3CQZC

Crystal structure of 10 subunit rna polymerase ii in complex with the inhibitor alpha-amanitin
Total Genus 58
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
58
sequence length
265
structure length
265
Chain Sequence
EEGPQVKIREASKDNVDFILSNVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLADEFIAHRLGLIPLQSMDIEQLEYSRDCFCEDHCDKCSVVLTLQAFGESESTTNVYSKDLVIVSNLMGRNIGHPIIQDKEGNGVLICKLRKGQELKLTCVAKKGIAKEHAKWGPAAAIEFEYDPWNKLKHTDYWYEQDSAKEWPQSKNCEYEDPPNEGDPFDYKAQADTFYMNVESVGSIPVDQVVVRGIDTLQKKVASILLALTQMDQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The RNA Polymerase II Trigger Loop Functions in Substrate Selection and is Directly Targeted by Alpha-Amanitin.
pubmed doi rcsb
molecule tags Transcription/toxin
molecule keywords DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1
total genus 58
structure length 265
sequence length 265
ec nomenclature
pdb deposition date 2008-04-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF01000 RNA_pol_A_bac RNA polymerase Rpb3/RpoA insert domain
C PF01193 RNA_pol_L RNA polymerase Rpb3/Rpb11 dimerisation domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.120.12 Mainly Beta Beta Complex RNA Polymerase Alpha Subunit; Chain A, domain 2 DNA-directed RNA polymerase, insert domain 3cqzC02
3.30.1360.10 Alpha Beta 2-Layer Sandwich Gyrase A; domain 2 RNA polymerase, RBP11-like subunit 3cqzC01
4A3DK 3HOZC 3S1QC 4A3EK 5M5WK 4ZH4A 4C3JK 2A69A 5IP7C 2O5IA 1TWGK 4KN4A 3I4NC 5M5YK 4LK0A 4A3GC 3I4MC 1TWFK 3GTJC 4A3FK 2PPBA 3CQZC 4Y7NK 3GTLK 2PMZL 3HOZK 4OIQA 3GTMK 4YFXA 1SFOC 4OINA 3HOWC 1R9TC 1K83C 2JA7C 3FKIK 3M3YK 4XLPA 2E2HK 5D4DA 1SMYA 4BBSK 4A3CK 1YNNA 4KN7A 2JA6K 4BXXK 3PO3K 1SFOK 2R93C 3S17C 2A68A 4JK1A 4QIWL 4C2MK 3HOYK 2Y0SD 4A3IK 4Y52C 4Y7NC 1TWCK 2JA5C 4X6AC 4BBSC 3M4OC 4A3CC 4Q4ZA 2JA8C 4BXXC 5C3EC 1I3QK 1I50K 1R9TK 3FKIC 3HOXC 3GTPK 1BDFA 4YG2A 2YU9C 4BBRC 4A3LC 3HKZD 4A3MK 3GTKC 3HKZL 2VUMK 3M4OK 4GZYA 1Y1WC 4A3JC 3S14C 5C4JK 3S15K 4A93K 4G7HA 4A3IC 1TWCC 1XPPA 4Y52K 2NVQC 4AYBD 3EQLA 4BY7C 3S2HC 1ZYRA 3GTOK 1WCMC 4A3MC 3HOXK 5C4JC 1I6VA 3K7AC 3S15C 3H3VD 4Q5SA 5C44C 2BE5A 4BBRK 4XSXA 4A3LK 4BY7K 4LK1A 3S2HK 2B63K 4XLNA 1TWAC 2NVXK 1YNJA 3RZDC 2NVQK 3GTOC 2A6HA 2O5JA 2B63C 4MEYA 4LJZA 4MQ9A 4A3KK 2R92C 4QJVB 5C44K 4A3BK 5M5XK 4BY1C 5IYBK 3GTMC 5IYDC 3S1RC 3HOWK 2NVXC 1K83K 4A3KC 1TWAK 3RZDK 2JA7K 2R92K 2R93K 3HOYC 3HOVC 2JA6C 2JA5K 3GTQC 5IYBC 4C2MC 2PA8D 5IP7K 4A3BC 5FLMK 4A3DC 5TMCA 2E2IK 4MEXA 4C3IK 3GTLC 3GTJK 3S2DK 3CQZK 1I3QC 5C3EK 5TMFA 4OIOA 2WB1D 3GTQK 3S16K 2E2JK 3I4NK 4A3JK 3S14K 3HOVK 3PO2K 4AYBL 2VUMC 2YU9K 4OIPA 2E2IC 2WAQD 3DXJA 1TWHC 3RZOC 3S2DC 2CW0A 4A93C 1Y1WK 3PO3C 3H3VL 3S16C 2E2JC 4LLGA 3K7AK 2E2HC 2PA8L 4C3IC 5M3MK 5C4XC 4X6AK 1TWHK 3RZOK 2JA8K 5IYCK 2NVYC 1I50C 4YFNA 3GTGK 3S17K 3PO2C 1Y1VC 2Y0SL 4KMUA 5IP9C 2PMZD 3S1MK 4C3HC 2WAQL 2R7ZK 5C4XK 3GTKK 4G7ZA 2NVYK 3GTPC 4YFKA 5IYCC 3HOUK 3S1NK 3H0GK 2WB1L 4BY1K 5IP9K 4QJVA 2NVTC 1I6HC 2R7ZC 1WCMK 3WODA 3GTGC 4C3HK 5FJ8K 5M3FK 1IW7A 4QIWD 2A6EA 1Y1VK 4A3GK 3S1QK 3S1MC 1TWFC 4A3EC 4OIRA 4A3FC 4G7OA 3I4MK 5IYDK 1HQMA 4XSZA 4NOIA 4C3JC 3S1RK 1TWGC 2NVTK 1I6HK 3HOUC 3S1NC 3H0GC 5FLMC 3M3YC
chains in the Genus database with same CATH superfamily
1VGXA 2XCRB 2GSNA 4ZH4A 1WSRA 2E2HA 5IP7C 4KN4A 4A3FK 4WFAS 1RU0A 3GEEA 3GTMK 1R9TC 4J3NA 3FOEA 3M3YK 3A8KA 4DDQA 5HL7S 5D4DA 1TWGA 3LYWA 3FHZA 3PO3K 2A68A 1F7VA 1IBAA 2Y0SD 1WQGA 1TWCK 4BBSC 2W7VA 4BXXC 3GTPK 4IOCS 1TWAA 1V5VA 1USMA 2R92A 3HKZD 1Y1WC 4A93K 4A3IC 4PABA 4Y52K 2ZJQS 2NVQC 1R9TA 5TJ3A 1ZYRA 4A3MC 4AH6A 3H3VD 1WQHA 1O24A 1O26A 4LK1A 3SZZA 1BGWA 1EFWA 3DLLS 3RZDC 1IS1A 2O5JA 4MEYA 3G4CA 4U67S 5M5XK 4PAAA 1I50A 4BY1C 3AD8C 4P9SA 4KDDA 5IYDC 1K83K 5EGHA 2FQOA 4GT9A 1F9NA 4A3BC 5FLMK 4KB4A 4C3IK 2RGRA 3GTLC 3GTJK 1J6VA 5C3EK 2E2JK 3HOVK 3T00A 1O28A 2XCOA 3AQOA 3PO3C 3ERED 3H3VL 3JSTA 4LLGA 2E2HC 2GSUA 4C3IC 1WORA 4ILDA 4X6AK 5C4XC 3RZOK 1HI9A 2NVYC 3GTGK 3PO2C 4KMUA 1BS2A 1O2BA 3FOFA 5JVHS 2R93A 2R7ZK 2WAQL 1PJ6A 1XZPA 3GTKK 3NUHA 4YFKA 3QX3A 1TWHA 4QJVA 1I6HC 4C3HK 3GTGC 3AH5A 1I3QA 3S1MC 2Y3PA 3S0XA 4G7OA 4XSZA 5IOQA 4NOIA 3S1RK 2NVTK 3OPFA 3A8JA 3S1NC 3H0GC 3LPXA 2V6UA 1L0WA 2A69A 2O5IA 1TWGK 5M5YK 1G51A 3GTJC 3GTLK 2PPBA 3MMLB 4Y7NK 4WCES 4YFXA 1SFOC 3HOWC 2JA7C 3FKIK 4XLPA 4WFNS 1SMYA 1X31C 4BBSK 2P8TA 1EI6A 2V6TA 4P5AA 1VLOA 5DM6S 3H0GA 2R93C 4C2MK 3HOYK 3AD7C 4GTLA 4A3IK 1J6XA 2GAGC 3GSIA 3VA7A 1R9TK 3HOXC 2L3UA 4A3LC 3HKZL 1YX2A 5E68A 4A3JC 3S14C 4BLAA 4LOWA 5C4JC 1IQ0A 3PIPS 2KQ1A 1DD5A 4BBRK 4XSXA 3S2HK 2NVXK 1YNJA 3V4GA 1WIHA 2A6HA 3PIOS 1TWCA 4LJZA 3BP3A 3L4JA 4BLBA 4FZBA 1F93A 4QJVB 4KMAA 3GDZA 3GTPA 1TWAK 3TTGA 1UV7A 2R92K 3HOVC 3AD9C 2KPUA 5IYBC 1DCOA 2PA8D 2E2IK 4MEXA 2KWAA 3S2DK 1I3QC 2ZUEA 4OIOA 1ZXOA 4O2DA 2VUMC 3GTGA 4KMHA 1AB4A 3DXJA 1TWHC 3S2DC 4A93C 1Y1WK 3CQZA 3GTQA 4WF9S 1TWHK 3S17K 1I50C 1O2FB 2Y0SL 1K83A 4FM9A 5IP9C 2PMZD 1YCLA 4C3HC 4KAWX 1XXCA 5C4XK 3IPJA 4G7ZA 2JA6A 3HOUK 4IOAS 2WB1L 5IOTA 4RMFA 3TFHA 2R7ZC 5M3FK 3WODA 5FJ8K 4WJ3M 3GEIA 1IW7A 4QIWD 1IL2A 1BJTA 1C0AA 1TWFC 4A3EC 4OIRA 2NVYA 3GTLA 2VUMA 1WCMA 5FLMC 4A3DK 3S1QC 3FKIA 4A3EK 4KB2A 4KATA 2ZJRS 3I4NC 2ZFZA 4A3GC 3I4MC 4BKWA 5DM7S 3CQZC 4G0UA 3HOZK 4OIQA 4KM9A 2XCQA 1O2AA 2R7ZA 4A3CK 1TWFA 1USOA 4GFQA 4JK1A 4XCHA 2JA5C 3M4OC 4A3CC 2JA8C 1I3QK 3T02A 1JOEA 4P5BA 3CF5S 1SFOA 2YU9C 4BBRC 4A3MK 3GTKC 3M4OK 1VJEA 3T01A 3S15K 2ZJPS 1ZVUA 4G7HA 4IO9S 1INNA 1EQRA 1VRQC 5CJ9A 2NVXA 3GTOK 5IOSA 3S15C 1I6VA 3K7AC 1ZQ1C 4GTCA 4Q5SA 5C44C 2BE5A 4A3LK 4BY7K 2B63K 4XLNA 1WOOA 2NVQK 3GTOC 4WILA 4KMDA 2ZUFA 2CFAB 4MQ9A 4M1XA 2R92C 3L4KA 4A3KK 5HQHA 5C44K 5IYBK 3GTMC 4GTBA 3ADAC 3SZYA 3S1RC 1J98A 2JA7K 4A3KC 2EBBA 3HOYC 1WOPA 2GAHC 1B4AA 2JA6C 2JA5K 5JVGS 1Y1WA 5TMCA 1Y1VA 3CQZK 5HL8A 3GTQK 3S16K 3I4NK 4AYBL 2YU9K 3Q3QA 4GTFA 2WAQD 3RZOC 2CW0A 2FQTA 5EGEA 1DCHA 3S16C 3K7AK 3CAGA 3OEPA 5M3MK 4KM8A 4YFNA 3GEHA 3N3YA 4KARA 3GTMA 2P5MA 1JQWA 1GE9A 2NVYK 1IE0A 5IYCC 3S1NK 4C45A 5IP9K 1WCMK 1XZQB 2V6SA 2E2IA 5L46A 1VH2A 3TFJA 3S1QK 3I4MK 1HQMA 4C3JC 3AQPA 3HXAA 1ISEA 5IYCK 3M3YC 2PHCB 3HOZC 5M5WK 4C3JK 2JH3A 4LK0A 1TWFK 2PMZL 2L5NA 3BP8C 4OINA 1KQ4A 1K83C 1XZQA 2E2HK 1YNNA 4KN7A 2JA6K 4BXXK 1XXBA 1SFOK 4QIWL 3S17C 2GSOA 4Y52C 4Y7NC 4X6AC 4Q4ZA 5C3EC 1I50K 4G0VA 1DCPA 3FKIC 4KC6A 3GTOA 1BDFA 4YG2A 1WOSA 1WSVA 2VUMK 4GZYA 5C4JK 1XPPA 1TWCC 3N0BA 2B63A 4AYBD 3EQLA 4BY7C 4LQYA 3S2HC 1WCMC 1JVIA 3HOXK 1O25A 3GTJA 1EK8A 1EH1A 1O27A 1TWAC 3BUEA 2B63C 4KASA 2JA5A 4A3BK 1WQFA 1PJ5A 3HOWK 2NVXC 5CHPA 3LAJA 3RZDK 2R93K 3GTKA 4WJ4A 3GTQC 3OREA 2YU9A 4C2MC 1B4BA 3A8IA 5IP7K 4A3DC 1J6WA 3GIRA 1F7UA 5TMFA 2WB1D 4GTEA 4GTAA 4A3JK 3S14K 1O29A 3PO2K 1XZPB 4LR2A 1ZBSA 4OIPA 2E2IC 2E2JC 2PA8L 4G0WA 1FEUA 5JFEA 2KXYA 3G4AA 2JA8K 4WFBS 3N0CA 1Y1VC 2JA7A 3S1MK 3LAPA 3GTPC 5IORA 5JVOA 2CFAA 3H0GK 2D6FC 4BY1K 2NVTC 1PJ7A 1Y1VK 2A6EA 2RH6A 3TFIA 4A3GK 4A3FC 5IYDK 4GTDA 1TWGC 1I6HK 1XXAA 3HOUC
chains in the Genus database with same CATH topology
4A3DK 3HOZC 3S1QC 4A3EK 5M5WK 4ZH4A 4C3JK 2A69A 5IP7C 2O5IA 1TWGK 4KN4A 3I4NC 5M5YK 4LK0A 4A3GC 3I4MC 1TWFK 3GTJC 4A3FK 2PPBA 3CQZC 4Y7NK 3GTLK 2PMZL 3HOZK 4OIQA 3GTMK 4YFXA 1SFOC 4OINA 3HOWC 1R9TC 1K83C 2JA7C 3FKIK 3M3YK 4XLPA 2E2HK 5D4DA 1SMYA 4BBSK 4A3CK 1YNNA 4KN7A 2JA6K 4BXXK 3PO3K 1SFOK 2R93C 3S17C 2A68A 4JK1A 4QIWL 4C2MK 3HOYK 2Y0SD 4A3IK 4Y52C 4Y7NC 1TWCK 2JA5C 4X6AC 4BBSC 3M4OC 4A3CC 4Q4ZA 2JA8C 4BXXC 5C3EC 1I3QK 1I50K 1R9TK 3FKIC 3HOXC 3GTPK 1BDFA 4YG2A 2YU9C 4BBRC 4A3LC 3HKZD 4A3MK 3GTKC 3HKZL 2VUMK 3M4OK 4GZYA 1Y1WC 4A3JC 3S14C 5C4JK 3S15K 4A93K 4G7HA 4A3IC 1TWCC 1XPPA 4Y52K 2NVQC 4AYBD 3EQLA 4BY7C 3S2HC 1ZYRA 3GTOK 1WCMC 4A3MC 3HOXK 5C4JC 1I6VA 3K7AC 3S15C 3H3VD 4Q5SA 5C44C 2BE5A 4BBRK 4XSXA 4A3LK 4BY7K 4LK1A 3S2HK 2B63K 4XLNA 1TWAC 2NVXK 1YNJA 3RZDC 2NVQK 3GTOC 2A6HA 2O5JA 2B63C 4MEYA 4LJZA 4MQ9A 4A3KK 2R92C 4QJVB 5C44K 4A3BK 5M5XK 4BY1C 5IYBK 3GTMC 5IYDC 3S1RC 3HOWK 2NVXC 1K83K 4A3KC 1TWAK 3RZDK 2JA7K 2R92K 2R93K 3HOYC 3HOVC 2JA6C 2JA5K 3GTQC 5IYBC 4C2MC 2PA8D 5IP7K 4A3BC 5FLMK 4A3DC 5TMCA 2E2IK 4MEXA 4C3IK 3GTLC 3GTJK 3S2DK 3CQZK 1I3QC 5C3EK 5TMFA 4OIOA 2WB1D 3GTQK 3S16K 2E2JK 3I4NK 4A3JK 3S14K 3HOVK 3PO2K 4AYBL 2VUMC 2YU9K 4OIPA 2E2IC 2WAQD 3DXJA 1TWHC 3RZOC 3S2DC 2CW0A 4A93C 1Y1WK 3PO3C 3H3VL 3S16C 2E2JC 4LLGA 3K7AK 2E2HC 2PA8L 4C3IC 5M3MK 5C4XC 4X6AK 1TWHK 3RZOK 2JA8K 5IYCK 2NVYC 1I50C 4YFNA 3GTGK 3S17K 3PO2C 1Y1VC 2Y0SL 4KMUA 5IP9C 2PMZD 3S1MK 4C3HC 2WAQL 2R7ZK 5C4XK 3GTKK 4G7ZA 2NVYK 3GTPC 4YFKA 5IYCC 3HOUK 3S1NK 3H0GK 2WB1L 4BY1K 5IP9K 4QJVA 2NVTC 1I6HC 2R7ZC 1WCMK 3WODA 3GTGC 4C3HK 5FJ8K 5M3FK 1IW7A 4QIWD 2A6EA 1Y1VK 4A3GK 3S1QK 3S1MC 1TWFC 4A3EC 4OIRA 4A3FC 4G7OA 3I4MK 5IYDK 1HQMA 4XSZA 4NOIA 4C3JC 3S1RK 1TWGC 2NVTK 1I6HK 3HOUC 3S1NC 3H0GC 5FLMC 3M3YC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4A3D K;  3HOZ C;  3S1Q C;  4A3E K;  5M5W K;  4ZH4 A;  4C3J K;  2A69 A;  5IP7 C;  2O5I A;  1TWG K;  4KN4 A;  3I4N C;  5M5Y K;  4LK0 A;  4A3G C;  3I4M C;  1TWF K;  3GTJ C;  4A3F K;  2PPB A;  3CQZ C;  4Y7N K;  3GTL K;  2PMZ L;  3HOZ K;  4OIQ A;  3GTM K;  4YFX A;  1SFO C;  4OIN A;  3HOW C;  1R9T C;  1K83 C;  2JA7 C;  3FKI K;  3M3Y K;  4XLP A;  2E2H K;  5D4D A;  1SMY A;  4BBS K;  4A3C K;  1YNN A;  4KN7 A;  2JA6 K;  4BXX K;  3PO3 K;  1SFO K;  2R93 C;  3S17 C;  2A68 A;  4JK1 A;  4QIW L;  4C2M K;  3HOY K;  2Y0S D;  4A3I K;  4Y52 C;  4Y7N C;  1TWC K;  2JA5 C;  4X6A C;  4BBS C;  3M4O C;  4A3C C;  4Q4Z A;  2JA8 C;  4BXX C;  5C3E C;  1I3Q K;  1I50 K;  1R9T K;  3FKI C;  3HOX C;  3GTP K;  1BDF A;  4YG2 A;  2YU9 C;  4BBR C;  4A3L C;  3HKZ D;  4A3M K;  3GTK C;  3HKZ L;  2VUM K;  3M4O K;  4GZY A;  1Y1W C;  4A3J C;  3S14 C;  5C4J K;  3S15 K;  4A93 K;  4G7H A;  4A3I C;  1TWC C;  1XPP A;  4Y52 K;  2NVQ C;  4AYB D;  3EQL A;  4BY7 C;  3S2H C;  1ZYR A;  3GTO K;  1WCM C;  4A3M C;  3HOX K;  5C4J C;  1I6V A;  3K7A C;  3S15 C;  3H3V D;  4Q5S A;  5C44 C;  2BE5 A;  4BBR K;  4XSX A;  4A3L K;  4BY7 K;  4LK1 A;  3S2H K;  2B63 K;  4XLN A;  1TWA C;  2NVX K;  1YNJ A;  3RZD C;  2NVQ K;  3GTO C;  2A6H A;  2O5J A;  2B63 C;  4MEY A;  4LJZ A;  4MQ9 A;  4A3K K;  2R92 C;  4QJV B;  5C44 K;  4A3B K;  5M5X K;  4BY1 C;  5IYB K;  3GTM C;  5IYD C;  3S1R C;  3HOW K;  2NVX C;  1K83 K;  4A3K C;  1TWA K;  3RZD K;  2JA7 K;  2R92 K;  2R93 K;  3HOY C;  3HOV C;  2JA6 C;  2JA5 K;  3GTQ C;  5IYB C;  4C2M C;  2PA8 D;  5IP7 K;  4A3B C;  5FLM K;  4A3D C;  5TMC A;  2E2I K;  4MEX A;  4C3I K;  3GTL C;  3GTJ K;  3S2D K;  3CQZ K;  1I3Q C;  5C3E K;  5TMF A;  4OIO A;  2WB1 D;  3GTQ K;  3S16 K;  2E2J K;  3I4N K;  4A3J K;  3S14 K;  3HOV K;  3PO2 K;  4AYB L;  2VUM C;  2YU9 K;  4OIP A;  2E2I C;  2WAQ D;  3DXJ A;  1TWH C;  3RZO C;  3S2D C;  2CW0 A;  4A93 C;  1Y1W K;  3PO3 C;  3H3V L;  3S16 C;  2E2J C;  4LLG A;  3K7A K;  2E2H C;  2PA8 L;  4C3I C;  5M3M K;  5C4X C;  4X6A K;  1TWH K;  3RZO K;  2JA8 K;  5IYC K;  2NVY C;  1I50 C;  4YFN A;  3GTG K;  3S17 K;  3PO2 C;  1Y1V C;  2Y0S L;  4KMU A;  5IP9 C;  2PMZ D;  3S1M K;  4C3H C;  2WAQ L;  2R7Z K;  5C4X K;  3GTK K;  4G7Z A;  2NVY K;  3GTP C;  4YFK A;  5IYC C;  3HOU K;  3S1N K;  3H0G K;  2WB1 L;  4BY1 K;  5IP9 K;  4QJV A;  2NVT C;  1I6H C;  2R7Z C;  1WCM K;  3WOD A;  3GTG C;  4C3H K;  5FJ8 K;  5M3F K;  1IW7 A;  4QIW D;  2A6E A;  1Y1V K;  4A3G K;  3S1Q K;  3S1M C;  1TWF C;  4A3E C;  4OIR A;  4A3F C;  4G7O A;  3I4M K;  5IYD K;  1HQM A;  4XSZ A;  4NOI A;  4C3J C;  3S1R K;  1TWG C;  2NVT K;  1I6H K;  3HOU C;  3S1N C;  3H0G C;  5FLM C;  3M3Y C; 
#chains in the Genus database with same CATH topology
 1VGX A;  2XCR B;  2GSN A;  4ZH4 A;  1WSR A;  2E2H A;  5IP7 C;  4KN4 A;  4A3F K;  4WFA S;  1RU0 A;  3GEE A;  3GTM K;  1R9T C;  4J3N A;  3FOE A;  3M3Y K;  3A8K A;  4DDQ A;  5HL7 S;  5D4D A;  1TWG A;  3LYW A;  3FHZ A;  3PO3 K;  2A68 A;  1F7V A;  1IBA A;  2Y0S D;  1WQG A;  1TWC K;  4BBS C;  2W7V A;  4BXX C;  3GTP K;  4IOC S;  1TWA A;  1V5V A;  1USM A;  2R92 A;  3HKZ D;  1Y1W C;  4A93 K;  4A3I C;  4PAB A;  4Y52 K;  2ZJQ S;  2NVQ C;  1R9T A;  5TJ3 A;  1ZYR A;  4A3M C;  4AH6 A;  3H3V D;  1WQH A;  1O24 A;  1O26 A;  4LK1 A;  3SZZ A;  1BGW A;  1EFW A;  3DLL S;  3RZD C;  1IS1 A;  2O5J A;  4MEY A;  3G4C A;  4U67 S;  5M5X K;  4PAA A;  1I50 A;  4BY1 C;  3AD8 C;  4P9S A;  4KDD A;  5IYD C;  1K83 K;  5EGH A;  2FQO A;  4GT9 A;  1F9N A;  4A3B C;  5FLM K;  4KB4 A;  4C3I K;  2RGR A;  3GTL C;  3GTJ K;  1J6V A;  5C3E K;  2E2J K;  3HOV K;  3T00 A;  1O28 A;  2XCO A;  3AQO A;  3PO3 C;  3ERE D;  3H3V L;  3JST A;  4LLG A;  2E2H C;  2GSU A;  4C3I C;  1WOR A;  4ILD A;  4X6A K;  5C4X C;  3RZO K;  1HI9 A;  2NVY C;  3GTG K;  3PO2 C;  4KMU A;  1BS2 A;  1O2B A;  3FOF A;  5JVH S;  2R93 A;  2R7Z K;  2WAQ L;  1PJ6 A;  1XZP A;  3GTK K;  3NUH A;  4YFK A;  3QX3 A;  1TWH A;  4QJV A;  1I6H C;  4C3H K;  3GTG C;  3AH5 A;  1I3Q A;  3S1M C;  2Y3P A;  3S0X A;  4G7O A;  4XSZ A;  5IOQ A;  4NOI A;  3S1R K;  2NVT K;  3OPF A;  3A8J A;  3S1N C;  3H0G C;  3LPX A;  2V6U A;  1L0W A;  2A69 A;  2O5I A;  1TWG K;  5M5Y K;  1G51 A;  3GTJ C;  3GTL K;  2PPB A;  3MML B;  4Y7N K;  4WCE S;  4YFX A;  1SFO C;  3HOW C;  2JA7 C;  3FKI K;  4XLP A;  4WFN S;  1SMY A;  1X31 C;  4BBS K;  2P8T A;  1EI6 A;  2V6T A;  4P5A A;  1VLO A;  5DM6 S;  3H0G A;  2R93 C;  4C2M K;  3HOY K;  3AD7 C;  4GTL A;  4A3I K;  1J6X A;  2GAG C;  3GSI A;  3VA7 A;  1R9T K;  3HOX C;  2L3U A;  4A3L C;  3HKZ L;  1YX2 A;  5E68 A;  4A3J C;  3S14 C;  4BLA A;  4LOW A;  5C4J C;  1IQ0 A;  3PIP S;  2KQ1 A;  1DD5 A;  4BBR K;  4XSX A;  3S2H K;  2NVX K;  1YNJ A;  3V4G A;  1WIH A;  2A6H A;  3PIO S;  1TWC A;  4LJZ A;  3BP3 A;  3L4J A;  4BLB A;  4FZB A;  1F93 A;  4QJV B;  4KMA A;  3GDZ A;  3GTP A;  1TWA K;  3TTG A;  1UV7 A;  2R92 K;  3HOV C;  3AD9 C;  2KPU A;  5IYB C;  1DCO A;  2PA8 D;  2E2I K;  4MEX A;  2KWA A;  3S2D K;  1I3Q C;  2ZUE A;  4OIO A;  1ZXO A;  4O2D A;  2VUM C;  3GTG A;  4KMH A;  1AB4 A;  3DXJ A;  1TWH C;  3S2D C;  4A93 C;  1Y1W K;  3CQZ A;  3GTQ A;  4WF9 S;  1TWH K;  3S17 K;  1I50 C;  1O2F B;  2Y0S L;  1K83 A;  4FM9 A;  5IP9 C;  2PMZ D;  1YCL A;  4C3H C;  4KAW X;  1XXC A;  5C4X K;  3IPJ A;  4G7Z A;  2JA6 A;  3HOU K;  4IOA S;  2WB1 L;  5IOT A;  4RMF A;  3TFH A;  2R7Z C;  5M3F K;  3WOD A;  5FJ8 K;  4WJ3 M;  3GEI A;  1IW7 A;  4QIW D;  1IL2 A;  1BJT A;  1C0A A;  1TWF C;  4A3E C;  4OIR A;  2NVY A;  3GTL A;  2VUM A;  1WCM A;  5FLM C;  4A3D K;  3S1Q C;  3FKI A;  4A3E K;  4KB2 A;  4KAT A;  2ZJR S;  3I4N C;  2ZFZ A;  4A3G C;  3I4M C;  4BKW A;  5DM7 S;  3CQZ C;  4G0U A;  3HOZ K;  4OIQ A;  4KM9 A;  2XCQ A;  1O2A A;  2R7Z A;  4A3C K;  1TWF A;  1USO A;  4GFQ A;  4JK1 A;  4XCH A;  2JA5 C;  3M4O C;  4A3C C;  2JA8 C;  1I3Q K;  3T02 A;  1JOE A;  4P5B A;  3CF5 S;  1SFO A;  2YU9 C;  4BBR C;  4A3M K;  3GTK C;  3M4O K;  1VJE A;  3T01 A;  3S15 K;  2ZJP S;  1ZVU A;  4G7H A;  4IO9 S;  1INN A;  1EQR A;  1VRQ C;  5CJ9 A;  2NVX A;  3GTO K;  5IOS A;  3S15 C;  1I6V A;  3K7A C;  1ZQ1 C;  4GTC A;  4Q5S A;  5C44 C;  2BE5 A;  4A3L K;  4BY7 K;  2B63 K;  4XLN A;  1WOO A;  2NVQ K;  3GTO C;  4WIL A;  4KMD A;  2ZUF A;  2CFA B;  4MQ9 A;  4M1X A;  2R92 C;  3L4K A;  4A3K K;  5HQH A;  5C44 K;  5IYB K;  3GTM C;  4GTB A;  3ADA C;  3SZY A;  3S1R C;  1J98 A;  2JA7 K;  4A3K C;  2EBB A;  3HOY C;  1WOP A;  2GAH C;  1B4A A;  2JA6 C;  2JA5 K;  5JVG S;  1Y1W A;  5TMC A;  1Y1V A;  3CQZ K;  5HL8 A;  3GTQ K;  3S16 K;  3I4N K;  4AYB L;  2YU9 K;  3Q3Q A;  4GTF A;  2WAQ D;  3RZO C;  2CW0 A;  2FQT A;  5EGE A;  1DCH A;  3S16 C;  3K7A K;  3CAG A;  3OEP A;  5M3M K;  4KM8 A;  4YFN A;  3GEH A;  3N3Y A;  4KAR A;  3GTM A;  2P5M A;  1JQW A;  1GE9 A;  2NVY K;  1IE0 A;  5IYC C;  3S1N K;  4C45 A;  5IP9 K;  1WCM K;  1XZQ B;  2V6S A;  2E2I A;  5L46 A;  1VH2 A;  3TFJ A;  3S1Q K;  3I4M K;  1HQM A;  4C3J C;  3AQP A;  3HXA A;  1ISE A;  5IYC K;  3M3Y C;  2PHC B;  3HOZ C;  5M5W K;  4C3J K;  2JH3 A;  4LK0 A;  1TWF K;  2PMZ L;  2L5N A;  3BP8 C;  4OIN A;  1KQ4 A;  1K83 C;  1XZQ A;  2E2H K;  1YNN A;  4KN7 A;  2JA6 K;  4BXX K;  1XXB A;  1SFO K;  4QIW L;  3S17 C;  2GSO A;  4Y52 C;  4Y7N C;  4X6A C;  4Q4Z A;  5C3E C;  1I50 K;  4G0V A;  1DCP A;  3FKI C;  4KC6 A;  3GTO A;  1BDF A;  4YG2 A;  1WOS A;  1WSV A;  2VUM K;  4GZY A;  5C4J K;  1XPP A;  1TWC C;  3N0B A;  2B63 A;  4AYB D;  3EQL A;  4BY7 C;  4LQY A;  3S2H C;  1WCM C;  1JVI A;  3HOX K;  1O25 A;  3GTJ A;  1EK8 A;  1EH1 A;  1O27 A;  1TWA C;  3BUE A;  2B63 C;  4KAS A;  2JA5 A;  4A3B K;  1WQF A;  1PJ5 A;  3HOW K;  2NVX C;  5CHP A;  3LAJ A;  3RZD K;  2R93 K;  3GTK A;  4WJ4 A;  3GTQ C;  3ORE A;  2YU9 A;  4C2M C;  1B4B A;  3A8I A;  5IP7 K;  4A3D C;  1J6W A;  3GIR A;  1F7U A;  5TMF A;  2WB1 D;  4GTE A;  4GTA A;  4A3J K;  3S14 K;  1O29 A;  3PO2 K;  1XZP B;  4LR2 A;  1ZBS A;  4OIP A;  2E2I C;  2E2J C;  2PA8 L;  4G0W A;  1FEU A;  5JFE A;  2KXY A;  3G4A A;  2JA8 K;  4WFB S;  3N0C A;  1Y1V C;  2JA7 A;  3S1M K;  3LAP A;  3GTP C;  5IOR A;  5JVO A;  2CFA A;  3H0G K;  2D6F C;  4BY1 K;  2NVT C;  1PJ7 A;  1Y1V K;  2A6E A;  2RH6 A;  3TFI A;  4A3G K;  4A3F C;  5IYD K;  4GTD A;  1TWG C;  1I6H K;  1XXA A;  3HOU C; 
#chains in the Genus database with same CATH homology
 4A3D K;  3HOZ C;  3S1Q C;  4A3E K;  5M5W K;  4ZH4 A;  4C3J K;  2A69 A;  5IP7 C;  2O5I A;  1TWG K;  4KN4 A;  3I4N C;  5M5Y K;  4LK0 A;  4A3G C;  3I4M C;  1TWF K;  3GTJ C;  4A3F K;  2PPB A;  3CQZ C;  4Y7N K;  3GTL K;  2PMZ L;  3HOZ K;  4OIQ A;  3GTM K;  4YFX A;  1SFO C;  4OIN A;  3HOW C;  1R9T C;  1K83 C;  2JA7 C;  3FKI K;  3M3Y K;  4XLP A;  2E2H K;  5D4D A;  1SMY A;  4BBS K;  4A3C K;  1YNN A;  4KN7 A;  2JA6 K;  4BXX K;  3PO3 K;  1SFO K;  2R93 C;  3S17 C;  2A68 A;  4JK1 A;  4QIW L;  4C2M K;  3HOY K;  2Y0S D;  4A3I K;  4Y52 C;  4Y7N C;  1TWC K;  2JA5 C;  4X6A C;  4BBS C;  3M4O C;  4A3C C;  4Q4Z A;  2JA8 C;  4BXX C;  5C3E C;  1I3Q K;  1I50 K;  1R9T K;  3FKI C;  3HOX C;  3GTP K;  1BDF A;  4YG2 A;  2YU9 C;  4BBR C;  4A3L C;  3HKZ D;  4A3M K;  3GTK C;  3HKZ L;  2VUM K;  3M4O K;  4GZY A;  1Y1W C;  4A3J C;  3S14 C;  5C4J K;  3S15 K;  4A93 K;  4G7H A;  4A3I C;  1TWC C;  1XPP A;  4Y52 K;  2NVQ C;  4AYB D;  3EQL A;  4BY7 C;  3S2H C;  1ZYR A;  3GTO K;  1WCM C;  4A3M C;  3HOX K;  5C4J C;  1I6V A;  3K7A C;  3S15 C;  3H3V D;  4Q5S A;  5C44 C;  2BE5 A;  4BBR K;  4XSX A;  4A3L K;  4BY7 K;  4LK1 A;  3S2H K;  2B63 K;  4XLN A;  1TWA C;  2NVX K;  1YNJ A;  3RZD C;  2NVQ K;  3GTO C;  2A6H A;  2O5J A;  2B63 C;  4MEY A;  4LJZ A;  4MQ9 A;  4A3K K;  2R92 C;  4QJV B;  5C44 K;  4A3B K;  5M5X K;  4BY1 C;  5IYB K;  3GTM C;  5IYD C;  3S1R C;  3HOW K;  2NVX C;  1K83 K;  4A3K C;  1TWA K;  3RZD K;  2JA7 K;  2R92 K;  2R93 K;  3HOY C;  3HOV C;  2JA6 C;  2JA5 K;  3GTQ C;  5IYB C;  4C2M C;  2PA8 D;  5IP7 K;  4A3B C;  5FLM K;  4A3D C;  5TMC A;  2E2I K;  4MEX A;  4C3I K;  3GTL C;  3GTJ K;  3S2D K;  3CQZ K;  1I3Q C;  5C3E K;  5TMF A;  4OIO A;  2WB1 D;  3GTQ K;  3S16 K;  2E2J K;  3I4N K;  4A3J K;  3S14 K;  3HOV K;  3PO2 K;  4AYB L;  2VUM C;  2YU9 K;  4OIP A;  2E2I C;  2WAQ D;  3DXJ A;  1TWH C;  3RZO C;  3S2D C;  2CW0 A;  4A93 C;  1Y1W K;  3PO3 C;  3H3V L;  3S16 C;  2E2J C;  4LLG A;  3K7A K;  2E2H C;  2PA8 L;  4C3I C;  5M3M K;  5C4X C;  4X6A K;  1TWH K;  3RZO K;  2JA8 K;  5IYC K;  2NVY C;  1I50 C;  4YFN A;  3GTG K;  3S17 K;  3PO2 C;  1Y1V C;  2Y0S L;  4KMU A;  5IP9 C;  2PMZ D;  3S1M K;  4C3H C;  2WAQ L;  2R7Z K;  5C4X K;  3GTK K;  4G7Z A;  2NVY K;  3GTP C;  4YFK A;  5IYC C;  3HOU K;  3S1N K;  3H0G K;  2WB1 L;  4BY1 K;  5IP9 K;  4QJV A;  2NVT C;  1I6H C;  2R7Z C;  1WCM K;  3WOD A;  3GTG C;  4C3H K;  5FJ8 K;  5M3F K;  1IW7 A;  4QIW D;  2A6E A;  1Y1V K;  4A3G K;  3S1Q K;  3S1M C;  1TWF C;  4A3E C;  4OIR A;  4A3F C;  4G7O A;  3I4M K;  5IYD K;  1HQM A;  4XSZ A;  4NOI A;  4C3J C;  3S1R K;  1TWG C;  2NVT K;  1I6H K;  3HOU C;  3S1N C;  3H0G C;  5FLM C;  3M3Y C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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