3EWJA

Crystal structure of catalytic domain of tace with carboxylate inhibitor
Total Genus 83
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
83
sequence length
258
structure length
254
Chain Sequence
PDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYGGSPHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Discovery of novel spirocyclopropyl hydroxamate and carboxylate compounds as TACE inhibitors.
pubmed doi rcsb
molecule keywords ADAM 17
molecule tags Hydrolase
source organism Homo sapiens
total genus 83
structure length 254
sequence length 258
chains with identical sequence B
ec nomenclature ec 3.4.24.86: ADAM 17 endopeptidase.
pdb deposition date 2008-10-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF13688 Reprolysin_5 Metallo-peptidase family M12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 3ewjA00
3I7GA 5BOYA 1XFVA 1BSWA 4FU4A 3HBUP 1QIAA 1D5JA 1USNA 3P1VA 3Q2GA 2RJPA 1QJIA 3N2VA 1GE7A 3ZVSA 3ZXHA 3LILA 4PKVA 3F1AA 2X3CA 3LEAA 5D1TA 4AXQA 1JANA 3F16A 2E3XA 1GXDA 1JAPA 2J83A 1C7KA 3F18A 5BOTA 4FVLA 5H8XA 1UMTA 3LK8A 4A7BA 1JAQA 1AF0A 4AUOA 5D3CA 3O64A 3NX7A 2SRTA 1I76A 2JT5A 4H82A 1BQQM 2OVXA 2O36A 4XBHA 2W13A 3MA2A 1KUHA 3DPEA 1XFYA 4H2EA 1S4BP 1MNCA 4L63A 1XFUA 5CUHA 1BIWA 3L0VA 1DMTA 3DNGA 2X3AA 1QUAA 3Q2HA 3B8ZA 1JAOA 2YIGA 3KEJA 4FXQA 2K2GA 1SATA 1ROSA 3EDIA 1OM7A 3G42A 3P24A 1ZP5A 4GWMA 4JPAA 3CKIA 2OW9A 4IUWA 5I2ZA 2W0DA 1OM8A 3AYUA 4H30A 1RM8A 2TCLA 1UMSA 2O3EA 1G9KA 1ND1A 2PJTA 1BZSA 1BQOA 4WF6A 5D2BA 3WV2A 2Y6DA 3N2UA 1SLMA 1EAKA 2N8RA 4QKZA 3DL1A 4JQGA 2DW2A 1CGEA 1CAQA 1MMQA 3LGPA 3DSLA 4HMAA 4EFSA 1CXVA 1D8FA 1ZS0A 2AIGP 1K7IA 4DPEA 2K9CA 3USNA 1SRPA 4WKEA 1IAAA 1OMJA 2POJA 1CQRA 4H49A 3K7NA 4JA1A 4GR0A 1R1HA 1JJ9A 3ELMA 1R55A 1B8YA 2JIHA 1Y0VA 2Z2DA 1IAEA 1Y8JA 4GWNA 2DW0A 1QIBA 4FXYP 3HY7A 1O0TA 2W14A 1HFCA 2FV5A 1JKYA 2OXZA 3RTSA 1PWWA 1HV5A 2D1OA 5I4OA 1BKCA 3HBVP 1CGFA 2WOAA 3L0TA 1BM6A 1SLNA 2HU6A 3LUNA 4ILWD 3F19A 3I7IA 2KRJA 3TT4A 4L6TA 1ZVXA 3G5CA 5LABA 1OS2A 2DW1A 3KRYA 1ZTQA 3B2ZA 1D8MA 1XFXA 5CXAA 1GE6A 4ZR5A 5B5OA 2CLTA 2OW0A 1ZXVA 4WKIA 2JT6A 4IN9A 4PKQA 1BUVM 1G4KA 3GBOA 1R54A 4CTHA 4XM7A 1KUIA 1PWVA 3EDGA 1KAPP 2USNA 1QJJA 1GKCA 1HTDA 3DPFA 5I43A 1CK7A 3KEKA 5I12A 2JNPA 3LKAA 3LJGA 1FBLA 1YOUA 1CGLA 4PKWA 4I35A 1SMPA 1A86A 1WNIA 2Y6CA 1C3IA 4GF1A 830CA 5L79A 2OY4A 4PKTA 4XM6A 1FLSA 1KUFA 4JP4A 2A8HA 2CKIA 3LIRA 4I03A 3HDAP 1HY7A 1BKCE 5BPAA 4PKSA 4GQLA 3RTTA 2FV9A 1G49A 5I3MA 2OVZA 4H84A 5CZMA 2DDFA 1IACA 3HY9A 3UVCA 4ON1A 1AYKA 4A3WA 1HOVA 4PKRA 3ZUKA 1A85A 2OXUA 4G9LA 3F15A 1Q3AA 2MZIA 5L7FA 3EDHA 5D1UA 1GKDA 2MLSA 2RJQA 3K7LA 1ATLA 1ASTA 3OHLA 5D7WA 3LMCA 4XCTA 2DDYA 3WV3A 1R1JA 1GO7P 3LQ0A 2WO8A 2WO9A 3LQBA 1EB6A 3B92A 3EHXA 1UEAA 2AYKA 2OY2A 2ERQA 3HYGA 1G05A 3OHOA 1HFSA 1IAGA 4WZVA 1OO9A 1PWPA 2OW2A 1YQYA 3WV1A 1C8TA 1OM6A 2D1NA 1OS9A 5JMYA 2E2DA 2W12A 5D1SA 2MZEA 1H71P 3HB2P 2OZRA 3BA0A 3HDBA 2I47A 3KECA 5I0LA 4H3XA 2XS3A 3KWVC 1XUDA 2W15A 2JSDA 2X3BA 966CA 2X7MA 4IJOA 3AIGA 1I1IP 1KUKA 2YB9A 3E8RA 1JH1A 1PWUA 2OXWA 2J0TA 2L0RA 1YP1A 3AYKA 3O2XA 5B5PA 4DV8A 1CIZA 1MMPA 1BKCI 1K7GA 4XM8A 3TSKA 2MLRA 1UTZA 3U1RA 1Y93A 3EHYA 4PKUA 1K7QA 1PWQA 1B3DA 1MMRA 1J7NA 1DTHA 4AYKA 3LJZA 1JK3A 3KMCA 3KMEA 2XS4A 1G12A 4JIJA 3LUMA 1QICA 1EUBA 1BUDA 4H76A 4Q1LA 1XUCA 1GE5A 1FM1A 1AKLA 1D7XA 4DF9A 1KBCA 1Z3JA 1YCMA 2MZHA 4L19A 1JIWP 1L6JA 1MMBA 2QPJA 3LE9A 4J4MA 1XFWA 1ZXCA 3F17A 4H1QA 4WK7A 1R1IA 1XURA 1SU3A 1IABA 1UTTA 4R3VA 1JIZA 1I73A 1IADA 2OW1A 3TS4A 2OI0A 3TVCA 1GO8P 3KHIA 4GR3A 4GUYA 3DWBA 1KUGA 1O0QA 2V4BA 456CA 3VI1A 4AIGA 2ERPA 4HX3A 4DD8A 3EDZA 3V96B 3VTGA 1RMZA 3SHIA 4GR8A 2EROA 4G0DA 3EWJA 3LJTA 1XFZA 3LIKA
chains in the Genus database with same CATH superfamily
3I7GA 5BOYA 1XFVA 1BSWA 4FU4A 3HBUP 1QIAA 1D5JA 1USNA 3DTIA 3P1VA 3Q2GA 2RJPA 1QJIA 3N2VA 1GE7A 3ZVSA 3ZXHA 3LILA 4PKVA 3F1AA 2X3CA 3LEAA 5D1TA 4AXQA 1JANA 3F16A 2E3XA 1GXDA 1JAPA 2J83A 1C7KA 3F18A 5BOTA 4FVLA 5H8XA 1UMTA 3LK8A 4A7BA 1JAQA 1AF0A 4AUOA 5D3CA 3O64A 3NX7A 2SRTA 1I76A 2JT5A 4H82A 1BQQM 2OVXA 2O36A 4XBHA 2W13A 3MA2A 1KUHA 3DPEA 1XFYA 4H2EA 1S4BP 1MNCA 4L63A 1XFUA 5CUHA 1BIWA 3L0VA 1DMTA 3DNGA 2X3AA 1QUAA 3Q2HA 3B8ZA 1JAOA 2YIGA 3KEJA 4FXQA 2K2GA 1SATA 1ROSA 3EDIA 1OM7A 3G42A 3P24A 1ZP5A 4GWMA 4JPAA 3CKIA 2OW9A 4IUWA 5I2ZA 2W0DA 1OM8A 3AYUA 4H30A 1RM8A 2TCLA 2YUFA 1UMSA 2O3EA 1G9KA 1ND1A 2PJTA 1BZSA 1BQOA 4WF6A 5D2BA 3WV2A 2Y6DA 3N2UA 1SLMA 1EAKA 2N8RA 4QKZA 3DL1A 4JQGA 2DW2A 1CGEA 1CAQA 1MMQA 3LGPA 3DSLA 4HMAA 4EFSA 1CXVA 1D8FA 1ZS0A 2AIGP 1K7IA 4DPEA 2K9CA 3USNA 1SRPA 4WKEA 1IAAA 1OMJA 2POJA 1CQRA 4H49A 3K7NA 4JA1A 4GR0A 1R1HA 1JJ9A 3ELMA 1R55A 1B8YA 2JIHA 1Y0VA 2Z2DA 1IAEA 1Y8JA 4GWNA 2DW0A 1QIBA 4FXYP 3HY7A 1O0TA 2W14A 1HFCA 2FV5A 1JKYA 2OXZA 3RTSA 1PWWA 1HV5A 2D1OA 5I4OA 1BKCA 3HBVP 1CGFA 2WOAA 3L0TA 1BM6A 1SLNA 2HU6A 3LUNA 4ILWD 3F19A 3I7IA 2KRJA 3TT4A 4L6TA 1ZVXA 3G5CA 5LABA 1OS2A 2DW1A 3KRYA 1ZTQA 3B2ZA 1D8MA 1XFXA 5CXAA 1GE6A 4ZR5A 5B5OA 2CLTA 2OW0A 1ZXVA 4WKIA 2JT6A 4IN9A 4PKQA 1BUVM 1G4KA 3GBOA 1R54A 4CTHA 4XM7A 1KUIA 1PWVA 3EDGA 1KAPP 2USNA 1QJJA 1GKCA 1HTDA 3DPFA 5I43A 1CK7A 3KEKA 5I12A 2JNPA 3LKAA 3LJGA 1FBLA 1YOUA 1CGLA 1OZ9A 4PKWA 4I35A 1SMPA 1A86A 1WNIA 2Y6CA 1C3IA 4GF1A 830CA 5L79A 2OY4A 4PKTA 4XM6A 1FLSA 1KUFA 4JP4A 2A8HA 2CKIA 3LIRA 4I03A 3HDAP 1HY7A 1BKCE 1TVIA 5BPAA 4PKSA 4GQLA 3RTTA 2FV9A 1G49A 5I3MA 2OVZA 4H84A 5CZMA 2DDFA 1IACA 3HY9A 3UVCA 4ON1A 1AYKA 4A3WA 1HOVA 4PKRA 3ZUKA 1A85A 2OXUA 4G9LA 3F15A 1Q3AA 2MZIA 1XAXA 5L7FA 3EDHA 5D1UA 1GKDA 2MLSA 2RJQA 3K7LA 1ATLA 1ASTA 3OHLA 5D7WA 3LMCA 4XCTA 2DDYA 3WV3A 1R1JA 1GO7P 3LQ0A 2WO8A 2WO9A 3LQBA 1EB6A 3B92A 3EHXA 1UEAA 2AYKA 2OY2A 3DTEA 2ERQA 3HYGA 1G05A 3OHOA 1HFSA 1IAGA 4WZVA 1OO9A 1PWPA 2OW2A 1YQYA 3WV1A 1C8TA 1OM6A 2D1NA 1OS9A 5JMYA 2E2DA 2W12A 5D1SA 2MZEA 1H71P 3HB2P 2OZRA 3BA0A 3HDBA 2I47A 3KECA 5I0LA 4H3XA 2XS3A 3KWVC 1XUDA 2W15A 2JSDA 2X3BA 966CA 2X7MA 4IJOA 3AIGA 1I1IP 1KUKA 2YB9A 3E8RA 1JH1A 1PWUA 2OXWA 2J0TA 3DTKA 2L0RA 1YP1A 3AYKA 3O2XA 5B5PA 4DV8A 1CIZA 1MMPA 1BKCI 1K7GA 4XM8A 3TSKA 2MLRA 1UTZA 3U1RA 1Y93A 3EHYA 4PKUA 1K7QA 4L7AA 1PWQA 1B3DA 1MMRA 1J7NA 1DTHA 4AYKA 3LJZA 1JK3A 3KMCA 3KMEA 2XS4A 1G12A 4JIJA 3LUMA 1QICA 1EUBA 1BUDA 4H76A 4Q1LA 1XUCA 1GE5A 1FM1A 1XM5A 1AKLA 1D7XA 4DF9A 1KBCA 1Z3JA 1YCMA 2MZHA 4L19A 1JIWP 1L6JA 1MMBA 2QPJA 3LE9A 4J4MA 1XFWA 1ZXCA 3F17A 4H1QA 4WK7A 1R1IA 1XURA 1SU3A 1IABA 1UTTA 4R3VA 1JIZA 1I73A 1IADA 2OW1A 3TS4A 2OI0A 3TVCA 1GO8P 3KHIA 4GR3A 4GUYA 3DWBA 1KUGA 1O0QA 2V4BA 456CA 3VI1A 4AIGA 2ERPA 4HX3A 4DD8A 3EDZA 3V96B 3VTGA 1RMZA 3SHIA 4GR8A 2EROA 4G0DA 3EWJA 3LJTA 1XFZA 3LIKA
chains in the Genus database with same CATH topology
3I7GA 5BOYA 1XFVA 1BSWA 4FU4A 3HBUP 1QIAA 1D5JA 1USNA 3DTIA 3P1VA 3Q2GA 2RJPA 1QJIA 3N2VA 1GE7A 3ZVSA 3ZXHA 3LILA 4PKVA 3F1AA 2X3CA 3LEAA 5D1TA 4AXQA 1JANA 3F16A 2E3XA 1GXDA 1JAPA 2J83A 1C7KA 3F18A 5BOTA 4FVLA 5H8XA 1UMTA 3LK8A 4A7BA 1JAQA 1AF0A 4AUOA 5D3CA 3O64A 3NX7A 2SRTA 1I76A 2JT5A 4H82A 1BQQM 2OVXA 2O36A 4XBHA 2W13A 3MA2A 1KUHA 3DPEA 1XFYA 4H2EA 1S4BP 1MNCA 4L63A 1XFUA 5CUHA 1BIWA 3L0VA 1DMTA 3DNGA 2X3AA 1QUAA 3Q2HA 3B8ZA 1JAOA 2YIGA 3KEJA 4FXQA 2K2GA 1SATA 1ROSA 3EDIA 1OM7A 3G42A 3P24A 1ZP5A 4GWMA 4JPAA 3CKIA 2OW9A 4IUWA 5I2ZA 2W0DA 1OM8A 3AYUA 4H30A 1RM8A 2TCLA 2YUFA 1UMSA 2O3EA 1G9KA 1ND1A 2PJTA 1BZSA 1BQOA 4WF6A 5D2BA 3WV2A 2Y6DA 3N2UA 1SLMA 1EAKA 2N8RA 4QKZA 3DL1A 4JQGA 2DW2A 1CGEA 1CAQA 1MMQA 3LGPA 3DSLA 4HMAA 4EFSA 1CXVA 1D8FA 1ZS0A 2AIGP 1K7IA 4DPEA 2K9CA 3USNA 1SRPA 4WKEA 1IAAA 1OMJA 2POJA 1CQRA 4H49A 3K7NA 4JA1A 4GR0A 1R1HA 1JJ9A 3ELMA 1R55A 1B8YA 2JIHA 1Y0VA 2Z2DA 1IAEA 1Y8JA 4GWNA 2DW0A 1QIBA 4FXYP 3HY7A 1O0TA 2W14A 1HFCA 2FV5A 1JKYA 2OXZA 3RTSA 1PWWA 1HV5A 2D1OA 5I4OA 1BKCA 3HBVP 1CGFA 2WOAA 3L0TA 1BM6A 1SLNA 2HU6A 3LUNA 4ILWD 3F19A 3I7IA 2KRJA 3TT4A 4L6TA 1ZVXA 3G5CA 5LABA 1OS2A 2DW1A 3KRYA 1ZTQA 3B2ZA 1D8MA 1XFXA 5CXAA 1GE6A 4ZR5A 5B5OA 2CLTA 2OW0A 1ZXVA 4WKIA 2JT6A 4IN9A 4PKQA 1BUVM 1G4KA 3GBOA 1R54A 4CTHA 4XM7A 1KUIA 1PWVA 3EDGA 1KAPP 2USNA 1QJJA 1GKCA 1HTDA 3DPFA 5I43A 1CK7A 3KEKA 5I12A 2JNPA 3LKAA 3LJGA 1FBLA 1YOUA 1CGLA 4PKWA 4I35A 1SMPA 1A86A 1WNIA 2Y6CA 1C3IA 4GF1A 830CA 5L79A 2OY4A 4PKTA 4XM6A 1FLSA 1KUFA 4JP4A 2A8HA 2CKIA 3LIRA 4I03A 3HDAP 1HY7A 1BKCE 5BPAA 4PKSA 4GQLA 3RTTA 2FV9A 1G49A 5I3MA 2OVZA 4H84A 5CZMA 2DDFA 1IACA 3HY9A 3UVCA 4ON1A 1AYKA 4A3WA 1HOVA 4PKRA 3ZUKA 1A85A 2OXUA 4G9LA 3F15A 1Q3AA 2MZIA 5L7FA 3EDHA 5D1UA 1GKDA 2MLSA 2RJQA 3K7LA 1ATLA 1ASTA 3OHLA 5D7WA 3LMCA 4XCTA 2DDYA 3WV3A 1R1JA 1GO7P 3LQ0A 2WO8A 2WO9A 3LQBA 1EB6A 3B92A 3EHXA 1UEAA 2AYKA 2OY2A 3DTEA 2ERQA 3HYGA 1G05A 3OHOA 1HFSA 1IAGA 4WZVA 1OO9A 1PWPA 2OW2A 1YQYA 3WV1A 1C8TA 1OM6A 2D1NA 1OS9A 5JMYA 2E2DA 2W12A 5D1SA 2MZEA 1H71P 3HB2P 2OZRA 3BA0A 3HDBA 2I47A 3KECA 5I0LA 4H3XA 2XS3A 3KWVC 1XUDA 2W15A 2JSDA 2X3BA 966CA 2X7MA 4IJOA 3AIGA 1I1IP 1KUKA 2YB9A 3E8RA 1JH1A 1PWUA 2OXWA 2J0TA 3DTKA 2L0RA 1YP1A 3AYKA 3O2XA 5B5PA 4DV8A 1CIZA 1MMPA 1BKCI 1K7GA 4XM8A 3TSKA 2MLRA 1UTZA 3U1RA 1Y93A 3EHYA 4PKUA 1K7QA 4L7AA 1PWQA 1B3DA 1MMRA 1J7NA 1DTHA 4AYKA 3LJZA 1JK3A 3KMCA 3KMEA 2XS4A 1G12A 4JIJA 3LUMA 1QICA 1EUBA 1BUDA 4H76A 4Q1LA 1XUCA 1GE5A 1FM1A 1AKLA 1D7XA 4DF9A 1KBCA 1Z3JA 1YCMA 2MZHA 4L19A 1JIWP 1L6JA 1MMBA 2QPJA 3LE9A 4J4MA 1XFWA 1ZXCA 3F17A 4H1QA 4WK7A 1R1IA 1XURA 1SU3A 1IABA 1UTTA 4R3VA 1JIZA 1I73A 1IADA 2OW1A 3TS4A 2OI0A 3TVCA 1GO8P 3KHIA 4GR3A 4GUYA 3DWBA 1KUGA 1O0QA 2V4BA 456CA 3VI1A 4AIGA 2ERPA 4HX3A 4DD8A 3EDZA 3V96B 3VTGA 1RMZA 3SHIA 4GR8A 2EROA 4G0DA 3EWJA 3LJTA 1XFZA 3LIKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3I7G A;  5BOY A;  1XFV A;  1BSW A;  4FU4 A;  3HBU P;  1QIA A;  1D5J A;  1USN A;  3P1V A;  3Q2G A;  2RJP A;  1QJI A;  3N2V A;  1GE7 A;  3ZVS A;  3ZXH A;  3LIL A;  4PKV A;  3F1A A;  2X3C A;  3LEA A;  5D1T A;  4AXQ A;  1JAN A;  3F16 A;  2E3X A;  1GXD A;  1JAP A;  2J83 A;  1C7K A;  3F18 A;  5BOT A;  4FVL A;  5H8X A;  1UMT A;  3LK8 A;  4A7B A;  1JAQ A;  1AF0 A;  4AUO A;  5D3C A;  3O64 A;  3NX7 A;  2SRT A;  1I76 A;  2JT5 A;  4H82 A;  1BQQ M;  2OVX A;  2O36 A;  4XBH A;  2W13 A;  3MA2 A;  1KUH A;  3DPE A;  1XFY A;  4H2E A;  1S4B P;  1MNC A;  4L63 A;  1XFU A;  5CUH A;  1BIW A;  3L0V A;  1DMT A;  3DNG A;  2X3A A;  1QUA A;  3Q2H A;  3B8Z A;  1JAO A;  2YIG A;  3KEJ A;  4FXQ A;  2K2G A;  1SAT A;  1ROS A;  3EDI A;  1OM7 A;  3G42 A;  3P24 A;  1ZP5 A;  4GWM A;  4JPA A;  3CKI A;  2OW9 A;  4IUW A;  5I2Z A;  2W0D A;  1OM8 A;  3AYU A;  4H30 A;  1RM8 A;  2TCL A;  1UMS A;  2O3E A;  1G9K A;  1ND1 A;  2PJT A;  1BZS A;  1BQO A;  4WF6 A;  5D2B A;  3WV2 A;  2Y6D A;  3N2U A;  1SLM A;  1EAK A;  2N8R A;  4QKZ A;  3DL1 A;  4JQG A;  2DW2 A;  1CGE A;  1CAQ A;  1MMQ A;  3LGP A;  3DSL A;  4HMA A;  4EFS A;  1CXV A;  1D8F A;  1ZS0 A;  2AIG P;  1K7I A;  4DPE A;  2K9C A;  3USN A;  1SRP A;  4WKE A;  1IAA A;  1OMJ A;  2POJ A;  1CQR A;  4H49 A;  3K7N A;  4JA1 A;  4GR0 A;  1R1H A;  1JJ9 A;  3ELM A;  1R55 A;  1B8Y A;  2JIH A;  1Y0V A;  2Z2D A;  1IAE A;  1Y8J A;  4GWN A;  2DW0 A;  1QIB A;  4FXY P;  3HY7 A;  1O0T A;  2W14 A;  1HFC A;  2FV5 A;  1JKY A;  2OXZ A;  3RTS A;  1PWW A;  1HV5 A;  2D1O A;  5I4O A;  1BKC A;  3HBV P;  1CGF A;  2WOA A;  3L0T A;  1BM6 A;  1SLN A;  2HU6 A;  3LUN A;  4ILW D;  3F19 A;  3I7I A;  2KRJ A;  3TT4 A;  4L6T A;  1ZVX A;  3G5C A;  5LAB A;  1OS2 A;  2DW1 A;  3KRY A;  1ZTQ A;  3B2Z A;  1D8M A;  1XFX A;  5CXA A;  1GE6 A;  4ZR5 A;  5B5O A;  2CLT A;  2OW0 A;  1ZXV A;  4WKI A;  2JT6 A;  4IN9 A;  4PKQ A;  1BUV M;  1G4K A;  3GBO A;  1R54 A;  4CTH A;  4XM7 A;  1KUI A;  1PWV A;  3EDG A;  1KAP P;  2USN A;  1QJJ A;  1GKC A;  1HTD A;  3DPF A;  5I43 A;  1CK7 A;  3KEK A;  5I12 A;  2JNP A;  3LKA A;  3LJG A;  1FBL A;  1YOU A;  1CGL A;  4PKW A;  4I35 A;  1SMP A;  1A86 A;  1WNI A;  2Y6C A;  1C3I A;  4GF1 A;  830C A;  5L79 A;  2OY4 A;  4PKT A;  4XM6 A;  1FLS A;  1KUF A;  4JP4 A;  2A8H A;  2CKI A;  3LIR A;  4I03 A;  3HDA P;  1HY7 A;  1BKC E;  5BPA A;  4PKS A;  4GQL A;  3RTT A;  2FV9 A;  1G49 A;  5I3M A;  2OVZ A;  4H84 A;  5CZM A;  2DDF A;  1IAC A;  3HY9 A;  3UVC A;  4ON1 A;  1AYK A;  4A3W A;  1HOV A;  4PKR A;  3ZUK A;  1A85 A;  2OXU A;  4G9L A;  3F15 A;  1Q3A A;  2MZI A;  5L7F A;  3EDH A;  5D1U A;  1GKD A;  2MLS A;  2RJQ A;  3K7L A;  1ATL A;  1AST A;  3OHL A;  5D7W A;  3LMC A;  4XCT A;  2DDY A;  3WV3 A;  1R1J A;  1GO7 P;  3LQ0 A;  2WO8 A;  2WO9 A;  3LQB A;  1EB6 A;  3B92 A;  3EHX A;  1UEA A;  2AYK A;  2OY2 A;  2ERQ A;  3HYG A;  1G05 A;  3OHO A;  1HFS A;  1IAG A;  4WZV A;  1OO9 A;  1PWP A;  2OW2 A;  1YQY A;  3WV1 A;  1C8T A;  1OM6 A;  2D1N A;  1OS9 A;  5JMY A;  2E2D A;  2W12 A;  5D1S A;  2MZE A;  1H71 P;  3HB2 P;  2OZR A;  3BA0 A;  3HDB A;  2I47 A;  3KEC A;  5I0L A;  4H3X A;  2XS3 A;  3KWV C;  1XUD A;  2W15 A;  2JSD A;  2X3B A;  966C A;  2X7M A;  4IJO A;  3AIG A;  1I1I P;  1KUK A;  2YB9 A;  3E8R A;  1JH1 A;  1PWU A;  2OXW A;  2J0T A;  2L0R A;  1YP1 A;  3AYK A;  3O2X A;  5B5P A;  4DV8 A;  1CIZ A;  1MMP A;  1BKC I;  1K7G A;  4XM8 A;  3TSK A;  2MLR A;  1UTZ A;  3U1R A;  1Y93 A;  3EHY A;  4PKU A;  1K7Q A;  1PWQ A;  1B3D A;  1MMR A;  1J7N A;  1DTH A;  4AYK A;  3LJZ A;  1JK3 A;  3KMC A;  3KME A;  2XS4 A;  1G12 A;  4JIJ A;  3LUM A;  1QIC A;  1EUB A;  1BUD A;  4H76 A;  4Q1L A;  1XUC A;  1GE5 A;  1FM1 A;  1AKL A;  1D7X A;  4DF9 A;  1KBC A;  1Z3J A;  1YCM A;  2MZH A;  4L19 A;  1JIW P;  1L6J A;  1MMB A;  2QPJ A;  3LE9 A;  4J4M A;  1XFW A;  1ZXC A;  3F17 A;  4H1Q A;  4WK7 A;  1R1I A;  1XUR A;  1SU3 A;  1IAB A;  1UTT A;  4R3V A;  1JIZ A;  1I73 A;  1IAD A;  2OW1 A;  3TS4 A;  2OI0 A;  3TVC A;  1GO8 P;  3KHI A;  4GR3 A;  4GUY A;  3DWB A;  1KUG A;  1O0Q A;  2V4B A;  456C A;  3VI1 A;  4AIG A;  2ERP A;  4HX3 A;  4DD8 A;  3EDZ A;  3V96 B;  3VTG A;  1RMZ A;  3SHI A;  4GR8 A;  2ERO A;  4G0D A;  3EWJ A;  3LJT A;  1XFZ A;  3LIK A; 
#chains in the Genus database with same CATH topology
 3I7G A;  5BOY A;  1XFV A;  1BSW A;  4FU4 A;  3HBU P;  1QIA A;  1D5J A;  1USN A;  3DTI A;  3P1V A;  3Q2G A;  2RJP A;  1QJI A;  3N2V A;  1GE7 A;  3ZVS A;  3ZXH A;  3LIL A;  4PKV A;  3F1A A;  2X3C A;  3LEA A;  5D1T A;  4AXQ A;  1JAN A;  3F16 A;  2E3X A;  1GXD A;  1JAP A;  2J83 A;  1C7K A;  3F18 A;  5BOT A;  4FVL A;  5H8X A;  1UMT A;  3LK8 A;  4A7B A;  1JAQ A;  1AF0 A;  4AUO A;  5D3C A;  3O64 A;  3NX7 A;  2SRT A;  1I76 A;  2JT5 A;  4H82 A;  1BQQ M;  2OVX A;  2O36 A;  4XBH A;  2W13 A;  3MA2 A;  1KUH A;  3DPE A;  1XFY A;  4H2E A;  1S4B P;  1MNC A;  4L63 A;  1XFU A;  5CUH A;  1BIW A;  3L0V A;  1DMT A;  3DNG A;  2X3A A;  1QUA A;  3Q2H A;  3B8Z A;  1JAO A;  2YIG A;  3KEJ A;  4FXQ A;  2K2G A;  1SAT A;  1ROS A;  3EDI A;  1OM7 A;  3G42 A;  3P24 A;  1ZP5 A;  4GWM A;  4JPA A;  3CKI A;  2OW9 A;  4IUW A;  5I2Z A;  2W0D A;  1OM8 A;  3AYU A;  4H30 A;  1RM8 A;  2TCL A;  2YUF A;  1UMS A;  2O3E A;  1G9K A;  1ND1 A;  2PJT A;  1BZS A;  1BQO A;  4WF6 A;  5D2B A;  3WV2 A;  2Y6D A;  3N2U A;  1SLM A;  1EAK A;  2N8R A;  4QKZ A;  3DL1 A;  4JQG A;  2DW2 A;  1CGE A;  1CAQ A;  1MMQ A;  3LGP A;  3DSL A;  4HMA A;  4EFS A;  1CXV A;  1D8F A;  1ZS0 A;  2AIG P;  1K7I A;  4DPE A;  2K9C A;  3USN A;  1SRP A;  4WKE A;  1IAA A;  1OMJ A;  2POJ A;  1CQR A;  4H49 A;  3K7N A;  4JA1 A;  4GR0 A;  1R1H A;  1JJ9 A;  3ELM A;  1R55 A;  1B8Y A;  2JIH A;  1Y0V A;  2Z2D A;  1IAE A;  1Y8J A;  4GWN A;  2DW0 A;  1QIB A;  4FXY P;  3HY7 A;  1O0T A;  2W14 A;  1HFC A;  2FV5 A;  1JKY A;  2OXZ A;  3RTS A;  1PWW A;  1HV5 A;  2D1O A;  5I4O A;  1BKC A;  3HBV P;  1CGF A;  2WOA A;  3L0T A;  1BM6 A;  1SLN A;  2HU6 A;  3LUN A;  4ILW D;  3F19 A;  3I7I A;  2KRJ A;  3TT4 A;  4L6T A;  1ZVX A;  3G5C A;  5LAB A;  1OS2 A;  2DW1 A;  3KRY A;  1ZTQ A;  3B2Z A;  1D8M A;  1XFX A;  5CXA A;  1GE6 A;  4ZR5 A;  5B5O A;  2CLT A;  2OW0 A;  1ZXV A;  4WKI A;  2JT6 A;  4IN9 A;  4PKQ A;  1BUV M;  1G4K A;  3GBO A;  1R54 A;  4CTH A;  4XM7 A;  1KUI A;  1PWV A;  3EDG A;  1KAP P;  2USN A;  1QJJ A;  1GKC A;  1HTD A;  3DPF A;  5I43 A;  1CK7 A;  3KEK A;  5I12 A;  2JNP A;  3LKA A;  3LJG A;  1FBL A;  1YOU A;  1CGL A;  1OZ9 A;  4PKW A;  4I35 A;  1SMP A;  1A86 A;  1WNI A;  2Y6C A;  1C3I A;  4GF1 A;  830C A;  5L79 A;  2OY4 A;  4PKT A;  4XM6 A;  1FLS A;  1KUF A;  4JP4 A;  2A8H A;  2CKI A;  3LIR A;  4I03 A;  3HDA P;  1HY7 A;  1BKC E;  1TVI A;  5BPA A;  4PKS A;  4GQL A;  3RTT A;  2FV9 A;  1G49 A;  5I3M A;  2OVZ A;  4H84 A;  5CZM A;  2DDF A;  1IAC A;  3HY9 A;  3UVC A;  4ON1 A;  1AYK A;  4A3W A;  1HOV A;  4PKR A;  3ZUK A;  1A85 A;  2OXU A;  4G9L A;  3F15 A;  1Q3A A;  2MZI A;  1XAX A;  5L7F A;  3EDH A;  5D1U A;  1GKD A;  2MLS A;  2RJQ A;  3K7L A;  1ATL A;  1AST A;  3OHL A;  5D7W A;  3LMC A;  4XCT A;  2DDY A;  3WV3 A;  1R1J A;  1GO7 P;  3LQ0 A;  2WO8 A;  2WO9 A;  3LQB A;  1EB6 A;  3B92 A;  3EHX A;  1UEA A;  2AYK A;  2OY2 A;  3DTE A;  2ERQ A;  3HYG A;  1G05 A;  3OHO A;  1HFS A;  1IAG A;  4WZV A;  1OO9 A;  1PWP A;  2OW2 A;  1YQY A;  3WV1 A;  1C8T A;  1OM6 A;  2D1N A;  1OS9 A;  5JMY A;  2E2D A;  2W12 A;  5D1S A;  2MZE A;  1H71 P;  3HB2 P;  2OZR A;  3BA0 A;  3HDB A;  2I47 A;  3KEC A;  5I0L A;  4H3X A;  2XS3 A;  3KWV C;  1XUD A;  2W15 A;  2JSD A;  2X3B A;  966C A;  2X7M A;  4IJO A;  3AIG A;  1I1I P;  1KUK A;  2YB9 A;  3E8R A;  1JH1 A;  1PWU A;  2OXW A;  2J0T A;  3DTK A;  2L0R A;  1YP1 A;  3AYK A;  3O2X A;  5B5P A;  4DV8 A;  1CIZ A;  1MMP A;  1BKC I;  1K7G A;  4XM8 A;  3TSK A;  2MLR A;  1UTZ A;  3U1R A;  1Y93 A;  3EHY A;  4PKU A;  1K7Q A;  4L7A A;  1PWQ A;  1B3D A;  1MMR A;  1J7N A;  1DTH A;  4AYK A;  3LJZ A;  1JK3 A;  3KMC A;  3KME A;  2XS4 A;  1G12 A;  4JIJ A;  3LUM A;  1QIC A;  1EUB A;  1BUD A;  4H76 A;  4Q1L A;  1XUC A;  1GE5 A;  1FM1 A;  1XM5 A;  1AKL A;  1D7X A;  4DF9 A;  1KBC A;  1Z3J A;  1YCM A;  2MZH A;  4L19 A;  1JIW P;  1L6J A;  1MMB A;  2QPJ A;  3LE9 A;  4J4M A;  1XFW A;  1ZXC A;  3F17 A;  4H1Q A;  4WK7 A;  1R1I A;  1XUR A;  1SU3 A;  1IAB A;  1UTT A;  4R3V A;  1JIZ A;  1I73 A;  1IAD A;  2OW1 A;  3TS4 A;  2OI0 A;  3TVC A;  1GO8 P;  3KHI A;  4GR3 A;  4GUY A;  3DWB A;  1KUG A;  1O0Q A;  2V4B A;  456C A;  3VI1 A;  4AIG A;  2ERP A;  4HX3 A;  4DD8 A;  3EDZ A;  3V96 B;  3VTG A;  1RMZ A;  3SHI A;  4GR8 A;  2ERO A;  4G0D A;  3EWJ A;  3LJT A;  1XFZ A;  3LIK A; 
#chains in the Genus database with same CATH homology
 3I7G A;  5BOY A;  1XFV A;  1BSW A;  4FU4 A;  3HBU P;  1QIA A;  1D5J A;  1USN A;  3DTI A;  3P1V A;  3Q2G A;  2RJP A;  1QJI A;  3N2V A;  1GE7 A;  3ZVS A;  3ZXH A;  3LIL A;  4PKV A;  3F1A A;  2X3C A;  3LEA A;  5D1T A;  4AXQ A;  1JAN A;  3F16 A;  2E3X A;  1GXD A;  1JAP A;  2J83 A;  1C7K A;  3F18 A;  5BOT A;  4FVL A;  5H8X A;  1UMT A;  3LK8 A;  4A7B A;  1JAQ A;  1AF0 A;  4AUO A;  5D3C A;  3O64 A;  3NX7 A;  2SRT A;  1I76 A;  2JT5 A;  4H82 A;  1BQQ M;  2OVX A;  2O36 A;  4XBH A;  2W13 A;  3MA2 A;  1KUH A;  3DPE A;  1XFY A;  4H2E A;  1S4B P;  1MNC A;  4L63 A;  1XFU A;  5CUH A;  1BIW A;  3L0V A;  1DMT A;  3DNG A;  2X3A A;  1QUA A;  3Q2H A;  3B8Z A;  1JAO A;  2YIG A;  3KEJ A;  4FXQ A;  2K2G A;  1SAT A;  1ROS A;  3EDI A;  1OM7 A;  3G42 A;  3P24 A;  1ZP5 A;  4GWM A;  4JPA A;  3CKI A;  2OW9 A;  4IUW A;  5I2Z A;  2W0D A;  1OM8 A;  3AYU A;  4H30 A;  1RM8 A;  2TCL A;  2YUF A;  1UMS A;  2O3E A;  1G9K A;  1ND1 A;  2PJT A;  1BZS A;  1BQO A;  4WF6 A;  5D2B A;  3WV2 A;  2Y6D A;  3N2U A;  1SLM A;  1EAK A;  2N8R A;  4QKZ A;  3DL1 A;  4JQG A;  2DW2 A;  1CGE A;  1CAQ A;  1MMQ A;  3LGP A;  3DSL A;  4HMA A;  4EFS A;  1CXV A;  1D8F A;  1ZS0 A;  2AIG P;  1K7I A;  4DPE A;  2K9C A;  3USN A;  1SRP A;  4WKE A;  1IAA A;  1OMJ A;  2POJ A;  1CQR A;  4H49 A;  3K7N A;  4JA1 A;  4GR0 A;  1R1H A;  1JJ9 A;  3ELM A;  1R55 A;  1B8Y A;  2JIH A;  1Y0V A;  2Z2D A;  1IAE A;  1Y8J A;  4GWN A;  2DW0 A;  1QIB A;  4FXY P;  3HY7 A;  1O0T A;  2W14 A;  1HFC A;  2FV5 A;  1JKY A;  2OXZ A;  3RTS A;  1PWW A;  1HV5 A;  2D1O A;  5I4O A;  1BKC A;  3HBV P;  1CGF A;  2WOA A;  3L0T A;  1BM6 A;  1SLN A;  2HU6 A;  3LUN A;  4ILW D;  3F19 A;  3I7I A;  2KRJ A;  3TT4 A;  4L6T A;  1ZVX A;  3G5C A;  5LAB A;  1OS2 A;  2DW1 A;  3KRY A;  1ZTQ A;  3B2Z A;  1D8M A;  1XFX A;  5CXA A;  1GE6 A;  4ZR5 A;  5B5O A;  2CLT A;  2OW0 A;  1ZXV A;  4WKI A;  2JT6 A;  4IN9 A;  4PKQ A;  1BUV M;  1G4K A;  3GBO A;  1R54 A;  4CTH A;  4XM7 A;  1KUI A;  1PWV A;  3EDG A;  1KAP P;  2USN A;  1QJJ A;  1GKC A;  1HTD A;  3DPF A;  5I43 A;  1CK7 A;  3KEK A;  5I12 A;  2JNP A;  3LKA A;  3LJG A;  1FBL A;  1YOU A;  1CGL A;  4PKW A;  4I35 A;  1SMP A;  1A86 A;  1WNI A;  2Y6C A;  1C3I A;  4GF1 A;  830C A;  5L79 A;  2OY4 A;  4PKT A;  4XM6 A;  1FLS A;  1KUF A;  4JP4 A;  2A8H A;  2CKI A;  3LIR A;  4I03 A;  3HDA P;  1HY7 A;  1BKC E;  5BPA A;  4PKS A;  4GQL A;  3RTT A;  2FV9 A;  1G49 A;  5I3M A;  2OVZ A;  4H84 A;  5CZM A;  2DDF A;  1IAC A;  3HY9 A;  3UVC A;  4ON1 A;  1AYK A;  4A3W A;  1HOV A;  4PKR A;  3ZUK A;  1A85 A;  2OXU A;  4G9L A;  3F15 A;  1Q3A A;  2MZI A;  5L7F A;  3EDH A;  5D1U A;  1GKD A;  2MLS A;  2RJQ A;  3K7L A;  1ATL A;  1AST A;  3OHL A;  5D7W A;  3LMC A;  4XCT A;  2DDY A;  3WV3 A;  1R1J A;  1GO7 P;  3LQ0 A;  2WO8 A;  2WO9 A;  3LQB A;  1EB6 A;  3B92 A;  3EHX A;  1UEA A;  2AYK A;  2OY2 A;  3DTE A;  2ERQ A;  3HYG A;  1G05 A;  3OHO A;  1HFS A;  1IAG A;  4WZV A;  1OO9 A;  1PWP A;  2OW2 A;  1YQY A;  3WV1 A;  1C8T A;  1OM6 A;  2D1N A;  1OS9 A;  5JMY A;  2E2D A;  2W12 A;  5D1S A;  2MZE A;  1H71 P;  3HB2 P;  2OZR A;  3BA0 A;  3HDB A;  2I47 A;  3KEC A;  5I0L A;  4H3X A;  2XS3 A;  3KWV C;  1XUD A;  2W15 A;  2JSD A;  2X3B A;  966C A;  2X7M A;  4IJO A;  3AIG A;  1I1I P;  1KUK A;  2YB9 A;  3E8R A;  1JH1 A;  1PWU A;  2OXW A;  2J0T A;  3DTK A;  2L0R A;  1YP1 A;  3AYK A;  3O2X A;  5B5P A;  4DV8 A;  1CIZ A;  1MMP A;  1BKC I;  1K7G A;  4XM8 A;  3TSK A;  2MLR A;  1UTZ A;  3U1R A;  1Y93 A;  3EHY A;  4PKU A;  1K7Q A;  4L7A A;  1PWQ A;  1B3D A;  1MMR A;  1J7N A;  1DTH A;  4AYK A;  3LJZ A;  1JK3 A;  3KMC A;  3KME A;  2XS4 A;  1G12 A;  4JIJ A;  3LUM A;  1QIC A;  1EUB A;  1BUD A;  4H76 A;  4Q1L A;  1XUC A;  1GE5 A;  1FM1 A;  1AKL A;  1D7X A;  4DF9 A;  1KBC A;  1Z3J A;  1YCM A;  2MZH A;  4L19 A;  1JIW P;  1L6J A;  1MMB A;  2QPJ A;  3LE9 A;  4J4M A;  1XFW A;  1ZXC A;  3F17 A;  4H1Q A;  4WK7 A;  1R1I A;  1XUR A;  1SU3 A;  1IAB A;  1UTT A;  4R3V A;  1JIZ A;  1I73 A;  1IAD A;  2OW1 A;  3TS4 A;  2OI0 A;  3TVC A;  1GO8 P;  3KHI A;  4GR3 A;  4GUY A;  3DWB A;  1KUG A;  1O0Q A;  2V4B A;  456C A;  3VI1 A;  4AIG A;  2ERP A;  4HX3 A;  4DD8 A;  3EDZ A;  3V96 B;  3VTG A;  1RMZ A;  3SHI A;  4GR8 A;  2ERO A;  4G0D A;  3EWJ A;  3LJT A;  1XFZ A;  3LIK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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