3DPQA

Crystal structure of the substrate binding domain of e. coli dnak in complex with a long pyrrhocoricin-derived inhibitor peptide (form b)
Total Genus 52
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
52
sequence length
212
structure length
212
Chain Sequence
VLLLDVTPLSLGIETMGGVMTTLIAKNTTIPTKHSQVFSTAEDNQSAVTIHVLQGERKRAADNKSLGQFNLDGINPAPRGMPQIEVTFDIDADGILHVSAKDKNSGKEQKITIKASSGLNEDEIQKMVRDAEANAEADRKFEELVQTRNQGDHLLHSTRKQVEEAGDKLPADDKTAIESALTALETALKGEDKAAIEAKMQELAQVSQKLME
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Allosteric coupling between the lid and interdomain linker in DnaK revealed by inhibitor binding studies.
pubmed doi rcsb
molecule tags Chaperone, peptide binding protein
source organism Escherichia coli
molecule keywords Chaperone protein dnaK
total genus 52
structure length 212
sequence length 212
chains with identical sequence B, E, F
ec nomenclature
pdb deposition date 2008-07-09
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.10 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Substrate Binding Domain Of Dnak; Chain:A; Domain 2 3dpqA02
2.60.34.10 Mainly Beta Sandwich Substrate Binding Domain Of DNAk; Chain A, domain 1 Substrate Binding Domain Of DNAk; Chain A, domain 1 3dpqA01
4EZNA 1Q5LA 4H6IA 4EZZA 4WV5A 4R5LA 4PO2A 4EZVA 1DKXA 3DPQA 3T4AG 4EZYA 4EZSA 7HSCA 4JN4A 4B9QA 4JWCA 4JNFA 4EZPA 3DPOA 1BPRA 2BPRA 1YUWA 3T48A 4EZXA 2V7YA 4EZRA 4R5KA 4R5IA 5E84A 4F00A 3DOBA 4F01A 1CKRA 3D2EA 3DPPA 1U00A 1DKYA 2QFFA 4JWEA 4R5JA 3N8EA 2OP6A 4JWIA 2KHOA 3QNJA 4EZUA 3C7NB 4H6HA 3T47A 3T46A 3T49A 4E81A 2QXLA 3L3OM 3DQGA 4WV7A 4EZTA 4EZOA 4EZWA 5TKYA 1DKZA 4JWDA 3H0XA 2WINM 4FL9A 4R5GA 4HYBA 4JNEA 4HY9A 4EZQA 3C7NA 3OHXM 3D2FA 1DG4A
chains in the Genus database with same CATH superfamily
4JL9A 3D4ZA 4JWCA 2LXYA 2V7YA 2GA9D 1TQVA 1CKRA 3T47A 4UDXX 4AZ6A 3DQGA 4FM3A 3EJRA 1SU7A 4NQIA 3ACOA 1DKZA 4KIKB 4EZZA 2QKWA 4PO2A 4EZYA 3ERCC 4EZXA 3BVWA 3EJQA 2F1BA 2Z0NA 4BNEA 2F18A 5TKYA 3ABHA 1URUA 1R5EA 4DCNC 3BLBA 2YLAA 2YIBA 2Q13A 2YI9A 4JN4A 2FYVA 2V0OA 3Q84A 3BUBA 3C7NB 2D1LA 3ER9B 3KAWA 2YIAA 1ZYLA 3VEAA 3UITA 1X04A 2YI8A 4R5LA 2F7PA 7HSCA 1HXKA 2Q12A 2ZXQA 4IWOA 3BUDA 3DOBA 1TQUA 2YL5A 5KBPA 3L3OM 3BVUA 1SU8A 3BUPA 1E2UA 1YWMA 4ILHB 3CAZA 4HR1B 4FZSA 2WYIA 4WPCA 4B9QA 3RPMA 3DX1A 1BPRA 4EZRA 2EFLA 4R5KA 3QA8A 3G9GA 4R5JA 3LLLA 4ILIA 3T49A 2YL8A 3SOGA 4M0MA 4EZQA 3C7NA 1SU6A 5FIGA 2PMRA 2ND0A 2EX3B 1O7DC 3M3WA 2X3WA 2YL6A 3DYTA 3D2EA 2KHOA 3B51X 3D4YA 3O3OB 4WV7A 3ZEFA 4HY9A 2ELBA 1DG4A 4IWPA 3T4AG 4HR1A 2YKTA 4JWEA 1SUFA 4I43A 2OP6A 4FZOA 4EZOA 3KDRA 3FD9A 1I4TA 2ND1A 4AZBA 4MQDA 3OHXM 4I1QA 2OZNB 4EZSA 4NSWA 4E3CA 2X5CA 1TQWA 3B52X 1R34A 3DPPA 3T46A 2O0I1 2OBLA 2QXLA 2Z0OA 2F7QA 3D51A 3CV5A 3HAIA 4IW0A 4JWDA 3BVTA 3GI7A 4R5GA 4JLCA 2EWFA 3O3NB 3F7WA 3DX0A 3CZSA 1JQKA 1O7DB 3I39X 3DPOA 3LVTA 3EJPA 2N3KA 4R5IA 1MJGA 5E84A 4F00A 1Y2OA 2QFFA 2RAJA 1UPXA 4AZCA 1I4DA 2OW7A 4EZTA 2F7RA 2F7OA 4DYLA 4IM3A 3HAJA 1QWNA 4ATMA 3QE6A 2BPRA 2Z8YA 3HAHA 3LMFA 4EZUA 2OBMA 1QWUA 1WDZA 2X3VA 1OA0A 1OAOA 3D2FA 1I49A 3O3MB 4AZHA 1Q5LA 3A98A 4EZVA 2OW6A 1QX1A 1E9VA 2WYHA 4JNFA 3EJTA 3BVVA 2RAIA 3CVRA 3I2WA 2RT6A 3D50A 4IM0A 4ILGA 4H6HA 3PLTA 1GN9A 1X03A 4JNEA 3DDFA 1GNLA 1HWWA 4AZCB 2GF4A 3I01A 4F01A 1U00A 3Q0KA 4UDYX 4IWQA 2EFKA 3N8EA 1HTYA 2YLLA 4E81A 3D52A 3VKHA 2WINM 3L3PA 1E1DA 4NPHA 3CZNA 4AKVA 3OK8A 4AZIA 4EZNA 4WV5A 3DPQA 4H8SA 2NCZA 3RV0A 2FICA 3DDGA 3SYVA 1TQSA 3T48A 3DX2A 2F1AA 5C5BB 2YIVX 3SBTB 3QWEA 4AVMA 4AZ7A 2GAFD 2RAKA 3ER8C 4HYBA 3I04A 1R33A 3H0XA 1DKXA 1ZWWA 4D8JA 4EZPA 2D4CA 3EJSA 2JNKA 5FLEX 3RV1A 4G6QA 3QNIA 3VEBA 3CKDA 3BUQA 3ZEDA 4AZ5A 2MI7A 2ALWA 2JNSA 4H6IA 1OA1A 4FZPA 1I4LA 4KIKA 2X3XA 1YUWA 2Z0VA 1W9MA 1DKYA 4JWIA 5C5BA 4EZWA 1LQ7A 1TQTA 4AZGA 2PY6A 2LM0A 2C08A 3BVXA 3DX3A 3BUIA 3B53X 3DX4A 1GNTA 1PS3A 2OO2A 3QNJA 4WPEA 3OWGA 3KAVA 3EJUA 4IM2A 4FL9A 2YL9A 3SBSA
chains in the Genus database with same CATH topology
4JL9A 4EZNA 4WV5A 3DPQA 2NCZA 3RV0A 4B9QA 1JQKA 4JWCA 3I39X 3DPOA 1BPRA 3T48A 3SBSA 2V7YA 4EZRA 2GA9D 2N3KA 4R5KA 1MJGA 4R5IA 5E84A 4F00A 3QA8A 1CKRA 2QFFA 2YIVX 4R5JA 1UPXA 4ILIA 3SBTB 3T47A 3T49A 4UDXX 3DQGA 4EZTA 2GAFD 3ER8C 4FM3A 4IM3A 4HYBA 4M0MA 1SU7A 4EZQA 3I04A 3C7NA 1DKZA 1SU6A 3H0XA 4KIKB 4EZZA 4PO2A 1DKXA 4EZYA 5FIGA 4D8JA 4EZPA 2ND0A 3ERCC 2EX3B 2BPRA 4EZXA 2Z8YA 3D2EA 5FLEX 3RV1A 4G6QA 3LMFA 2KHOA 4EZUA 3B51X 3VEBA 3O3OB 2OBMA 3ZEDA 4WV7A 5TKYA 3ZEFA 1OA0A 1OAOA 4HY9A 3D2FA 1DG4A 2JNSA 3O3MB 4H6IA 1Q5LA 2YIBA 3A98A 4EZVA 1OA1A 4IWPA 3T4AG 2YI9A 4JN4A 1E9VA 4JNFA 4KIKA 1YUWA 4HR1A 1W9MA 1DKYA 4JWEA 1SUFA 2RT6A 4I43A 2OP6A 4IM0A 4JWIA 4ILGA 3C7NB 4H6HA 3ER9B 3KAWA 2YIAA 4EZOA 4EZWA 1GN9A 1ZYLA 3KDRA 3VEAA 3UITA 3FD9A 4JNEA 2PY6A 2ND1A 2LM0A 4MQDA 2YI8A 3OHXM 1GNLA 4R5LA 4EZSA 3B53X 7HSCA 1GNTA 4E3CA 2X5CA 3B52X 4IWOA 3I01A 3DOBA 4F01A 3DPPA 1U00A 4UDYX 4IWQA 3N8EA 3QNJA 3T46A 2OBLA 4E81A 2QXLA 3L3OM 3OWGA 1SU8A 4IW0A 1E2UA 4JWDA 3VKHA 2WINM 3KAVA 3GI7A 4IM2A 4R5GA 4FL9A 4JLCA 2EWFA 3O3NB 1E1DA 4NPHA 4ILHB 3F7WA 4HR1B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4EZN A;  1Q5L A;  4H6I A;  4EZZ A;  4WV5 A;  4R5L A;  4PO2 A;  4EZV A;  1DKX A;  3DPQ A;  3T4A G;  4EZY A;  4EZS A;  7HSC A;  4JN4 A;  4B9Q A;  4JWC A;  4JNF A;  4EZP A;  3DPO A;  1BPR A;  2BPR A;  1YUW A;  3T48 A;  4EZX A;  2V7Y A;  4EZR A;  4R5K A;  4R5I A;  5E84 A;  4F00 A;  3DOB A;  4F01 A;  1CKR A;  3D2E A;  3DPP A;  1U00 A;  1DKY A;  2QFF A;  4JWE A;  4R5J A;  3N8E A;  2OP6 A;  4JWI A;  2KHO A;  3QNJ A;  4EZU A;  3C7N B;  4H6H A;  3T47 A;  3T46 A;  3T49 A;  4E81 A;  2QXL A;  3L3O M;  3DQG A;  4WV7 A;  4EZT A;  4EZO A;  4EZW A;  5TKY A;  1DKZ A;  4JWD A;  3H0X A;  2WIN M;  4FL9 A;  4R5G A;  4HYB A;  4JNE A;  4HY9 A;  4EZQ A;  3C7N A;  3OHX M;  3D2F A;  1DG4 A; 
#chains in the Genus database with same CATH topology
 4JL9 A;  3D4Z A;  4JWC A;  2LXY A;  2V7Y A;  2GA9 D;  1TQV A;  1CKR A;  3T47 A;  4UDX X;  4AZ6 A;  3DQG A;  4FM3 A;  3EJR A;  1SU7 A;  4NQI A;  3ACO A;  1DKZ A;  4KIK B;  4EZZ A;  2QKW A;  4PO2 A;  4EZY A;  3ERC C;  4EZX A;  3BVW A;  3EJQ A;  2F1B A;  2Z0N A;  4BNE A;  2F18 A;  5TKY A;  3ABH A;  1URU A;  1R5E A;  4DCN C;  3BLB A;  2YLA A;  2YIB A;  2Q13 A;  2YI9 A;  4JN4 A;  2FYV A;  2V0O A;  3Q84 A;  3BUB A;  3C7N B;  2D1L A;  3ER9 B;  3KAW A;  2YIA A;  1ZYL A;  3VEA A;  3UIT A;  1X04 A;  2YI8 A;  4R5L A;  2F7P A;  7HSC A;  1HXK A;  2Q12 A;  2ZXQ A;  4IWO A;  3BUD A;  3DOB A;  1TQU A;  2YL5 A;  5KBP A;  3L3O M;  3BVU A;  1SU8 A;  3BUP A;  1E2U A;  1YWM A;  4ILH B;  3CAZ A;  4HR1 B;  4FZS A;  2WYI A;  4WPC A;  4B9Q A;  3RPM A;  3DX1 A;  1BPR A;  4EZR A;  2EFL A;  4R5K A;  3QA8 A;  3G9G A;  4R5J A;  3LLL A;  4ILI A;  3T49 A;  2YL8 A;  3SOG A;  4M0M A;  4EZQ A;  3C7N A;  1SU6 A;  5FIG A;  2PMR A;  2ND0 A;  2EX3 B;  1O7D C;  3M3W A;  2X3W A;  2YL6 A;  3DYT A;  3D2E A;  2KHO A;  3B51 X;  3D4Y A;  3O3O B;  4WV7 A;  3ZEF A;  4HY9 A;  2ELB A;  1DG4 A;  4IWP A;  3T4A G;  4HR1 A;  2YKT A;  4JWE A;  1SUF A;  4I43 A;  2OP6 A;  4FZO A;  4EZO A;  3KDR A;  3FD9 A;  1I4T A;  2ND1 A;  4AZB A;  4MQD A;  3OHX M;  4I1Q A;  2OZN B;  4EZS A;  4NSW A;  4E3C A;  2X5C A;  1TQW A;  3B52 X;  1R34 A;  3DPP A;  3T46 A;  2O0I 1;  2OBL A;  2QXL A;  2Z0O A;  2F7Q A;  3D51 A;  3CV5 A;  3HAI A;  4IW0 A;  4JWD A;  3BVT A;  3GI7 A;  4R5G A;  4JLC A;  2EWF A;  3O3N B;  3F7W A;  3DX0 A;  3CZS A;  1JQK A;  1O7D B;  3I39 X;  3DPO A;  3LVT A;  3EJP A;  2N3K A;  4R5I A;  1MJG A;  5E84 A;  4F00 A;  1Y2O A;  2QFF A;  2RAJ A;  1UPX A;  4AZC A;  1I4D A;  2OW7 A;  4EZT A;  2F7R A;  2F7O A;  4DYL A;  4IM3 A;  3HAJ A;  1QWN A;  4ATM A;  3QE6 A;  2BPR A;  2Z8Y A;  3HAH A;  3LMF A;  4EZU A;  2OBM A;  1QWU A;  1WDZ A;  2X3V A;  1OA0 A;  1OAO A;  3D2F A;  1I49 A;  3O3M B;  4AZH A;  1Q5L A;  3A98 A;  4EZV A;  2OW6 A;  1QX1 A;  1E9V A;  2WYH A;  4JNF A;  3EJT A;  3BVV A;  2RAI A;  3CVR A;  3I2W A;  2RT6 A;  3D50 A;  4IM0 A;  4ILG A;  4H6H A;  3PLT A;  1GN9 A;  1X03 A;  4JNE A;  3DDF A;  1GNL A;  1HWW A;  4AZC B;  2GF4 A;  3I01 A;  4F01 A;  1U00 A;  3Q0K A;  4UDY X;  4IWQ A;  2EFK A;  3N8E A;  1HTY A;  2YLL A;  4E81 A;  3D52 A;  3VKH A;  2WIN M;  3L3P A;  1E1D A;  4NPH A;  3CZN A;  4AKV A;  3OK8 A;  4AZI A;  4EZN A;  4WV5 A;  3DPQ A;  4H8S A;  2NCZ A;  3RV0 A;  2FIC A;  3DDG A;  3SYV A;  1TQS A;  3T48 A;  3DX2 A;  2F1A A;  5C5B B;  2YIV X;  3SBT B;  3QWE A;  4AVM A;  4AZ7 A;  2GAF D;  2RAK A;  3ER8 C;  4HYB A;  3I04 A;  1R33 A;  3H0X A;  1DKX A;  1ZWW A;  4D8J A;  4EZP A;  2D4C A;  3EJS A;  2JNK A;  5FLE X;  3RV1 A;  4G6Q A;  3QNI A;  3VEB A;  3CKD A;  3BUQ A;  3ZED A;  4AZ5 A;  2MI7 A;  2ALW A;  2JNS A;  4H6I A;  1OA1 A;  4FZP A;  1I4L A;  4KIK A;  2X3X A;  1YUW A;  2Z0V A;  1W9M A;  1DKY A;  4JWI A;  5C5B A;  4EZW A;  1LQ7 A;  1TQT A;  4AZG A;  2PY6 A;  2LM0 A;  2C08 A;  3BVX A;  3DX3 A;  3BUI A;  3B53 X;  3DX4 A;  1GNT A;  1PS3 A;  2OO2 A;  3QNJ A;  4WPE A;  3OWG A;  3KAV A;  3EJU A;  4IM2 A;  4FL9 A;  2YL9 A;  3SBS A; 
#chains in the Genus database with same CATH homology
 4JL9 A;  4EZN A;  4WV5 A;  3DPQ A;  2NCZ A;  3RV0 A;  4B9Q A;  1JQK A;  4JWC A;  3I39 X;  3DPO A;  1BPR A;  3T48 A;  3SBS A;  2V7Y A;  4EZR A;  2GA9 D;  2N3K A;  4R5K A;  1MJG A;  4R5I A;  5E84 A;  4F00 A;  3QA8 A;  1CKR A;  2QFF A;  2YIV X;  4R5J A;  1UPX A;  4ILI A;  3SBT B;  3T47 A;  3T49 A;  4UDX X;  3DQG A;  4EZT A;  2GAF D;  3ER8 C;  4FM3 A;  4IM3 A;  4HYB A;  4M0M A;  1SU7 A;  4EZQ A;  3I04 A;  3C7N A;  1DKZ A;  1SU6 A;  3H0X A;  4KIK B;  4EZZ A;  4PO2 A;  1DKX A;  4EZY A;  5FIG A;  4D8J A;  4EZP A;  2ND0 A;  3ERC C;  2EX3 B;  2BPR A;  4EZX A;  2Z8Y A;  3D2E A;  5FLE X;  3RV1 A;  4G6Q A;  3LMF A;  2KHO A;  4EZU A;  3B51 X;  3VEB A;  3O3O B;  2OBM A;  3ZED A;  4WV7 A;  5TKY A;  3ZEF A;  1OA0 A;  1OAO A;  4HY9 A;  3D2F A;  1DG4 A;  2JNS A;  3O3M B;  4H6I A;  1Q5L A;  2YIB A;  3A98 A;  4EZV A;  1OA1 A;  4IWP A;  3T4A G;  2YI9 A;  4JN4 A;  1E9V A;  4JNF A;  4KIK A;  1YUW A;  4HR1 A;  1W9M A;  1DKY A;  4JWE A;  1SUF A;  2RT6 A;  4I43 A;  2OP6 A;  4IM0 A;  4JWI A;  4ILG A;  3C7N B;  4H6H A;  3ER9 B;  3KAW A;  2YIA A;  4EZO A;  4EZW A;  1GN9 A;  1ZYL A;  3KDR A;  3VEA A;  3UIT A;  3FD9 A;  4JNE A;  2PY6 A;  2ND1 A;  2LM0 A;  4MQD A;  2YI8 A;  3OHX M;  1GNL A;  4R5L A;  4EZS A;  3B53 X;  7HSC A;  1GNT A;  4E3C A;  2X5C A;  3B52 X;  4IWO A;  3I01 A;  3DOB A;  4F01 A;  3DPP A;  1U00 A;  4UDY X;  4IWQ A;  3N8E A;  3QNJ A;  3T46 A;  2OBL A;  4E81 A;  2QXL A;  3L3O M;  3OWG A;  1SU8 A;  4IW0 A;  1E2U A;  4JWD A;  3VKH A;  2WIN M;  3KAV A;  3GI7 A;  4IM2 A;  4R5G A;  4FL9 A;  4JLC A;  2EWF A;  3O3N B;  1E1D A;  4NPH A;  4ILH B;  3F7W A;  4HR1 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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