3EGTA

T. brucei farnesyl diphosphate synthase complexed with bisphosphonate bph-722
Total Genus 150
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
150
sequence length
367
structure length
358
Chain Sequence
MPMQMFMQVYDEIQMFLLEELELKFDMDPNRVRYLRKMMDTTCLGGKYNRGLTVIDVAESLLSLDGARRKRVLHDACVCGWMIEFLQAHYLVEDDIMDNSVTRRGKPCWYRHPDVTVQCAINDGLLLKSWTHMMAMHFFADRPFLQDLLCRFNRVDYTTAVGQLYDVTSMFDSNKLDPDVSQPTTTDFAEFTLSNYKRIVKYKTAYYTYLLPLVMGLIVSEALPTVDMGVTEELAMLMGEYFQVQDDVMDCFTPPERLGKVGTDIQDAKCSWLAVTFLAKASSAQVAEFKANYGSGDSEKVATVRRLYEEADLQGDYVAYEAAVAEQVKELIEKLRLCSPGFAASVETLWGKTYKRQK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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publication title Lipophilic bisphosphonates as dual farnesyl/geranylgeranyl diphosphate synthase inhibitors: an X-ray and NMR investigation.
pubmed doi rcsb
molecule keywords Farnesyl pyrophosphate synthase
source organism Trypanosoma brucei
molecule tags Transferase
total genus 150
structure length 358
sequence length 367
chains with identical sequence B
ec nomenclature ec 2.5.1.10: (2E,6E)-farnesyl diphosphate synthase.
pdb deposition date 2008-09-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 3egtA00
2E90A 3N3DA 5IK6A 4DZWA 3W7FA 2ONGA 3VJEA 5B02A 3P8LA 4K10A 1RTRA 5DZ2A 4N9UA 5ER8A 4XQRF 2E8WA 2E91A 4OMHA 4LFGA 4KFAA 3WCJA 5B0LA 5JUZF 5ILKA 3LLWA 2FTZA 2J1PA 1WKZA 3ICZA 3OACB 2PS5A 4OKZA 3DYFA 3LOMA 3WSBA 3ACWA 5I1UA 4LZCA 3Q2QA 2OPMA 1VG3A 2F89F 2ZCSA 1WMWA 2PS4A 3Q2ZA 3WCDA 1HXGA 3VJ8A 3KRPB 1UBVA 4DI5A 3OABA 4H5EF 1KIZA 3ADZA 4L2XF 3TC1A 3Q30A 5IK9A 4H5CF 2DH4A 4GP1A 4HD1A 3ASXA 3ACYA 3VJCA 3WC9A 3V66A 1YYSA 3KRAB 4UMJA 3N6KF 1WY0A 3WEIA 4E9ZA 4LPHF 3V1VA 1V4EA 1PS1A 5EATA 3KB9A 4NG6A 2F94F 1JFGA 4PVYF 2ZCQA 1HM4A 5A0IA 3G4FA 5AELA 4RXEA 5CG5A 2J1OA 3WJNA 5B0IA 3LSNA 4DEMF 4GA3A 4LLTA 3DYHA 5DGMF 3NRIA 4KK2A 3M00A 5JV0F 3PYBA 2E93A 3MAVA 4E9UA 5KSXF 3IPIA 3Q1OA 4NKEA 1HM7A 2E94A 3LMDA 1RQJA 3N5JF 5DJVF 5DJPF 5JV2F 5DHKA 3P8RA 3WSAA 3WEFA 2Z4XA 4NUAA 3WEHA 1VG2A 3S9VA 1VG6A 4LZ0A 2ZEUA 2I19A 3KRCA 3WCCA 3ACXA 5B0JA 2F7MF 4KQSA 3LGZB 3V1XA 3VJ9A 3WCEA 3CC9A 3WCLA 4NFIF 3ICKA 2Z52A 3P5RA 5EROA 4JXYA 2Z4WA 5IMIA 3N3LF 4JYXA 5IMNA 5B0MA 1N21A 3ZOUA 4WK5A 3OYRA 1FPSA 5ILYA 3PKOA 5IMPA 1HX9A 3PYAA 2AELA 5IVGA 1ZW5A 3N49F 1V4JA 4KQ5A 5CG6A 5DHIA 3OACA 2E8VA 3SAEA 4KKMA 3N1WF 5ERMA 2VF6A 5ILHA 3ZMCA 4RXDA 2AZKA 4XQTF 5IL3A 3G4DA 2AEKA 4KVYA 3LG5A 2Q9YA 3TS7A 3TFNA 3KRPA 4MC8A 3VJAA 3PH7A 4OMGA 2Z50A 4EA2A 3LDWA 2EWGA 3DYGA 3LEEA 4PVXF 1V4KA 5ILIA 2Q9ZA 1UBWA 4DXJA 2P1CA 3SDUA 5HN7A 1WL0A 3KRAA 2Z4ZA 5EASA 2Z4YA 5B03A 2PS7A 3KROB 5IM1A 4KPJA 1N20A 4OGUA 1N22A 3N1VF 1N1ZA 2F8ZF 2AZJA 2AETA 2F9KF 4JVJF 3RYWA 5C05A 4GAXA 3LK5A 5AYPA 3WCGA 1YYRA 3N46F 3WCAA 3KRFB 3WEGA 3B7LA 3WCFA 3BNXA 5IN8A 3M0GA 4P0WA 4QPFA 5IL8A 5DGNF 3LGKA 3ID0A 3NPRA 2PS6A 4QXSF 1VG4A 3NF2A 1DI1A 4RYPA 2AZLA 4RXCA 3QKCA 5H9DA 2E8UA 3M02A 2E95A 4LFVF 3S4JA 1V4HA 2H8OA 3PDEA 2QISA 2ZCOA 3AQBB 3AQCB 4P0VA 2F92F 4NFKF 2Z4VA 5JV1F 2ZY1A 1WL2A 4JZBA 3WCMA 3QQVA 5DJRF 5E8HA 5E8LA 2PS8A 1RQIA 3WEKA 4LLSA 2ZEVA 3WEJA 5IKHA 4NKFA 3LVSA 4KUXA 3ZCDA 3MZVA 3NPKA 1YHKA 4KQUA 3WCBA 5ILDA 1YYTA 4LIXA 2OA6A 3ICNA 3WJOA 1HXCA 1HXAA 2OGDA 3LZ9A 2F8CF 4XQSF 3N45F 3BNYA 3M01A 1UBXA 2E8TA 3VJDA 5A0KA 2RAHA 3SDTA 2Z78A 4H5DF 4Q23A 5DW7A 3EGTA 1JFAA 4LZ3A 3VJBA 3ZMBA 1VG7A 4LUUA 4ZQ8A 5A0JA 3P5PA 4LA6A 4MC0A 5ILZA 3ICMA 3WCHA 2ONHA 5HNAA 4LXWA 1N1BA 3EZ3A 4FJQA 5HN8A 1N23A 3SDRA 4KWDA 1UBYA 4LFEA 4EA0A 3RBMA 4KVWA 3SDVA 3AE0A 4LTZA 2Q80A 3KROA 4DWGA 5B01A 3APZA 3RYEA 4DHDA 3OABB 4DWBA 4NFJF 5IKAA 5IK0A 5AHUB 1YQ7A 4JXNA 4JZXA 1DGPA 4N1ZF 5B0KA 2Z7HA 4F6XA 2O1OA 2E8XA 3KRFA 3EFQA 5B00A 3IBAA 4FP4A 3ZL6A 2E4OA 2J5CA 3P41A 3KBKA 2Z7IA 1YJ4A 5HN9A 4F6VA 3CP6A 3WE9A 5AFXA 3N0GA 3TFVA 2FORA 4LA5A 4GP2A 3TFPA 3RMGA 4F62A 4P0XA 3N0FA 1WL1A 3UCAA 3CKEA 5EAUA 3M9UA 5ILJA 5DIQF 4LOBA 4KVIA 4OKMA 3WJKA 3AQ0A 5E8KA 2Q58A 1YHLA 4KPDA 1V4IA 3SDQA 1YYUA 4LTVA 2ZCRA 4MC3A 2OPNA 3WCIA 5JA0F 4KVDA 1YYQA 1KIYA 4RNQA 4E1EA 5DGSF 4EA1A 3KRCB 4RXAA 3LJIA 1N24A 5ERNA 1WL3A 1YHMA 1EZFA 2E92A 3N5HF 4LPGF 1YV5A
chains in the Genus database with same CATH superfamily
2E90A 3N3DA 5IK6A 4DZWA 3W7FA 2ONGA 3VJEA 5B02A 3P8LA 4K10A 1RTRA 5DZ2A 4N9UA 5ER8A 4XQRF 2E8WA 2E91A 4OMHA 4LFGA 4KFAA 3WCJA 5B0LA 5JUZF 5ILKA 3LLWA 2FTZA 2J1PA 1WKZA 3ICZA 3OACB 2PS5A 4OKZA 3DYFA 3LOMA 3WSBA 3ACWA 5I1UA 4LZCA 3Q2QA 2OPMA 1VG3A 2F89F 2ZCSA 1WMWA 2PS4A 3Q2ZA 3WCDA 1HXGA 3VJ8A 3KRPB 1UBVA 4DI5A 3OABA 4H5EF 1KIZA 3ADZA 4L2XF 3TC1A 3Q30A 5IK9A 4H5CF 2DH4A 4GP1A 4HD1A 3ASXA 3ACYA 3VJCA 3WC9A 3V66A 1YYSA 3KRAB 4UMJA 3N6KF 1WY0A 3WEIA 4E9ZA 4LPHF 3V1VA 1V4EA 1PS1A 5EATA 3KB9A 4NG6A 2F94F 1JFGA 4PVYF 2ZCQA 1HM4A 5A0IA 3G4FA 5AELA 4RXEA 5CG5A 2J1OA 3WJNA 5B0IA 3LSNA 4DEMF 4GA3A 4LLTA 3DYHA 5DGMF 3NRIA 4KK2A 3M00A 5JV0F 3PYBA 2E93A 3MAVA 4E9UA 5KSXF 3IPIA 3Q1OA 4NKEA 1HM7A 2E94A 3LMDA 1RQJA 3N5JF 5DJVF 5DJPF 5JV2F 5DHKA 3P8RA 3WSAA 3WEFA 2Z4XA 4NUAA 3WEHA 1VG2A 3S9VA 1VG6A 4LZ0A 2ZEUA 2I19A 3KRCA 3WCCA 3ACXA 5B0JA 2F7MF 4KQSA 3LGZB 3V1XA 3VJ9A 3WCEA 3CC9A 3WCLA 4NFIF 3ICKA 2Z52A 3P5RA 5EROA 4JXYA 2Z4WA 5IMIA 3N3LF 4JYXA 5IMNA 5B0MA 1N21A 3ZOUA 4WK5A 3OYRA 1FPSA 5ILYA 3PKOA 5IMPA 1HX9A 3PYAA 2AELA 5IVGA 1ZW5A 3N49F 1V4JA 4KQ5A 5CG6A 5DHIA 3OACA 2E8VA 3SAEA 4KKMA 3N1WF 5ERMA 2VF6A 5ILHA 3ZMCA 4RXDA 2AZKA 4XQTF 5IL3A 3G4DA 2AEKA 4KVYA 3LG5A 2Q9YA 3TS7A 3TFNA 3KRPA 4MC8A 3VJAA 3PH7A 4OMGA 2Z50A 4EA2A 3LDWA 2EWGA 3DYGA 3LEEA 4PVXF 1V4KA 5ILIA 2Q9ZA 1UBWA 4DXJA 2P1CA 3SDUA 5HN7A 1WL0A 3KRAA 2Z4ZA 5EASA 2Z4YA 5B03A 2PS7A 3KROB 5IM1A 4KPJA 1N20A 4OGUA 1N22A 3N1VF 1N1ZA 2F8ZF 2AZJA 2AETA 2F9KF 4JVJF 3RYWA 5C05A 4GAXA 3LK5A 5AYPA 3WCGA 1YYRA 3N46F 3WCAA 3KRFB 3WEGA 3B7LA 3WCFA 3BNXA 5IN8A 3M0GA 4P0WA 4QPFA 5IL8A 5DGNF 3LGKA 3ID0A 3NPRA 2PS6A 4QXSF 1VG4A 3NF2A 1DI1A 4RYPA 2AZLA 4RXCA 3QKCA 5H9DA 2E8UA 3M02A 2E95A 4LFVF 3S4JA 1V4HA 2H8OA 3PDEA 2QISA 2ZCOA 3AQBB 3AQCB 4P0VA 2F92F 4NFKF 2Z4VA 5JV1F 2ZY1A 1WL2A 4JZBA 3WCMA 3QQVA 5DJRF 5E8HA 5E8LA 2PS8A 1RQIA 3WEKA 4LLSA 2ZEVA 3WEJA 5IKHA 4NKFA 3LVSA 4KUXA 3ZCDA 3MZVA 3NPKA 1YHKA 4KQUA 3WCBA 5ILDA 1YYTA 4LIXA 2OA6A 3ICNA 3WJOA 1HXCA 1HXAA 2OGDA 3LZ9A 2F8CF 4XQSF 3N45F 3BNYA 3M01A 1UBXA 2E8TA 3VJDA 5A0KA 2RAHA 3SDTA 2Z78A 4H5DF 4Q23A 5DW7A 3EGTA 1JFAA 4LZ3A 3VJBA 3ZMBA 1VG7A 4LUUA 4ZQ8A 5A0JA 3P5PA 4LA6A 4MC0A 5ILZA 3ICMA 3WCHA 2ONHA 5HNAA 4LXWA 1N1BA 3EZ3A 4FJQA 5HN8A 1N23A 3SDRA 4KWDA 1UBYA 4LFEA 4EA0A 3RBMA 4KVWA 3SDVA 3AE0A 4LTZA 2Q80A 3KROA 4DWGA 5B01A 3APZA 3RYEA 4DHDA 3OABB 4DWBA 4NFJF 5IKAA 5IK0A 5AHUB 1YQ7A 4JXNA 4JZXA 1DGPA 4N1ZF 5B0KA 2Z7HA 4F6XA 2O1OA 2E8XA 3KRFA 3EFQA 5B00A 3IBAA 4FP4A 3ZL6A 2E4OA 2J5CA 3P41A 3KBKA 2Z7IA 1YJ4A 5HN9A 4F6VA 3CP6A 3WE9A 5AFXA 3N0GA 3TFVA 2FORA 4LA5A 4GP2A 3TFPA 3RMGA 4F62A 4P0XA 3N0FA 1WL1A 3UCAA 3CKEA 5EAUA 3M9UA 5ILJA 5DIQF 4LOBA 4KVIA 4OKMA 3WJKA 3AQ0A 5E8KA 2Q58A 1YHLA 4KPDA 1V4IA 3SDQA 1YYUA 4LTVA 2ZCRA 4MC3A 2OPNA 3WCIA 5JA0F 4KVDA 1YYQA 1KIYA 4RNQA 4E1EA 5DGSF 4EA1A 3KRCB 4RXAA 3LJIA 1N24A 5ERNA 1WL3A 1YHMA 1EZFA 2E92A 3N5HF 4LPGF 1YV5A
chains in the Genus database with same CATH topology
2E90A 3N3DA 5IK6A 4DZWA 3W7FA 2ONGA 3VJEA 5B02A 3P8LA 4K10A 1RTRA 5DZ2A 4N9UA 5ER8A 4XQRF 2E8WA 2E91A 4OMHA 4LFGA 4KFAA 3WCJA 5B0LA 5JUZF 5ILKA 3LLWA 2FTZA 2J1PA 1WKZA 3ICZA 3OACB 2PS5A 4OKZA 3DYFA 3LOMA 3WSBA 3ACWA 5I1UA 4LZCA 3Q2QA 2OPMA 1VG3A 2F89F 2ZCSA 1WMWA 2PS4A 3Q2ZA 3WCDA 1HXGA 3VJ8A 3KRPB 1UBVA 4DI5A 3OABA 4H5EF 1KIZA 3ADZA 4L2XF 3TC1A 3Q30A 5IK9A 4H5CF 2DH4A 4GP1A 4HD1A 3ASXA 3ACYA 3VJCA 3WC9A 3V66A 1YYSA 3KRAB 4UMJA 3N6KF 1WY0A 3WEIA 4E9ZA 4LPHF 3V1VA 1V4EA 1PS1A 5EATA 3KB9A 4NG6A 2F94F 1JFGA 4PVYF 2ZCQA 1HM4A 5A0IA 3G4FA 5AELA 4RXEA 5CG5A 2J1OA 3WJNA 5B0IA 3LSNA 4DEMF 4GA3A 4LLTA 3DYHA 5DGMF 3NRIA 4KK2A 3M00A 5JV0F 3PYBA 2E93A 3MAVA 4E9UA 5KSXF 3IPIA 3Q1OA 4NKEA 1HM7A 2E94A 3LMDA 1RQJA 3N5JF 5DJVF 5DJPF 5JV2F 5DHKA 3P8RA 3WSAA 3WEFA 2Z4XA 4NUAA 3WEHA 1VG2A 3S9VA 1VG6A 4LZ0A 2ZEUA 2I19A 3KRCA 3WCCA 3ACXA 5B0JA 2F7MF 4KQSA 3LGZB 3V1XA 3VJ9A 3WCEA 3CC9A 3WCLA 4NFIF 3ICKA 2Z52A 3P5RA 5EROA 4JXYA 2Z4WA 5IMIA 3N3LF 4JYXA 5IMNA 5B0MA 1N21A 3ZOUA 4WK5A 3OYRA 1FPSA 5ILYA 3PKOA 5IMPA 1HX9A 3PYAA 2AELA 5IVGA 1ZW5A 3N49F 1V4JA 4KQ5A 5CG6A 5DHIA 3OACA 2E8VA 3SAEA 4KKMA 3N1WF 5ERMA 2VF6A 5ILHA 3ZMCA 4RXDA 2AZKA 4XQTF 5IL3A 3G4DA 2AEKA 4KVYA 3LG5A 2Q9YA 3TS7A 3TFNA 3KRPA 4MC8A 3VJAA 3PH7A 4OMGA 2Z50A 4EA2A 3LDWA 2EWGA 3DYGA 3LEEA 4PVXF 1V4KA 5ILIA 2Q9ZA 1UBWA 4DXJA 2P1CA 3SDUA 5HN7A 1WL0A 3KRAA 2Z4ZA 5EASA 2Z4YA 5B03A 2PS7A 3KROB 5IM1A 4KPJA 1N20A 4OGUA 1N22A 3N1VF 1N1ZA 2F8ZF 2AZJA 2AETA 2F9KF 4JVJF 3RYWA 5C05A 4GAXA 3LK5A 5AYPA 3WCGA 1YYRA 3N46F 3WCAA 3KRFB 3WEGA 3B7LA 3WCFA 3BNXA 5IN8A 3M0GA 4P0WA 4QPFA 5IL8A 5DGNF 3LGKA 3ID0A 3NPRA 2PS6A 4QXSF 1VG4A 3NF2A 1DI1A 4RYPA 2AZLA 4RXCA 3QKCA 5H9DA 2E8UA 3M02A 2E95A 4LFVF 3S4JA 1V4HA 2H8OA 3PDEA 2QISA 2ZCOA 3AQBB 3AQCB 4P0VA 2F92F 4NFKF 2Z4VA 5JV1F 2ZY1A 1WL2A 4JZBA 3WCMA 3QQVA 5DJRF 5E8HA 5E8LA 2PS8A 1RQIA 3WEKA 4LLSA 2ZEVA 3WEJA 5IKHA 4NKFA 3LVSA 4KUXA 3ZCDA 3MZVA 3NPKA 1YHKA 4KQUA 3WCBA 5ILDA 1YYTA 4LIXA 2OA6A 3ICNA 3WJOA 1HXCA 1HXAA 2OGDA 3LZ9A 2F8CF 4XQSF 3N45F 3BNYA 3M01A 1UBXA 2E8TA 3VJDA 5A0KA 2RAHA 3SDTA 2Z78A 4H5DF 4Q23A 5DW7A 3EGTA 1JFAA 4LZ3A 3VJBA 3ZMBA 1VG7A 4LUUA 4ZQ8A 5A0JA 3P5PA 4LA6A 4MC0A 5ILZA 3ICMA 3WCHA 2ONHA 5HNAA 4LXWA 1N1BA 3EZ3A 4FJQA 5HN8A 1N23A 3SDRA 4KWDA 1UBYA 4LFEA 4EA0A 3RBMA 4KVWA 3SDVA 3AE0A 4LTZA 2Q80A 3KROA 4DWGA 5B01A 3APZA 3RYEA 4DHDA 3OABB 4DWBA 4NFJF 5IKAA 5IK0A 5AHUB 1YQ7A 4JXNA 4JZXA 1DGPA 4N1ZF 5B0KA 2Z7HA 4F6XA 2O1OA 2E8XA 3KRFA 3EFQA 5B00A 3IBAA 4FP4A 3ZL6A 2E4OA 2J5CA 3P41A 3KBKA 2Z7IA 1YJ4A 5HN9A 4F6VA 3CP6A 3WE9A 5AFXA 3N0GA 3TFVA 2FORA 4LA5A 4GP2A 3TFPA 3RMGA 4F62A 4P0XA 3N0FA 1WL1A 3UCAA 3CKEA 5EAUA 3M9UA 5ILJA 5DIQF 4LOBA 4KVIA 4OKMA 3WJKA 3AQ0A 5E8KA 2Q58A 1YHLA 4KPDA 1V4IA 3SDQA 1YYUA 4LTVA 2ZCRA 4MC3A 2OPNA 3WCIA 5JA0F 4KVDA 1YYQA 1KIYA 4RNQA 4E1EA 5DGSF 4EA1A 3KRCB 4RXAA 3LJIA 1N24A 5ERNA 1WL3A 1YHMA 1EZFA 2E92A 3N5HF 4LPGF 1YV5A
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 2E90 A;  3N3D A;  5IK6 A;  4DZW A;  3W7F A;  2ONG A;  3VJE A;  5B02 A;  3P8L A;  4K10 A;  1RTR A;  5DZ2 A;  4N9U A;  5ER8 A;  4XQR F;  2E8W A;  2E91 A;  4OMH A;  4LFG A;  4KFA A;  3WCJ A;  5B0L A;  5JUZ F;  5ILK A;  3LLW A;  2FTZ A;  2J1P A;  1WKZ A;  3ICZ A;  3OAC B;  2PS5 A;  4OKZ A;  3DYF A;  3LOM A;  3WSB A;  3ACW A;  5I1U A;  4LZC A;  3Q2Q A;  2OPM A;  1VG3 A;  2F89 F;  2ZCS A;  1WMW A;  2PS4 A;  3Q2Z A;  3WCD A;  1HXG A;  3VJ8 A;  3KRP B;  1UBV A;  4DI5 A;  3OAB A;  4H5E F;  1KIZ A;  3ADZ A;  4L2X F;  3TC1 A;  3Q30 A;  5IK9 A;  4H5C F;  2DH4 A;  4GP1 A;  4HD1 A;  3ASX A;  3ACY A;  3VJC A;  3WC9 A;  3V66 A;  1YYS A;  3KRA B;  4UMJ A;  3N6K F;  1WY0 A;  3WEI A;  4E9Z A;  4LPH F;  3V1V A;  1V4E A;  1PS1 A;  5EAT A;  3KB9 A;  4NG6 A;  2F94 F;  1JFG A;  4PVY F;  2ZCQ A;  1HM4 A;  5A0I A;  3G4F A;  5AEL A;  4RXE A;  5CG5 A;  2J1O A;  3WJN A;  5B0I A;  3LSN A;  4DEM F;  4GA3 A;  4LLT A;  3DYH A;  5DGM F;  3NRI A;  4KK2 A;  3M00 A;  5JV0 F;  3PYB A;  2E93 A;  3MAV A;  4E9U A;  5KSX F;  3IPI A;  3Q1O A;  4NKE A;  1HM7 A;  2E94 A;  3LMD A;  1RQJ A;  3N5J F;  5DJV F;  5DJP F;  5JV2 F;  5DHK A;  3P8R A;  3WSA A;  3WEF A;  2Z4X A;  4NUA A;  3WEH A;  1VG2 A;  3S9V A;  1VG6 A;  4LZ0 A;  2ZEU A;  2I19 A;  3KRC A;  3WCC A;  3ACX A;  5B0J A;  2F7M F;  4KQS A;  3LGZ B;  3V1X A;  3VJ9 A;  3WCE A;  3CC9 A;  3WCL A;  4NFI F;  3ICK A;  2Z52 A;  3P5R A;  5ERO A;  4JXY A;  2Z4W A;  5IMI A;  3N3L F;  4JYX A;  5IMN A;  5B0M A;  1N21 A;  3ZOU A;  4WK5 A;  3OYR A;  1FPS A;  5ILY A;  3PKO A;  5IMP A;  1HX9 A;  3PYA A;  2AEL A;  5IVG A;  1ZW5 A;  3N49 F;  1V4J A;  4KQ5 A;  5CG6 A;  5DHI A;  3OAC A;  2E8V A;  3SAE A;  4KKM A;  3N1W F;  5ERM A;  2VF6 A;  5ILH A;  3ZMC A;  4RXD A;  2AZK A;  4XQT F;  5IL3 A;  3G4D A;  2AEK A;  4KVY A;  3LG5 A;  2Q9Y A;  3TS7 A;  3TFN A;  3KRP A;  4MC8 A;  3VJA A;  3PH7 A;  4OMG A;  2Z50 A;  4EA2 A;  3LDW A;  2EWG A;  3DYG A;  3LEE A;  4PVX F;  1V4K A;  5ILI A;  2Q9Z A;  1UBW A;  4DXJ A;  2P1C A;  3SDU A;  5HN7 A;  1WL0 A;  3KRA A;  2Z4Z A;  5EAS A;  2Z4Y A;  5B03 A;  2PS7 A;  3KRO B;  5IM1 A;  4KPJ A;  1N20 A;  4OGU A;  1N22 A;  3N1V F;  1N1Z A;  2F8Z F;  2AZJ A;  2AET A;  2F9K F;  4JVJ F;  3RYW A;  5C05 A;  4GAX A;  3LK5 A;  5AYP A;  3WCG A;  1YYR A;  3N46 F;  3WCA A;  3KRF B;  3WEG A;  3B7L A;  3WCF A;  3BNX A;  5IN8 A;  3M0G A;  4P0W A;  4QPF A;  5IL8 A;  5DGN F;  3LGK A;  3ID0 A;  3NPR A;  2PS6 A;  4QXS F;  1VG4 A;  3NF2 A;  1DI1 A;  4RYP A;  2AZL A;  4RXC A;  3QKC A;  5H9D A;  2E8U A;  3M02 A;  2E95 A;  4LFV F;  3S4J A;  1V4H A;  2H8O A;  3PDE A;  2QIS A;  2ZCO A;  3AQB B;  3AQC B;  4P0V A;  2F92 F;  4NFK F;  2Z4V A;  5JV1 F;  2ZY1 A;  1WL2 A;  4JZB A;  3WCM A;  3QQV A;  5DJR F;  5E8H A;  5E8L A;  2PS8 A;  1RQI A;  3WEK A;  4LLS A;  2ZEV A;  3WEJ A;  5IKH A;  4NKF A;  3LVS A;  4KUX A;  3ZCD A;  3MZV A;  3NPK A;  1YHK A;  4KQU A;  3WCB A;  5ILD A;  1YYT A;  4LIX A;  2OA6 A;  3ICN A;  3WJO A;  1HXC A;  1HXA A;  2OGD A;  3LZ9 A;  2F8C F;  4XQS F;  3N45 F;  3BNY A;  3M01 A;  1UBX A;  2E8T A;  3VJD A;  5A0K A;  2RAH A;  3SDT A;  2Z78 A;  4H5D F;  4Q23 A;  5DW7 A;  3EGT A;  1JFA A;  4LZ3 A;  3VJB A;  3ZMB A;  1VG7 A;  4LUU A;  4ZQ8 A;  5A0J A;  3P5P A;  4LA6 A;  4MC0 A;  5ILZ A;  3ICM A;  3WCH A;  2ONH A;  5HNA A;  4LXW A;  1N1B A;  3EZ3 A;  4FJQ A;  5HN8 A;  1N23 A;  3SDR A;  4KWD A;  1UBY A;  4LFE A;  4EA0 A;  3RBM A;  4KVW A;  3SDV A;  3AE0 A;  4LTZ A;  2Q80 A;  3KRO A;  4DWG A;  5B01 A;  3APZ A;  3RYE A;  4DHD A;  3OAB B;  4DWB A;  4NFJ F;  5IKA A;  5IK0 A;  5AHU B;  1YQ7 A;  4JXN A;  4JZX A;  1DGP A;  4N1Z F;  5B0K A;  2Z7H A;  4F6X A;  2O1O A;  2E8X A;  3KRF A;  3EFQ A;  5B00 A;  3IBA A;  4FP4 A;  3ZL6 A;  2E4O A;  2J5C A;  3P41 A;  3KBK A;  2Z7I A;  1YJ4 A;  5HN9 A;  4F6V A;  3CP6 A;  3WE9 A;  5AFX A;  3N0G A;  3TFV A;  2FOR A;  4LA5 A;  4GP2 A;  3TFP A;  3RMG A;  4F62 A;  4P0X A;  3N0F A;  1WL1 A;  3UCA A;  3CKE A;  5EAU A;  3M9U A;  5ILJ A;  5DIQ F;  4LOB A;  4KVI A;  4OKM A;  3WJK A;  3AQ0 A;  5E8K A;  2Q58 A;  1YHL A;  4KPD A;  1V4I A;  3SDQ A;  1YYU A;  4LTV A;  2ZCR A;  4MC3 A;  2OPN A;  3WCI A;  5JA0 F;  4KVD A;  1YYQ A;  1KIY A;  4RNQ A;  4E1E A;  5DGS F;  4EA1 A;  3KRC B;  4RXA A;  3LJI A;  1N24 A;  5ERN A;  1WL3 A;  1YHM A;  1EZF A;  2E92 A;  3N5H F;  4LPG F;  1YV5 A; 
#chains in the Genus database with same CATH topology
 2E90 A;  3N3D A;  5IK6 A;  4DZW A;  3W7F A;  2ONG A;  3VJE A;  5B02 A;  3P8L A;  4K10 A;  1RTR A;  5DZ2 A;  4N9U A;  5ER8 A;  4XQR F;  2E8W A;  2E91 A;  4OMH A;  4LFG A;  4KFA A;  3WCJ A;  5B0L A;  5JUZ F;  5ILK A;  3LLW A;  2FTZ A;  2J1P A;  1WKZ A;  3ICZ A;  3OAC B;  2PS5 A;  4OKZ A;  3DYF A;  3LOM A;  3WSB A;  3ACW A;  5I1U A;  4LZC A;  3Q2Q A;  2OPM A;  1VG3 A;  2F89 F;  2ZCS A;  1WMW A;  2PS4 A;  3Q2Z A;  3WCD A;  1HXG A;  3VJ8 A;  3KRP B;  1UBV A;  4DI5 A;  3OAB A;  4H5E F;  1KIZ A;  3ADZ A;  4L2X F;  3TC1 A;  3Q30 A;  5IK9 A;  4H5C F;  2DH4 A;  4GP1 A;  4HD1 A;  3ASX A;  3ACY A;  3VJC A;  3WC9 A;  3V66 A;  1YYS A;  3KRA B;  4UMJ A;  3N6K F;  1WY0 A;  3WEI A;  4E9Z A;  4LPH F;  3V1V A;  1V4E A;  1PS1 A;  5EAT A;  3KB9 A;  4NG6 A;  2F94 F;  1JFG A;  4PVY F;  2ZCQ A;  1HM4 A;  5A0I A;  3G4F A;  5AEL A;  4RXE A;  5CG5 A;  2J1O A;  3WJN A;  5B0I A;  3LSN A;  4DEM F;  4GA3 A;  4LLT A;  3DYH A;  5DGM F;  3NRI A;  4KK2 A;  3M00 A;  5JV0 F;  3PYB A;  2E93 A;  3MAV A;  4E9U A;  5KSX F;  3IPI A;  3Q1O A;  4NKE A;  1HM7 A;  2E94 A;  3LMD A;  1RQJ A;  3N5J F;  5DJV F;  5DJP F;  5JV2 F;  5DHK A;  3P8R A;  3WSA A;  3WEF A;  2Z4X A;  4NUA A;  3WEH A;  1VG2 A;  3S9V A;  1VG6 A;  4LZ0 A;  2ZEU A;  2I19 A;  3KRC A;  3WCC A;  3ACX A;  5B0J A;  2F7M F;  4KQS A;  3LGZ B;  3V1X A;  3VJ9 A;  3WCE A;  3CC9 A;  3WCL A;  4NFI F;  3ICK A;  2Z52 A;  3P5R A;  5ERO A;  4JXY A;  2Z4W A;  5IMI A;  3N3L F;  4JYX A;  5IMN A;  5B0M A;  1N21 A;  3ZOU A;  4WK5 A;  3OYR A;  1FPS A;  5ILY A;  3PKO A;  5IMP A;  1HX9 A;  3PYA A;  2AEL A;  5IVG A;  1ZW5 A;  3N49 F;  1V4J A;  4KQ5 A;  5CG6 A;  5DHI A;  3OAC A;  2E8V A;  3SAE A;  4KKM A;  3N1W F;  5ERM A;  2VF6 A;  5ILH A;  3ZMC A;  4RXD A;  2AZK A;  4XQT F;  5IL3 A;  3G4D A;  2AEK A;  4KVY A;  3LG5 A;  2Q9Y A;  3TS7 A;  3TFN A;  3KRP A;  4MC8 A;  3VJA A;  3PH7 A;  4OMG A;  2Z50 A;  4EA2 A;  3LDW A;  2EWG A;  3DYG A;  3LEE A;  4PVX F;  1V4K A;  5ILI A;  2Q9Z A;  1UBW A;  4DXJ A;  2P1C A;  3SDU A;  5HN7 A;  1WL0 A;  3KRA A;  2Z4Z A;  5EAS A;  2Z4Y A;  5B03 A;  2PS7 A;  3KRO B;  5IM1 A;  4KPJ A;  1N20 A;  4OGU A;  1N22 A;  3N1V F;  1N1Z A;  2F8Z F;  2AZJ A;  2AET A;  2F9K F;  4JVJ F;  3RYW A;  5C05 A;  4GAX A;  3LK5 A;  5AYP A;  3WCG A;  1YYR A;  3N46 F;  3WCA A;  3KRF B;  3WEG A;  3B7L A;  3WCF A;  3BNX A;  5IN8 A;  3M0G A;  4P0W A;  4QPF A;  5IL8 A;  5DGN F;  3LGK A;  3ID0 A;  3NPR A;  2PS6 A;  4QXS F;  1VG4 A;  3NF2 A;  1DI1 A;  4RYP A;  2AZL A;  4RXC A;  3QKC A;  5H9D A;  2E8U A;  3M02 A;  2E95 A;  4LFV F;  3S4J A;  1V4H A;  2H8O A;  3PDE A;  2QIS A;  2ZCO A;  3AQB B;  3AQC B;  4P0V A;  2F92 F;  4NFK F;  2Z4V A;  5JV1 F;  2ZY1 A;  1WL2 A;  4JZB A;  3WCM A;  3QQV A;  5DJR F;  5E8H A;  5E8L A;  2PS8 A;  1RQI A;  3WEK A;  4LLS A;  2ZEV A;  3WEJ A;  5IKH A;  4NKF A;  3LVS A;  4KUX A;  3ZCD A;  3MZV A;  3NPK A;  1YHK A;  4KQU A;  3WCB A;  5ILD A;  1YYT A;  4LIX A;  2OA6 A;  3ICN A;  3WJO A;  1HXC A;  1HXA A;  2OGD A;  3LZ9 A;  2F8C F;  4XQS F;  3N45 F;  3BNY A;  3M01 A;  1UBX A;  2E8T A;  3VJD A;  5A0K A;  2RAH A;  3SDT A;  2Z78 A;  4H5D F;  4Q23 A;  5DW7 A;  3EGT A;  1JFA A;  4LZ3 A;  3VJB A;  3ZMB A;  1VG7 A;  4LUU A;  4ZQ8 A;  5A0J A;  3P5P A;  4LA6 A;  4MC0 A;  5ILZ A;  3ICM A;  3WCH A;  2ONH A;  5HNA A;  4LXW A;  1N1B A;  3EZ3 A;  4FJQ A;  5HN8 A;  1N23 A;  3SDR A;  4KWD A;  1UBY A;  4LFE A;  4EA0 A;  3RBM A;  4KVW A;  3SDV A;  3AE0 A;  4LTZ A;  2Q80 A;  3KRO A;  4DWG A;  5B01 A;  3APZ A;  3RYE A;  4DHD A;  3OAB B;  4DWB A;  4NFJ F;  5IKA A;  5IK0 A;  5AHU B;  1YQ7 A;  4JXN A;  4JZX A;  1DGP A;  4N1Z F;  5B0K A;  2Z7H A;  4F6X A;  2O1O A;  2E8X A;  3KRF A;  3EFQ A;  5B00 A;  3IBA A;  4FP4 A;  3ZL6 A;  2E4O A;  2J5C A;  3P41 A;  3KBK A;  2Z7I A;  1YJ4 A;  5HN9 A;  4F6V A;  3CP6 A;  3WE9 A;  5AFX A;  3N0G A;  3TFV A;  2FOR A;  4LA5 A;  4GP2 A;  3TFP A;  3RMG A;  4F62 A;  4P0X A;  3N0F A;  1WL1 A;  3UCA A;  3CKE A;  5EAU A;  3M9U A;  5ILJ A;  5DIQ F;  4LOB A;  4KVI A;  4OKM A;  3WJK A;  3AQ0 A;  5E8K A;  2Q58 A;  1YHL A;  4KPD A;  1V4I A;  3SDQ A;  1YYU A;  4LTV A;  2ZCR A;  4MC3 A;  2OPN A;  3WCI A;  5JA0 F;  4KVD A;  1YYQ A;  1KIY A;  4RNQ A;  4E1E A;  5DGS F;  4EA1 A;  3KRC B;  4RXA A;  3LJI A;  1N24 A;  5ERN A;  1WL3 A;  1YHM A;  1EZF A;  2E92 A;  3N5H F;  4LPG F;  1YV5 A; 
#chains in the Genus database with same CATH homology
 2E90 A;  3N3D A;  5IK6 A;  4DZW A;  3W7F A;  2ONG A;  3VJE A;  5B02 A;  3P8L A;  4K10 A;  1RTR A;  5DZ2 A;  4N9U A;  5ER8 A;  4XQR F;  2E8W A;  2E91 A;  4OMH A;  4LFG A;  4KFA A;  3WCJ A;  5B0L A;  5JUZ F;  5ILK A;  3LLW A;  2FTZ A;  2J1P A;  1WKZ A;  3ICZ A;  3OAC B;  2PS5 A;  4OKZ A;  3DYF A;  3LOM A;  3WSB A;  3ACW A;  5I1U A;  4LZC A;  3Q2Q A;  2OPM A;  1VG3 A;  2F89 F;  2ZCS A;  1WMW A;  2PS4 A;  3Q2Z A;  3WCD A;  1HXG A;  3VJ8 A;  3KRP B;  1UBV A;  4DI5 A;  3OAB A;  4H5E F;  1KIZ A;  3ADZ A;  4L2X F;  3TC1 A;  3Q30 A;  5IK9 A;  4H5C F;  2DH4 A;  4GP1 A;  4HD1 A;  3ASX A;  3ACY A;  3VJC A;  3WC9 A;  3V66 A;  1YYS A;  3KRA B;  4UMJ A;  3N6K F;  1WY0 A;  3WEI A;  4E9Z A;  4LPH F;  3V1V A;  1V4E A;  1PS1 A;  5EAT A;  3KB9 A;  4NG6 A;  2F94 F;  1JFG A;  4PVY F;  2ZCQ A;  1HM4 A;  5A0I A;  3G4F A;  5AEL A;  4RXE A;  5CG5 A;  2J1O A;  3WJN A;  5B0I A;  3LSN A;  4DEM F;  4GA3 A;  4LLT A;  3DYH A;  5DGM F;  3NRI A;  4KK2 A;  3M00 A;  5JV0 F;  3PYB A;  2E93 A;  3MAV A;  4E9U A;  5KSX F;  3IPI A;  3Q1O A;  4NKE A;  1HM7 A;  2E94 A;  3LMD A;  1RQJ A;  3N5J F;  5DJV F;  5DJP F;  5JV2 F;  5DHK A;  3P8R A;  3WSA A;  3WEF A;  2Z4X A;  4NUA A;  3WEH A;  1VG2 A;  3S9V A;  1VG6 A;  4LZ0 A;  2ZEU A;  2I19 A;  3KRC A;  3WCC A;  3ACX A;  5B0J A;  2F7M F;  4KQS A;  3LGZ B;  3V1X A;  3VJ9 A;  3WCE A;  3CC9 A;  3WCL A;  4NFI F;  3ICK A;  2Z52 A;  3P5R A;  5ERO A;  4JXY A;  2Z4W A;  5IMI A;  3N3L F;  4JYX A;  5IMN A;  5B0M A;  1N21 A;  3ZOU A;  4WK5 A;  3OYR A;  1FPS A;  5ILY A;  3PKO A;  5IMP A;  1HX9 A;  3PYA A;  2AEL A;  5IVG A;  1ZW5 A;  3N49 F;  1V4J A;  4KQ5 A;  5CG6 A;  5DHI A;  3OAC A;  2E8V A;  3SAE A;  4KKM A;  3N1W F;  5ERM A;  2VF6 A;  5ILH A;  3ZMC A;  4RXD A;  2AZK A;  4XQT F;  5IL3 A;  3G4D A;  2AEK A;  4KVY A;  3LG5 A;  2Q9Y A;  3TS7 A;  3TFN A;  3KRP A;  4MC8 A;  3VJA A;  3PH7 A;  4OMG A;  2Z50 A;  4EA2 A;  3LDW A;  2EWG A;  3DYG A;  3LEE A;  4PVX F;  1V4K A;  5ILI A;  2Q9Z A;  1UBW A;  4DXJ A;  2P1C A;  3SDU A;  5HN7 A;  1WL0 A;  3KRA A;  2Z4Z A;  5EAS A;  2Z4Y A;  5B03 A;  2PS7 A;  3KRO B;  5IM1 A;  4KPJ A;  1N20 A;  4OGU A;  1N22 A;  3N1V F;  1N1Z A;  2F8Z F;  2AZJ A;  2AET A;  2F9K F;  4JVJ F;  3RYW A;  5C05 A;  4GAX A;  3LK5 A;  5AYP A;  3WCG A;  1YYR A;  3N46 F;  3WCA A;  3KRF B;  3WEG A;  3B7L A;  3WCF A;  3BNX A;  5IN8 A;  3M0G A;  4P0W A;  4QPF A;  5IL8 A;  5DGN F;  3LGK A;  3ID0 A;  3NPR A;  2PS6 A;  4QXS F;  1VG4 A;  3NF2 A;  1DI1 A;  4RYP A;  2AZL A;  4RXC A;  3QKC A;  5H9D A;  2E8U A;  3M02 A;  2E95 A;  4LFV F;  3S4J A;  1V4H A;  2H8O A;  3PDE A;  2QIS A;  2ZCO A;  3AQB B;  3AQC B;  4P0V A;  2F92 F;  4NFK F;  2Z4V A;  5JV1 F;  2ZY1 A;  1WL2 A;  4JZB A;  3WCM A;  3QQV A;  5DJR F;  5E8H A;  5E8L A;  2PS8 A;  1RQI A;  3WEK A;  4LLS A;  2ZEV A;  3WEJ A;  5IKH A;  4NKF A;  3LVS A;  4KUX A;  3ZCD A;  3MZV A;  3NPK A;  1YHK A;  4KQU A;  3WCB A;  5ILD A;  1YYT A;  4LIX A;  2OA6 A;  3ICN A;  3WJO A;  1HXC A;  1HXA A;  2OGD A;  3LZ9 A;  2F8C F;  4XQS F;  3N45 F;  3BNY A;  3M01 A;  1UBX A;  2E8T A;  3VJD A;  5A0K A;  2RAH A;  3SDT A;  2Z78 A;  4H5D F;  4Q23 A;  5DW7 A;  3EGT A;  1JFA A;  4LZ3 A;  3VJB A;  3ZMB A;  1VG7 A;  4LUU A;  4ZQ8 A;  5A0J A;  3P5P A;  4LA6 A;  4MC0 A;  5ILZ A;  3ICM A;  3WCH A;  2ONH A;  5HNA A;  4LXW A;  1N1B A;  3EZ3 A;  4FJQ A;  5HN8 A;  1N23 A;  3SDR A;  4KWD A;  1UBY A;  4LFE A;  4EA0 A;  3RBM A;  4KVW A;  3SDV A;  3AE0 A;  4LTZ A;  2Q80 A;  3KRO A;  4DWG A;  5B01 A;  3APZ A;  3RYE A;  4DHD A;  3OAB B;  4DWB A;  4NFJ F;  5IKA A;  5IK0 A;  5AHU B;  1YQ7 A;  4JXN A;  4JZX A;  1DGP A;  4N1Z F;  5B0K A;  2Z7H A;  4F6X A;  2O1O A;  2E8X A;  3KRF A;  3EFQ A;  5B00 A;  3IBA A;  4FP4 A;  3ZL6 A;  2E4O A;  2J5C A;  3P41 A;  3KBK A;  2Z7I A;  1YJ4 A;  5HN9 A;  4F6V A;  3CP6 A;  3WE9 A;  5AFX A;  3N0G A;  3TFV A;  2FOR A;  4LA5 A;  4GP2 A;  3TFP A;  3RMG A;  4F62 A;  4P0X A;  3N0F A;  1WL1 A;  3UCA A;  3CKE A;  5EAU A;  3M9U A;  5ILJ A;  5DIQ F;  4LOB A;  4KVI A;  4OKM A;  3WJK A;  3AQ0 A;  5E8K A;  2Q58 A;  1YHL A;  4KPD A;  1V4I A;  3SDQ A;  1YYU A;  4LTV A;  2ZCR A;  4MC3 A;  2OPN A;  3WCI A;  5JA0 F;  4KVD A;  1YYQ A;  1KIY A;  4RNQ A;  4E1E A;  5DGS F;  4EA1 A;  3KRC B;  4RXA A;  3LJI A;  1N24 A;  5ERN A;  1WL3 A;  1YHM A;  1EZF A;  2E92 A;  3N5H F;  4LPG F;  1YV5 A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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