3EO2A

Crystal structure of the rhogef domain of human neuroepithelial cell-transforming gene 1 protein
Total Genus 75
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
75
sequence length
187
structure length
187
Chain Sequence
LTTREIRRQEAIYEMSRGEQDLIEDLKLARKAYHDPMLKLSIMSEEELTHIFGDLDSYIPLHEDLLTRIGEATKPDGTVEQIGHILVSWLPRLNAYRGYCSNQLAAKALLDQKKQDPRVQDFLQRCLESPFSRKLDLWSFLDIPRSRLVKYPLLLKEILKHTPKEHPDVQLLEDAILIIQGVLSDIN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Neuroepithelial cell-transforming gene 1 protein
publication title Crystal structure of the RhoGEF domain of human neuroepithelial cell-transforming gene 1 protein
rcsb
source organism Homo sapiens
molecule tags Splicing
total genus 75
structure length 187
sequence length 187
ec nomenclature
pdb deposition date 2008-09-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00621 RhoGEF RhoGEF domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.900.10 Mainly Alpha Up-down Bundle Dbl Homology Domain; Chain A Dbl homology (DH) domain 3eo2A00
4D0NB 1KI1B 4GOUA 3ODXA 1XCGA 3GF9A 3ODOA 4YONA 3EO2A 1BY1A 2NZ8B 1KZGA 3QBVB 5JHHA 2PZ1A 4GZUA 4GYVA 2Z0QA 1TXDA 5FI0A 2VRWB 3ODWA 1XD4A 1RJ2A 1DBHA 1LB1A 5JHGA 1NTYA 2RGNB 3BJIA 3P6AA 4D0OA 3MPXA 2KR9A 3KY9A 1X86A 1KZ7A 2DFKA 1FOEA 1F5XA 3KZ1A 3KSYA 3T06A 5FI1A 4MT7A 3JV3A 2DX1A
chains in the Genus database with same CATH superfamily
4D0NB 1KI1B 4GOUA 3ODXA 1XCGA 3GF9A 3ODOA 4YONA 3EO2A 1BY1A 2NZ8B 1KZGA 3QBVB 5JHHA 2PZ1A 4GZUA 4GYVA 2Z0QA 1TXDA 5FI0A 2VRWB 3ODWA 1XD4A 1RJ2A 1DBHA 1LB1A 5JHGA 1NTYA 2RGNB 3BJIA 3P6AA 4D0OA 3MPXA 2KR9A 3KY9A 1X86A 1KZ7A 2DFKA 1FOEA 1F5XA 3KZ1A 3KSYA 3T06A 5FI1A 4MT7A 3JV3A 2DX1A
chains in the Genus database with same CATH topology
4D0NB 1KI1B 4GOUA 3ODXA 1XCGA 3GF9A 3ODOA 4YONA 3EO2A 1BY1A 2NZ8B 1KZGA 3QBVB 5JHHA 2PZ1A 4GZUA 4GYVA 2Z0QA 1TXDA 5FI0A 2VRWB 3ODWA 1XD4A 1RJ2A 1DBHA 1LB1A 5JHGA 1NTYA 2RGNB 3BJIA 3P6AA 4D0OA 3MPXA 2KR9A 3KY9A 1X86A 1KZ7A 2DFKA 1FOEA 1F5XA 3KZ1A 3KSYA 3T06A 5FI1A 4MT7A 3JV3A 2DX1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4D0N B;  1KI1 B;  4GOU A;  3ODX A;  1XCG A;  3GF9 A;  3ODO A;  4YON A;  3EO2 A;  1BY1 A;  2NZ8 B;  1KZG A;  3QBV B;  5JHH A;  2PZ1 A;  4GZU A;  4GYV A;  2Z0Q A;  1TXD A;  5FI0 A;  2VRW B;  3ODW A;  1XD4 A;  1RJ2 A;  1DBH A;  1LB1 A;  5JHG A;  1NTY A;  2RGN B;  3BJI A;  3P6A A;  4D0O A;  3MPX A;  2KR9 A;  3KY9 A;  1X86 A;  1KZ7 A;  2DFK A;  1FOE A;  1F5X A;  3KZ1 A;  3KSY A;  3T06 A;  5FI1 A;  4MT7 A;  3JV3 A;  2DX1 A; 
#chains in the Genus database with same CATH topology
 4D0N B;  1KI1 B;  4GOU A;  3ODX A;  1XCG A;  3GF9 A;  3ODO A;  4YON A;  3EO2 A;  1BY1 A;  2NZ8 B;  1KZG A;  3QBV B;  5JHH A;  2PZ1 A;  4GZU A;  4GYV A;  2Z0Q A;  1TXD A;  5FI0 A;  2VRW B;  3ODW A;  1XD4 A;  1RJ2 A;  1DBH A;  1LB1 A;  5JHG A;  1NTY A;  2RGN B;  3BJI A;  3P6A A;  4D0O A;  3MPX A;  2KR9 A;  3KY9 A;  1X86 A;  1KZ7 A;  2DFK A;  1FOE A;  1F5X A;  3KZ1 A;  3KSY A;  3T06 A;  5FI1 A;  4MT7 A;  3JV3 A;  2DX1 A; 
#chains in the Genus database with same CATH homology
 4D0N B;  1KI1 B;  4GOU A;  3ODX A;  1XCG A;  3GF9 A;  3ODO A;  4YON A;  3EO2 A;  1BY1 A;  2NZ8 B;  1KZG A;  3QBV B;  5JHH A;  2PZ1 A;  4GZU A;  4GYV A;  2Z0Q A;  1TXD A;  5FI0 A;  2VRW B;  3ODW A;  1XD4 A;  1RJ2 A;  1DBH A;  1LB1 A;  5JHG A;  1NTY A;  2RGN B;  3BJI A;  3P6A A;  4D0O A;  3MPX A;  2KR9 A;  3KY9 A;  1X86 A;  1KZ7 A;  2DFK A;  1FOE A;  1F5X A;  3KZ1 A;  3KSY A;  3T06 A;  5FI1 A;  4MT7 A;  3JV3 A;  2DX1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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