3EO2A

Crystal structure of the rhogef domain of human neuroepithelial cell-transforming gene 1 protein
Total Genus 75
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
75
sequence length
187
structure length
187
Chain Sequence
b'LTTREIRRQEAIYEMSRGEQDLIEDLKLARKAYHDPMLKLSIMSEEELTHIFGDLDSYIPLHEDLLTRIGEATKPDGTVEQIGHILVSWLPRLNAYRGYCSNQLAAKALLDQKKQDPRVQDFLQRCLESPFSRKLDLWSFLDIPRSRLVKYPLLLKEILKHTPKEHPDVQLLEDAILIIQGVLSDIN'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Neuroepithelial cell-transforming gene 1 protein
publication title Crystal structure of the RhoGEF domain of human neuroepithelial cell-transforming gene 1 protein
rcsb
source organism Homo sapiens
molecule tags Splicing
total genus 75
structure length 187
sequence length 187
ec nomenclature
pdb deposition date 2008-09-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00621 RhoGEF RhoGEF domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.900.10 Mainly Alpha Up-down Bundle Dbl Homology Domain; Chain A Dbl homology (DH) domain 3eo2A00
1NTYA 1TXDA 2NZ8B 4GZUA 1FOEA 3ODXA 4MT7A 3T06A 5FI0A 3QBVB 4D0NB 1KZGA 2PZ1A 1XD4A 3JV3A 2KR9A 5JHGA 3KSYA 2DFKA 3KZ1A 5FI1A 3GF9A 1X86A 3KY9A 1LB1A 3MPXA 1KZ7A 4GOUA 1KI1B 1XCGA 4GYVA 3ODOA 1DBHA 3P6AA 2Z0QA 2DX1A 4D0OA 5JHHA 2RGNB 1F5XA 3EO2A 3ODWA 3BJIA 1BY1A 2VRWB 4YONA 1RJ2A
chains in the Genus database with same CATH superfamily
1NTYA 1TXDA 2NZ8B 4GZUA 1FOEA 3ODXA 4MT7A 3T06A 5FI0A 3QBVB 4D0NB 1KZGA 2PZ1A 1XD4A 3JV3A 2KR9A 5JHGA 3KSYA 2DFKA 3KZ1A 5FI1A 3GF9A 1X86A 3KY9A 1LB1A 3MPXA 1KZ7A 4GOUA 1KI1B 1XCGA 4GYVA 3ODOA 1DBHA 3P6AA 2Z0QA 2DX1A 4D0OA 5JHHA 2RGNB 1F5XA 3EO2A 3ODWA 3BJIA 1BY1A 2VRWB 4YONA 1RJ2A
chains in the Genus database with same CATH topology
1NTYA 1TXDA 2NZ8B 4GZUA 1FOEA 3ODXA 4MT7A 3T06A 5FI0A 3QBVB 4D0NB 1KZGA 2PZ1A 1XD4A 3JV3A 2KR9A 5JHGA 3KSYA 2DFKA 3KZ1A 5FI1A 3GF9A 1X86A 3KY9A 1LB1A 3MPXA 1KZ7A 4GOUA 1KI1B 1XCGA 4GYVA 3ODOA 1DBHA 3P6AA 2Z0QA 2DX1A 4D0OA 5JHHA 2RGNB 1F5XA 3EO2A 3ODWA 3BJIA 1BY1A 2VRWB 4YONA 1RJ2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1NTY A;  1TXD A;  2NZ8 B;  4GZU A;  1FOE A;  3ODX A;  4MT7 A;  3T06 A;  5FI0 A;  3QBV B;  4D0N B;  1KZG A;  2PZ1 A;  1XD4 A;  3JV3 A;  2KR9 A;  5JHG A;  3KSY A;  2DFK A;  3KZ1 A;  5FI1 A;  3GF9 A;  1X86 A;  3KY9 A;  1LB1 A;  3MPX A;  1KZ7 A;  4GOU A;  1KI1 B;  1XCG A;  4GYV A;  3ODO A;  1DBH A;  3P6A A;  2Z0Q A;  2DX1 A;  4D0O A;  5JHH A;  2RGN B;  1F5X A;  3EO2 A;  3ODW A;  3BJI A;  1BY1 A;  2VRW B;  4YON A;  1RJ2 A; 
#chains in the Genus database with same CATH topology
 1NTY A;  1TXD A;  2NZ8 B;  4GZU A;  1FOE A;  3ODX A;  4MT7 A;  3T06 A;  5FI0 A;  3QBV B;  4D0N B;  1KZG A;  2PZ1 A;  1XD4 A;  3JV3 A;  2KR9 A;  5JHG A;  3KSY A;  2DFK A;  3KZ1 A;  5FI1 A;  3GF9 A;  1X86 A;  3KY9 A;  1LB1 A;  3MPX A;  1KZ7 A;  4GOU A;  1KI1 B;  1XCG A;  4GYV A;  3ODO A;  1DBH A;  3P6A A;  2Z0Q A;  2DX1 A;  4D0O A;  5JHH A;  2RGN B;  1F5X A;  3EO2 A;  3ODW A;  3BJI A;  1BY1 A;  2VRW B;  4YON A;  1RJ2 A; 
#chains in the Genus database with same CATH homology
 1NTY A;  1TXD A;  2NZ8 B;  4GZU A;  1FOE A;  3ODX A;  4MT7 A;  3T06 A;  5FI0 A;  3QBV B;  4D0N B;  1KZG A;  2PZ1 A;  1XD4 A;  3JV3 A;  2KR9 A;  5JHG A;  3KSY A;  2DFK A;  3KZ1 A;  5FI1 A;  3GF9 A;  1X86 A;  3KY9 A;  1LB1 A;  3MPX A;  1KZ7 A;  4GOU A;  1KI1 B;  1XCG A;  4GYV A;  3ODO A;  1DBH A;  3P6A A;  2Z0Q A;  2DX1 A;  4D0O A;  5JHH A;  2RGN B;  1F5X A;  3EO2 A;  3ODW A;  3BJI A;  1BY1 A;  2VRW B;  4YON A;  1RJ2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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