3CCVW

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation g2616a
Total Genus 49
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
49
sequence length
154
structure length
154
Chain Sequence
MHALVQLRGEVNMHTDIQDTLEMLNIHHVNHCTLVPETDAYRGMVAKVNDFVAFGEPSQETLETVLATRAEPLEGDADVDDEWVAEHTDYDDISGLAFALLSEETTLREQGLSPTLRLHPPRGGHDGVKHPVKEGGQLGKHDTEGIDDLLEAMR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 49
structure length 154
sequence length 154
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
W PF00327 Ribosomal_L30 Ribosomal protein L30p/L7e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.15.30 Mainly Alpha Orthogonal Bundle 3-methyladenine DNA Glycosylase II; Chain A, domain 3 3-methyladenine DNA Glycosylase II; Chain A, domain 3 3ccvW02
3.30.1390.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein L30; Chain: A, Ribosomal protein L30, ferredoxin-like fold domain 3ccvW01
5DM6W 5GAEa 4U67W 4IOAW 2QEXW 3PIOW 1VQ9W 1QVFV 3I56W 5HL7W 4UY8Z 1Q7YX 4WF9W 1VQ5W 1VQ7W 1YIJW 4IOCW 4WCEW 3CF5W 1YI2W 2OTJW 4WFNW 1M1KX 3CCSW 3G4SW 1VQOW 3CMEW 2QA4W 3I55W 2ZJRW 5JVHW 3CCUW 1NJIX 4WFAW 3CC4W 3OW2V 1VQKW 5GAHa 1JJ2V 1VQ4W 1YITW 3CCMW 1VQNW 5DM7W 3CC2W 1YJWW 1VQLW 1N8RX 3CCQW 1YJ9W 3CMAW 1QVGV 1YJNW 3PIPW 3CXCV 1VQ8W 3CCLW 5GAGa 1Q81X 3J7ZZ 2ZJQW 1M90X 1BXYA 3CCVW 3CCRW 1VQMW 3CD6W 1KQSV 3CCEW 3CCJW 3G6EW 3DLLW 1VQ6W 4IO9W 1W2BV 5JVGW 1KD1X 1K9MX 1S72W 5GADa 3G71W 3CC7W 4WFBW 1K8AX 1YHQW 1Q86X 1Q82X 1K73X 1VQPW 1KC8X 2ZJPW 2OTLW 3CPWV
chains in the Genus database with same CATH superfamily
3G19A 5DM6W 5GAEa 4U67W 4IOAW 2QEXW 3PIOW 1VQ9W 1QVFV 3I56W 5M1AA 5HL7W 4UY8Z 1MWTA 1Q7YX 1MBXC 4WF9W 1VQ5W 1R6OC 1VQ7W 1YIJW 4IOCW 4YKAA 1LZWA 4WCEW 3CF5W 1YI2W 2OTJW 3ZG5A 4WFNW 1M1KX 3CCSW 3D3IA 3G4SW 1VQOW 3GQ0A 3CMEW 2QA4W 3I55W 3O1FA 2ZJRW 3CCUW 4CPKA 4YJMA 1NJIX 3W7WA 5JVHW 1VQQA 5GW7A 4WFAW 3CC4W 3OW2V 1VQKW 1MWUA 5GAHa 3O2OA 1JJ2V 1VQ4W 1YITW 3CCMW 1VQNW 5DM7W 1CTFA 1MG9A 1MBVB 4YJXA 3CC2W 1YJWW 1MWSA 1VQLW 3W7XA 1N8RX 3ZFZA 3W7SA 3CCQW 1RQUA 1YJ9W 3CMAW 3O2HA 1QVGV 1YJNW 1MBUC 3PIPW 3O1FB 5M19A 3ZG0A 3CXCV 1VQ8W 3CCLW 3GQ1A 5GAGa 1Q81X 3J7ZZ 2ZJQW 3GW1A 3O2BA 1M90X 1RQVA 1BXYA 3CCVW 3CCRW 5M18A 1VQMW 4C1NA 3CD6W 1KQSV 1R6QC 3CCEW 3CCJW 3G1BA 3G6EW 4DKIA 3W7TA 2W9RA 3DLLW 1VQ6W 4IO9W 1W2BV 5JVGW 3W7UA 1KD1X 1K9MX 1S72W 5GADa 4BL3A 3G71W 3CC7W 5CA3A 1MWRA 4WFBW 1K8AX 1DD3A 1YHQW 1Q86X 1Q82X 1K73X 2WA8A 1DD4A 1VQPW 3DNJA 2WA9A 1KC8X 2ZJPW 4CJNA 1RQSA 2OTLW 3G3PA 4BL2A 3CPWV
chains in the Genus database with same CATH topology
5DM6W 5GAEa 4U67W 4IOAW 2QEXW 3PIOW 1VQ9W 1QVFV 3I56W 5HL7W 4UY8Z 1Q7YX 4WF9W 1VQ5W 1VQ7W 1YIJW 4IOCW 4WCEW 3CF5W 1YI2W 2OTJW 4WFNW 1M1KX 3CCSW 3G4SW 1VQOW 3CMEW 2QA4W 3I55W 2ZJRW 5JVHW 3CCUW 1NJIX 4WFAW 3CC4W 3OW2V 1VQKW 5GAHa 1JJ2V 1VQ4W 1YITW 3CCMW 1VQNW 5DM7W 3CC2W 1YJWW 1VQLW 1N8RX 3CCQW 1YJ9W 3CMAW 1QVGV 1YJNW 3PIPW 3CXCV 1VQ8W 3CCLW 5GAGa 1Q81X 3J7ZZ 2ZJQW 1M90X 1BXYA 3CCVW 3CCRW 1VQMW 4C1NA 3CD6W 1KQSV 3CCEW 3CCJW 3G6EW 3DLLW 1VQ6W 4IO9W 1W2BV 5JVGW 1KD1X 1K9MX 1S72W 5GADa 3G71W 3CC7W 4WFBW 1K8AX 1YHQW 1Q86X 1Q82X 1K73X 1VQPW 1KC8X 2ZJPW 2OTLW 3CPWV
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5DM6 W;  5GAE a;  4U67 W;  4IOA W;  2QEX W;  3PIO W;  1VQ9 W;  1QVF V;  3I56 W;  5HL7 W;  4UY8 Z;  1Q7Y X;  4WF9 W;  1VQ5 W;  1VQ7 W;  1YIJ W;  4IOC W;  4WCE W;  3CF5 W;  1YI2 W;  2OTJ W;  4WFN W;  1M1K X;  3CCS W;  3G4S W;  1VQO W;  3CME W;  2QA4 W;  3I55 W;  2ZJR W;  5JVH W;  3CCU W;  1NJI X;  4WFA W;  3CC4 W;  3OW2 V;  1VQK W;  5GAH a;  1JJ2 V;  1VQ4 W;  1YIT W;  3CCM W;  1VQN W;  5DM7 W;  3CC2 W;  1YJW W;  1VQL W;  1N8R X;  3CCQ W;  1YJ9 W;  3CMA W;  1QVG V;  1YJN W;  3PIP W;  3CXC V;  1VQ8 W;  3CCL W;  5GAG a;  1Q81 X;  3J7Z Z;  2ZJQ W;  1M90 X;  1BXY A;  3CCV W;  3CCR W;  1VQM W;  3CD6 W;  1KQS V;  3CCE W;  3CCJ W;  3G6E W;  3DLL W;  1VQ6 W;  4IO9 W;  1W2B V;  5JVG W;  1KD1 X;  1K9M X;  1S72 W;  5GAD a;  3G71 W;  3CC7 W;  4WFB W;  1K8A X;  1YHQ W;  1Q86 X;  1Q82 X;  1K73 X;  1VQP W;  1KC8 X;  2ZJP W;  2OTL W;  3CPW V; 
#chains in the Genus database with same CATH topology
 3G19 A;  5DM6 W;  5GAE a;  4U67 W;  4IOA W;  2QEX W;  3PIO W;  1VQ9 W;  1QVF V;  3I56 W;  5M1A A;  5HL7 W;  4UY8 Z;  1MWT A;  1Q7Y X;  1MBX C;  4WF9 W;  1VQ5 W;  1R6O C;  1VQ7 W;  1YIJ W;  4IOC W;  4YKA A;  1LZW A;  4WCE W;  3CF5 W;  1YI2 W;  2OTJ W;  3ZG5 A;  4WFN W;  1M1K X;  3CCS W;  3D3I A;  3G4S W;  1VQO W;  3GQ0 A;  3CME W;  2QA4 W;  3I55 W;  3O1F A;  2ZJR W;  3CCU W;  4CPK A;  4YJM A;  1NJI X;  3W7W A;  5JVH W;  1VQQ A;  5GW7 A;  4WFA W;  3CC4 W;  3OW2 V;  1VQK W;  1MWU A;  5GAH a;  3O2O A;  1JJ2 V;  1VQ4 W;  1YIT W;  3CCM W;  1VQN W;  5DM7 W;  1CTF A;  1MG9 A;  1MBV B;  4YJX A;  3CC2 W;  1YJW W;  1MWS A;  1VQL W;  3W7X A;  1N8R X;  3ZFZ A;  3W7S A;  3CCQ W;  1RQU A;  1YJ9 W;  3CMA W;  3O2H A;  1QVG V;  1YJN W;  1MBU C;  3PIP W;  3O1F B;  5M19 A;  3ZG0 A;  3CXC V;  1VQ8 W;  3CCL W;  3GQ1 A;  5GAG a;  1Q81 X;  3J7Z Z;  2ZJQ W;  3GW1 A;  3O2B A;  1M90 X;  1RQV A;  1BXY A;  3CCV W;  3CCR W;  5M18 A;  1VQM W;  4C1N A;  3CD6 W;  1KQS V;  1R6Q C;  3CCE W;  3CCJ W;  3G1B A;  3G6E W;  4DKI A;  3W7T A;  2W9R A;  3DLL W;  1VQ6 W;  4IO9 W;  1W2B V;  5JVG W;  3W7U A;  1KD1 X;  1K9M X;  1S72 W;  5GAD a;  4BL3 A;  3G71 W;  3CC7 W;  5CA3 A;  1MWR A;  4WFB W;  1K8A X;  1DD3 A;  1YHQ W;  1Q86 X;  1Q82 X;  1K73 X;  2WA8 A;  1DD4 A;  1VQP W;  3DNJ A;  2WA9 A;  1KC8 X;  2ZJP W;  4CJN A;  1RQS A;  2OTL W;  3G3P A;  4BL2 A;  3CPW V; 
#chains in the Genus database with same CATH homology
 5DM6 W;  5GAE a;  4U67 W;  4IOA W;  2QEX W;  3PIO W;  1VQ9 W;  1QVF V;  3I56 W;  5HL7 W;  4UY8 Z;  1Q7Y X;  4WF9 W;  1VQ5 W;  1VQ7 W;  1YIJ W;  4IOC W;  4WCE W;  3CF5 W;  1YI2 W;  2OTJ W;  4WFN W;  1M1K X;  3CCS W;  3G4S W;  1VQO W;  3CME W;  2QA4 W;  3I55 W;  2ZJR W;  5JVH W;  3CCU W;  1NJI X;  4WFA W;  3CC4 W;  3OW2 V;  1VQK W;  5GAH a;  1JJ2 V;  1VQ4 W;  1YIT W;  3CCM W;  1VQN W;  5DM7 W;  3CC2 W;  1YJW W;  1VQL W;  1N8R X;  3CCQ W;  1YJ9 W;  3CMA W;  1QVG V;  1YJN W;  3PIP W;  3CXC V;  1VQ8 W;  3CCL W;  5GAG a;  1Q81 X;  3J7Z Z;  2ZJQ W;  1M90 X;  1BXY A;  3CCV W;  3CCR W;  1VQM W;  4C1N A;  3CD6 W;  1KQS V;  3CCE W;  3CCJ W;  3G6E W;  3DLL W;  1VQ6 W;  4IO9 W;  1W2B V;  5JVG W;  1KD1 X;  1K9M X;  1S72 W;  5GAD a;  3G71 W;  3CC7 W;  4WFB W;  1K8A X;  1YHQ W;  1Q86 X;  1Q82 X;  1K73 X;  1VQP W;  1KC8 X;  2ZJP W;  2OTL W;  3CPW V; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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