The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
343
|
sequence length |
1015
|
structure length |
1015
|
Chain Sequence |
CQDVVQDVPNVDVQMLELYDRMSFKDIDGGVWKQGWNIKYDPLKYNAHHKLKVFVVPHSHNDPGWIQTFEEYYQHDTKHILSNALRHLHDNPEMKFIWAEISYFARFYHDLGENKKLQMKSIVKNGQLEFVTGGWVMPDEANSHWRNVLLQLTEGQTWLKQFMNVTPTASWAIDPFGHSPTMPYILQKSGFKNMLIQRTHYSVKKELAQQRQLEFLWRQIWDNKGDTALFTHMMPFYSYDIPHTCGPDPKVCCQFDFKRMGSFGLSCPWKVPPRTISDQNVAARSDLLVDQWKKKAELYRTNVLLIPLGDDFRFKQNTEWDVQRVNYERLFEHINSQAHFNVQAQFGTLQEYFDAVHQAERAGQAEFPTLSGDFFTYADRSDNYWSGYYTSRPYHKRMDRVLMHYVRAAEMLSAWHSWDGMARIEERLEQARRELSLFQHHDGITGTAKTHVVVDYEQRMQEALKACQMVMQQSVYRLLTKPSIYSPDFSFSYFTLDDSRWPGSGVEDSRTTIILGEDILPSKHVVMHNTLPHWREQLVDFYVSSPFVSVTDLANNPVEAQVSPVWSWHHDTLTKTIHPQGSTTKYRIIFKARVPPMGLATYVLTISDSKPEHTSYASNLLLRKNPTSLPLGQYPEDVKFGDPREISLRVGNGPTLAFSEQGLLKSIQLTQDSPHVPVHFKFLKYGVRSHGDRSGAYLFLPNGPASPVELGQPVVLVTKGKLESSVSVGLPSVVHQTIMRGGAPEIRNLVDIGSLDNTEIVMRLETHIDSGDIFYTDLNGLQFIKRRRLDKLPLQANYYPIPSGMFIEDANTRLTLLTGQPLGGSSLASGELEIMQDRRLASDDERGLGQGVLDNKPVLHIYRLVLEKVNNCVRPSKLHPAGYLTSAAHKASQSLLDPLDKFIFAENEWIGAQGQFGGDHPSAREDLDVSVMRRLTKSSAKTQRVGYVLHRTNLMQCGTPEEHTQKLDVCHLLPNVARCERTTLTFLQNLEHLDGMVAPEVCPMETAAYVSSHSS
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
The molecular basis of inhibition of Golgi alpha-mannosidase II by mannostatin A.
pubmed doi rcsb |
| molecule tags |
Hydrolase
|
| source organism |
Drosophila melanogaster
|
| molecule keywords |
Alpha-mannosidase 2
|
| total genus |
343
|
| structure length |
1015
|
| sequence length |
1015
|
| ec nomenclature |
ec
3.2.1.114: Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase. |
| pdb deposition date | 2008-07-23 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF01074 | Glyco_hydro_38N | Glycosyl hydrolases family 38 N-terminal domain |
| A | PF07748 | Glyco_hydro_38C | Glycosyl hydrolases family 38 C-terminal domain |
| A | PF09261 | Alpha-mann_mid | Alpha mannosidase middle domain |
| A | PF18230 | Glyc_hyd_38C_2 | Glycosyl hydrolases family 38 C-terminal sub-domain |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Mainly Alpha | Up-down Bundle | Substrate Binding Domain Of Dnak; Chain:A; Domain 2 | Glycoside hydrolase family 38, central domain | ||
| Mainly Beta | Sandwich | Immunoglobulin-like | Golgi alpha-mannosidase II | ||
| Mainly Beta | Sandwich | Immunoglobulin-like | Immunoglobulin-like | ||
| Mainly Beta | Distorted Sandwich | Beta-galactosidase; Chain A, domain 5 | Golgi alpha-mannosidase II; domain 4 | ||
| Alpha Beta | Alpha-Beta Barrel | 7-stranded beta/alpha barrel | Glycoside hydrolase 38, N terminal domain |
