3CQZC

Crystal structure of 10 subunit rna polymerase ii in complex with the inhibitor alpha-amanitin
Total Genus 58
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
58
sequence length
265
structure length
265
Chain Sequence
EEGPQVKIREASKDNVDFILSNVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLADEFIAHRLGLIPLQSMDIEQLEYSRDCFCEDHCDKCSVVLTLQAFGESESTTNVYSKDLVIVSNLMGRNIGHPIIQDKEGNGVLICKLRKGQELKLTCVAKKGIAKEHAKWGPAAAIEFEYDPWNKLKHTDYWYEQDSAKEWPQSKNCEYEDPPNEGDPFDYKAQADTFYMNVESVGSIPVDQVVVRGIDTLQKKVASILLALTQMDQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1
publication title The RNA Polymerase II Trigger Loop Functions in Substrate Selection and is Directly Targeted by Alpha-Amanitin.
pubmed doi rcsb
molecule tags Transcription/toxin
total genus 58
structure length 265
sequence length 265
ec nomenclature
pdb deposition date 2008-04-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF01000 RNA_pol_A_bac RNA polymerase Rpb3/RpoA insert domain
C PF01193 RNA_pol_L RNA polymerase Rpb3/Rpb11 dimerisation domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.120.12 Mainly Beta Beta Complex RNA Polymerase Alpha Subunit; Chain A, domain 2 DNA-directed RNA polymerase, insert domain 3cqzC02
3.30.1360.10 Alpha Beta 2-Layer Sandwich Gyrase A; domain 2 RNA polymerase, RBP11-like subunit 3cqzC01
3PO3C 4XLPA 2E2IC 1Y1VK 2PMZD 4QJVB 1IW7A 4A3BC 4MEYA 1YNNA 3RZOC 1R9TC 3M4OC 4A3FK 4A3LC 1K83C 3GTKK 4Q4ZA 3GTPK 2WAQL 4A3GC 4BY1K 5TMCA 2YU9K 4QIWD 2JA6C 4C3IC 2R92C 2NVTK 3HOYK 2CW0A 4C3JC 3PO2C 5M3FK 5IP9K 2JA5C 4LK0A 2PPBA 3S16C 2PA8L 3H0GK 2WB1D 5IYDK 4A3CK 4A3JK 1TWCC 3I4MC 2R7ZC 2O5JA 5D4DA 2NVQK 4YFNA 3GTLK 5FLMC 4XSXA 1HQMA 3S17C 4X6AC 3HOWC 2B63K 5C4JK 3HOVK 4A3IC 4C2MC 4AYBD 4G7HA 4A3MK 4BBRK 5M5XK 3S2DK 3CQZC 4MEXA 4A93K 1TWHK 4OINA 2O5IA 4BXXC 5M3MK 4BY7K 1TWFC 4A3EC 3GTOK 3HOZK 4KN7A 1TWGK 4A3DC 3H3VL 4A3KC 2E2HK 2WAQD 3S2HC 5FJ8K 4C3HK 4Q5SA 4Y7NK 1SFOK 3GTQK 1I6HK 4LJZA 3HOXK 3RZDK 4KN4A 3S1QC 3HOUK 4OIOA 3I4NC 2E2JC 5C3EC 4G7OA 2PA8D 1XPPA 4OIQA 1Y1VC 1TWAC 2A68A 5IYCC 2NVXK 3M3YK 3S1MK 4Y52K 4NOIA 3S15K 3GTGK 2A69A 2Y0SL 4A3FC 2JA8K 2E2IK 5C44K 4BBSK 3S1RK 1Y1WK 2BE5A 4BY1C 2YU9C 2NVYC 3HOYC 4A3LK 2NVTC 3S14K 5IP9C 4GZYA 2R93C 1WCMK 3H3VD 2JA6K 1I3QK 5IYDC 5IYBK 3HKZL 3GTMK 3S16K 3FKIK 3GTLC 1I6VA 3EQLA 3GTJC 2B63C 4XLNA 4OIRA 1I50K 3K7AK 2JA7K 5M5YK 4BBRC 5TMFA 2VUMC 4A93C 1TWHC 5C4XK 3HOWK 1ZYRA 3S1NC 3GTOC 1TWGC 5IP7K 2A6EA 2E2HC 4C3HC 3WODA 3GTQC 1I6HC 4A3EK 3PO3K 3HOXC 5M5WK 3GTKC 4YG2A 4YFKA 4OIPA 3GTPC 3RZOK 3M4OK 1R9TK 4A3BK 1K83K 3I4NK 3HKZD 2NVXC 4A3GK 3GTGC 4C3IK 2R92K 2JA8C 4AYBL 1TWAK 5IYCK 3H0GC 4C3JK 5C44C 4BBSC 3S1RC 4A3JC 1Y1WC 4A3CC 3PO2K 2JA5K 1BDFA 4LLGA 2NVQC 3S14C 1TWCK 3HOVC 3S15C 2PMZL 3I4MK 4XSZA 1WCMC 5C4JC 2NVYK 2R7ZK 4KMUA 1I3QC 4ZH4A 4A3MC 3S2DC 5FLMK 5IYBC 4X6AK 4QJVA 3S17K 4MQ9A 2R93K 2Y0SD 4BY7C 4C2MK 4A3IK 3GTMC 3HOZC 4LK1A 3FKIC 4QIWL 3CQZK 4YFXA 4BXXK 4Y7NC 1SFOC 1I50C 4JK1A 3K7AC 1TWFK 2JA7C 2A6HA 3RZDC 1YNJA 4A3KK 3HOUC 3S2HK 4A3DK 4G7ZA 3GTJK 5C4XC 2WB1L 3DXJA 3S1QK 5IP7C 2VUMK 1SMYA 3M3YC 3S1MC 5C3EK 4Y52C 2E2JK 3S1NK
chains in the Genus database with same CATH superfamily
4WJ3M 2E2IC 1Y1VK 2KQ1A 3A8IA 3AQOA 5L46A 1IW7A 3M4OC 1R9TC 4A3FK 2CFAB 1JOEA 1K83C 4KC6A 3BP3A 3V4GA 2WAQL 2YU9K 2R92C 5M3FK 3A8JA 3S16C 5JVHS 2WB1D 4A3JK 1TWCC 2JA5A 4WJ4A 5D4DA 2NVQK 3AD8C 5FLMC 3L4KA 3HOVK 4X6AC 4WILA 3HOWC 4IO9S 4AYBD 2ZJRS 4G7HA 2NVYA 4A3MK 4KATA 4MEXA 1TWHK 2O5IA 3TFIA 4BY7K 3GTOK 1ZVUA 3H3VL 2E2HK 3CQZA 4Q5SA 4Y7NK 3ERED 1J6WA 4M1XA 3I4NC 3GTJA 4G7OA 1DCPA 1X31C 3OPFA 4GTFA 3TTGA 1Y1VC 2A68A 3VA7A 1F9NA 3GTGK 2V6UA 4A3FC 4P5AA 1F7UA 4BBSK 1XZPB 3S1RK 1V5VA 2YU9C 2W7VA 4A3LK 1IBAA 3S14K 1IE0A 4PAAA 3GTPA 1J6VA 5IYBK 3BUEA 5HL7S 3HKZL 4O2DA 3GTMK 2ZUEA 4WCES 4LQYA 1TWHC 4WFBS 3GTOC 5IP7K 2E2HC 1EQRA 2RH6A 3WODA 5TJ3A 4A3EK 1TWGA 5JFEA 5M5WK 3GTKC 4FZBA 4YG2A 4YFKA 4G0VA 3RZOK 1XXCA 4DDQA 4A3GK 3GTGC 4GTDA 3DLLS 3SZYA 3H0GC 1PJ7A 4KB2A 4BBSC 3S1RC 4LR2A 4C45A 2GAHC 1HI9A 2JA5K 4LLGA 1BS2A 2FQTA 3S14C 4RMFA 1B4AA 2NVYK 2FQOA 5IYBC 4MQ9A 3JSTA 3GTMC 2JA6A 3IPJA 2CFAA 3CQZK 4XCHA 1WIHA 1EH1A 2KXYA 1BJTA 1J6XA 3RZDC 4A3KK 3GTJK 4GT9A 1O2FB 5IP7C 4KB4A 3S1NK 1WOOA 5CJ9A 3A8KA 1DD5A 2PMZD 3CF5S 4MEYA 1YNNA 3RZOC 3PIPS 2ZJQS 3GTPK 4A3GC 4QIWD 3HOYK 2NVTK 2CW0A 2JA5C 2PA8L 1TWAA 5IYDK 4A3CK 3S15K 2B63K 5E68A 4WFAS 4BBRK 3S2DK 3CQZC 1XZPA 5M3MK 2R93A 1TWGK 4A3KC 3GEEA 2WAQD 4G0UA 5FJ8K 4LJZA 4U67S 3HOUK 1G51A 4OIOA 5IORA 1ZXOA 4OIQA 3M3YK 3S1MK 4Y52K 3N0CA 2A69A 2EBBA 2Y0SL 3FHZA 2BE5A 3HOYC 2NVTC 4P5BA 1AB4A 3H3VD 2JA6K 4KASA 2XCQA 3LPXA 5IYDC 1VRQC 1F93A 2P8TA 1IL2A 2B63C 4XLNA 4OIRA 3N0BA 1VGXA 4BBRC 2VUMC 4GTLA 3GSIA 1TWGC 2GAGC 1IS1A 3PO3K 1XZQA 1SFOA 4A3BK 3GIRA 3GTQA 4GTEA 3HKZD 4KM9A 1XXBA 4AYBL 1TWAK 5IYCK 2NVXA 4A3JC 1B4BA 2NVQC 2E2IA 5CHPA 4KMHA 3HOVC 1O27A 4FM9A 1O29A 4A3MC 3G4AA 2R93K 4A3IK 4BY7C 1WCMA 3SZZA 4C2MK 1PJ6A 1F7VA 4YFXA 4Y7NC 4IOCS 4A3DK 1YNJA 3FKIA 3S2HK 1TWCA 1UV7A 1WOPA 1I50A 2JA7A 1WQFA 2E2JK 5C3EK 3PO3C 1JVIA 4AH6A 4A3BC 1O25A 3AD9C 4LOWA 4GFQA 4A3LC 1O26A 4GTBA 2JH3A 1VJEA 3N3YA 5TMCA 1XZQB 2PPBA 1PJ5A 4BLBA 2O5JA 3G4CA 4XSXA 1HQMA 4GTCA 4PABA 5C4JK 4A3IC 4C2MC 1WSVA 3FOFA 2R7ZA 5M5XK 2XCRB 4OINA 4A3EC 3HOZK 4KN7A 4A3DC 3AD7C 3S2HC 2GSNA 4C3HK 1SFOK 1EFWA 3GTQK 1I6HK 2KPUA 1L0WA 1TWFA 3FOEA 4KN4A 1VH2A 2XCOA 3AQPA 2E2JC 5C3EC 2PA8D 2NVXK 3T01A 1GE9A 5JVGS 4NOIA 1USOA 3CAGA 2E2IK 5C44K 2NVYC 3GTKA 3MMLB 4KARA 1WCMK 3QX3A 3S16K 3FKIK 3H0GA 3NUHA 3GTJC 1O28A 1I50K 3K7AK 2JA7K 4KMDA 5TMFA 3GTLA 3HOWK 1ZYRA 2L5NA 3S1NC 3S0XA 1O2AA 4WF9S 3OEPA 2A6EA 1J98A 1RU0A 4C3HC 3GTQC 1I6HC 2KWAA 3GTPC 3L4JA 3I4NK 2NVXC 5EGHA 2GSUA 4GTAA 4C3IK 2V6SA 4C3JK 3PO2K 5C44C 1WQGA 4A3CC 3GEIA 4P9SA 3T00A 3I4MK 3S15C 1Y1WA 1WCMC 2R7ZK 2ZFZA 3TFJA 3S2DC 3S17K 1WOSA 4LK1A 1I3QA 3FKIC 1FEUA 1DCOA 5IOTA 4BXXK 1WQHA 1I50C 1TWFK 3K7AC 3LAPA 2JA7C 2Y3PA 2A6HA 5HL8A 3HOUC 1ISEA 4G7ZA 2WB1L 3S1QK 4G0WA 1SMYA 3M3YC 3S1MC 4Y52C 4XLPA 4QJVB 4J3NA 3HXAA 3GTKK 4Q4ZA 4BY1K 1ZQ1C 2D6FC 2JA6C 2PHCB 4C3IC 1R9TA 4KMAA 1K83A 4C3JC 3PO2C 3GEHA 5IP9K 4LK0A 2R92A 3H0GK 3I4MC 2ZUFA 2R7ZC 1VLOA 4YFNA 3GTLK 3S17C 1YCLA 4A93K 1IQ0A 4BXXC 1JQWA 1INNA 1TWFC 2L3UA 3TFHA 3HOXK 3RZDK 3S1QC 3T02A 2B63A 3OREA 1XPPA 1TWAC 5IYCC 2VUMA 1DCHA 1USMA 3GDZA 2JA8K 4WFNS 1XXAA 4KAWX 1Y1VA 1Y1WK 3LYWA 4BY1C 5IOSA 1BGWA 5DM7S 5HQHA 5EGEA 5IP9C 1EI6A 4GZYA 2R93C 2YU9A 3PIOS 1I3QK 2GSOA 3LAJA 3GTLC 1I6VA 3EQLA 5DM6S 3ADAC 5M5YK 1YX2A 1ZBSA 4A93C 5C4XK 4BKWA 1WSRA 1O2BA 2ZJPS 3AH5A 1TWHA 3GTOA 3HOXC 2E2HA 4OIPA 1O24A 3M4OK 1R9TK 4BLAA 1WORA 1K83K 3Q3QA 2R92K 2JA8C 5JVOA 1Y1WC 1EK8A 4KDDA 1BDFA 3GTGA 2RGRA 1TWCK 2PMZL 4IOAS 4XSZA 5C4JC 4KMUA 3BP8C 1I3QC 4ZH4A 5IOQA 1KQ4A 5FLMK 4X6AK 4QJVA 1C0AA 2Y0SD 2P5MA 2V6TA 3HOZC 4QIWL 4ILDA 1SFOC 4JK1A 3GTMA 5C4XC 4KM8A 3DXJA 2VUMK
chains in the Genus database with same CATH topology
3PO3C 4XLPA 2E2IC 1Y1VK 2PMZD 4QJVB 1IW7A 4A3BC 4MEYA 1YNNA 3RZOC 1R9TC 3M4OC 4A3FK 4A3LC 1K83C 3GTKK 4Q4ZA 3GTPK 2WAQL 4A3GC 4BY1K 5TMCA 2YU9K 4QIWD 2JA6C 4C3IC 2R92C 2NVTK 3HOYK 2CW0A 4C3JC 3PO2C 5M3FK 5IP9K 2JA5C 4LK0A 2PPBA 3S16C 2PA8L 3H0GK 2WB1D 5IYDK 4A3CK 4A3JK 1TWCC 3I4MC 2R7ZC 2O5JA 5D4DA 2NVQK 4YFNA 3GTLK 5FLMC 4XSXA 1HQMA 3S17C 4X6AC 3HOWC 2B63K 5C4JK 3HOVK 4A3IC 4C2MC 4AYBD 4G7HA 4A3MK 4BBRK 5M5XK 3S2DK 3CQZC 4MEXA 4A93K 1TWHK 4OINA 2O5IA 4BXXC 5M3MK 4BY7K 1TWFC 4A3EC 3GTOK 3HOZK 4KN7A 1TWGK 4A3DC 3H3VL 4A3KC 2E2HK 2WAQD 3S2HC 5FJ8K 4C3HK 4Q5SA 4Y7NK 1SFOK 3GTQK 1I6HK 4LJZA 3HOXK 3RZDK 4KN4A 3S1QC 3HOUK 4OIOA 3I4NC 2E2JC 5C3EC 4G7OA 2PA8D 1XPPA 4OIQA 1Y1VC 1TWAC 2A68A 5IYCC 2NVXK 3M3YK 3S1MK 4Y52K 4NOIA 3S15K 3GTGK 2A69A 2Y0SL 4A3FC 2JA8K 2E2IK 5C44K 4BBSK 3S1RK 1Y1WK 2BE5A 4BY1C 2YU9C 2NVYC 3HOYC 4A3LK 2NVTC 3S14K 5IP9C 4GZYA 2R93C 1WCMK 3H3VD 2JA6K 1I3QK 5IYDC 5IYBK 3HKZL 3GTMK 3S16K 3FKIK 3GTLC 1I6VA 3EQLA 3GTJC 2B63C 4XLNA 4OIRA 1I50K 3K7AK 2JA7K 5M5YK 4BBRC 5TMFA 2VUMC 4A93C 1TWHC 5C4XK 3HOWK 1ZYRA 3S1NC 3GTOC 1TWGC 5IP7K 2A6EA 2E2HC 4C3HC 3WODA 3GTQC 1I6HC 4A3EK 3PO3K 3HOXC 5M5WK 3GTKC 4YG2A 4YFKA 4OIPA 3GTPC 3RZOK 3M4OK 1R9TK 4A3BK 1K83K 3I4NK 3HKZD 2NVXC 4A3GK 3GTGC 4C3IK 2R92K 2JA8C 4AYBL 1TWAK 5IYCK 3H0GC 4C3JK 5C44C 4BBSC 3S1RC 4A3JC 1Y1WC 4A3CC 3PO2K 2JA5K 1BDFA 4LLGA 2NVQC 3S14C 1TWCK 3HOVC 3S15C 2PMZL 3I4MK 4XSZA 1WCMC 5C4JC 2NVYK 2R7ZK 4KMUA 1I3QC 4ZH4A 4A3MC 3S2DC 5FLMK 5IYBC 4X6AK 4QJVA 3S17K 4MQ9A 2R93K 2Y0SD 4BY7C 4C2MK 4A3IK 3GTMC 3HOZC 4LK1A 3FKIC 4QIWL 3CQZK 4YFXA 4BXXK 4Y7NC 1SFOC 1I50C 4JK1A 3K7AC 1TWFK 2JA7C 2A6HA 3RZDC 1YNJA 4A3KK 3HOUC 3S2HK 4A3DK 4G7ZA 3GTJK 5C4XC 2WB1L 3DXJA 3S1QK 5IP7C 2VUMK 1SMYA 3M3YC 3S1MC 5C3EK 4Y52C 2E2JK 3S1NK
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3PO3 C;  4XLP A;  2E2I C;  1Y1V K;  2PMZ D;  4QJV B;  1IW7 A;  4A3B C;  4MEY A;  1YNN A;  3RZO C;  1R9T C;  3M4O C;  4A3F K;  4A3L C;  1K83 C;  3GTK K;  4Q4Z A;  3GTP K;  2WAQ L;  4A3G C;  4BY1 K;  5TMC A;  2YU9 K;  4QIW D;  2JA6 C;  4C3I C;  2R92 C;  2NVT K;  3HOY K;  2CW0 A;  4C3J C;  3PO2 C;  5M3F K;  5IP9 K;  2JA5 C;  4LK0 A;  2PPB A;  3S16 C;  2PA8 L;  3H0G K;  2WB1 D;  5IYD K;  4A3C K;  4A3J K;  1TWC C;  3I4M C;  2R7Z C;  2O5J A;  5D4D A;  2NVQ K;  4YFN A;  3GTL K;  5FLM C;  4XSX A;  1HQM A;  3S17 C;  4X6A C;  3HOW C;  2B63 K;  5C4J K;  3HOV K;  4A3I C;  4C2M C;  4AYB D;  4G7H A;  4A3M K;  4BBR K;  5M5X K;  3S2D K;  3CQZ C;  4MEX A;  4A93 K;  1TWH K;  4OIN A;  2O5I A;  4BXX C;  5M3M K;  4BY7 K;  1TWF C;  4A3E C;  3GTO K;  3HOZ K;  4KN7 A;  1TWG K;  4A3D C;  3H3V L;  4A3K C;  2E2H K;  2WAQ D;  3S2H C;  5FJ8 K;  4C3H K;  4Q5S A;  4Y7N K;  1SFO K;  3GTQ K;  1I6H K;  4LJZ A;  3HOX K;  3RZD K;  4KN4 A;  3S1Q C;  3HOU K;  4OIO A;  3I4N C;  2E2J C;  5C3E C;  4G7O A;  2PA8 D;  1XPP A;  4OIQ A;  1Y1V C;  1TWA C;  2A68 A;  5IYC C;  2NVX K;  3M3Y K;  3S1M K;  4Y52 K;  4NOI A;  3S15 K;  3GTG K;  2A69 A;  2Y0S L;  4A3F C;  2JA8 K;  2E2I K;  5C44 K;  4BBS K;  3S1R K;  1Y1W K;  2BE5 A;  4BY1 C;  2YU9 C;  2NVY C;  3HOY C;  4A3L K;  2NVT C;  3S14 K;  5IP9 C;  4GZY A;  2R93 C;  1WCM K;  3H3V D;  2JA6 K;  1I3Q K;  5IYD C;  5IYB K;  3HKZ L;  3GTM K;  3S16 K;  3FKI K;  3GTL C;  1I6V A;  3EQL A;  3GTJ C;  2B63 C;  4XLN A;  4OIR A;  1I50 K;  3K7A K;  2JA7 K;  5M5Y K;  4BBR C;  5TMF A;  2VUM C;  4A93 C;  1TWH C;  5C4X K;  3HOW K;  1ZYR A;  3S1N C;  3GTO C;  1TWG C;  5IP7 K;  2A6E A;  2E2H C;  4C3H C;  3WOD A;  3GTQ C;  1I6H C;  4A3E K;  3PO3 K;  3HOX C;  5M5W K;  3GTK C;  4YG2 A;  4YFK A;  4OIP A;  3GTP C;  3RZO K;  3M4O K;  1R9T K;  4A3B K;  1K83 K;  3I4N K;  3HKZ D;  2NVX C;  4A3G K;  3GTG C;  4C3I K;  2R92 K;  2JA8 C;  4AYB L;  1TWA K;  5IYC K;  3H0G C;  4C3J K;  5C44 C;  4BBS C;  3S1R C;  4A3J C;  1Y1W C;  4A3C C;  3PO2 K;  2JA5 K;  1BDF A;  4LLG A;  2NVQ C;  3S14 C;  1TWC K;  3HOV C;  3S15 C;  2PMZ L;  3I4M K;  4XSZ A;  1WCM C;  5C4J C;  2NVY K;  2R7Z K;  4KMU A;  1I3Q C;  4ZH4 A;  4A3M C;  3S2D C;  5FLM K;  5IYB C;  4X6A K;  4QJV A;  3S17 K;  4MQ9 A;  2R93 K;  2Y0S D;  4BY7 C;  4C2M K;  4A3I K;  3GTM C;  3HOZ C;  4LK1 A;  3FKI C;  4QIW L;  3CQZ K;  4YFX A;  4BXX K;  4Y7N C;  1SFO C;  1I50 C;  4JK1 A;  3K7A C;  1TWF K;  2JA7 C;  2A6H A;  3RZD C;  1YNJ A;  4A3K K;  3HOU C;  3S2H K;  4A3D K;  4G7Z A;  3GTJ K;  5C4X C;  2WB1 L;  3DXJ A;  3S1Q K;  5IP7 C;  2VUM K;  1SMY A;  3M3Y C;  3S1M C;  5C3E K;  4Y52 C;  2E2J K;  3S1N K; 
#chains in the Genus database with same CATH topology
 4WJ3 M;  2E2I C;  1Y1V K;  2KQ1 A;  3A8I A;  3AQO A;  5L46 A;  1IW7 A;  3M4O C;  1R9T C;  4A3F K;  2CFA B;  1JOE A;  1K83 C;  4KC6 A;  3BP3 A;  3V4G A;  2WAQ L;  2YU9 K;  2R92 C;  5M3F K;  3A8J A;  3S16 C;  5JVH S;  2WB1 D;  4A3J K;  1TWC C;  2JA5 A;  4WJ4 A;  5D4D A;  2NVQ K;  3AD8 C;  5FLM C;  3L4K A;  3HOV K;  4X6A C;  4WIL A;  3HOW C;  4IO9 S;  4AYB D;  2ZJR S;  4G7H A;  2NVY A;  4A3M K;  4KAT A;  4MEX A;  1TWH K;  2O5I A;  3TFI A;  4BY7 K;  3GTO K;  1ZVU A;  3H3V L;  2E2H K;  3CQZ A;  4Q5S A;  4Y7N K;  3ERE D;  1J6W A;  4M1X A;  3I4N C;  3GTJ A;  4G7O A;  1DCP A;  1X31 C;  3OPF A;  4GTF A;  3TTG A;  1Y1V C;  2A68 A;  3VA7 A;  1F9N A;  3GTG K;  2V6U A;  4A3F C;  4P5A A;  1F7U A;  4BBS K;  1XZP B;  3S1R K;  1V5V A;  2YU9 C;  2W7V A;  4A3L K;  1IBA A;  3S14 K;  1IE0 A;  4PAA A;  3GTP A;  1J6V A;  5IYB K;  3BUE A;  5HL7 S;  3HKZ L;  4O2D A;  3GTM K;  2ZUE A;  4WCE S;  4LQY A;  1TWH C;  4WFB S;  3GTO C;  5IP7 K;  2E2H C;  1EQR A;  2RH6 A;  3WOD A;  5TJ3 A;  4A3E K;  1TWG A;  5JFE A;  5M5W K;  3GTK C;  4FZB A;  4YG2 A;  4YFK A;  4G0V A;  3RZO K;  1XXC A;  4DDQ A;  4A3G K;  3GTG C;  4GTD A;  3DLL S;  3SZY A;  3H0G C;  1PJ7 A;  4KB2 A;  4BBS C;  3S1R C;  4LR2 A;  4C45 A;  2GAH C;  1HI9 A;  2JA5 K;  4LLG A;  1BS2 A;  2FQT A;  3S14 C;  4RMF A;  1B4A A;  2NVY K;  2FQO A;  5IYB C;  4MQ9 A;  3JST A;  3GTM C;  2JA6 A;  3IPJ A;  2CFA A;  3CQZ K;  4XCH A;  1WIH A;  1EH1 A;  2KXY A;  1BJT A;  1J6X A;  3RZD C;  4A3K K;  3GTJ K;  4GT9 A;  1O2F B;  5IP7 C;  4KB4 A;  3S1N K;  1WOO A;  5CJ9 A;  3A8K A;  1DD5 A;  2PMZ D;  3CF5 S;  4MEY A;  1YNN A;  3RZO C;  3PIP S;  2ZJQ S;  3GTP K;  4A3G C;  4QIW D;  3HOY K;  2NVT K;  2CW0 A;  2JA5 C;  2PA8 L;  1TWA A;  5IYD K;  4A3C K;  3S15 K;  2B63 K;  5E68 A;  4WFA S;  4BBR K;  3S2D K;  3CQZ C;  1XZP A;  5M3M K;  2R93 A;  1TWG K;  4A3K C;  3GEE A;  2WAQ D;  4G0U A;  5FJ8 K;  4LJZ A;  4U67 S;  3HOU K;  1G51 A;  4OIO A;  5IOR A;  1ZXO A;  4OIQ A;  3M3Y K;  3S1M K;  4Y52 K;  3N0C A;  2A69 A;  2EBB A;  2Y0S L;  3FHZ A;  2BE5 A;  3HOY C;  2NVT C;  4P5B A;  1AB4 A;  3H3V D;  2JA6 K;  4KAS A;  2XCQ A;  3LPX A;  5IYD C;  1VRQ C;  1F93 A;  2P8T A;  1IL2 A;  2B63 C;  4XLN A;  4OIR A;  3N0B A;  1VGX A;  4BBR C;  2VUM C;  4GTL A;  3GSI A;  1TWG C;  2GAG C;  1IS1 A;  3PO3 K;  1XZQ A;  1SFO A;  4A3B K;  3GIR A;  3GTQ A;  4GTE A;  3HKZ D;  4KM9 A;  1XXB A;  4AYB L;  1TWA K;  5IYC K;  2NVX A;  4A3J C;  1B4B A;  2NVQ C;  2E2I A;  5CHP A;  4KMH A;  3HOV C;  1O27 A;  4FM9 A;  1O29 A;  4A3M C;  3G4A A;  2R93 K;  4A3I K;  4BY7 C;  1WCM A;  3SZZ A;  4C2M K;  1PJ6 A;  1F7V A;  4YFX A;  4Y7N C;  4IOC S;  4A3D K;  1YNJ A;  3FKI A;  3S2H K;  1TWC A;  1UV7 A;  1WOP A;  1I50 A;  2JA7 A;  1WQF A;  2E2J K;  5C3E K;  3PO3 C;  1JVI A;  4AH6 A;  4A3B C;  1O25 A;  3AD9 C;  4LOW A;  4GFQ A;  4A3L C;  1O26 A;  4GTB A;  2JH3 A;  1VJE A;  3N3Y A;  5TMC A;  1XZQ B;  2PPB A;  1PJ5 A;  4BLB A;  2O5J A;  3G4C A;  4XSX A;  1HQM A;  4GTC A;  4PAB A;  5C4J K;  4A3I C;  4C2M C;  1WSV A;  3FOF A;  2R7Z A;  5M5X K;  2XCR B;  4OIN A;  4A3E C;  3HOZ K;  4KN7 A;  4A3D C;  3AD7 C;  3S2H C;  2GSN A;  4C3H K;  1SFO K;  1EFW A;  3GTQ K;  1I6H K;  2KPU A;  1L0W A;  1TWF A;  3FOE A;  4KN4 A;  1VH2 A;  2XCO A;  3AQP A;  2E2J C;  5C3E C;  2PA8 D;  2NVX K;  3T01 A;  1GE9 A;  5JVG S;  4NOI A;  1USO A;  3CAG A;  2E2I K;  5C44 K;  2NVY C;  3GTK A;  3MML B;  4KAR A;  1WCM K;  3QX3 A;  3S16 K;  3FKI K;  3H0G A;  3NUH A;  3GTJ C;  1O28 A;  1I50 K;  3K7A K;  2JA7 K;  4KMD A;  5TMF A;  3GTL A;  3HOW K;  1ZYR A;  2L5N A;  3S1N C;  3S0X A;  1O2A A;  4WF9 S;  3OEP A;  2A6E A;  1J98 A;  1RU0 A;  4C3H C;  3GTQ C;  1I6H C;  2KWA A;  3GTP C;  3L4J A;  3I4N K;  2NVX C;  5EGH A;  2GSU A;  4GTA A;  4C3I K;  2V6S A;  4C3J K;  3PO2 K;  5C44 C;  1WQG A;  4A3C C;  3GEI A;  4P9S A;  3T00 A;  3I4M K;  3S15 C;  1Y1W A;  1WCM C;  2R7Z K;  2ZFZ A;  3TFJ A;  3S2D C;  3S17 K;  1WOS A;  4LK1 A;  1I3Q A;  3FKI C;  1FEU A;  1DCO A;  5IOT A;  4BXX K;  1WQH A;  1I50 C;  1TWF K;  3K7A C;  3LAP A;  2JA7 C;  2Y3P A;  2A6H A;  5HL8 A;  3HOU C;  1ISE A;  4G7Z A;  2WB1 L;  3S1Q K;  4G0W A;  1SMY A;  3M3Y C;  3S1M C;  4Y52 C;  4XLP A;  4QJV B;  4J3N A;  3HXA A;  3GTK K;  4Q4Z A;  4BY1 K;  1ZQ1 C;  2D6F C;  2JA6 C;  2PHC B;  4C3I C;  1R9T A;  4KMA A;  1K83 A;  4C3J C;  3PO2 C;  3GEH A;  5IP9 K;  4LK0 A;  2R92 A;  3H0G K;  3I4M C;  2ZUF A;  2R7Z C;  1VLO A;  4YFN A;  3GTL K;  3S17 C;  1YCL A;  4A93 K;  1IQ0 A;  4BXX C;  1JQW A;  1INN A;  1TWF C;  2L3U A;  3TFH A;  3HOX K;  3RZD K;  3S1Q C;  3T02 A;  2B63 A;  3ORE A;  1XPP A;  1TWA C;  5IYC C;  2VUM A;  1DCH A;  1USM A;  3GDZ A;  2JA8 K;  4WFN S;  1XXA A;  4KAW X;  1Y1V A;  1Y1W K;  3LYW A;  4BY1 C;  5IOS A;  1BGW A;  5DM7 S;  5HQH A;  5EGE A;  5IP9 C;  1EI6 A;  4GZY A;  2R93 C;  2YU9 A;  3PIO S;  1I3Q K;  2GSO A;  3LAJ A;  3GTL C;  1I6V A;  3EQL A;  5DM6 S;  3ADA C;  5M5Y K;  1YX2 A;  1ZBS A;  4A93 C;  5C4X K;  4BKW A;  1WSR A;  1O2B A;  2ZJP S;  3AH5 A;  1TWH A;  3GTO A;  3HOX C;  2E2H A;  4OIP A;  1O24 A;  3M4O K;  1R9T K;  4BLA A;  1WOR A;  1K83 K;  3Q3Q A;  2R92 K;  2JA8 C;  5JVO A;  1Y1W C;  1EK8 A;  4KDD A;  1BDF A;  3GTG A;  2RGR A;  1TWC K;  2PMZ L;  4IOA S;  4XSZ A;  5C4J C;  4KMU A;  3BP8 C;  1I3Q C;  4ZH4 A;  5IOQ A;  1KQ4 A;  5FLM K;  4X6A K;  4QJV A;  1C0A A;  2Y0S D;  2P5M A;  2V6T A;  3HOZ C;  4QIW L;  4ILD A;  1SFO C;  4JK1 A;  3GTM A;  5C4X C;  4KM8 A;  3DXJ A;  2VUM K; 
#chains in the Genus database with same CATH homology
 3PO3 C;  4XLP A;  2E2I C;  1Y1V K;  2PMZ D;  4QJV B;  1IW7 A;  4A3B C;  4MEY A;  1YNN A;  3RZO C;  1R9T C;  3M4O C;  4A3F K;  4A3L C;  1K83 C;  3GTK K;  4Q4Z A;  3GTP K;  2WAQ L;  4A3G C;  4BY1 K;  5TMC A;  2YU9 K;  4QIW D;  2JA6 C;  4C3I C;  2R92 C;  2NVT K;  3HOY K;  2CW0 A;  4C3J C;  3PO2 C;  5M3F K;  5IP9 K;  2JA5 C;  4LK0 A;  2PPB A;  3S16 C;  2PA8 L;  3H0G K;  2WB1 D;  5IYD K;  4A3C K;  4A3J K;  1TWC C;  3I4M C;  2R7Z C;  2O5J A;  5D4D A;  2NVQ K;  4YFN A;  3GTL K;  5FLM C;  4XSX A;  1HQM A;  3S17 C;  4X6A C;  3HOW C;  2B63 K;  5C4J K;  3HOV K;  4A3I C;  4C2M C;  4AYB D;  4G7H A;  4A3M K;  4BBR K;  5M5X K;  3S2D K;  3CQZ C;  4MEX A;  4A93 K;  1TWH K;  4OIN A;  2O5I A;  4BXX C;  5M3M K;  4BY7 K;  1TWF C;  4A3E C;  3GTO K;  3HOZ K;  4KN7 A;  1TWG K;  4A3D C;  3H3V L;  4A3K C;  2E2H K;  2WAQ D;  3S2H C;  5FJ8 K;  4C3H K;  4Q5S A;  4Y7N K;  1SFO K;  3GTQ K;  1I6H K;  4LJZ A;  3HOX K;  3RZD K;  4KN4 A;  3S1Q C;  3HOU K;  4OIO A;  3I4N C;  2E2J C;  5C3E C;  4G7O A;  2PA8 D;  1XPP A;  4OIQ A;  1Y1V C;  1TWA C;  2A68 A;  5IYC C;  2NVX K;  3M3Y K;  3S1M K;  4Y52 K;  4NOI A;  3S15 K;  3GTG K;  2A69 A;  2Y0S L;  4A3F C;  2JA8 K;  2E2I K;  5C44 K;  4BBS K;  3S1R K;  1Y1W K;  2BE5 A;  4BY1 C;  2YU9 C;  2NVY C;  3HOY C;  4A3L K;  2NVT C;  3S14 K;  5IP9 C;  4GZY A;  2R93 C;  1WCM K;  3H3V D;  2JA6 K;  1I3Q K;  5IYD C;  5IYB K;  3HKZ L;  3GTM K;  3S16 K;  3FKI K;  3GTL C;  1I6V A;  3EQL A;  3GTJ C;  2B63 C;  4XLN A;  4OIR A;  1I50 K;  3K7A K;  2JA7 K;  5M5Y K;  4BBR C;  5TMF A;  2VUM C;  4A93 C;  1TWH C;  5C4X K;  3HOW K;  1ZYR A;  3S1N C;  3GTO C;  1TWG C;  5IP7 K;  2A6E A;  2E2H C;  4C3H C;  3WOD A;  3GTQ C;  1I6H C;  4A3E K;  3PO3 K;  3HOX C;  5M5W K;  3GTK C;  4YG2 A;  4YFK A;  4OIP A;  3GTP C;  3RZO K;  3M4O K;  1R9T K;  4A3B K;  1K83 K;  3I4N K;  3HKZ D;  2NVX C;  4A3G K;  3GTG C;  4C3I K;  2R92 K;  2JA8 C;  4AYB L;  1TWA K;  5IYC K;  3H0G C;  4C3J K;  5C44 C;  4BBS C;  3S1R C;  4A3J C;  1Y1W C;  4A3C C;  3PO2 K;  2JA5 K;  1BDF A;  4LLG A;  2NVQ C;  3S14 C;  1TWC K;  3HOV C;  3S15 C;  2PMZ L;  3I4M K;  4XSZ A;  1WCM C;  5C4J C;  2NVY K;  2R7Z K;  4KMU A;  1I3Q C;  4ZH4 A;  4A3M C;  3S2D C;  5FLM K;  5IYB C;  4X6A K;  4QJV A;  3S17 K;  4MQ9 A;  2R93 K;  2Y0S D;  4BY7 C;  4C2M K;  4A3I K;  3GTM C;  3HOZ C;  4LK1 A;  3FKI C;  4QIW L;  3CQZ K;  4YFX A;  4BXX K;  4Y7N C;  1SFO C;  1I50 C;  4JK1 A;  3K7A C;  1TWF K;  2JA7 C;  2A6H A;  3RZD C;  1YNJ A;  4A3K K;  3HOU C;  3S2H K;  4A3D K;  4G7Z A;  3GTJ K;  5C4X C;  2WB1 L;  3DXJ A;  3S1Q K;  5IP7 C;  2VUM K;  1SMY A;  3M3Y C;  3S1M C;  5C3E K;  4Y52 C;  2E2J K;  3S1N K; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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