3CCQW

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation a2488u
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
154
structure length
154
Chain Sequence
MHALVQLRGEVNMHTDIQDTLEMLNIHHVNHCTLVPETDAYRGMVAKVNDFVAFGEPSQETLETVLATRAEPLEGDADVDDEWVAEHTDYDDISGLAFALLSEETTLREQGLSPTLRLHPPRGGHDGVKHPVKEGGQLGKHDTEGIDDLLEAMR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 50
structure length 154
sequence length 154
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
W PF00327 Ribosomal_L30 Ribosomal protein L30p/L7e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.15.30 Mainly Alpha Orthogonal Bundle 3-methyladenine DNA Glycosylase II; Chain A, domain 3 3-methyladenine DNA Glycosylase II; Chain A, domain 3 3ccqW02
3.30.1390.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein L30; Chain: A, Ribosomal protein L30, ferredoxin-like fold domain 3ccqW01
4WFAW 1VQ5W 1VQ7W 1BXYA 2ZJQW 3CCMW 4IO9W 1YI2W 1VQ8W 1VQLW 1VQ9W 3PIPW 1QVGV 4IOAW 1Q81X 3PIOW 1VQ4W 1VQ6W 3G4SW 2OTLW 1VQPW 3CC7W 1Q82X 4WF9W 5GAHa 3I55W 3CF5W 1VQNW 3CPWV 2OTJW 3CCRW 1K9MX 3CD6W 1KQSV 1S72W 1YITW 5JVHW 2QA4W 5GAGa 1YJ9W 4U67W 3CMEW 3CC2W 1JJ2V 3I56W 3CC4W 5GAEa 3CCEW 3CCVW 3OW2V 4UY8Z 3G6EW 5GADa 4WFNW 3CCUW 4WCEW 1Q7YX 1K8AX 2ZJPW 1N8RX 1YJNW 5DM6W 5HL7W 3DLLW 3CMAW 1VQOW 1K73X 2QEXW 1KD1X 3CXCV 3J7ZZ 1M1KX 1YJWW 3CCQW 1W2BV 5JVGW 1KC8X 1M90X 1VQMW 3CCJW 4WFBW 1Q86X 3G71W 4IOCW 3CCLW 3CCSW 1NJIX 1QVFV 1YHQW 1YIJW 2ZJRW 1VQKW 5DM7W
chains in the Genus database with same CATH superfamily
4WFAW 4DKIA 1VQ5W 2WA9A 1MWSA 3ZG0A 3O1FB 1VQ7W 1BXYA 1R6QC 2ZJQW 3CCMW 4IO9W 1YI2W 1VQ8W 3ZFZA 4BL2A 1VQLW 1VQ9W 3PIPW 5GW7A 1QVGV 1RQVA 4IOAW 1Q81X 3PIOW 3GQ1A 1VQ4W 1LZWA 3O2HA 1VQ6W 5M18A 3G4SW 2OTLW 1VQPW 3G3PA 3CC7W 1CTFA 1Q82X 3O2BA 5GAHa 3I55W 4WF9W 3CF5W 1VQNW 3O1FA 3CPWV 2OTJW 3CCRW 1K9MX 3CD6W 1KQSV 1S72W 1YITW 5JVHW 2QA4W 5GAGa 1YJ9W 4U67W 1DD3A 3CMEW 3CC2W 3W7SA 3GW1A 1RQSA 1MWTA 3W7XA 1MWRA 1JJ2V 3ZG5A 4CPKA 3DNJA 3W7UA 1R6OC 3I56W 3W7WA 3CC4W 5GAEa 3GQ0A 3CCEW 1MBUC 3CCVW 3OW2V 4YJMA 4UY8Z 3G6EW 5GADa 4WFNW 3CCUW 1RQUA 1MBVB 4YKAA 4WCEW 4YJXA 1Q7YX 1MBXC 1K8AX 2ZJPW 1N8RX 2WA8A 1YJNW 5DM6W 5HL7W 3DLLW 3CMAW 1VQOW 1K73X 2QEXW 1VQQA 1KD1X 3CXCV 4BL3A 3J7ZZ 1M1KX 1YJWW 3CCQW 1MG9A 1W2BV 5JVGW 1KC8X 1M90X 3G1BA 1VQMW 3CCJW 4C1NA 4WFBW 5CA3A 1Q86X 1DD4A 3G71W 4IOCW 5M19A 3CCLW 3CCSW 1NJIX 1QVFV 1YHQW 5M1AA 3G19A 1YIJW 2ZJRW 1VQKW 5DM7W 3D3IA 3W7TA 3O2OA 4CJNA 2W9RA 1MWUA
chains in the Genus database with same CATH topology
4WFAW 1VQ5W 1VQ7W 1BXYA 2ZJQW 3CCMW 4IO9W 1YI2W 1VQ8W 1VQLW 1VQ9W 3PIPW 1QVGV 4IOAW 1Q81X 3PIOW 1VQ4W 1VQ6W 3G4SW 2OTLW 1VQPW 3CC7W 1Q82X 4WF9W 5GAHa 3I55W 3CF5W 1VQNW 3CPWV 2OTJW 3CCRW 1K9MX 3CD6W 1KQSV 1S72W 1YITW 5JVHW 2QA4W 5GAGa 1YJ9W 4U67W 3CMEW 3CC2W 1JJ2V 3I56W 3CC4W 5GAEa 3CCEW 3CCVW 3OW2V 4UY8Z 3G6EW 5GADa 4WFNW 3CCUW 4WCEW 1Q7YX 1K8AX 2ZJPW 1N8RX 1YJNW 5DM6W 5HL7W 3DLLW 3CMAW 1VQOW 1K73X 2QEXW 1KD1X 3CXCV 3J7ZZ 1M1KX 1YJWW 3CCQW 1W2BV 5JVGW 1KC8X 1M90X 1VQMW 3CCJW 4C1NA 4WFBW 1Q86X 3G71W 4IOCW 3CCLW 3CCSW 1NJIX 1QVFV 1YHQW 1YIJW 2ZJRW 1VQKW 5DM7W
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4WFA W;  1VQ5 W;  1VQ7 W;  1BXY A;  2ZJQ W;  3CCM W;  4IO9 W;  1YI2 W;  1VQ8 W;  1VQL W;  1VQ9 W;  3PIP W;  1QVG V;  4IOA W;  1Q81 X;  3PIO W;  1VQ4 W;  1VQ6 W;  3G4S W;  2OTL W;  1VQP W;  3CC7 W;  1Q82 X;  4WF9 W;  5GAH a;  3I55 W;  3CF5 W;  1VQN W;  3CPW V;  2OTJ W;  3CCR W;  1K9M X;  3CD6 W;  1KQS V;  1S72 W;  1YIT W;  5JVH W;  2QA4 W;  5GAG a;  1YJ9 W;  4U67 W;  3CME W;  3CC2 W;  1JJ2 V;  3I56 W;  3CC4 W;  5GAE a;  3CCE W;  3CCV W;  3OW2 V;  4UY8 Z;  3G6E W;  5GAD a;  4WFN W;  3CCU W;  4WCE W;  1Q7Y X;  1K8A X;  2ZJP W;  1N8R X;  1YJN W;  5DM6 W;  5HL7 W;  3DLL W;  3CMA W;  1VQO W;  1K73 X;  2QEX W;  1KD1 X;  3CXC V;  3J7Z Z;  1M1K X;  1YJW W;  3CCQ W;  1W2B V;  5JVG W;  1KC8 X;  1M90 X;  1VQM W;  3CCJ W;  4WFB W;  1Q86 X;  3G71 W;  4IOC W;  3CCL W;  3CCS W;  1NJI X;  1QVF V;  1YHQ W;  1YIJ W;  2ZJR W;  1VQK W;  5DM7 W; 
#chains in the Genus database with same CATH topology
 4WFA W;  4DKI A;  1VQ5 W;  2WA9 A;  1MWS A;  3ZG0 A;  3O1F B;  1VQ7 W;  1BXY A;  1R6Q C;  2ZJQ W;  3CCM W;  4IO9 W;  1YI2 W;  1VQ8 W;  3ZFZ A;  4BL2 A;  1VQL W;  1VQ9 W;  3PIP W;  5GW7 A;  1QVG V;  1RQV A;  4IOA W;  1Q81 X;  3PIO W;  3GQ1 A;  1VQ4 W;  1LZW A;  3O2H A;  1VQ6 W;  5M18 A;  3G4S W;  2OTL W;  1VQP W;  3G3P A;  3CC7 W;  1CTF A;  1Q82 X;  3O2B A;  5GAH a;  3I55 W;  4WF9 W;  3CF5 W;  1VQN W;  3O1F A;  3CPW V;  2OTJ W;  3CCR W;  1K9M X;  3CD6 W;  1KQS V;  1S72 W;  1YIT W;  5JVH W;  2QA4 W;  5GAG a;  1YJ9 W;  4U67 W;  1DD3 A;  3CME W;  3CC2 W;  3W7S A;  3GW1 A;  1RQS A;  1MWT A;  3W7X A;  1MWR A;  1JJ2 V;  3ZG5 A;  4CPK A;  3DNJ A;  3W7U A;  1R6O C;  3I56 W;  3W7W A;  3CC4 W;  5GAE a;  3GQ0 A;  3CCE W;  1MBU C;  3CCV W;  3OW2 V;  4YJM A;  4UY8 Z;  3G6E W;  5GAD a;  4WFN W;  3CCU W;  1RQU A;  1MBV B;  4YKA A;  4WCE W;  4YJX A;  1Q7Y X;  1MBX C;  1K8A X;  2ZJP W;  1N8R X;  2WA8 A;  1YJN W;  5DM6 W;  5HL7 W;  3DLL W;  3CMA W;  1VQO W;  1K73 X;  2QEX W;  1VQQ A;  1KD1 X;  3CXC V;  4BL3 A;  3J7Z Z;  1M1K X;  1YJW W;  3CCQ W;  1MG9 A;  1W2B V;  5JVG W;  1KC8 X;  1M90 X;  3G1B A;  1VQM W;  3CCJ W;  4C1N A;  4WFB W;  5CA3 A;  1Q86 X;  1DD4 A;  3G71 W;  4IOC W;  5M19 A;  3CCL W;  3CCS W;  1NJI X;  1QVF V;  1YHQ W;  5M1A A;  3G19 A;  1YIJ W;  2ZJR W;  1VQK W;  5DM7 W;  3D3I A;  3W7T A;  3O2O A;  4CJN A;  2W9R A;  1MWU A; 
#chains in the Genus database with same CATH homology
 4WFA W;  1VQ5 W;  1VQ7 W;  1BXY A;  2ZJQ W;  3CCM W;  4IO9 W;  1YI2 W;  1VQ8 W;  1VQL W;  1VQ9 W;  3PIP W;  1QVG V;  4IOA W;  1Q81 X;  3PIO W;  1VQ4 W;  1VQ6 W;  3G4S W;  2OTL W;  1VQP W;  3CC7 W;  1Q82 X;  4WF9 W;  5GAH a;  3I55 W;  3CF5 W;  1VQN W;  3CPW V;  2OTJ W;  3CCR W;  1K9M X;  3CD6 W;  1KQS V;  1S72 W;  1YIT W;  5JVH W;  2QA4 W;  5GAG a;  1YJ9 W;  4U67 W;  3CME W;  3CC2 W;  1JJ2 V;  3I56 W;  3CC4 W;  5GAE a;  3CCE W;  3CCV W;  3OW2 V;  4UY8 Z;  3G6E W;  5GAD a;  4WFN W;  3CCU W;  4WCE W;  1Q7Y X;  1K8A X;  2ZJP W;  1N8R X;  1YJN W;  5DM6 W;  5HL7 W;  3DLL W;  3CMA W;  1VQO W;  1K73 X;  2QEX W;  1KD1 X;  3CXC V;  3J7Z Z;  1M1K X;  1YJW W;  3CCQ W;  1W2B V;  5JVG W;  1KC8 X;  1M90 X;  1VQM W;  3CCJ W;  4C1N A;  4WFB W;  1Q86 X;  3G71 W;  4IOC W;  3CCL W;  3CCS W;  1NJI X;  1QVF V;  1YHQ W;  1YIJ W;  2ZJR W;  1VQK W;  5DM7 W; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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