3EP3B

Human adometdc d174n mutant with no putrescine bound
Total Genus 6
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
6
sequence length
63
structure length
54
Chain Sequence
HFFEGTEKLLEVWFSSGDLRTIPRSEWDILLKDVQCSIISVTKTDKQEAYVLSE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase.
pubmed doi rcsb
molecule tags Lyase
source organism Homo sapiens
molecule keywords S-adenosylmethionine decarboxylase beta chain
total genus 6
structure length 54
sequence length 63
ec nomenclature ec 4.1.1.50: Adenosylmethionine decarboxylase.
pdb deposition date 2008-09-29
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.360.50 Alpha Beta 2-Layer Sandwich Dihydrodipicolinate Reductase; domain 2 S-adenosylmethionine decarboxylase 3ep3B01
5TVOB 3EP8B 3H0WB 3DZ3B 3EP5B 3EPBB 3H0VB 1I7MB 3DZ2B 3EP4B 1I79B 3DZ5B 3DZ4B 1I72B 3DZ6B 1JENB 1MHMB 3EP7B 1I7CB 1I7BB 3EP3B 3EP6B 3EP9B 3DZ7B 3EPAB
chains in the Genus database with same CATH superfamily
4GQAA 5TVOB 3EP8B 3IWBB 3EC7A 5EINA 4PG7A 1RYEA 1LC3A 3M2TA 4MVJI 3C8MA 4MVJD 3KUXA 1ML3A 3STHA 1U8FO 5M6DA 3L6OO 4XQCA 4XQEA 5AQ1A 4MVJF 3NT4A 3NT2A 4R5MA 1VM6A 5EERA 4MVJG 3Q11A 1TB4A 4XQGA 4ZICA 3V1YA 4TVBA 1QKIA 4PG8A 2GLXA 1GD1O 3NTRA 2DBVO 2VYVD 3B20A 4MVJE 1B7GO 4R54A 2CZCA 1VKOA 1TA4A 1GL3A 2O48X 1E7MA 4MINA 1I79B 3K2BA 1VSVA 1NQAO 3WYBA 2PKQO 4O59O 1IHYA 5T73A 1YL5A 3TUTA 3E6AA 4LSMA 2AXQA 1K3TA 1MC4A 1DC6A 4IQ0A 4XR4A 3Q0EA 3FHLA 5J9GA 4PG5A 5A02A 3PWKA 2P2SA 3B1JA 1SZJG 3DMTA 1DC3A 1NVMB 1P1JA 1T4DA 1GADO 4R4JA 3Q2IA 1MHMB 1P9LA 1NQ5A 3DO5A 1I7BB 4NHEA 1HDGO 3WYCA 4LGVA 1GYPA 3CMCO 3DZ7B 2Q4EA 4EW6A 2IXBA 4XB2A 4H3VA 3E9MA 4MVJP 3IJPA 1PU2A 1CERA 3H0VB 3DZ2B 4LRTB 1DAPA 1DPGA 3LC1O 5C7IO 4O8JA 3HSKA 4DBVO 1H6DA 4P8RA 1FF9A 1DSSG 3DAPA 1ZH8A 1XYGA 1YWGO 3BTSA 3GFGA 3TW3A 3E82A 3CEAA 4R3NA 1H6AA 3EP5B 1Q2XA 1J5PA 3ZJXA 1QXSA 4MIEA 1DC4A 1H6CA 3OQBA 4YWJA 1NWCA 1EBUA 3O9ZA 1LA2A 4GMFA 3JSAA 2HJSA 3QVXA 1I33A 4XRGA 1OBFO 3WBBA 3V5NA 2G17A 1EBFA 3KSDO 3L4SO 3RCBA 3HJAA 1H9AA 1ARZA 4L8VA 4MIOA 2I3AA 4WNIA 3QW2A 3IWDB 5A03A 2DAPA 3CINA 1JENB 4MKXA 3FD8A 3GPDG 1CF2O 2NQTA 2VYNA 1P1HA 4R51A 1DBVO 3PQVA 3PZBA 3RC7A 2GZ2A 2EP5A 3PYXA 4ZHSA 1H93A 3I23A 3WGQA 1P1FA 2Q49A 3QY9A 5CEFA 4RL6A 1DRWA 4CLQA 5JYFA 5EIOA 1ZNQO 4JN6B 3DMTC 4INAA 3DZ6B 3OA2A 2R00A 1E5LA 2NVWA 3NTQA 4L9RA 2BH9A 2XF8A 3C1AA 2BHLA 3EP9B 1I32A 3ZDFA 4R3WA 3MZ0A 1JKFA 1GAEO 4MVJM 3VOSA 1VSUA 2GYYA 4BOYA 1H94A 5KVQA 3RVDA 2PH5A 4MVJH 5JYAA 5A06A 2EJWA 3BTVA 1U1IA 4O89A 4PG4A 5C7LO 3EZYA 2GZ1A 3K73O 3DBVO 1E77A 4HKTA 3IWCB 4GPD1 3U3XA 3DZ5B 3DZ4B 2X5KO 3UUWA 4QX6A 2QZ9A 2FPNA 4DPKA 1XEAA 2Q22A 1UYJA 3QVWA 1YL6A 2O4UX 4R5HA 1RM3A 3H0WB 5EESA 1H2HA 2H63A 5DDIP 4PG6A 1GCUA 3EPBB 4MVJA 3KSZO 3PFWO 5JY6A 1YDWA 1F06A 5JYEA 1NQOA 3EP7B 3VAZA 1EVJA 4DPLA 4IQ8A 1JN0A 1PR3A 1RM5A 3RC2A 1NBOA 4DIBA 2OZPA 2B4TO 3TUXA 1CRWG 2GZ3A 2VYVA 4II7A 4MKZA 2DUUA 1YS4A 2CVOA 3B1KA 4N54A 4R41A 3ZCXA 3K9QO 1GPDG 1S7CA 1DRVA 2R00C 5GZ6A 3E5RA 2D2IA 5A05A 3V2UA 2GD1O 3EP3B 3EP6B 3QV1A 1J0XO 3DB2A 1T4BA 3LC7O 5AVOA 3ABIA 5BNTA 2G82A 3CIFA 2HKIA 3LC2O 1I7MB 3KGDA 2I5PO 1DIHA 3CPSA 3LVFO 3TZ6A 3WBFA 1VKNA 2HO5A 1I7CB 3GNQA 3EVNA 3GDOA 1PS8A 4FB5A 1PQPA 3MOIA 3EPAB 4MIYA 2X0NA 4XB1A 3PYLA 3HNPA 3PWSA 3QVSA 3NTOA 1C3VA 1YL7A 1H9BA 3EP4B 1E5QA 2DC1A 1GR0A 2PKQP 1Q7GA 2VYND 3L0DA 3Q2KA 3IDSA 4Z0HO 4MJLA 3UW3A 3BTUA 1P1IA 1BRMA 3DZ3B 2B4RO 3H9EO 4WOJA 4YDRA 3NT5A 1NPTO 1OZAA 4GMGA 2EP7A 3WGOA 3QVTA 2I3GA 5KVSA 3HQ4O 1I72B 3RBVA 1RM4A 3BIOA 4KOAA 3WGZA 2POQX 1P1KA 3WB9A 1OFGA 3OA0A 1NWHA 2YYYA 3RC1A 4F3YA 2DPGA 5GZ3A 2X5JO 1MB4A 3E1KA 5JW6A 5A04A 3DOCA 1GYQA 1H6BA 1A7KA 3IP3A 3MTJA 3HXLA 1VC2A 4DPMA 1DRUA 1QMHA 3TV1A 3RC9A 4XQ9A 3OHSX 1TLTA 3DTYA 3WGYA 3KV3O 1LC0A 1NX6A 1IHXA 5C7OO 1E7YA 3F4LA 3PYMA 4HADA 4AK1A 5GZ1A 4O63O 1JKIA 4LRSB 2PKRA 3DR3A 1RYDA 3INGA 1DC5A 3EUWA 4WNCA 1PQUA 1QMIA 3E18A 2YV3A 3PZRA 1TVEA 4K9DA 2IXAA 4PLPA 3Q1LA 1RM0A
chains in the Genus database with same CATH topology
1I72A 5TVOB 3DZ6A 3EP8B 3H0WB 1JENA 1MHMA 1VR7A 1I7CA 3DZ3B 1JL0A 1I7BA 3EP5B 3EP7A 1TLUA 3EPBB 3EP3A 3EP6A 3EP9A 3H0VB 1I7MB 3DZ2B 3EPAA 3EP4B 3DZ7A 5TVOA 3EP8A 1I79B 3DZ5B 3DZ4B 1I72B 1TMIA 3DZ6B 3H0WA 2IIIA 1JENB 3DZ3A 1MHMB 3EP5A 3EP7B 1I7CB 1I7BB 1MSVA 3EPBA 3H0VA 1I7MA 3DZ2A 3EP3B 3EP6B 3EP4A 3EP9B 3DZ7B 3EPAB 1I79A 3DZ5A 3DZ4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5TVO B;  3EP8 B;  3H0W B;  3DZ3 B;  3EP5 B;  3EPB B;  3H0V B;  1I7M B;  3DZ2 B;  3EP4 B;  1I79 B;  3DZ5 B;  3DZ4 B;  1I72 B;  3DZ6 B;  1JEN B;  1MHM B;  3EP7 B;  1I7C B;  1I7B B;  3EP3 B;  3EP6 B;  3EP9 B;  3DZ7 B;  3EPA B; 
#chains in the Genus database with same CATH topology
 4GQA A;  5TVO B;  3EP8 B;  3IWB B;  3EC7 A;  5EIN A;  4PG7 A;  1RYE A;  1LC3 A;  3M2T A;  4MVJ I;  3C8M A;  4MVJ D;  3KUX A;  1ML3 A;  3STH A;  1U8F O;  5M6D A;  3L6O O;  4XQC A;  4XQE A;  5AQ1 A;  4MVJ F;  3NT4 A;  3NT2 A;  4R5M A;  1VM6 A;  5EER A;  4MVJ G;  3Q11 A;  1TB4 A;  4XQG A;  4ZIC A;  3V1Y A;  4TVB A;  1QKI A;  4PG8 A;  2GLX A;  1GD1 O;  3NTR A;  2DBV O;  2VYV D;  3B20 A;  4MVJ E;  1B7G O;  4R54 A;  2CZC A;  1VKO A;  1TA4 A;  1GL3 A;  2O48 X;  1E7M A;  4MIN A;  1I79 B;  3K2B A;  1VSV A;  1NQA O;  3WYB A;  2PKQ O;  4O59 O;  1IHY A;  5T73 A;  1YL5 A;  3TUT A;  3E6A A;  4LSM A;  2AXQ A;  1K3T A;  1MC4 A;  1DC6 A;  4IQ0 A;  4XR4 A;  3Q0E A;  3FHL A;  5J9G A;  4PG5 A;  5A02 A;  3PWK A;  2P2S A;  3B1J A;  1SZJ G;  3DMT A;  1DC3 A;  1NVM B;  1P1J A;  1T4D A;  1GAD O;  4R4J A;  3Q2I A;  1MHM B;  1P9L A;  1NQ5 A;  3DO5 A;  1I7B B;  4NHE A;  1HDG O;  3WYC A;  4LGV A;  1GYP A;  3CMC O;  3DZ7 B;  2Q4E A;  4EW6 A;  2IXB A;  4XB2 A;  4H3V A;  3E9M A;  4MVJ P;  3IJP A;  1PU2 A;  1CER A;  3H0V B;  3DZ2 B;  4LRT B;  1DAP A;  1DPG A;  3LC1 O;  5C7I O;  4O8J A;  3HSK A;  4DBV O;  1H6D A;  4P8R A;  1FF9 A;  1DSS G;  3DAP A;  1ZH8 A;  1XYG A;  1YWG O;  3BTS A;  3GFG A;  3TW3 A;  3E82 A;  3CEA A;  4R3N A;  1H6A A;  3EP5 B;  1Q2X A;  1J5P A;  3ZJX A;  1QXS A;  4MIE A;  1DC4 A;  1H6C A;  3OQB A;  4YWJ A;  1NWC A;  1EBU A;  3O9Z A;  1LA2 A;  4GMF A;  3JSA A;  2HJS A;  3QVX A;  1I33 A;  4XRG A;  1OBF O;  3WBB A;  3V5N A;  2G17 A;  1EBF A;  3KSD O;  3L4S O;  3RCB A;  3HJA A;  1H9A A;  1ARZ A;  4L8V A;  4MIO A;  2I3A A;  4WNI A;  3QW2 A;  3IWD B;  5A03 A;  2DAP A;  3CIN A;  1JEN B;  4MKX A;  3FD8 A;  3GPD G;  1CF2 O;  2NQT A;  2VYN A;  1P1H A;  4R51 A;  1DBV O;  3PQV A;  3PZB A;  3RC7 A;  2GZ2 A;  2EP5 A;  3PYX A;  4ZHS A;  1H93 A;  3I23 A;  3WGQ A;  1P1F A;  2Q49 A;  3QY9 A;  5CEF A;  4RL6 A;  1DRW A;  4CLQ A;  5JYF A;  5EIO A;  1ZNQ O;  4JN6 B;  3DMT C;  4INA A;  3DZ6 B;  3OA2 A;  2R00 A;  1E5L A;  2NVW A;  3NTQ A;  4L9R A;  2BH9 A;  2XF8 A;  3C1A A;  2BHL A;  3EP9 B;  1I32 A;  3ZDF A;  4R3W A;  3MZ0 A;  1JKF A;  1GAE O;  4MVJ M;  3VOS A;  1VSU A;  2GYY A;  4BOY A;  1H94 A;  5KVQ A;  3RVD A;  2PH5 A;  4MVJ H;  5JYA A;  5A06 A;  2EJW A;  3BTV A;  1U1I A;  4O89 A;  4PG4 A;  5C7L O;  3EZY A;  2GZ1 A;  3K73 O;  3DBV O;  1E77 A;  4HKT A;  3IWC B;  4GPD 1;  3U3X A;  3DZ5 B;  3DZ4 B;  2X5K O;  3UUW A;  4QX6 A;  2QZ9 A;  2FPN A;  4DPK A;  1XEA A;  2Q22 A;  1UYJ A;  3QVW A;  1YL6 A;  2O4U X;  4R5H A;  1RM3 A;  3H0W B;  5EES A;  1H2H A;  2H63 A;  5DDI P;  4PG6 A;  1GCU A;  3EPB B;  4MVJ A;  3KSZ O;  3PFW O;  5JY6 A;  1YDW A;  1F06 A;  5JYE A;  1NQO A;  3EP7 B;  3VAZ A;  1EVJ A;  4DPL A;  4IQ8 A;  1JN0 A;  1PR3 A;  1RM5 A;  3RC2 A;  1NBO A;  4DIB A;  2OZP A;  2B4T O;  3TUX A;  1CRW G;  2GZ3 A;  2VYV A;  4II7 A;  4MKZ A;  2DUU A;  1YS4 A;  2CVO A;  3B1K A;  4N54 A;  4R41 A;  3ZCX A;  3K9Q O;  1GPD G;  1S7C A;  1DRV A;  2R00 C;  5GZ6 A;  3E5R A;  2D2I A;  5A05 A;  3V2U A;  2GD1 O;  3EP3 B;  3EP6 B;  3QV1 A;  1J0X O;  3DB2 A;  1T4B A;  3LC7 O;  5AVO A;  3ABI A;  5BNT A;  2G82 A;  3CIF A;  2HKI A;  3LC2 O;  1I7M B;  3KGD A;  2I5P O;  1DIH A;  3CPS A;  3LVF O;  3TZ6 A;  3WBF A;  1VKN A;  2HO5 A;  1I7C B;  3GNQ A;  3EVN A;  3GDO A;  1PS8 A;  4FB5 A;  1PQP A;  3MOI A;  3EPA B;  4MIY A;  2X0N A;  4XB1 A;  3PYL A;  3HNP A;  3PWS A;  3QVS A;  3NTO A;  1C3V A;  1YL7 A;  1H9B A;  3EP4 B;  1E5Q A;  2DC1 A;  1GR0 A;  2PKQ P;  1Q7G A;  2VYN D;  3L0D A;  3Q2K A;  3IDS A;  4Z0H O;  4MJL A;  3UW3 A;  3BTU A;  1P1I A;  1BRM A;  3DZ3 B;  2B4R O;  3H9E O;  4WOJ A;  4YDR A;  3NT5 A;  1NPT O;  1OZA A;  4GMG A;  2EP7 A;  3WGO A;  3QVT A;  2I3G A;  5KVS A;  3HQ4 O;  1I72 B;  3RBV A;  1RM4 A;  3BIO A;  4KOA A;  3WGZ A;  2POQ X;  1P1K A;  3WB9 A;  1OFG A;  3OA0 A;  1NWH A;  2YYY A;  3RC1 A;  4F3Y A;  2DPG A;  5GZ3 A;  2X5J O;  1MB4 A;  3E1K A;  5JW6 A;  5A04 A;  3DOC A;  1GYQ A;  1H6B A;  1A7K A;  3IP3 A;  3MTJ A;  3HXL A;  1VC2 A;  4DPM A;  1DRU A;  1QMH A;  3TV1 A;  3RC9 A;  4XQ9 A;  3OHS X;  1TLT A;  3DTY A;  3WGY A;  3KV3 O;  1LC0 A;  1NX6 A;  1IHX A;  5C7O O;  1E7Y A;  3F4L A;  3PYM A;  4HAD A;  4AK1 A;  5GZ1 A;  4O63 O;  1JKI A;  4LRS B;  2PKR A;  3DR3 A;  1RYD A;  3ING A;  1DC5 A;  3EUW A;  4WNC A;  1PQU A;  1QMI A;  3E18 A;  2YV3 A;  3PZR A;  1TVE A;  4K9D A;  2IXA A;  4PLP A;  3Q1L A;  1RM0 A; 
#chains in the Genus database with same CATH homology
 1I72 A;  5TVO B;  3DZ6 A;  3EP8 B;  3H0W B;  1JEN A;  1MHM A;  1VR7 A;  1I7C A;  3DZ3 B;  1JL0 A;  1I7B A;  3EP5 B;  3EP7 A;  1TLU A;  3EPB B;  3EP3 A;  3EP6 A;  3EP9 A;  3H0V B;  1I7M B;  3DZ2 B;  3EPA A;  3EP4 B;  3DZ7 A;  5TVO A;  3EP8 A;  1I79 B;  3DZ5 B;  3DZ4 B;  1I72 B;  1TMI A;  3DZ6 B;  3H0W A;  2III A;  1JEN B;  3DZ3 A;  1MHM B;  3EP5 A;  3EP7 B;  1I7C B;  1I7B B;  1MSV A;  3EPB A;  3H0V A;  1I7M A;  3DZ2 A;  3EP3 B;  3EP6 B;  3EP4 A;  3EP9 B;  3DZ7 B;  3EPA B;  1I79 A;  3DZ5 A;  3DZ4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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