3CJCG

Actin dimer cross-linked by v. cholerae martx toxin and complexed with dnase i and gelsolin-segment 1
Total Genus 30
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
30
sequence length
125
structure length
125
Chain Sequence
MVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Connecting actin monomers by iso-peptide bond is a toxicity mechanism of the Vibrio cholerae MARTX toxin.
pubmed doi rcsb
molecule tags Structural protein/hydrolase
source organism Homo sapiens
molecule keywords Actin, alpha skeletal muscle
total genus 30
structure length 125
sequence length 125
ec nomenclature
pdb deposition date 2008-03-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
G PF00626 Gelsolin Gelsolin repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 3cjcG00
5KYXB 1YVNG 1M4JA 1T3XA 2VACA 5KYYA 3CJCG 5IVUA 2D8BA 1TMWA 1WNJA 2LJ8A 1COFA 3FFKA 5A1MA 3DAWB 2LLFA 3A5LS 1M2VA 2XF1A 3A5OS 3CJBG 5DD2A 5HVKB 1C0FS 3TU5B 1RGIG 4KEEA 4Z94G 1D4XG 4KEDA 3EGDB 4PKHB 5KYUA 5KYWB 1SVRA 4PKIG 2HD7A 2LXXA 3CI5G 3EGXA 5FAEA 1WM4A 4CBWG 1PD1A 2MV2A 3EG9A 1MDUA 1AHQA 2NUPA 5KYXA 3FG7A 2FF6G 1X67A 1M2OA 1NM1G 1P8XA 1VKKA 2FH1A 2FF3A 1C0GS 5KYYB 2KVKA 5L6WC 1P8ZG 4S10C 3CIPG 3Q2BA 2NUTA 1T2LA 4CBUG 1CNUA 1Q8GA 1UDMA 1F7SA 3L50A 4LIZA 2XFAA 1T3YA 3EFOB 1NPHA 2FH4A 5KYNA 1NLVG 1J72A 1ESVS 1VFQA 5KYWA 1V6FA 1QPVA 3EH1A 1H1VG 3FG6A 3FFNA 2MP4A 1AK7A 1AK6A 1TVJA 3EH2A 1NMDG 4BEX1 1CFYA 2W0IA 2I2QA 1PCXA 2VIKA 2NUPB 4JD2H 1DEJS 1SVQA 5FAFA 4KEFA 2VILA 2FH3A 3A5NS 1M2VB 3A5MS 2FH2A 1JHWA 4PKGG 2FGHA 2QTVA 2NUTB 3EGDA 1WFSA 5KYUB 3EFOA 4CBXG 3EGXB 1PD0A 1YAGG 1D0NA 1T44G 3EG9B 1KCQA 1EQYS 1HQZ1 1SVYA 2MOTA 5HVKD 2L72A 1Q8XA
chains in the Genus database with same CATH superfamily
5KYXB 1YVNG 1M4JA 1T3XA 2VACA 5KYYA 3CJCG 5IVUA 2D8BA 1TMWA 1WNJA 2LJ8A 1COFA 3FFKA 5A1MA 3DAWB 2LLFA 3A5LS 1M2VA 2XF1A 3A5OS 3CJBG 5DD2A 5HVKB 1C0FS 3TU5B 1RGIG 4KEEA 4Z94G 1D4XG 4KEDA 3EGDB 4PKHB 5KYUA 5KYWB 1SVRA 4PKIG 2HD7A 2LXXA 3CI5G 3EGXA 5FAEA 1WM4A 4CBWG 1PD1A 2MV2A 3EG9A 1MDUA 1AHQA 2NUPA 5KYXA 3FG7A 2FF6G 1X67A 1M2OA 1NM1G 1P8XA 1VKKA 2FH1A 2FF3A 1C0GS 5KYYB 2KVKA 5L6WC 1P8ZG 4S10C 3CIPG 3Q2BA 2NUTA 1T2LA 4CBUG 1CNUA 1Q8GA 1UDMA 1F7SA 3L50A 4LIZA 2XFAA 1T3YA 3EFOB 1NPHA 2FH4A 5KYNA 1NLVG 1J72A 1ESVS 1VFQA 5KYWA 1V6FA 1QPVA 3EH1A 1H1VG 3FG6A 3FFNA 2MP4A 1AK7A 1AK6A 1TVJA 3EH2A 1NMDG 4BEX1 1CFYA 2W0IA 2I2QA 1PCXA 2VIKA 2NUPB 4JD2H 1DEJS 1SVQA 5FAFA 4KEFA 2VILA 2FH3A 3A5NS 1M2VB 3A5MS 2FH2A 1JHWA 4PKGG 2FGHA 2QTVA 2NUTB 3EGDA 1WFSA 5KYUB 3EFOA 4CBXG 3EGXB 1PD0A 1YAGG 3DA7A 1D0NA 1T44G 3EG9B 1KCQA 1EQYS 1HQZ1 1SVYA 2MOTA 5HVKD 2L72A 1Q8XA
chains in the Genus database with same CATH topology
5KYXB 1YVNG 1M4JA 1T3XA 2VACA 5KYYA 3CJCG 5IVUA 2D8BA 1TMWA 1WNJA 2LJ8A 1COFA 3FFKA 5A1MA 3DAWB 2LLFA 3A5LS 1M2VA 2XF1A 3A5OS 3CJBG 5DD2A 5HVKB 1C0FS 3TU5B 1RGIG 4KEEA 4Z94G 1D4XG 4KEDA 3EGDB 4PKHB 5KYUA 5KYWB 1SVRA 4PKIG 2HD7A 2LXXA 3CI5G 3EGXA 5FAEA 1WM4A 4CBWG 1PD1A 2MV2A 3EG9A 1MDUA 1AHQA 2NUPA 5KYXA 3FG7A 2FF6G 1X67A 1M2OA 1NM1G 1P8XA 1VKKA 2FH1A 2FF3A 1C0GS 5KYYB 2KVKA 5L6WC 1P8ZG 4S10C 3CIPG 3Q2BA 2NUTA 1T2LA 4CBUG 1CNUA 1Q8GA 1UDMA 1F7SA 3L50A 4LIZA 2XFAA 1T3YA 3EFOB 1NPHA 2FH4A 5KYNA 1NLVG 1J72A 1ESVS 1VFQA 5KYWA 1V6FA 1QPVA 3EH1A 1H1VG 3FG6A 3FFNA 2MP4A 1AK7A 1AK6A 1TVJA 3EH2A 1NMDG 4BEX1 1CFYA 2W0IA 2I2QA 1PCXA 2VIKA 2NUPB 4JD2H 1DEJS 1SVQA 5FAFA 4KEFA 2VILA 2FH3A 3A5NS 1M2VB 3A5MS 2FH2A 1JHWA 4PKGG 2FGHA 2QTVA 2NUTB 3EGDA 1WFSA 5KYUB 3EFOA 4CBXG 3EGXB 1PD0A 1YAGG 3DA7A 1D0NA 1T44G 3EG9B 1KCQA 1EQYS 1HQZ1 1SVYA 2MOTA 5HVKD 2L72A 1Q8XA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5KYX B;  1YVN G;  1M4J A;  1T3X A;  2VAC A;  5KYY A;  3CJC G;  5IVU A;  2D8B A;  1TMW A;  1WNJ A;  2LJ8 A;  1COF A;  3FFK A;  5A1M A;  3DAW B;  2LLF A;  3A5L S;  1M2V A;  2XF1 A;  3A5O S;  3CJB G;  5DD2 A;  5HVK B;  1C0F S;  3TU5 B;  1RGI G;  4KEE A;  4Z94 G;  1D4X G;  4KED A;  3EGD B;  4PKH B;  5KYU A;  5KYW B;  1SVR A;  4PKI G;  2HD7 A;  2LXX A;  3CI5 G;  3EGX A;  5FAE A;  1WM4 A;  4CBW G;  1PD1 A;  2MV2 A;  3EG9 A;  1MDU A;  1AHQ A;  2NUP A;  5KYX A;  3FG7 A;  2FF6 G;  1X67 A;  1M2O A;  1NM1 G;  1P8X A;  1VKK A;  2FH1 A;  2FF3 A;  1C0G S;  5KYY B;  2KVK A;  5L6W C;  1P8Z G;  4S10 C;  3CIP G;  3Q2B A;  2NUT A;  1T2L A;  4CBU G;  1CNU A;  1Q8G A;  1UDM A;  1F7S A;  3L50 A;  4LIZ A;  2XFA A;  1T3Y A;  3EFO B;  1NPH A;  2FH4 A;  5KYN A;  1NLV G;  1J72 A;  1ESV S;  1VFQ A;  5KYW A;  1V6F A;  1QPV A;  3EH1 A;  1H1V G;  3FG6 A;  3FFN A;  2MP4 A;  1AK7 A;  1AK6 A;  1TVJ A;  3EH2 A;  1NMD G;  4BEX 1;  1CFY A;  2W0I A;  2I2Q A;  1PCX A;  2VIK A;  2NUP B;  4JD2 H;  1DEJ S;  1SVQ A;  5FAF A;  4KEF A;  2VIL A;  2FH3 A;  3A5N S;  1M2V B;  3A5M S;  2FH2 A;  1JHW A;  4PKG G;  2FGH A;  2QTV A;  2NUT B;  3EGD A;  1WFS A;  5KYU B;  3EFO A;  4CBX G;  3EGX B;  1PD0 A;  1YAG G;  1D0N A;  1T44 G;  3EG9 B;  1KCQ A;  1EQY S;  1HQZ 1;  1SVY A;  2MOT A;  5HVK D;  2L72 A;  1Q8X A; 
#chains in the Genus database with same CATH topology
 5KYX B;  1YVN G;  1M4J A;  1T3X A;  2VAC A;  5KYY A;  3CJC G;  5IVU A;  2D8B A;  1TMW A;  1WNJ A;  2LJ8 A;  1COF A;  3FFK A;  5A1M A;  3DAW B;  2LLF A;  3A5L S;  1M2V A;  2XF1 A;  3A5O S;  3CJB G;  5DD2 A;  5HVK B;  1C0F S;  3TU5 B;  1RGI G;  4KEE A;  4Z94 G;  1D4X G;  4KED A;  3EGD B;  4PKH B;  5KYU A;  5KYW B;  1SVR A;  4PKI G;  2HD7 A;  2LXX A;  3CI5 G;  3EGX A;  5FAE A;  1WM4 A;  4CBW G;  1PD1 A;  2MV2 A;  3EG9 A;  1MDU A;  1AHQ A;  2NUP A;  5KYX A;  3FG7 A;  2FF6 G;  1X67 A;  1M2O A;  1NM1 G;  1P8X A;  1VKK A;  2FH1 A;  2FF3 A;  1C0G S;  5KYY B;  2KVK A;  5L6W C;  1P8Z G;  4S10 C;  3CIP G;  3Q2B A;  2NUT A;  1T2L A;  4CBU G;  1CNU A;  1Q8G A;  1UDM A;  1F7S A;  3L50 A;  4LIZ A;  2XFA A;  1T3Y A;  3EFO B;  1NPH A;  2FH4 A;  5KYN A;  1NLV G;  1J72 A;  1ESV S;  1VFQ A;  5KYW A;  1V6F A;  1QPV A;  3EH1 A;  1H1V G;  3FG6 A;  3FFN A;  2MP4 A;  1AK7 A;  1AK6 A;  1TVJ A;  3EH2 A;  1NMD G;  4BEX 1;  1CFY A;  2W0I A;  2I2Q A;  1PCX A;  2VIK A;  2NUP B;  4JD2 H;  1DEJ S;  1SVQ A;  5FAF A;  4KEF A;  2VIL A;  2FH3 A;  3A5N S;  1M2V B;  3A5M S;  2FH2 A;  1JHW A;  4PKG G;  2FGH A;  2QTV A;  2NUT B;  3EGD A;  1WFS A;  5KYU B;  3EFO A;  4CBX G;  3EGX B;  1PD0 A;  1YAG G;  3DA7 A;  1D0N A;  1T44 G;  3EG9 B;  1KCQ A;  1EQY S;  1HQZ 1;  1SVY A;  2MOT A;  5HVK D;  2L72 A;  1Q8X A; 
#chains in the Genus database with same CATH homology
 5KYX B;  1YVN G;  1M4J A;  1T3X A;  2VAC A;  5KYY A;  3CJC G;  5IVU A;  2D8B A;  1TMW A;  1WNJ A;  2LJ8 A;  1COF A;  3FFK A;  5A1M A;  3DAW B;  2LLF A;  3A5L S;  1M2V A;  2XF1 A;  3A5O S;  3CJB G;  5DD2 A;  5HVK B;  1C0F S;  3TU5 B;  1RGI G;  4KEE A;  4Z94 G;  1D4X G;  4KED A;  3EGD B;  4PKH B;  5KYU A;  5KYW B;  1SVR A;  4PKI G;  2HD7 A;  2LXX A;  3CI5 G;  3EGX A;  5FAE A;  1WM4 A;  4CBW G;  1PD1 A;  2MV2 A;  3EG9 A;  1MDU A;  1AHQ A;  2NUP A;  5KYX A;  3FG7 A;  2FF6 G;  1X67 A;  1M2O A;  1NM1 G;  1P8X A;  1VKK A;  2FH1 A;  2FF3 A;  1C0G S;  5KYY B;  2KVK A;  5L6W C;  1P8Z G;  4S10 C;  3CIP G;  3Q2B A;  2NUT A;  1T2L A;  4CBU G;  1CNU A;  1Q8G A;  1UDM A;  1F7S A;  3L50 A;  4LIZ A;  2XFA A;  1T3Y A;  3EFO B;  1NPH A;  2FH4 A;  5KYN A;  1NLV G;  1J72 A;  1ESV S;  1VFQ A;  5KYW A;  1V6F A;  1QPV A;  3EH1 A;  1H1V G;  3FG6 A;  3FFN A;  2MP4 A;  1AK7 A;  1AK6 A;  1TVJ A;  3EH2 A;  1NMD G;  4BEX 1;  1CFY A;  2W0I A;  2I2Q A;  1PCX A;  2VIK A;  2NUP B;  4JD2 H;  1DEJ S;  1SVQ A;  5FAF A;  4KEF A;  2VIL A;  2FH3 A;  3A5N S;  1M2V B;  3A5M S;  2FH2 A;  1JHW A;  4PKG G;  2FGH A;  2QTV A;  2NUT B;  3EGD A;  1WFS A;  5KYU B;  3EFO A;  4CBX G;  3EGX B;  1PD0 A;  1YAG G;  3DA7 A;  1D0N A;  1T44 G;  3EG9 B;  1KCQ A;  1EQY S;  1HQZ 1;  1SVY A;  2MOT A;  5HVK D;  2L72 A;  1Q8X A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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