3CXCE

The structure of an enhanced oxazolidinone inhibitor bound to the 50s ribosomal subunit of h. marismortui
Total Genus 37
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
172
structure length
172
Chain Sequence
PRVELEIPEDVDAEQDHLDITVEGDNGSVTRRLWYPDIDVSVDGDTVVIESDEDNAKTMSTIGTFQSHIENMFHGVTEGWEYGMEVFYSHFPMQVNVEGDEVVIENFLGEKAPRRTTIHGDTDVEIDGEELTVSGPDIEAVGQTAADIEQLTRINDKDVRVFQDGVYITRKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Design at the atomic level: design of biaryloxazolidinones as potent orally active antibiotics.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S RIBOSOMAL RNA
total genus 37
structure length 172
sequence length 172
ec nomenclature
pdb deposition date 2008-04-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00347 Ribosomal_L6 Ribosomal protein L6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3cxcE02
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3cxcE01
1W2BE 1VQ5E 3CMEE 1Q82G 1YJ9E 3G4SE 1K8AG 1VQ9E 1KD1G 1K73G 5DM7E 1VQLE 2CQLA 5HL7E 1VQ4E 3PIOE 1YJWE 1Q81G 3G71E 3PIPE 3CPWE 1RL6A 4U67E 2QEXE 1YIJE 5GAEG 1YHQE 1K9MG 1YITE 3CC2E 5JVGE 4WCEE 2OTLE 3CCUE 3CC7E 1VQ8E 1M1KG 1VQOE 1KC8G 3CD6E 3CCLE 1QVGE 1VQME 2QA4E 4UY8G 5MLCH 5JVHE 5GAGG 3CCME 4WF9E 5H1SI 1JJ2E 2ZJPE 2OTJE 3CCJE 3CCRE 4IOAE 1KQSE 3J7ZG 1VQ6E 3CC4E 4WFAE 3G6EE 4IO9E 3CCSE 3DLLE 5AN9B 1VQPE 1YJNE 5GADG 1VQNE 3CCVE 4WFNE 1QVFE 3CCEE 1YI2E 4IOCE 1S72E 3CCQE 3CF5E 3OW2E 2ZJQE 3CXCE 1N8RG 3I55E 1M90G 5GAHG 1NJIG 1Q7YG 1Q86G 5DM6E 3CMAE 1VQ7E 1VQKE 4WFBE 2ZJRE 3I56E
chains in the Genus database with same CATH superfamily
1W2BE 1VQ5E 3CMEE 1Q82G 2OL6O 1YJ9E 3G4SE 1K8AG 1VQ9E 2FKJA 2G8CO 1KD1G 1K73G 5DM7E 2OL7A 1VQLE 2OYBO 2CQLA 5HL7E 1VQ4E 3PIOE 2PI3O 5B11O 1YJWE 1Q81G 3G71E 3PIPE 3CPWE 1RL6A 4U67E 2OY7A 2QEXE 1YIJE 5GAEG 1YHQE 1K9MG 1YITE 3CC2E 5JVGE 2OY5O 4WCEE 2OTLE 3CKGA 1FJ1E 3CCUE 3CC7E 5B10O 1VQ8E 1M1KG 1VQOE 1KC8G 3CD6E 3CCLE 1QVGE 3EC5A 3IG9A 5B3MO 1VQME 2QA4E 4UY8G 1OSPO 5MLCH 3IGEA 5GAGG 3CCME 5JVHE 4WF9E 5H1SI 3AUMO 1JJ2E 2OY1O 2ZJPE 2OTJE 3CCJE 3CCRE 4IOAE 1KQSE 3J7ZG 1VQ6E 2I5VO 3CC4E 4WFAE 3G6EE 4IO9E 3CCSE 3DLLE 2FKGA 5AN9B 1VQPE 5B2AO 1YJNE 5GADG 2I5ZO 1VQNE 3CCVE 4WFNE 1P4PA 1QVFE 3CCEE 1YI2E 4IOCE 1S72E 3CCQE 3CF5E 3OW2E 2ZJQE 2OL8O 3CXCE 3CKFA 2AF5A 1RJLC 2HKDA 2OY8A 1N8RG 3I55E 1M90G 5GAHG 1NJIG 1Q7YG 1Q86G 5DM6E 3CMAE 1VQ7E 1VQKE 4WFBE 2ZJRE 3I56E
chains in the Genus database with same CATH topology
1W2BE 1VQ5E 3CMEE 1Q82G 1YJ9E 3G4SE 1K8AG 1VQ9E 1KD1G 1K73G 5DM7E 1VQLE 2CQLA 5HL7E 1VQ4E 3PIOE 1YJWE 1Q81G 3G71E 3PIPE 3CPWE 1RL6A 4U67E 2QEXE 1YIJE 5GAEG 1YHQE 1K9MG 1YITE 3CC2E 5JVGE 4WCEE 2OTLE 3CCUE 3CC7E 1VQ8E 1M1KG 1VQOE 1KC8G 3CD6E 3CCLE 1QVGE 1VQME 2QA4E 4UY8G 5MLCH 5JVHE 5GAGG 3CCME 4WF9E 5H1SI 1JJ2E 2ZJPE 2OTJE 3CCJE 3CCRE 4IOAE 1KQSE 3J7ZG 1VQ6E 3CC4E 4WFAE 3G6EE 4IO9E 3CCSE 3DLLE 5AN9B 1VQPE 1YJNE 5GADG 1VQNE 3CCVE 4WFNE 1QVFE 3CCEE 1YI2E 4IOCE 1S72E 3CCQE 3CF5E 3OW2E 2ZJQE 3CXCE 1N8RG 3I55E 1M90G 5GAHG 1NJIG 1Q7YG 1Q86G 5DM6E 3CMAE 1VQ7E 1VQKE 4WFBE 2ZJRE 3I56E
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1W2B E;  1VQ5 E;  3CME E;  1Q82 G;  1YJ9 E;  3G4S E;  1K8A G;  1VQ9 E;  1KD1 G;  1K73 G;  5DM7 E;  1VQL E;  2CQL A;  5HL7 E;  1VQ4 E;  3PIO E;  1YJW E;  1Q81 G;  3G71 E;  3PIP E;  3CPW E;  1RL6 A;  4U67 E;  2QEX E;  1YIJ E;  5GAE G;  1YHQ E;  1K9M G;  1YIT E;  3CC2 E;  5JVG E;  4WCE E;  2OTL E;  3CCU E;  3CC7 E;  1VQ8 E;  1M1K G;  1VQO E;  1KC8 G;  3CD6 E;  3CCL E;  1QVG E;  1VQM E;  2QA4 E;  4UY8 G;  5MLC H;  5JVH E;  5GAG G;  3CCM E;  4WF9 E;  5H1S I;  1JJ2 E;  2ZJP E;  2OTJ E;  3CCJ E;  3CCR E;  4IOA E;  1KQS E;  3J7Z G;  1VQ6 E;  3CC4 E;  4WFA E;  3G6E E;  4IO9 E;  3CCS E;  3DLL E;  5AN9 B;  1VQP E;  1YJN E;  5GAD G;  1VQN E;  3CCV E;  4WFN E;  1QVF E;  3CCE E;  1YI2 E;  4IOC E;  1S72 E;  3CCQ E;  3CF5 E;  3OW2 E;  2ZJQ E;  3CXC E;  1N8R G;  3I55 E;  1M90 G;  5GAH G;  1NJI G;  1Q7Y G;  1Q86 G;  5DM6 E;  3CMA E;  1VQ7 E;  1VQK E;  4WFB E;  2ZJR E;  3I56 E; 
#chains in the Genus database with same CATH topology
 1W2B E;  1VQ5 E;  3CME E;  1Q82 G;  2OL6 O;  1YJ9 E;  3G4S E;  1K8A G;  1VQ9 E;  2FKJ A;  2G8C O;  1KD1 G;  1K73 G;  5DM7 E;  2OL7 A;  1VQL E;  2OYB O;  2CQL A;  5HL7 E;  1VQ4 E;  3PIO E;  2PI3 O;  5B11 O;  1YJW E;  1Q81 G;  3G71 E;  3PIP E;  3CPW E;  1RL6 A;  4U67 E;  2OY7 A;  2QEX E;  1YIJ E;  5GAE G;  1YHQ E;  1K9M G;  1YIT E;  3CC2 E;  5JVG E;  2OY5 O;  4WCE E;  2OTL E;  3CKG A;  1FJ1 E;  3CCU E;  3CC7 E;  5B10 O;  1VQ8 E;  1M1K G;  1VQO E;  1KC8 G;  3CD6 E;  3CCL E;  1QVG E;  3EC5 A;  3IG9 A;  5B3M O;  1VQM E;  2QA4 E;  4UY8 G;  1OSP O;  5MLC H;  3IGE A;  5GAG G;  3CCM E;  5JVH E;  4WF9 E;  5H1S I;  3AUM O;  1JJ2 E;  2OY1 O;  2ZJP E;  2OTJ E;  3CCJ E;  3CCR E;  4IOA E;  1KQS E;  3J7Z G;  1VQ6 E;  2I5V O;  3CC4 E;  4WFA E;  3G6E E;  4IO9 E;  3CCS E;  3DLL E;  2FKG A;  5AN9 B;  1VQP E;  5B2A O;  1YJN E;  5GAD G;  2I5Z O;  1VQN E;  3CCV E;  4WFN E;  1P4P A;  1QVF E;  3CCE E;  1YI2 E;  4IOC E;  1S72 E;  3CCQ E;  3CF5 E;  3OW2 E;  2ZJQ E;  2OL8 O;  3CXC E;  3CKF A;  2AF5 A;  1RJL C;  2HKD A;  2OY8 A;  1N8R G;  3I55 E;  1M90 G;  5GAH G;  1NJI G;  1Q7Y G;  1Q86 G;  5DM6 E;  3CMA E;  1VQ7 E;  1VQK E;  4WFB E;  2ZJR E;  3I56 E; 
#chains in the Genus database with same CATH homology
 1W2B E;  1VQ5 E;  3CME E;  1Q82 G;  1YJ9 E;  3G4S E;  1K8A G;  1VQ9 E;  1KD1 G;  1K73 G;  5DM7 E;  1VQL E;  2CQL A;  5HL7 E;  1VQ4 E;  3PIO E;  1YJW E;  1Q81 G;  3G71 E;  3PIP E;  3CPW E;  1RL6 A;  4U67 E;  2QEX E;  1YIJ E;  5GAE G;  1YHQ E;  1K9M G;  1YIT E;  3CC2 E;  5JVG E;  4WCE E;  2OTL E;  3CCU E;  3CC7 E;  1VQ8 E;  1M1K G;  1VQO E;  1KC8 G;  3CD6 E;  3CCL E;  1QVG E;  1VQM E;  2QA4 E;  4UY8 G;  5MLC H;  5JVH E;  5GAG G;  3CCM E;  4WF9 E;  5H1S I;  1JJ2 E;  2ZJP E;  2OTJ E;  3CCJ E;  3CCR E;  4IOA E;  1KQS E;  3J7Z G;  1VQ6 E;  3CC4 E;  4WFA E;  3G6E E;  4IO9 E;  3CCS E;  3DLL E;  5AN9 B;  1VQP E;  1YJN E;  5GAD G;  1VQN E;  3CCV E;  4WFN E;  1QVF E;  3CCE E;  1YI2 E;  4IOC E;  1S72 E;  3CCQ E;  3CF5 E;  3OW2 E;  2ZJQ E;  3CXC E;  1N8R G;  3I55 E;  1M90 G;  5GAH G;  1NJI G;  1Q7Y G;  1Q86 G;  5DM6 E;  3CMA E;  1VQ7 E;  1VQK E;  4WFB E;  2ZJR E;  3I56 E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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