3EP8A

Human adometdc e178q mutant complexed with s-adenosylmethionine methyl ester and no putrescine bound
Total Genus 58
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
58
sequence length
260
structure length
240
Chain Sequence
SMFVSKRRFILKTCGTTLLLKALVPLLKLARDYSGFDSIQSFFYSRKNFMKPSHQGYPHRNFQEEIEFLNAIFPNGAAYCMGRMNSDCWYLYTLDFPDQTLQILMSELDPAVMDQFYMKDGVTAKDVTRESGIRDLIPGSVIDATMFNPCGYSMNGMKSDGTYWTIHITPEPEFSYVSFETNLSQTSYDDLIRKVVEVFKPGKFVTTLFVNQKIEGFKRLDCQSAMFNDYNFVFTSFAKK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Lyase
molecule keywords S-adenosylmethionine decarboxylase beta chain
publication title Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase.
pubmed doi rcsb
source organism Homo sapiens
total genus 58
structure length 240
sequence length 260
ec nomenclature ec 4.1.1.50: Adenosylmethionine decarboxylase.
pdb deposition date 2008-09-29
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.90.10 Alpha Beta 4-Layer Sandwich S-adenosylmethionine decarboxylase S-adenosylmethionine decarboxylase 3ep8A00
3H0VA 1MHMA 3EP7A 1I72A 3EP9A 1I7BA 1JENA 3EP3A 3EPAA 3DZ6A 3EP4A 1MSVA 1TLUA 5TVOA 3H0WA 1JL0A 3EP8A 1TMIA 1VR7A 3DZ4A 1I79A 1I7MA 3EP5A 3EP6A 3DZ5A 2IIIA 3DZ3A 1I7CA 3DZ2A 3EPBA 3DZ7A
chains in the Genus database with same CATH superfamily
3H0VA 1MHMA 3EP7A 1I72A 3EP9A 1I7BA 1JENA 3EP3A 3EPAA 3DZ6A 3EP4A 1MSVA 1TLUA 5TVOA 3H0WA 1JL0A 3EP8A 1TMIA 1VR7A 3DZ4A 1I79A 1I7MA 3EP5A 3EP6A 3DZ5A 2IIIA 3DZ3A 1I7CA 3DZ2A 3EPBA 3DZ7A
chains in the Genus database with same CATH topology
3DZ2B 1I7CB 1MHMA 3DZ3B 3DZ5B 3EPBB 3H0VA 3DZ7B 3EPAB 3H0VB 1MHMB 3EP7A 1I72A 3EP9A 1I7BA 1JENA 3EP3A 3EPAA 3DZ6A 3EP4A 1I72B 1MSVA 3EP7B 1JENB 3EP3B 3EP9B 1I7BB 3DZ6B 1TLUA 3EP4B 5TVOA 3H0WA 1JL0A 3EP8A 1TMIA 5TVOB 3H0WB 1VR7A 1I79A 3DZ4A 1I7MA 3EP8B 3EP5A 3EP6A 1I79B 3DZ5A 2IIIA 3DZ3A 1I7CA 3DZ2A 3DZ4B 3EP5B 1I7MB 3EPBA 3DZ7A 3EP6B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3H0V A;  1MHM A;  3EP7 A;  1I72 A;  3EP9 A;  1I7B A;  1JEN A;  3EP3 A;  3EPA A;  3DZ6 A;  3EP4 A;  1MSV A;  1TLU A;  5TVO A;  3H0W A;  1JL0 A;  3EP8 A;  1TMI A;  1VR7 A;  3DZ4 A;  1I79 A;  1I7M A;  3EP5 A;  3EP6 A;  3DZ5 A;  2III A;  3DZ3 A;  1I7C A;  3DZ2 A;  3EPB A;  3DZ7 A; 
#chains in the Genus database with same CATH topology
 3H0V A;  1MHM A;  3EP7 A;  1I72 A;  3EP9 A;  1I7B A;  1JEN A;  3EP3 A;  3EPA A;  3DZ6 A;  3EP4 A;  1MSV A;  1TLU A;  5TVO A;  3H0W A;  1JL0 A;  3EP8 A;  1TMI A;  1VR7 A;  3DZ4 A;  1I79 A;  1I7M A;  3EP5 A;  3EP6 A;  3DZ5 A;  2III A;  3DZ3 A;  1I7C A;  3DZ2 A;  3EPB A;  3DZ7 A; 
#chains in the Genus database with same CATH homology
 3DZ2 B;  1I7C B;  1MHM A;  3DZ3 B;  3DZ5 B;  3EPB B;  3H0V A;  3DZ7 B;  3EPA B;  3H0V B;  1MHM B;  3EP7 A;  1I72 A;  3EP9 A;  1I7B A;  1JEN A;  3EP3 A;  3EPA A;  3DZ6 A;  3EP4 A;  1I72 B;  1MSV A;  3EP7 B;  1JEN B;  3EP3 B;  3EP9 B;  1I7B B;  3DZ6 B;  1TLU A;  3EP4 B;  5TVO A;  3H0W A;  1JL0 A;  3EP8 A;  1TMI A;  5TVO B;  3H0W B;  1VR7 A;  1I79 A;  3DZ4 A;  1I7M A;  3EP8 B;  3EP5 A;  3EP6 A;  1I79 B;  3DZ5 A;  2III A;  3DZ3 A;  1I7C A;  3DZ2 A;  3DZ4 B;  3EP5 B;  1I7M B;  3EPB A;  3DZ7 A;  3EP6 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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