3CCVH

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation g2616a
Total Genus 42
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
42
sequence length
171
structure length
160
Chain Sequence
KPASMYRDIDKPAYTRREYITGIPGSKIAQHKMGRKQKDADDYPVQISLIVEETVQLRHGSLEASRLSANRHLIKELGEEGDYKMTLRKFPHQVLRENKDGMRAAFGKIVGTAARVQAGEQLFTAYCNVEDAEHVKEAFRRAYNKITPSCRIKVERGEEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 42
structure length 160
sequence length 171
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
H PF00252 Ribosomal_L16 Ribosomal protein L16p/L10e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1170.10 Alpha Beta Alpha-Beta Complex Aldehyde Oxidoreductase; domain 3 Ribosomal protein L10e/L16 3ccvH00
1Q82J 2ZJRJ 3CMAH 1NJIJ 1VQMH 1QVGH 2PA2A 1VQOH 1K8AJ 3CXCH 4WFAJ 2ZJQJ 3CCRH 5GAEN 3CCVH 5MLCO 4U67J 4UY8M 3G4SH 2QEXH 1YIJH 4WF9J 2ZJPJ 4IOAJ 3CCJH 2OTLH 2QA4H 5H1SO 3CC2H 3CCSH 1M90J 5DM7J 1YI2H 1VQ6H 1Q81J 1VQ5H 1VQLH 3CD6H 1N8RJ 3PIOJ 1JJ2H 1KQSH 3PIPJ 1YJNH 1VQ8H 1M1KJ 4WFNJ 5AN9F 2OTJH 3OW2H 1VQNH 1VQ9H 5DM6J 4IO9J 1K73J 1K9MJ 1YJWH 1VQKH 3CCLH 4WCEJ 1WKIA 3CMEH 1Q7YJ 1VQ4H 3CC7H 5JVHJ 4IOCJ 1YITH 3CCEH 1W2BH 1VQPH 1S72H 1Q86J 3J7ZM 1QVFH 3CCUH 5GADN 3DLLJ 1KD1J 3G71H 1Y69K 1YHQH 3CPWH 5GAGN 5JVGJ 3CF5J 5HL7J 1VQ7H 3G6EH 3I55H 3CC4H 3CCQH 1KC8J 5GAHN 4WFBJ 1YJ9H 3I56H 3CCMH
chains in the Genus database with same CATH superfamily
3NVZC 1Q82J 2ZJRJ 4KWVA 5AYXA 3SR6C 3C2FA 1O4UA 3CMAH 1NVIE 3L4PA 2W3RB 1UOUA 1NJIJ 1VQMH 5HULA 1FIQC 1QVGH 1VLBA 4GA4A 2PA2A 3WO0A 2WK6A 1VQOH 1FO4A 1K8AJ 3C2VA 3NVWC 3CXCH 1RM6A 4X46A 4USAA 4WFAJ 1YTEA 4EADA 2Q5WE 2W54B 5EP8A 2ZJQJ 3CCRH 5GAEN 3CCVH 5EY3A 3AMZA 5MLCO 4U67J 4UY8M 3G4SH 2QEXH 1YIJH 1FM0E 4I9AA 2OMDA 1JRPB 4WF9J 2ZJPJ 5HUOA 4IOAJ 3NS1C 1OTPA 2E3TA 3CCJH 2I14A 1AZYA 4XR5A 5AYYA 2QA4H 2OTLH 3FC4A 5H1SO 3CC2H 1VDVA 3WNZA 3CCSH 4YYYA 1M90J 5DM7J 1YI2H 1VQ6H 3C2OA 1Q81J 1VQ5H 1VQLH 3CD6H 1N8RJ 3GNNA 5HUPA 3PIOJ 1JJ2H 5AYZA 1N5WB 1KQSH 2I1OA 2W55B 3BIIE 3PIPJ 1YJNH 3NVVC 1FFUB 1VQ8H 1WYGA 1M1KJ 3AM9A 3L0GA 4WFNJ 1NVJA 5AN9F 3C2EA 3VMMA 2OTJH 3NVYC 3OW2H 3B9JC 2B7PA 4GA6A 1VQNH 1VQ9H 1QPOA 4US8A 5DM6J 4IO9J 2TPTA 1K73J 3ETRC 1K9MJ 1YJWH 3H5QA 1BRWA 1V97A 1VQKH 3CCLH 4WCEJ 1WKIA 3CMEH 2B7NA 3AN1A 1Q7YJ 1VQ4H 3CC7H 2DSJA 1N62B 1QAPA 5JVHJ 4IOCJ 1SIJA 1YITH 3CCEH 1W2BH 1VQPH 1S72H 4US9A 1YTDA 1Q86J 5MPOC 3FAHA 3J7ZM 1QVFH 3TQVA 3CCUH 4LHMA 3EUB4 1N5XA 2B7QA 3RPFA 5GADN 1KD1J 3DLLJ 4C7YA 3G71H 2JBMA 1QPQA 1Y69K 1DGJA 3C2RA 4AP8A 1FFVB 1YHQH 4ZOHA 1FMAE 1QPRA 1JROB 2W3SB 3CPWH 1N63B 1QPNA 1ZXIB 4GA5A 5GAGN 5JVGJ 3CF5J 1X1OA 5HL7J 4C7ZA 1YTKA 1N60B 3G6EH 1VQ7H 3NRZC 2WP4A 1N61B 3I55H 3CC4H 3PAJA 4EAFA 4C80A 3CCQH 1KC8J 2J0FA 2QIEA 5GAHN 4YEKA 4WFBJ 1SB3A 1YJ9H 3I56H 3CCMH 2WK5A 3WO1A 4KWWA
chains in the Genus database with same CATH topology
1Q82J 2ZJRJ 3CMAH 1NJIJ 1VQMH 1QVGH 2PA2A 1VQOH 1K8AJ 3CXCH 4WFAJ 2ZJQJ 3CCRH 5GAEN 3CCVH 5MLCO 4U67J 4UY8M 3G4SH 2QEXH 1YIJH 4WF9J 2ZJPJ 4IOAJ 3CCJH 2OTLH 2QA4H 5H1SO 3CC2H 3CCSH 1M90J 5DM7J 1YI2H 1VQ6H 1Q81J 1VQ5H 1VQLH 3CD6H 1N8RJ 3PIOJ 1JJ2H 1KQSH 3PIPJ 1YJNH 1VQ8H 1M1KJ 4WFNJ 5AN9F 2OTJH 3OW2H 1VQNH 1VQ9H 5DM6J 4IO9J 1K73J 1K9MJ 1YJWH 1VQKH 3CCLH 4WCEJ 1WKIA 3CMEH 1Q7YJ 1VQ4H 3CC7H 5JVHJ 4IOCJ 1YITH 3CCEH 1W2BH 1VQPH 1S72H 1Q86J 3J7ZM 1QVFH 3CCUH 5GADN 3DLLJ 1KD1J 3G71H 1Y69K 1YHQH 3CPWH 5GAGN 5JVGJ 3CF5J 5HL7J 1VQ7H 3G6EH 3I55H 3CC4H 3CCQH 1KC8J 5GAHN 4WFBJ 1YJ9H 3I56H 3CCMH
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1Q82 J;  2ZJR J;  3CMA H;  1NJI J;  1VQM H;  1QVG H;  2PA2 A;  1VQO H;  1K8A J;  3CXC H;  4WFA J;  2ZJQ J;  3CCR H;  5GAE N;  3CCV H;  5MLC O;  4U67 J;  4UY8 M;  3G4S H;  2QEX H;  1YIJ H;  4WF9 J;  2ZJP J;  4IOA J;  3CCJ H;  2OTL H;  2QA4 H;  5H1S O;  3CC2 H;  3CCS H;  1M90 J;  5DM7 J;  1YI2 H;  1VQ6 H;  1Q81 J;  1VQ5 H;  1VQL H;  3CD6 H;  1N8R J;  3PIO J;  1JJ2 H;  1KQS H;  3PIP J;  1YJN H;  1VQ8 H;  1M1K J;  4WFN J;  5AN9 F;  2OTJ H;  3OW2 H;  1VQN H;  1VQ9 H;  5DM6 J;  4IO9 J;  1K73 J;  1K9M J;  1YJW H;  1VQK H;  3CCL H;  4WCE J;  1WKI A;  3CME H;  1Q7Y J;  1VQ4 H;  3CC7 H;  5JVH J;  4IOC J;  1YIT H;  3CCE H;  1W2B H;  1VQP H;  1S72 H;  1Q86 J;  3J7Z M;  1QVF H;  3CCU H;  5GAD N;  3DLL J;  1KD1 J;  3G71 H;  1Y69 K;  1YHQ H;  3CPW H;  5GAG N;  5JVG J;  3CF5 J;  5HL7 J;  1VQ7 H;  3G6E H;  3I55 H;  3CC4 H;  3CCQ H;  1KC8 J;  5GAH N;  4WFB J;  1YJ9 H;  3I56 H;  3CCM H; 
#chains in the Genus database with same CATH topology
 3NVZ C;  1Q82 J;  2ZJR J;  4KWV A;  5AYX A;  3SR6 C;  3C2F A;  1O4U A;  3CMA H;  1NVI E;  3L4P A;  2W3R B;  1UOU A;  1NJI J;  1VQM H;  5HUL A;  1FIQ C;  1QVG H;  1VLB A;  4GA4 A;  2PA2 A;  3WO0 A;  2WK6 A;  1VQO H;  1FO4 A;  1K8A J;  3C2V A;  3NVW C;  3CXC H;  1RM6 A;  4X46 A;  4USA A;  4WFA J;  1YTE A;  4EAD A;  2Q5W E;  2W54 B;  5EP8 A;  2ZJQ J;  3CCR H;  5GAE N;  3CCV H;  5EY3 A;  3AMZ A;  5MLC O;  4U67 J;  4UY8 M;  3G4S H;  2QEX H;  1YIJ H;  1FM0 E;  4I9A A;  2OMD A;  1JRP B;  4WF9 J;  2ZJP J;  5HUO A;  4IOA J;  3NS1 C;  1OTP A;  2E3T A;  3CCJ H;  2I14 A;  1AZY A;  4XR5 A;  5AYY A;  2QA4 H;  2OTL H;  3FC4 A;  5H1S O;  3CC2 H;  1VDV A;  3WNZ A;  3CCS H;  4YYY A;  1M90 J;  5DM7 J;  1YI2 H;  1VQ6 H;  3C2O A;  1Q81 J;  1VQ5 H;  1VQL H;  3CD6 H;  1N8R J;  3GNN A;  5HUP A;  3PIO J;  1JJ2 H;  5AYZ A;  1N5W B;  1KQS H;  2I1O A;  2W55 B;  3BII E;  3PIP J;  1YJN H;  3NVV C;  1FFU B;  1VQ8 H;  1WYG A;  1M1K J;  3AM9 A;  3L0G A;  4WFN J;  1NVJ A;  5AN9 F;  3C2E A;  3VMM A;  2OTJ H;  3NVY C;  3OW2 H;  3B9J C;  2B7P A;  4GA6 A;  1VQN H;  1VQ9 H;  1QPO A;  4US8 A;  5DM6 J;  4IO9 J;  2TPT A;  1K73 J;  3ETR C;  1K9M J;  1YJW H;  3H5Q A;  1BRW A;  1V97 A;  1VQK H;  3CCL H;  4WCE J;  1WKI A;  3CME H;  2B7N A;  3AN1 A;  1Q7Y J;  1VQ4 H;  3CC7 H;  2DSJ A;  1N62 B;  1QAP A;  5JVH J;  4IOC J;  1SIJ A;  1YIT H;  3CCE H;  1W2B H;  1VQP H;  1S72 H;  4US9 A;  1YTD A;  1Q86 J;  5MPO C;  3FAH A;  3J7Z M;  1QVF H;  3TQV A;  3CCU H;  4LHM A;  3EUB 4;  1N5X A;  2B7Q A;  3RPF A;  5GAD N;  1KD1 J;  3DLL J;  4C7Y A;  3G71 H;  2JBM A;  1QPQ A;  1Y69 K;  1DGJ A;  3C2R A;  4AP8 A;  1FFV B;  1YHQ H;  4ZOH A;  1FMA E;  1QPR A;  1JRO B;  2W3S B;  3CPW H;  1N63 B;  1QPN A;  1ZXI B;  4GA5 A;  5GAG N;  5JVG J;  3CF5 J;  1X1O A;  5HL7 J;  4C7Z A;  1YTK A;  1N60 B;  3G6E H;  1VQ7 H;  3NRZ C;  2WP4 A;  1N61 B;  3I55 H;  3CC4 H;  3PAJ A;  4EAF A;  4C80 A;  3CCQ H;  1KC8 J;  2J0F A;  2QIE A;  5GAH N;  4YEK A;  4WFB J;  1SB3 A;  1YJ9 H;  3I56 H;  3CCM H;  2WK5 A;  3WO1 A;  4KWW A; 
#chains in the Genus database with same CATH homology
 1Q82 J;  2ZJR J;  3CMA H;  1NJI J;  1VQM H;  1QVG H;  2PA2 A;  1VQO H;  1K8A J;  3CXC H;  4WFA J;  2ZJQ J;  3CCR H;  5GAE N;  3CCV H;  5MLC O;  4U67 J;  4UY8 M;  3G4S H;  2QEX H;  1YIJ H;  4WF9 J;  2ZJP J;  4IOA J;  3CCJ H;  2OTL H;  2QA4 H;  5H1S O;  3CC2 H;  3CCS H;  1M90 J;  5DM7 J;  1YI2 H;  1VQ6 H;  1Q81 J;  1VQ5 H;  1VQL H;  3CD6 H;  1N8R J;  3PIO J;  1JJ2 H;  1KQS H;  3PIP J;  1YJN H;  1VQ8 H;  1M1K J;  4WFN J;  5AN9 F;  2OTJ H;  3OW2 H;  1VQN H;  1VQ9 H;  5DM6 J;  4IO9 J;  1K73 J;  1K9M J;  1YJW H;  1VQK H;  3CCL H;  4WCE J;  1WKI A;  3CME H;  1Q7Y J;  1VQ4 H;  3CC7 H;  5JVH J;  4IOC J;  1YIT H;  3CCE H;  1W2B H;  1VQP H;  1S72 H;  1Q86 J;  3J7Z M;  1QVF H;  3CCU H;  5GAD N;  3DLL J;  1KD1 J;  3G71 H;  1Y69 K;  1YHQ H;  3CPW H;  5GAG N;  5JVG J;  3CF5 J;  5HL7 J;  1VQ7 H;  3G6E H;  3I55 H;  3CC4 H;  3CCQ H;  1KC8 J;  5GAH N;  4WFB J;  1YJ9 H;  3I56 H;  3CCM H; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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