3CCLW

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation u2535c. density for anisomycin is visible but not included in model.
Total Genus 49
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
49
sequence length
154
structure length
154
Chain Sequence
MHALVQLRGEVNMHTDIQDTLEMLNIHHVNHCTLVPETDAYRGMVAKVNDFVAFGEPSQETLETVLATRAEPLEGDADVDDEWVAEHTDYDDISGLAFALLSEETTLREQGLSPTLRLHPPRGGHDGVKHPVKEGGQLGKHDTEGIDDLLEAMR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 49
structure length 154
sequence length 154
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
W PF00327 Ribosomal_L30 Ribosomal protein L30p/L7e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.15.30 Mainly Alpha Orthogonal Bundle 3-methyladenine DNA Glycosylase II; Chain A, domain 3 3-methyladenine DNA Glycosylase II; Chain A, domain 3 3cclW02
3.30.1390.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein L30; Chain: A, Ribosomal protein L30, ferredoxin-like fold domain 3cclW01
1M90X 1BXYA 1YJWW 3DLLW 4WFBW 5DM7W 3CCRW 5DM6W 3G71W 1NJIX 1VQKW 4WCEW 1Q7YX 1VQ7W 1VQ9W 1M1KX 1VQ8W 4U67W 1YI2W 1Q82X 1VQMW 1QVGV 3CCSW 2ZJQW 2QEXW 3PIOW 1VQ4W 1YJ9W 1Q86X 4IOAW 2QA4W 3CMEW 3CMAW 1VQPW 1VQNW 4WFNW 5JVHW 1K9MX 4IOCW 4WF9W 3CCLW 3CCJW 3J7ZZ 1Q81X 2OTLW 5JVGW 3CD6W 3CCMW 1KC8X 1KQSV 1VQOW 4UY8Z 1YIJW 1K8AX 3G6EW 1YHQW 1W2BV 3CC7W 1N8RX 1VQLW 4IO9W 3I56W 3G4SW 2ZJRW 3CXCV 3CCVW 4WFAW 1S72W 1VQ5W 3CF5W 3CCUW 3I55W 2OTJW 1K73X 5GAGa 5GAHa 3CC4W 1YJNW 3CCQW 3CCEW 3OW2V 5GADa 5HL7W 3PIPW 1JJ2V 1KD1X 1QVFV 2ZJPW 1VQ6W 3CPWV 1YITW 3CC2W 5GAEa
chains in the Genus database with same CATH superfamily
3G3PA 1M90X 1BXYA 3GQ1A 3O2BA 1YJWW 3DLLW 1MWRA 3W7SA 4WFBW 5DM7W 1MG9A 3CCRW 1MWSA 3O1FB 1MBVB 5DM6W 3G71W 1NJIX 1VQKW 5M18A 4WCEW 3W7TA 1Q7YX 1R6OC 1VQ7W 1VQ9W 2WA9A 3GW1A 1M1KX 4CPKA 1VQ8W 4U67W 1YI2W 1Q82X 1VQMW 1QVGV 3CCSW 2ZJQW 4DKIA 2QEXW 3PIOW 1LZWA 1R6QC 1VQ4W 1YJ9W 1Q86X 4CJNA 2QA4W 1CTFA 4IOAW 3CMEW 3CMAW 1VQPW 1VQNW 4WFNW 5M19A 5JVHW 1K9MX 1RQVA 3ZFZA 3W7UA 3DNJA 4YJMA 3O1FA 4IOCW 4WF9W 3CCLW 3CCJW 3J7ZZ 1Q81X 2OTLW 5JVGW 3CD6W 3CCMW 1KC8X 1KQSV 4BL2A 1VQOW 5M1AA 4BL3A 3G19A 4UY8Z 1YIJW 1K8AX 1DD4A 3G6EW 1YHQW 1W2BV 2W9RA 3GQ0A 4YJXA 3CC7W 3W7WA 1N8RX 1VQLW 4IO9W 4YKAA 3I56W 1VQQA 3G4SW 1MWTA 2WA8A 1MWUA 2ZJRW 3CXCV 3G1BA 1RQSA 3CCVW 4WFAW 1S72W 3ZG5A 1VQ5W 3CF5W 3ZG0A 3CCUW 3I55W 1MBXC 2OTJW 1K73X 5GAGa 5GAHa 3CC4W 1YJNW 1DD3A 5CA3A 3CCQW 1MBUC 3CCEW 3OW2V 5GADa 3D3IA 4C1NA 5HL7W 3PIPW 1JJ2V 1KD1X 3O2HA 5GW7A 3O2OA 1QVFV 2ZJPW 1VQ6W 1RQUA 3W7XA 3CPWV 1YITW 3CC2W 5GAEa
chains in the Genus database with same CATH topology
1M90X 1BXYA 1YJWW 3DLLW 4WFBW 5DM7W 3CCRW 5DM6W 3G71W 1NJIX 1VQKW 4WCEW 1Q7YX 1VQ7W 1VQ9W 1M1KX 1VQ8W 4U67W 1YI2W 1Q82X 1VQMW 1QVGV 3CCSW 2ZJQW 2QEXW 3PIOW 1VQ4W 1YJ9W 1Q86X 4IOAW 2QA4W 3CMEW 3CMAW 1VQPW 1VQNW 4WFNW 5JVHW 1K9MX 4IOCW 4WF9W 3CCLW 3CCJW 3J7ZZ 1Q81X 2OTLW 5JVGW 3CD6W 3CCMW 1KC8X 1KQSV 1VQOW 4UY8Z 1YIJW 1K8AX 3G6EW 1YHQW 1W2BV 3CC7W 1N8RX 1VQLW 4IO9W 3I56W 3G4SW 2ZJRW 3CXCV 3CCVW 4WFAW 1S72W 1VQ5W 3CF5W 3CCUW 3I55W 2OTJW 1K73X 5GAGa 5GAHa 3CC4W 1YJNW 3CCQW 3CCEW 3OW2V 5GADa 4C1NA 5HL7W 3PIPW 1JJ2V 1KD1X 1QVFV 2ZJPW 1VQ6W 3CPWV 1YITW 3CC2W 5GAEa
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1M90 X;  1BXY A;  1YJW W;  3DLL W;  4WFB W;  5DM7 W;  3CCR W;  5DM6 W;  3G71 W;  1NJI X;  1VQK W;  4WCE W;  1Q7Y X;  1VQ7 W;  1VQ9 W;  1M1K X;  1VQ8 W;  4U67 W;  1YI2 W;  1Q82 X;  1VQM W;  1QVG V;  3CCS W;  2ZJQ W;  2QEX W;  3PIO W;  1VQ4 W;  1YJ9 W;  1Q86 X;  4IOA W;  2QA4 W;  3CME W;  3CMA W;  1VQP W;  1VQN W;  4WFN W;  5JVH W;  1K9M X;  4IOC W;  4WF9 W;  3CCL W;  3CCJ W;  3J7Z Z;  1Q81 X;  2OTL W;  5JVG W;  3CD6 W;  3CCM W;  1KC8 X;  1KQS V;  1VQO W;  4UY8 Z;  1YIJ W;  1K8A X;  3G6E W;  1YHQ W;  1W2B V;  3CC7 W;  1N8R X;  1VQL W;  4IO9 W;  3I56 W;  3G4S W;  2ZJR W;  3CXC V;  3CCV W;  4WFA W;  1S72 W;  1VQ5 W;  3CF5 W;  3CCU W;  3I55 W;  2OTJ W;  1K73 X;  5GAG a;  5GAH a;  3CC4 W;  1YJN W;  3CCQ W;  3CCE W;  3OW2 V;  5GAD a;  5HL7 W;  3PIP W;  1JJ2 V;  1KD1 X;  1QVF V;  2ZJP W;  1VQ6 W;  3CPW V;  1YIT W;  3CC2 W;  5GAE a; 
#chains in the Genus database with same CATH topology
 3G3P A;  1M90 X;  1BXY A;  3GQ1 A;  3O2B A;  1YJW W;  3DLL W;  1MWR A;  3W7S A;  4WFB W;  5DM7 W;  1MG9 A;  3CCR W;  1MWS A;  3O1F B;  1MBV B;  5DM6 W;  3G71 W;  1NJI X;  1VQK W;  5M18 A;  4WCE W;  3W7T A;  1Q7Y X;  1R6O C;  1VQ7 W;  1VQ9 W;  2WA9 A;  3GW1 A;  1M1K X;  4CPK A;  1VQ8 W;  4U67 W;  1YI2 W;  1Q82 X;  1VQM W;  1QVG V;  3CCS W;  2ZJQ W;  4DKI A;  2QEX W;  3PIO W;  1LZW A;  1R6Q C;  1VQ4 W;  1YJ9 W;  1Q86 X;  4CJN A;  2QA4 W;  1CTF A;  4IOA W;  3CME W;  3CMA W;  1VQP W;  1VQN W;  4WFN W;  5M19 A;  5JVH W;  1K9M X;  1RQV A;  3ZFZ A;  3W7U A;  3DNJ A;  4YJM A;  3O1F A;  4IOC W;  4WF9 W;  3CCL W;  3CCJ W;  3J7Z Z;  1Q81 X;  2OTL W;  5JVG W;  3CD6 W;  3CCM W;  1KC8 X;  1KQS V;  4BL2 A;  1VQO W;  5M1A A;  4BL3 A;  3G19 A;  4UY8 Z;  1YIJ W;  1K8A X;  1DD4 A;  3G6E W;  1YHQ W;  1W2B V;  2W9R A;  3GQ0 A;  4YJX A;  3CC7 W;  3W7W A;  1N8R X;  1VQL W;  4IO9 W;  4YKA A;  3I56 W;  1VQQ A;  3G4S W;  1MWT A;  2WA8 A;  1MWU A;  2ZJR W;  3CXC V;  3G1B A;  1RQS A;  3CCV W;  4WFA W;  1S72 W;  3ZG5 A;  1VQ5 W;  3CF5 W;  3ZG0 A;  3CCU W;  3I55 W;  1MBX C;  2OTJ W;  1K73 X;  5GAG a;  5GAH a;  3CC4 W;  1YJN W;  1DD3 A;  5CA3 A;  3CCQ W;  1MBU C;  3CCE W;  3OW2 V;  5GAD a;  3D3I A;  4C1N A;  5HL7 W;  3PIP W;  1JJ2 V;  1KD1 X;  3O2H A;  5GW7 A;  3O2O A;  1QVF V;  2ZJP W;  1VQ6 W;  1RQU A;  3W7X A;  3CPW V;  1YIT W;  3CC2 W;  5GAE a; 
#chains in the Genus database with same CATH homology
 1M90 X;  1BXY A;  1YJW W;  3DLL W;  4WFB W;  5DM7 W;  3CCR W;  5DM6 W;  3G71 W;  1NJI X;  1VQK W;  4WCE W;  1Q7Y X;  1VQ7 W;  1VQ9 W;  1M1K X;  1VQ8 W;  4U67 W;  1YI2 W;  1Q82 X;  1VQM W;  1QVG V;  3CCS W;  2ZJQ W;  2QEX W;  3PIO W;  1VQ4 W;  1YJ9 W;  1Q86 X;  4IOA W;  2QA4 W;  3CME W;  3CMA W;  1VQP W;  1VQN W;  4WFN W;  5JVH W;  1K9M X;  4IOC W;  4WF9 W;  3CCL W;  3CCJ W;  3J7Z Z;  1Q81 X;  2OTL W;  5JVG W;  3CD6 W;  3CCM W;  1KC8 X;  1KQS V;  1VQO W;  4UY8 Z;  1YIJ W;  1K8A X;  3G6E W;  1YHQ W;  1W2B V;  3CC7 W;  1N8R X;  1VQL W;  4IO9 W;  3I56 W;  3G4S W;  2ZJR W;  3CXC V;  3CCV W;  4WFA W;  1S72 W;  1VQ5 W;  3CF5 W;  3CCU W;  3I55 W;  2OTJ W;  1K73 X;  5GAG a;  5GAH a;  3CC4 W;  1YJN W;  3CCQ W;  3CCE W;  3OW2 V;  5GAD a;  4C1N A;  5HL7 W;  3PIP W;  1JJ2 V;  1KD1 X;  1QVF V;  2ZJP W;  1VQ6 W;  3CPW V;  1YIT W;  3CC2 W;  5GAE a; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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