3CCJW

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation c2534u
Total Genus 43
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
43
sequence length
154
structure length
154
Chain Sequence
MHALVQLRGEVNMHTDIQDTLEMLNIHHVNHCTLVPETDAYRGMVAKVNDFVAFGEPSQETLETVLATRAEPLEGDADVDDEWVAEHTDYDDISGLAFALLSEETTLREQGLSPTLRLHPPRGGHDGVKHPVKEGGQLGKHDTEGIDDLLEAMR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 43
structure length 154
sequence length 154
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
W PF00327 Ribosomal_L30 Ribosomal protein L30p/L7e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.15.30 Mainly Alpha Orthogonal Bundle 3-methyladenine DNA Glycosylase II; Chain A, domain 3 3-methyladenine DNA Glycosylase II; Chain A, domain 3 3ccjW02
3.30.1390.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein L30; Chain: A, Ribosomal protein L30, ferredoxin-like fold domain 3ccjW01
1YJNW 5DM6W 3CMAW 1N8RX 1VQ6W 1NJIX 4IOAW 3OW2V 5DM7W 1VQNW 1VQPW 1YI2W 4IOCW 1VQLW 3CCVW 1W2BV 1JJ2V 4WF9W 1YJ9W 1VQ7W 1KC8X 1VQMW 1QVGV 1K9MX 5JVGW 4WCEW 1YHQW 3CCLW 4WFBW 3CC2W 2ZJQW 3CD6W 3CPWV 3CCMW 5HL7W 3CC7W 1M90X 1VQ9W 5GADa 1M1KX 3CMEW 3DLLW 3I55W 1YJWW 1BXYA 1VQ5W 5GAHa 2QEXW 3G6EW 3CXCV 3CCUW 2ZJPW 3CCSW 3CCRW 5GAGa 4IO9W 1Q86X 3CC4W 3G4SW 4WFNW 1YIJW 4UY8Z 1Q81X 2OTLW 4WFAW 1S72W 1VQOW 5JVHW 1K8AX 1YITW 5GAEa 2OTJW 2ZJRW 1QVFV 1Q7YX 3PIPW 3PIOW 1Q82X 4U67W 3I56W 1VQ8W 2QA4W 1VQKW 3CF5W 3CCJW 3CCQW 3J7ZZ 3G71W 1K73X 3CCEW 1KD1X 1KQSV 1VQ4W
chains in the Genus database with same CATH superfamily
1YJNW 1MWTA 1CTFA 4CJNA 3CMAW 5DM6W 1N8RX 3W7XA 1VQ6W 1NJIX 1LZWA 4IOAW 1MBUC 3GQ1A 5M19A 3OW2V 3G3PA 4BL2A 5M1AA 5DM7W 2WA8A 1VQNW 1VQPW 1YI2W 3G1BA 3DNJA 4IOCW 1DD3A 1R6QC 1VQLW 3CCVW 1W2BV 1JJ2V 4WF9W 4DKIA 1YJ9W 5M18A 1VQ7W 1KC8X 3W7TA 1VQMW 1QVGV 1MWSA 1K9MX 5JVGW 4WCEW 1YHQW 1MWRA 3CCLW 1VQQA 4WFBW 3CC2W 2ZJQW 3W7SA 3W7WA 3CD6W 3ZFZA 3CPWV 3CCMW 2W9RA 5HL7W 3CC7W 1M90X 3ZG0A 1VQ9W 5GADa 3GW1A 1M1KX 3O2BA 3CMEW 3DLLW 3I55W 1YJWW 1BXYA 1VQ5W 5GAHa 2QEXW 3G6EW 3CXCV 4YKAA 2WA9A 3GQ0A 3CCUW 2ZJPW 3O1FA 3CCSW 3CCRW 1MWUA 5GAGa 4BL3A 5GW7A 4IO9W 3W7UA 1Q86X 3CC4W 3G4SW 4WFNW 1YIJW 4UY8Z 1DD4A 1Q81X 2OTLW 4WFAW 1MBVB 3O2HA 1S72W 3O2OA 1VQOW 5JVHW 3ZG5A 1K8AX 1YITW 5GAEa 1RQVA 2OTJW 4YJXA 2ZJRW 1QVFV 1Q7YX 3PIPW 3PIOW 1Q82X 4U67W 4C1NA 3I56W 1VQ8W 2QA4W 1MBXC 1VQKW 1MG9A 1RQSA 1R6OC 3CF5W 3CCJW 3CCQW 3J7ZZ 3G71W 1K73X 3D3IA 3O1FB 5CA3A 4YJMA 3CCEW 1KD1X 1KQSV 3G19A 1VQ4W 1RQUA 4CPKA
chains in the Genus database with same CATH topology
1YJNW 5DM6W 3CMAW 1N8RX 1VQ6W 1NJIX 4IOAW 3OW2V 5DM7W 1VQNW 1VQPW 1YI2W 4IOCW 1VQLW 3CCVW 1W2BV 1JJ2V 4WF9W 1YJ9W 1VQ7W 1KC8X 1VQMW 1QVGV 1K9MX 5JVGW 4WCEW 1YHQW 3CCLW 4WFBW 3CC2W 2ZJQW 3CD6W 3CPWV 3CCMW 5HL7W 3CC7W 1M90X 1VQ9W 5GADa 1M1KX 3CMEW 3DLLW 3I55W 1YJWW 1BXYA 1VQ5W 5GAHa 2QEXW 3G6EW 3CXCV 3CCUW 2ZJPW 3CCSW 3CCRW 5GAGa 4IO9W 1Q86X 3CC4W 3G4SW 4WFNW 1YIJW 4UY8Z 1Q81X 2OTLW 4WFAW 1S72W 1VQOW 5JVHW 1K8AX 1YITW 5GAEa 2OTJW 2ZJRW 1QVFV 1Q7YX 3PIPW 3PIOW 1Q82X 4U67W 4C1NA 3I56W 1VQ8W 2QA4W 1VQKW 3CF5W 3CCJW 3CCQW 3J7ZZ 3G71W 1K73X 3CCEW 1KD1X 1KQSV 1VQ4W
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1YJN W;  5DM6 W;  3CMA W;  1N8R X;  1VQ6 W;  1NJI X;  4IOA W;  3OW2 V;  5DM7 W;  1VQN W;  1VQP W;  1YI2 W;  4IOC W;  1VQL W;  3CCV W;  1W2B V;  1JJ2 V;  4WF9 W;  1YJ9 W;  1VQ7 W;  1KC8 X;  1VQM W;  1QVG V;  1K9M X;  5JVG W;  4WCE W;  1YHQ W;  3CCL W;  4WFB W;  3CC2 W;  2ZJQ W;  3CD6 W;  3CPW V;  3CCM W;  5HL7 W;  3CC7 W;  1M90 X;  1VQ9 W;  5GAD a;  1M1K X;  3CME W;  3DLL W;  3I55 W;  1YJW W;  1BXY A;  1VQ5 W;  5GAH a;  2QEX W;  3G6E W;  3CXC V;  3CCU W;  2ZJP W;  3CCS W;  3CCR W;  5GAG a;  4IO9 W;  1Q86 X;  3CC4 W;  3G4S W;  4WFN W;  1YIJ W;  4UY8 Z;  1Q81 X;  2OTL W;  4WFA W;  1S72 W;  1VQO W;  5JVH W;  1K8A X;  1YIT W;  5GAE a;  2OTJ W;  2ZJR W;  1QVF V;  1Q7Y X;  3PIP W;  3PIO W;  1Q82 X;  4U67 W;  3I56 W;  1VQ8 W;  2QA4 W;  1VQK W;  3CF5 W;  3CCJ W;  3CCQ W;  3J7Z Z;  3G71 W;  1K73 X;  3CCE W;  1KD1 X;  1KQS V;  1VQ4 W; 
#chains in the Genus database with same CATH topology
 1YJN W;  1MWT A;  1CTF A;  4CJN A;  3CMA W;  5DM6 W;  1N8R X;  3W7X A;  1VQ6 W;  1NJI X;  1LZW A;  4IOA W;  1MBU C;  3GQ1 A;  5M19 A;  3OW2 V;  3G3P A;  4BL2 A;  5M1A A;  5DM7 W;  2WA8 A;  1VQN W;  1VQP W;  1YI2 W;  3G1B A;  3DNJ A;  4IOC W;  1DD3 A;  1R6Q C;  1VQL W;  3CCV W;  1W2B V;  1JJ2 V;  4WF9 W;  4DKI A;  1YJ9 W;  5M18 A;  1VQ7 W;  1KC8 X;  3W7T A;  1VQM W;  1QVG V;  1MWS A;  1K9M X;  5JVG W;  4WCE W;  1YHQ W;  1MWR A;  3CCL W;  1VQQ A;  4WFB W;  3CC2 W;  2ZJQ W;  3W7S A;  3W7W A;  3CD6 W;  3ZFZ A;  3CPW V;  3CCM W;  2W9R A;  5HL7 W;  3CC7 W;  1M90 X;  3ZG0 A;  1VQ9 W;  5GAD a;  3GW1 A;  1M1K X;  3O2B A;  3CME W;  3DLL W;  3I55 W;  1YJW W;  1BXY A;  1VQ5 W;  5GAH a;  2QEX W;  3G6E W;  3CXC V;  4YKA A;  2WA9 A;  3GQ0 A;  3CCU W;  2ZJP W;  3O1F A;  3CCS W;  3CCR W;  1MWU A;  5GAG a;  4BL3 A;  5GW7 A;  4IO9 W;  3W7U A;  1Q86 X;  3CC4 W;  3G4S W;  4WFN W;  1YIJ W;  4UY8 Z;  1DD4 A;  1Q81 X;  2OTL W;  4WFA W;  1MBV B;  3O2H A;  1S72 W;  3O2O A;  1VQO W;  5JVH W;  3ZG5 A;  1K8A X;  1YIT W;  5GAE a;  1RQV A;  2OTJ W;  4YJX A;  2ZJR W;  1QVF V;  1Q7Y X;  3PIP W;  3PIO W;  1Q82 X;  4U67 W;  4C1N A;  3I56 W;  1VQ8 W;  2QA4 W;  1MBX C;  1VQK W;  1MG9 A;  1RQS A;  1R6O C;  3CF5 W;  3CCJ W;  3CCQ W;  3J7Z Z;  3G71 W;  1K73 X;  3D3I A;  3O1F B;  5CA3 A;  4YJM A;  3CCE W;  1KD1 X;  1KQS V;  3G19 A;  1VQ4 W;  1RQU A;  4CPK A; 
#chains in the Genus database with same CATH homology
 1YJN W;  5DM6 W;  3CMA W;  1N8R X;  1VQ6 W;  1NJI X;  4IOA W;  3OW2 V;  5DM7 W;  1VQN W;  1VQP W;  1YI2 W;  4IOC W;  1VQL W;  3CCV W;  1W2B V;  1JJ2 V;  4WF9 W;  1YJ9 W;  1VQ7 W;  1KC8 X;  1VQM W;  1QVG V;  1K9M X;  5JVG W;  4WCE W;  1YHQ W;  3CCL W;  4WFB W;  3CC2 W;  2ZJQ W;  3CD6 W;  3CPW V;  3CCM W;  5HL7 W;  3CC7 W;  1M90 X;  1VQ9 W;  5GAD a;  1M1K X;  3CME W;  3DLL W;  3I55 W;  1YJW W;  1BXY A;  1VQ5 W;  5GAH a;  2QEX W;  3G6E W;  3CXC V;  3CCU W;  2ZJP W;  3CCS W;  3CCR W;  5GAG a;  4IO9 W;  1Q86 X;  3CC4 W;  3G4S W;  4WFN W;  1YIJ W;  4UY8 Z;  1Q81 X;  2OTL W;  4WFA W;  1S72 W;  1VQO W;  5JVH W;  1K8A X;  1YIT W;  5GAE a;  2OTJ W;  2ZJR W;  1QVF V;  1Q7Y X;  3PIP W;  3PIO W;  1Q82 X;  4U67 W;  4C1N A;  3I56 W;  1VQ8 W;  2QA4 W;  1VQK W;  3CF5 W;  3CCJ W;  3CCQ W;  3J7Z Z;  3G71 W;  1K73 X;  3CCE W;  1KD1 X;  1KQS V;  1VQ4 W; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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