3CPWE

The structure of the antibiotic linezolid bound to the large ribosomal subunit of haloarcula marismortui
Total Genus 37
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
172
structure length
172
Chain Sequence
PRVELEIPEDVDAEQDHLDITVEGDNGSVTRRLWYPDIDVSVDGDTVVIESDEDNAKTMSTIGTFQSHIENMFHGVTEGWEYGMEVFYSHFPMQVNVEGDEVVIENFLGEKAPRRTTIHGDTDVEIDGEELTVSGPDIEAVGQTAADIEQLTRINDKDVRVFQDGVYITRKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of the Oxazolidinone Antibiotic Linezolid Bound to the 50S Ribosomal Subunit
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S RIBOSOMAL RNA
total genus 37
structure length 172
sequence length 172
ec nomenclature
pdb deposition date 2008-04-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00347 Ribosomal_L6 Ribosomal protein L6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3cpwE02
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3cpwE01
3CCRE 3CXCE 1S72E 2CQLA 5JVGE 5AN9B 5MLCH 3CCUE 1Q81G 1YHQE 1VQ8E 1VQKE 5HL7E 1VQ4E 1VQ5E 4IO9E 3DLLE 3CPWE 3CCLE 3PIPE 1VQPE 3CD6E 1Q82G 4WF9E 5JVHE 3I56E 4WCEE 3CC2E 5DM7E 3I55E 5GAEG 1VQME 5DM6E 1YJWE 1YJ9E 1VQNE 4IOAE 3CC7E 5H1SI 1Q7YG 1K8AG 3J7ZG 4WFBE 3CC4E 4IOCE 2ZJPE 1YIJE 2QA4E 1NJIG 3CMAE 2ZJRE 1VQLE 1KC8G 3CCQE 4WFNE 3CCSE 1YI2E 3OW2E 1VQ9E 2ZJQE 1YITE 2QEXE 4U67E 1RL6A 1YJNE 4WFAE 5GADG 3CCVE 3G71E 1JJ2E 3CCJE 3PIOE 1N8RG 1K9MG 1Q86G 1QVGE 2OTLE 1VQ6E 3CMEE 4UY8G 1W2BE 3CCME 1KQSE 1VQOE 3G4SE 1K73G 1M1KG 5GAGG 3CF5E 1KD1G 1M90G 3G6EE 1QVFE 5GAHG 1VQ7E 2OTJE 3CCEE
chains in the Genus database with same CATH superfamily
3CCRE 3CXCE 3IG9A 1S72E 2CQLA 5JVGE 5AN9B 3CKGA 5MLCH 3CCUE 1Q81G 1OSPO 1YHQE 1VQ8E 1VQKE 5HL7E 1RJLC 2OYBO 2OY8A 1VQ4E 1VQ5E 4IO9E 3DLLE 3CPWE 3CCLE 3PIPE 2OY7A 1VQPE 3CD6E 2OL8O 1Q82G 4WF9E 5JVHE 2OY5O 3AUMO 3I56E 4WCEE 3CC2E 5B10O 5DM7E 5GAEG 3I55E 1VQME 2G8CO 5DM6E 1YJWE 1YJ9E 2AF5A 5B2AO 3IGEA 1VQNE 5B11O 4IOAE 3CC7E 5H1SI 1Q7YG 1K8AG 3J7ZG 4WFBE 3CC4E 4IOCE 2I5ZO 2HKDA 2ZJPE 1YIJE 2QA4E 1NJIG 3CMAE 2FKJA 2ZJRE 1VQLE 3CKFA 1KC8G 3CCQE 4WFNE 1FJ1E 3CCSE 1YI2E 3OW2E 2I5VO 1VQ9E 2ZJQE 1YITE 2QEXE 3EC5A 4U67E 1RL6A 1YJNE 4WFAE 5GADG 3CCVE 3G71E 1JJ2E 3CCJE 3PIOE 1N8RG 1K9MG 1Q86G 1QVGE 2OTLE 1VQ6E 3CMEE 2OL7A 2OL6O 5B3MO 1P4PA 4UY8G 1W2BE 2PI3O 3CCME 1KQSE 2FKGA 1VQOE 3G4SE 1K73G 1M1KG 5GAGG 3CF5E 1KD1G 1M90G 3G6EE 1QVFE 5GAHG 1VQ7E 2OY1O 2OTJE 3CCEE
chains in the Genus database with same CATH topology
3CCRE 3CXCE 1S72E 2CQLA 5JVGE 5AN9B 5MLCH 3CCUE 1Q81G 1YHQE 1VQ8E 1VQKE 5HL7E 1VQ4E 1VQ5E 4IO9E 3DLLE 3CPWE 3CCLE 3PIPE 1VQPE 3CD6E 1Q82G 4WF9E 5JVHE 3I56E 4WCEE 3CC2E 5DM7E 3I55E 5GAEG 1VQME 5DM6E 1YJWE 1YJ9E 1VQNE 4IOAE 3CC7E 5H1SI 1Q7YG 1K8AG 3J7ZG 4WFBE 3CC4E 4IOCE 2ZJPE 1YIJE 2QA4E 1NJIG 3CMAE 2ZJRE 1VQLE 1KC8G 3CCQE 4WFNE 3CCSE 1YI2E 3OW2E 1VQ9E 2ZJQE 1YITE 2QEXE 4U67E 1RL6A 1YJNE 4WFAE 5GADG 3CCVE 3G71E 1JJ2E 3CCJE 3PIOE 1N8RG 1K9MG 1Q86G 1QVGE 2OTLE 1VQ6E 3CMEE 4UY8G 1W2BE 3CCME 1KQSE 1VQOE 3G4SE 1K73G 1M1KG 5GAGG 3CF5E 1KD1G 1M90G 3G6EE 1QVFE 5GAHG 1VQ7E 2OTJE 3CCEE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CCR E;  3CXC E;  1S72 E;  2CQL A;  5JVG E;  5AN9 B;  5MLC H;  3CCU E;  1Q81 G;  1YHQ E;  1VQ8 E;  1VQK E;  5HL7 E;  1VQ4 E;  1VQ5 E;  4IO9 E;  3DLL E;  3CPW E;  3CCL E;  3PIP E;  1VQP E;  3CD6 E;  1Q82 G;  4WF9 E;  5JVH E;  3I56 E;  4WCE E;  3CC2 E;  5DM7 E;  3I55 E;  5GAE G;  1VQM E;  5DM6 E;  1YJW E;  1YJ9 E;  1VQN E;  4IOA E;  3CC7 E;  5H1S I;  1Q7Y G;  1K8A G;  3J7Z G;  4WFB E;  3CC4 E;  4IOC E;  2ZJP E;  1YIJ E;  2QA4 E;  1NJI G;  3CMA E;  2ZJR E;  1VQL E;  1KC8 G;  3CCQ E;  4WFN E;  3CCS E;  1YI2 E;  3OW2 E;  1VQ9 E;  2ZJQ E;  1YIT E;  2QEX E;  4U67 E;  1RL6 A;  1YJN E;  4WFA E;  5GAD G;  3CCV E;  3G71 E;  1JJ2 E;  3CCJ E;  3PIO E;  1N8R G;  1K9M G;  1Q86 G;  1QVG E;  2OTL E;  1VQ6 E;  3CME E;  4UY8 G;  1W2B E;  3CCM E;  1KQS E;  1VQO E;  3G4S E;  1K73 G;  1M1K G;  5GAG G;  3CF5 E;  1KD1 G;  1M90 G;  3G6E E;  1QVF E;  5GAH G;  1VQ7 E;  2OTJ E;  3CCE E; 
#chains in the Genus database with same CATH topology
 3CCR E;  3CXC E;  3IG9 A;  1S72 E;  2CQL A;  5JVG E;  5AN9 B;  3CKG A;  5MLC H;  3CCU E;  1Q81 G;  1OSP O;  1YHQ E;  1VQ8 E;  1VQK E;  5HL7 E;  1RJL C;  2OYB O;  2OY8 A;  1VQ4 E;  1VQ5 E;  4IO9 E;  3DLL E;  3CPW E;  3CCL E;  3PIP E;  2OY7 A;  1VQP E;  3CD6 E;  2OL8 O;  1Q82 G;  4WF9 E;  5JVH E;  2OY5 O;  3AUM O;  3I56 E;  4WCE E;  3CC2 E;  5B10 O;  5DM7 E;  5GAE G;  3I55 E;  1VQM E;  2G8C O;  5DM6 E;  1YJW E;  1YJ9 E;  2AF5 A;  5B2A O;  3IGE A;  1VQN E;  5B11 O;  4IOA E;  3CC7 E;  5H1S I;  1Q7Y G;  1K8A G;  3J7Z G;  4WFB E;  3CC4 E;  4IOC E;  2I5Z O;  2HKD A;  2ZJP E;  1YIJ E;  2QA4 E;  1NJI G;  3CMA E;  2FKJ A;  2ZJR E;  1VQL E;  3CKF A;  1KC8 G;  3CCQ E;  4WFN E;  1FJ1 E;  3CCS E;  1YI2 E;  3OW2 E;  2I5V O;  1VQ9 E;  2ZJQ E;  1YIT E;  2QEX E;  3EC5 A;  4U67 E;  1RL6 A;  1YJN E;  4WFA E;  5GAD G;  3CCV E;  3G71 E;  1JJ2 E;  3CCJ E;  3PIO E;  1N8R G;  1K9M G;  1Q86 G;  1QVG E;  2OTL E;  1VQ6 E;  3CME E;  2OL7 A;  2OL6 O;  5B3M O;  1P4P A;  4UY8 G;  1W2B E;  2PI3 O;  3CCM E;  1KQS E;  2FKG A;  1VQO E;  3G4S E;  1K73 G;  1M1K G;  5GAG G;  3CF5 E;  1KD1 G;  1M90 G;  3G6E E;  1QVF E;  5GAH G;  1VQ7 E;  2OY1 O;  2OTJ E;  3CCE E; 
#chains in the Genus database with same CATH homology
 3CCR E;  3CXC E;  1S72 E;  2CQL A;  5JVG E;  5AN9 B;  5MLC H;  3CCU E;  1Q81 G;  1YHQ E;  1VQ8 E;  1VQK E;  5HL7 E;  1VQ4 E;  1VQ5 E;  4IO9 E;  3DLL E;  3CPW E;  3CCL E;  3PIP E;  1VQP E;  3CD6 E;  1Q82 G;  4WF9 E;  5JVH E;  3I56 E;  4WCE E;  3CC2 E;  5DM7 E;  3I55 E;  5GAE G;  1VQM E;  5DM6 E;  1YJW E;  1YJ9 E;  1VQN E;  4IOA E;  3CC7 E;  5H1S I;  1Q7Y G;  1K8A G;  3J7Z G;  4WFB E;  3CC4 E;  4IOC E;  2ZJP E;  1YIJ E;  2QA4 E;  1NJI G;  3CMA E;  2ZJR E;  1VQL E;  1KC8 G;  3CCQ E;  4WFN E;  3CCS E;  1YI2 E;  3OW2 E;  1VQ9 E;  2ZJQ E;  1YIT E;  2QEX E;  4U67 E;  1RL6 A;  1YJN E;  4WFA E;  5GAD G;  3CCV E;  3G71 E;  1JJ2 E;  3CCJ E;  3PIO E;  1N8R G;  1K9M G;  1Q86 G;  1QVG E;  2OTL E;  1VQ6 E;  3CME E;  4UY8 G;  1W2B E;  3CCM E;  1KQS E;  1VQO E;  3G4S E;  1K73 G;  1M1K G;  5GAG G;  3CF5 E;  1KD1 G;  1M90 G;  3G6E E;  1QVF E;  5GAH G;  1VQ7 E;  2OTJ E;  3CCE E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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