3CJCD

Actin dimer cross-linked by v. cholerae martx toxin and complexed with dnase i and gelsolin-segment 1
Total Genus 75
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
75
sequence length
260
structure length
258
Chain Sequence
LKIAAFNIRTFGETKMSNATLASYIVRIVRRYDIVLIQEVRDSHLVAVGKLLDYLNQDDPNTYHYVVSEPLGRNSYKERYLFLFRPNKVSVLDTYQYDDGCCGNDSFSREPAVVKFSSHSTKVKEFAIVALHSAPSDAVAEINSLYDVYLDVQQKWHLNDVMLMGDFNADCSYVTSSQWSSIRLRTSSTFQWLIPDSADTTATSTNCAYDRIVVAGSLLQSSVVPGSAAPFDFQAAYGLSNEMALAISDHYPVEVTLT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Connecting actin monomers by iso-peptide bond is a toxicity mechanism of the Vibrio cholerae MARTX toxin.
pubmed doi rcsb
molecule tags Structural protein/hydrolase
source organism Homo sapiens
molecule keywords Actin, alpha skeletal muscle
total genus 75
structure length 258
sequence length 260
ec nomenclature ec 3.1.21.1: Deoxyribonuclease I.
pdb deposition date 2008-03-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF03372 Exo_endo_phos Endonuclease/Exonuclease/phosphatase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.10.10 Alpha Beta 4-Layer Sandwich Deoxyribonuclease I; Chain A Endonuclease/exonuclease/phosphatase 3cjcD00
3W2YA 1AKOA 4FPVA 4GZ2A 5INMA 5A7JA 2DDRA 5INKA 2O3HA 2V0RA 2F1NA 3NGQA 3NGNA 4LNDA 4FVAA 5DV4A 4B5GA 2A3ZB 2UYRX 4B5HA 5DFFA 3G0AA 3G3CA 3N9VA 4QHDA 4L20A 2O3CA 5INNA 4RUWA 1WDUA 2JC5A 5DV2A 4C1RA 5INQA 3G1KA 4A9CA 5J3ZA 5CFGA 4K6LF 3G91A 1DEWA 3G38A 3CJCD 1VYBA 2J63A 3G2CA 3I41A 5EWTA 4PUQA 4QH9A 1YJHA 3NGOA 5J3PA 5J8NA 2DDTA 4GZ0A 5HT2A 5DG0A 3G8VA 4JG3A 2D1KB 5DFIA 3I5VA 2IMQX 3G3YA 3MTCA 3TEBA 3I48A 2DDSA 1Y21A 4B5MA 4F1HA 5J3SA 3GA6A 2JC4A 3DNIA 3MPRA 4IEMA 5A7IA 2VOAA 4B5IA 1ZWXA 5DFHA 4CMNA 4F1IA 3G2DA 4L1ZA 4B5FA 3FZIA 1NTFA 4GYZA 1E9NA 4GZ1A 1HD7A 3G00A 2ISIA 2F2FB 3WCXA 1DE8A 5INLA 1I9YA 2A40B 3L1WA 2EI9A 4CMLA 3U8UA 1BIXA 1DE9A 2A41B 5INOA 4AWNA 4QHEA 3K55A 3W2XA 4L1YA 3NR8A 5J42A 3G4TA 1ATND 1DNKA 3I46A 1SI6X 4B5JA 4F1RA 4F1HB 5DFJA 3W3DB 2V0SA 3G6SA 4L21A 5CFEA 2A42B 5INPA 1SR4B 4GEWA 1I9ZA 2XSWA 2DNJA 3G0RA
chains in the Genus database with same CATH superfamily
3W2YA 1AKOA 4FPVA 4GZ2A 5INMA 5A7JA 2DDRA 5INKA 2O3HA 2V0RA 2F1NA 3NGQA 3NGNA 4LNDA 4FVAA 5DV4A 4B5GA 2A3ZB 2UYRX 4B5HA 5DFFA 3G0AA 3G3CA 3N9VA 4QHDA 4L20A 2O3CA 5INNA 4RUWA 1WDUA 2JC5A 5DV2A 4C1RA 5INQA 3G1KA 4A9CA 5J3ZA 5CFGA 4K6LF 3G91A 1DEWA 3G38A 3CJCD 1VYBA 2J63A 3G2CA 3I41A 5EWTA 4PUQA 4QH9A 1YJHA 3NGOA 5J3PA 5J8NA 2DDTA 4GZ0A 5HT2A 5DG0A 3G8VA 4JG3A 2D1KB 5DFIA 3I5VA 2IMQX 3G3YA 3MTCA 3TEBA 3I48A 2DDSA 1Y21A 4B5MA 4F1HA 5J3SA 3GA6A 2JC4A 3DNIA 3MPRA 4IEMA 5A7IA 2VOAA 4B5IA 1ZWXA 5DFHA 4CMNA 4F1IA 3G2DA 4L1ZA 4B5FA 3FZIA 1NTFA 4GYZA 1E9NA 4GZ1A 1HD7A 3G00A 2ISIA 2F2FB 3WCXA 1DE8A 5INLA 1I9YA 2A40B 3L1WA 2EI9A 4CMLA 3U8UA 1BIXA 1DE9A 2A41B 5INOA 4AWNA 4QHEA 3K55A 3W2XA 4L1YA 3NR8A 5J42A 3G4TA 1ATND 1DNKA 3I46A 1SI6X 4B5JA 4F1RA 4F1HB 5DFJA 3W3DB 2V0SA 3G6SA 4L21A 5CFEA 2A42B 5INPA 1SR4B 4GEWA 1I9ZA 2XSWA 2DNJA 3G0RA
chains in the Genus database with same CATH topology
3W2YA 1AKOA 4FPVA 4GZ2A 5INMA 5A7JA 2DDRA 5INKA 2O3HA 2V0RA 2F1NA 3NGQA 3NGNA 4LNDA 4FVAA 5DV4A 4B5GA 2A3ZB 2UYRX 4B5HA 5DFFA 3G0AA 3G3CA 3N9VA 4QHDA 4L20A 2O3CA 5INNA 4RUWA 1WDUA 2JC5A 5DV2A 4C1RA 5INQA 3G1KA 4A9CA 5J3ZA 5CFGA 4K6LF 3G91A 1DEWA 3G38A 3CJCD 1VYBA 2J63A 3G2CA 3I41A 5EWTA 4PUQA 4QH9A 1YJHA 3NGOA 5J3PA 5J8NA 2DDTA 4GZ0A 5HT2A 5DG0A 3G8VA 4JG3A 2D1KB 5DFIA 3I5VA 2IMQX 3G3YA 3MTCA 3TEBA 3I48A 2DDSA 1Y21A 4B5MA 4F1HA 5J3SA 3GA6A 2JC4A 3DNIA 3MPRA 4IEMA 5A7IA 2VOAA 4B5IA 1ZWXA 5DFHA 4CMNA 4F1IA 3G2DA 4L1ZA 4B5FA 3FZIA 1NTFA 4GYZA 1E9NA 4GZ1A 1HD7A 3G00A 2ISIA 2F2FB 3WCXA 1DE8A 5INLA 1I9YA 2A40B 3L1WA 2EI9A 4CMLA 3U8UA 1BIXA 1DE9A 2A41B 5INOA 4AWNA 4QHEA 3K55A 3W2XA 4L1YA 3NR8A 5J42A 3G4TA 1ATND 1DNKA 3I46A 1SI6X 4B5JA 4F1RA 4F1HB 5DFJA 3W3DB 2V0SA 3G6SA 4L21A 5CFEA 2A42B 5INPA 1SR4B 4GEWA 1I9ZA 2XSWA 2DNJA 3G0RA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3W2Y A;  1AKO A;  4FPV A;  4GZ2 A;  5INM A;  5A7J A;  2DDR A;  5INK A;  2O3H A;  2V0R A;  2F1N A;  3NGQ A;  3NGN A;  4LND A;  4FVA A;  5DV4 A;  4B5G A;  2A3Z B;  2UYR X;  4B5H A;  5DFF A;  3G0A A;  3G3C A;  3N9V A;  4QHD A;  4L20 A;  2O3C A;  5INN A;  4RUW A;  1WDU A;  2JC5 A;  5DV2 A;  4C1R A;  5INQ A;  3G1K A;  4A9C A;  5J3Z A;  5CFG A;  4K6L F;  3G91 A;  1DEW A;  3G38 A;  3CJC D;  1VYB A;  2J63 A;  3G2C A;  3I41 A;  5EWT A;  4PUQ A;  4QH9 A;  1YJH A;  3NGO A;  5J3P A;  5J8N A;  2DDT A;  4GZ0 A;  5HT2 A;  5DG0 A;  3G8V A;  4JG3 A;  2D1K B;  5DFI A;  3I5V A;  2IMQ X;  3G3Y A;  3MTC A;  3TEB A;  3I48 A;  2DDS A;  1Y21 A;  4B5M A;  4F1H A;  5J3S A;  3GA6 A;  2JC4 A;  3DNI A;  3MPR A;  4IEM A;  5A7I A;  2VOA A;  4B5I A;  1ZWX A;  5DFH A;  4CMN A;  4F1I A;  3G2D A;  4L1Z A;  4B5F A;  3FZI A;  1NTF A;  4GYZ A;  1E9N A;  4GZ1 A;  1HD7 A;  3G00 A;  2ISI A;  2F2F B;  3WCX A;  1DE8 A;  5INL A;  1I9Y A;  2A40 B;  3L1W A;  2EI9 A;  4CML A;  3U8U A;  1BIX A;  1DE9 A;  2A41 B;  5INO A;  4AWN A;  4QHE A;  3K55 A;  3W2X A;  4L1Y A;  3NR8 A;  5J42 A;  3G4T A;  1ATN D;  1DNK A;  3I46 A;  1SI6 X;  4B5J A;  4F1R A;  4F1H B;  5DFJ A;  3W3D B;  2V0S A;  3G6S A;  4L21 A;  5CFE A;  2A42 B;  5INP A;  1SR4 B;  4GEW A;  1I9Z A;  2XSW A;  2DNJ A;  3G0R A; 
#chains in the Genus database with same CATH topology
 3W2Y A;  1AKO A;  4FPV A;  4GZ2 A;  5INM A;  5A7J A;  2DDR A;  5INK A;  2O3H A;  2V0R A;  2F1N A;  3NGQ A;  3NGN A;  4LND A;  4FVA A;  5DV4 A;  4B5G A;  2A3Z B;  2UYR X;  4B5H A;  5DFF A;  3G0A A;  3G3C A;  3N9V A;  4QHD A;  4L20 A;  2O3C A;  5INN A;  4RUW A;  1WDU A;  2JC5 A;  5DV2 A;  4C1R A;  5INQ A;  3G1K A;  4A9C A;  5J3Z A;  5CFG A;  4K6L F;  3G91 A;  1DEW A;  3G38 A;  3CJC D;  1VYB A;  2J63 A;  3G2C A;  3I41 A;  5EWT A;  4PUQ A;  4QH9 A;  1YJH A;  3NGO A;  5J3P A;  5J8N A;  2DDT A;  4GZ0 A;  5HT2 A;  5DG0 A;  3G8V A;  4JG3 A;  2D1K B;  5DFI A;  3I5V A;  2IMQ X;  3G3Y A;  3MTC A;  3TEB A;  3I48 A;  2DDS A;  1Y21 A;  4B5M A;  4F1H A;  5J3S A;  3GA6 A;  2JC4 A;  3DNI A;  3MPR A;  4IEM A;  5A7I A;  2VOA A;  4B5I A;  1ZWX A;  5DFH A;  4CMN A;  4F1I A;  3G2D A;  4L1Z A;  4B5F A;  3FZI A;  1NTF A;  4GYZ A;  1E9N A;  4GZ1 A;  1HD7 A;  3G00 A;  2ISI A;  2F2F B;  3WCX A;  1DE8 A;  5INL A;  1I9Y A;  2A40 B;  3L1W A;  2EI9 A;  4CML A;  3U8U A;  1BIX A;  1DE9 A;  2A41 B;  5INO A;  4AWN A;  4QHE A;  3K55 A;  3W2X A;  4L1Y A;  3NR8 A;  5J42 A;  3G4T A;  1ATN D;  1DNK A;  3I46 A;  1SI6 X;  4B5J A;  4F1R A;  4F1H B;  5DFJ A;  3W3D B;  2V0S A;  3G6S A;  4L21 A;  5CFE A;  2A42 B;  5INP A;  1SR4 B;  4GEW A;  1I9Z A;  2XSW A;  2DNJ A;  3G0R A; 
#chains in the Genus database with same CATH homology
 3W2Y A;  1AKO A;  4FPV A;  4GZ2 A;  5INM A;  5A7J A;  2DDR A;  5INK A;  2O3H A;  2V0R A;  2F1N A;  3NGQ A;  3NGN A;  4LND A;  4FVA A;  5DV4 A;  4B5G A;  2A3Z B;  2UYR X;  4B5H A;  5DFF A;  3G0A A;  3G3C A;  3N9V A;  4QHD A;  4L20 A;  2O3C A;  5INN A;  4RUW A;  1WDU A;  2JC5 A;  5DV2 A;  4C1R A;  5INQ A;  3G1K A;  4A9C A;  5J3Z A;  5CFG A;  4K6L F;  3G91 A;  1DEW A;  3G38 A;  3CJC D;  1VYB A;  2J63 A;  3G2C A;  3I41 A;  5EWT A;  4PUQ A;  4QH9 A;  1YJH A;  3NGO A;  5J3P A;  5J8N A;  2DDT A;  4GZ0 A;  5HT2 A;  5DG0 A;  3G8V A;  4JG3 A;  2D1K B;  5DFI A;  3I5V A;  2IMQ X;  3G3Y A;  3MTC A;  3TEB A;  3I48 A;  2DDS A;  1Y21 A;  4B5M A;  4F1H A;  5J3S A;  3GA6 A;  2JC4 A;  3DNI A;  3MPR A;  4IEM A;  5A7I A;  2VOA A;  4B5I A;  1ZWX A;  5DFH A;  4CMN A;  4F1I A;  3G2D A;  4L1Z A;  4B5F A;  3FZI A;  1NTF A;  4GYZ A;  1E9N A;  4GZ1 A;  1HD7 A;  3G00 A;  2ISI A;  2F2F B;  3WCX A;  1DE8 A;  5INL A;  1I9Y A;  2A40 B;  3L1W A;  2EI9 A;  4CML A;  3U8U A;  1BIX A;  1DE9 A;  2A41 B;  5INO A;  4AWN A;  4QHE A;  3K55 A;  3W2X A;  4L1Y A;  3NR8 A;  5J42 A;  3G4T A;  1ATN D;  1DNK A;  3I46 A;  1SI6 X;  4B5J A;  4F1R A;  4F1H B;  5DFJ A;  3W3D B;  2V0S A;  3G6S A;  4L21 A;  5CFE A;  2A42 B;  5INP A;  1SR4 B;  4GEW A;  1I9Z A;  2XSW A;  2DNJ A;  3G0R A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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