3C7LA

Molecular architecture of galphao and the structural basis for rgs16-mediated deactivation
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
124
structure length
124
Chain Sequence
DVLGWRESFDLLLNSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHHIFDEYIRSEAPKEVNIDHETRELTKTNLQAATTSCFDVAQGKTRTLMEKDSYPRFLKSPAYRDLA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular architecture of G{alpha}o and the structural basis for RGS16-mediated deactivation.
pubmed doi rcsb
molecule tags Signaling protein
source organism Mus musculus
molecule keywords Regulator of G-protein signaling 16
total genus 50
structure length 124
sequence length 124
chains with identical sequence B
ec nomenclature
pdb deposition date 2008-02-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 3c7lA02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 3c7lA01
1FQKB 3PVUA 2JNUA 3KRXA 1EMUA 1FQIA 4TNDA 2GTPC 2OWIA 3PSCA 2BT2A 2ODEB 3C7KB 2IHDA 5HE0A 2EBZA 1AGRE 2IK8B 3KRWA 4TNBA 5DO9B 5HE3A 1OMWA 2JM5A 2OJ4A 1EZTA 4PNKA 1FQJB 3UZTA 2IHBB 3NYOA 3V5WA 2BV1A 2V4ZB 1DK8A 3PVWA 5HE2A 3C7LA 4MK0A 2CRPA 2DLVA 2AF0A 1CMZA 2BCJA 1EZYA 5HE1A 4EKDB 3NYNA 2D9JA 3CIKA
chains in the Genus database with same CATH superfamily
1FQKB 3PVUA 2JNUA 3KRXA 1EMUA 1FQIA 4TNDA 2GTPC 2OWIA 5REQB 3PSCA 2BT2A 2ODEB 3C7KB 2IHDA 5HE0A 2EBZA 1AGRE 2IK8B 3KRWA 4TNBA 5DO9B 5HE3A 1OMWA 2JM5A 2OJ4A 1EZTA 4PNKA 1FQJB 3UZTA 2IHBB 3NYOA 3V5WA 2BV1A 2V4ZB 1DK8A 3PVWA 5HE2A 3C7LA 3I5QA 4HTEA 4MK0A 2CRPA 2DLVA 2AF0A 1CMZA 3QYFA 2BCJA 1EZYA 5HE1A 4EKDB 3NYNA 2D9JA 3CIKA
chains in the Genus database with same CATH topology
1FQKB 3PVUA 2JNUA 3KRXA 1EMUA 1FQIA 4TNDA 2GTPC 2OWIA 5REQB 3PSCA 2BT2A 2ODEB 3C7KB 2IHDA 5HE0A 2EBZA 1AGRE 2IK8B 3KRWA 4TNBA 5DO9B 5HE3A 1OMWA 2JM5A 2OJ4A 1EZTA 4PNKA 1FQJB 3UZTA 2IHBB 3NYOA 3V5WA 2BV1A 2V4ZB 1DK8A 3PVWA 5HE2A 3C7LA 4MK0A 2CRPA 2DLVA 2AF0A 1CMZA 3QYFA 2BCJA 1EZYA 5HE1A 4EKDB 3NYNA 2D9JA 3CIKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1FQK B;  3PVU A;  2JNU A;  3KRX A;  1EMU A;  1FQI A;  4TND A;  2GTP C;  2OWI A;  3PSC A;  2BT2 A;  2ODE B;  3C7K B;  2IHD A;  5HE0 A;  2EBZ A;  1AGR E;  2IK8 B;  3KRW A;  4TNB A;  5DO9 B;  5HE3 A;  1OMW A;  2JM5 A;  2OJ4 A;  1EZT A;  4PNK A;  1FQJ B;  3UZT A;  2IHB B;  3NYO A;  3V5W A;  2BV1 A;  2V4Z B;  1DK8 A;  3PVW A;  5HE2 A;  3C7L A;  4MK0 A;  2CRP A;  2DLV A;  2AF0 A;  1CMZ A;  2BCJ A;  1EZY A;  5HE1 A;  4EKD B;  3NYN A;  2D9J A;  3CIK A; 
#chains in the Genus database with same CATH topology
 1FQK B;  3PVU A;  2JNU A;  3KRX A;  1EMU A;  1FQI A;  4TND A;  2GTP C;  2OWI A;  5REQ B;  3PSC A;  2BT2 A;  2ODE B;  3C7K B;  2IHD A;  5HE0 A;  2EBZ A;  1AGR E;  2IK8 B;  3KRW A;  4TNB A;  5DO9 B;  5HE3 A;  1OMW A;  2JM5 A;  2OJ4 A;  1EZT A;  4PNK A;  1FQJ B;  3UZT A;  2IHB B;  3NYO A;  3V5W A;  2BV1 A;  2V4Z B;  1DK8 A;  3PVW A;  5HE2 A;  3C7L A;  3I5Q A;  4HTE A;  4MK0 A;  2CRP A;  2DLV A;  2AF0 A;  1CMZ A;  3QYF A;  2BCJ A;  1EZY A;  5HE1 A;  4EKD B;  3NYN A;  2D9J A;  3CIK A; 
#chains in the Genus database with same CATH homology
 1FQK B;  3PVU A;  2JNU A;  3KRX A;  1EMU A;  1FQI A;  4TND A;  2GTP C;  2OWI A;  5REQ B;  3PSC A;  2BT2 A;  2ODE B;  3C7K B;  2IHD A;  5HE0 A;  2EBZ A;  1AGR E;  2IK8 B;  3KRW A;  4TNB A;  5DO9 B;  5HE3 A;  1OMW A;  2JM5 A;  2OJ4 A;  1EZT A;  4PNK A;  1FQJ B;  3UZT A;  2IHB B;  3NYO A;  3V5W A;  2BV1 A;  2V4Z B;  1DK8 A;  3PVW A;  5HE2 A;  3C7L A;  4MK0 A;  2CRP A;  2DLV A;  2AF0 A;  1CMZ A;  3QYF A;  2BCJ A;  1EZY A;  5HE1 A;  4EKD B;  3NYN A;  2D9J A;  3CIK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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