3C7LA

Molecular architecture of galphao and the structural basis for rgs16-mediated deactivation
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
124
structure length
124
Chain Sequence
DVLGWRESFDLLLNSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHHIFDEYIRSEAPKEVNIDHETRELTKTNLQAATTSCFDVAQGKTRTLMEKDSYPRFLKSPAYRDLA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Signaling protein
molecule keywords Regulator of G-protein signaling 16
publication title Molecular architecture of G{alpha}o and the structural basis for RGS16-mediated deactivation.
pubmed doi rcsb
source organism Mus musculus
total genus 50
structure length 124
sequence length 124
chains with identical sequence B
ec nomenclature
pdb deposition date 2008-02-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 3c7lA02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 3c7lA01
2BT2A 5HE3A 3C7KB 3PVWA 1FQJB 2CRPA 3UZTA 3V5WA 2AF0A 2OWIA 1FQKB 2JNUA 2IK8B 2ODEB 3NYOA 5HE2A 3PSCA 2EBZA 1OMWA 1EZTA 3CIKA 3NYNA 4TNBA 3C7LA 3KRXA 4EKDB 2BCJA 2JM5A 2DLVA 3KRWA 4MK0A 1DK8A 4TNDA 2IHBB 2D9JA 1EMUA 4PNKA 1EZYA 2GTPC 5HE1A 2V4ZB 1AGRE 1FQIA 2IHDA 3PVUA 1CMZA 2OJ4A 5HE0A 5DO9B 2BV1A
chains in the Genus database with same CATH superfamily
2BT2A 5HE3A 3C7KB 3PVWA 1FQJB 2CRPA 3UZTA 3V5WA 2AF0A 2OWIA 1FQKB 2JNUA 2IK8B 2ODEB 3NYOA 5HE2A 3PSCA 3QYFA 2EBZA 1OMWA 1EZTA 3CIKA 3NYNA 4TNBA 3C7LA 3KRXA 4EKDB 2BCJA 2JM5A 2DLVA 3KRWA 4MK0A 1DK8A 4TNDA 2IHBB 2D9JA 1EMUA 4PNKA 1EZYA 5REQB 2GTPC 5HE1A 2V4ZB 1AGRE 1FQIA 2IHDA 3I5QA 3PVUA 1CMZA 2OJ4A 4HTEA 5HE0A 5DO9B 2BV1A
chains in the Genus database with same CATH topology
2BT2A 5HE3A 3C7KB 3PVWA 1FQJB 2CRPA 3UZTA 3V5WA 2AF0A 2OWIA 1FQKB 2JNUA 2IK8B 2ODEB 3NYOA 5HE2A 3PSCA 3QYFA 2EBZA 1OMWA 1EZTA 3CIKA 3NYNA 4TNBA 3C7LA 3KRXA 4EKDB 2BCJA 2JM5A 2DLVA 3KRWA 4MK0A 1DK8A 4TNDA 2IHBB 2D9JA 1EMUA 4PNKA 1EZYA 5REQB 2GTPC 5HE1A 2V4ZB 1AGRE 1FQIA 2IHDA 3PVUA 1CMZA 2OJ4A 5HE0A 5DO9B 2BV1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BT2 A;  5HE3 A;  3C7K B;  3PVW A;  1FQJ B;  2CRP A;  3UZT A;  3V5W A;  2AF0 A;  2OWI A;  1FQK B;  2JNU A;  2IK8 B;  2ODE B;  3NYO A;  5HE2 A;  3PSC A;  2EBZ A;  1OMW A;  1EZT A;  3CIK A;  3NYN A;  4TNB A;  3C7L A;  3KRX A;  4EKD B;  2BCJ A;  2JM5 A;  2DLV A;  3KRW A;  4MK0 A;  1DK8 A;  4TND A;  2IHB B;  2D9J A;  1EMU A;  4PNK A;  1EZY A;  2GTP C;  5HE1 A;  2V4Z B;  1AGR E;  1FQI A;  2IHD A;  3PVU A;  1CMZ A;  2OJ4 A;  5HE0 A;  5DO9 B;  2BV1 A; 
#chains in the Genus database with same CATH topology
 2BT2 A;  5HE3 A;  3C7K B;  3PVW A;  1FQJ B;  2CRP A;  3UZT A;  3V5W A;  2AF0 A;  2OWI A;  1FQK B;  2JNU A;  2IK8 B;  2ODE B;  3NYO A;  5HE2 A;  3PSC A;  3QYF A;  2EBZ A;  1OMW A;  1EZT A;  3CIK A;  3NYN A;  4TNB A;  3C7L A;  3KRX A;  4EKD B;  2BCJ A;  2JM5 A;  2DLV A;  3KRW A;  4MK0 A;  1DK8 A;  4TND A;  2IHB B;  2D9J A;  1EMU A;  4PNK A;  1EZY A;  5REQ B;  2GTP C;  5HE1 A;  2V4Z B;  1AGR E;  1FQI A;  2IHD A;  3I5Q A;  3PVU A;  1CMZ A;  2OJ4 A;  4HTE A;  5HE0 A;  5DO9 B;  2BV1 A; 
#chains in the Genus database with same CATH homology
 2BT2 A;  5HE3 A;  3C7K B;  3PVW A;  1FQJ B;  2CRP A;  3UZT A;  3V5W A;  2AF0 A;  2OWI A;  1FQK B;  2JNU A;  2IK8 B;  2ODE B;  3NYO A;  5HE2 A;  3PSC A;  3QYF A;  2EBZ A;  1OMW A;  1EZT A;  3CIK A;  3NYN A;  4TNB A;  3C7L A;  3KRX A;  4EKD B;  2BCJ A;  2JM5 A;  2DLV A;  3KRW A;  4MK0 A;  1DK8 A;  4TND A;  2IHB B;  2D9J A;  1EMU A;  4PNK A;  1EZY A;  5REQ B;  2GTP C;  5HE1 A;  2V4Z B;  1AGR E;  1FQI A;  2IHD A;  3PVU A;  1CMZ A;  2OJ4 A;  5HE0 A;  5DO9 B;  2BV1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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