3EDZA

Crystal structure of catalytic domain of tace with hydroxamate inhibitor
Total Genus 80
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
80
sequence length
258
structure length
258
Chain Sequence
b'PDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYGGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSN'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords ADAM 17
publication title Discovery of novel hydroxamates as highly potent tumor necrosis factor-alpha converting enzyme inhibitors. Part II: optimization of the S3' pocket.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Hydrolase
total genus 80
structure length 258
sequence length 258
chains with identical sequence B
ec nomenclature ec 3.4.24.86: ADAM 17 endopeptidase.
pdb deposition date 2008-09-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF13688 Reprolysin_5 Metallo-peptidase family M12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 3edzA00
2OVZA 1IAEA 1CGEA 4JP4A 1I73A 3MA2A 1PWPA 3NX7A 4I35A 3VI1A 2JT5A 1MMPA 1B8YA 3EDIA 1OM8A 4XM6A 4AXQA 4DD8A 1Z3JA 3LUMA 1ZTQA 2J0TA 3DSLA 2FV5A 3V96B 1IAGA 4PKTA 2W0DA 456CA 3KMCA 1MMBA 1KUIA 3E8RA 4XBHA 1EB6A 1KAPP 1JIWP 1PWQA 4WKIA 4XM8A 3LMCA 3KWVC 4IN9A 1RMZA 1UTTA 1OS9A 3F18A 3F16A 1CK7A 4HX3A 1JANA 3EHYA 1G9KA 4WZVA 2QPJA 2Z2DA 3HBUP 1RM8A 1XFXA 1GKCA 1XFYA 3Q2GA 1AF0A 1KUHA 1ROSA 3KECA 3KHIA 3LQ0A 5D3CA 4GF1A 1L6JA 4EFSA 3DPFA 3EDHA 2FV9A 3LILA 1OM6A 3ZVSA 1J7NA 1CIZA 3P24A 1XURA 4H84A 1HOVA 1G4KA 2Y6DA 1CGLA 5JMYA 2YB9A 4FXQA 2SRTA 1R54A 3LIRA 3N2VA 1FBLA 2TCLA 1C8TA 3P1VA 2OY2A 1CXVA 1I76A 2X7MA 2OY4A 1JKYA 1SLNA 1R55A 5CXAA 2OXWA 2OI0A 1HY7A 5BPAA 1C7KA 1BKCA 1HFSA 1ZXVA 5I4OA 3LUNA 4DPEA 1XFWA 2J83A 830CA 3HBVP 2DW2A 3F1AA 1Y93A 5D1UA 3UVCA 2JNPA 2CLTA 5D2BA 2DDFA 3WV1A 1XFUA 1JAPA 4PKSA 3B8ZA 1BSWA 3Q2HA 2RJQA 4ON1A 1ZXCA 2MZHA 2X3CA 2OXZA 1BKCE 5B5OA 2DDYA 1KUFA 1QUAA 1USNA 3I7GA 4H49A 2XS3A 1QIAA 4H2EA 1UMTA 2X3BA 5L7FA 1HV5A 1GKDA 2ERPA 1QJJA 3F15A 1S4BP 3HDBA 3TVCA 4A7BA 1G05A 3USNA 2A8HA 1KBCA 4GR0A 2D1OA 3G42A 1GO8P 4WK7A 3LJZA 2DW0A 1UTZA 4G9LA 5D1SA 2V4BA 4AYKA 1R1IA 2JSDA 3HY9A 1SRPA 1QIBA 4PKQA 2WO9A 2K2GA 1UMSA 2W12A 1SMPA 3L0TA 1CGFA 4AIGA 2MZIA 4L6TA 1XFVA 1PWUA 1R1HA 1DTHA 4XM7A 1IACA 2MLSA 4IUWA 2OZRA 1ATLA 3EHXA 3OHOA 4GWMA 2AIGP 4H76A 1AKLA 5I3MA 3AIGA 3AYUA 3ZXHA 4H3XA 2Y6CA 3K7LA 1YP1A 1SATA 2PJTA 1OM7A 3HDAP 3LK8A 3KRYA 4GWNA 1HFCA 3LJGA 5CUHA 1UEAA 2MLRA 1O0QA 1G49A 4ILWD 5I12A 4DF9A 1XUCA 4G0DA 3RTSA 5BOTA 3GBOA 2EROA 2W14A 3LEAA 4A3WA 3WV2A 2W13A 4WKEA 4PKWA 2N8RA 1R1JA 3EDGA 1ND1A 1IAAA 4GR3A 1BZSA 3ELMA 2K9CA 1EUBA 4GUYA 1I1IP 1BUVM 1YCMA 2HU6A 4JIJA 2L0RA 4L63A 1GXDA 3DPEA 3HY7A 1XUDA 3I7IA 4AUOA 3OHLA 4JPAA 2OVXA 3KEKA 4QKZA 1CAQA 3LIKA 3N2UA 2AYKA 1GE6A 1C3IA 1FM1A 1D8FA 1QJIA 3RTTA 3LQBA 3O2XA 1BKCI 1YQYA 2OW9A 1CQRA 1A86A 1OO9A 4GQLA 1FLSA 4R3VA 1B3DA 1KUKA 3AYKA 1ZVXA 3G5CA 2E2DA 1GO7P 3TSKA 1BUDA 5CZMA 1SLMA 2X3AA 2OW2A 3KMEA 2USNA 1JH1A 1SU3A 1HTDA 2W15A 1JAOA 4J4MA 5B5PA 1MMQA 4GR8A 4L19A 3VTGA 5D1TA 1DMTA 3F19A 1ZP5A 5H8XA 1BQQM 2KRJA 2WOAA 3HYGA 4PKUA 5I2ZA 3DWBA 4ZR5A 1GE5A 3ZUKA 4FXYP 3DNGA 4H82A 1K7QA 4FU4A 1IABA 2POJA 3CKIA 3U1RA 5I43A 1Y8JA 1K7GA 4FVLA 1ZS0A 4H1QA 1D7XA 3HB2P 3F17A 1GE7A 2I47A 3TS4A 3EWJA 1BIWA 4IJOA 2DW1A 4JQGA 2OW1A 4H30A 1JAQA 2XS4A 1ASTA 2OXUA 2WO8A 1H71P 4JA1A 3TT4A 2RJPA 3LJTA 3WV3A 4Q1LA 1A85A 1G12A 5L79A 1JIZA 1XFZA 1O0TA 1Y0VA 3L0VA 3LE9A 2D1NA 5LABA 1QICA 4WF6A 1BM6A 1YOUA 4PKRA 2JIHA 1PWVA 2ERQA 4PKVA 966CA 1OS2A 1PWWA 1BQOA 1EAKA 3O64A 1D5JA 3SHIA 4I03A 3EDZA 2JT6A 5D7WA 1K7IA 1D8MA 3LKAA 2O3EA 2YIGA 1MMRA 3BA0A 2MZEA 5BOYA 3LGPA 4HMAA 2O36A 2OW0A 2E3XA 1JJ9A 3B2ZA 3B92A 1WNIA 4CTHA 1IADA 5I0LA 1AYKA 1JK3A 3KEJA 1Q3AA 1OMJA 1MNCA 1KUGA 3DL1A 2CKIA 3K7NA 4DV8A 4XCTA
chains in the Genus database with same CATH superfamily
2OVZA 1IAEA 1CGEA 4JP4A 1I73A 3MA2A 1PWPA 3NX7A 4I35A 3VI1A 2JT5A 1MMPA 1B8YA 3EDIA 1OM8A 4XM6A 4AXQA 4DD8A 1Z3JA 3LUMA 1ZTQA 2J0TA 3DSLA 2FV5A 3V96B 1IAGA 4PKTA 2W0DA 456CA 3KMCA 1MMBA 1KUIA 3E8RA 4XBHA 1EB6A 1KAPP 1JIWP 1PWQA 4WKIA 4XM8A 3LMCA 3KWVC 4IN9A 1RMZA 1UTTA 1OS9A 3F18A 3F16A 1CK7A 4HX3A 1JANA 3EHYA 1G9KA 4WZVA 2QPJA 2Z2DA 3HBUP 1OZ9A 1RM8A 1XFXA 1GKCA 1XFYA 3Q2GA 1AF0A 1KUHA 1ROSA 3DTKA 3KECA 3KHIA 3LQ0A 5D3CA 4GF1A 1L6JA 4EFSA 3DPFA 3EDHA 2FV9A 3LILA 3DTIA 1OM6A 3ZVSA 1XM5A 1J7NA 1CIZA 3P24A 1XURA 4H84A 1HOVA 1G4KA 2Y6DA 1CGLA 5JMYA 2YB9A 4FXQA 2SRTA 1R54A 3LIRA 3N2VA 1FBLA 2TCLA 1C8TA 3P1VA 2OY2A 1CXVA 1I76A 2X7MA 2OY4A 1JKYA 1SLNA 1R55A 5CXAA 2OXWA 2OI0A 1HY7A 5BPAA 2YUFA 1C7KA 1BKCA 1HFSA 1ZXVA 5I4OA 3LUNA 4DPEA 1XFWA 2J83A 830CA 3HBVP 2DW2A 3F1AA 1Y93A 5D1UA 3UVCA 2JNPA 2CLTA 5D2BA 2DDFA 3WV1A 1XFUA 1JAPA 4PKSA 3B8ZA 1BSWA 3Q2HA 2RJQA 4ON1A 1ZXCA 2MZHA 2X3CA 2OXZA 1BKCE 5B5OA 2DDYA 1KUFA 1QUAA 1USNA 3I7GA 4H49A 2XS3A 1QIAA 4H2EA 1UMTA 2X3BA 5L7FA 1HV5A 1GKDA 2ERPA 1QJJA 3F15A 1S4BP 3HDBA 3TVCA 4A7BA 1G05A 3USNA 2A8HA 1KBCA 4GR0A 2D1OA 3G42A 1GO8P 4WK7A 3LJZA 2DW0A 1UTZA 4G9LA 5D1SA 2V4BA 4AYKA 1R1IA 2JSDA 3HY9A 1SRPA 1QIBA 4PKQA 2WO9A 2K2GA 1UMSA 2W12A 1SMPA 3L0TA 1CGFA 4AIGA 2MZIA 4L6TA 1XFVA 1PWUA 1R1HA 1DTHA 4XM7A 1IACA 2MLSA 4IUWA 2OZRA 1ATLA 3EHXA 3OHOA 4GWMA 2AIGP 4H76A 1AKLA 5I3MA 3AIGA 3AYUA 3ZXHA 4H3XA 2Y6CA 3K7LA 3DTEA 1YP1A 1SATA 2PJTA 1OM7A 3HDAP 3LK8A 3KRYA 4GWNA 1HFCA 3LJGA 5CUHA 1UEAA 2MLRA 1O0QA 1G49A 4ILWD 5I12A 4DF9A 1XUCA 4G0DA 3RTSA 5BOTA 3GBOA 2EROA 2W14A 3LEAA 4A3WA 3WV2A 2W13A 4WKEA 4PKWA 2N8RA 1R1JA 3EDGA 1ND1A 1IAAA 4GR3A 1BZSA 3ELMA 2K9CA 1EUBA 4GUYA 1I1IP 1BUVM 1YCMA 2HU6A 4JIJA 2L0RA 4L63A 1GXDA 3DPEA 3HY7A 1XUDA 3I7IA 4AUOA 3OHLA 4JPAA 2OVXA 3KEKA 4QKZA 1CAQA 3LIKA 3N2UA 2AYKA 1GE6A 1C3IA 1FM1A 1D8FA 1QJIA 3RTTA 3LQBA 1TVIA 3O2XA 1BKCI 1YQYA 2OW9A 1CQRA 1A86A 1XAXA 1OO9A 4GQLA 1FLSA 4R3VA 1B3DA 1KUKA 3AYKA 1ZVXA 3G5CA 2E2DA 1GO7P 3TSKA 1BUDA 5CZMA 1SLMA 2X3AA 2OW2A 3KMEA 2USNA 1JH1A 1SU3A 1HTDA 2W15A 1JAOA 4J4MA 5B5PA 1MMQA 4GR8A 4L19A 3VTGA 5D1TA 1DMTA 3F19A 1ZP5A 5H8XA 1BQQM 2KRJA 2WOAA 3HYGA 4PKUA 5I2ZA 3DWBA 4ZR5A 1GE5A 3ZUKA 4FXYP 3DNGA 4H82A 1K7QA 4FU4A 1IABA 2POJA 3CKIA 3U1RA 5I43A 1Y8JA 1K7GA 4FVLA 1ZS0A 4H1QA 1D7XA 3HB2P 3F17A 1GE7A 2I47A 3TS4A 3EWJA 1BIWA 4IJOA 2DW1A 4JQGA 2OW1A 4H30A 1JAQA 2XS4A 1ASTA 2OXUA 2WO8A 1H71P 4JA1A 3TT4A 2RJPA 3LJTA 4L7AA 3WV3A 4Q1LA 1A85A 1G12A 5L79A 1JIZA 1XFZA 1O0TA 1Y0VA 3L0VA 3LE9A 2D1NA 5LABA 1QICA 4WF6A 1BM6A 1YOUA 4PKRA 2JIHA 1PWVA 2ERQA 4PKVA 966CA 1OS2A 1PWWA 1BQOA 1EAKA 3O64A 1D5JA 3SHIA 4I03A 3EDZA 2JT6A 5D7WA 1K7IA 1D8MA 3LKAA 2O3EA 2YIGA 1MMRA 3BA0A 2MZEA 5BOYA 3LGPA 4HMAA 2O36A 2OW0A 2E3XA 1JJ9A 3B2ZA 3B92A 1WNIA 4CTHA 1IADA 5I0LA 1AYKA 1JK3A 3KEJA 1Q3AA 1OMJA 1MNCA 1KUGA 3DL1A 2CKIA 3K7NA 4DV8A 4XCTA
chains in the Genus database with same CATH topology
2OVZA 1IAEA 1CGEA 4JP4A 1I73A 3MA2A 1PWPA 3NX7A 4I35A 3VI1A 2JT5A 1MMPA 1B8YA 3EDIA 1OM8A 4XM6A 4AXQA 4DD8A 1Z3JA 3LUMA 1ZTQA 2J0TA 3DSLA 2FV5A 3V96B 1IAGA 4PKTA 2W0DA 456CA 3KMCA 1MMBA 1KUIA 3E8RA 4XBHA 1EB6A 1KAPP 1JIWP 1PWQA 4WKIA 4XM8A 3LMCA 3KWVC 4IN9A 1RMZA 1UTTA 1OS9A 3F18A 3F16A 1CK7A 4HX3A 1JANA 3EHYA 1G9KA 4WZVA 2QPJA 2Z2DA 3HBUP 1RM8A 1XFXA 1GKCA 1XFYA 3Q2GA 1AF0A 1KUHA 1ROSA 3DTKA 3KECA 3KHIA 3LQ0A 5D3CA 4GF1A 1L6JA 4EFSA 3DPFA 3EDHA 2FV9A 3LILA 3DTIA 1OM6A 3ZVSA 1J7NA 1CIZA 3P24A 1XURA 4H84A 1HOVA 1G4KA 2Y6DA 1CGLA 5JMYA 2YB9A 4FXQA 2SRTA 1R54A 3LIRA 3N2VA 1FBLA 2TCLA 1C8TA 3P1VA 2OY2A 1CXVA 1I76A 2X7MA 2OY4A 1JKYA 1SLNA 1R55A 5CXAA 2OXWA 2OI0A 1HY7A 5BPAA 2YUFA 1C7KA 1BKCA 1HFSA 1ZXVA 5I4OA 3LUNA 4DPEA 1XFWA 2J83A 830CA 3HBVP 2DW2A 3F1AA 1Y93A 5D1UA 3UVCA 2JNPA 2CLTA 5D2BA 2DDFA 3WV1A 1XFUA 1JAPA 4PKSA 3B8ZA 1BSWA 3Q2HA 2RJQA 4ON1A 1ZXCA 2MZHA 2X3CA 2OXZA 1BKCE 5B5OA 2DDYA 1KUFA 1QUAA 1USNA 3I7GA 4H49A 2XS3A 1QIAA 4H2EA 1UMTA 2X3BA 5L7FA 1HV5A 1GKDA 2ERPA 1QJJA 3F15A 1S4BP 3HDBA 3TVCA 4A7BA 1G05A 3USNA 2A8HA 1KBCA 4GR0A 2D1OA 3G42A 1GO8P 4WK7A 3LJZA 2DW0A 1UTZA 4G9LA 5D1SA 2V4BA 4AYKA 1R1IA 2JSDA 3HY9A 1SRPA 1QIBA 4PKQA 2WO9A 2K2GA 1UMSA 2W12A 1SMPA 3L0TA 1CGFA 4AIGA 2MZIA 4L6TA 1XFVA 1PWUA 1R1HA 1DTHA 4XM7A 1IACA 2MLSA 4IUWA 2OZRA 1ATLA 3EHXA 3OHOA 4GWMA 2AIGP 4H76A 1AKLA 5I3MA 3AIGA 3AYUA 3ZXHA 4H3XA 2Y6CA 3K7LA 3DTEA 1YP1A 1SATA 2PJTA 1OM7A 3HDAP 3LK8A 3KRYA 4GWNA 1HFCA 3LJGA 5CUHA 1UEAA 2MLRA 1O0QA 1G49A 4ILWD 5I12A 4DF9A 1XUCA 4G0DA 3RTSA 5BOTA 3GBOA 2EROA 2W14A 3LEAA 4A3WA 3WV2A 2W13A 4WKEA 4PKWA 2N8RA 1R1JA 3EDGA 1ND1A 1IAAA 4GR3A 1BZSA 3ELMA 2K9CA 1EUBA 4GUYA 1I1IP 1BUVM 1YCMA 2HU6A 4JIJA 2L0RA 4L63A 1GXDA 3DPEA 3HY7A 1XUDA 3I7IA 4AUOA 3OHLA 4JPAA 2OVXA 3KEKA 4QKZA 1CAQA 3LIKA 3N2UA 2AYKA 1GE6A 1C3IA 1FM1A 1D8FA 1QJIA 3RTTA 3LQBA 3O2XA 1BKCI 1YQYA 2OW9A 1CQRA 1A86A 1OO9A 4GQLA 1FLSA 4R3VA 1B3DA 1KUKA 3AYKA 1ZVXA 3G5CA 2E2DA 1GO7P 3TSKA 1BUDA 5CZMA 1SLMA 2X3AA 2OW2A 3KMEA 2USNA 1JH1A 1SU3A 1HTDA 2W15A 1JAOA 4J4MA 5B5PA 1MMQA 4GR8A 4L19A 3VTGA 5D1TA 1DMTA 3F19A 1ZP5A 5H8XA 1BQQM 2KRJA 2WOAA 3HYGA 4PKUA 5I2ZA 3DWBA 4ZR5A 1GE5A 3ZUKA 4FXYP 3DNGA 4H82A 1K7QA 4FU4A 1IABA 2POJA 3CKIA 3U1RA 5I43A 1Y8JA 1K7GA 4FVLA 1ZS0A 4H1QA 1D7XA 3HB2P 3F17A 1GE7A 2I47A 3TS4A 3EWJA 1BIWA 4IJOA 2DW1A 4JQGA 2OW1A 4H30A 1JAQA 2XS4A 1ASTA 2OXUA 2WO8A 1H71P 4JA1A 3TT4A 2RJPA 3LJTA 4L7AA 3WV3A 4Q1LA 1A85A 1G12A 5L79A 1JIZA 1XFZA 1O0TA 1Y0VA 3L0VA 3LE9A 2D1NA 5LABA 1QICA 4WF6A 1BM6A 1YOUA 4PKRA 2JIHA 1PWVA 2ERQA 4PKVA 966CA 1OS2A 1PWWA 1BQOA 1EAKA 3O64A 1D5JA 3SHIA 4I03A 3EDZA 2JT6A 5D7WA 1K7IA 1D8MA 3LKAA 2O3EA 2YIGA 1MMRA 3BA0A 2MZEA 5BOYA 3LGPA 4HMAA 2O36A 2OW0A 2E3XA 1JJ9A 3B2ZA 3B92A 1WNIA 4CTHA 1IADA 5I0LA 1AYKA 1JK3A 3KEJA 1Q3AA 1OMJA 1MNCA 1KUGA 3DL1A 2CKIA 3K7NA 4DV8A 4XCTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2OVZ A;  1IAE A;  1CGE A;  4JP4 A;  1I73 A;  3MA2 A;  1PWP A;  3NX7 A;  4I35 A;  3VI1 A;  2JT5 A;  1MMP A;  1B8Y A;  3EDI A;  1OM8 A;  4XM6 A;  4AXQ A;  4DD8 A;  1Z3J A;  3LUM A;  1ZTQ A;  2J0T A;  3DSL A;  2FV5 A;  3V96 B;  1IAG A;  4PKT A;  2W0D A;  456C A;  3KMC A;  1MMB A;  1KUI A;  3E8R A;  4XBH A;  1EB6 A;  1KAP P;  1JIW P;  1PWQ A;  4WKI A;  4XM8 A;  3LMC A;  3KWV C;  4IN9 A;  1RMZ A;  1UTT A;  1OS9 A;  3F18 A;  3F16 A;  1CK7 A;  4HX3 A;  1JAN A;  3EHY A;  1G9K A;  4WZV A;  2QPJ A;  2Z2D A;  3HBU P;  1RM8 A;  1XFX A;  1GKC A;  1XFY A;  3Q2G A;  1AF0 A;  1KUH A;  1ROS A;  3KEC A;  3KHI A;  3LQ0 A;  5D3C A;  4GF1 A;  1L6J A;  4EFS A;  3DPF A;  3EDH A;  2FV9 A;  3LIL A;  1OM6 A;  3ZVS A;  1J7N A;  1CIZ A;  3P24 A;  1XUR A;  4H84 A;  1HOV A;  1G4K A;  2Y6D A;  1CGL A;  5JMY A;  2YB9 A;  4FXQ A;  2SRT A;  1R54 A;  3LIR A;  3N2V A;  1FBL A;  2TCL A;  1C8T A;  3P1V A;  2OY2 A;  1CXV A;  1I76 A;  2X7M A;  2OY4 A;  1JKY A;  1SLN A;  1R55 A;  5CXA A;  2OXW A;  2OI0 A;  1HY7 A;  5BPA A;  1C7K A;  1BKC A;  1HFS A;  1ZXV A;  5I4O A;  3LUN A;  4DPE A;  1XFW A;  2J83 A;  830C A;  3HBV P;  2DW2 A;  3F1A A;  1Y93 A;  5D1U A;  3UVC A;  2JNP A;  2CLT A;  5D2B A;  2DDF A;  3WV1 A;  1XFU A;  1JAP A;  4PKS A;  3B8Z A;  1BSW A;  3Q2H A;  2RJQ A;  4ON1 A;  1ZXC A;  2MZH A;  2X3C A;  2OXZ A;  1BKC E;  5B5O A;  2DDY A;  1KUF A;  1QUA A;  1USN A;  3I7G A;  4H49 A;  2XS3 A;  1QIA A;  4H2E A;  1UMT A;  2X3B A;  5L7F A;  1HV5 A;  1GKD A;  2ERP A;  1QJJ A;  3F15 A;  1S4B P;  3HDB A;  3TVC A;  4A7B A;  1G05 A;  3USN A;  2A8H A;  1KBC A;  4GR0 A;  2D1O A;  3G42 A;  1GO8 P;  4WK7 A;  3LJZ A;  2DW0 A;  1UTZ A;  4G9L A;  5D1S A;  2V4B A;  4AYK A;  1R1I A;  2JSD A;  3HY9 A;  1SRP A;  1QIB A;  4PKQ A;  2WO9 A;  2K2G A;  1UMS A;  2W12 A;  1SMP A;  3L0T A;  1CGF A;  4AIG A;  2MZI A;  4L6T A;  1XFV A;  1PWU A;  1R1H A;  1DTH A;  4XM7 A;  1IAC A;  2MLS A;  4IUW A;  2OZR A;  1ATL A;  3EHX A;  3OHO A;  4GWM A;  2AIG P;  4H76 A;  1AKL A;  5I3M A;  3AIG A;  3AYU A;  3ZXH A;  4H3X A;  2Y6C A;  3K7L A;  1YP1 A;  1SAT A;  2PJT A;  1OM7 A;  3HDA P;  3LK8 A;  3KRY A;  4GWN A;  1HFC A;  3LJG A;  5CUH A;  1UEA A;  2MLR A;  1O0Q A;  1G49 A;  4ILW D;  5I12 A;  4DF9 A;  1XUC A;  4G0D A;  3RTS A;  5BOT A;  3GBO A;  2ERO A;  2W14 A;  3LEA A;  4A3W A;  3WV2 A;  2W13 A;  4WKE A;  4PKW A;  2N8R A;  1R1J A;  3EDG A;  1ND1 A;  1IAA A;  4GR3 A;  1BZS A;  3ELM A;  2K9C A;  1EUB A;  4GUY A;  1I1I P;  1BUV M;  1YCM A;  2HU6 A;  4JIJ A;  2L0R A;  4L63 A;  1GXD A;  3DPE A;  3HY7 A;  1XUD A;  3I7I A;  4AUO A;  3OHL A;  4JPA A;  2OVX A;  3KEK A;  4QKZ A;  1CAQ A;  3LIK A;  3N2U A;  2AYK A;  1GE6 A;  1C3I A;  1FM1 A;  1D8F A;  1QJI A;  3RTT A;  3LQB A;  3O2X A;  1BKC I;  1YQY A;  2OW9 A;  1CQR A;  1A86 A;  1OO9 A;  4GQL A;  1FLS A;  4R3V A;  1B3D A;  1KUK A;  3AYK A;  1ZVX A;  3G5C A;  2E2D A;  1GO7 P;  3TSK A;  1BUD A;  5CZM A;  1SLM A;  2X3A A;  2OW2 A;  3KME A;  2USN A;  1JH1 A;  1SU3 A;  1HTD A;  2W15 A;  1JAO A;  4J4M A;  5B5P A;  1MMQ A;  4GR8 A;  4L19 A;  3VTG A;  5D1T A;  1DMT A;  3F19 A;  1ZP5 A;  5H8X A;  1BQQ M;  2KRJ A;  2WOA A;  3HYG A;  4PKU A;  5I2Z A;  3DWB A;  4ZR5 A;  1GE5 A;  3ZUK A;  4FXY P;  3DNG A;  4H82 A;  1K7Q A;  4FU4 A;  1IAB A;  2POJ A;  3CKI A;  3U1R A;  5I43 A;  1Y8J A;  1K7G A;  4FVL A;  1ZS0 A;  4H1Q A;  1D7X A;  3HB2 P;  3F17 A;  1GE7 A;  2I47 A;  3TS4 A;  3EWJ A;  1BIW A;  4IJO A;  2DW1 A;  4JQG A;  2OW1 A;  4H30 A;  1JAQ A;  2XS4 A;  1AST A;  2OXU A;  2WO8 A;  1H71 P;  4JA1 A;  3TT4 A;  2RJP A;  3LJT A;  3WV3 A;  4Q1L A;  1A85 A;  1G12 A;  5L79 A;  1JIZ A;  1XFZ A;  1O0T A;  1Y0V A;  3L0V A;  3LE9 A;  2D1N A;  5LAB A;  1QIC A;  4WF6 A;  1BM6 A;  1YOU A;  4PKR A;  2JIH A;  1PWV A;  2ERQ A;  4PKV A;  966C A;  1OS2 A;  1PWW A;  1BQO A;  1EAK A;  3O64 A;  1D5J A;  3SHI A;  4I03 A;  3EDZ A;  2JT6 A;  5D7W A;  1K7I A;  1D8M A;  3LKA A;  2O3E A;  2YIG A;  1MMR A;  3BA0 A;  2MZE A;  5BOY A;  3LGP A;  4HMA A;  2O36 A;  2OW0 A;  2E3X A;  1JJ9 A;  3B2Z A;  3B92 A;  1WNI A;  4CTH A;  1IAD A;  5I0L A;  1AYK A;  1JK3 A;  3KEJ A;  1Q3A A;  1OMJ A;  1MNC A;  1KUG A;  3DL1 A;  2CKI A;  3K7N A;  4DV8 A;  4XCT A; 
#chains in the Genus database with same CATH topology
 2OVZ A;  1IAE A;  1CGE A;  4JP4 A;  1I73 A;  3MA2 A;  1PWP A;  3NX7 A;  4I35 A;  3VI1 A;  2JT5 A;  1MMP A;  1B8Y A;  3EDI A;  1OM8 A;  4XM6 A;  4AXQ A;  4DD8 A;  1Z3J A;  3LUM A;  1ZTQ A;  2J0T A;  3DSL A;  2FV5 A;  3V96 B;  1IAG A;  4PKT A;  2W0D A;  456C A;  3KMC A;  1MMB A;  1KUI A;  3E8R A;  4XBH A;  1EB6 A;  1KAP P;  1JIW P;  1PWQ A;  4WKI A;  4XM8 A;  3LMC A;  3KWV C;  4IN9 A;  1RMZ A;  1UTT A;  1OS9 A;  3F18 A;  3F16 A;  1CK7 A;  4HX3 A;  1JAN A;  3EHY A;  1G9K A;  4WZV A;  2QPJ A;  2Z2D A;  3HBU P;  1OZ9 A;  1RM8 A;  1XFX A;  1GKC A;  1XFY A;  3Q2G A;  1AF0 A;  1KUH A;  1ROS A;  3DTK A;  3KEC A;  3KHI A;  3LQ0 A;  5D3C A;  4GF1 A;  1L6J A;  4EFS A;  3DPF A;  3EDH A;  2FV9 A;  3LIL A;  3DTI A;  1OM6 A;  3ZVS A;  1XM5 A;  1J7N A;  1CIZ A;  3P24 A;  1XUR A;  4H84 A;  1HOV A;  1G4K A;  2Y6D A;  1CGL A;  5JMY A;  2YB9 A;  4FXQ A;  2SRT A;  1R54 A;  3LIR A;  3N2V A;  1FBL A;  2TCL A;  1C8T A;  3P1V A;  2OY2 A;  1CXV A;  1I76 A;  2X7M A;  2OY4 A;  1JKY A;  1SLN A;  1R55 A;  5CXA A;  2OXW A;  2OI0 A;  1HY7 A;  5BPA A;  2YUF A;  1C7K A;  1BKC A;  1HFS A;  1ZXV A;  5I4O A;  3LUN A;  4DPE A;  1XFW A;  2J83 A;  830C A;  3HBV P;  2DW2 A;  3F1A A;  1Y93 A;  5D1U A;  3UVC A;  2JNP A;  2CLT A;  5D2B A;  2DDF A;  3WV1 A;  1XFU A;  1JAP A;  4PKS A;  3B8Z A;  1BSW A;  3Q2H A;  2RJQ A;  4ON1 A;  1ZXC A;  2MZH A;  2X3C A;  2OXZ A;  1BKC E;  5B5O A;  2DDY A;  1KUF A;  1QUA A;  1USN A;  3I7G A;  4H49 A;  2XS3 A;  1QIA A;  4H2E A;  1UMT A;  2X3B A;  5L7F A;  1HV5 A;  1GKD A;  2ERP A;  1QJJ A;  3F15 A;  1S4B P;  3HDB A;  3TVC A;  4A7B A;  1G05 A;  3USN A;  2A8H A;  1KBC A;  4GR0 A;  2D1O A;  3G42 A;  1GO8 P;  4WK7 A;  3LJZ A;  2DW0 A;  1UTZ A;  4G9L A;  5D1S A;  2V4B A;  4AYK A;  1R1I A;  2JSD A;  3HY9 A;  1SRP A;  1QIB A;  4PKQ A;  2WO9 A;  2K2G A;  1UMS A;  2W12 A;  1SMP A;  3L0T A;  1CGF A;  4AIG A;  2MZI A;  4L6T A;  1XFV A;  1PWU A;  1R1H A;  1DTH A;  4XM7 A;  1IAC A;  2MLS A;  4IUW A;  2OZR A;  1ATL A;  3EHX A;  3OHO A;  4GWM A;  2AIG P;  4H76 A;  1AKL A;  5I3M A;  3AIG A;  3AYU A;  3ZXH A;  4H3X A;  2Y6C A;  3K7L A;  3DTE A;  1YP1 A;  1SAT A;  2PJT A;  1OM7 A;  3HDA P;  3LK8 A;  3KRY A;  4GWN A;  1HFC A;  3LJG A;  5CUH A;  1UEA A;  2MLR A;  1O0Q A;  1G49 A;  4ILW D;  5I12 A;  4DF9 A;  1XUC A;  4G0D A;  3RTS A;  5BOT A;  3GBO A;  2ERO A;  2W14 A;  3LEA A;  4A3W A;  3WV2 A;  2W13 A;  4WKE A;  4PKW A;  2N8R A;  1R1J A;  3EDG A;  1ND1 A;  1IAA A;  4GR3 A;  1BZS A;  3ELM A;  2K9C A;  1EUB A;  4GUY A;  1I1I P;  1BUV M;  1YCM A;  2HU6 A;  4JIJ A;  2L0R A;  4L63 A;  1GXD A;  3DPE A;  3HY7 A;  1XUD A;  3I7I A;  4AUO A;  3OHL A;  4JPA A;  2OVX A;  3KEK A;  4QKZ A;  1CAQ A;  3LIK A;  3N2U A;  2AYK A;  1GE6 A;  1C3I A;  1FM1 A;  1D8F A;  1QJI A;  3RTT A;  3LQB A;  1TVI A;  3O2X A;  1BKC I;  1YQY A;  2OW9 A;  1CQR A;  1A86 A;  1XAX A;  1OO9 A;  4GQL A;  1FLS A;  4R3V A;  1B3D A;  1KUK A;  3AYK A;  1ZVX A;  3G5C A;  2E2D A;  1GO7 P;  3TSK A;  1BUD A;  5CZM A;  1SLM A;  2X3A A;  2OW2 A;  3KME A;  2USN A;  1JH1 A;  1SU3 A;  1HTD A;  2W15 A;  1JAO A;  4J4M A;  5B5P A;  1MMQ A;  4GR8 A;  4L19 A;  3VTG A;  5D1T A;  1DMT A;  3F19 A;  1ZP5 A;  5H8X A;  1BQQ M;  2KRJ A;  2WOA A;  3HYG A;  4PKU A;  5I2Z A;  3DWB A;  4ZR5 A;  1GE5 A;  3ZUK A;  4FXY P;  3DNG A;  4H82 A;  1K7Q A;  4FU4 A;  1IAB A;  2POJ A;  3CKI A;  3U1R A;  5I43 A;  1Y8J A;  1K7G A;  4FVL A;  1ZS0 A;  4H1Q A;  1D7X A;  3HB2 P;  3F17 A;  1GE7 A;  2I47 A;  3TS4 A;  3EWJ A;  1BIW A;  4IJO A;  2DW1 A;  4JQG A;  2OW1 A;  4H30 A;  1JAQ A;  2XS4 A;  1AST A;  2OXU A;  2WO8 A;  1H71 P;  4JA1 A;  3TT4 A;  2RJP A;  3LJT A;  4L7A A;  3WV3 A;  4Q1L A;  1A85 A;  1G12 A;  5L79 A;  1JIZ A;  1XFZ A;  1O0T A;  1Y0V A;  3L0V A;  3LE9 A;  2D1N A;  5LAB A;  1QIC A;  4WF6 A;  1BM6 A;  1YOU A;  4PKR A;  2JIH A;  1PWV A;  2ERQ A;  4PKV A;  966C A;  1OS2 A;  1PWW A;  1BQO A;  1EAK A;  3O64 A;  1D5J A;  3SHI A;  4I03 A;  3EDZ A;  2JT6 A;  5D7W A;  1K7I A;  1D8M A;  3LKA A;  2O3E A;  2YIG A;  1MMR A;  3BA0 A;  2MZE A;  5BOY A;  3LGP A;  4HMA A;  2O36 A;  2OW0 A;  2E3X A;  1JJ9 A;  3B2Z A;  3B92 A;  1WNI A;  4CTH A;  1IAD A;  5I0L A;  1AYK A;  1JK3 A;  3KEJ A;  1Q3A A;  1OMJ A;  1MNC A;  1KUG A;  3DL1 A;  2CKI A;  3K7N A;  4DV8 A;  4XCT A; 
#chains in the Genus database with same CATH homology
 2OVZ A;  1IAE A;  1CGE A;  4JP4 A;  1I73 A;  3MA2 A;  1PWP A;  3NX7 A;  4I35 A;  3VI1 A;  2JT5 A;  1MMP A;  1B8Y A;  3EDI A;  1OM8 A;  4XM6 A;  4AXQ A;  4DD8 A;  1Z3J A;  3LUM A;  1ZTQ A;  2J0T A;  3DSL A;  2FV5 A;  3V96 B;  1IAG A;  4PKT A;  2W0D A;  456C A;  3KMC A;  1MMB A;  1KUI A;  3E8R A;  4XBH A;  1EB6 A;  1KAP P;  1JIW P;  1PWQ A;  4WKI A;  4XM8 A;  3LMC A;  3KWV C;  4IN9 A;  1RMZ A;  1UTT A;  1OS9 A;  3F18 A;  3F16 A;  1CK7 A;  4HX3 A;  1JAN A;  3EHY A;  1G9K A;  4WZV A;  2QPJ A;  2Z2D A;  3HBU P;  1RM8 A;  1XFX A;  1GKC A;  1XFY A;  3Q2G A;  1AF0 A;  1KUH A;  1ROS A;  3DTK A;  3KEC A;  3KHI A;  3LQ0 A;  5D3C A;  4GF1 A;  1L6J A;  4EFS A;  3DPF A;  3EDH A;  2FV9 A;  3LIL A;  3DTI A;  1OM6 A;  3ZVS A;  1J7N A;  1CIZ A;  3P24 A;  1XUR A;  4H84 A;  1HOV A;  1G4K A;  2Y6D A;  1CGL A;  5JMY A;  2YB9 A;  4FXQ A;  2SRT A;  1R54 A;  3LIR A;  3N2V A;  1FBL A;  2TCL A;  1C8T A;  3P1V A;  2OY2 A;  1CXV A;  1I76 A;  2X7M A;  2OY4 A;  1JKY A;  1SLN A;  1R55 A;  5CXA A;  2OXW A;  2OI0 A;  1HY7 A;  5BPA A;  2YUF A;  1C7K A;  1BKC A;  1HFS A;  1ZXV A;  5I4O A;  3LUN A;  4DPE A;  1XFW A;  2J83 A;  830C A;  3HBV P;  2DW2 A;  3F1A A;  1Y93 A;  5D1U A;  3UVC A;  2JNP A;  2CLT A;  5D2B A;  2DDF A;  3WV1 A;  1XFU A;  1JAP A;  4PKS A;  3B8Z A;  1BSW A;  3Q2H A;  2RJQ A;  4ON1 A;  1ZXC A;  2MZH A;  2X3C A;  2OXZ A;  1BKC E;  5B5O A;  2DDY A;  1KUF A;  1QUA A;  1USN A;  3I7G A;  4H49 A;  2XS3 A;  1QIA A;  4H2E A;  1UMT A;  2X3B A;  5L7F A;  1HV5 A;  1GKD A;  2ERP A;  1QJJ A;  3F15 A;  1S4B P;  3HDB A;  3TVC A;  4A7B A;  1G05 A;  3USN A;  2A8H A;  1KBC A;  4GR0 A;  2D1O A;  3G42 A;  1GO8 P;  4WK7 A;  3LJZ A;  2DW0 A;  1UTZ A;  4G9L A;  5D1S A;  2V4B A;  4AYK A;  1R1I A;  2JSD A;  3HY9 A;  1SRP A;  1QIB A;  4PKQ A;  2WO9 A;  2K2G A;  1UMS A;  2W12 A;  1SMP A;  3L0T A;  1CGF A;  4AIG A;  2MZI A;  4L6T A;  1XFV A;  1PWU A;  1R1H A;  1DTH A;  4XM7 A;  1IAC A;  2MLS A;  4IUW A;  2OZR A;  1ATL A;  3EHX A;  3OHO A;  4GWM A;  2AIG P;  4H76 A;  1AKL A;  5I3M A;  3AIG A;  3AYU A;  3ZXH A;  4H3X A;  2Y6C A;  3K7L A;  3DTE A;  1YP1 A;  1SAT A;  2PJT A;  1OM7 A;  3HDA P;  3LK8 A;  3KRY A;  4GWN A;  1HFC A;  3LJG A;  5CUH A;  1UEA A;  2MLR A;  1O0Q A;  1G49 A;  4ILW D;  5I12 A;  4DF9 A;  1XUC A;  4G0D A;  3RTS A;  5BOT A;  3GBO A;  2ERO A;  2W14 A;  3LEA A;  4A3W A;  3WV2 A;  2W13 A;  4WKE A;  4PKW A;  2N8R A;  1R1J A;  3EDG A;  1ND1 A;  1IAA A;  4GR3 A;  1BZS A;  3ELM A;  2K9C A;  1EUB A;  4GUY A;  1I1I P;  1BUV M;  1YCM A;  2HU6 A;  4JIJ A;  2L0R A;  4L63 A;  1GXD A;  3DPE A;  3HY7 A;  1XUD A;  3I7I A;  4AUO A;  3OHL A;  4JPA A;  2OVX A;  3KEK A;  4QKZ A;  1CAQ A;  3LIK A;  3N2U A;  2AYK A;  1GE6 A;  1C3I A;  1FM1 A;  1D8F A;  1QJI A;  3RTT A;  3LQB A;  3O2X A;  1BKC I;  1YQY A;  2OW9 A;  1CQR A;  1A86 A;  1OO9 A;  4GQL A;  1FLS A;  4R3V A;  1B3D A;  1KUK A;  3AYK A;  1ZVX A;  3G5C A;  2E2D A;  1GO7 P;  3TSK A;  1BUD A;  5CZM A;  1SLM A;  2X3A A;  2OW2 A;  3KME A;  2USN A;  1JH1 A;  1SU3 A;  1HTD A;  2W15 A;  1JAO A;  4J4M A;  5B5P A;  1MMQ A;  4GR8 A;  4L19 A;  3VTG A;  5D1T A;  1DMT A;  3F19 A;  1ZP5 A;  5H8X A;  1BQQ M;  2KRJ A;  2WOA A;  3HYG A;  4PKU A;  5I2Z A;  3DWB A;  4ZR5 A;  1GE5 A;  3ZUK A;  4FXY P;  3DNG A;  4H82 A;  1K7Q A;  4FU4 A;  1IAB A;  2POJ A;  3CKI A;  3U1R A;  5I43 A;  1Y8J A;  1K7G A;  4FVL A;  1ZS0 A;  4H1Q A;  1D7X A;  3HB2 P;  3F17 A;  1GE7 A;  2I47 A;  3TS4 A;  3EWJ A;  1BIW A;  4IJO A;  2DW1 A;  4JQG A;  2OW1 A;  4H30 A;  1JAQ A;  2XS4 A;  1AST A;  2OXU A;  2WO8 A;  1H71 P;  4JA1 A;  3TT4 A;  2RJP A;  3LJT A;  4L7A A;  3WV3 A;  4Q1L A;  1A85 A;  1G12 A;  5L79 A;  1JIZ A;  1XFZ A;  1O0T A;  1Y0V A;  3L0V A;  3LE9 A;  2D1N A;  5LAB A;  1QIC A;  4WF6 A;  1BM6 A;  1YOU A;  4PKR A;  2JIH A;  1PWV A;  2ERQ A;  4PKV A;  966C A;  1OS2 A;  1PWW A;  1BQO A;  1EAK A;  3O64 A;  1D5J A;  3SHI A;  4I03 A;  3EDZ A;  2JT6 A;  5D7W A;  1K7I A;  1D8M A;  3LKA A;  2O3E A;  2YIG A;  1MMR A;  3BA0 A;  2MZE A;  5BOY A;  3LGP A;  4HMA A;  2O36 A;  2OW0 A;  2E3X A;  1JJ9 A;  3B2Z A;  3B92 A;  1WNI A;  4CTH A;  1IAD A;  5I0L A;  1AYK A;  1JK3 A;  3KEJ A;  1Q3A A;  1OMJ A;  1MNC A;  1KUG A;  3DL1 A;  2CKI A;  3K7N A;  4DV8 A;  4XCT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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