCKA 5EHPA 2F6TA 2VEXA 1Q6MA 1I9TA 4B04A 2GJTA 1T4JA 1PTTA 4R0SA 3V0JA 2PQ5A 3ZMPA 3M4UA 3QCLA 4H34A 4WU3A 2WGPA 3EB1A 4QBEA 2PSZA 3H2XA 1OEVA 4QAHA 5IBSA 4R30A 4OHIA 2I5XA 3BLUA 4JBCA 1NZ7A 1LARA 2NT2A 3O4SA 4NYHA 1FPRA 2CM2A 2DXPA 3O4TA 1I9SA 3A5JA 3V0EA 2J16B 3AWFA 3LJ8A 3CWEA 2I6JA 3B7OA 3PS5A 4PYHA 2CMAA 3V0FA 1P15A 2BZLA 1OESA 1Q6JA 1YFOA 5GTJA 2Q47A 4QBWA 4GWFA 3BM8A 4DGXA 5K24A 1L8KA 4WOHA 3RZ2A 5KA9A 2C7SA 4NWFA 2G6ZA 1WAXA 1U25A 1YTWA 3OMHA 1ONYA 4RH9A 2CFVA 2HCMA 2QCJA 3AWGA 3EAXA 1BZHA 1PTYA 1JF7A 3D1QA 3V0DA 1JLNA 3QCCA 1Q1MA 2VEUA 2J17A 1L8GA 1Q6PA 2C46A 2NT7A 2BV5A 3MOWA 2OUDA 5AWXA 1YWFA 3QCGA 3ZM3A 4TVVA 4JMKA 3SMEA 4ZRTA 2QDCA 1XRIA 4J51A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4RI5 A;  2F6V A;  1C85 A;  2QBQ A;  2GWO A;  5KAA A;  3QKP A;  2AZR A;  2F71 A;  2I1Y A;  2CNG A;  4JMJ A;  4ZN5 A;  3S3H A;  2AHS A;  2HXP A;  4OHD A;  4HJQ A;  3MMJ A;  4HRF A;  1XM2 A;  2H4V A;  5K23 A;  3D9C A;  2CM7 A;  2HNP A;  1XBO A;  4MBB A;  3GXH A;  2CM8 A;  3D44 A;  4RI4 A;  2BIJ A;  5MMZ B;  5K9V A;  2QDP A;  4Y2E A;  4Z6B A;  3EMU A;  2OC3 A;  1KAK A;  1I57 A;  3AWE A;  3NME A;  2ESB A;  4KYR A;  2H04 A;  1AAX A;  4I8N A;  3O4U A;  3QCE A;  4DGP A;  2PT0 A;  3S3F A;  4GE5 A;  3ZM1 A;  2NV5 A;  3QCN A;  1G7F A;  1G1G A;  4AZ1 A;  2B4S A;  1OEU A;  1YGU A;  1G4W R;  1PTV A;  3QCH A;  1ZZW A;  2H4G A;  3V0G A;  2P6X A;  1G4U S;  1YTN A;  5BUG A;  2NZ6 A;  2I42 A;  3F41 A;  1D5R A;  2I4G A;  5HDE A;  5KA0 A;  3S3E A;  1YN9 A;  2NLK A;  4BJO A;  1PH0 A;  3S3K A;  2R0B A;  3QCJ A;  1BZC A;  2H4K A;  2CNE A;  2QDM A;  2CNI A;  2PBN A;  5K9W A;  1OHD A;  2M3V A;  5I6V A;  1RPM A;  3SR9 A;  2J16 A;  2F70 A;  2CMC A;  3S4E A;  1XXP A;  2Y2F A;  2I6M A;  4GFU A;  2SHP A;  1PA9 A;  1X24 A;  1R6H A;  1T48 A;  2H03 A;  1YTS A;  1OHE A;  2CMB A;  2QCT A;  4IKC A;  4RH5 A;  2QEP A;  1Q6T A;  1YGR A;  1NWE A;  3F81 A;  4R0T A;  1MKP A;  1YZ4 A;  3F9A A;  3RGQ A;  2B3O A;  2BGE A;  4RHG A;  5M43 A;  2G59 A;  4QAP A;  5K22 A;  1PA1 A;  1ZC0 A;  2IMG A;  1NNY A;  1C87 A;  2QBP A;  1XXV A;  3CM3 A;  1OEO X;  4GE6 A;  5EHR A;  4GE2 A;  2P4D A;  1Q6N A;  1OEM X;  1J4X A;  2OZ5 A;  4D3R A;  3O5X A;  1C83 A;  2I75 A;  4YR8 B;  2I3U A;  1NL9 A;  3EZZ A;  2JJD A;  2I6P A;  2Q05 A;  3BRH A;  2HC2 A;  1FQ1 A;  1U26 A;  2PI7 A;  2I4E A;  3RO1 A;  1ONZ A;  4HJP A;  2ZN7 A;  4QUM A;  1VHR A;  1G1F A;  3O3L A;  3D1H A;  3I36 A;  1ECV A;  2A3K A;  3U96 A;  1A5Y A;  3D42 A;  5KA8 A;  2CJZ A;  1SUG A;  3ZM2 A;  3QCI A;  3S4O A;  3QCD A;  5BX1 A;  3D1O A;  4WU2 A;  2GP0 A;  2QBR A;  1Q6S A;  1EEO A;  3N0A A;  1PTU A;  1WCH A;  4WTY A;  2I4H A;  3QKQ A;  2Y96 A;  2CNH A;  4KYQ A;  3MOZ A;  4GRZ A;  4D3P A;  1ZCK A;  4OHE A;  2FJN A;  2ZMM A;  5BZX A;  3EU0 A;  2F6Z A;  1GWZ A;  4BPC A;  4JNB A;  2B49 A;  4S0G A;  5KA2 A;  4GFV A;  2I6I A;  2F6F A;  2H02 A;  3RGO A;  1ZCL A;  2HB1 A;  5BZZ A;  4GS0 A;  1C84 A;  4H1O A;  1YPT A;  2VEY A;  2F6W A;  5IBM A;  2F46 A;  5KAB A;  1NWL A;  1FPZ A;  4RKK A;  3ZM0 A;  5KA1 A;  1QZ0 A;  1BZJ A;  3A5K A;  3V0H A;  1WRM A;  2E0T A;  1PXH A;  1GFY A;  2VEV A;  3F9B A;  5KA4 A;  4ERC A;  2B4O A;  4PVG A;  1LYV A;  3QCM A;  5LXQ B;  3V0I A;  1NO6 A;  2MBC A;  1U24 A;  3F99 A;  1G1H A;  2YDU A;  4ICZ A;  5KA7 A;  1RXD A;  3QCF A;  3ZV2 A;  2I3R A;  1PYN A;  3OLR A;  3ZMQ A;  1M3G A;  4OHH A;  2BGD A;  4RDD A;  2FJM A;  1OHC A;  1OET A;  1QXK A;  4GRY A;  4QUN A;  4OHL A;  2HNQ A;  2B07 A;  1C88 A;  2HC1 A;  5KAC A;  3I7Z A;  1V3A A;  2PA5 A;  1G7G A;  2A8B A;  2NTA A;  2CM3 A;  1EEN A;  1LQF A;  3GXG A;  2QBS A;  4YAA A;  3BLT A;  4Y14 A;  5KAD A;  2RF6 A;  3I80 A;  2B4U A;  2CNF A;  2B4P A;  1T49 A;  4ZI4 A;  1KAV A;  4NX8 A;  4D3Q A;  4NWG A;  1C86 A;  3QCB A;  5KA3 A;  2HY3 A;  4KI9 A;  2FH7 A;  2I6O A;  5J8R A;  2OOQ A;  4NND A;  5K25 A;  2F6Y A;  2VEW A;  2HVL A;  3QCK A;  5EHP A;  2F6T A;  2VEX A;  1Q6M A;  1I9T A;  4B04 A;  2GJT A;  1T4J A;  1PTT A;  4R0S A;  3V0J A;  2PQ5 A;  3ZMP A;  3M4U A;  3QCL A;  4H34 A;  4WU3 A;  2WGP A;  3EB1 A;  4QBE A;  2PSZ A;  3H2X A;  1OEV A;  4QAH A;  5IBS A;  4R30 A;  4OHI A;  2I5X A;  3BLU A;  4JBC A;  1NZ7 A;  1LAR A;  2NT2 A;  3O4S A;  4NYH A;  1FPR A;  2CM2 A;  2DXP A;  3O4T A;  1I9S A;  3A5J A;  3V0E A;  2J16 B;  3AWF A;  3LJ8 A;  3CWE A;  2I6J A;  3B7O A;  3PS5 A;  4PYH A;  2CMA A;  3V0F A;  1P15 A;  2BZL A;  1OES A;  1Q6J A;  1YFO A;  5GTJ A;  2Q47 A;  4QBW A;  4GWF A;  3BM8 A;  4DGX A;  5K24 A;  1L8K A;  4WOH A;  3RZ2 A;  5KA9 A;  2C7S A;  4NWF A;  2G6Z A;  1WAX A;  1U25 A;  1YTW A;  3OMH A;  1ONY A;  4RH9 A;  2CFV A;  2HCM A;  2QCJ A;  3AWG A;  3EAX A;  1BZH A;  1PTY A;  1JF7 A;  3D1Q A;  3V0D A;  1JLN A;  3QCC A;  1Q1M A;  2VEU A;  2J17 A;  1L8G A;  1Q6P A;  2C46 A;  2NT7 A;  2BV5 A;  3MOW A;  2OUD A;  5AWX A;  1YWF A;  3QCG A;  3ZM3 A;  4TVV A;  4JMK A;  3SME A;  4ZRT A;  2QDC A;  1XRI A;  4J51 A; 
#chains in the Genus database with same CATH topology
 4RI5 A;  2F6V A;  1C85 A;  2QBQ A;  2GWO A;  5KAA A;  3QKP A;  2AZR A;  2F71 A;  2I1Y A;  2CNG A;  4JMJ A;  4ZN5 A;  2Y68 A;  3S3H A;  2AHS A;  2HXP A;  4OHD A;  4HJQ A;  3MMJ A;  4HRF A;  5A5E A;  1XM2 A;  2H4V A;  5K23 A;  3D9C A;  2AM2 A;  2CM7 A;  2HNP A;  1XBO A;  4MBB A;  3GXH A;  2CM8 A;  1JBV A;  3D44 A;  4RI4 A;  2BIJ A;  5MMZ B;  5K9V A;  2QDP A;  4Y2E A;  4Z6B A;  3EMU A;  2OC3 A;  1KAK A;  1I57 A;  3AWE A;  3NME A;  2ESB A;  4KYR A;  2H04 A;  1AAX A;  4I8N A;  3O4U A;  3QCE A;  4DGP A;  2PT0 A;  3S3F A;  4GE5 A;  3ZM1 A;  2NV5 A;  3QCN A;  1G7F A;  1G1G A;  4AZ1 A;  2B4S A;  1OEU A;  1YGU A;  1G4W R;  1PTV A;  2UUO A;  3QCH A;  1ZZW A;  2H4G A;  2Y1O A;  3PYZ A;  3V0G A;  2P6X A;  4BUC A;  1G4U S;  1YTN A;  5BUG A;  1GQQ A;  2NZ6 A;  2I42 A;  3F41 A;  1D5R A;  4UAG A;  2I4G A;  5HDE A;  3N2A A;  5KA0 A;  2GC5 A;  3S3E A;  1YN9 A;  2NLK A;  4BJO A;  3ZM6 A;  1PH0 A;  3S3K A;  1O5Z A;  2X5O A;  2R0B A;  3QCJ A;  1BZC A;  2H4K A;  3QCZ A;  2CNE A;  2QDM A;  3MVN A;  4BUB A;  2CNI A;  2PBN A;  5K9W A;  1OHD A;  2M3V A;  5I6V A;  1RPM A;  2JFH A;  3SR9 A;  2J16 A;  2F70 A;  2CMC A;  3S4E A;  1XXP A;  2Y2F A;  2I6M A;  4GFU A;  2SHP A;  1PA9 A;  1X24 A;  1R6H A;  1T48 A;  4QDI A;  2H03 A;  3ZL8 A;  1YTS A;  1OHE A;  2CMB A;  2QCT A;  2WTZ A;  4IKC A;  2QEP A;  4RH5 A;  1Q6T A;  1YGR A;  2Y67 A;  1NWE A;  3F81 A;  4R0T A;  1MKP A;  1YZ4 A;  3F9A A;  3RGQ A;  2B3O A;  2BGE A;  4RHG A;  5M43 A;  2G59 A;  4QAP A;  5K22 A;  1PA1 A;  1ZC0 A;  2IMG A;  1NNY A;  2XPC A;  2VTE A;  1C87 A;  2QBP A;  1XXV A;  3CM3 A;  1OEO X;  4CVL A;  1GG4 A;  4GE6 A;  5EHR A;  4GE2 A;  2P4D A;  1OEM X;  1Q6N A;  1J4X A;  2OZ5 A;  1JBW A;  3UAG A;  4D3R A;  3O5X A;  1C83 A;  2I75 A;  4YR8 B;  2I3U A;  1NL9 A;  1GQY A;  3EZZ A;  2JJD A;  2I6P A;  2Q05 A;  3BRH A;  2HC2 A;  1FQ1 A;  1U26 A;  2PI7 A;  2I4E A;  3RO1 A;  1ONZ A;  4HJP A;  2ZN7 A;  4QUM A;  2Y66 A;  1VHR A;  1G1F A;  3O3L A;  3D1H A;  1W7K A;  3I36 A;  1ECV A;  2A3K A;  3U96 A;  1A5Y A;  3D42 A;  4ZIY A;  5KA8 A;  2CJZ A;  1SUG A;  3ZM2 A;  3QCI A;  3S4O A;  3QCD A;  5BX1 A;  3D1O A;  4WU2 A;  2GP0 A;  2QBR A;  1Q6S A;  1EEO A;  1PTU A;  3N0A A;  1WCH A;  4WTY A;  2I4H A;  1P3D A;  2UUP A;  2Y96 A;  2CNH A;  3QKQ A;  4KYQ A;  3MOZ A;  4GRZ A;  4D3P A;  1ZCK A;  4OHE A;  2FJN A;  2ZMM A;  3NRS A;  5BZX A;  3EU0 A;  2F6Z A;  1GWZ A;  4BPC A;  4JNB A;  2B49 A;  4S0G A;  5KA2 A;  4GFV A;  2I6I A;  2F6F A;  2H02 A;  3RGO A;  1ZCL A;  2HB1 A;  5BZZ A;  4GS0 A;  1C84 A;  4H1O A;  1YPT A;  2VEY A;  2F6W A;  5IBM A;  2F46 A;  5KAB A;  1NWL A;  1FPZ A;  1EEH A;  4RKK A;  3ZM0 A;  2VTD A;  1E0D A;  1QZ0 A;  5KA1 A;  1J6U A;  1BZJ A;  3A5K A;  3V0H A;  1WRM A;  2E0T A;  1PXH A;  1GFY A;  2VEV A;  2GCB A;  4C12 A;  1FGS A;  3F9B A;  1W78 A;  3HN7 A;  5KA4 A;  4ERC A;  2B4O A;  4PVG A;  1LYV A;  3QCM A;  5LXQ B;  3V0I A;  1UAG A;  1NO6 A;  2MBC A;  1U24 A;  3F99 A;  1G1H A;  4QF5 A;  2YDU A;  4ICZ A;  5KA7 A;  2GCA A;  2JFF A;  1RXD A;  3QCF A;  2JFG A;  3ZV2 A;  2I3R A;  1PYN A;  3OLR A;  3ZMQ A;  1M3G A;  4OHH A;  2BGD A;  4RDD A;  2FJM A;  1OHC A;  1OET A;  2XJA A;  1QXK A;  4GRY A;  4QUN A;  4OHL A;  2HNQ A;  2B07 A;  1C88 A;  2HC1 A;  5KAC A;  3I7Z A;  1V3A A;  2PA5 A;  1G7G A;  2A8B A;  2NTA A;  2CM3 A;  1EEN A;  1LQF A;  3GXG A;  2QBS A;  4CVK A;  4YAA A;  3BLT A;  4Y14 A;  2VOS A;  5KAD A;  2RF6 A;  3I80 A;  2B4U A;  2CNF A;  2B4P A;  1T49 A;  5A5F A;  4ZI4 A;  1KAV A;  2VOR A;  4NX8 A;  4D3Q A;  4NWG A;  1C86 A;  3QCB A;  5KA3 A;  2HY3 A;  4KI9 A;  2FH7 A;  2F00 A;  2I6O A;  5J8R A;  2OOQ A;  4NND A;  5K25 A;  2F6Y A;  2VEW A;  2HVL A;  3QCK A;  5EHP A;  2F6T A;  2VEX A;  1Q6M A;  1I9T A;  2WJP A;  4B04 A;  2GJT A;  1T4J A;  1PTT A;  4R0S A;  3V0J A;  2PQ5 A;  3ZMP A;  3M4U A;  3QCL A;  4H34 A;  4WU3 A;  2WGP A;  3EB1 A;  4QBE A;  2PSZ A;  3H2X A;  1OEV A;  4QAH A;  5IBS A;  4R30 A;  4OHI A;  2I5X A;  3BLU A;  4JBC A;  1NZ7 A;  1LAR A;  2NT2 A;  3O4S A;  4C13 A;  4NYH A;  1FPR A;  2CM2 A;  2DXP A;  3O4T A;  1I9S A;  3A5J A;  3V0E A;  2J16 B;  3AWF A;  3LJ8 A;  3CWE A;  2I6J A;  3B7O A;  3PS5 A;  2UAG A;  4PYH A;  2CMA A;  3V0F A;  1P15 A;  2BZL A;  1OES A;  1Q6J A;  1YFO A;  5GTJ A;  2Q47 A;  4QBW A;  4GWF A;  3BM8 A;  4DGX A;  5K24 A;  1L8K A;  4WOH A;  4CVM A;  3RZ2 A;  5KA9 A;  2C7S A;  4NWF A;  1E8C A;  2G6Z A;  1WAX A;  1U25 A;  1YTW A;  3OMH A;  1ONY A;  4RH9 A;  2CFV A;  2HCM A;  2QCJ A;  3AWG A;  3EAX A;  1BZH A;  1PTY A;  3LK7 A;  1P31 A;  3ZM5 A;  1JF7 A;  3D1Q A;  3V0D A;  1JLN A;  2AM1 A;  3QCC A;  1Q1M A;  2VEU A;  2J17 A;  1L8G A;  4HV4 A;  1Q6P A;  2C46 A;  2NT7 A;  2BV5 A;  3MOW A;  2OUD A;  5AWX A;  1YWF A;  3QCG A;  3ZM3 A;  4TVV A;  4JMK A;  3SME A;  4ZRT A;  2QDC A;  2GC6 A;  1XRI A;  4J51 A; 
#chains in the Genus database with same CATH homology
 4RI5 A;  2F6V A;  1C85 A;  2QBQ A;  2GWO A;  5KAA A;  3QKP A;  2AZR A;  2F71 A;  2I1Y A;  2CNG A;  4JMJ A;  4ZN5 A;  3S3H A;  2AHS A;  2HXP A;  4OHD A;  4HJQ A;  3MMJ A;  4HRF A;  1XM2 A;  2H4V A;  5K23 A;  3D9C A;  2CM7 A;  2HNP A;  1XBO A;  4MBB A;  3GXH A;  2CM8 A;  3D44 A;  4RI4 A;  2BIJ A;  5MMZ B;  5K9V A;  2QDP A;  4Y2E A;  4Z6B A;  3EMU A;  2OC3 A;  1KAK A;  1I57 A;  3AWE A;  3NME A;  2ESB A;  4KYR A;  2H04 A;  1AAX A;  4I8N A;  3O4U A;  3QCE A;  4DGP A;  2PT0 A;  3S3F A;  4GE5 A;  3ZM1 A;  2NV5 A;  3QCN A;  1G7F A;  1G1G A;  4AZ1 A;  2B4S A;  1OEU A;  1YGU A;  1G4W R;  1PTV A;  3QCH A;  1ZZW A;  2H4G A;  3V0G A;  2P6X A;  1G4U S;  1YTN A;  5BUG A;  2NZ6 A;  2I42 A;  3F41 A;  1D5R A;  2I4G A;  5HDE A;  5KA0 A;  3S3E A;  1YN9 A;  2NLK A;  4BJO A;  1PH0 A;  3S3K A;  2R0B A;  3QCJ A;  1BZC A;  2H4K A;  2CNE A;  2QDM A;  2CNI A;  2PBN A;  5K9W A;  1OHD A;  2M3V A;  5I6V A;  1RPM A;  3SR9 A;  2J16 A;  2F70 A;  2CMC A;  3S4E A;  1XXP A;  2Y2F A;  2I6M A;  4GFU A;  2SHP A;  1PA9 A;  1X24 A;  1R6H A;  1T48 A;  2H03 A;  1YTS A;  1OHE A;  2CMB A;  2QCT A;  4IKC A;  4RH5 A;  2QEP A;  1Q6T A;  1YGR A;  1NWE A;  3F81 A;  4R0T A;  1MKP A;  1YZ4 A;  3F9A A;  3RGQ A;  2B3O A;  2BGE A;  4RHG A;  5M43 A;  2G59 A;  4QAP A;  5K22 A;  1PA1 A;  1ZC0 A;  2IMG A;  1NNY A;  1C87 A;  2QBP A;  1XXV A;  3CM3 A;  1OEO X;  4GE6 A;  5EHR A;  4GE2 A;  2P4D A;  1Q6N A;  1OEM X;  1J4X A;  2OZ5 A;  4D3R A;  3O5X A;  1C83 A;  2I75 A;  4YR8 B;  2I3U A;  1NL9 A;  3EZZ A;  2JJD A;  2I6P A;  2Q05 A;  3BRH A;  2HC2 A;  1FQ1 A;  1U26 A;  2PI7 A;  2I4E A;  3RO1 A;  1ONZ A;  4HJP A;  2ZN7 A;  4QUM A;  1VHR A;  1G1F A;  3O3L A;  3D1H A;  3I36 A;  1ECV A;  2A3K A;  3U96 A;  1A5Y A;  3D42 A;  5KA8 A;  2CJZ A;  1SUG A;  3ZM2 A;  3QCI A;  3S4O A;  3QCD A;  5BX1 A;  3D1O A;  4WU2 A;  2GP0 A;  2QBR A;  1Q6S A;  1EEO A;  3N0A A;  1PTU A;  1WCH A;  4WTY A;  2I4H A;  3QKQ A;  2Y96 A;  2CNH A;  4KYQ A;  3MOZ A;  4GRZ A;  4D3P A;  1ZCK A;  4OHE A;  2FJN A;  2ZMM A;  5BZX A;  3EU0 A;  2F6Z A;  1GWZ A;  4BPC A;  4JNB A;  2B49 A;  4S0G A;  5KA2 A;  4GFV A;  2I6I A;  2F6F A;  2H02 A;  3RGO A;  1ZCL A;  2HB1 A;  5BZZ A;  4GS0 A;  1C84 A;  4H1O A;  1YPT A;  2VEY A;  2F6W A;  5IBM A;  2F46 A;  5KAB A;  1NWL A;  1FPZ A;  4RKK A;  3ZM0 A;  5KA1 A;  1QZ0 A;  1BZJ A;  3A5K A;  3V0H A;  1WRM A;  2E0T A;  1PXH A;  1GFY A;  2VEV A;  3F9B A;  5KA4 A;  4ERC A;  2B4O A;  4PVG A;  1LYV A;  3QCM A;  5LXQ B;  3V0I A;  1NO6 A;  2MBC A;  1U24 A;  3F99 A;  1G1H A;  2YDU A;  4ICZ A;  5KA7 A;  1RXD A;  3QCF A;  3ZV2 A;  2I3R A;  1PYN A;  3OLR A;  3ZMQ A;  1M3G A;  4OHH A;  2BGD A;  4RDD A;  2FJM A;  1OHC A;  1OET A;  1QXK A;  4GRY A;  4QUN A;  4OHL A;  2HNQ A;  2B07 A;  1C88 A;  2HC1 A;  5KAC A;  3I7Z A;  1V3A A;  2PA5 A;  1G7G A;  2A8B A;  2NTA A;  2CM3 A;  1EEN A;  1LQF A;  3GXG A;  2QBS A;  4YAA A;  3BLT A;  4Y14 A;  5KAD A;  2RF6 A;  3I80 A;  2B4U A;  2CNF A;  2B4P A;  1T49 A;  4ZI4 A;  1KAV A;  4NX8 A;  4D3Q A;  4NWG A;  1C86 A;  3QCB A;  5KA3 A;  2HY3 A;  4KI9 A;  2FH7 A;  2I6O A;  5J8R A;  2OOQ A;  4NND A;  5K25 A;  2F6Y A;  2VEW A;  2HVL A;  3QCK A;  5EHP A;  2F6T A;  2VEX A;  1Q6M A;  1I9T A;  4B04 A;  2GJT A;  1T4J A;  1PTT A;  4R0S A;  3V0J A;  2PQ5 A;  3ZMP A;  3M4U A;  3QCL A;  4H34 A;  4WU3 A;  2WGP A;  3EB1 A;  4QBE A;  2PSZ A;  3H2X A;  1OEV A;  4QAH A;  5IBS A;  4R30 A;  4OHI A;  2I5X A;  3BLU A;  4JBC A;  1NZ7 A;  1LAR A;  2NT2 A;  3O4S A;  4NYH A;  1FPR A;  2CM2 A;  2DXP A;  3O4T A;  1I9S A;  3A5J A;  3V0E A;  2J16 B;  3AWF A;  3LJ8 A;  3CWE A;  2I6J A;  3B7O A;  3PS5 A;  4PYH A;  2CMA A;  3V0F A;  1P15 A;  2BZL A;  1OES A;  1Q6J A;  1YFO A;  5GTJ A;  2Q47 A;  4QBW A;  4GWF A;  3BM8 A;  4DGX A;  5K24 A;  1L8K A;  4WOH A;  3RZ2 A;  5KA9 A;  2C7S A;  4NWF A;  2G6Z A;  1WAX A;  1U25 A;  1YTW A;  3OMH A;  1ONY A;  4RH9 A;  2CFV A;  2HCM A;  2QCJ A;  3AWG A;  3EAX A;  1BZH A;  1PTY A;  1JF7 A;  3D1Q A;  3V0D A;  1JLN A;  3QCC A;  1Q1M A;  2VEU A;  2J17 A;  1L8G A;  1Q6P A;  2C46 A;  2NT7 A;  2BV5 A;  3MOW A;  2OUD A;  5AWX A;  1YWF A;  3QCG A;  3ZM3 A;  4TVV A;  4JMK A;  3SME A;  4ZRT A;  2QDC A;  1XRI A;  4J51 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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