3EP8B

Human adometdc e178q mutant complexed with s-adenosylmethionine methyl ester and no putrescine bound
Total Genus 6
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
6
sequence length
64
structure length
57
Chain Sequence
AHFFEGTEKLLEVWFSQGSGDLRTIPRSEWDILLKDVQCSIISVTKTDKQEAYVLSE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase.
pubmed doi rcsb
molecule tags Lyase
source organism Homo sapiens
molecule keywords S-adenosylmethionine decarboxylase beta chain
total genus 6
structure length 57
sequence length 64
ec nomenclature ec 4.1.1.50: Adenosylmethionine decarboxylase.
pdb deposition date 2008-09-29
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.360.50 Alpha Beta 2-Layer Sandwich Dihydrodipicolinate Reductase; domain 2 S-adenosylmethionine decarboxylase 3ep8B01
3DZ5B 1I79B 3DZ2B 3EP9B 3EP3B 1MHMB 1I7CB 3EP7B 1I7BB 1I72B 1JENB 5TVOB 3DZ7B 3H0WB 1I7MB 3EP5B 3EP6B 3EP8B 3EPBB 3EPAB 3DZ3B 3DZ6B 3EP4B 3DZ4B 3H0VB
chains in the Genus database with same CATH superfamily
1QMIA 1H93A 3B20A 1PQPA 2FPNA 3DTYA 4DBVO 3K2BA 2AXQA 1JENB 1VKOA 3WBBA 4F3YA 5DDIP 2G17A 1I33A 2PKQP 3WGYA 2R00A 4TVBA 4R41A 2VYVD 1DBVO 4H3VA 4FB5A 1BRMA 4HADA 3QVTA 1OFGA 5EERA 1P1IA 4MVJD 2PKRA 1RYEA 3CPSA 1P1KA 4LSMA 1F06A 1DAPA 4L8VA 3PQVA 4PG6A 1GR0A 1TB4A 1ARZA 3PFWO 3K73O 3EP6B 4R3NA 1NWHA 3BTVA 1RYDA 3K9QO 2XF8A 3TW3A 3NTQA 1VM6A 1NBOA 3DBVO 3NT5A 4PG5A 2DAPA 2HKIA 3DR3A 1YL5A 4O8JA 3DZ7B 1YS4A 4JN6B 3QVXA 5A02A 3VAZA 3EPBB 4KOAA 4WOJA 3DZ6B 3LC1O 5GZ6A 2GZ1A 1NPTO 4MVJM 2IXAA 1MHMB 3B1JA 3RC2A 1MB4A 5AQ1A 2PH5A 1NX6A 3U3XA 3EP5B 3ZDFA 3CEAA 3TZ6A 1YWGO 3QVSA 4II7A 5M6DA 3QV1A 3HNPA 1OBFO 5EINA 1DC4A 1RM5A 2O48X 4PG7A 1YDWA 4R3WA 4CLQA 1DRUA 4RL6A 4GPD1 3RC1A 3LVFO 4PG8A 3GNQA 3IWCB 3PYXA 2CZCA 2HO5A 1T4BA 1GYPA 3DAPA 3UUWA 1NVMB 3DMTA 4GMGA 3HQ4O 2VYND 3H0VB 1PU2A 1P1JA 1DRWA 2B4RO 2H63A 3FD8A 3RCBA 1GL3A 5C7LO 4MKXA 2GD1O 4GQAA 2BH9A 3RC7A 4DPLA 2VYVA 3EUWA 1FF9A 3KSZO 1DC6A 2CVOA 3LC7O 4MVJA 1H6CA 3C1AA 1GD1O 2YV3A 3IDSA 2DC1A 4MIYA 4IQ8A 1H9BA 1YL6A 1I72B 2R00C 5AVOA 4IQ0A 5GZ3A 2GLXA 4O59O 3NTOA 3EZYA 3L6OO 3TUXA 3I23A 3L0DA 1CERA 2NVWA 4GMFA 3TV1A 3EP4B 3PWSA 4XQGA 3OQBA 3JSAA 4MVJG 3WGOA 1RM3A 1QKIA 3WGZA 4DPMA 2Q49A 1A7KA 5BNTA 3PYLA 1H6AA 2EP7A 5C7OO 3BTSA 1TVEA 3QW2A 4R51A 4XRGA 1NQAO 4PG4A 4AK1A 3RC9A 5EIOA 1T4DA 3DZ4B 2DUUA 2POQX 1LC3A 3MZ0A 1DC5A 2QZ9A 3EP9B 3EP3B 1TA4A 2O4UX 1E5QA 3V5NA 1H9AA 1E7YA 3H0WB 4MIOA 4LRSB 1P1HA 5J9GA 1LA2A 1MC4A 1DC3A 3IP3A 3O9ZA 5A04A 1LC0A 3GDOA 1CF2O 3B1KA 3DZ5B 4INAA 3Q1LA 4NHEA 3QVWA 3ZJXA 2I5PO 3E9MA 1Q7GA 4R5MA 1ML3A 5KVQA 2X5KO 4XB1A 1XYGA 2X5JO 3V2UA 1VC2A 4EW6A 1NWCA 1I7MB 3Q2KA 3FHLA 1H6BA 3PZBA 3KV3O 2VYNA 1TLTA 3DOCA 3WGQA 1U1IA 2DBVO 4P8RA 5JYFA 1J0XO 3HXLA 4MVJI 1DRVA 4R54A 3PYMA 1I7CB 3EVNA 2BHLA 2D2IA 2X0NA 3OA2A 3DO5A 1GADO 3Q0EA 4XQEA 1IHXA 3DMTC 3GFGA 1E77A 1P9LA 3IWDB 2GYYA 3PWKA 1EBUA 3NT4A 1C3VA 3BIOA 1YL7A 4O63O 2EP5A 3F4LA 3IJPA 4MJLA 1IHYA 1UYJA 4Z0HO 1I79B 2NQTA 3VOSA 3C8MA 1JKIA 2HJSA 4R4JA 3EP7B 4MVJE 1XEAA 2P2SA 5JY6A 4ZICA 5GZ1A 1DSSG 2GZ3A 5A05A 1VSVA 5T73A 3OA0A 1ZH8A 2YYYA 1NQ5A 3M2TA 2PKQO 1CRWG 5KVSA 1RM4A 4HKTA 3QY9A 4K9DA 4XB2A 1E7MA 2GZ2A 3WYBA 1HDGO 2OZPA 3STHA 5TVOB 2Q22A 3H9EO 1QXSA 4DPKA 1DPGA 3PZRA 1GPDG 1P1FA 1VSUA 1H94A 3CIFA 1I32A 4MKZA 3E82A 3CINA 1J5PA 4MINA 3DZ3B 1B7GO 1S7CA 3KGDA 1E5LA 3OHSX 4N54A 4R5HA 1JKFA 4XQCA 5CEFA 2EJWA 1PR3A 3E6AA 3L4SO 1H2HA 1EVJA 3TUTA 3RVDA 1PQUA 1ZNQO 2G82A 4MVJP 3KUXA 2DPGA 3MOIA 3ABIA 3CMCO 3EPAB 4MVJH 4BOYA 5A06A 2Q4EA 2I3GA 1H6DA 3NTRA 3UW3A 4YWJA 4YDRA 1SZJG 5A03A 3Q2IA 3DZ2B 4LRTB 5C7IO 5JW6A 1OZAA 1VKNA 3DB2A 1U8FO 3HSKA 1I7BB 3MTJA 1GCUA 3WBFA 4ZHSA 1JN0A 3EP8B 3RBVA 4L9RA 5JYEA 3E1KA 3E18A 1RM0A 1GAEO 1NQOA 1PS8A 4MIEA 3E5RA 3KSDO 4QX6A 4WNCA 5EESA 4PLPA 2B4TO 4MVJF 3LC2O 3IWBB 1Q2XA 3ZCXA 4LGVA 1K3TA 3GPDG 5JYAA 1QMHA 2IXBA 4XQ9A 4DIBA 2I3AA 3Q11A 3V1YA 1GYQA 3HJAA 1EBFA 3INGA 3EC7A 3NT2A 4XR4A 3BTUA 3WYCA 4O89A 3WB9A 1DIHA 4WNIA
chains in the Genus database with same CATH topology
3EP6A 3DZ5B 3EP8A 1I79B 3DZ2B 1TMIA 3EP9B 3EPBA 3EPAA 3DZ3A 1MHMB 3EP3B 1JL0A 1MSVA 1I7CB 3EP7B 3DZ6A 3EP4A 1I72B 1I7BB 1JENB 2IIIA 5TVOB 3DZ4A 3DZ7B 1TLUA 3H0WB 1I7MB 3H0VA 3EP5B 1VR7A 3DZ5A 3EP6B 1I79A 3DZ2A 3EP8B 3EP9A 1I7CA 1MHMA 3EP3A 3EPBB 3EP7A 3EPAB 3DZ3B 1I72A 1I7BA 1JENA 3DZ6B 5TVOA 1I7MA 3EP4B 3DZ7A 3EP5A 3H0WA 3DZ4B 3H0VB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3DZ5 B;  1I79 B;  3DZ2 B;  3EP9 B;  3EP3 B;  1MHM B;  1I7C B;  3EP7 B;  1I7B B;  1I72 B;  1JEN B;  5TVO B;  3DZ7 B;  3H0W B;  1I7M B;  3EP5 B;  3EP6 B;  3EP8 B;  3EPB B;  3EPA B;  3DZ3 B;  3DZ6 B;  3EP4 B;  3DZ4 B;  3H0V B; 
#chains in the Genus database with same CATH topology
 1QMI A;  1H93 A;  3B20 A;  1PQP A;  2FPN A;  3DTY A;  4DBV O;  3K2B A;  2AXQ A;  1JEN B;  1VKO A;  3WBB A;  4F3Y A;  5DDI P;  2G17 A;  1I33 A;  2PKQ P;  3WGY A;  2R00 A;  4TVB A;  4R41 A;  2VYV D;  1DBV O;  4H3V A;  4FB5 A;  1BRM A;  4HAD A;  3QVT A;  1OFG A;  5EER A;  1P1I A;  4MVJ D;  2PKR A;  1RYE A;  3CPS A;  1P1K A;  4LSM A;  1F06 A;  1DAP A;  4L8V A;  3PQV A;  4PG6 A;  1GR0 A;  1TB4 A;  1ARZ A;  3PFW O;  3K73 O;  3EP6 B;  4R3N A;  1NWH A;  3BTV A;  1RYD A;  3K9Q O;  2XF8 A;  3TW3 A;  3NTQ A;  1VM6 A;  1NBO A;  3DBV O;  3NT5 A;  4PG5 A;  2DAP A;  2HKI A;  3DR3 A;  1YL5 A;  4O8J A;  3DZ7 B;  1YS4 A;  4JN6 B;  3QVX A;  5A02 A;  3VAZ A;  3EPB B;  4KOA A;  4WOJ A;  3DZ6 B;  3LC1 O;  5GZ6 A;  2GZ1 A;  1NPT O;  4MVJ M;  2IXA A;  1MHM B;  3B1J A;  3RC2 A;  1MB4 A;  5AQ1 A;  2PH5 A;  1NX6 A;  3U3X A;  3EP5 B;  3ZDF A;  3CEA A;  3TZ6 A;  1YWG O;  3QVS A;  4II7 A;  5M6D A;  3QV1 A;  3HNP A;  1OBF O;  5EIN A;  1DC4 A;  1RM5 A;  2O48 X;  4PG7 A;  1YDW A;  4R3W A;  4CLQ A;  1DRU A;  4RL6 A;  4GPD 1;  3RC1 A;  3LVF O;  4PG8 A;  3GNQ A;  3IWC B;  3PYX A;  2CZC A;  2HO5 A;  1T4B A;  1GYP A;  3DAP A;  3UUW A;  1NVM B;  3DMT A;  4GMG A;  3HQ4 O;  2VYN D;  3H0V B;  1PU2 A;  1P1J A;  1DRW A;  2B4R O;  2H63 A;  3FD8 A;  3RCB A;  1GL3 A;  5C7L O;  4MKX A;  2GD1 O;  4GQA A;  2BH9 A;  3RC7 A;  4DPL A;  2VYV A;  3EUW A;  1FF9 A;  3KSZ O;  1DC6 A;  2CVO A;  3LC7 O;  4MVJ A;  1H6C A;  3C1A A;  1GD1 O;  2YV3 A;  3IDS A;  2DC1 A;  4MIY A;  4IQ8 A;  1H9B A;  1YL6 A;  1I72 B;  2R00 C;  5AVO A;  4IQ0 A;  5GZ3 A;  2GLX A;  4O59 O;  3NTO A;  3EZY A;  3L6O O;  3TUX A;  3I23 A;  3L0D A;  1CER A;  2NVW A;  4GMF A;  3TV1 A;  3EP4 B;  3PWS A;  4XQG A;  3OQB A;  3JSA A;  4MVJ G;  3WGO A;  1RM3 A;  1QKI A;  3WGZ A;  4DPM A;  2Q49 A;  1A7K A;  5BNT A;  3PYL A;  1H6A A;  2EP7 A;  5C7O O;  3BTS A;  1TVE A;  3QW2 A;  4R51 A;  4XRG A;  1NQA O;  4PG4 A;  4AK1 A;  3RC9 A;  5EIO A;  1T4D A;  3DZ4 B;  2DUU A;  2POQ X;  1LC3 A;  3MZ0 A;  1DC5 A;  2QZ9 A;  3EP9 B;  3EP3 B;  1TA4 A;  2O4U X;  1E5Q A;  3V5N A;  1H9A A;  1E7Y A;  3H0W B;  4MIO A;  4LRS B;  1P1H A;  5J9G A;  1LA2 A;  1MC4 A;  1DC3 A;  3IP3 A;  3O9Z A;  5A04 A;  1LC0 A;  3GDO A;  1CF2 O;  3B1K A;  3DZ5 B;  4INA A;  3Q1L A;  4NHE A;  3QVW A;  3ZJX A;  2I5P O;  3E9M A;  1Q7G A;  4R5M A;  1ML3 A;  5KVQ A;  2X5K O;  4XB1 A;  1XYG A;  2X5J O;  3V2U A;  1VC2 A;  4EW6 A;  1NWC A;  1I7M B;  3Q2K A;  3FHL A;  1H6B A;  3PZB A;  3KV3 O;  2VYN A;  1TLT A;  3DOC A;  3WGQ A;  1U1I A;  2DBV O;  4P8R A;  5JYF A;  1J0X O;  3HXL A;  4MVJ I;  1DRV A;  4R54 A;  3PYM A;  1I7C B;  3EVN A;  2BHL A;  2D2I A;  2X0N A;  3OA2 A;  3DO5 A;  1GAD O;  3Q0E A;  4XQE A;  1IHX A;  3DMT C;  3GFG A;  1E77 A;  1P9L A;  3IWD B;  2GYY A;  3PWK A;  1EBU A;  3NT4 A;  1C3V A;  3BIO A;  1YL7 A;  4O63 O;  2EP5 A;  3F4L A;  3IJP A;  4MJL A;  1IHY A;  1UYJ A;  4Z0H O;  1I79 B;  2NQT A;  3VOS A;  3C8M A;  1JKI A;  2HJS A;  4R4J A;  3EP7 B;  4MVJ E;  1XEA A;  2P2S A;  5JY6 A;  4ZIC A;  5GZ1 A;  1DSS G;  2GZ3 A;  5A05 A;  1VSV A;  5T73 A;  3OA0 A;  1ZH8 A;  2YYY A;  1NQ5 A;  3M2T A;  2PKQ O;  1CRW G;  5KVS A;  1RM4 A;  4HKT A;  3QY9 A;  4K9D A;  4XB2 A;  1E7M A;  2GZ2 A;  3WYB A;  1HDG O;  2OZP A;  3STH A;  5TVO B;  2Q22 A;  3H9E O;  1QXS A;  4DPK A;  1DPG A;  3PZR A;  1GPD G;  1P1F A;  1VSU A;  1H94 A;  3CIF A;  1I32 A;  4MKZ A;  3E82 A;  3CIN A;  1J5P A;  4MIN A;  3DZ3 B;  1B7G O;  1S7C A;  3KGD A;  1E5L A;  3OHS X;  4N54 A;  4R5H A;  1JKF A;  4XQC A;  5CEF A;  2EJW A;  1PR3 A;  3E6A A;  3L4S O;  1H2H A;  1EVJ A;  3TUT A;  3RVD A;  1PQU A;  1ZNQ O;  2G82 A;  4MVJ P;  3KUX A;  2DPG A;  3MOI A;  3ABI A;  3CMC O;  3EPA B;  4MVJ H;  4BOY A;  5A06 A;  2Q4E A;  2I3G A;  1H6D A;  3NTR A;  3UW3 A;  4YWJ A;  4YDR A;  1SZJ G;  5A03 A;  3Q2I A;  3DZ2 B;  4LRT B;  5C7I O;  5JW6 A;  1OZA A;  1VKN A;  3DB2 A;  1U8F O;  3HSK A;  1I7B B;  3MTJ A;  1GCU A;  3WBF A;  4ZHS A;  1JN0 A;  3EP8 B;  3RBV A;  4L9R A;  5JYE A;  3E1K A;  3E18 A;  1RM0 A;  1GAE O;  1NQO A;  1PS8 A;  4MIE A;  3E5R A;  3KSD O;  4QX6 A;  4WNC A;  5EES A;  4PLP A;  2B4T O;  4MVJ F;  3LC2 O;  3IWB B;  1Q2X A;  3ZCX A;  4LGV A;  1K3T A;  3GPD G;  5JYA A;  1QMH A;  2IXB A;  4XQ9 A;  4DIB A;  2I3A A;  3Q11 A;  3V1Y A;  1GYQ A;  3HJA A;  1EBF A;  3ING A;  3EC7 A;  3NT2 A;  4XR4 A;  3BTU A;  3WYC A;  4O89 A;  3WB9 A;  1DIH A;  4WNI A; 
#chains in the Genus database with same CATH homology
 3EP6 A;  3DZ5 B;  3EP8 A;  1I79 B;  3DZ2 B;  1TMI A;  3EP9 B;  3EPB A;  3EPA A;  3DZ3 A;  1MHM B;  3EP3 B;  1JL0 A;  1MSV A;  1I7C B;  3EP7 B;  3DZ6 A;  3EP4 A;  1I72 B;  1I7B B;  1JEN B;  2III A;  5TVO B;  3DZ4 A;  3DZ7 B;  1TLU A;  3H0W B;  1I7M B;  3H0V A;  3EP5 B;  1VR7 A;  3DZ5 A;  3EP6 B;  1I79 A;  3DZ2 A;  3EP8 B;  3EP9 A;  1I7C A;  1MHM A;  3EP3 A;  3EPB B;  3EP7 A;  3EPA B;  3DZ3 B;  1I72 A;  1I7B A;  1JEN A;  3DZ6 B;  5TVO A;  1I7M A;  3EP4 B;  3DZ7 A;  3EP5 A;  3H0W A;  3DZ4 B;  3H0V B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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