3C7KB

Molecular architecture of galphao and the structural basis for rgs16-mediated deactivation
Total Genus 39
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
39
sequence length
120
structure length
119
Chain Sequence
VLGWRSFDLLLNSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHHIFDEYIRSEAPKEVNIDHETRELTKTNLQAATTSCFDVAQGKTRTLMEKDSYPRFLKSPAYR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular architecture of G{alpha}o and the structural basis for RGS16-mediated deactivation.
pubmed doi rcsb
molecule tags Signaling protein
source organism Mus musculus
molecule keywords Guanine nucleotide-binding protein G(o) subunit alpha
total genus 39
structure length 119
sequence length 120
chains with identical sequence D
ec nomenclature
pdb deposition date 2008-02-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 3c7kB02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 3c7kB01
3KRXA 1FQKB 3KRWA 4EKDB 1FQJB 2OJ4A 2BT2A 1AGRE 2AF0A 3UZTA 2DLVA 2BV1A 3C7KB 2IK8B 5HE3A 2V4ZB 3PVWA 3PVUA 4PNKA 1EZTA 4TNBA 2IHDA 3V5WA 4TNDA 2IHBB 3NYOA 3NYNA 1EMUA 2CRPA 3CIKA 1OMWA 2BCJA 1EZYA 2ODEB 1FQIA 3PSCA 3C7LA 2D9JA 5HE2A 5DO9B 2EBZA 4MK0A 5HE1A 5HE0A 2GTPC 2JNUA 2OWIA 1DK8A 1CMZA 2JM5A
chains in the Genus database with same CATH superfamily
3KRXA 1FQKB 3KRWA 4EKDB 1FQJB 2OJ4A 2BT2A 1AGRE 2AF0A 4HTEA 3UZTA 2DLVA 2BV1A 3QYFA 3C7KB 2IK8B 5HE3A 2V4ZB 3PVWA 3PVUA 4PNKA 1EZTA 4TNBA 2IHDA 3V5WA 4TNDA 2IHBB 3NYOA 3NYNA 1EMUA 2CRPA 3CIKA 1OMWA 2BCJA 1EZYA 2ODEB 1FQIA 3PSCA 3C7LA 2D9JA 5HE2A 5DO9B 2EBZA 4MK0A 5HE1A 5HE0A 2GTPC 3I5QA 5REQB 2JNUA 2OWIA 1DK8A 1CMZA 2JM5A
chains in the Genus database with same CATH topology
3KRXA 1FQKB 3KRWA 4EKDB 1FQJB 2OJ4A 2BT2A 1AGRE 2AF0A 3UZTA 2DLVA 2BV1A 3QYFA 3C7KB 2IK8B 5HE3A 2V4ZB 3PVWA 3PVUA 4PNKA 1EZTA 4TNBA 2IHDA 3V5WA 4TNDA 2IHBB 3NYOA 3NYNA 1EMUA 2CRPA 3CIKA 1OMWA 2BCJA 1EZYA 2ODEB 1FQIA 3PSCA 3C7LA 2D9JA 5HE2A 5DO9B 2EBZA 4MK0A 5HE1A 5HE0A 2GTPC 5REQB 2JNUA 2OWIA 1DK8A 1CMZA 2JM5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KRX A;  1FQK B;  3KRW A;  4EKD B;  1FQJ B;  2OJ4 A;  2BT2 A;  1AGR E;  2AF0 A;  3UZT A;  2DLV A;  2BV1 A;  3C7K B;  2IK8 B;  5HE3 A;  2V4Z B;  3PVW A;  3PVU A;  4PNK A;  1EZT A;  4TNB A;  2IHD A;  3V5W A;  4TND A;  2IHB B;  3NYO A;  3NYN A;  1EMU A;  2CRP A;  3CIK A;  1OMW A;  2BCJ A;  1EZY A;  2ODE B;  1FQI A;  3PSC A;  3C7L A;  2D9J A;  5HE2 A;  5DO9 B;  2EBZ A;  4MK0 A;  5HE1 A;  5HE0 A;  2GTP C;  2JNU A;  2OWI A;  1DK8 A;  1CMZ A;  2JM5 A; 
#chains in the Genus database with same CATH topology
 3KRX A;  1FQK B;  3KRW A;  4EKD B;  1FQJ B;  2OJ4 A;  2BT2 A;  1AGR E;  2AF0 A;  4HTE A;  3UZT A;  2DLV A;  2BV1 A;  3QYF A;  3C7K B;  2IK8 B;  5HE3 A;  2V4Z B;  3PVW A;  3PVU A;  4PNK A;  1EZT A;  4TNB A;  2IHD A;  3V5W A;  4TND A;  2IHB B;  3NYO A;  3NYN A;  1EMU A;  2CRP A;  3CIK A;  1OMW A;  2BCJ A;  1EZY A;  2ODE B;  1FQI A;  3PSC A;  3C7L A;  2D9J A;  5HE2 A;  5DO9 B;  2EBZ A;  4MK0 A;  5HE1 A;  5HE0 A;  2GTP C;  3I5Q A;  5REQ B;  2JNU A;  2OWI A;  1DK8 A;  1CMZ A;  2JM5 A; 
#chains in the Genus database with same CATH homology
 3KRX A;  1FQK B;  3KRW A;  4EKD B;  1FQJ B;  2OJ4 A;  2BT2 A;  1AGR E;  2AF0 A;  3UZT A;  2DLV A;  2BV1 A;  3QYF A;  3C7K B;  2IK8 B;  5HE3 A;  2V4Z B;  3PVW A;  3PVU A;  4PNK A;  1EZT A;  4TNB A;  2IHD A;  3V5W A;  4TND A;  2IHB B;  3NYO A;  3NYN A;  1EMU A;  2CRP A;  3CIK A;  1OMW A;  2BCJ A;  1EZY A;  2ODE B;  1FQI A;  3PSC A;  3C7L A;  2D9J A;  5HE2 A;  5DO9 B;  2EBZ A;  4MK0 A;  5HE1 A;  5HE0 A;  2GTP C;  5REQ B;  2JNU A;  2OWI A;  1DK8 A;  1CMZ A;  2JM5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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