3EHXA

Crystal structure of the catalytic domain of human mmp12 complexed with the inhibitor (r)-2-(biphenyl-4-ylsulfonamido)-4-methylpentanoic acid
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
158
structure length
158
Chain Sequence
GPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Biotin-tagged probes for MMP expression and activation: design, synthesis, and binding properties
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Macrophage metalloelastase
total genus 45
structure length 158
sequence length 158
ec nomenclature ec 3.4.24.65: Macrophage elastase.
pdb deposition date 2008-09-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 3ehxA00
5L7FA 3HY7A 4GQLA 5B5OA 2OW2A 1I1IP 1UMTA 4IN9A 1BM6A 3E8RA 1IACA 4I03A 1MMPA 1S4BP 2W15A 5I43A 1PWQA 1C7KA 2JT6A 3I7IA 2K9CA 3VTGA 2W12A 1QJIA 1XFXA 1GXDA 3ELMA 3TSKA 2O36A 1OMJA 2EROA 1USNA 3BA0A 3LUNA 2DW0A 4GR8A 4JA1A 4A3WA 1XFYA 3CKIA 1SMPA 3DPFA 5BPAA 1BKCA 4GR3A 3B92A 2TCLA 3AIGA 1JJ9A 1XFZA 3B2ZA 1R1JA 1RMZA 1XFWA 1CGEA 3EDGA 1WNIA 3O64A 1H71P 1PWWA 2V4BA 1BUVM 4GUYA 1BZSA 2WO9A 3LUMA 4JIJA 1ZS0A 2OW1A 2O3EA 4ON1A 1FM1A 3F1AA 2QPJA 5D1UA 3B8ZA 2OXZA 5L79A 1G4KA 1SATA 1SU3A 3G5CA 4JPAA 1R1HA 1JAPA 1G9KA 1O0QA 4AYKA 1HFCA 1KUKA 4JP4A 3WV2A 3ZXHA 2W14A 4H76A 2OVXA 1HY7A 3TVCA 1KAPP 4G0DA 1I76A 4L63A 4WF6A 3EDIA 1BKCE 1G12A 2Z2DA 1XUCA 3AYUA 3KMEA 5B5PA 2USNA 4Q1LA 3Q2HA 2DW2A 3DL1A 4FVLA 4L6TA 1RM8A 3ZUKA 4XBHA 1CQRA 5BOYA 1A85A 1OM8A 1IABA 5H8XA 1ND1A 4AUOA 1EUBA 1JKYA 4WKIA 1ZTQA 1HFSA 3KHIA 1UMSA 2MZEA 2SRTA 3MA2A 3HY9A 5D7WA 3RTTA 3DPEA 4PKWA 5D3CA 3KRYA 2HU6A 1O0TA 5I2ZA 1XURA 1B8YA 2OXWA 2POJA 3LIKA 3HDAP 1PWPA 1ZXVA 4J4MA 2JT5A 5LABA 4DF9A 2E2DA 3GBOA 3VI1A 3P24A 1MMQA 1BSWA 1EAKA 3AYKA 1ATLA 4H3XA 1CGFA 3F16A 1FBLA 1QIBA 3LQ0A 4IUWA 3O2XA 3KECA 4IJOA 1J7NA 4H82A 1Y93A 4HMAA 4I35A 3HYGA 1R1IA 4GF1A 3LILA 1CK7A 3TS4A 1C3IA 1YP1A 1JIWP 5I0LA 1GE6A 3WV1A 4FXYP 3DSLA 1CAQA 1JAOA 1Q3AA 2OVZA 5D1SA 2X3AA 1BQQM 1ZP5A 4ILWD 2ERPA 4QKZA 1OS2A 1K7IA 1L6JA 3LEAA 2XS3A 3WV3A 1R55A 4PKTA 2DW1A 1A86A 4AXQA 2CLTA 1HV5A 456CA 3OHLA 2L0RA 1UEAA 1YQYA 1GE5A 1ASTA 1PWUA 2X3CA 1BKCI 3F17A 1SLNA 1CXVA 3LE9A 1JK3A 1BUDA 2CKIA 3HBUP 2JNPA 1AKLA 1JANA 3DWBA 1KBCA 3F19A 3OHOA 3TT4A 3DNGA 5I12A 2OY4A 3NX7A 4H49A 4H30A 1MMRA 830CA 1UTZA 2A8HA 2JSDA 2Y6CA 2ERQA 3HDBA 4H2EA 1KUFA 2OZRA 2WOAA 1BQOA 1DMTA 1ROSA 1GO8P 4G9LA 4H84A 4PKQA 1ZVXA 2RJQA 3SHIA 2AYKA 3LJGA 2W13A 4CTHA 1KUGA 1OM7A 2J83A 3USNA 2FV5A 1D5JA 4PKSA 3LMCA 4XM7A 4XCTA 1IAGA 2AIGP 1AF0A 5JMYA 2MZHA 1QUAA 1IAAA 4ZR5A 1XUDA 2OY2A 4GR0A 3HBVP 3EDHA 2YB9A 1JIZA 3KMCA 1ZXCA 1DTHA 3K7NA 4EFSA 3LKAA 3LGPA 4DPEA 4DV8A 4FXQA 4H1QA 5I3MA 3F15A 2D1NA 4PKUA 1D8MA 5D1TA 1G49A 3KWVC 4HX3A 2X3BA 3F18A 3KEJA 4DD8A 1CIZA 1GO7P 1HTDA 2I47A 2OW9A 2DDYA 3Q2GA 1D7XA 1SLMA 3LIRA 1IADA 966CA 1OS9A 5CUHA 3EHXA 1KUHA 4R3VA 1HOVA 1GKDA 2X7MA 1Y8JA 4WKEA 1YCMA 3L0VA 4XM6A 2YIGA 2MLRA 1GKCA 4XM8A 3UVCA 1JH1A 1JAQA 3KEKA 3ZVSA 1EB6A 2MLSA 4JQGA 3RTSA 1QIAA 1AYKA 5BOTA 3EDZA 2OI0A 1K7GA 4A7BA 2KRJA 1OO9A 2W0DA 2PJTA 2XS4A 4FU4A 4GWMA 3K7LA 2FV9A 1FLSA 1I73A 4PKVA 1G05A 1PWVA 2E3XA 1IAEA 3U1RA 3G42A 5I4OA 3LJTA 2JIHA 3V96B 1XFUA 1MNCA 3EHYA 1YOUA 1BIWA 3LJZA 2RJPA 1K7QA 1GE7A 4WK7A 5CZMA 4WZVA 3LK8A 4GWNA 2Y6DA 3I7GA 2D1OA 1B3DA 5D2BA 3HB2P 5CXAA 3P1VA 2N8RA 1Z3JA 4L19A 2K2GA 1CGLA 3N2UA 2DDFA 1KUIA 1QJJA 1SRPA 2MZIA 1MMBA 3N2VA 2WO8A 1C8TA 1Y0VA 4PKRA 4AIGA 1OM6A 1R54A 3EWJA 2J0TA 1XFVA 1QICA 1D8FA 2OXUA 3L0TA 3LQBA 2OW0A 1UTTA
chains in the Genus database with same CATH superfamily
5L7FA 3HY7A 4GQLA 5B5OA 2OW2A 1I1IP 1UMTA 4IN9A 1BM6A 3E8RA 1IACA 4I03A 1XM5A 1XAXA 1MMPA 1S4BP 2W15A 5I43A 1PWQA 1C7KA 2JT6A 3I7IA 2K9CA 3VTGA 2W12A 1QJIA 2YUFA 1XFXA 1GXDA 3ELMA 3TSKA 2O36A 1OMJA 2EROA 1USNA 3BA0A 3LUNA 2DW0A 4GR8A 4JA1A 4A3WA 1XFYA 3CKIA 1SMPA 3DPFA 5BPAA 1BKCA 4GR3A 3B92A 2TCLA 3AIGA 1JJ9A 1XFZA 3B2ZA 1R1JA 1RMZA 1XFWA 1CGEA 3EDGA 1WNIA 3O64A 1H71P 1PWWA 2V4BA 1BUVM 4GUYA 1BZSA 2WO9A 3LUMA 4JIJA 1ZS0A 2OW1A 2O3EA 4ON1A 1FM1A 3F1AA 2QPJA 5D1UA 3B8ZA 2OXZA 5L79A 1G4KA 1SATA 1SU3A 3G5CA 4JPAA 1R1HA 1JAPA 1G9KA 1O0QA 4AYKA 1HFCA 1KUKA 4JP4A 3WV2A 3ZXHA 2W14A 4H76A 2OVXA 1HY7A 3TVCA 1KAPP 4G0DA 1I76A 4L63A 4WF6A 3EDIA 1BKCE 1G12A 2Z2DA 1XUCA 3AYUA 3KMEA 5B5PA 2USNA 4Q1LA 3Q2HA 2DW2A 3DL1A 4FVLA 4L7AA 4L6TA 1RM8A 3ZUKA 4XBHA 3DTIA 1CQRA 5BOYA 1A85A 1OM8A 1IABA 5H8XA 1ND1A 4AUOA 1EUBA 1JKYA 4WKIA 1ZTQA 1HFSA 3KHIA 1UMSA 1OZ9A 2MZEA 2SRTA 3MA2A 3HY9A 5D7WA 3RTTA 3DPEA 4PKWA 5D3CA 3KRYA 2HU6A 1O0TA 5I2ZA 1XURA 1B8YA 2OXWA 2POJA 3LIKA 3HDAP 1PWPA 1ZXVA 4J4MA 2JT5A 5LABA 4DF9A 2E2DA 3GBOA 3VI1A 3P24A 1MMQA 1BSWA 1EAKA 3AYKA 1ATLA 4H3XA 1CGFA 3F16A 1FBLA 1QIBA 3LQ0A 4IUWA 3O2XA 3KECA 4IJOA 1J7NA 4H82A 1Y93A 4HMAA 4I35A 3HYGA 1R1IA 4GF1A 3LILA 1CK7A 3TS4A 1C3IA 1YP1A 1JIWP 5I0LA 1GE6A 3WV1A 4FXYP 3DSLA 1CAQA 1JAOA 1Q3AA 2OVZA 5D1SA 2X3AA 1BQQM 1ZP5A 4ILWD 2ERPA 4QKZA 1OS2A 1K7IA 1L6JA 3LEAA 1TVIA 2XS3A 3WV3A 1R55A 4PKTA 3DTKA 2DW1A 1A86A 4AXQA 2CLTA 1HV5A 456CA 3OHLA 2L0RA 1UEAA 1YQYA 1GE5A 1ASTA 1PWUA 2X3CA 1BKCI 3F17A 1SLNA 1CXVA 3LE9A 1JK3A 1BUDA 2CKIA 3HBUP 2JNPA 1AKLA 1JANA 3DWBA 1KBCA 3F19A 3OHOA 3TT4A 3DNGA 5I12A 2OY4A 3NX7A 4H49A 4H30A 1MMRA 830CA 1UTZA 2A8HA 2JSDA 2Y6CA 2ERQA 3HDBA 4H2EA 1KUFA 2OZRA 2WOAA 1BQOA 1DMTA 1ROSA 1GO8P 4G9LA 4H84A 4PKQA 1ZVXA 2RJQA 3SHIA 2AYKA 3LJGA 2W13A 4CTHA 1KUGA 1OM7A 2J83A 3USNA 2FV5A 1D5JA 4PKSA 3LMCA 4XM7A 4XCTA 1IAGA 2AIGP 1AF0A 5JMYA 2MZHA 1QUAA 1IAAA 4ZR5A 1XUDA 2OY2A 4GR0A 3HBVP 3EDHA 2YB9A 1JIZA 3KMCA 1ZXCA 1DTHA 3K7NA 4EFSA 3LKAA 3LGPA 4DPEA 4DV8A 4FXQA 4H1QA 5I3MA 3F15A 2D1NA 4PKUA 1D8MA 5D1TA 1G49A 3KWVC 4HX3A 2X3BA 3F18A 3KEJA 4DD8A 1CIZA 1GO7P 1HTDA 2I47A 2OW9A 2DDYA 3Q2GA 1D7XA 1SLMA 3LIRA 1IADA 966CA 1OS9A 5CUHA 3EHXA 1KUHA 4R3VA 1HOVA 1GKDA 2X7MA 1Y8JA 4WKEA 1YCMA 3L0VA 4XM6A 2YIGA 2MLRA 1GKCA 4XM8A 3UVCA 1JH1A 1JAQA 3KEKA 3ZVSA 1EB6A 2MLSA 4JQGA 3RTSA 1QIAA 1AYKA 5BOTA 3EDZA 2OI0A 1K7GA 4A7BA 2KRJA 1OO9A 2W0DA 2PJTA 2XS4A 4FU4A 4GWMA 3K7LA 2FV9A 1FLSA 1I73A 4PKVA 1G05A 1PWVA 2E3XA 1IAEA 3U1RA 3G42A 5I4OA 3LJTA 2JIHA 3V96B 1XFUA 1MNCA 3EHYA 1YOUA 1BIWA 3LJZA 2RJPA 1K7QA 1GE7A 4WK7A 5CZMA 4WZVA 3LK8A 4GWNA 2Y6DA 3I7GA 2D1OA 1B3DA 3DTEA 5D2BA 3HB2P 5CXAA 3P1VA 2N8RA 1Z3JA 4L19A 2K2GA 1CGLA 3N2UA 2DDFA 1KUIA 1QJJA 1SRPA 2MZIA 1MMBA 3N2VA 2WO8A 1C8TA 1Y0VA 4PKRA 4AIGA 1OM6A 1R54A 3EWJA 2J0TA 1XFVA 1QICA 1D8FA 2OXUA 3L0TA 3LQBA 2OW0A 1UTTA
chains in the Genus database with same CATH topology
5L7FA 3HY7A 4GQLA 5B5OA 2OW2A 1I1IP 1UMTA 4IN9A 1BM6A 3E8RA 1IACA 4I03A 1MMPA 1S4BP 2W15A 5I43A 1PWQA 1C7KA 2JT6A 3I7IA 2K9CA 3VTGA 2W12A 1QJIA 2YUFA 1XFXA 1GXDA 3ELMA 3TSKA 2O36A 1OMJA 2EROA 1USNA 3BA0A 3LUNA 2DW0A 4GR8A 4JA1A 4A3WA 1XFYA 3CKIA 1SMPA 3DPFA 5BPAA 1BKCA 4GR3A 3B92A 2TCLA 3AIGA 1JJ9A 1XFZA 3B2ZA 1R1JA 1RMZA 1XFWA 1CGEA 3EDGA 1WNIA 3O64A 1H71P 1PWWA 2V4BA 1BUVM 4GUYA 1BZSA 2WO9A 3LUMA 4JIJA 1ZS0A 2OW1A 2O3EA 4ON1A 1FM1A 3F1AA 2QPJA 5D1UA 3B8ZA 2OXZA 5L79A 1G4KA 1SATA 1SU3A 3G5CA 4JPAA 1R1HA 1JAPA 1G9KA 1O0QA 4AYKA 1HFCA 1KUKA 4JP4A 3WV2A 3ZXHA 2W14A 4H76A 2OVXA 1HY7A 3TVCA 1KAPP 4G0DA 1I76A 4L63A 4WF6A 3EDIA 1BKCE 1G12A 2Z2DA 1XUCA 3AYUA 3KMEA 5B5PA 2USNA 4Q1LA 3Q2HA 2DW2A 3DL1A 4FVLA 4L7AA 4L6TA 1RM8A 3ZUKA 4XBHA 3DTIA 1CQRA 5BOYA 1A85A 1OM8A 1IABA 5H8XA 1ND1A 4AUOA 1EUBA 1JKYA 4WKIA 1ZTQA 1HFSA 3KHIA 1UMSA 2MZEA 2SRTA 3MA2A 3HY9A 5D7WA 3RTTA 3DPEA 4PKWA 5D3CA 3KRYA 2HU6A 1O0TA 5I2ZA 1XURA 1B8YA 2OXWA 2POJA 3LIKA 3HDAP 1PWPA 1ZXVA 4J4MA 2JT5A 5LABA 4DF9A 2E2DA 3GBOA 3VI1A 3P24A 1MMQA 1BSWA 1EAKA 3AYKA 1ATLA 4H3XA 1CGFA 3F16A 1FBLA 1QIBA 3LQ0A 4IUWA 3O2XA 3KECA 4IJOA 1J7NA 4H82A 1Y93A 4HMAA 4I35A 3HYGA 1R1IA 4GF1A 3LILA 1CK7A 3TS4A 1C3IA 1YP1A 1JIWP 5I0LA 1GE6A 3WV1A 4FXYP 3DSLA 1CAQA 1JAOA 1Q3AA 2OVZA 5D1SA 2X3AA 1BQQM 1ZP5A 4ILWD 2ERPA 4QKZA 1OS2A 1K7IA 1L6JA 3LEAA 2XS3A 3WV3A 1R55A 4PKTA 3DTKA 2DW1A 1A86A 4AXQA 2CLTA 1HV5A 456CA 3OHLA 2L0RA 1UEAA 1YQYA 1GE5A 1ASTA 1PWUA 2X3CA 1BKCI 3F17A 1SLNA 1CXVA 3LE9A 1JK3A 1BUDA 2CKIA 3HBUP 2JNPA 1AKLA 1JANA 3DWBA 1KBCA 3F19A 3OHOA 3TT4A 3DNGA 5I12A 2OY4A 3NX7A 4H49A 4H30A 1MMRA 830CA 1UTZA 2A8HA 2JSDA 2Y6CA 2ERQA 3HDBA 4H2EA 1KUFA 2OZRA 2WOAA 1BQOA 1DMTA 1ROSA 1GO8P 4G9LA 4H84A 4PKQA 1ZVXA 2RJQA 3SHIA 2AYKA 3LJGA 2W13A 4CTHA 1KUGA 1OM7A 2J83A 3USNA 2FV5A 1D5JA 4PKSA 3LMCA 4XM7A 4XCTA 1IAGA 2AIGP 1AF0A 5JMYA 2MZHA 1QUAA 1IAAA 4ZR5A 1XUDA 2OY2A 4GR0A 3HBVP 3EDHA 2YB9A 1JIZA 3KMCA 1ZXCA 1DTHA 3K7NA 4EFSA 3LKAA 3LGPA 4DPEA 4DV8A 4FXQA 4H1QA 5I3MA 3F15A 2D1NA 4PKUA 1D8MA 5D1TA 1G49A 3KWVC 4HX3A 2X3BA 3F18A 3KEJA 4DD8A 1CIZA 1GO7P 1HTDA 2I47A 2OW9A 2DDYA 3Q2GA 1D7XA 1SLMA 3LIRA 1IADA 966CA 1OS9A 5CUHA 3EHXA 1KUHA 4R3VA 1HOVA 1GKDA 2X7MA 1Y8JA 4WKEA 1YCMA 3L0VA 4XM6A 2YIGA 2MLRA 1GKCA 4XM8A 3UVCA 1JH1A 1JAQA 3KEKA 3ZVSA 1EB6A 2MLSA 4JQGA 3RTSA 1QIAA 1AYKA 5BOTA 3EDZA 2OI0A 1K7GA 4A7BA 2KRJA 1OO9A 2W0DA 2PJTA 2XS4A 4FU4A 4GWMA 3K7LA 2FV9A 1FLSA 1I73A 4PKVA 1G05A 1PWVA 2E3XA 1IAEA 3U1RA 3G42A 5I4OA 3LJTA 2JIHA 3V96B 1XFUA 1MNCA 3EHYA 1YOUA 1BIWA 3LJZA 2RJPA 1K7QA 1GE7A 4WK7A 5CZMA 4WZVA 3LK8A 4GWNA 2Y6DA 3I7GA 2D1OA 1B3DA 3DTEA 5D2BA 3HB2P 5CXAA 3P1VA 2N8RA 1Z3JA 4L19A 2K2GA 1CGLA 3N2UA 2DDFA 1KUIA 1QJJA 1SRPA 2MZIA 1MMBA 3N2VA 2WO8A 1C8TA 1Y0VA 4PKRA 4AIGA 1OM6A 1R54A 3EWJA 2J0TA 1XFVA 1QICA 1D8FA 2OXUA 3L0TA 3LQBA 2OW0A 1UTTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5L7F A;  3HY7 A;  4GQL A;  5B5O A;  2OW2 A;  1I1I P;  1UMT A;  4IN9 A;  1BM6 A;  3E8R A;  1IAC A;  4I03 A;  1MMP A;  1S4B P;  2W15 A;  5I43 A;  1PWQ A;  1C7K A;  2JT6 A;  3I7I A;  2K9C A;  3VTG A;  2W12 A;  1QJI A;  1XFX A;  1GXD A;  3ELM A;  3TSK A;  2O36 A;  1OMJ A;  2ERO A;  1USN A;  3BA0 A;  3LUN A;  2DW0 A;  4GR8 A;  4JA1 A;  4A3W A;  1XFY A;  3CKI A;  1SMP A;  3DPF A;  5BPA A;  1BKC A;  4GR3 A;  3B92 A;  2TCL A;  3AIG A;  1JJ9 A;  1XFZ A;  3B2Z A;  1R1J A;  1RMZ A;  1XFW A;  1CGE A;  3EDG A;  1WNI A;  3O64 A;  1H71 P;  1PWW A;  2V4B A;  1BUV M;  4GUY A;  1BZS A;  2WO9 A;  3LUM A;  4JIJ A;  1ZS0 A;  2OW1 A;  2O3E A;  4ON1 A;  1FM1 A;  3F1A A;  2QPJ A;  5D1U A;  3B8Z A;  2OXZ A;  5L79 A;  1G4K A;  1SAT A;  1SU3 A;  3G5C A;  4JPA A;  1R1H A;  1JAP A;  1G9K A;  1O0Q A;  4AYK A;  1HFC A;  1KUK A;  4JP4 A;  3WV2 A;  3ZXH A;  2W14 A;  4H76 A;  2OVX A;  1HY7 A;  3TVC A;  1KAP P;  4G0D A;  1I76 A;  4L63 A;  4WF6 A;  3EDI A;  1BKC E;  1G12 A;  2Z2D A;  1XUC A;  3AYU A;  3KME A;  5B5P A;  2USN A;  4Q1L A;  3Q2H A;  2DW2 A;  3DL1 A;  4FVL A;  4L6T A;  1RM8 A;  3ZUK A;  4XBH A;  1CQR A;  5BOY A;  1A85 A;  1OM8 A;  1IAB A;  5H8X A;  1ND1 A;  4AUO A;  1EUB A;  1JKY A;  4WKI A;  1ZTQ A;  1HFS A;  3KHI A;  1UMS A;  2MZE A;  2SRT A;  3MA2 A;  3HY9 A;  5D7W A;  3RTT A;  3DPE A;  4PKW A;  5D3C A;  3KRY A;  2HU6 A;  1O0T A;  5I2Z A;  1XUR A;  1B8Y A;  2OXW A;  2POJ A;  3LIK A;  3HDA P;  1PWP A;  1ZXV A;  4J4M A;  2JT5 A;  5LAB A;  4DF9 A;  2E2D A;  3GBO A;  3VI1 A;  3P24 A;  1MMQ A;  1BSW A;  1EAK A;  3AYK A;  1ATL A;  4H3X A;  1CGF A;  3F16 A;  1FBL A;  1QIB A;  3LQ0 A;  4IUW A;  3O2X A;  3KEC A;  4IJO A;  1J7N A;  4H82 A;  1Y93 A;  4HMA A;  4I35 A;  3HYG A;  1R1I A;  4GF1 A;  3LIL A;  1CK7 A;  3TS4 A;  1C3I A;  1YP1 A;  1JIW P;  5I0L A;  1GE6 A;  3WV1 A;  4FXY P;  3DSL A;  1CAQ A;  1JAO A;  1Q3A A;  2OVZ A;  5D1S A;  2X3A A;  1BQQ M;  1ZP5 A;  4ILW D;  2ERP A;  4QKZ A;  1OS2 A;  1K7I A;  1L6J A;  3LEA A;  2XS3 A;  3WV3 A;  1R55 A;  4PKT A;  2DW1 A;  1A86 A;  4AXQ A;  2CLT A;  1HV5 A;  456C A;  3OHL A;  2L0R A;  1UEA A;  1YQY A;  1GE5 A;  1AST A;  1PWU A;  2X3C A;  1BKC I;  3F17 A;  1SLN A;  1CXV A;  3LE9 A;  1JK3 A;  1BUD A;  2CKI A;  3HBU P;  2JNP A;  1AKL A;  1JAN A;  3DWB A;  1KBC A;  3F19 A;  3OHO A;  3TT4 A;  3DNG A;  5I12 A;  2OY4 A;  3NX7 A;  4H49 A;  4H30 A;  1MMR A;  830C A;  1UTZ A;  2A8H A;  2JSD A;  2Y6C A;  2ERQ A;  3HDB A;  4H2E A;  1KUF A;  2OZR A;  2WOA A;  1BQO A;  1DMT A;  1ROS A;  1GO8 P;  4G9L A;  4H84 A;  4PKQ A;  1ZVX A;  2RJQ A;  3SHI A;  2AYK A;  3LJG A;  2W13 A;  4CTH A;  1KUG A;  1OM7 A;  2J83 A;  3USN A;  2FV5 A;  1D5J A;  4PKS A;  3LMC A;  4XM7 A;  4XCT A;  1IAG A;  2AIG P;  1AF0 A;  5JMY A;  2MZH A;  1QUA A;  1IAA A;  4ZR5 A;  1XUD A;  2OY2 A;  4GR0 A;  3HBV P;  3EDH A;  2YB9 A;  1JIZ A;  3KMC A;  1ZXC A;  1DTH A;  3K7N A;  4EFS A;  3LKA A;  3LGP A;  4DPE A;  4DV8 A;  4FXQ A;  4H1Q A;  5I3M A;  3F15 A;  2D1N A;  4PKU A;  1D8M A;  5D1T A;  1G49 A;  3KWV C;  4HX3 A;  2X3B A;  3F18 A;  3KEJ A;  4DD8 A;  1CIZ A;  1GO7 P;  1HTD A;  2I47 A;  2OW9 A;  2DDY A;  3Q2G A;  1D7X A;  1SLM A;  3LIR A;  1IAD A;  966C A;  1OS9 A;  5CUH A;  3EHX A;  1KUH A;  4R3V A;  1HOV A;  1GKD A;  2X7M A;  1Y8J A;  4WKE A;  1YCM A;  3L0V A;  4XM6 A;  2YIG A;  2MLR A;  1GKC A;  4XM8 A;  3UVC A;  1JH1 A;  1JAQ A;  3KEK A;  3ZVS A;  1EB6 A;  2MLS A;  4JQG A;  3RTS A;  1QIA A;  1AYK A;  5BOT A;  3EDZ A;  2OI0 A;  1K7G A;  4A7B A;  2KRJ A;  1OO9 A;  2W0D A;  2PJT A;  2XS4 A;  4FU4 A;  4GWM A;  3K7L A;  2FV9 A;  1FLS A;  1I73 A;  4PKV A;  1G05 A;  1PWV A;  2E3X A;  1IAE A;  3U1R A;  3G42 A;  5I4O A;  3LJT A;  2JIH A;  3V96 B;  1XFU A;  1MNC A;  3EHY A;  1YOU A;  1BIW A;  3LJZ A;  2RJP A;  1K7Q A;  1GE7 A;  4WK7 A;  5CZM A;  4WZV A;  3LK8 A;  4GWN A;  2Y6D A;  3I7G A;  2D1O A;  1B3D A;  5D2B A;  3HB2 P;  5CXA A;  3P1V A;  2N8R A;  1Z3J A;  4L19 A;  2K2G A;  1CGL A;  3N2U A;  2DDF A;  1KUI A;  1QJJ A;  1SRP A;  2MZI A;  1MMB A;  3N2V A;  2WO8 A;  1C8T A;  1Y0V A;  4PKR A;  4AIG A;  1OM6 A;  1R54 A;  3EWJ A;  2J0T A;  1XFV A;  1QIC A;  1D8F A;  2OXU A;  3L0T A;  3LQB A;  2OW0 A;  1UTT A; 
#chains in the Genus database with same CATH topology
 5L7F A;  3HY7 A;  4GQL A;  5B5O A;  2OW2 A;  1I1I P;  1UMT A;  4IN9 A;  1BM6 A;  3E8R A;  1IAC A;  4I03 A;  1XM5 A;  1XAX A;  1MMP A;  1S4B P;  2W15 A;  5I43 A;  1PWQ A;  1C7K A;  2JT6 A;  3I7I A;  2K9C A;  3VTG A;  2W12 A;  1QJI A;  2YUF A;  1XFX A;  1GXD A;  3ELM A;  3TSK A;  2O36 A;  1OMJ A;  2ERO A;  1USN A;  3BA0 A;  3LUN A;  2DW0 A;  4GR8 A;  4JA1 A;  4A3W A;  1XFY A;  3CKI A;  1SMP A;  3DPF A;  5BPA A;  1BKC A;  4GR3 A;  3B92 A;  2TCL A;  3AIG A;  1JJ9 A;  1XFZ A;  3B2Z A;  1R1J A;  1RMZ A;  1XFW A;  1CGE A;  3EDG A;  1WNI A;  3O64 A;  1H71 P;  1PWW A;  2V4B A;  1BUV M;  4GUY A;  1BZS A;  2WO9 A;  3LUM A;  4JIJ A;  1ZS0 A;  2OW1 A;  2O3E A;  4ON1 A;  1FM1 A;  3F1A A;  2QPJ A;  5D1U A;  3B8Z A;  2OXZ A;  5L79 A;  1G4K A;  1SAT A;  1SU3 A;  3G5C A;  4JPA A;  1R1H A;  1JAP A;  1G9K A;  1O0Q A;  4AYK A;  1HFC A;  1KUK A;  4JP4 A;  3WV2 A;  3ZXH A;  2W14 A;  4H76 A;  2OVX A;  1HY7 A;  3TVC A;  1KAP P;  4G0D A;  1I76 A;  4L63 A;  4WF6 A;  3EDI A;  1BKC E;  1G12 A;  2Z2D A;  1XUC A;  3AYU A;  3KME A;  5B5P A;  2USN A;  4Q1L A;  3Q2H A;  2DW2 A;  3DL1 A;  4FVL A;  4L7A A;  4L6T A;  1RM8 A;  3ZUK A;  4XBH A;  3DTI A;  1CQR A;  5BOY A;  1A85 A;  1OM8 A;  1IAB A;  5H8X A;  1ND1 A;  4AUO A;  1EUB A;  1JKY A;  4WKI A;  1ZTQ A;  1HFS A;  3KHI A;  1UMS A;  1OZ9 A;  2MZE A;  2SRT A;  3MA2 A;  3HY9 A;  5D7W A;  3RTT A;  3DPE A;  4PKW A;  5D3C A;  3KRY A;  2HU6 A;  1O0T A;  5I2Z A;  1XUR A;  1B8Y A;  2OXW A;  2POJ A;  3LIK A;  3HDA P;  1PWP A;  1ZXV A;  4J4M A;  2JT5 A;  5LAB A;  4DF9 A;  2E2D A;  3GBO A;  3VI1 A;  3P24 A;  1MMQ A;  1BSW A;  1EAK A;  3AYK A;  1ATL A;  4H3X A;  1CGF A;  3F16 A;  1FBL A;  1QIB A;  3LQ0 A;  4IUW A;  3O2X A;  3KEC A;  4IJO A;  1J7N A;  4H82 A;  1Y93 A;  4HMA A;  4I35 A;  3HYG A;  1R1I A;  4GF1 A;  3LIL A;  1CK7 A;  3TS4 A;  1C3I A;  1YP1 A;  1JIW P;  5I0L A;  1GE6 A;  3WV1 A;  4FXY P;  3DSL A;  1CAQ A;  1JAO A;  1Q3A A;  2OVZ A;  5D1S A;  2X3A A;  1BQQ M;  1ZP5 A;  4ILW D;  2ERP A;  4QKZ A;  1OS2 A;  1K7I A;  1L6J A;  3LEA A;  1TVI A;  2XS3 A;  3WV3 A;  1R55 A;  4PKT A;  3DTK A;  2DW1 A;  1A86 A;  4AXQ A;  2CLT A;  1HV5 A;  456C A;  3OHL A;  2L0R A;  1UEA A;  1YQY A;  1GE5 A;  1AST A;  1PWU A;  2X3C A;  1BKC I;  3F17 A;  1SLN A;  1CXV A;  3LE9 A;  1JK3 A;  1BUD A;  2CKI A;  3HBU P;  2JNP A;  1AKL A;  1JAN A;  3DWB A;  1KBC A;  3F19 A;  3OHO A;  3TT4 A;  3DNG A;  5I12 A;  2OY4 A;  3NX7 A;  4H49 A;  4H30 A;  1MMR A;  830C A;  1UTZ A;  2A8H A;  2JSD A;  2Y6C A;  2ERQ A;  3HDB A;  4H2E A;  1KUF A;  2OZR A;  2WOA A;  1BQO A;  1DMT A;  1ROS A;  1GO8 P;  4G9L A;  4H84 A;  4PKQ A;  1ZVX A;  2RJQ A;  3SHI A;  2AYK A;  3LJG A;  2W13 A;  4CTH A;  1KUG A;  1OM7 A;  2J83 A;  3USN A;  2FV5 A;  1D5J A;  4PKS A;  3LMC A;  4XM7 A;  4XCT A;  1IAG A;  2AIG P;  1AF0 A;  5JMY A;  2MZH A;  1QUA A;  1IAA A;  4ZR5 A;  1XUD A;  2OY2 A;  4GR0 A;  3HBV P;  3EDH A;  2YB9 A;  1JIZ A;  3KMC A;  1ZXC A;  1DTH A;  3K7N A;  4EFS A;  3LKA A;  3LGP A;  4DPE A;  4DV8 A;  4FXQ A;  4H1Q A;  5I3M A;  3F15 A;  2D1N A;  4PKU A;  1D8M A;  5D1T A;  1G49 A;  3KWV C;  4HX3 A;  2X3B A;  3F18 A;  3KEJ A;  4DD8 A;  1CIZ A;  1GO7 P;  1HTD A;  2I47 A;  2OW9 A;  2DDY A;  3Q2G A;  1D7X A;  1SLM A;  3LIR A;  1IAD A;  966C A;  1OS9 A;  5CUH A;  3EHX A;  1KUH A;  4R3V A;  1HOV A;  1GKD A;  2X7M A;  1Y8J A;  4WKE A;  1YCM A;  3L0V A;  4XM6 A;  2YIG A;  2MLR A;  1GKC A;  4XM8 A;  3UVC A;  1JH1 A;  1JAQ A;  3KEK A;  3ZVS A;  1EB6 A;  2MLS A;  4JQG A;  3RTS A;  1QIA A;  1AYK A;  5BOT A;  3EDZ A;  2OI0 A;  1K7G A;  4A7B A;  2KRJ A;  1OO9 A;  2W0D A;  2PJT A;  2XS4 A;  4FU4 A;  4GWM A;  3K7L A;  2FV9 A;  1FLS A;  1I73 A;  4PKV A;  1G05 A;  1PWV A;  2E3X A;  1IAE A;  3U1R A;  3G42 A;  5I4O A;  3LJT A;  2JIH A;  3V96 B;  1XFU A;  1MNC A;  3EHY A;  1YOU A;  1BIW A;  3LJZ A;  2RJP A;  1K7Q A;  1GE7 A;  4WK7 A;  5CZM A;  4WZV A;  3LK8 A;  4GWN A;  2Y6D A;  3I7G A;  2D1O A;  1B3D A;  3DTE A;  5D2B A;  3HB2 P;  5CXA A;  3P1V A;  2N8R A;  1Z3J A;  4L19 A;  2K2G A;  1CGL A;  3N2U A;  2DDF A;  1KUI A;  1QJJ A;  1SRP A;  2MZI A;  1MMB A;  3N2V A;  2WO8 A;  1C8T A;  1Y0V A;  4PKR A;  4AIG A;  1OM6 A;  1R54 A;  3EWJ A;  2J0T A;  1XFV A;  1QIC A;  1D8F A;  2OXU A;  3L0T A;  3LQB A;  2OW0 A;  1UTT A; 
#chains in the Genus database with same CATH homology
 5L7F A;  3HY7 A;  4GQL A;  5B5O A;  2OW2 A;  1I1I P;  1UMT A;  4IN9 A;  1BM6 A;  3E8R A;  1IAC A;  4I03 A;  1MMP A;  1S4B P;  2W15 A;  5I43 A;  1PWQ A;  1C7K A;  2JT6 A;  3I7I A;  2K9C A;  3VTG A;  2W12 A;  1QJI A;  2YUF A;  1XFX A;  1GXD A;  3ELM A;  3TSK A;  2O36 A;  1OMJ A;  2ERO A;  1USN A;  3BA0 A;  3LUN A;  2DW0 A;  4GR8 A;  4JA1 A;  4A3W A;  1XFY A;  3CKI A;  1SMP A;  3DPF A;  5BPA A;  1BKC A;  4GR3 A;  3B92 A;  2TCL A;  3AIG A;  1JJ9 A;  1XFZ A;  3B2Z A;  1R1J A;  1RMZ A;  1XFW A;  1CGE A;  3EDG A;  1WNI A;  3O64 A;  1H71 P;  1PWW A;  2V4B A;  1BUV M;  4GUY A;  1BZS A;  2WO9 A;  3LUM A;  4JIJ A;  1ZS0 A;  2OW1 A;  2O3E A;  4ON1 A;  1FM1 A;  3F1A A;  2QPJ A;  5D1U A;  3B8Z A;  2OXZ A;  5L79 A;  1G4K A;  1SAT A;  1SU3 A;  3G5C A;  4JPA A;  1R1H A;  1JAP A;  1G9K A;  1O0Q A;  4AYK A;  1HFC A;  1KUK A;  4JP4 A;  3WV2 A;  3ZXH A;  2W14 A;  4H76 A;  2OVX A;  1HY7 A;  3TVC A;  1KAP P;  4G0D A;  1I76 A;  4L63 A;  4WF6 A;  3EDI A;  1BKC E;  1G12 A;  2Z2D A;  1XUC A;  3AYU A;  3KME A;  5B5P A;  2USN A;  4Q1L A;  3Q2H A;  2DW2 A;  3DL1 A;  4FVL A;  4L7A A;  4L6T A;  1RM8 A;  3ZUK A;  4XBH A;  3DTI A;  1CQR A;  5BOY A;  1A85 A;  1OM8 A;  1IAB A;  5H8X A;  1ND1 A;  4AUO A;  1EUB A;  1JKY A;  4WKI A;  1ZTQ A;  1HFS A;  3KHI A;  1UMS A;  2MZE A;  2SRT A;  3MA2 A;  3HY9 A;  5D7W A;  3RTT A;  3DPE A;  4PKW A;  5D3C A;  3KRY A;  2HU6 A;  1O0T A;  5I2Z A;  1XUR A;  1B8Y A;  2OXW A;  2POJ A;  3LIK A;  3HDA P;  1PWP A;  1ZXV A;  4J4M A;  2JT5 A;  5LAB A;  4DF9 A;  2E2D A;  3GBO A;  3VI1 A;  3P24 A;  1MMQ A;  1BSW A;  1EAK A;  3AYK A;  1ATL A;  4H3X A;  1CGF A;  3F16 A;  1FBL A;  1QIB A;  3LQ0 A;  4IUW A;  3O2X A;  3KEC A;  4IJO A;  1J7N A;  4H82 A;  1Y93 A;  4HMA A;  4I35 A;  3HYG A;  1R1I A;  4GF1 A;  3LIL A;  1CK7 A;  3TS4 A;  1C3I A;  1YP1 A;  1JIW P;  5I0L A;  1GE6 A;  3WV1 A;  4FXY P;  3DSL A;  1CAQ A;  1JAO A;  1Q3A A;  2OVZ A;  5D1S A;  2X3A A;  1BQQ M;  1ZP5 A;  4ILW D;  2ERP A;  4QKZ A;  1OS2 A;  1K7I A;  1L6J A;  3LEA A;  2XS3 A;  3WV3 A;  1R55 A;  4PKT A;  3DTK A;  2DW1 A;  1A86 A;  4AXQ A;  2CLT A;  1HV5 A;  456C A;  3OHL A;  2L0R A;  1UEA A;  1YQY A;  1GE5 A;  1AST A;  1PWU A;  2X3C A;  1BKC I;  3F17 A;  1SLN A;  1CXV A;  3LE9 A;  1JK3 A;  1BUD A;  2CKI A;  3HBU P;  2JNP A;  1AKL A;  1JAN A;  3DWB A;  1KBC A;  3F19 A;  3OHO A;  3TT4 A;  3DNG A;  5I12 A;  2OY4 A;  3NX7 A;  4H49 A;  4H30 A;  1MMR A;  830C A;  1UTZ A;  2A8H A;  2JSD A;  2Y6C A;  2ERQ A;  3HDB A;  4H2E A;  1KUF A;  2OZR A;  2WOA A;  1BQO A;  1DMT A;  1ROS A;  1GO8 P;  4G9L A;  4H84 A;  4PKQ A;  1ZVX A;  2RJQ A;  3SHI A;  2AYK A;  3LJG A;  2W13 A;  4CTH A;  1KUG A;  1OM7 A;  2J83 A;  3USN A;  2FV5 A;  1D5J A;  4PKS A;  3LMC A;  4XM7 A;  4XCT A;  1IAG A;  2AIG P;  1AF0 A;  5JMY A;  2MZH A;  1QUA A;  1IAA A;  4ZR5 A;  1XUD A;  2OY2 A;  4GR0 A;  3HBV P;  3EDH A;  2YB9 A;  1JIZ A;  3KMC A;  1ZXC A;  1DTH A;  3K7N A;  4EFS A;  3LKA A;  3LGP A;  4DPE A;  4DV8 A;  4FXQ A;  4H1Q A;  5I3M A;  3F15 A;  2D1N A;  4PKU A;  1D8M A;  5D1T A;  1G49 A;  3KWV C;  4HX3 A;  2X3B A;  3F18 A;  3KEJ A;  4DD8 A;  1CIZ A;  1GO7 P;  1HTD A;  2I47 A;  2OW9 A;  2DDY A;  3Q2G A;  1D7X A;  1SLM A;  3LIR A;  1IAD A;  966C A;  1OS9 A;  5CUH A;  3EHX A;  1KUH A;  4R3V A;  1HOV A;  1GKD A;  2X7M A;  1Y8J A;  4WKE A;  1YCM A;  3L0V A;  4XM6 A;  2YIG A;  2MLR A;  1GKC A;  4XM8 A;  3UVC A;  1JH1 A;  1JAQ A;  3KEK A;  3ZVS A;  1EB6 A;  2MLS A;  4JQG A;  3RTS A;  1QIA A;  1AYK A;  5BOT A;  3EDZ A;  2OI0 A;  1K7G A;  4A7B A;  2KRJ A;  1OO9 A;  2W0D A;  2PJT A;  2XS4 A;  4FU4 A;  4GWM A;  3K7L A;  2FV9 A;  1FLS A;  1I73 A;  4PKV A;  1G05 A;  1PWV A;  2E3X A;  1IAE A;  3U1R A;  3G42 A;  5I4O A;  3LJT A;  2JIH A;  3V96 B;  1XFU A;  1MNC A;  3EHY A;  1YOU A;  1BIW A;  3LJZ A;  2RJP A;  1K7Q A;  1GE7 A;  4WK7 A;  5CZM A;  4WZV A;  3LK8 A;  4GWN A;  2Y6D A;  3I7G A;  2D1O A;  1B3D A;  3DTE A;  5D2B A;  3HB2 P;  5CXA A;  3P1V A;  2N8R A;  1Z3J A;  4L19 A;  2K2G A;  1CGL A;  3N2U A;  2DDF A;  1KUI A;  1QJJ A;  1SRP A;  2MZI A;  1MMB A;  3N2V A;  2WO8 A;  1C8T A;  1Y0V A;  4PKR A;  4AIG A;  1OM6 A;  1R54 A;  3EWJ A;  2J0T A;  1XFV A;  1QIC A;  1D8F A;  2OXU A;  3L0T A;  3LQB A;  2OW0 A;  1UTT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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