3EDZA

Crystal structure of catalytic domain of tace with hydroxamate inhibitor
Total Genus 80
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
80
sequence length
258
structure length
258
Chain Sequence
PDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYGGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Discovery of novel hydroxamates as highly potent tumor necrosis factor-alpha converting enzyme inhibitors. Part II: optimization of the S3' pocket.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords ADAM 17
total genus 80
structure length 258
sequence length 258
chains with identical sequence B
ec nomenclature ec 3.4.24.86: ADAM 17 endopeptidase.
pdb deposition date 2008-09-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF13688 Reprolysin_5 Metallo-peptidase family M12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 3edzA00
3OHLA 3L0TA 5L79A 3WV2A 4PKQA 2OY4A 3LE9A 5BPAA 1ZTQA 3HBVP 3LK8A 2OXZA 3F19A 4FXQA 2TCLA 4WKIA 2OI0A 4HX3A 5I0LA 2OW9A 1DTHA 2JNPA 1G05A 1GE6A 2OZRA 4L19A 2MZIA 4XM6A 4I03A 456CA 3KMEA 1WNIA 2CLTA 4H2EA 2W0DA 2HU6A 3LJZA 4GWMA 1Y0VA 1B3DA 4DV8A 1CAQA 3AIGA 3EWJA 3LQBA 4WZVA 4H3XA 2RJPA 3ELMA 2EROA 1JIZA 5L7FA 3TSKA 1YOUA 3ZUKA 1CGFA 2K9CA 2DW2A 4ON1A 1OO9A 3E8RA 1FM1A 1XFUA 4AIGA 3LUMA 3EHYA 1G4KA 4I35A 2W12A 1CGLA 3ZXHA 1PWPA 3F17A 1Z3JA 3NX7A 1EB6A 2OW2A 3K7LA 4GUYA 3DPEA 966CA 5CZMA 2AIGP 4FVLA 3F16A 1MMQA 5I43A 1K7QA 3L0VA 1AF0A 3UVCA 1B8YA 2OXUA 1HTDA 5I3MA 4H1QA 1C8TA 3RTTA 4WF6A 1GXDA 2AYKA 1FBLA 5I12A 3LIRA 1ZS0A 1MMBA 1UTTA 1KUIA 4AYKA 3GBOA 3O64A 4JP4A 3VTGA 5B5PA 1I76A 3LQ0A 1D5JA 1ZXCA 4XCTA 1FLSA 4XBHA 1HY7A 4GWNA 1QIAA 4GF1A 1BQOA 1OM8A 2DW0A 3OHOA 1GE7A 1SMPA 1BKCE 1CGEA 1O0TA 2D1NA 1UMSA 2Z2DA 4AXQA 4PKRA 1PWWA 2PJTA 1K7GA 1KUKA 3U1RA 4PKUA 3EDIA 1XFWA 2DDFA 2DW1A 1IAGA 1USNA 4L6TA 1CXVA 4JQGA 3V96B 3B92A 1XUCA 4J4MA 1SLMA 3P24A 2QPJA 1OMJA 3KEKA 4JA1A 3I7GA 1ZVXA 1KBCA 4IUWA 3LMCA 1YCMA 1YQYA 1G9KA 5BOYA 3TT4A 3AYUA 1QUAA 1HOVA 3HDBA 1R55A 2L0RA 2WOAA 1AYKA 4H49A 2OVZA 1KAPP 2MZEA 4XM7A 2MLSA 2FV9A 3EHXA 1QJJA 1KUHA 3P1VA 5I4OA 2WO9A 5CUHA 1C7KA 3EDGA 1PWQA 3EDZA 4L63A 3HBUP 1ZP5A 1R1HA 3HB2P 1KUFA 4DD8A 4EFSA 1XFVA 4R3VA 3HY7A 1GO8P 1CK7A 2JT5A 3DPFA 4H30A 1D8FA 5H8XA 5D1SA 1EUBA 4H82A 3BA0A 4PKWA 3DNGA 1PWUA 1HFCA 1PWVA 3F1AA 2X7MA 3N2UA 1L6JA 1JH1A 4G9LA 3HY9A 1BUDA 2X3CA 1MMRA 1K7IA 1H71P 3LJGA 3MA2A 4H76A 2DDYA 1EAKA 2E3XA 2MLRA 4JPAA 4WKEA 1SLNA 2WO8A 2KRJA 5D3CA 1MMPA 3G42A 3LUNA 1Y8JA 2OVXA 3USNA 5B5OA 3KMCA 4A7BA 3F18A 1OM6A 3N2VA 1JIWP 2YIGA 1IAEA 5D1TA 1G12A 2Y6DA 4GR0A 2A8HA 2X3BA 2O3EA 1CQRA 2JT6A 2CKIA 1XFXA 4IN9A 4AUOA 3WV1A 1UEAA 2XS3A 4PKTA 1BKCI 1BQQM 1YP1A 4PKVA 2YB9A 1OS9A 4G0DA 3O2XA 5JMYA 1BIWA 3WV3A 3VI1A 830CA 1QICA 1QJIA 4IJOA 4QKZA 2J0TA 1XUDA 3AYKA 1XFYA 3I7IA 2OXWA 1GKCA 4GR3A 1A86A 1OS2A 1SRPA 1GKDA 2Y6CA 3CKIA 1JJ9A 2XS4A 3SHIA 1JKYA 2OW1A 2O36A 2X3AA 1ZXVA 4HMAA 4WK7A 2W14A 1JANA 2K2GA 2W13A 2MZHA 1UTZA 3F15A 2OY2A 3Q2HA 3KRYA 4H84A 1MNCA 3RTSA 3KECA 3DSLA 4Q1LA 1XFZA 2N8RA 3LIKA 4DF9A 3G5CA 1UMTA 3HDAP 1I73A 3DL1A 3Q2GA 1C3IA 1SU3A 3KWVC 3LJTA 1G49A 1CIZA 4ZR5A 2RJQA 4GR8A 5BOTA 3K7NA 2V4BA 4FU4A 3DWBA 1J7NA 2ERPA 1ND1A 3TS4A 1R1JA 1BSWA 1IACA 3EDHA 4ILWD 4PKSA 1OM7A 1S4BP 4JIJA 1GE5A 2E2DA 4XM8A 4DPEA 3ZVSA 1IAAA 2J83A 5D1UA 3LILA 1I1IP 1XURA 5I2ZA 3LGPA 1R1IA 1JK3A 2W15A 3B8ZA 1BUVM 5CXAA 3LKAA 2ERQA 2I47A 3LEAA 5D7WA 1IABA 5LABA 1KUGA 1IADA 3KHIA 2OW0A 2SRTA 1ATLA 2JSDA 2JIHA 4A3WA 2USNA 1ASTA 1D8MA 1JAQA 1Q3AA 1DMTA 1O0QA 1R54A 1HV5A 4GQLA 3KEJA 1BZSA 1BM6A 3TVCA 1A85A 1BKCA 1QIBA 1D7XA 1JAPA 1AKLA 1SATA 4CTHA 1RM8A 3HYGA 3B2ZA 2POJA 4FXYP 2D1OA 1GO7P 1RMZA 1JAOA 1Y93A 1HFSA 5D2BA 1ROSA 2FV5A
chains in the Genus database with same CATH superfamily
3OHLA 3L0TA 5L79A 3WV2A 4PKQA 2OY4A 3LE9A 5BPAA 1ZTQA 3HBVP 3LK8A 2OXZA 3F19A 4FXQA 2TCLA 4WKIA 2OI0A 4HX3A 5I0LA 2OW9A 1DTHA 2JNPA 1G05A 1GE6A 2OZRA 4L19A 2MZIA 4XM6A 4I03A 456CA 3KMEA 3DTKA 1WNIA 2CLTA 4H2EA 2W0DA 2HU6A 3LJZA 4GWMA 1Y0VA 1B3DA 4DV8A 1CAQA 3AIGA 3EWJA 3LQBA 4WZVA 4H3XA 2RJPA 3ELMA 2EROA 1JIZA 5L7FA 3TSKA 1YOUA 3ZUKA 1CGFA 2K9CA 2DW2A 4ON1A 1OO9A 3E8RA 1FM1A 1XFUA 4AIGA 3LUMA 3EHYA 1G4KA 4I35A 2W12A 1CGLA 3ZXHA 1PWPA 3F17A 1Z3JA 3NX7A 1EB6A 4L7AA 2OW2A 3K7LA 4GUYA 3DPEA 966CA 5CZMA 2AIGP 4FVLA 3F16A 1MMQA 5I43A 1K7QA 3L0VA 1AF0A 3UVCA 1B8YA 2OXUA 1HTDA 5I3MA 4H1QA 1C8TA 3RTTA 4WF6A 1GXDA 2AYKA 1FBLA 5I12A 3LIRA 1ZS0A 1MMBA 1UTTA 1KUIA 4AYKA 3GBOA 3O64A 4JP4A 3VTGA 5B5PA 1I76A 3LQ0A 1D5JA 1OZ9A 1ZXCA 1FLSA 4XCTA 4XBHA 1HY7A 4GWNA 1QIAA 4GF1A 3DTIA 1BQOA 1OM8A 2DW0A 3OHOA 1GE7A 1SMPA 1BKCE 1CGEA 1O0TA 2D1NA 1UMSA 2Z2DA 4AXQA 4PKRA 1PWWA 2PJTA 1K7GA 1KUKA 3U1RA 4PKUA 3EDIA 1XFWA 2DDFA 2DW1A 1IAGA 1USNA 4L6TA 1CXVA 4JQGA 3V96B 3B92A 1XUCA 4J4MA 1SLMA 3P24A 2QPJA 1OMJA 3KEKA 4JA1A 3I7GA 1ZVXA 1KBCA 4IUWA 3LMCA 1YCMA 1YQYA 1G9KA 5BOYA 3TT4A 3AYUA 1QUAA 2YUFA 1HOVA 3HDBA 1R55A 2L0RA 2WOAA 1AYKA 4H49A 2OVZA 1KAPP 2MZEA 4XM7A 2MLSA 2FV9A 3EHXA 1QJJA 1KUHA 3P1VA 5I4OA 2WO9A 5CUHA 1C7KA 3EDGA 1PWQA 3EDZA 4L63A 3HBUP 1ZP5A 1R1HA 3HB2P 1KUFA 4DD8A 4EFSA 1XFVA 4R3VA 3HY7A 1GO8P 1CK7A 2JT5A 3DPFA 4H30A 1D8FA 5H8XA 5D1SA 1EUBA 4H82A 3BA0A 4PKWA 3DNGA 1PWUA 1HFCA 1PWVA 3F1AA 2X7MA 3N2UA 1L6JA 1JH1A 4G9LA 3HY9A 1BUDA 2X3CA 1MMRA 1K7IA 1H71P 3LJGA 3MA2A 4H76A 2DDYA 1EAKA 2E3XA 2MLRA 4JPAA 4WKEA 1SLNA 2WO8A 2KRJA 5D3CA 1MMPA 3G42A 3LUNA 1Y8JA 2OVXA 3USNA 5B5OA 3KMCA 4A7BA 3F18A 1OM6A 3N2VA 1JIWP 2YIGA 1IAEA 5D1TA 1G12A 2Y6DA 4GR0A 2A8HA 2X3BA 2O3EA 1CQRA 2JT6A 2CKIA 1XFXA 4IN9A 4AUOA 3WV1A 1UEAA 2XS3A 4PKTA 1BKCI 1BQQM 1YP1A 4PKVA 2YB9A 1OS9A 4G0DA 3O2XA 5JMYA 1BIWA 3WV3A 3VI1A 830CA 1QICA 1QJIA 4IJOA 4QKZA 2J0TA 1XUDA 3AYKA 1XFYA 3I7IA 2OXWA 1GKCA 4GR3A 1A86A 1OS2A 1SRPA 1GKDA 2Y6CA 3CKIA 1JJ9A 2XS4A 3SHIA 1JKYA 2OW1A 2O36A 2X3AA 1ZXVA 4HMAA 1XAXA 4WK7A 2W14A 1JANA 1XM5A 2K2GA 2W13A 2MZHA 3DTEA 1UTZA 3F15A 1TVIA 2OY2A 3Q2HA 3KRYA 4H84A 1MNCA 3RTSA 3KECA 3DSLA 4Q1LA 1XFZA 2N8RA 3LIKA 4DF9A 3G5CA 1UMTA 3HDAP 1I73A 3DL1A 3Q2GA 1C3IA 1SU3A 3KWVC 3LJTA 1G49A 1CIZA 4ZR5A 2RJQA 4GR8A 5BOTA 3K7NA 2V4BA 4FU4A 3DWBA 1J7NA 2ERPA 1ND1A 3TS4A 1R1JA 1BSWA 1IACA 3EDHA 4ILWD 4PKSA 1OM7A 1S4BP 4JIJA 1GE5A 2E2DA 4XM8A 4DPEA 3ZVSA 1IAAA 2J83A 5D1UA 3LILA 1I1IP 1XURA 5I2ZA 3LGPA 1R1IA 1JK3A 2W15A 3B8ZA 1BUVM 5CXAA 3LKAA 2ERQA 2I47A 3LEAA 5D7WA 1IABA 5LABA 1KUGA 1IADA 3KHIA 2OW0A 2SRTA 1ATLA 2JSDA 2JIHA 4A3WA 2USNA 1ASTA 1D8MA 1JAQA 1Q3AA 1DMTA 1O0QA 1R54A 1HV5A 4GQLA 3KEJA 1BZSA 1BM6A 3TVCA 1A85A 1BKCA 1QIBA 1D7XA 1JAPA 1AKLA 1SATA 4CTHA 1RM8A 3HYGA 3B2ZA 2POJA 4FXYP 2D1OA 1GO7P 1RMZA 1JAOA 1Y93A 1HFSA 5D2BA 1ROSA 2FV5A
chains in the Genus database with same CATH topology
3OHLA 3L0TA 5L79A 3WV2A 4PKQA 2OY4A 3LE9A 5BPAA 1ZTQA 3HBVP 3LK8A 2OXZA 3F19A 4FXQA 2TCLA 4WKIA 2OI0A 4HX3A 5I0LA 2OW9A 1DTHA 2JNPA 1G05A 1GE6A 2OZRA 4L19A 2MZIA 4XM6A 4I03A 456CA 3KMEA 3DTKA 1WNIA 2CLTA 4H2EA 2W0DA 2HU6A 3LJZA 4GWMA 1Y0VA 1B3DA 4DV8A 1CAQA 3AIGA 3EWJA 3LQBA 4WZVA 4H3XA 2RJPA 3ELMA 2EROA 1JIZA 5L7FA 3TSKA 1YOUA 3ZUKA 1CGFA 2K9CA 2DW2A 4ON1A 1OO9A 3E8RA 1FM1A 1XFUA 4AIGA 3LUMA 3EHYA 1G4KA 4I35A 2W12A 1CGLA 3ZXHA 1PWPA 3F17A 1Z3JA 3NX7A 1EB6A 4L7AA 2OW2A 3K7LA 4GUYA 3DPEA 966CA 5CZMA 2AIGP 4FVLA 3F16A 1MMQA 5I43A 1K7QA 3L0VA 1AF0A 3UVCA 1B8YA 2OXUA 1HTDA 5I3MA 4H1QA 1C8TA 3RTTA 4WF6A 1GXDA 2AYKA 1FBLA 5I12A 3LIRA 1ZS0A 1MMBA 1UTTA 1KUIA 4AYKA 3GBOA 3O64A 4JP4A 3VTGA 5B5PA 1I76A 3LQ0A 1D5JA 1ZXCA 4XCTA 1FLSA 4XBHA 1HY7A 4GWNA 1QIAA 4GF1A 3DTIA 1BQOA 1OM8A 2DW0A 3OHOA 1GE7A 1SMPA 1BKCE 1CGEA 1O0TA 2D1NA 1UMSA 2Z2DA 4AXQA 4PKRA 1PWWA 2PJTA 1K7GA 1KUKA 3U1RA 4PKUA 3EDIA 1XFWA 2DDFA 2DW1A 1IAGA 1USNA 4L6TA 1CXVA 4JQGA 3V96B 3B92A 1XUCA 4J4MA 1SLMA 3P24A 2QPJA 1OMJA 3KEKA 4JA1A 3I7GA 1ZVXA 1KBCA 4IUWA 3LMCA 1YCMA 1YQYA 1G9KA 5BOYA 3TT4A 3AYUA 1QUAA 2YUFA 1HOVA 3HDBA 1R55A 2L0RA 2WOAA 1AYKA 4H49A 2OVZA 1KAPP 2MZEA 4XM7A 2MLSA 2FV9A 3EHXA 1QJJA 1KUHA 3P1VA 5I4OA 2WO9A 5CUHA 1C7KA 3EDGA 1PWQA 3EDZA 4L63A 3HBUP 1ZP5A 1R1HA 3HB2P 1KUFA 4DD8A 4EFSA 1XFVA 4R3VA 3HY7A 1GO8P 1CK7A 2JT5A 3DPFA 4H30A 1D8FA 5H8XA 5D1SA 1EUBA 4H82A 3BA0A 4PKWA 3DNGA 1PWUA 1HFCA 1PWVA 3F1AA 2X7MA 3N2UA 1L6JA 1JH1A 4G9LA 3HY9A 1BUDA 2X3CA 1MMRA 1K7IA 1H71P 3LJGA 3MA2A 4H76A 2DDYA 1EAKA 2E3XA 2MLRA 4JPAA 4WKEA 1SLNA 2WO8A 2KRJA 5D3CA 1MMPA 3G42A 3LUNA 1Y8JA 2OVXA 3USNA 5B5OA 3KMCA 4A7BA 3F18A 1OM6A 3N2VA 1JIWP 2YIGA 1IAEA 5D1TA 1G12A 2Y6DA 4GR0A 2A8HA 2X3BA 2O3EA 1CQRA 2JT6A 2CKIA 1XFXA 4IN9A 4AUOA 3WV1A 1UEAA 2XS3A 4PKTA 1BKCI 1BQQM 1YP1A 4PKVA 2YB9A 1OS9A 4G0DA 3O2XA 5JMYA 1BIWA 3WV3A 3VI1A 830CA 1QICA 1QJIA 4IJOA 4QKZA 2J0TA 1XUDA 3AYKA 1XFYA 3I7IA 2OXWA 1GKCA 4GR3A 1A86A 1OS2A 1SRPA 1GKDA 2Y6CA 3CKIA 1JJ9A 2XS4A 3SHIA 1JKYA 2OW1A 2O36A 2X3AA 1ZXVA 4HMAA 4WK7A 2W14A 1JANA 2K2GA 2W13A 2MZHA 3DTEA 1UTZA 3F15A 2OY2A 3Q2HA 3KRYA 4H84A 1MNCA 3RTSA 3KECA 3DSLA 4Q1LA 1XFZA 2N8RA 3LIKA 4DF9A 3G5CA 1UMTA 3HDAP 1I73A 3DL1A 3Q2GA 1C3IA 1SU3A 3KWVC 3LJTA 1G49A 1CIZA 4ZR5A 2RJQA 4GR8A 5BOTA 3K7NA 2V4BA 4FU4A 3DWBA 1J7NA 2ERPA 1ND1A 3TS4A 1R1JA 1BSWA 1IACA 3EDHA 4ILWD 4PKSA 1OM7A 1S4BP 4JIJA 1GE5A 2E2DA 4XM8A 4DPEA 3ZVSA 1IAAA 2J83A 5D1UA 3LILA 1I1IP 1XURA 5I2ZA 3LGPA 1R1IA 1JK3A 2W15A 3B8ZA 1BUVM 5CXAA 3LKAA 2ERQA 2I47A 3LEAA 5D7WA 1IABA 5LABA 1KUGA 1IADA 3KHIA 2OW0A 2SRTA 1ATLA 2JSDA 2JIHA 4A3WA 2USNA 1ASTA 1D8MA 1JAQA 1Q3AA 1DMTA 1O0QA 1R54A 1HV5A 4GQLA 3KEJA 1BZSA 1BM6A 3TVCA 1A85A 1BKCA 1QIBA 1D7XA 1JAPA 1AKLA 1SATA 4CTHA 1RM8A 3HYGA 3B2ZA 2POJA 4FXYP 2D1OA 1GO7P 1RMZA 1JAOA 1Y93A 1HFSA 5D2BA 1ROSA 2FV5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3OHL A;  3L0T A;  5L79 A;  3WV2 A;  4PKQ A;  2OY4 A;  3LE9 A;  5BPA A;  1ZTQ A;  3HBV P;  3LK8 A;  2OXZ A;  3F19 A;  4FXQ A;  2TCL A;  4WKI A;  2OI0 A;  4HX3 A;  5I0L A;  2OW9 A;  1DTH A;  2JNP A;  1G05 A;  1GE6 A;  2OZR A;  4L19 A;  2MZI A;  4XM6 A;  4I03 A;  456C A;  3KME A;  1WNI A;  2CLT A;  4H2E A;  2W0D A;  2HU6 A;  3LJZ A;  4GWM A;  1Y0V A;  1B3D A;  4DV8 A;  1CAQ A;  3AIG A;  3EWJ A;  3LQB A;  4WZV A;  4H3X A;  2RJP A;  3ELM A;  2ERO A;  1JIZ A;  5L7F A;  3TSK A;  1YOU A;  3ZUK A;  1CGF A;  2K9C A;  2DW2 A;  4ON1 A;  1OO9 A;  3E8R A;  1FM1 A;  1XFU A;  4AIG A;  3LUM A;  3EHY A;  1G4K A;  4I35 A;  2W12 A;  1CGL A;  3ZXH A;  1PWP A;  3F17 A;  1Z3J A;  3NX7 A;  1EB6 A;  2OW2 A;  3K7L A;  4GUY A;  3DPE A;  966C A;  5CZM A;  2AIG P;  4FVL A;  3F16 A;  1MMQ A;  5I43 A;  1K7Q A;  3L0V A;  1AF0 A;  3UVC A;  1B8Y A;  2OXU A;  1HTD A;  5I3M A;  4H1Q A;  1C8T A;  3RTT A;  4WF6 A;  1GXD A;  2AYK A;  1FBL A;  5I12 A;  3LIR A;  1ZS0 A;  1MMB A;  1UTT A;  1KUI A;  4AYK A;  3GBO A;  3O64 A;  4JP4 A;  3VTG A;  5B5P A;  1I76 A;  3LQ0 A;  1D5J A;  1ZXC A;  4XCT A;  1FLS A;  4XBH A;  1HY7 A;  4GWN A;  1QIA A;  4GF1 A;  1BQO A;  1OM8 A;  2DW0 A;  3OHO A;  1GE7 A;  1SMP A;  1BKC E;  1CGE A;  1O0T A;  2D1N A;  1UMS A;  2Z2D A;  4AXQ A;  4PKR A;  1PWW A;  2PJT A;  1K7G A;  1KUK A;  3U1R A;  4PKU A;  3EDI A;  1XFW A;  2DDF A;  2DW1 A;  1IAG A;  1USN A;  4L6T A;  1CXV A;  4JQG A;  3V96 B;  3B92 A;  1XUC A;  4J4M A;  1SLM A;  3P24 A;  2QPJ A;  1OMJ A;  3KEK A;  4JA1 A;  3I7G A;  1ZVX A;  1KBC A;  4IUW A;  3LMC A;  1YCM A;  1YQY A;  1G9K A;  5BOY A;  3TT4 A;  3AYU A;  1QUA A;  1HOV A;  3HDB A;  1R55 A;  2L0R A;  2WOA A;  1AYK A;  4H49 A;  2OVZ A;  1KAP P;  2MZE A;  4XM7 A;  2MLS A;  2FV9 A;  3EHX A;  1QJJ A;  1KUH A;  3P1V A;  5I4O A;  2WO9 A;  5CUH A;  1C7K A;  3EDG A;  1PWQ A;  3EDZ A;  4L63 A;  3HBU P;  1ZP5 A;  1R1H A;  3HB2 P;  1KUF A;  4DD8 A;  4EFS A;  1XFV A;  4R3V A;  3HY7 A;  1GO8 P;  1CK7 A;  2JT5 A;  3DPF A;  4H30 A;  1D8F A;  5H8X A;  5D1S A;  1EUB A;  4H82 A;  3BA0 A;  4PKW A;  3DNG A;  1PWU A;  1HFC A;  1PWV A;  3F1A A;  2X7M A;  3N2U A;  1L6J A;  1JH1 A;  4G9L A;  3HY9 A;  1BUD A;  2X3C A;  1MMR A;  1K7I A;  1H71 P;  3LJG A;  3MA2 A;  4H76 A;  2DDY A;  1EAK A;  2E3X A;  2MLR A;  4JPA A;  4WKE A;  1SLN A;  2WO8 A;  2KRJ A;  5D3C A;  1MMP A;  3G42 A;  3LUN A;  1Y8J A;  2OVX A;  3USN A;  5B5O A;  3KMC A;  4A7B A;  3F18 A;  1OM6 A;  3N2V A;  1JIW P;  2YIG A;  1IAE A;  5D1T A;  1G12 A;  2Y6D A;  4GR0 A;  2A8H A;  2X3B A;  2O3E A;  1CQR A;  2JT6 A;  2CKI A;  1XFX A;  4IN9 A;  4AUO A;  3WV1 A;  1UEA A;  2XS3 A;  4PKT A;  1BKC I;  1BQQ M;  1YP1 A;  4PKV A;  2YB9 A;  1OS9 A;  4G0D A;  3O2X A;  5JMY A;  1BIW A;  3WV3 A;  3VI1 A;  830C A;  1QIC A;  1QJI A;  4IJO A;  4QKZ A;  2J0T A;  1XUD A;  3AYK A;  1XFY A;  3I7I A;  2OXW A;  1GKC A;  4GR3 A;  1A86 A;  1OS2 A;  1SRP A;  1GKD A;  2Y6C A;  3CKI A;  1JJ9 A;  2XS4 A;  3SHI A;  1JKY A;  2OW1 A;  2O36 A;  2X3A A;  1ZXV A;  4HMA A;  4WK7 A;  2W14 A;  1JAN A;  2K2G A;  2W13 A;  2MZH A;  1UTZ A;  3F15 A;  2OY2 A;  3Q2H A;  3KRY A;  4H84 A;  1MNC A;  3RTS A;  3KEC A;  3DSL A;  4Q1L A;  1XFZ A;  2N8R A;  3LIK A;  4DF9 A;  3G5C A;  1UMT A;  3HDA P;  1I73 A;  3DL1 A;  3Q2G A;  1C3I A;  1SU3 A;  3KWV C;  3LJT A;  1G49 A;  1CIZ A;  4ZR5 A;  2RJQ A;  4GR8 A;  5BOT A;  3K7N A;  2V4B A;  4FU4 A;  3DWB A;  1J7N A;  2ERP A;  1ND1 A;  3TS4 A;  1R1J A;  1BSW A;  1IAC A;  3EDH A;  4ILW D;  4PKS A;  1OM7 A;  1S4B P;  4JIJ A;  1GE5 A;  2E2D A;  4XM8 A;  4DPE A;  3ZVS A;  1IAA A;  2J83 A;  5D1U A;  3LIL A;  1I1I P;  1XUR A;  5I2Z A;  3LGP A;  1R1I A;  1JK3 A;  2W15 A;  3B8Z A;  1BUV M;  5CXA A;  3LKA A;  2ERQ A;  2I47 A;  3LEA A;  5D7W A;  1IAB A;  5LAB A;  1KUG A;  1IAD A;  3KHI A;  2OW0 A;  2SRT A;  1ATL A;  2JSD A;  2JIH A;  4A3W A;  2USN A;  1AST A;  1D8M A;  1JAQ A;  1Q3A A;  1DMT A;  1O0Q A;  1R54 A;  1HV5 A;  4GQL A;  3KEJ A;  1BZS A;  1BM6 A;  3TVC A;  1A85 A;  1BKC A;  1QIB A;  1D7X A;  1JAP A;  1AKL A;  1SAT A;  4CTH A;  1RM8 A;  3HYG A;  3B2Z A;  2POJ A;  4FXY P;  2D1O A;  1GO7 P;  1RMZ A;  1JAO A;  1Y93 A;  1HFS A;  5D2B A;  1ROS A;  2FV5 A; 
#chains in the Genus database with same CATH topology
 3OHL A;  3L0T A;  5L79 A;  3WV2 A;  4PKQ A;  2OY4 A;  3LE9 A;  5BPA A;  1ZTQ A;  3HBV P;  3LK8 A;  2OXZ A;  3F19 A;  4FXQ A;  2TCL A;  4WKI A;  2OI0 A;  4HX3 A;  5I0L A;  2OW9 A;  1DTH A;  2JNP A;  1G05 A;  1GE6 A;  2OZR A;  4L19 A;  2MZI A;  4XM6 A;  4I03 A;  456C A;  3KME A;  3DTK A;  1WNI A;  2CLT A;  4H2E A;  2W0D A;  2HU6 A;  3LJZ A;  4GWM A;  1Y0V A;  1B3D A;  4DV8 A;  1CAQ A;  3AIG A;  3EWJ A;  3LQB A;  4WZV A;  4H3X A;  2RJP A;  3ELM A;  2ERO A;  1JIZ A;  5L7F A;  3TSK A;  1YOU A;  3ZUK A;  1CGF A;  2K9C A;  2DW2 A;  4ON1 A;  1OO9 A;  3E8R A;  1FM1 A;  1XFU A;  4AIG A;  3LUM A;  3EHY A;  1G4K A;  4I35 A;  2W12 A;  1CGL A;  3ZXH A;  1PWP A;  3F17 A;  1Z3J A;  3NX7 A;  1EB6 A;  4L7A A;  2OW2 A;  3K7L A;  4GUY A;  3DPE A;  966C A;  5CZM A;  2AIG P;  4FVL A;  3F16 A;  1MMQ A;  5I43 A;  1K7Q A;  3L0V A;  1AF0 A;  3UVC A;  1B8Y A;  2OXU A;  1HTD A;  5I3M A;  4H1Q A;  1C8T A;  3RTT A;  4WF6 A;  1GXD A;  2AYK A;  1FBL A;  5I12 A;  3LIR A;  1ZS0 A;  1MMB A;  1UTT A;  1KUI A;  4AYK A;  3GBO A;  3O64 A;  4JP4 A;  3VTG A;  5B5P A;  1I76 A;  3LQ0 A;  1D5J A;  1OZ9 A;  1ZXC A;  1FLS A;  4XCT A;  4XBH A;  1HY7 A;  4GWN A;  1QIA A;  4GF1 A;  3DTI A;  1BQO A;  1OM8 A;  2DW0 A;  3OHO A;  1GE7 A;  1SMP A;  1BKC E;  1CGE A;  1O0T A;  2D1N A;  1UMS A;  2Z2D A;  4AXQ A;  4PKR A;  1PWW A;  2PJT A;  1K7G A;  1KUK A;  3U1R A;  4PKU A;  3EDI A;  1XFW A;  2DDF A;  2DW1 A;  1IAG A;  1USN A;  4L6T A;  1CXV A;  4JQG A;  3V96 B;  3B92 A;  1XUC A;  4J4M A;  1SLM A;  3P24 A;  2QPJ A;  1OMJ A;  3KEK A;  4JA1 A;  3I7G A;  1ZVX A;  1KBC A;  4IUW A;  3LMC A;  1YCM A;  1YQY A;  1G9K A;  5BOY A;  3TT4 A;  3AYU A;  1QUA A;  2YUF A;  1HOV A;  3HDB A;  1R55 A;  2L0R A;  2WOA A;  1AYK A;  4H49 A;  2OVZ A;  1KAP P;  2MZE A;  4XM7 A;  2MLS A;  2FV9 A;  3EHX A;  1QJJ A;  1KUH A;  3P1V A;  5I4O A;  2WO9 A;  5CUH A;  1C7K A;  3EDG A;  1PWQ A;  3EDZ A;  4L63 A;  3HBU P;  1ZP5 A;  1R1H A;  3HB2 P;  1KUF A;  4DD8 A;  4EFS A;  1XFV A;  4R3V A;  3HY7 A;  1GO8 P;  1CK7 A;  2JT5 A;  3DPF A;  4H30 A;  1D8F A;  5H8X A;  5D1S A;  1EUB A;  4H82 A;  3BA0 A;  4PKW A;  3DNG A;  1PWU A;  1HFC A;  1PWV A;  3F1A A;  2X7M A;  3N2U A;  1L6J A;  1JH1 A;  4G9L A;  3HY9 A;  1BUD A;  2X3C A;  1MMR A;  1K7I A;  1H71 P;  3LJG A;  3MA2 A;  4H76 A;  2DDY A;  1EAK A;  2E3X A;  2MLR A;  4JPA A;  4WKE A;  1SLN A;  2WO8 A;  2KRJ A;  5D3C A;  1MMP A;  3G42 A;  3LUN A;  1Y8J A;  2OVX A;  3USN A;  5B5O A;  3KMC A;  4A7B A;  3F18 A;  1OM6 A;  3N2V A;  1JIW P;  2YIG A;  1IAE A;  5D1T A;  1G12 A;  2Y6D A;  4GR0 A;  2A8H A;  2X3B A;  2O3E A;  1CQR A;  2JT6 A;  2CKI A;  1XFX A;  4IN9 A;  4AUO A;  3WV1 A;  1UEA A;  2XS3 A;  4PKT A;  1BKC I;  1BQQ M;  1YP1 A;  4PKV A;  2YB9 A;  1OS9 A;  4G0D A;  3O2X A;  5JMY A;  1BIW A;  3WV3 A;  3VI1 A;  830C A;  1QIC A;  1QJI A;  4IJO A;  4QKZ A;  2J0T A;  1XUD A;  3AYK A;  1XFY A;  3I7I A;  2OXW A;  1GKC A;  4GR3 A;  1A86 A;  1OS2 A;  1SRP A;  1GKD A;  2Y6C A;  3CKI A;  1JJ9 A;  2XS4 A;  3SHI A;  1JKY A;  2OW1 A;  2O36 A;  2X3A A;  1ZXV A;  4HMA A;  1XAX A;  4WK7 A;  2W14 A;  1JAN A;  1XM5 A;  2K2G A;  2W13 A;  2MZH A;  3DTE A;  1UTZ A;  3F15 A;  1TVI A;  2OY2 A;  3Q2H A;  3KRY A;  4H84 A;  1MNC A;  3RTS A;  3KEC A;  3DSL A;  4Q1L A;  1XFZ A;  2N8R A;  3LIK A;  4DF9 A;  3G5C A;  1UMT A;  3HDA P;  1I73 A;  3DL1 A;  3Q2G A;  1C3I A;  1SU3 A;  3KWV C;  3LJT A;  1G49 A;  1CIZ A;  4ZR5 A;  2RJQ A;  4GR8 A;  5BOT A;  3K7N A;  2V4B A;  4FU4 A;  3DWB A;  1J7N A;  2ERP A;  1ND1 A;  3TS4 A;  1R1J A;  1BSW A;  1IAC A;  3EDH A;  4ILW D;  4PKS A;  1OM7 A;  1S4B P;  4JIJ A;  1GE5 A;  2E2D A;  4XM8 A;  4DPE A;  3ZVS A;  1IAA A;  2J83 A;  5D1U A;  3LIL A;  1I1I P;  1XUR A;  5I2Z A;  3LGP A;  1R1I A;  1JK3 A;  2W15 A;  3B8Z A;  1BUV M;  5CXA A;  3LKA A;  2ERQ A;  2I47 A;  3LEA A;  5D7W A;  1IAB A;  5LAB A;  1KUG A;  1IAD A;  3KHI A;  2OW0 A;  2SRT A;  1ATL A;  2JSD A;  2JIH A;  4A3W A;  2USN A;  1AST A;  1D8M A;  1JAQ A;  1Q3A A;  1DMT A;  1O0Q A;  1R54 A;  1HV5 A;  4GQL A;  3KEJ A;  1BZS A;  1BM6 A;  3TVC A;  1A85 A;  1BKC A;  1QIB A;  1D7X A;  1JAP A;  1AKL A;  1SAT A;  4CTH A;  1RM8 A;  3HYG A;  3B2Z A;  2POJ A;  4FXY P;  2D1O A;  1GO7 P;  1RMZ A;  1JAO A;  1Y93 A;  1HFS A;  5D2B A;  1ROS A;  2FV5 A; 
#chains in the Genus database with same CATH homology
 3OHL A;  3L0T A;  5L79 A;  3WV2 A;  4PKQ A;  2OY4 A;  3LE9 A;  5BPA A;  1ZTQ A;  3HBV P;  3LK8 A;  2OXZ A;  3F19 A;  4FXQ A;  2TCL A;  4WKI A;  2OI0 A;  4HX3 A;  5I0L A;  2OW9 A;  1DTH A;  2JNP A;  1G05 A;  1GE6 A;  2OZR A;  4L19 A;  2MZI A;  4XM6 A;  4I03 A;  456C A;  3KME A;  3DTK A;  1WNI A;  2CLT A;  4H2E A;  2W0D A;  2HU6 A;  3LJZ A;  4GWM A;  1Y0V A;  1B3D A;  4DV8 A;  1CAQ A;  3AIG A;  3EWJ A;  3LQB A;  4WZV A;  4H3X A;  2RJP A;  3ELM A;  2ERO A;  1JIZ A;  5L7F A;  3TSK A;  1YOU A;  3ZUK A;  1CGF A;  2K9C A;  2DW2 A;  4ON1 A;  1OO9 A;  3E8R A;  1FM1 A;  1XFU A;  4AIG A;  3LUM A;  3EHY A;  1G4K A;  4I35 A;  2W12 A;  1CGL A;  3ZXH A;  1PWP A;  3F17 A;  1Z3J A;  3NX7 A;  1EB6 A;  4L7A A;  2OW2 A;  3K7L A;  4GUY A;  3DPE A;  966C A;  5CZM A;  2AIG P;  4FVL A;  3F16 A;  1MMQ A;  5I43 A;  1K7Q A;  3L0V A;  1AF0 A;  3UVC A;  1B8Y A;  2OXU A;  1HTD A;  5I3M A;  4H1Q A;  1C8T A;  3RTT A;  4WF6 A;  1GXD A;  2AYK A;  1FBL A;  5I12 A;  3LIR A;  1ZS0 A;  1MMB A;  1UTT A;  1KUI A;  4AYK A;  3GBO A;  3O64 A;  4JP4 A;  3VTG A;  5B5P A;  1I76 A;  3LQ0 A;  1D5J A;  1ZXC A;  4XCT A;  1FLS A;  4XBH A;  1HY7 A;  4GWN A;  1QIA A;  4GF1 A;  3DTI A;  1BQO A;  1OM8 A;  2DW0 A;  3OHO A;  1GE7 A;  1SMP A;  1BKC E;  1CGE A;  1O0T A;  2D1N A;  1UMS A;  2Z2D A;  4AXQ A;  4PKR A;  1PWW A;  2PJT A;  1K7G A;  1KUK A;  3U1R A;  4PKU A;  3EDI A;  1XFW A;  2DDF A;  2DW1 A;  1IAG A;  1USN A;  4L6T A;  1CXV A;  4JQG A;  3V96 B;  3B92 A;  1XUC A;  4J4M A;  1SLM A;  3P24 A;  2QPJ A;  1OMJ A;  3KEK A;  4JA1 A;  3I7G A;  1ZVX A;  1KBC A;  4IUW A;  3LMC A;  1YCM A;  1YQY A;  1G9K A;  5BOY A;  3TT4 A;  3AYU A;  1QUA A;  2YUF A;  1HOV A;  3HDB A;  1R55 A;  2L0R A;  2WOA A;  1AYK A;  4H49 A;  2OVZ A;  1KAP P;  2MZE A;  4XM7 A;  2MLS A;  2FV9 A;  3EHX A;  1QJJ A;  1KUH A;  3P1V A;  5I4O A;  2WO9 A;  5CUH A;  1C7K A;  3EDG A;  1PWQ A;  3EDZ A;  4L63 A;  3HBU P;  1ZP5 A;  1R1H A;  3HB2 P;  1KUF A;  4DD8 A;  4EFS A;  1XFV A;  4R3V A;  3HY7 A;  1GO8 P;  1CK7 A;  2JT5 A;  3DPF A;  4H30 A;  1D8F A;  5H8X A;  5D1S A;  1EUB A;  4H82 A;  3BA0 A;  4PKW A;  3DNG A;  1PWU A;  1HFC A;  1PWV A;  3F1A A;  2X7M A;  3N2U A;  1L6J A;  1JH1 A;  4G9L A;  3HY9 A;  1BUD A;  2X3C A;  1MMR A;  1K7I A;  1H71 P;  3LJG A;  3MA2 A;  4H76 A;  2DDY A;  1EAK A;  2E3X A;  2MLR A;  4JPA A;  4WKE A;  1SLN A;  2WO8 A;  2KRJ A;  5D3C A;  1MMP A;  3G42 A;  3LUN A;  1Y8J A;  2OVX A;  3USN A;  5B5O A;  3KMC A;  4A7B A;  3F18 A;  1OM6 A;  3N2V A;  1JIW P;  2YIG A;  1IAE A;  5D1T A;  1G12 A;  2Y6D A;  4GR0 A;  2A8H A;  2X3B A;  2O3E A;  1CQR A;  2JT6 A;  2CKI A;  1XFX A;  4IN9 A;  4AUO A;  3WV1 A;  1UEA A;  2XS3 A;  4PKT A;  1BKC I;  1BQQ M;  1YP1 A;  4PKV A;  2YB9 A;  1OS9 A;  4G0D A;  3O2X A;  5JMY A;  1BIW A;  3WV3 A;  3VI1 A;  830C A;  1QIC A;  1QJI A;  4IJO A;  4QKZ A;  2J0T A;  1XUD A;  3AYK A;  1XFY A;  3I7I A;  2OXW A;  1GKC A;  4GR3 A;  1A86 A;  1OS2 A;  1SRP A;  1GKD A;  2Y6C A;  3CKI A;  1JJ9 A;  2XS4 A;  3SHI A;  1JKY A;  2OW1 A;  2O36 A;  2X3A A;  1ZXV A;  4HMA A;  4WK7 A;  2W14 A;  1JAN A;  2K2G A;  2W13 A;  2MZH A;  3DTE A;  1UTZ A;  3F15 A;  2OY2 A;  3Q2H A;  3KRY A;  4H84 A;  1MNC A;  3RTS A;  3KEC A;  3DSL A;  4Q1L A;  1XFZ A;  2N8R A;  3LIK A;  4DF9 A;  3G5C A;  1UMT A;  3HDA P;  1I73 A;  3DL1 A;  3Q2G A;  1C3I A;  1SU3 A;  3KWV C;  3LJT A;  1G49 A;  1CIZ A;  4ZR5 A;  2RJQ A;  4GR8 A;  5BOT A;  3K7N A;  2V4B A;  4FU4 A;  3DWB A;  1J7N A;  2ERP A;  1ND1 A;  3TS4 A;  1R1J A;  1BSW A;  1IAC A;  3EDH A;  4ILW D;  4PKS A;  1OM7 A;  1S4B P;  4JIJ A;  1GE5 A;  2E2D A;  4XM8 A;  4DPE A;  3ZVS A;  1IAA A;  2J83 A;  5D1U A;  3LIL A;  1I1I P;  1XUR A;  5I2Z A;  3LGP A;  1R1I A;  1JK3 A;  2W15 A;  3B8Z A;  1BUV M;  5CXA A;  3LKA A;  2ERQ A;  2I47 A;  3LEA A;  5D7W A;  1IAB A;  5LAB A;  1KUG A;  1IAD A;  3KHI A;  2OW0 A;  2SRT A;  1ATL A;  2JSD A;  2JIH A;  4A3W A;  2USN A;  1AST A;  1D8M A;  1JAQ A;  1Q3A A;  1DMT A;  1O0Q A;  1R54 A;  1HV5 A;  4GQL A;  3KEJ A;  1BZS A;  1BM6 A;  3TVC A;  1A85 A;  1BKC A;  1QIB A;  1D7X A;  1JAP A;  1AKL A;  1SAT A;  4CTH A;  1RM8 A;  3HYG A;  3B2Z A;  2POJ A;  4FXY P;  2D1O A;  1GO7 P;  1RMZ A;  1JAO A;  1Y93 A;  1HFS A;  5D2B A;  1ROS A;  2FV5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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