3C7KB

Molecular architecture of galphao and the structural basis for rgs16-mediated deactivation
Total Genus 39
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
39
sequence length
120
structure length
119
Chain Sequence
VLGWRSFDLLLNSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHHIFDEYIRSEAPKEVNIDHETRELTKTNLQAATTSCFDVAQGKTRTLMEKDSYPRFLKSPAYR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Signaling protein
molecule keywords Guanine nucleotide-binding protein G(o) subunit alpha
publication title Molecular architecture of G{alpha}o and the structural basis for RGS16-mediated deactivation.
pubmed doi rcsb
source organism Mus musculus
total genus 39
structure length 119
sequence length 120
chains with identical sequence D
ec nomenclature
pdb deposition date 2008-02-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 3c7kB02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 3c7kB01
1EMUA 2OJ4A 3PVUA 2D9JA 5DO9B 2BT2A 2GTPC 4MK0A 1DK8A 5HE3A 1FQKB 4TNDA 4TNBA 2ODEB 2DLVA 3C7LA 4PNKA 2OWIA 1EZYA 3UZTA 3C7KB 3PVWA 3PSCA 2AF0A 3KRWA 4EKDB 5HE1A 3KRXA 2CRPA 1CMZA 5HE2A 2JNUA 3CIKA 2EBZA 1OMWA 3NYNA 2BCJA 2JM5A 2V4ZB 1EZTA 2IHDA 3NYOA 2IK8B 5HE0A 1AGRE 2IHBB 1FQJB 3V5WA 2BV1A 1FQIA
chains in the Genus database with same CATH superfamily
1EMUA 2OJ4A 3PVUA 2D9JA 5DO9B 2BT2A 2GTPC 4MK0A 1DK8A 5HE3A 1FQKB 4TNDA 4TNBA 2ODEB 2DLVA 3C7LA 4PNKA 2OWIA 1EZYA 3UZTA 3C7KB 3QYFA 3PVWA 3PSCA 2AF0A 3KRWA 4EKDB 5HE1A 3KRXA 5REQB 2CRPA 1CMZA 5HE2A 2JNUA 3CIKA 2EBZA 1OMWA 3NYNA 2BCJA 2JM5A 3I5QA 4HTEA 2V4ZB 1EZTA 2IHDA 3NYOA 2IK8B 5HE0A 1AGRE 2IHBB 1FQJB 3V5WA 2BV1A 1FQIA
chains in the Genus database with same CATH topology
1EMUA 2OJ4A 3PVUA 2D9JA 5DO9B 2BT2A 2GTPC 4MK0A 1DK8A 5HE3A 1FQKB 4TNDA 4TNBA 2ODEB 2DLVA 3C7LA 4PNKA 2OWIA 1EZYA 3UZTA 3C7KB 3QYFA 3PVWA 3PSCA 2AF0A 3KRWA 4EKDB 5HE1A 3KRXA 5REQB 2CRPA 1CMZA 5HE2A 2JNUA 3CIKA 2EBZA 1OMWA 3NYNA 2BCJA 2JM5A 2V4ZB 1EZTA 2IHDA 3NYOA 2IK8B 5HE0A 1AGRE 2IHBB 1FQJB 3V5WA 2BV1A 1FQIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1EMU A;  2OJ4 A;  3PVU A;  2D9J A;  5DO9 B;  2BT2 A;  2GTP C;  4MK0 A;  1DK8 A;  5HE3 A;  1FQK B;  4TND A;  4TNB A;  2ODE B;  2DLV A;  3C7L A;  4PNK A;  2OWI A;  1EZY A;  3UZT A;  3C7K B;  3PVW A;  3PSC A;  2AF0 A;  3KRW A;  4EKD B;  5HE1 A;  3KRX A;  2CRP A;  1CMZ A;  5HE2 A;  2JNU A;  3CIK A;  2EBZ A;  1OMW A;  3NYN A;  2BCJ A;  2JM5 A;  2V4Z B;  1EZT A;  2IHD A;  3NYO A;  2IK8 B;  5HE0 A;  1AGR E;  2IHB B;  1FQJ B;  3V5W A;  2BV1 A;  1FQI A; 
#chains in the Genus database with same CATH topology
 1EMU A;  2OJ4 A;  3PVU A;  2D9J A;  5DO9 B;  2BT2 A;  2GTP C;  4MK0 A;  1DK8 A;  5HE3 A;  1FQK B;  4TND A;  4TNB A;  2ODE B;  2DLV A;  3C7L A;  4PNK A;  2OWI A;  1EZY A;  3UZT A;  3C7K B;  3QYF A;  3PVW A;  3PSC A;  2AF0 A;  3KRW A;  4EKD B;  5HE1 A;  3KRX A;  5REQ B;  2CRP A;  1CMZ A;  5HE2 A;  2JNU A;  3CIK A;  2EBZ A;  1OMW A;  3NYN A;  2BCJ A;  2JM5 A;  3I5Q A;  4HTE A;  2V4Z B;  1EZT A;  2IHD A;  3NYO A;  2IK8 B;  5HE0 A;  1AGR E;  2IHB B;  1FQJ B;  3V5W A;  2BV1 A;  1FQI A; 
#chains in the Genus database with same CATH homology
 1EMU A;  2OJ4 A;  3PVU A;  2D9J A;  5DO9 B;  2BT2 A;  2GTP C;  4MK0 A;  1DK8 A;  5HE3 A;  1FQK B;  4TND A;  4TNB A;  2ODE B;  2DLV A;  3C7L A;  4PNK A;  2OWI A;  1EZY A;  3UZT A;  3C7K B;  3QYF A;  3PVW A;  3PSC A;  2AF0 A;  3KRW A;  4EKD B;  5HE1 A;  3KRX A;  5REQ B;  2CRP A;  1CMZ A;  5HE2 A;  2JNU A;  3CIK A;  2EBZ A;  1OMW A;  3NYN A;  2BCJ A;  2JM5 A;  2V4Z B;  1EZT A;  2IHD A;  3NYO A;  2IK8 B;  5HE0 A;  1AGR E;  2IHB B;  1FQJ B;  3V5W A;  2BV1 A;  1FQI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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