3D2JA

Structure of berberine bridge enzyme from eschscholzia californica, tetragonal crystal form
Total Genus 165
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
165
sequence length
502
structure length
502
Chain Sequence
AGNDLLSCLTFNGVRNHTVFSADSDSDFNRFLHLSIQNPLFQNSLISKPSAIILPGSKEELSNTIRCIRKGSWTIRLRSGGHSYEGLSYTSDTPFILIDLMNLNRVSIDLESETAWVESGSTLGELYYAITESSSKLGFTAGWCPTVGTGGHISGGGFGMMSRKYGLAADNVVDAILIDANGAILDRQAMGEDVFWAIRGGGGGVWGAIYAWKIKLLPVPEKVTVFRVTKNVAIDEATSLLHKWQFVAEELEEDFTLSVLGGADEKQVWLTMLGFHFGLKTVAKSTFDLLFPELGLVEEDYLEMSWGESFAYLAGLETVSQLNNRFLKFDERAFKTKVDLTKEPLPSKAFYGLLERLSKEPNGFIALNGFGGQMSKISSDFTPFPHRSGTRLMVEYIVAWNQSEQKKKTEFLDWLEKVYEFMKPFVSKNPRLGYVNHIDLDLGGIDWGNKTVVNNAIEISRSWGESYFLSNYERLIRAKTLIDPNNVFNHPQSIPPMANFDY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords berberine bridge-forming enzyme
publication title A concerted mechanism for berberine bridge enzyme
pubmed doi rcsb
source organism Eschscholzia californica
molecule tags Oxidoreductase
total genus 165
structure length 502
sequence length 502
ec nomenclature ec 1.21.3.3: Reticuline oxidase.
pdb deposition date 2008-05-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF08031 BBE Berberine and berberine like
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 3d2jA01
3.30.465.50 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 3d2jA02
3.40.462.20 Alpha Beta 3-Layer(aba) Sandwich Vanillyl-alcohol Oxidase; Chain A, domain 3 Vanillyl-alcohol Oxidase; Chain A, domain 3 3d2jA03
1N5WC 3RJ8A 2Y08A 2BVHA 1FFUC 1QLTA 5HHZA 1W1OA 2VFSA 2Q4WA 3GSYA 2QPMA 3FWAA 3I99A 5HQXA 3DQ0A 3FW8A 4O95A 3D2DA 3JS8A 4PZFA 1E0YA 1N62C 1ZXIC 2WDWA 2AXRA 2VFTA 1WVEA 1FIQB 1DIIA 1HSKA 1W1RA 2VAOA 3RJAA 1QLUA 1MBBA 5D79A 3VTEA 5AE1A 4ML8A 3NRZB 1UXYA 1AHVA 1V97A 2E3TA 5HMRA 1N5XA 4PVEA 2VFUA 4UD8A 1F0XA 4ZOHB 5L6GA 2BVFA 3W8ZA 3NVZB 4OALA 3NS1B 5K8EA 1AHZA 1I19A 3TX1A 1FO4A 1WVFA 1E8HA 3TSHA 3SR6B 4JB1A 4PWBA 3W8WA 1ZR6A 1MBTA 1W1MA 3C0PA 4XLOA 1FFVC 3S1FA 4JAYA 3AN1A 2EXRA 2IPIA 4MLAA 2BVGA 2VFRA 3FW7A 1JROA 5FXEA 2Y3SA 1T3QC 5L6FA 2VFVA 3POPA 4PWCA 5I1WA 5FXDA 1W1JA 4BBYA 5FXPA 3HSUA 3S1DA 4DNSA 4PVKA 3TSJA 2W55A 3D2JA 1N63C 2Q85A 1E8FA 3PQBA 4BCAA 1W1SA 2GQUA 5AE2A 1DZNA 1W1QA 2W3SA 3W8XA 1VDVA 5AWVA 1N61C 2W54A 2Y3RA 3ETRB 2Y4GA 5FXFA 4EC3A 5ADZA 3FW9A 2QKNA 4BC7A 3EUB3 1W1LA 3PM9A 3AMZA 5AE3A 4BC9A 5I1VA 1E8GA 2MBRA 4PVHA 3D2HA 2I0KA 2GQTA 1DIQA 3AM9A 3S1CA 1WYGA 2W3RA 3KJMA 1VAOA 1W1KA 1N60C 4PYTA 3S1EA 1AHUA 4PVJA 3BW7A 3B9JB
chains in the Genus database with same CATH superfamily
1N5WC 3RJ8A 3EJBB 2Y08A 2BVHA 1FFUC 1QLTA 5HHZA 2NQWA 3DEDA 1W1OA 2VFSA 2Q4WA 3GSYA 2QPMA 3FWAA 3I99A 5HQXA 1RM6B 3DQ0A 3FW8A 4O95A 3D2DA 3JS8A 4PZFA 1E0YA 1N62C 1ZXIC 2WDWA 2P13A 2AXRA 2VFTA 3LAEA 1WVEA 1FIQB 1DIIA 1HSKA 1W1RA 2VAOA 3LLBA 3NVWB 3RJAA 1QLUA 1MBBA 5D79A 3VTEA 5AE1A 4ML8A 2UUUA 3NRZB 1UXYA 1AHVA 1V97A 2E3TA 5HMRA 1N5XA 4PVEA 2VFUA 4UD8A 1F0XA 4ZOHB 5L6GA 2P3HA 2BVFA 3EJEB 3W8ZA 3NVZB 4OALA 3NS1B 5K8EA 1AHZA 1I19A 3TX1A 1FO4A 1WVFA 1E8HA 2RK5A 3TSHA 3SR6B 1JRPA 4JB1A 4PWBA 3W8WA 1ZR6A 1MBTA 1W1MA 3C0PA 4XLOA 1FFVC 3S1FA 4JAYA 3AN1A 2EXRA 2IPIA 4MLAA 2BVGA 2VFRA 3FW7A 2O3GA 1SB3B 2P4PA 1JROA 5FXEA 2Y3SA 1T3QC 5L6FA 2VFVA 3POPA 5G5HB 4PWCA 5G5GB 2PLSA 5I1WA 5FXDA 1W1JA 4BBYA 5FXPA 3HSUA 3S1DA 4DNSA 4PVKA 2YVSA 3TSJA 2W55A 3D2JA 1N63C 2PLIA 2Q85A 1E8FA 3PQBA 4BCAA 1W1SA 2GQUA 5AE2A 1DZNA 1W1QA 2W3SA 3W8XA 1VDVA 5AWVA 1N61C 2W54A 2Y3RA 3ETRB 2Y4GA 2OAIA 4HG0A 5FXFA 3NVVB 4EC3A 5ADZA 3FW9A 2QKNA 4BC7A 3EJDB 3EUB3 1W1LA 3PM9A 3AMZA 5AE3A 4BC9A 5I1VA 2UUVA 1E8GA 2MBRA 4PVHA 3D2HA 2R8DA 2I0KA 3HRDC 2GQTA 1DIQA 3AM9A 3S1CA 1WYGA 2W3RA 3KJMA 2R2ZA 1VAOA 1W1KA 1N60C 4PYTA 3S1EA 1AHUA 4PVJA 3NVYB 3BW7A 3B9JB
chains in the Genus database with same CATH topology
1N5WC 3RJ8A 2Y08A 2BVHA 1FFUC 1QLTA 5HHZA 2NQWA 3DEDA 1W1OA 2VFSA 2Q4WA 3GSYA 2QPMA 3FWAA 3I99A 5HQXA 1RM6B 3DQ0A 3FW8A 4O95A 3D2DA 3JS8A 4PZFA 1E0YA 1N62C 1ZXIC 2WDWA 2P13A 2AXRA 2VFTA 3LAEA 1WVEA 1FIQB 1DIIA 1HSKA 1W1RA 2VAOA 3LLBA 3NVWB 3RJAA 1QLUA 1MBBA 5D79A 3VTEA 5AE1A 4ML8A 2UUUA 3NRZB 1UXYA 1AHVA 1V97A 2E3TA 5HMRA 1N5XA 4PVEA 2VFUA 4UD8A 1F0XA 4ZOHB 5L6GA 2P3HA 2BVFA 3W8ZA 3NVZB 4OALA 3NS1B 5K8EA 1AHZA 1I19A 3TX1A 1FO4A 1WVFA 1E8HA 2RK5A 3TSHA 3SR6B 1JRPA 4JB1A 4PWBA 3W8WA 1ZR6A 1MBTA 1W1MA 3C0PA 4XLOA 1FFVC 3S1FA 4JAYA 3AN1A 2EXRA 2IPIA 4MLAA 2BVGA 2VFRA 3FW7A 2O3GA 1SB3B 2P4PA 1JROA 5FXEA 2Y3SA 1T3QC 5L6FA 2VFVA 3POPA 5G5HB 4PWCA 5G5GB 2PLSA 5I1WA 5FXDA 1W1JA 4BBYA 5FXPA 3HSUA 3S1DA 4DNSA 4PVKA 2YVSA 3TSJA 2W55A 3D2JA 1N63C 2PLIA 2Q85A 1E8FA 3PQBA 4BCAA 1W1SA 2GQUA 5AE2A 1DZNA 1W1QA 2W3SA 3W8XA 1VDVA 5AWVA 1N61C 2W54A 2Y3RA 3ETRB 2Y4GA 2OAIA 4HG0A 5FXFA 4EC3A 3NVVB 5ADZA 3FW9A 2QKNA 4BC7A 3EUB3 1W1LA 3PM9A 3AMZA 5AE3A 4BC9A 5I1VA 2UUVA 1E8GA 2MBRA 4PVHA 3D2HA 2R8DA 2I0KA 3HRDC 2GQTA 1DIQA 3AM9A 3S1CA 1WYGA 2W3RA 3KJMA 2R2ZA 1VAOA 1W1KA 1N60C 4PYTA 3S1EA 1AHUA 4PVJA 3NVYB 3BW7A 3B9JB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1N5W C;  3RJ8 A;  2Y08 A;  2BVH A;  1FFU C;  1QLT A;  5HHZ A;  1W1O A;  2VFS A;  2Q4W A;  3GSY A;  2QPM A;  3FWA A;  3I99 A;  5HQX A;  3DQ0 A;  3FW8 A;  4O95 A;  3D2D A;  3JS8 A;  4PZF A;  1E0Y A;  1N62 C;  1ZXI C;  2WDW A;  2AXR A;  2VFT A;  1WVE A;  1FIQ B;  1DII A;  1HSK A;  1W1R A;  2VAO A;  3RJA A;  1QLU A;  1MBB A;  5D79 A;  3VTE A;  5AE1 A;  4ML8 A;  3NRZ B;  1UXY A;  1AHV A;  1V97 A;  2E3T A;  5HMR A;  1N5X A;  4PVE A;  2VFU A;  4UD8 A;  1F0X A;  4ZOH B;  5L6G A;  2BVF A;  3W8Z A;  3NVZ B;  4OAL A;  3NS1 B;  5K8E A;  1AHZ A;  1I19 A;  3TX1 A;  1FO4 A;  1WVF A;  1E8H A;  3TSH A;  3SR6 B;  4JB1 A;  4PWB A;  3W8W A;  1ZR6 A;  1MBT A;  1W1M A;  3C0P A;  4XLO A;  1FFV C;  3S1F A;  4JAY A;  3AN1 A;  2EXR A;  2IPI A;  4MLA A;  2BVG A;  2VFR A;  3FW7 A;  1JRO A;  5FXE A;  2Y3S A;  1T3Q C;  5L6F A;  2VFV A;  3POP A;  4PWC A;  5I1W A;  5FXD A;  1W1J A;  4BBY A;  5FXP A;  3HSU A;  3S1D A;  4DNS A;  4PVK A;  3TSJ A;  2W55 A;  3D2J A;  1N63 C;  2Q85 A;  1E8F A;  3PQB A;  4BCA A;  1W1S A;  2GQU A;  5AE2 A;  1DZN A;  1W1Q A;  2W3S A;  3W8X A;  1VDV A;  5AWV A;  1N61 C;  2W54 A;  2Y3R A;  3ETR B;  2Y4G A;  5FXF A;  4EC3 A;  5ADZ A;  3FW9 A;  2QKN A;  4BC7 A;  3EUB 3;  1W1L A;  3PM9 A;  3AMZ A;  5AE3 A;  4BC9 A;  5I1V A;  1E8G A;  2MBR A;  4PVH A;  3D2H A;  2I0K A;  2GQT A;  1DIQ A;  3AM9 A;  3S1C A;  1WYG A;  2W3R A;  3KJM A;  1VAO A;  1W1K A;  1N60 C;  4PYT A;  3S1E A;  1AHU A;  4PVJ A;  3BW7 A;  3B9J B; 
#chains in the Genus database with same CATH topology
 1N5W C;  3RJ8 A;  3EJB B;  2Y08 A;  2BVH A;  1FFU C;  1QLT A;  5HHZ A;  2NQW A;  3DED A;  1W1O A;  2VFS A;  2Q4W A;  3GSY A;  2QPM A;  3FWA A;  3I99 A;  5HQX A;  1RM6 B;  3DQ0 A;  3FW8 A;  4O95 A;  3D2D A;  3JS8 A;  4PZF A;  1E0Y A;  1N62 C;  1ZXI C;  2WDW A;  2P13 A;  2AXR A;  2VFT A;  3LAE A;  1WVE A;  1FIQ B;  1DII A;  1HSK A;  1W1R A;  2VAO A;  3LLB A;  3NVW B;  3RJA A;  1QLU A;  1MBB A;  5D79 A;  3VTE A;  5AE1 A;  4ML8 A;  2UUU A;  3NRZ B;  1UXY A;  1AHV A;  1V97 A;  2E3T A;  5HMR A;  1N5X A;  4PVE A;  2VFU A;  4UD8 A;  1F0X A;  4ZOH B;  5L6G A;  2P3H A;  2BVF A;  3EJE B;  3W8Z A;  3NVZ B;  4OAL A;  3NS1 B;  5K8E A;  1AHZ A;  1I19 A;  3TX1 A;  1FO4 A;  1WVF A;  1E8H A;  2RK5 A;  3TSH A;  3SR6 B;  1JRP A;  4JB1 A;  4PWB A;  3W8W A;  1ZR6 A;  1MBT A;  1W1M A;  3C0P A;  4XLO A;  1FFV C;  3S1F A;  4JAY A;  3AN1 A;  2EXR A;  2IPI A;  4MLA A;  2BVG A;  2VFR A;  3FW7 A;  2O3G A;  1SB3 B;  2P4P A;  1JRO A;  5FXE A;  2Y3S A;  1T3Q C;  5L6F A;  2VFV A;  3POP A;  5G5H B;  4PWC A;  5G5G B;  2PLS A;  5I1W A;  5FXD A;  1W1J A;  4BBY A;  5FXP A;  3HSU A;  3S1D A;  4DNS A;  4PVK A;  2YVS A;  3TSJ A;  2W55 A;  3D2J A;  1N63 C;  2PLI A;  2Q85 A;  1E8F A;  3PQB A;  4BCA A;  1W1S A;  2GQU A;  5AE2 A;  1DZN A;  1W1Q A;  2W3S A;  3W8X A;  1VDV A;  5AWV A;  1N61 C;  2W54 A;  2Y3R A;  3ETR B;  2Y4G A;  2OAI A;  4HG0 A;  5FXF A;  3NVV B;  4EC3 A;  5ADZ A;  3FW9 A;  2QKN A;  4BC7 A;  3EJD B;  3EUB 3;  1W1L A;  3PM9 A;  3AMZ A;  5AE3 A;  4BC9 A;  5I1V A;  2UUV A;  1E8G A;  2MBR A;  4PVH A;  3D2H A;  2R8D A;  2I0K A;  3HRD C;  2GQT A;  1DIQ A;  3AM9 A;  3S1C A;  1WYG A;  2W3R A;  3KJM A;  2R2Z A;  1VAO A;  1W1K A;  1N60 C;  4PYT A;  3S1E A;  1AHU A;  4PVJ A;  3NVY B;  3BW7 A;  3B9J B; 
#chains in the Genus database with same CATH homology
 1N5W C;  3RJ8 A;  2Y08 A;  2BVH A;  1FFU C;  1QLT A;  5HHZ A;  2NQW A;  3DED A;  1W1O A;  2VFS A;  2Q4W A;  3GSY A;  2QPM A;  3FWA A;  3I99 A;  5HQX A;  1RM6 B;  3DQ0 A;  3FW8 A;  4O95 A;  3D2D A;  3JS8 A;  4PZF A;  1E0Y A;  1N62 C;  1ZXI C;  2WDW A;  2P13 A;  2AXR A;  2VFT A;  3LAE A;  1WVE A;  1FIQ B;  1DII A;  1HSK A;  1W1R A;  2VAO A;  3LLB A;  3NVW B;  3RJA A;  1QLU A;  1MBB A;  5D79 A;  3VTE A;  5AE1 A;  4ML8 A;  2UUU A;  3NRZ B;  1UXY A;  1AHV A;  1V97 A;  2E3T A;  5HMR A;  1N5X A;  4PVE A;  2VFU A;  4UD8 A;  1F0X A;  4ZOH B;  5L6G A;  2P3H A;  2BVF A;  3W8Z A;  3NVZ B;  4OAL A;  3NS1 B;  5K8E A;  1AHZ A;  1I19 A;  3TX1 A;  1FO4 A;  1WVF A;  1E8H A;  2RK5 A;  3TSH A;  3SR6 B;  1JRP A;  4JB1 A;  4PWB A;  3W8W A;  1ZR6 A;  1MBT A;  1W1M A;  3C0P A;  4XLO A;  1FFV C;  3S1F A;  4JAY A;  3AN1 A;  2EXR A;  2IPI A;  4MLA A;  2BVG A;  2VFR A;  3FW7 A;  2O3G A;  1SB3 B;  2P4P A;  1JRO A;  5FXE A;  2Y3S A;  1T3Q C;  5L6F A;  2VFV A;  3POP A;  5G5H B;  4PWC A;  5G5G B;  2PLS A;  5I1W A;  5FXD A;  1W1J A;  4BBY A;  5FXP A;  3HSU A;  3S1D A;  4DNS A;  4PVK A;  2YVS A;  3TSJ A;  2W55 A;  3D2J A;  1N63 C;  2PLI A;  2Q85 A;  1E8F A;  3PQB A;  4BCA A;  1W1S A;  2GQU A;  5AE2 A;  1DZN A;  1W1Q A;  2W3S A;  3W8X A;  1VDV A;  5AWV A;  1N61 C;  2W54 A;  2Y3R A;  3ETR B;  2Y4G A;  2OAI A;  4HG0 A;  5FXF A;  4EC3 A;  3NVV B;  5ADZ A;  3FW9 A;  2QKN A;  4BC7 A;  3EUB 3;  1W1L A;  3PM9 A;  3AMZ A;  5AE3 A;  4BC9 A;  5I1V A;  2UUV A;  1E8G A;  2MBR A;  4PVH A;  3D2H A;  2R8D A;  2I0K A;  3HRD C;  2GQT A;  1DIQ A;  3AM9 A;  3S1C A;  1WYG A;  2W3R A;  3KJM A;  2R2Z A;  1VAO A;  1W1K A;  1N60 C;  4PYT A;  3S1E A;  1AHU A;  4PVJ A;  3NVY B;  3BW7 A;  3B9J B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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