3CC4W

Co-crystal structure of anisomycin bound to the 50s ribosomal subunit
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
154
structure length
154
Chain Sequence
MHALVQLRGEVNMHTDIQDTLEMLNIHHVNHCTLVPETDAYRGMVAKVNDFVAFGEPSQETLETVLATRAEPLEGDADVDDEWVAEHTDYDDISGLAFALLSEETTLREQGLSPTLRLHPPRGGHDGVKHPVKEGGQLGKHDTEGIDDLLEAMR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 46
structure length 154
sequence length 154
ec nomenclature
pdb deposition date 2008-02-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
W PF00327 Ribosomal_L30 Ribosomal protein L30p/L7e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.15.30 Mainly Alpha Orthogonal Bundle 3-methyladenine DNA Glycosylase II; Chain A, domain 3 3-methyladenine DNA Glycosylase II; Chain A, domain 3 3cc4W02
3.30.1390.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein L30; Chain: A, Ribosomal protein L30, ferredoxin-like fold domain 3cc4W01
1VQLW 2OTJW 4WCEW 1VQ4W 1VQ8W 4IO9W 2ZJQW 3CCRW 5GAEa 1Q82X 3CCEW 1YJNW 3CC7W 1VQOW 1YI2W 2QEXW 3CMEW 1Q86X 4IOCW 3CD6W 1W2BV 1VQNW 1JJ2V 1KD1X 1K73X 1K9MX 4WFBW 1YHQW 3CCQW 4IOAW 1BXYA 1VQ5W 4U67W 4WFAW 1YJ9W 5GAHa 2ZJRW 5GADa 3CC4W 3CF5W 1KC8X 1VQ9W 3CCVW 1KQSV 3PIOW 3I56W 1VQ7W 1VQKW 3DLLW 1VQPW 1S72W 1YITW 3CCMW 3PIPW 5GAGa 5DM7W 1N8RX 1K8AX 1VQMW 5HL7W 1M1KX 5JVHW 5JVGW 1VQ6W 3CCLW 3G4SW 3G6EW 1YIJW 3CCSW 1Q81X 3G71W 1YJWW 1QVFV 3CPWV 5DM6W 3CC2W 3CXCV 4UY8Z 4WF9W 3J7ZZ 3CMAW 2QA4W 1NJIX 2ZJPW 1Q7YX 1M90X 3I55W 1QVGV 4WFNW 2OTLW 3CCJW 3OW2V 3CCUW
chains in the Genus database with same CATH superfamily
4YKAA 1VQLW 2OTJW 3D3IA 4WCEW 4CPKA 1VQ4W 1VQ8W 3ZFZA 4IO9W 3ZG5A 2ZJQW 1MWSA 3CCRW 3G1BA 5GAEa 1Q82X 3CCEW 4C1NA 1YJNW 1MBUC 3CC7W 1VQOW 1YI2W 2QEXW 1MG9A 3CMEW 1RQUA 1LZWA 1RQSA 5GW7A 1VQQA 1Q86X 4IOCW 3CD6W 1MBXC 1W2BV 1VQNW 3W7SA 1JJ2V 1KD1X 1K73X 1K9MX 5CA3A 4WFBW 1MBVB 1YHQW 3CCQW 5M18A 4IOAW 1BXYA 3G19A 1R6QC 3DNJA 1VQ5W 4U67W 4WFAW 1R6OC 1YJ9W 1DD3A 5GAHa 2ZJRW 3O1FA 5GADa 3W7UA 2WA8A 1RQVA 3CC4W 3O1FB 3W7TA 2W9RA 3CF5W 1KC8X 1VQ9W 3GQ1A 4BL2A 2WA9A 3CCVW 1KQSV 3PIOW 3I56W 1VQ7W 1VQKW 4YJXA 3DLLW 4CJNA 1VQPW 1S72W 1YITW 3CCMW 3PIPW 5GAGa 1MWRA 5DM7W 1N8RX 3W7WA 1K8AX 1DD4A 1VQMW 5M1AA 3GQ0A 5HL7W 3GW1A 1M1KX 5JVHW 5JVGW 1MWTA 1VQ6W 3O2BA 3G3PA 3ZG0A 3CCLW 3G4SW 3G6EW 1YIJW 3O2OA 3CCSW 1Q81X 3W7XA 4BL3A 3G71W 1YJWW 1QVFV 3CPWV 4DKIA 5DM6W 1CTFA 1MWUA 3CC2W 3O2HA 3CXCV 4YJMA 4UY8Z 4WF9W 3J7ZZ 3CMAW 2QA4W 1NJIX 2ZJPW 1Q7YX 1M90X 3I55W 1QVGV 4WFNW 2OTLW 3CCJW 3OW2V 3CCUW 5M19A
chains in the Genus database with same CATH topology
1VQLW 2OTJW 4WCEW 1VQ4W 1VQ8W 4IO9W 2ZJQW 3CCRW 5GAEa 1Q82X 3CCEW 4C1NA 1YJNW 3CC7W 1VQOW 1YI2W 2QEXW 3CMEW 1Q86X 4IOCW 3CD6W 1W2BV 1VQNW 1JJ2V 1KD1X 1K73X 1K9MX 4WFBW 1YHQW 3CCQW 4IOAW 1BXYA 1VQ5W 4U67W 4WFAW 1YJ9W 5GAHa 2ZJRW 5GADa 3CC4W 3CF5W 1KC8X 1VQ9W 3CCVW 1KQSV 3PIOW 3I56W 1VQ7W 1VQKW 3DLLW 1VQPW 1S72W 1YITW 3CCMW 3PIPW 5GAGa 5DM7W 1N8RX 1K8AX 1VQMW 5HL7W 1M1KX 5JVHW 5JVGW 1VQ6W 3CCLW 3G4SW 3G6EW 1YIJW 3CCSW 1Q81X 3G71W 1YJWW 1QVFV 3CPWV 5DM6W 3CC2W 3CXCV 4UY8Z 4WF9W 3J7ZZ 3CMAW 2QA4W 1NJIX 2ZJPW 1Q7YX 1M90X 3I55W 1QVGV 4WFNW 2OTLW 3CCJW 3OW2V 3CCUW
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VQL W;  2OTJ W;  4WCE W;  1VQ4 W;  1VQ8 W;  4IO9 W;  2ZJQ W;  3CCR W;  5GAE a;  1Q82 X;  3CCE W;  1YJN W;  3CC7 W;  1VQO W;  1YI2 W;  2QEX W;  3CME W;  1Q86 X;  4IOC W;  3CD6 W;  1W2B V;  1VQN W;  1JJ2 V;  1KD1 X;  1K73 X;  1K9M X;  4WFB W;  1YHQ W;  3CCQ W;  4IOA W;  1BXY A;  1VQ5 W;  4U67 W;  4WFA W;  1YJ9 W;  5GAH a;  2ZJR W;  5GAD a;  3CC4 W;  3CF5 W;  1KC8 X;  1VQ9 W;  3CCV W;  1KQS V;  3PIO W;  3I56 W;  1VQ7 W;  1VQK W;  3DLL W;  1VQP W;  1S72 W;  1YIT W;  3CCM W;  3PIP W;  5GAG a;  5DM7 W;  1N8R X;  1K8A X;  1VQM W;  5HL7 W;  1M1K X;  5JVH W;  5JVG W;  1VQ6 W;  3CCL W;  3G4S W;  3G6E W;  1YIJ W;  3CCS W;  1Q81 X;  3G71 W;  1YJW W;  1QVF V;  3CPW V;  5DM6 W;  3CC2 W;  3CXC V;  4UY8 Z;  4WF9 W;  3J7Z Z;  3CMA W;  2QA4 W;  1NJI X;  2ZJP W;  1Q7Y X;  1M90 X;  3I55 W;  1QVG V;  4WFN W;  2OTL W;  3CCJ W;  3OW2 V;  3CCU W; 
#chains in the Genus database with same CATH topology
 4YKA A;  1VQL W;  2OTJ W;  3D3I A;  4WCE W;  4CPK A;  1VQ4 W;  1VQ8 W;  3ZFZ A;  4IO9 W;  3ZG5 A;  2ZJQ W;  1MWS A;  3CCR W;  3G1B A;  5GAE a;  1Q82 X;  3CCE W;  4C1N A;  1YJN W;  1MBU C;  3CC7 W;  1VQO W;  1YI2 W;  2QEX W;  1MG9 A;  3CME W;  1RQU A;  1LZW A;  1RQS A;  5GW7 A;  1VQQ A;  1Q86 X;  4IOC W;  3CD6 W;  1MBX C;  1W2B V;  1VQN W;  3W7S A;  1JJ2 V;  1KD1 X;  1K73 X;  1K9M X;  5CA3 A;  4WFB W;  1MBV B;  1YHQ W;  3CCQ W;  5M18 A;  4IOA W;  1BXY A;  3G19 A;  1R6Q C;  3DNJ A;  1VQ5 W;  4U67 W;  4WFA W;  1R6O C;  1YJ9 W;  1DD3 A;  5GAH a;  2ZJR W;  3O1F A;  5GAD a;  3W7U A;  2WA8 A;  1RQV A;  3CC4 W;  3O1F B;  3W7T A;  2W9R A;  3CF5 W;  1KC8 X;  1VQ9 W;  3GQ1 A;  4BL2 A;  2WA9 A;  3CCV W;  1KQS V;  3PIO W;  3I56 W;  1VQ7 W;  1VQK W;  4YJX A;  3DLL W;  4CJN A;  1VQP W;  1S72 W;  1YIT W;  3CCM W;  3PIP W;  5GAG a;  1MWR A;  5DM7 W;  1N8R X;  3W7W A;  1K8A X;  1DD4 A;  1VQM W;  5M1A A;  3GQ0 A;  5HL7 W;  3GW1 A;  1M1K X;  5JVH W;  5JVG W;  1MWT A;  1VQ6 W;  3O2B A;  3G3P A;  3ZG0 A;  3CCL W;  3G4S W;  3G6E W;  1YIJ W;  3O2O A;  3CCS W;  1Q81 X;  3W7X A;  4BL3 A;  3G71 W;  1YJW W;  1QVF V;  3CPW V;  4DKI A;  5DM6 W;  1CTF A;  1MWU A;  3CC2 W;  3O2H A;  3CXC V;  4YJM A;  4UY8 Z;  4WF9 W;  3J7Z Z;  3CMA W;  2QA4 W;  1NJI X;  2ZJP W;  1Q7Y X;  1M90 X;  3I55 W;  1QVG V;  4WFN W;  2OTL W;  3CCJ W;  3OW2 V;  3CCU W;  5M19 A; 
#chains in the Genus database with same CATH homology
 1VQL W;  2OTJ W;  4WCE W;  1VQ4 W;  1VQ8 W;  4IO9 W;  2ZJQ W;  3CCR W;  5GAE a;  1Q82 X;  3CCE W;  4C1N A;  1YJN W;  3CC7 W;  1VQO W;  1YI2 W;  2QEX W;  3CME W;  1Q86 X;  4IOC W;  3CD6 W;  1W2B V;  1VQN W;  1JJ2 V;  1KD1 X;  1K73 X;  1K9M X;  4WFB W;  1YHQ W;  3CCQ W;  4IOA W;  1BXY A;  1VQ5 W;  4U67 W;  4WFA W;  1YJ9 W;  5GAH a;  2ZJR W;  5GAD a;  3CC4 W;  3CF5 W;  1KC8 X;  1VQ9 W;  3CCV W;  1KQS V;  3PIO W;  3I56 W;  1VQ7 W;  1VQK W;  3DLL W;  1VQP W;  1S72 W;  1YIT W;  3CCM W;  3PIP W;  5GAG a;  5DM7 W;  1N8R X;  1K8A X;  1VQM W;  5HL7 W;  1M1K X;  5JVH W;  5JVG W;  1VQ6 W;  3CCL W;  3G4S W;  3G6E W;  1YIJ W;  3CCS W;  1Q81 X;  3G71 W;  1YJW W;  1QVF V;  3CPW V;  5DM6 W;  3CC2 W;  3CXC V;  4UY8 Z;  4WF9 W;  3J7Z Z;  3CMA W;  2QA4 W;  1NJI X;  2ZJP W;  1Q7Y X;  1M90 X;  3I55 W;  1QVG V;  4WFN W;  2OTL W;  3CCJ W;  3OW2 V;  3CCU W; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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