3ERIA

First structural evidence of substrate specificity in mammalian peroxidases: crystal structures of substrate complexes with lactoperoxidases from two different species
Total Genus 186
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
186
sequence length
595
structure length
594
Chain Sequence
SWEVGCGAPVPLVKCDENSPYRTITGDCNNRRSPALGAANRALARWLPAEYEDGLALPFGWTQRKTRNGFRVPLAREVSNKIVGYLDEEGVLDQNRSLLFMQWGQIVDHDLDFAPETELGSNEHSKTQCEEYCIQGDNCFPIMFPKNDPKLKTQGKCMPFFRAGFVCPTPPYQSLAREQINAVTSFLDASLVYGSEPLASRLRNLSSPLGLMAVNQEAWDHGLAYLPFNNKKPSPCEFINTTARVPCFLAGDFRASEQILLATAHTLLLREHNRLARELKKLNPHWNGEKLYQEARKILGAFIQIITFRDYLPIVLGSEMQKWIPPYQGYNNSVDPRISNVFTFAFRFGHMEVPSTVSRLDENYQPWGPEAELPLHTLFFNTWRIIKDGGIDPLVRGLLAKKSKLMNQDKMVTSELRNKLFQPTHKIHGFDLAAINLQRCRDHGMPGYNSWRGFCGLSQPKTLKGLQTVLKNKILAKKLMDLYKTPDNIDIWIGGNAEPMVERGRVGPLLACLLGRQFQQIRDGDRFWWENPGVFTEKQRDSLQKVSFSRLICDNTHITKVPLHAFQANNYPHDFVDCSTVDKLDLSPWASREN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Evidence of Substrate Specificity in Mammalian Peroxidases: STRUCTURE OF THE THIOCYANATE COMPLEX WITH LACTOPEROXIDASE AND ITS INTERACTIONS AT 2.4 A RESOLUTION
pubmed doi rcsb
molecule keywords Lactoperoxidase
molecule tags Oxidoreductase
total genus 186
structure length 594
sequence length 595
ec nomenclature ec 1.11.1.7: Peroxidase.
pdb deposition date 2008-10-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03098 An_peroxidase Animal haem peroxidase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.640.10 Mainly Alpha Orthogonal Bundle Myeloperoxidase, subunit C Haem peroxidase domain superfamily, animal type 3eriA00
4N7AA 3NYHA 1CQEA 4GM7A 3ZS0C 4KVKA 4COXA 4NJBA 3QF1A 4OTJA 5FF1A 3FNLA 1PGEA 1MHLC 1MYPC 3TGYA 2Z5ZA 4RRZA 3NTGA 5COXA 3I6NA 1IGXA 4MSFA 5JVZA 2PT3A 3N8WA 3LN0A 2QQTA 3LN1A 5KIRA 1EQHA 5IKTA 4C1MC 4KVJA 4E1GA 5FDQA 2E9EA 1D7WC 3KRKA 1FE2A 5F1AA 3Q9KA 3N8YA 1DDXA 2QPKA 1DNUC 4LJJA 3HS7A 1HT8A 4Y55A 3GC1A 3R5OA 5GH0A 6COXA 3GCKA 3HS6A 4DL1C 4RRXA 3N8WB 1DNWC 3HS5A 3KRQA 4Z0LA 1CXPC 3QL6A 4GN6A 4OTYA 1DIYA 1D2VC 3NAKA 3NT1A 2R5LA 1Q4GA 2NQXA 1U67A 3TZIA 5IKVA 5IKQA 1CVUA 2PUMA 4M10A 3N8YB 3UBAA 3R4XA 3MQEA 5JVYA 2GJMA 3S4FA 5B72A 4HHSA 1PXXA 3ERIA 3Q7DA 5F19A 3N8ZA 4QJQA 1PRHA 4PH9A 2EFBA 3GCJA 3ZS1C 3NTBA 3R5QA 3N8XA 1EBVA 3MDLA 3N8FA 4RUTA 2OYEP 3BXIA 3GCLA 3V6QA 3N8VA 1CX2A 5JW1A 3RR3A 3R55A 3KK6A 5FIWC 2QRBA 2IPSA 4RS0A 4RRYA 2AYLA 3QH0A 4IG5A 4KVLA 3RKEA 3QMOA 2OJVA 4M11A 1PTHA 4RRWA 3F9PC 3OLUA 4OEKA 5HPWA 4QYQA 4FM5A 2O86A 1EQGA 4O1ZA 4NT3A 4PNXA 3SXVA 3OLTA 3ERHA 1HT5A 3PGHA 4KSZA 2OYUP 1D5LC 2IKCA 3OGWA 5IKRA 5GLSA 3FAQA 3PY4A 3NIUA 2EHAA 4HHRA 1IGZA
chains in the Genus database with same CATH superfamily
4N7AA 3NYHA 1CQEA 4GM7A 3ZS0C 4KVKA 4COXA 4NJBA 3QF1A 4OTJA 5FF1A 3FNLA 1PGEA 1MHLC 1MYPC 3TGYA 2Z5ZA 4RRZA 3NTGA 5COXA 3I6NA 1IGXA 4MSFA 5JVZA 2PT3A 3N8WA 3LN0A 2QQTA 3LN1A 5KIRA 1EQHA 5IKTA 4C1MC 4KVJA 4E1GA 5FDQA 2E9EA 1D7WC 3KRKA 1FE2A 5F1AA 3Q9KA 3N8YA 1DDXA 2QPKA 1DNUC 4LJJA 3HS7A 1HT8A 4Y55A 3GC1A 3R5OA 5GH0A 6COXA 3GCKA 3HS6A 4DL1C 4RRXA 3N8WB 1DNWC 3HS5A 3KRQA 4Z0LA 1CXPC 3QL6A 4GN6A 4OTYA 1DIYA 1D2VC 3NAKA 3NT1A 2R5LA 1Q4GA 2NQXA 1U67A 3TZIA 5IKVA 5IKQA 1CVUA 2PUMA 4M10A 3N8YB 3UBAA 3R4XA 3MQEA 5JVYA 2GJMA 3S4FA 5B72A 4HHSA 1PXXA 3ERIA 3Q7DA 5F19A 3N8ZA 4QJQA 1PRHA 4PH9A 2EFBA 3GCJA 3ZS1C 3NTBA 3R5QA 3N8XA 1EBVA 3MDLA 3N8FA 4RUTA 2OYEP 3BXIA 3GCLA 3V6QA 3N8VA 1CX2A 5JW1A 3RR3A 3R55A 3KK6A 5FIWC 2QRBA 2IPSA 4RS0A 4RRYA 2AYLA 3QH0A 4IG5A 4KVLA 3RKEA 3QMOA 2OJVA 4M11A 1PTHA 4RRWA 3F9PC 3OLUA 4OEKA 5HPWA 4QYQA 4FM5A 2O86A 1EQGA 4O1ZA 4NT3A 4PNXA 3SXVA 3OLTA 3ERHA 1HT5A 3PGHA 4KSZA 2OYUP 1D5LC 2IKCA 3OGWA 5IKRA 5GLSA 3FAQA 3PY4A 3NIUA 2EHAA 4HHRA 1IGZA
chains in the Genus database with same CATH topology
4N7AA 3NYHA 1CQEA 4GM7A 3ZS0C 4KVKA 4COXA 4NJBA 3QF1A 4OTJA 5FF1A 3FNLA 1PGEA 1MHLC 1MYPC 3TGYA 2Z5ZA 4RRZA 3NTGA 5COXA 3I6NA 1IGXA 4MSFA 5JVZA 2PT3A 3N8WA 3LN0A 2QQTA 3LN1A 5KIRA 1EQHA 5IKTA 4C1MC 4KVJA 4E1GA 5FDQA 2E9EA 1D7WC 3KRKA 1FE2A 5F1AA 3Q9KA 3N8YA 1DDXA 2QPKA 1DNUC 4LJJA 3HS7A 1HT8A 4Y55A 3GC1A 3R5OA 5GH0A 6COXA 3GCKA 3HS6A 4DL1C 4RRXA 3N8WB 1DNWC 3HS5A 3KRQA 4Z0LA 1CXPC 3QL6A 4GN6A 4OTYA 1DIYA 1D2VC 3NAKA 3NT1A 2R5LA 1Q4GA 2NQXA 1U67A 3TZIA 5IKVA 5IKQA 1CVUA 2PUMA 4M10A 3N8YB 3UBAA 3R4XA 3MQEA 5JVYA 2GJMA 3S4FA 5B72A 4HHSA 1PXXA 3ERIA 3Q7DA 5F19A 3N8ZA 4QJQA 1PRHA 4PH9A 2EFBA 3GCJA 3ZS1C 3NTBA 3R5QA 3N8XA 1EBVA 3MDLA 3N8FA 4RUTA 2OYEP 3BXIA 3GCLA 3V6QA 3N8VA 1CX2A 5JW1A 3RR3A 3R55A 3KK6A 5FIWC 2QRBA 2IPSA 4RS0A 4RRYA 2AYLA 3QH0A 4IG5A 4KVLA 3RKEA 3QMOA 2OJVA 4M11A 1PTHA 4RRWA 3F9PC 3OLUA 4OEKA 5HPWA 4QYQA 4FM5A 2O86A 1EQGA 4O1ZA 4NT3A 4PNXA 3SXVA 3OLTA 3ERHA 1HT5A 3PGHA 4KSZA 2OYUP 1D5LC 2IKCA 3OGWA 5IKRA 5GLSA 3FAQA 3PY4A 3NIUA 2EHAA 4HHRA 1IGZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4N7A A;  3NYH A;  1CQE A;  4GM7 A;  3ZS0 C;  4KVK A;  4COX A;  4NJB A;  3QF1 A;  4OTJ A;  5FF1 A;  3FNL A;  1PGE A;  1MHL C;  1MYP C;  3TGY A;  2Z5Z A;  4RRZ A;  3NTG A;  5COX A;  3I6N A;  1IGX A;  4MSF A;  5JVZ A;  2PT3 A;  3N8W A;  3LN0 A;  2QQT A;  3LN1 A;  5KIR A;  1EQH A;  5IKT A;  4C1M C;  4KVJ A;  4E1G A;  5FDQ A;  2E9E A;  1D7W C;  3KRK A;  1FE2 A;  5F1A A;  3Q9K A;  3N8Y A;  1DDX A;  2QPK A;  1DNU C;  4LJJ A;  3HS7 A;  1HT8 A;  4Y55 A;  3GC1 A;  3R5O A;  5GH0 A;  6COX A;  3GCK A;  3HS6 A;  4DL1 C;  4RRX A;  3N8W B;  1DNW C;  3HS5 A;  3KRQ A;  4Z0L A;  1CXP C;  3QL6 A;  4GN6 A;  4OTY A;  1DIY A;  1D2V C;  3NAK A;  3NT1 A;  2R5L A;  1Q4G A;  2NQX A;  1U67 A;  3TZI A;  5IKV A;  5IKQ A;  1CVU A;  2PUM A;  4M10 A;  3N8Y B;  3UBA A;  3R4X A;  3MQE A;  5JVY A;  2GJM A;  3S4F A;  5B72 A;  4HHS A;  1PXX A;  3ERI A;  3Q7D A;  5F19 A;  3N8Z A;  4QJQ A;  1PRH A;  4PH9 A;  2EFB A;  3GCJ A;  3ZS1 C;  3NTB A;  3R5Q A;  3N8X A;  1EBV A;  3MDL A;  3N8F A;  4RUT A;  2OYE P;  3BXI A;  3GCL A;  3V6Q A;  3N8V A;  1CX2 A;  5JW1 A;  3RR3 A;  3R55 A;  3KK6 A;  5FIW C;  2QRB A;  2IPS A;  4RS0 A;  4RRY A;  2AYL A;  3QH0 A;  4IG5 A;  4KVL A;  3RKE A;  3QMO A;  2OJV A;  4M11 A;  1PTH A;  4RRW A;  3F9P C;  3OLU A;  4OEK A;  5HPW A;  4QYQ A;  4FM5 A;  2O86 A;  1EQG A;  4O1Z A;  4NT3 A;  4PNX A;  3SXV A;  3OLT A;  3ERH A;  1HT5 A;  3PGH A;  4KSZ A;  2OYU P;  1D5L C;  2IKC A;  3OGW A;  5IKR A;  5GLS A;  3FAQ A;  3PY4 A;  3NIU A;  2EHA A;  4HHR A;  1IGZ A; 
#chains in the Genus database with same CATH topology
 4N7A A;  3NYH A;  1CQE A;  4GM7 A;  3ZS0 C;  4KVK A;  4COX A;  4NJB A;  3QF1 A;  4OTJ A;  5FF1 A;  3FNL A;  1PGE A;  1MHL C;  1MYP C;  3TGY A;  2Z5Z A;  4RRZ A;  3NTG A;  5COX A;  3I6N A;  1IGX A;  4MSF A;  5JVZ A;  2PT3 A;  3N8W A;  3LN0 A;  2QQT A;  3LN1 A;  5KIR A;  1EQH A;  5IKT A;  4C1M C;  4KVJ A;  4E1G A;  5FDQ A;  2E9E A;  1D7W C;  3KRK A;  1FE2 A;  5F1A A;  3Q9K A;  3N8Y A;  1DDX A;  2QPK A;  1DNU C;  4LJJ A;  3HS7 A;  1HT8 A;  4Y55 A;  3GC1 A;  3R5O A;  5GH0 A;  6COX A;  3GCK A;  3HS6 A;  4DL1 C;  4RRX A;  3N8W B;  1DNW C;  3HS5 A;  3KRQ A;  4Z0L A;  1CXP C;  3QL6 A;  4GN6 A;  4OTY A;  1DIY A;  1D2V C;  3NAK A;  3NT1 A;  2R5L A;  1Q4G A;  2NQX A;  1U67 A;  3TZI A;  5IKV A;  5IKQ A;  1CVU A;  2PUM A;  4M10 A;  3N8Y B;  3UBA A;  3R4X A;  3MQE A;  5JVY A;  2GJM A;  3S4F A;  5B72 A;  4HHS A;  1PXX A;  3ERI A;  3Q7D A;  5F19 A;  3N8Z A;  4QJQ A;  1PRH A;  4PH9 A;  2EFB A;  3GCJ A;  3ZS1 C;  3NTB A;  3R5Q A;  3N8X A;  1EBV A;  3MDL A;  3N8F A;  4RUT A;  2OYE P;  3BXI A;  3GCL A;  3V6Q A;  3N8V A;  1CX2 A;  5JW1 A;  3RR3 A;  3R55 A;  3KK6 A;  5FIW C;  2QRB A;  2IPS A;  4RS0 A;  4RRY A;  2AYL A;  3QH0 A;  4IG5 A;  4KVL A;  3RKE A;  3QMO A;  2OJV A;  4M11 A;  1PTH A;  4RRW A;  3F9P C;  3OLU A;  4OEK A;  5HPW A;  4QYQ A;  4FM5 A;  2O86 A;  1EQG A;  4O1Z A;  4NT3 A;  4PNX A;  3SXV A;  3OLT A;  3ERH A;  1HT5 A;  3PGH A;  4KSZ A;  2OYU P;  1D5L C;  2IKC A;  3OGW A;  5IKR A;  5GLS A;  3FAQ A;  3PY4 A;  3NIU A;  2EHA A;  4HHR A;  1IGZ A; 
#chains in the Genus database with same CATH homology
 4N7A A;  3NYH A;  1CQE A;  4GM7 A;  3ZS0 C;  4KVK A;  4COX A;  4NJB A;  3QF1 A;  4OTJ A;  5FF1 A;  3FNL A;  1PGE A;  1MHL C;  1MYP C;  3TGY A;  2Z5Z A;  4RRZ A;  3NTG A;  5COX A;  3I6N A;  1IGX A;  4MSF A;  5JVZ A;  2PT3 A;  3N8W A;  3LN0 A;  2QQT A;  3LN1 A;  5KIR A;  1EQH A;  5IKT A;  4C1M C;  4KVJ A;  4E1G A;  5FDQ A;  2E9E A;  1D7W C;  3KRK A;  1FE2 A;  5F1A A;  3Q9K A;  3N8Y A;  1DDX A;  2QPK A;  1DNU C;  4LJJ A;  3HS7 A;  1HT8 A;  4Y55 A;  3GC1 A;  3R5O A;  5GH0 A;  6COX A;  3GCK A;  3HS6 A;  4DL1 C;  4RRX A;  3N8W B;  1DNW C;  3HS5 A;  3KRQ A;  4Z0L A;  1CXP C;  3QL6 A;  4GN6 A;  4OTY A;  1DIY A;  1D2V C;  3NAK A;  3NT1 A;  2R5L A;  1Q4G A;  2NQX A;  1U67 A;  3TZI A;  5IKV A;  5IKQ A;  1CVU A;  2PUM A;  4M10 A;  3N8Y B;  3UBA A;  3R4X A;  3MQE A;  5JVY A;  2GJM A;  3S4F A;  5B72 A;  4HHS A;  1PXX A;  3ERI A;  3Q7D A;  5F19 A;  3N8Z A;  4QJQ A;  1PRH A;  4PH9 A;  2EFB A;  3GCJ A;  3ZS1 C;  3NTB A;  3R5Q A;  3N8X A;  1EBV A;  3MDL A;  3N8F A;  4RUT A;  2OYE P;  3BXI A;  3GCL A;  3V6Q A;  3N8V A;  1CX2 A;  5JW1 A;  3RR3 A;  3R55 A;  3KK6 A;  5FIW C;  2QRB A;  2IPS A;  4RS0 A;  4RRY A;  2AYL A;  3QH0 A;  4IG5 A;  4KVL A;  3RKE A;  3QMO A;  2OJV A;  4M11 A;  1PTH A;  4RRW A;  3F9P C;  3OLU A;  4OEK A;  5HPW A;  4QYQ A;  4FM5 A;  2O86 A;  1EQG A;  4O1Z A;  4NT3 A;  4PNX A;  3SXV A;  3OLT A;  3ERH A;  1HT5 A;  3PGH A;  4KSZ A;  2OYU P;  1D5L C;  2IKC A;  3OGW A;  5IKR A;  5GLS A;  3FAQ A;  3PY4 A;  3NIU A;  2EHA A;  4HHR A;  1IGZ A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...