3CP6A

Crystal structure of human farnesyl diphosphate synthase (t201a mutant) complexed with mg and biphosphonate inhibitor
Total Genus 128
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
128
sequence length
338
structure length
334
Chain Sequence
AQEKQDFVQHFSQIVRVLTEHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKAAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKI
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Human farnesyl diphosphate synthase (T201A mutant) complexed with Mg and biphosphonate inhibitor.
rcsb
molecule keywords Farnesyl pyrophosphate synthetase
molecule tags Transferase
source organism Homo sapiens
total genus 128
structure length 334
sequence length 338
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2008-03-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 3cp6A00
3WCMA 3P5RA 3TC1A 3EGTA 5AHUB 1JFGA 5JV0F 4WK5A 1HXGA 3N0GA 4K10A 3QKCA 5IK0A 3LGKA 4F6VA 4NFIF 5IK6A 5JUZF 3OACB 1YYTA 2E4OA 4DXJA 1FPSA 2F8ZF 3NRIA 4JYXA 3KBKA 2OA6A 1ZW5A 3RYEA 4KPDA 4RXCA 5ERNA 3PDEA 2Z4WA 3Q1OA 4KQ5A 2E93A 3Q30A 2O1OA 3TFNA 2PS6A 3ICZA 2E8WA 4JZBA 1RQIA 4EA2A 1VG7A 3QQVA 2Z78A 3Q2ZA 3KRCB 5JA0F 3KRPB 5EATA 2ZCQA 1YV5A 3N46F 1YYSA 3N1WF 3KRPA 3VJCA 5KSXF 3SDVA 3S9VA 4NFKF 5A0JA 1N1BA 2ZCSA 4E9UA 3MZVA 5ILZA 5IKAA 3TS7A 3M01A 2Q9YA 3ACYA 3N5HF 2E92A 2AZLA 3VJ9A 3TFVA 3WC9A 5EASA 3ZMBA 5B0JA 1UBXA 2RAHA 4KPJA 3KB9A 2E91A 5ERMA 4H5EF 4OMHA 5ILYA 3WCAA 4NKEA 4DZWA 1YHMA 5AFXA 3ACWA 1VG2A 3ICMA 4RXAA 3P8RA 5EAUA 1V4HA 3LJIA 3M00A 2F94F 4QXSF 4LTZA 4XQRF 5B02A 4RXDA 2E8XA 1V4JA 3NF2A 5HN8A 1VG3A 3LLWA 4LFEA 3SDUA 3ZOUA 3VJEA 3V1XA 5IN8A 1RQJA 4HD1A 1WKZA 2ONGA 4GP1A 2F89F 5HN7A 3ZL6A 2F92F 3IPIA 5JV2F 3PH7A 4LZ0A 2AZKA 3APZA 2H8OA 3WJNA 3WJOA 3LOMA 4FJQA 3DYHA 4KWDA 2AETA 3AQCB 3SAEA 3TFPA 4MC3A 3WCIA 4JZXA 3LG5A 1PS1A 5B01A 5IMIA 4LA5A 1WL1A 2Z4ZA 3N3LF 3OACA 3NPRA 2P1CA 4ZQ8A 5B0KA 5ILKA 3KRFB 5CG6A 4F62A 5A0IA 2E90A 5IMNA 3WEJA 3ICNA 3WCGA 5ILDA 1V4KA 4P0XA 5IL8A 3WCDA 1UBWA 4LZ3A 4XQTF 4RNQA 4Q23A 3N6KF 3V1VA 2J5CA 4LFVF 3G4DA 2OPNA 1RTRA 3P8LA 2AELA 3KRCA 2PS8A 2FORA 4LTVA 3CKEA 4N9UA 1YHLA 5ILJA 4E1EA 2Z50A 1HX9A 4JVJF 4OKZA 3M9UA 4MC0A 3VJDA 3CP6A 3EZ3A 2DH4A 4OKMA 3ID0A 2E8UA 1N21A 5ILIA 3CC9A 1HXCA 1WL0A 2F7MF 3N1VF 4MC8A 4N1ZF 4KFAA 3N3DA 4NUAA 1EZFA 3AQBB 4PVYF 5E8HA 3WEIA 3ADZA 2PS7A 2ZY1A 2E94A 4NG6A 3V66A 2AZJA 5C05A 3SDQA 1N20A 5A0KA 5B0MA 3WCJA 3P5PA 3LZ9A 3Q2QA 1V4EA 3VJBA 5DGSF 5E8LA 5AYPA 1JFAA 1WY0A 4QPFA 1YQ7A 3NPKA 4H5DF 4L2XF 5IKHA 3VJAA 1YJ4A 3KRAB 3WCLA 2J1OA 4JXYA 4GAXA 3SDRA 3DYGA 5DGNF 3ICKA 3WCFA 1WL3A 3KRAA 1HXAA 2I19A 4KKMA 4DI5A 2Z7HA 1YYQA 4KVIA 3ASXA 3OYRA 3N49F 1HM4A 3N45F 3SDTA 1N22A 4F6XA 3P41A 1KIZA 4RXEA 1VG6A 1VG4A 4LPGF 4LLTA 3WSBA 5DIQF 5EROA 4EA0A 3LVSA 5IMPA 2ZEUA 3N0FA 5B0IA 2PS4A 5DJVF 3WCBA 1N24A 4FP4A 3BNYA 1UBYA 5DJRF 4EA1A 5HNAA 4NKFA 3WEHA 3KRFA 3LGZB 3LMDA 3BNXA 4LIXA 2ONHA 3S4JA 3WSAA 5DW7A 4PVXF 3PYBA 3WEKA 1HM7A 4LOBA 2AEKA 4P0VA 5IK9A 3VJ8A 2E8TA 5DZ2A 3G4FA 3WEGA 3IBAA 3WCEA 2VF6A 3PKOA 3KROB 3DYFA 4P0WA 4KQSA 4KVYA 4OMGA 4KK2A 3EFQA 3LK5A 4DWGA 3OABB 4JXNA 5IVGA 2ZCOA 3KROA 4GP2A 2PS5A 5ILHA 4XQSF 4DHDA 4GA3A 5I1UA 2J1PA 3OABA 5B03A 5IM1A 3LEEA 3LSNA 3WCHA 1DGPA 4UMJA 4LZCA 2Q9ZA 3RBMA 2Z4YA 4KVWA 2QISA 1N23A 5DHIA 3N5JF 5B0LA 4KQUA 3WEFA 2F8CF 2OPMA 5CG5A 2EWGA 1DI1A 2Z7IA 5DGMF 3WE9A 3WCCA 3ZMCA 4DWBA 2Q80A 1N1ZA 1V4IA 3M02A 3RYWA 1WL2A 4LFGA 3RMGA 3PYAA 3ZCDA 3ACXA 4KVDA 5IL3A 3MAVA 1UBVA 3WJKA 5DJPF 2ZCRA 4LLSA 4LPHF 5H9DA 4LXWA 5AELA 4NFJF 3W7FA 3UCAA 2F9KF 3B7LA 1WMWA 1YHKA 2Z4VA 3AE0A 5JV1F 1KIYA 2FTZA 2E8VA 2Z52A 4H5CF 5ER8A 2Q58A 2OGDA 3AQ0A 5HN9A 4RYPA 1YYRA 4LUUA 4E9ZA 5B00A 2ZEVA 4DEMF 1YYUA 2Z4XA 5E8KA 4OGUA 5DHKA 2E95A 3LDWA 4LA6A 3M0GA 4KUXA
chains in the Genus database with same CATH superfamily
3WCMA 3P5RA 3TC1A 3EGTA 5AHUB 1JFGA 5JV0F 4WK5A 1HXGA 3N0GA 4K10A 3QKCA 5IK0A 3LGKA 4F6VA 4NFIF 5IK6A 5JUZF 3OACB 1YYTA 2E4OA 4DXJA 1FPSA 2F8ZF 3NRIA 4JYXA 3KBKA 2OA6A 1ZW5A 3RYEA 4KPDA 4RXCA 5ERNA 3PDEA 2Z4WA 3Q1OA 4KQ5A 2E93A 3Q30A 2O1OA 3TFNA 2PS6A 3ICZA 2E8WA 4JZBA 1RQIA 4EA2A 1VG7A 3QQVA 2Z78A 3Q2ZA 3KRCB 5JA0F 3KRPB 5EATA 2ZCQA 1YV5A 3N46F 1YYSA 3N1WF 3KRPA 3VJCA 5KSXF 3SDVA 3S9VA 4NFKF 5A0JA 1N1BA 2ZCSA 4E9UA 3MZVA 5ILZA 5IKAA 3TS7A 3M01A 2Q9YA 3ACYA 3N5HF 2E92A 2AZLA 3VJ9A 3TFVA 3WC9A 5EASA 3ZMBA 5B0JA 1UBXA 2RAHA 4KPJA 3KB9A 2E91A 5ERMA 4H5EF 4OMHA 5ILYA 3WCAA 4NKEA 4DZWA 1YHMA 5AFXA 3ACWA 1VG2A 3ICMA 4RXAA 3P8RA 5EAUA 1V4HA 3LJIA 3M00A 2F94F 4QXSF 4LTZA 4XQRF 5B02A 4RXDA 2E8XA 1V4JA 3NF2A 5HN8A 1VG3A 3LLWA 4LFEA 3SDUA 3ZOUA 3VJEA 3V1XA 5IN8A 1RQJA 4HD1A 1WKZA 2ONGA 4GP1A 2F89F 5HN7A 3ZL6A 2F92F 3IPIA 5JV2F 3PH7A 4LZ0A 2AZKA 3APZA 2H8OA 3WJNA 3WJOA 3LOMA 4FJQA 3DYHA 4KWDA 2AETA 3AQCB 3SAEA 3TFPA 4MC3A 3WCIA 4JZXA 3LG5A 1PS1A 5B01A 5IMIA 4LA5A 1WL1A 2Z4ZA 3N3LF 3OACA 3NPRA 2P1CA 4ZQ8A 5B0KA 5ILKA 3KRFB 5CG6A 4F62A 5A0IA 2E90A 5IMNA 3WEJA 3ICNA 3WCGA 5ILDA 1V4KA 4P0XA 5IL8A 3WCDA 1UBWA 4LZ3A 4XQTF 4RNQA 4Q23A 3N6KF 3V1VA 2J5CA 4LFVF 3G4DA 2OPNA 1RTRA 3P8LA 2AELA 3KRCA 2PS8A 2FORA 4LTVA 3CKEA 4N9UA 1YHLA 5ILJA 4E1EA 2Z50A 1HX9A 4JVJF 4OKZA 3M9UA 4MC0A 3VJDA 3CP6A 3EZ3A 2DH4A 4OKMA 3ID0A 2E8UA 1N21A 5ILIA 3CC9A 1HXCA 1WL0A 2F7MF 3N1VF 4MC8A 4N1ZF 4KFAA 3N3DA 4NUAA 1EZFA 3AQBB 4PVYF 5E8HA 3WEIA 3ADZA 2PS7A 2ZY1A 2E94A 4NG6A 3V66A 2AZJA 5C05A 3SDQA 1N20A 5A0KA 5B0MA 3WCJA 3P5PA 3LZ9A 3Q2QA 1V4EA 3VJBA 5DGSF 5E8LA 5AYPA 1JFAA 1WY0A 4QPFA 1YQ7A 3NPKA 4H5DF 4L2XF 5IKHA 3VJAA 1YJ4A 3KRAB 3WCLA 2J1OA 4JXYA 4GAXA 3SDRA 3DYGA 5DGNF 3ICKA 3WCFA 1WL3A 3KRAA 1HXAA 2I19A 4KKMA 4DI5A 2Z7HA 1YYQA 4KVIA 3ASXA 3OYRA 3N49F 1HM4A 3N45F 3SDTA 1N22A 4F6XA 3P41A 1KIZA 4RXEA 1VG6A 1VG4A 4LPGF 4LLTA 3WSBA 5DIQF 5EROA 4EA0A 3LVSA 5IMPA 2ZEUA 3N0FA 5B0IA 2PS4A 5DJVF 3WCBA 1N24A 4FP4A 3BNYA 1UBYA 5DJRF 4EA1A 5HNAA 4NKFA 3WEHA 3KRFA 3LGZB 3LMDA 3BNXA 4LIXA 2ONHA 3S4JA 3WSAA 5DW7A 4PVXF 3PYBA 3WEKA 1HM7A 4LOBA 2AEKA 4P0VA 5IK9A 3VJ8A 2E8TA 5DZ2A 3G4FA 3WEGA 3IBAA 3WCEA 2VF6A 3PKOA 3KROB 3DYFA 4P0WA 4KQSA 4KVYA 4OMGA 4KK2A 3EFQA 3LK5A 4DWGA 3OABB 4JXNA 5IVGA 2ZCOA 3KROA 4GP2A 2PS5A 5ILHA 4XQSF 4DHDA 4GA3A 5I1UA 2J1PA 3OABA 5B03A 5IM1A 3LEEA 3LSNA 3WCHA 1DGPA 4UMJA 4LZCA 2Q9ZA 3RBMA 2Z4YA 4KVWA 2QISA 1N23A 5DHIA 3N5JF 5B0LA 4KQUA 3WEFA 2F8CF 2OPMA 5CG5A 2EWGA 1DI1A 2Z7IA 5DGMF 3WE9A 3WCCA 3ZMCA 4DWBA 2Q80A 1N1ZA 1V4IA 3M02A 3RYWA 1WL2A 4LFGA 3RMGA 3PYAA 3ZCDA 3ACXA 4KVDA 5IL3A 3MAVA 1UBVA 3WJKA 5DJPF 2ZCRA 4LLSA 4LPHF 5H9DA 4LXWA 5AELA 4NFJF 3W7FA 3UCAA 2F9KF 3B7LA 1WMWA 1YHKA 2Z4VA 3AE0A 5JV1F 1KIYA 2FTZA 2E8VA 2Z52A 4H5CF 5ER8A 2Q58A 2OGDA 3AQ0A 5HN9A 4RYPA 1YYRA 4LUUA 4E9ZA 5B00A 2ZEVA 4DEMF 1YYUA 2Z4XA 5E8KA 4OGUA 5DHKA 2E95A 3LDWA 4LA6A 3M0GA 4KUXA
chains in the Genus database with same CATH topology
3WCMA 3P5RA 3TC1A 3EGTA 5AHUB 1JFGA 5JV0F 4WK5A 1HXGA 3N0GA 4K10A 3QKCA 5IK0A 3LGKA 4F6VA 4NFIF 5IK6A 5JUZF 3OACB 1YYTA 2E4OA 4DXJA 1FPSA 2F8ZF 3NRIA 4JYXA 3KBKA 2OA6A 1ZW5A 3RYEA 4KPDA 4RXCA 5ERNA 3PDEA 2Z4WA 3Q1OA 4KQ5A 2E93A 3Q30A 2O1OA 3TFNA 2PS6A 3ICZA 2E8WA 4JZBA 1RQIA 4EA2A 1VG7A 3QQVA 2Z78A 3Q2ZA 3KRCB 5JA0F 3KRPB 5EATA 2ZCQA 1YV5A 3N46F 1YYSA 3N1WF 3KRPA 3VJCA 5KSXF 3SDVA 3S9VA 4NFKF 5A0JA 1N1BA 2ZCSA 4E9UA 3MZVA 5ILZA 5IKAA 3TS7A 3M01A 2Q9YA 3ACYA 3N5HF 2E92A 2AZLA 3VJ9A 3TFVA 3WC9A 5EASA 3ZMBA 5B0JA 1UBXA 2RAHA 4KPJA 3KB9A 2E91A 5ERMA 4H5EF 4OMHA 5ILYA 3WCAA 4NKEA 4DZWA 1YHMA 5AFXA 3ACWA 1VG2A 3ICMA 4RXAA 3P8RA 5EAUA 1V4HA 3LJIA 3M00A 2F94F 4QXSF 4LTZA 4XQRF 5B02A 4RXDA 2E8XA 1V4JA 3NF2A 5HN8A 1VG3A 3LLWA 4LFEA 3SDUA 3ZOUA 3VJEA 3V1XA 5IN8A 1RQJA 4HD1A 1WKZA 2ONGA 4GP1A 2F89F 5HN7A 3ZL6A 2F92F 3IPIA 5JV2F 3PH7A 4LZ0A 2AZKA 3APZA 2H8OA 3WJNA 3WJOA 3LOMA 4FJQA 3DYHA 4KWDA 2AETA 3AQCB 3SAEA 3TFPA 4MC3A 3WCIA 4JZXA 3LG5A 1PS1A 5B01A 5IMIA 4LA5A 1WL1A 2Z4ZA 3N3LF 3OACA 3NPRA 2P1CA 4ZQ8A 5B0KA 5ILKA 3KRFB 5CG6A 4F62A 5A0IA 2E90A 5IMNA 3WEJA 3ICNA 3WCGA 5ILDA 1V4KA 4P0XA 5IL8A 3WCDA 1UBWA 4LZ3A 4XQTF 4RNQA 4Q23A 3N6KF 3V1VA 2J5CA 4LFVF 3G4DA 2OPNA 1RTRA 3P8LA 2AELA 3KRCA 2PS8A 2FORA 4LTVA 3CKEA 4N9UA 1YHLA 5ILJA 4E1EA 2Z50A 1HX9A 4JVJF 4OKZA 3M9UA 4MC0A 3VJDA 3CP6A 3EZ3A 2DH4A 4OKMA 3ID0A 2E8UA 1N21A 5ILIA 3CC9A 1HXCA 1WL0A 2F7MF 3N1VF 4MC8A 4N1ZF 4KFAA 3N3DA 4NUAA 1EZFA 3AQBB 4PVYF 5E8HA 3WEIA 3ADZA 2PS7A 2ZY1A 2E94A 4NG6A 3V66A 2AZJA 5C05A 3SDQA 1N20A 5A0KA 5B0MA 3WCJA 3P5PA 3LZ9A 3Q2QA 1V4EA 3VJBA 5DGSF 5E8LA 5AYPA 1JFAA 1WY0A 4QPFA 1YQ7A 3NPKA 4H5DF 4L2XF 5IKHA 3VJAA 1YJ4A 3KRAB 3WCLA 2J1OA 4JXYA 4GAXA 3SDRA 3DYGA 5DGNF 3ICKA 3WCFA 1WL3A 3KRAA 1HXAA 2I19A 4KKMA 4DI5A 2Z7HA 1YYQA 4KVIA 3ASXA 3OYRA 3N49F 1HM4A 3N45F 3SDTA 1N22A 4F6XA 3P41A 1KIZA 4RXEA 1VG6A 1VG4A 4LPGF 4LLTA 3WSBA 5DIQF 5EROA 4EA0A 3LVSA 5IMPA 2ZEUA 3N0FA 5B0IA 2PS4A 5DJVF 3WCBA 1N24A 4FP4A 3BNYA 1UBYA 5DJRF 4EA1A 5HNAA 4NKFA 3WEHA 3KRFA 3LGZB 3LMDA 3BNXA 4LIXA 2ONHA 3S4JA 3WSAA 5DW7A 4PVXF 3PYBA 3WEKA 1HM7A 4LOBA 2AEKA 4P0VA 5IK9A 3VJ8A 2E8TA 5DZ2A 3G4FA 3WEGA 3IBAA 3WCEA 2VF6A 3PKOA 3KROB 3DYFA 4P0WA 4KQSA 4KVYA 4OMGA 4KK2A 3EFQA 3LK5A 4DWGA 3OABB 4JXNA 5IVGA 2ZCOA 3KROA 4GP2A 2PS5A 5ILHA 4XQSF 4DHDA 4GA3A 5I1UA 2J1PA 3OABA 5B03A 5IM1A 3LEEA 3LSNA 3WCHA 1DGPA 4UMJA 4LZCA 2Q9ZA 3RBMA 2Z4YA 4KVWA 2QISA 1N23A 5DHIA 3N5JF 5B0LA 4KQUA 3WEFA 2F8CF 2OPMA 5CG5A 2EWGA 1DI1A 2Z7IA 5DGMF 3WE9A 3WCCA 3ZMCA 4DWBA 2Q80A 1N1ZA 1V4IA 3M02A 3RYWA 1WL2A 4LFGA 3RMGA 3PYAA 3ZCDA 3ACXA 4KVDA 5IL3A 3MAVA 1UBVA 3WJKA 5DJPF 2ZCRA 4LLSA 4LPHF 5H9DA 4LXWA 5AELA 4NFJF 3W7FA 3UCAA 2F9KF 3B7LA 1WMWA 1YHKA 2Z4VA 3AE0A 5JV1F 1KIYA 2FTZA 2E8VA 2Z52A 4H5CF 5ER8A 2Q58A 2OGDA 3AQ0A 5HN9A 4RYPA 1YYRA 4LUUA 4E9ZA 5B00A 2ZEVA 4DEMF 1YYUA 2Z4XA 5E8KA 4OGUA 5DHKA 2E95A 3LDWA 4LA6A 3M0GA 4KUXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3WCM A;  3P5R A;  3TC1 A;  3EGT A;  5AHU B;  1JFG A;  5JV0 F;  4WK5 A;  1HXG A;  3N0G A;  4K10 A;  3QKC A;  5IK0 A;  3LGK A;  4F6V A;  4NFI F;  5IK6 A;  5JUZ F;  3OAC B;  1YYT A;  2E4O A;  4DXJ A;  1FPS A;  2F8Z F;  3NRI A;  4JYX A;  3KBK A;  2OA6 A;  1ZW5 A;  3RYE A;  4KPD A;  4RXC A;  5ERN A;  3PDE A;  2Z4W A;  3Q1O A;  4KQ5 A;  2E93 A;  3Q30 A;  2O1O A;  3TFN A;  2PS6 A;  3ICZ A;  2E8W A;  4JZB A;  1RQI A;  4EA2 A;  1VG7 A;  3QQV A;  2Z78 A;  3Q2Z A;  3KRC B;  5JA0 F;  3KRP B;  5EAT A;  2ZCQ A;  1YV5 A;  3N46 F;  1YYS A;  3N1W F;  3KRP A;  3VJC A;  5KSX F;  3SDV A;  3S9V A;  4NFK F;  5A0J A;  1N1B A;  2ZCS A;  4E9U A;  3MZV A;  5ILZ A;  5IKA A;  3TS7 A;  3M01 A;  2Q9Y A;  3ACY A;  3N5H F;  2E92 A;  2AZL A;  3VJ9 A;  3TFV A;  3WC9 A;  5EAS A;  3ZMB A;  5B0J A;  1UBX A;  2RAH A;  4KPJ A;  3KB9 A;  2E91 A;  5ERM A;  4H5E F;  4OMH A;  5ILY A;  3WCA A;  4NKE A;  4DZW A;  1YHM A;  5AFX A;  3ACW A;  1VG2 A;  3ICM A;  4RXA A;  3P8R A;  5EAU A;  1V4H A;  3LJI A;  3M00 A;  2F94 F;  4QXS F;  4LTZ A;  4XQR F;  5B02 A;  4RXD A;  2E8X A;  1V4J A;  3NF2 A;  5HN8 A;  1VG3 A;  3LLW A;  4LFE A;  3SDU A;  3ZOU A;  3VJE A;  3V1X A;  5IN8 A;  1RQJ A;  4HD1 A;  1WKZ A;  2ONG A;  4GP1 A;  2F89 F;  5HN7 A;  3ZL6 A;  2F92 F;  3IPI A;  5JV2 F;  3PH7 A;  4LZ0 A;  2AZK A;  3APZ A;  2H8O A;  3WJN A;  3WJO A;  3LOM A;  4FJQ A;  3DYH A;  4KWD A;  2AET A;  3AQC B;  3SAE A;  3TFP A;  4MC3 A;  3WCI A;  4JZX A;  3LG5 A;  1PS1 A;  5B01 A;  5IMI A;  4LA5 A;  1WL1 A;  2Z4Z A;  3N3L F;  3OAC A;  3NPR A;  2P1C A;  4ZQ8 A;  5B0K A;  5ILK A;  3KRF B;  5CG6 A;  4F62 A;  5A0I A;  2E90 A;  5IMN A;  3WEJ A;  3ICN A;  3WCG A;  5ILD A;  1V4K A;  4P0X A;  5IL8 A;  3WCD A;  1UBW A;  4LZ3 A;  4XQT F;  4RNQ A;  4Q23 A;  3N6K F;  3V1V A;  2J5C A;  4LFV F;  3G4D A;  2OPN A;  1RTR A;  3P8L A;  2AEL A;  3KRC A;  2PS8 A;  2FOR A;  4LTV A;  3CKE A;  4N9U A;  1YHL A;  5ILJ A;  4E1E A;  2Z50 A;  1HX9 A;  4JVJ F;  4OKZ A;  3M9U A;  4MC0 A;  3VJD A;  3CP6 A;  3EZ3 A;  2DH4 A;  4OKM A;  3ID0 A;  2E8U A;  1N21 A;  5ILI A;  3CC9 A;  1HXC A;  1WL0 A;  2F7M F;  3N1V F;  4MC8 A;  4N1Z F;  4KFA A;  3N3D A;  4NUA A;  1EZF A;  3AQB B;  4PVY F;  5E8H A;  3WEI A;  3ADZ A;  2PS7 A;  2ZY1 A;  2E94 A;  4NG6 A;  3V66 A;  2AZJ A;  5C05 A;  3SDQ A;  1N20 A;  5A0K A;  5B0M A;  3WCJ A;  3P5P A;  3LZ9 A;  3Q2Q A;  1V4E A;  3VJB A;  5DGS F;  5E8L A;  5AYP A;  1JFA A;  1WY0 A;  4QPF A;  1YQ7 A;  3NPK A;  4H5D F;  4L2X F;  5IKH A;  3VJA A;  1YJ4 A;  3KRA B;  3WCL A;  2J1O A;  4JXY A;  4GAX A;  3SDR A;  3DYG A;  5DGN F;  3ICK A;  3WCF A;  1WL3 A;  3KRA A;  1HXA A;  2I19 A;  4KKM A;  4DI5 A;  2Z7H A;  1YYQ A;  4KVI A;  3ASX A;  3OYR A;  3N49 F;  1HM4 A;  3N45 F;  3SDT A;  1N22 A;  4F6X A;  3P41 A;  1KIZ A;  4RXE A;  1VG6 A;  1VG4 A;  4LPG F;  4LLT A;  3WSB A;  5DIQ F;  5ERO A;  4EA0 A;  3LVS A;  5IMP A;  2ZEU A;  3N0F A;  5B0I A;  2PS4 A;  5DJV F;  3WCB A;  1N24 A;  4FP4 A;  3BNY A;  1UBY A;  5DJR F;  4EA1 A;  5HNA A;  4NKF A;  3WEH A;  3KRF A;  3LGZ B;  3LMD A;  3BNX A;  4LIX A;  2ONH A;  3S4J A;  3WSA A;  5DW7 A;  4PVX F;  3PYB A;  3WEK A;  1HM7 A;  4LOB A;  2AEK A;  4P0V A;  5IK9 A;  3VJ8 A;  2E8T A;  5DZ2 A;  3G4F A;  3WEG A;  3IBA A;  3WCE A;  2VF6 A;  3PKO A;  3KRO B;  3DYF A;  4P0W A;  4KQS A;  4KVY A;  4OMG A;  4KK2 A;  3EFQ A;  3LK5 A;  4DWG A;  3OAB B;  4JXN A;  5IVG A;  2ZCO A;  3KRO A;  4GP2 A;  2PS5 A;  5ILH A;  4XQS F;  4DHD A;  4GA3 A;  5I1U A;  2J1P A;  3OAB A;  5B03 A;  5IM1 A;  3LEE A;  3LSN A;  3WCH A;  1DGP A;  4UMJ A;  4LZC A;  2Q9Z A;  3RBM A;  2Z4Y A;  4KVW A;  2QIS A;  1N23 A;  5DHI A;  3N5J F;  5B0L A;  4KQU A;  3WEF A;  2F8C F;  2OPM A;  5CG5 A;  2EWG A;  1DI1 A;  2Z7I A;  5DGM F;  3WE9 A;  3WCC A;  3ZMC A;  4DWB A;  2Q80 A;  1N1Z A;  1V4I A;  3M02 A;  3RYW A;  1WL2 A;  4LFG A;  3RMG A;  3PYA A;  3ZCD A;  3ACX A;  4KVD A;  5IL3 A;  3MAV A;  1UBV A;  3WJK A;  5DJP F;  2ZCR A;  4LLS A;  4LPH F;  5H9D A;  4LXW A;  5AEL A;  4NFJ F;  3W7F A;  3UCA A;  2F9K F;  3B7L A;  1WMW A;  1YHK A;  2Z4V A;  3AE0 A;  5JV1 F;  1KIY A;  2FTZ A;  2E8V A;  2Z52 A;  4H5C F;  5ER8 A;  2Q58 A;  2OGD A;  3AQ0 A;  5HN9 A;  4RYP A;  1YYR A;  4LUU A;  4E9Z A;  5B00 A;  2ZEV A;  4DEM F;  1YYU A;  2Z4X A;  5E8K A;  4OGU A;  5DHK A;  2E95 A;  3LDW A;  4LA6 A;  3M0G A;  4KUX A; 
#chains in the Genus database with same CATH topology
 3WCM A;  3P5R A;  3TC1 A;  3EGT A;  5AHU B;  1JFG A;  5JV0 F;  4WK5 A;  1HXG A;  3N0G A;  4K10 A;  3QKC A;  5IK0 A;  3LGK A;  4F6V A;  4NFI F;  5IK6 A;  5JUZ F;  3OAC B;  1YYT A;  2E4O A;  4DXJ A;  1FPS A;  2F8Z F;  3NRI A;  4JYX A;  3KBK A;  2OA6 A;  1ZW5 A;  3RYE A;  4KPD A;  4RXC A;  5ERN A;  3PDE A;  2Z4W A;  3Q1O A;  4KQ5 A;  2E93 A;  3Q30 A;  2O1O A;  3TFN A;  2PS6 A;  3ICZ A;  2E8W A;  4JZB A;  1RQI A;  4EA2 A;  1VG7 A;  3QQV A;  2Z78 A;  3Q2Z A;  3KRC B;  5JA0 F;  3KRP B;  5EAT A;  2ZCQ A;  1YV5 A;  3N46 F;  1YYS A;  3N1W F;  3KRP A;  3VJC A;  5KSX F;  3SDV A;  3S9V A;  4NFK F;  5A0J A;  1N1B A;  2ZCS A;  4E9U A;  3MZV A;  5ILZ A;  5IKA A;  3TS7 A;  3M01 A;  2Q9Y A;  3ACY A;  3N5H F;  2E92 A;  2AZL A;  3VJ9 A;  3TFV A;  3WC9 A;  5EAS A;  3ZMB A;  5B0J A;  1UBX A;  2RAH A;  4KPJ A;  3KB9 A;  2E91 A;  5ERM A;  4H5E F;  4OMH A;  5ILY A;  3WCA A;  4NKE A;  4DZW A;  1YHM A;  5AFX A;  3ACW A;  1VG2 A;  3ICM A;  4RXA A;  3P8R A;  5EAU A;  1V4H A;  3LJI A;  3M00 A;  2F94 F;  4QXS F;  4LTZ A;  4XQR F;  5B02 A;  4RXD A;  2E8X A;  1V4J A;  3NF2 A;  5HN8 A;  1VG3 A;  3LLW A;  4LFE A;  3SDU A;  3ZOU A;  3VJE A;  3V1X A;  5IN8 A;  1RQJ A;  4HD1 A;  1WKZ A;  2ONG A;  4GP1 A;  2F89 F;  5HN7 A;  3ZL6 A;  2F92 F;  3IPI A;  5JV2 F;  3PH7 A;  4LZ0 A;  2AZK A;  3APZ A;  2H8O A;  3WJN A;  3WJO A;  3LOM A;  4FJQ A;  3DYH A;  4KWD A;  2AET A;  3AQC B;  3SAE A;  3TFP A;  4MC3 A;  3WCI A;  4JZX A;  3LG5 A;  1PS1 A;  5B01 A;  5IMI A;  4LA5 A;  1WL1 A;  2Z4Z A;  3N3L F;  3OAC A;  3NPR A;  2P1C A;  4ZQ8 A;  5B0K A;  5ILK A;  3KRF B;  5CG6 A;  4F62 A;  5A0I A;  2E90 A;  5IMN A;  3WEJ A;  3ICN A;  3WCG A;  5ILD A;  1V4K A;  4P0X A;  5IL8 A;  3WCD A;  1UBW A;  4LZ3 A;  4XQT F;  4RNQ A;  4Q23 A;  3N6K F;  3V1V A;  2J5C A;  4LFV F;  3G4D A;  2OPN A;  1RTR A;  3P8L A;  2AEL A;  3KRC A;  2PS8 A;  2FOR A;  4LTV A;  3CKE A;  4N9U A;  1YHL A;  5ILJ A;  4E1E A;  2Z50 A;  1HX9 A;  4JVJ F;  4OKZ A;  3M9U A;  4MC0 A;  3VJD A;  3CP6 A;  3EZ3 A;  2DH4 A;  4OKM A;  3ID0 A;  2E8U A;  1N21 A;  5ILI A;  3CC9 A;  1HXC A;  1WL0 A;  2F7M F;  3N1V F;  4MC8 A;  4N1Z F;  4KFA A;  3N3D A;  4NUA A;  1EZF A;  3AQB B;  4PVY F;  5E8H A;  3WEI A;  3ADZ A;  2PS7 A;  2ZY1 A;  2E94 A;  4NG6 A;  3V66 A;  2AZJ A;  5C05 A;  3SDQ A;  1N20 A;  5A0K A;  5B0M A;  3WCJ A;  3P5P A;  3LZ9 A;  3Q2Q A;  1V4E A;  3VJB A;  5DGS F;  5E8L A;  5AYP A;  1JFA A;  1WY0 A;  4QPF A;  1YQ7 A;  3NPK A;  4H5D F;  4L2X F;  5IKH A;  3VJA A;  1YJ4 A;  3KRA B;  3WCL A;  2J1O A;  4JXY A;  4GAX A;  3SDR A;  3DYG A;  5DGN F;  3ICK A;  3WCF A;  1WL3 A;  3KRA A;  1HXA A;  2I19 A;  4KKM A;  4DI5 A;  2Z7H A;  1YYQ A;  4KVI A;  3ASX A;  3OYR A;  3N49 F;  1HM4 A;  3N45 F;  3SDT A;  1N22 A;  4F6X A;  3P41 A;  1KIZ A;  4RXE A;  1VG6 A;  1VG4 A;  4LPG F;  4LLT A;  3WSB A;  5DIQ F;  5ERO A;  4EA0 A;  3LVS A;  5IMP A;  2ZEU A;  3N0F A;  5B0I A;  2PS4 A;  5DJV F;  3WCB A;  1N24 A;  4FP4 A;  3BNY A;  1UBY A;  5DJR F;  4EA1 A;  5HNA A;  4NKF A;  3WEH A;  3KRF A;  3LGZ B;  3LMD A;  3BNX A;  4LIX A;  2ONH A;  3S4J A;  3WSA A;  5DW7 A;  4PVX F;  3PYB A;  3WEK A;  1HM7 A;  4LOB A;  2AEK A;  4P0V A;  5IK9 A;  3VJ8 A;  2E8T A;  5DZ2 A;  3G4F A;  3WEG A;  3IBA A;  3WCE A;  2VF6 A;  3PKO A;  3KRO B;  3DYF A;  4P0W A;  4KQS A;  4KVY A;  4OMG A;  4KK2 A;  3EFQ A;  3LK5 A;  4DWG A;  3OAB B;  4JXN A;  5IVG A;  2ZCO A;  3KRO A;  4GP2 A;  2PS5 A;  5ILH A;  4XQS F;  4DHD A;  4GA3 A;  5I1U A;  2J1P A;  3OAB A;  5B03 A;  5IM1 A;  3LEE A;  3LSN A;  3WCH A;  1DGP A;  4UMJ A;  4LZC A;  2Q9Z A;  3RBM A;  2Z4Y A;  4KVW A;  2QIS A;  1N23 A;  5DHI A;  3N5J F;  5B0L A;  4KQU A;  3WEF A;  2F8C F;  2OPM A;  5CG5 A;  2EWG A;  1DI1 A;  2Z7I A;  5DGM F;  3WE9 A;  3WCC A;  3ZMC A;  4DWB A;  2Q80 A;  1N1Z A;  1V4I A;  3M02 A;  3RYW A;  1WL2 A;  4LFG A;  3RMG A;  3PYA A;  3ZCD A;  3ACX A;  4KVD A;  5IL3 A;  3MAV A;  1UBV A;  3WJK A;  5DJP F;  2ZCR A;  4LLS A;  4LPH F;  5H9D A;  4LXW A;  5AEL A;  4NFJ F;  3W7F A;  3UCA A;  2F9K F;  3B7L A;  1WMW A;  1YHK A;  2Z4V A;  3AE0 A;  5JV1 F;  1KIY A;  2FTZ A;  2E8V A;  2Z52 A;  4H5C F;  5ER8 A;  2Q58 A;  2OGD A;  3AQ0 A;  5HN9 A;  4RYP A;  1YYR A;  4LUU A;  4E9Z A;  5B00 A;  2ZEV A;  4DEM F;  1YYU A;  2Z4X A;  5E8K A;  4OGU A;  5DHK A;  2E95 A;  3LDW A;  4LA6 A;  3M0G A;  4KUX A; 
#chains in the Genus database with same CATH homology
 3WCM A;  3P5R A;  3TC1 A;  3EGT A;  5AHU B;  1JFG A;  5JV0 F;  4WK5 A;  1HXG A;  3N0G A;  4K10 A;  3QKC A;  5IK0 A;  3LGK A;  4F6V A;  4NFI F;  5IK6 A;  5JUZ F;  3OAC B;  1YYT A;  2E4O A;  4DXJ A;  1FPS A;  2F8Z F;  3NRI A;  4JYX A;  3KBK A;  2OA6 A;  1ZW5 A;  3RYE A;  4KPD A;  4RXC A;  5ERN A;  3PDE A;  2Z4W A;  3Q1O A;  4KQ5 A;  2E93 A;  3Q30 A;  2O1O A;  3TFN A;  2PS6 A;  3ICZ A;  2E8W A;  4JZB A;  1RQI A;  4EA2 A;  1VG7 A;  3QQV A;  2Z78 A;  3Q2Z A;  3KRC B;  5JA0 F;  3KRP B;  5EAT A;  2ZCQ A;  1YV5 A;  3N46 F;  1YYS A;  3N1W F;  3KRP A;  3VJC A;  5KSX F;  3SDV A;  3S9V A;  4NFK F;  5A0J A;  1N1B A;  2ZCS A;  4E9U A;  3MZV A;  5ILZ A;  5IKA A;  3TS7 A;  3M01 A;  2Q9Y A;  3ACY A;  3N5H F;  2E92 A;  2AZL A;  3VJ9 A;  3TFV A;  3WC9 A;  5EAS A;  3ZMB A;  5B0J A;  1UBX A;  2RAH A;  4KPJ A;  3KB9 A;  2E91 A;  5ERM A;  4H5E F;  4OMH A;  5ILY A;  3WCA A;  4NKE A;  4DZW A;  1YHM A;  5AFX A;  3ACW A;  1VG2 A;  3ICM A;  4RXA A;  3P8R A;  5EAU A;  1V4H A;  3LJI A;  3M00 A;  2F94 F;  4QXS F;  4LTZ A;  4XQR F;  5B02 A;  4RXD A;  2E8X A;  1V4J A;  3NF2 A;  5HN8 A;  1VG3 A;  3LLW A;  4LFE A;  3SDU A;  3ZOU A;  3VJE A;  3V1X A;  5IN8 A;  1RQJ A;  4HD1 A;  1WKZ A;  2ONG A;  4GP1 A;  2F89 F;  5HN7 A;  3ZL6 A;  2F92 F;  3IPI A;  5JV2 F;  3PH7 A;  4LZ0 A;  2AZK A;  3APZ A;  2H8O A;  3WJN A;  3WJO A;  3LOM A;  4FJQ A;  3DYH A;  4KWD A;  2AET A;  3AQC B;  3SAE A;  3TFP A;  4MC3 A;  3WCI A;  4JZX A;  3LG5 A;  1PS1 A;  5B01 A;  5IMI A;  4LA5 A;  1WL1 A;  2Z4Z A;  3N3L F;  3OAC A;  3NPR A;  2P1C A;  4ZQ8 A;  5B0K A;  5ILK A;  3KRF B;  5CG6 A;  4F62 A;  5A0I A;  2E90 A;  5IMN A;  3WEJ A;  3ICN A;  3WCG A;  5ILD A;  1V4K A;  4P0X A;  5IL8 A;  3WCD A;  1UBW A;  4LZ3 A;  4XQT F;  4RNQ A;  4Q23 A;  3N6K F;  3V1V A;  2J5C A;  4LFV F;  3G4D A;  2OPN A;  1RTR A;  3P8L A;  2AEL A;  3KRC A;  2PS8 A;  2FOR A;  4LTV A;  3CKE A;  4N9U A;  1YHL A;  5ILJ A;  4E1E A;  2Z50 A;  1HX9 A;  4JVJ F;  4OKZ A;  3M9U A;  4MC0 A;  3VJD A;  3CP6 A;  3EZ3 A;  2DH4 A;  4OKM A;  3ID0 A;  2E8U A;  1N21 A;  5ILI A;  3CC9 A;  1HXC A;  1WL0 A;  2F7M F;  3N1V F;  4MC8 A;  4N1Z F;  4KFA A;  3N3D A;  4NUA A;  1EZF A;  3AQB B;  4PVY F;  5E8H A;  3WEI A;  3ADZ A;  2PS7 A;  2ZY1 A;  2E94 A;  4NG6 A;  3V66 A;  2AZJ A;  5C05 A;  3SDQ A;  1N20 A;  5A0K A;  5B0M A;  3WCJ A;  3P5P A;  3LZ9 A;  3Q2Q A;  1V4E A;  3VJB A;  5DGS F;  5E8L A;  5AYP A;  1JFA A;  1WY0 A;  4QPF A;  1YQ7 A;  3NPK A;  4H5D F;  4L2X F;  5IKH A;  3VJA A;  1YJ4 A;  3KRA B;  3WCL A;  2J1O A;  4JXY A;  4GAX A;  3SDR A;  3DYG A;  5DGN F;  3ICK A;  3WCF A;  1WL3 A;  3KRA A;  1HXA A;  2I19 A;  4KKM A;  4DI5 A;  2Z7H A;  1YYQ A;  4KVI A;  3ASX A;  3OYR A;  3N49 F;  1HM4 A;  3N45 F;  3SDT A;  1N22 A;  4F6X A;  3P41 A;  1KIZ A;  4RXE A;  1VG6 A;  1VG4 A;  4LPG F;  4LLT A;  3WSB A;  5DIQ F;  5ERO A;  4EA0 A;  3LVS A;  5IMP A;  2ZEU A;  3N0F A;  5B0I A;  2PS4 A;  5DJV F;  3WCB A;  1N24 A;  4FP4 A;  3BNY A;  1UBY A;  5DJR F;  4EA1 A;  5HNA A;  4NKF A;  3WEH A;  3KRF A;  3LGZ B;  3LMD A;  3BNX A;  4LIX A;  2ONH A;  3S4J A;  3WSA A;  5DW7 A;  4PVX F;  3PYB A;  3WEK A;  1HM7 A;  4LOB A;  2AEK A;  4P0V A;  5IK9 A;  3VJ8 A;  2E8T A;  5DZ2 A;  3G4F A;  3WEG A;  3IBA A;  3WCE A;  2VF6 A;  3PKO A;  3KRO B;  3DYF A;  4P0W A;  4KQS A;  4KVY A;  4OMG A;  4KK2 A;  3EFQ A;  3LK5 A;  4DWG A;  3OAB B;  4JXN A;  5IVG A;  2ZCO A;  3KRO A;  4GP2 A;  2PS5 A;  5ILH A;  4XQS F;  4DHD A;  4GA3 A;  5I1U A;  2J1P A;  3OAB A;  5B03 A;  5IM1 A;  3LEE A;  3LSN A;  3WCH A;  1DGP A;  4UMJ A;  4LZC A;  2Q9Z A;  3RBM A;  2Z4Y A;  4KVW A;  2QIS A;  1N23 A;  5DHI A;  3N5J F;  5B0L A;  4KQU A;  3WEF A;  2F8C F;  2OPM A;  5CG5 A;  2EWG A;  1DI1 A;  2Z7I A;  5DGM F;  3WE9 A;  3WCC A;  3ZMC A;  4DWB A;  2Q80 A;  1N1Z A;  1V4I A;  3M02 A;  3RYW A;  1WL2 A;  4LFG A;  3RMG A;  3PYA A;  3ZCD A;  3ACX A;  4KVD A;  5IL3 A;  3MAV A;  1UBV A;  3WJK A;  5DJP F;  2ZCR A;  4LLS A;  4LPH F;  5H9D A;  4LXW A;  5AEL A;  4NFJ F;  3W7F A;  3UCA A;  2F9K F;  3B7L A;  1WMW A;  1YHK A;  2Z4V A;  3AE0 A;  5JV1 F;  1KIY A;  2FTZ A;  2E8V A;  2Z52 A;  4H5C F;  5ER8 A;  2Q58 A;  2OGD A;  3AQ0 A;  5HN9 A;  4RYP A;  1YYR A;  4LUU A;  4E9Z A;  5B00 A;  2ZEV A;  4DEM F;  1YYU A;  2Z4X A;  5E8K A;  4OGU A;  5DHK A;  2E95 A;  3LDW A;  4LA6 A;  3M0G A;  4KUX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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