3D2JA

Structure of berberine bridge enzyme from eschscholzia californica, tetragonal crystal form
Total Genus 165
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
165
sequence length
502
structure length
502
Chain Sequence
AGNDLLSCLTFNGVRNHTVFSADSDSDFNRFLHLSIQNPLFQNSLISKPSAIILPGSKEELSNTIRCIRKGSWTIRLRSGGHSYEGLSYTSDTPFILIDLMNLNRVSIDLESETAWVESGSTLGELYYAITESSSKLGFTAGWCPTVGTGGHISGGGFGMMSRKYGLAADNVVDAILIDANGAILDRQAMGEDVFWAIRGGGGGVWGAIYAWKIKLLPVPEKVTVFRVTKNVAIDEATSLLHKWQFVAEELEEDFTLSVLGGADEKQVWLTMLGFHFGLKTVAKSTFDLLFPELGLVEEDYLEMSWGESFAYLAGLETVSQLNNRFLKFDERAFKTKVDLTKEPLPSKAFYGLLERLSKEPNGFIALNGFGGQMSKISSDFTPFPHRSGTRLMVEYIVAWNQSEQKKKTEFLDWLEKVYEFMKPFVSKNPRLGYVNHIDLDLGGIDWGNKTVVNNAIEISRSWGESYFLSNYERLIRAKTLIDPNNVFNHPQSIPPMANFDY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords berberine bridge-forming enzyme
publication title A concerted mechanism for berberine bridge enzyme
pubmed doi rcsb
source organism Eschscholzia californica
molecule tags Oxidoreductase
total genus 165
structure length 502
sequence length 502
ec nomenclature ec 1.21.3.3: Reticuline oxidase.
pdb deposition date 2008-05-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF08031 BBE Berberine and berberine like
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 3d2jA01
3.30.465.50 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 3d2jA02
3.40.462.20 Alpha Beta 3-Layer(aba) Sandwich Vanillyl-alcohol Oxidase; Chain A, domain 3 Vanillyl-alcohol Oxidase; Chain A, domain 3 3d2jA03
3W8XA 2W3SA 1AHVA 5FXEA 2GQUA 1VAOA 1UXYA 5L6GA 4BCAA 1N63C 3C0PA 3W8WA 1W1KA 1HSKA 3FW7A 4PVEA 5AE3A 5L6FA 1E0YA 3BW7A 3D2DA 5HHZA 1W1QA 2W54A 4MLAA 3SR6B 5AE1A 2VFSA 2AXRA 2Y08A 1T3QC 1ZR6A 2GQTA 2W55A 2VAOA 4PVHA 3PM9A 1W1SA 5AE2A 5K8EA 1W1RA 2EXRA 1MBTA 3S1EA 4PWBA 3TX1A 4ML8A 1N60C 3I99A 3W8ZA 3FWAA 1VDVA 5FXPA 3JS8A 4O95A 3PQBA 5FXDA 4PWCA 4EC3A 2Q85A 4ZOHB 4PYTA 3VTEA 3TSHA 1N5XA 2Y4GA 1MBBA 1ZXIC 1N5WC 1W1JA 3EUB3 4BC7A 1FFUC 1WVFA 3ETRB 1I19A 1AHUA 2IPIA 1QLUA 2E3TA 3D2JA 3AM9A 5I1VA 1W1OA 2VFRA 1AHZA 3TSJA 4UD8A 4PZFA 4OALA 3S1CA 5FXFA 1V97A 5HMRA 1E8HA 1N62C 2VFVA 3HSUA 1WYGA 3KJMA 3NS1B 3AMZA 2MBRA 3GSYA 1DIQA 1E8GA 1N61C 3AN1A 3D2HA 1FO4A 5AWVA 3B9JB 3RJAA 3NVZB 2BVFA 1DIIA 3S1DA 3DQ0A 1JROA 4XLOA 2WDWA 1FFVC 2VFUA 2Q4WA 2I0KA 4PVKA 1WVEA 2VFTA 4JB1A 1E8FA 4BBYA 5D79A 4JAYA 2W3RA 4DNSA 4PVJA 1FIQB 2Y3RA 3RJ8A 1DZNA 1QLTA 2QPMA 2BVHA 2QKNA 4BC9A 5ADZA 5I1WA 3S1FA 1W1LA 3POPA 3NRZB 1W1MA 2BVGA 3FW8A 2Y3SA 3FW9A 5HQXA 1F0XA
chains in the Genus database with same CATH superfamily
3W8XA 2W3SA 1AHVA 5FXEA 2P4PA 2GQUA 1VAOA 1RM6B 1UXYA 5L6GA 4BCAA 1N63C 3C0PA 3W8WA 1W1KA 1HSKA 3FW7A 4PVEA 5AE3A 5L6FA 1E0YA 3BW7A 3D2DA 3HRDC 5HHZA 1W1QA 2W54A 4MLAA 3SR6B 5AE1A 2VFSA 2AXRA 2Y08A 1T3QC 1ZR6A 2GQTA 3NVVB 2RK5A 2W55A 2VAOA 4PVHA 3PM9A 2R2ZA 1W1SA 5AE2A 3NVWB 1W1RA 5K8EA 2EXRA 1MBTA 3S1EA 4PWBA 3TX1A 2UUUA 4ML8A 1N60C 3I99A 3W8ZA 3FWAA 1VDVA 5FXPA 3JS8A 4O95A 3EJEB 3PQBA 5FXDA 4PWCA 4EC3A 2Q85A 2YVSA 4ZOHB 4PYTA 3VTEA 2O3GA 3LAEA 3TSHA 3EJDB 1N5XA 2Y4GA 1MBBA 1ZXIC 1N5WC 1W1JA 3EUB3 4BC7A 1FFUC 1WVFA 1JRPA 3ETRB 1I19A 3LLBA 1AHUA 2IPIA 1QLUA 2E3TA 3D2JA 3AM9A 5I1VA 1W1OA 2VFRA 1AHZA 3TSJA 4UD8A 4PZFA 3DEDA 4OALA 3S1CA 5FXFA 1V97A 3NVYB 5HMRA 1E8HA 1N62C 2VFVA 3HSUA 1WYGA 3KJMA 3NS1B 3AMZA 2MBRA 3GSYA 2P13A 1DIQA 1E8GA 1N61C 3AN1A 3D2HA 1FO4A 5AWVA 3B9JB 3RJAA 3NVZB 2BVFA 2PLIA 1DIIA 3S1DA 3DQ0A 1JROA 4XLOA 2WDWA 1FFVC 2VFUA 2Q4WA 2I0KA 4PVKA 1WVEA 2VFTA 4JB1A 2P3HA 4HG0A 2R8DA 3EJBB 1E8FA 4BBYA 5D79A 4JAYA 2W3RA 4DNSA 4PVJA 1FIQB 2Y3RA 3RJ8A 5G5HB 1DZNA 1QLTA 1SB3B 2QPMA 2BVHA 2QKNA 4BC9A 5ADZA 5I1WA 3S1FA 1W1LA 5G5GB 2NQWA 3POPA 3NRZB 1W1MA 2BVGA 2OAIA 2UUVA 3FW8A 2PLSA 2Y3SA 3FW9A 5HQXA 1F0XA
chains in the Genus database with same CATH topology
3W8XA 2W3SA 1AHVA 5FXEA 2P4PA 2GQUA 1VAOA 1RM6B 1UXYA 5L6GA 4BCAA 1N63C 3C0PA 3W8WA 1W1KA 1HSKA 3FW7A 4PVEA 5AE3A 5L6FA 1E0YA 3BW7A 3D2DA 3HRDC 5HHZA 1W1QA 2W54A 4MLAA 3SR6B 5AE1A 2VFSA 2AXRA 2Y08A 1T3QC 1ZR6A 2GQTA 3NVVB 2RK5A 2W55A 2VAOA 4PVHA 3PM9A 2R2ZA 1W1SA 5AE2A 3NVWB 1W1RA 5K8EA 2EXRA 1MBTA 3S1EA 4PWBA 3TX1A 2UUUA 4ML8A 1N60C 3I99A 3W8ZA 3FWAA 1VDVA 5FXPA 3JS8A 4O95A 3PQBA 5FXDA 4PWCA 4EC3A 2Q85A 2YVSA 4ZOHB 4PYTA 3VTEA 2O3GA 3LAEA 3TSHA 1N5XA 2Y4GA 1MBBA 1ZXIC 1N5WC 1W1JA 3EUB3 4BC7A 1FFUC 1WVFA 1JRPA 3ETRB 1I19A 3LLBA 1AHUA 2IPIA 1QLUA 2E3TA 3D2JA 3AM9A 5I1VA 1W1OA 2VFRA 1AHZA 3TSJA 4UD8A 4PZFA 3DEDA 4OALA 3S1CA 5FXFA 1V97A 3NVYB 5HMRA 1E8HA 1N62C 2VFVA 3HSUA 1WYGA 3KJMA 3NS1B 3AMZA 2MBRA 3GSYA 2P13A 1DIQA 1E8GA 1N61C 3AN1A 3D2HA 1FO4A 5AWVA 3B9JB 3RJAA 3NVZB 2BVFA 2PLIA 1DIIA 3S1DA 3DQ0A 1JROA 4XLOA 2WDWA 1FFVC 2VFUA 2Q4WA 2I0KA 4PVKA 1WVEA 2VFTA 4JB1A 2P3HA 4HG0A 2R8DA 1E8FA 4BBYA 5D79A 4JAYA 2W3RA 4DNSA 4PVJA 1FIQB 2Y3RA 3RJ8A 5G5HB 1DZNA 1QLTA 1SB3B 2QPMA 2BVHA 2QKNA 4BC9A 5ADZA 5I1WA 3S1FA 1W1LA 5G5GB 2NQWA 3POPA 3NRZB 1W1MA 2BVGA 2OAIA 2UUVA 3FW8A 2PLSA 2Y3SA 3FW9A 5HQXA 1F0XA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3W8X A;  2W3S A;  1AHV A;  5FXE A;  2GQU A;  1VAO A;  1UXY A;  5L6G A;  4BCA A;  1N63 C;  3C0P A;  3W8W A;  1W1K A;  1HSK A;  3FW7 A;  4PVE A;  5AE3 A;  5L6F A;  1E0Y A;  3BW7 A;  3D2D A;  5HHZ A;  1W1Q A;  2W54 A;  4MLA A;  3SR6 B;  5AE1 A;  2VFS A;  2AXR A;  2Y08 A;  1T3Q C;  1ZR6 A;  2GQT A;  2W55 A;  2VAO A;  4PVH A;  3PM9 A;  1W1S A;  5AE2 A;  5K8E A;  1W1R A;  2EXR A;  1MBT A;  3S1E A;  4PWB A;  3TX1 A;  4ML8 A;  1N60 C;  3I99 A;  3W8Z A;  3FWA A;  1VDV A;  5FXP A;  3JS8 A;  4O95 A;  3PQB A;  5FXD A;  4PWC A;  4EC3 A;  2Q85 A;  4ZOH B;  4PYT A;  3VTE A;  3TSH A;  1N5X A;  2Y4G A;  1MBB A;  1ZXI C;  1N5W C;  1W1J A;  3EUB 3;  4BC7 A;  1FFU C;  1WVF A;  3ETR B;  1I19 A;  1AHU A;  2IPI A;  1QLU A;  2E3T A;  3D2J A;  3AM9 A;  5I1V A;  1W1O A;  2VFR A;  1AHZ A;  3TSJ A;  4UD8 A;  4PZF A;  4OAL A;  3S1C A;  5FXF A;  1V97 A;  5HMR A;  1E8H A;  1N62 C;  2VFV A;  3HSU A;  1WYG A;  3KJM A;  3NS1 B;  3AMZ A;  2MBR A;  3GSY A;  1DIQ A;  1E8G A;  1N61 C;  3AN1 A;  3D2H A;  1FO4 A;  5AWV A;  3B9J B;  3RJA A;  3NVZ B;  2BVF A;  1DII A;  3S1D A;  3DQ0 A;  1JRO A;  4XLO A;  2WDW A;  1FFV C;  2VFU A;  2Q4W A;  2I0K A;  4PVK A;  1WVE A;  2VFT A;  4JB1 A;  1E8F A;  4BBY A;  5D79 A;  4JAY A;  2W3R A;  4DNS A;  4PVJ A;  1FIQ B;  2Y3R A;  3RJ8 A;  1DZN A;  1QLT A;  2QPM A;  2BVH A;  2QKN A;  4BC9 A;  5ADZ A;  5I1W A;  3S1F A;  1W1L A;  3POP A;  3NRZ B;  1W1M A;  2BVG A;  3FW8 A;  2Y3S A;  3FW9 A;  5HQX A;  1F0X A; 
#chains in the Genus database with same CATH topology
 3W8X A;  2W3S A;  1AHV A;  5FXE A;  2P4P A;  2GQU A;  1VAO A;  1RM6 B;  1UXY A;  5L6G A;  4BCA A;  1N63 C;  3C0P A;  3W8W A;  1W1K A;  1HSK A;  3FW7 A;  4PVE A;  5AE3 A;  5L6F A;  1E0Y A;  3BW7 A;  3D2D A;  3HRD C;  5HHZ A;  1W1Q A;  2W54 A;  4MLA A;  3SR6 B;  5AE1 A;  2VFS A;  2AXR A;  2Y08 A;  1T3Q C;  1ZR6 A;  2GQT A;  3NVV B;  2RK5 A;  2W55 A;  2VAO A;  4PVH A;  3PM9 A;  2R2Z A;  1W1S A;  5AE2 A;  3NVW B;  1W1R A;  5K8E A;  2EXR A;  1MBT A;  3S1E A;  4PWB A;  3TX1 A;  2UUU A;  4ML8 A;  1N60 C;  3I99 A;  3W8Z A;  3FWA A;  1VDV A;  5FXP A;  3JS8 A;  4O95 A;  3EJE B;  3PQB A;  5FXD A;  4PWC A;  4EC3 A;  2Q85 A;  2YVS A;  4ZOH B;  4PYT A;  3VTE A;  2O3G A;  3LAE A;  3TSH A;  3EJD B;  1N5X A;  2Y4G A;  1MBB A;  1ZXI C;  1N5W C;  1W1J A;  3EUB 3;  4BC7 A;  1FFU C;  1WVF A;  1JRP A;  3ETR B;  1I19 A;  3LLB A;  1AHU A;  2IPI A;  1QLU A;  2E3T A;  3D2J A;  3AM9 A;  5I1V A;  1W1O A;  2VFR A;  1AHZ A;  3TSJ A;  4UD8 A;  4PZF A;  3DED A;  4OAL A;  3S1C A;  5FXF A;  1V97 A;  3NVY B;  5HMR A;  1E8H A;  1N62 C;  2VFV A;  3HSU A;  1WYG A;  3KJM A;  3NS1 B;  3AMZ A;  2MBR A;  3GSY A;  2P13 A;  1DIQ A;  1E8G A;  1N61 C;  3AN1 A;  3D2H A;  1FO4 A;  5AWV A;  3B9J B;  3RJA A;  3NVZ B;  2BVF A;  2PLI A;  1DII A;  3S1D A;  3DQ0 A;  1JRO A;  4XLO A;  2WDW A;  1FFV C;  2VFU A;  2Q4W A;  2I0K A;  4PVK A;  1WVE A;  2VFT A;  4JB1 A;  2P3H A;  4HG0 A;  2R8D A;  3EJB B;  1E8F A;  4BBY A;  5D79 A;  4JAY A;  2W3R A;  4DNS A;  4PVJ A;  1FIQ B;  2Y3R A;  3RJ8 A;  5G5H B;  1DZN A;  1QLT A;  1SB3 B;  2QPM A;  2BVH A;  2QKN A;  4BC9 A;  5ADZ A;  5I1W A;  3S1F A;  1W1L A;  5G5G B;  2NQW A;  3POP A;  3NRZ B;  1W1M A;  2BVG A;  2OAI A;  2UUV A;  3FW8 A;  2PLS A;  2Y3S A;  3FW9 A;  5HQX A;  1F0X A; 
#chains in the Genus database with same CATH homology
 3W8X A;  2W3S A;  1AHV A;  5FXE A;  2P4P A;  2GQU A;  1VAO A;  1RM6 B;  1UXY A;  5L6G A;  4BCA A;  1N63 C;  3C0P A;  3W8W A;  1W1K A;  1HSK A;  3FW7 A;  4PVE A;  5AE3 A;  5L6F A;  1E0Y A;  3BW7 A;  3D2D A;  3HRD C;  5HHZ A;  1W1Q A;  2W54 A;  4MLA A;  3SR6 B;  5AE1 A;  2VFS A;  2AXR A;  2Y08 A;  1T3Q C;  1ZR6 A;  2GQT A;  3NVV B;  2RK5 A;  2W55 A;  2VAO A;  4PVH A;  3PM9 A;  2R2Z A;  1W1S A;  5AE2 A;  3NVW B;  1W1R A;  5K8E A;  2EXR A;  1MBT A;  3S1E A;  4PWB A;  3TX1 A;  2UUU A;  4ML8 A;  1N60 C;  3I99 A;  3W8Z A;  3FWA A;  1VDV A;  5FXP A;  3JS8 A;  4O95 A;  3PQB A;  5FXD A;  4PWC A;  4EC3 A;  2Q85 A;  2YVS A;  4ZOH B;  4PYT A;  3VTE A;  2O3G A;  3LAE A;  3TSH A;  1N5X A;  2Y4G A;  1MBB A;  1ZXI C;  1N5W C;  1W1J A;  3EUB 3;  4BC7 A;  1FFU C;  1WVF A;  1JRP A;  3ETR B;  1I19 A;  3LLB A;  1AHU A;  2IPI A;  1QLU A;  2E3T A;  3D2J A;  3AM9 A;  5I1V A;  1W1O A;  2VFR A;  1AHZ A;  3TSJ A;  4UD8 A;  4PZF A;  3DED A;  4OAL A;  3S1C A;  5FXF A;  1V97 A;  3NVY B;  5HMR A;  1E8H A;  1N62 C;  2VFV A;  3HSU A;  1WYG A;  3KJM A;  3NS1 B;  3AMZ A;  2MBR A;  3GSY A;  2P13 A;  1DIQ A;  1E8G A;  1N61 C;  3AN1 A;  3D2H A;  1FO4 A;  5AWV A;  3B9J B;  3RJA A;  3NVZ B;  2BVF A;  2PLI A;  1DII A;  3S1D A;  3DQ0 A;  1JRO A;  4XLO A;  2WDW A;  1FFV C;  2VFU A;  2Q4W A;  2I0K A;  4PVK A;  1WVE A;  2VFT A;  4JB1 A;  2P3H A;  4HG0 A;  2R8D A;  1E8F A;  4BBY A;  5D79 A;  4JAY A;  2W3R A;  4DNS A;  4PVJ A;  1FIQ B;  2Y3R A;  3RJ8 A;  5G5H B;  1DZN A;  1QLT A;  1SB3 B;  2QPM A;  2BVH A;  2QKN A;  4BC9 A;  5ADZ A;  5I1W A;  3S1F A;  1W1L A;  5G5G B;  2NQW A;  3POP A;  3NRZ B;  1W1M A;  2BVG A;  2OAI A;  2UUV A;  3FW8 A;  2PLS A;  2Y3S A;  3FW9 A;  5HQX A;  1F0X A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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