3EPAB

Human adometdc e178q mutant complexed with putrescine
Total Genus 8
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
8
sequence length
63
structure length
54
Chain Sequence
HFFEGTEKLLEVWFSSGDLRTIPRSEWDILLKDVQCSIISVTKTDKQEAYVLSE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase.
pubmed doi rcsb
molecule tags Lyase
source organism Homo sapiens
molecule keywords S-adenosylmethionine decarboxylase beta chain
total genus 8
structure length 54
sequence length 63
ec nomenclature ec 4.1.1.50: Adenosylmethionine decarboxylase.
pdb deposition date 2008-09-29
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.360.50 Alpha Beta 2-Layer Sandwich Dihydrodipicolinate Reductase; domain 2 S-adenosylmethionine decarboxylase 3epaB01
3EP5B 3DZ7B 3DZ2B 3EPAB 3DZ5B 3EP8B 5TVOB 3DZ4B 3EPBB 3EP4B 3DZ3B 3EP6B 1I7BB 3H0VB 3EP3B 1I7MB 1I72B 1JENB 1MHMB 1I79B 3DZ6B 1I7CB 3H0WB 3EP9B 3EP7B
chains in the Genus database with same CATH superfamily
2R00C 2HO5A 5GZ1A 4RL6A 3DTYA 5EESA 3Q2IA 4MVJD 3EPAB 4MJLA 1H6CA 5TVOB 1ARZA 5A02A 4MKXA 2PKRA 4R4JA 3HXLA 3EZYA 1E5LA 1PR3A 2VYND 5J9GA 3RC7A 4H3VA 1K3TA 1OBFO 3KSDO 3EP9B 3E18A 3NT2A 2R00A 3EP5B 4PG4A 1NQOA 1NWCA 1CRWG 1YS4A 2FPNA 3IWDB 3DZ4B 2O4UX 4GMGA 1F06A 3DMTC 3C1AA 2IXBA 3KUXA 1JKIA 5C7IO 2VYNA 2DUUA 1I7MB 1I72B 3DBVO 4PLPA 1E7YA 3GDOA 1Q7GA 3IDSA 1ZH8A 2BH9A 1I79B 5A06A 3PYLA 2EP7A 4BOYA 4R3WA 1DIHA 3DZ2B 3QVTA 3RC1A 3ZDFA 3RBVA 2X5JO 1NPTO 1PS8A 2X5KO 1CERA 3PZRA 1VM6A 4WOJA 3NTOA 3NT4A 1P1JA 3B1KA 4PG6A 3Q11A 3EP3B 1VKOA 4YWJA 2GYYA 4MVJI 5M6DA 1Q2XA 4O8JA 1VKNA 3L6OO 4XR4A 4MIYA 4GMFA 3Q2KA 2YV3A 4FB5A 3GFGA 4JN6B 4MINA 2YYYA 4EW6A 2Q22A 2Q49A 3ABIA 1GD1O 4PG8A 2DC1A 1C3VA 1OZAA 3FD8A 2NVWA 4O59O 4DPMA 2O48X 5JY6A 1H6BA 1H6AA 4MVJE 2VYVA 1J5PA 1DC5A 1H9AA 3TUXA 3GNQA 3MTJA 2POQX 4DPKA 1CF2O 3KGDA 5JYAA 4L9RA 3Q0EA 3CMCO 5C7LO 1EBUA 1DC6A 3H0VB 3V1YA 5KVSA 1QKIA 1P1FA 1U8FO 4XQGA 4MIEA 3E5RA 1RM3A 4LRSB 3WGQA 4R5MA 3V2UA 1MB4A 4LSMA 3ZJXA 4GQAA 4XQ9A 1I32A 2PKQP 5AQ1A 1DAPA 2P2SA 5A05A 3RC2A 2IXAA 1NVMB 2H63A 3MZ0A 3RCBA 2I5PO 4DBVO 3L0DA 2DBVO 1H94A 4P8RA 4KOAA 1JENB 1E77A 4LRTB 4HADA 3DOCA 3K2BA 4O89A 3PWKA 3RVDA 4AK1A 5CEFA 1QMHA 3L4SO 1A7KA 1PQUA 3TV1A 4DIBA 3DZ7B 1TA4A 3EP8B 1GAEO 1SZJG 3PFWO 2DAPA 1P1KA 2X0NA 3BTVA 1I7BB 3LC1O 3STHA 4R41A 3U3XA 4GPD1 3BTSA 1VSUA 3PYMA 2PH5A 2HJSA 3PYXA 3ZCXA 1LA2A 5DDIP 4TVBA 2G82A 4ZICA 1GR0A 3DAPA 3BTUA 2EP5A 1NWHA 5EERA 1S7CA 4MKZA 3DMTA 3HQ4O 4R3NA 4PG5A 1ML3A 2DPGA 5GZ3A 3CINA 1DRUA 2B4RO 5A03A 3Q1LA 5JYFA 1NBOA 3K73O 2VYVD 3INGA 1TVEA 1YDWA 4R51A 2B4TO 1ZNQO 1HDGO 3IWCB 3LVFO 1RYEA 3PZBA 1NX6A 4WNIA 1IHXA 1H2HA 3E6AA 3EP6B 3NTQA 1GYQA 3KV3O 5A04A 3WGYA 1I33A 4YDRA 1U1IA 3EC7A 1MHMB 4DPLA 2AXQA 3RC9A 3CEAA 1I7CB 3H0WB 3DR3A 3TW3A 1GCUA 4IQ8A 3CIFA 4CLQA 3MOIA 1TLTA 3KSZO 1E5QA 4K9DA 5JW6A 3HNPA 3OHSX 1QMIA 1H9BA 4R5HA 4MVJM 3K9QO 4NHEA 1OFGA 1FF9A 3CPSA 3VAZA 1H93A 3QV1A 3HSKA 2GLXA 2GD1O 4XQCA 3EUWA 1MC4A 1H6DA 1RM5A 4XB1A 1DSSG 5C7OO 3GPDG 1QXSA 2NQTA 3WGZA 3EVNA 3EP4B 3LC2O 1GADO 4MIOA 1XYGA 3F4LA 5EINA 1YL6A 1DBVO 2GZ3A 1T4DA 1TB4A 1PU2A 4MVJG 3NT5A 3I23A 3DZ6B 4PG7A 1XEAA 5BNTA 3E82A 2G17A 1E7MA 3WYBA 2PKQO 5GZ6A 3NTRA 4MVJH 2I3AA 1B7GO 3DO5A 1RM0A 4F3YA 3PWSA 3V5NA 3B1JA 3QVWA 1DRWA 4INAA 3LC7O 3VOSA 1YWGO 3EP7B 3UUWA 1NQ5A 3IJPA 4IQ0A 4MVJA 3IWBB 1LC0A 3E1KA 3UW3A 2XF8A 3EPBB 2Q4EA 1P9LA 3FHLA 1RM4A 4XRGA 1DPGA 3WB9A 1UYJA 3E9MA 1BRMA 3TZ6A 1JN0A 1P1IA 4WNCA 3BIOA 3PQVA 3QVXA 3DZ5B 2GZ2A 3WBFA 3JSAA 3WYCA 4ZHSA 1T4BA 1LC3A 1DRVA 3WBBA 3DZ3B 4QX6A 1VC2A 4L8VA 4XQEA 3TUTA 1PQPA 2GZ1A 3QVSA 3OQBA 4LGVA 3M2TA 3WGOA 3H9EO 1P1HA 4Z0HO 5T73A 3OA2A 4XB2A 3QY9A 1J0XO 1NQAO 3B20A 3IP3A 4N54A 2HKIA 3DB2A 3C8MA 1GYPA 1VSVA 2CVOA 4MVJP 2CZCA 1RYDA 1DC4A 2QZ9A 1YL7A 1YL5A 3OA0A 3HJAA 5EIOA 1JKFA 3O9ZA 3QW2A 5AVOA 1EVJA 2BHLA 4II7A 1GPDG 1GL3A 5JYEA 2D2IA 2OZPA 2I3GA 4HKTA 5KVQA 1IHYA 2EJWA 4MVJF 4O63O 1DC3A 4R54A 1EBFA
chains in the Genus database with same CATH topology
3EPAA 1VR7A 3DZ4A 3DZ5A 3EP5B 3EP8A 5TVOA 3DZ7B 1TMIA 3EPBA 3DZ2B 1MSVA 3EPAB 3DZ5B 3EP4A 3EP8B 5TVOB 3DZ4B 3DZ3A 3EP6A 3EPBB 1I7BA 3DZ2A 3H0VA 3EP4B 3EP3A 1I7MA 1I72A 3DZ3B 1JENA 3EP6B 1I7BB 1MHMA 1I79A 3H0VB 3H0WA 3EP3B 1TLUA 3DZ6A 1I7MB 1I7CA 1I72B 3EP9A 3EP7A 1JENB 2IIIA 1MHMB 3EP5A 1I79B 3DZ6B 1I7CB 1JL0A 3H0WB 3EP9B 3EP7B 3DZ7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3EP5 B;  3DZ7 B;  3DZ2 B;  3EPA B;  3DZ5 B;  3EP8 B;  5TVO B;  3DZ4 B;  3EPB B;  3EP4 B;  3DZ3 B;  3EP6 B;  1I7B B;  3H0V B;  3EP3 B;  1I7M B;  1I72 B;  1JEN B;  1MHM B;  1I79 B;  3DZ6 B;  1I7C B;  3H0W B;  3EP9 B;  3EP7 B; 
#chains in the Genus database with same CATH topology
 2R00 C;  2HO5 A;  5GZ1 A;  4RL6 A;  3DTY A;  5EES A;  3Q2I A;  4MVJ D;  3EPA B;  4MJL A;  1H6C A;  5TVO B;  1ARZ A;  5A02 A;  4MKX A;  2PKR A;  4R4J A;  3HXL A;  3EZY A;  1E5L A;  1PR3 A;  2VYN D;  5J9G A;  3RC7 A;  4H3V A;  1K3T A;  1OBF O;  3KSD O;  3EP9 B;  3E18 A;  3NT2 A;  2R00 A;  3EP5 B;  4PG4 A;  1NQO A;  1NWC A;  1CRW G;  1YS4 A;  2FPN A;  3IWD B;  3DZ4 B;  2O4U X;  4GMG A;  1F06 A;  3DMT C;  3C1A A;  2IXB A;  3KUX A;  1JKI A;  5C7I O;  2VYN A;  2DUU A;  1I7M B;  1I72 B;  3DBV O;  4PLP A;  1E7Y A;  3GDO A;  1Q7G A;  3IDS A;  1ZH8 A;  2BH9 A;  1I79 B;  5A06 A;  3PYL A;  2EP7 A;  4BOY A;  4R3W A;  1DIH A;  3DZ2 B;  3QVT A;  3RC1 A;  3ZDF A;  3RBV A;  2X5J O;  1NPT O;  1PS8 A;  2X5K O;  1CER A;  3PZR A;  1VM6 A;  4WOJ A;  3NTO A;  3NT4 A;  1P1J A;  3B1K A;  4PG6 A;  3Q11 A;  3EP3 B;  1VKO A;  4YWJ A;  2GYY A;  4MVJ I;  5M6D A;  1Q2X A;  4O8J A;  1VKN A;  3L6O O;  4XR4 A;  4MIY A;  4GMF A;  3Q2K A;  2YV3 A;  4FB5 A;  3GFG A;  4JN6 B;  4MIN A;  2YYY A;  4EW6 A;  2Q22 A;  2Q49 A;  3ABI A;  1GD1 O;  4PG8 A;  2DC1 A;  1C3V A;  1OZA A;  3FD8 A;  2NVW A;  4O59 O;  4DPM A;  2O48 X;  5JY6 A;  1H6B A;  1H6A A;  4MVJ E;  2VYV A;  1J5P A;  1DC5 A;  1H9A A;  3TUX A;  3GNQ A;  3MTJ A;  2POQ X;  4DPK A;  1CF2 O;  3KGD A;  5JYA A;  4L9R A;  3Q0E A;  3CMC O;  5C7L O;  1EBU A;  1DC6 A;  3H0V B;  3V1Y A;  5KVS A;  1QKI A;  1P1F A;  1U8F O;  4XQG A;  4MIE A;  3E5R A;  1RM3 A;  4LRS B;  3WGQ A;  4R5M A;  3V2U A;  1MB4 A;  4LSM A;  3ZJX A;  4GQA A;  4XQ9 A;  1I32 A;  2PKQ P;  5AQ1 A;  1DAP A;  2P2S A;  5A05 A;  3RC2 A;  2IXA A;  1NVM B;  2H63 A;  3MZ0 A;  3RCB A;  2I5P O;  4DBV O;  3L0D A;  2DBV O;  1H94 A;  4P8R A;  4KOA A;  1JEN B;  1E77 A;  4LRT B;  4HAD A;  3DOC A;  3K2B A;  4O89 A;  3PWK A;  3RVD A;  4AK1 A;  5CEF A;  1QMH A;  3L4S O;  1A7K A;  1PQU A;  3TV1 A;  4DIB A;  3DZ7 B;  1TA4 A;  3EP8 B;  1GAE O;  1SZJ G;  3PFW O;  2DAP A;  1P1K A;  2X0N A;  3BTV A;  1I7B B;  3LC1 O;  3STH A;  4R41 A;  3U3X A;  4GPD 1;  3BTS A;  1VSU A;  3PYM A;  2PH5 A;  2HJS A;  3PYX A;  3ZCX A;  1LA2 A;  5DDI P;  4TVB A;  2G82 A;  4ZIC A;  1GR0 A;  3DAP A;  3BTU A;  2EP5 A;  1NWH A;  5EER A;  1S7C A;  4MKZ A;  3DMT A;  3HQ4 O;  4R3N A;  4PG5 A;  1ML3 A;  2DPG A;  5GZ3 A;  3CIN A;  1DRU A;  2B4R O;  5A03 A;  3Q1L A;  5JYF A;  1NBO A;  3K73 O;  2VYV D;  3ING A;  1TVE A;  1YDW A;  4R51 A;  2B4T O;  1ZNQ O;  1HDG O;  3IWC B;  3LVF O;  1RYE A;  3PZB A;  1NX6 A;  4WNI A;  1IHX A;  1H2H A;  3E6A A;  3EP6 B;  3NTQ A;  1GYQ A;  3KV3 O;  5A04 A;  3WGY A;  1I33 A;  4YDR A;  1U1I A;  3EC7 A;  1MHM B;  4DPL A;  2AXQ A;  3RC9 A;  3CEA A;  1I7C B;  3H0W B;  3DR3 A;  3TW3 A;  1GCU A;  4IQ8 A;  3CIF A;  4CLQ A;  3MOI A;  1TLT A;  3KSZ O;  1E5Q A;  4K9D A;  5JW6 A;  3HNP A;  3OHS X;  1QMI A;  1H9B A;  4R5H A;  4MVJ M;  3K9Q O;  4NHE A;  1OFG A;  1FF9 A;  3CPS A;  3VAZ A;  1H93 A;  3QV1 A;  3HSK A;  2GLX A;  2GD1 O;  4XQC A;  3EUW A;  1MC4 A;  1H6D A;  1RM5 A;  4XB1 A;  1DSS G;  5C7O O;  3GPD G;  1QXS A;  2NQT A;  3WGZ A;  3EVN A;  3EP4 B;  3LC2 O;  1GAD O;  4MIO A;  1XYG A;  3F4L A;  5EIN A;  1YL6 A;  1DBV O;  2GZ3 A;  1T4D A;  1TB4 A;  1PU2 A;  4MVJ G;  3NT5 A;  3I23 A;  3DZ6 B;  4PG7 A;  1XEA A;  5BNT A;  3E82 A;  2G17 A;  1E7M A;  3WYB A;  2PKQ O;  5GZ6 A;  3NTR A;  4MVJ H;  2I3A A;  1B7G O;  3DO5 A;  1RM0 A;  4F3Y A;  3PWS A;  3V5N A;  3B1J A;  3QVW A;  1DRW A;  4INA A;  3LC7 O;  3VOS A;  1YWG O;  3EP7 B;  3UUW A;  1NQ5 A;  3IJP A;  4IQ0 A;  4MVJ A;  3IWB B;  1LC0 A;  3E1K A;  3UW3 A;  2XF8 A;  3EPB B;  2Q4E A;  1P9L A;  3FHL A;  1RM4 A;  4XRG A;  1DPG A;  3WB9 A;  1UYJ A;  3E9M A;  1BRM A;  3TZ6 A;  1JN0 A;  1P1I A;  4WNC A;  3BIO A;  3PQV A;  3QVX A;  3DZ5 B;  2GZ2 A;  3WBF A;  3JSA A;  3WYC A;  4ZHS A;  1T4B A;  1LC3 A;  1DRV A;  3WBB A;  3DZ3 B;  4QX6 A;  1VC2 A;  4L8V A;  4XQE A;  3TUT A;  1PQP A;  2GZ1 A;  3QVS A;  3OQB A;  4LGV A;  3M2T A;  3WGO A;  3H9E O;  1P1H A;  4Z0H O;  5T73 A;  3OA2 A;  4XB2 A;  3QY9 A;  1J0X O;  1NQA O;  3B20 A;  3IP3 A;  4N54 A;  2HKI A;  3DB2 A;  3C8M A;  1GYP A;  1VSV A;  2CVO A;  4MVJ P;  2CZC A;  1RYD A;  1DC4 A;  2QZ9 A;  1YL7 A;  1YL5 A;  3OA0 A;  3HJA A;  5EIO A;  1JKF A;  3O9Z A;  3QW2 A;  5AVO A;  1EVJ A;  2BHL A;  4II7 A;  1GPD G;  1GL3 A;  5JYE A;  2D2I A;  2OZP A;  2I3G A;  4HKT A;  5KVQ A;  1IHY A;  2EJW A;  4MVJ F;  4O63 O;  1DC3 A;  4R54 A;  1EBF A; 
#chains in the Genus database with same CATH homology
 3EPA A;  1VR7 A;  3DZ4 A;  3DZ5 A;  3EP5 B;  3EP8 A;  5TVO A;  3DZ7 B;  1TMI A;  3EPB A;  3DZ2 B;  1MSV A;  3EPA B;  3DZ5 B;  3EP4 A;  3EP8 B;  5TVO B;  3DZ4 B;  3DZ3 A;  3EP6 A;  3EPB B;  1I7B A;  3DZ2 A;  3H0V A;  3EP4 B;  3EP3 A;  1I7M A;  1I72 A;  3DZ3 B;  1JEN A;  3EP6 B;  1I7B B;  1MHM A;  1I79 A;  3H0V B;  3H0W A;  3EP3 B;  1TLU A;  3DZ6 A;  1I7M B;  1I7C A;  1I72 B;  3EP9 A;  3EP7 A;  1JEN B;  2III A;  1MHM B;  3EP5 A;  1I79 B;  3DZ6 B;  1I7C B;  1JL0 A;  3H0W B;  3EP9 B;  3EP7 B;  3DZ7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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