3EWRA

Complex of substrate adp-ribose with hcov-229e nsp3 adrp domain
Total Genus 52
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
52
sequence length
167
structure length
167
Chain Sequence
KEKLNAFLVHDNVAFYQGDVDTVVNGVDFDFIVNAANENLAHGGGLAKALDVYTKGKLQRLSKEHIGLAGKVKVGTGVMVECDSLRIFNVVGPRKGKHERDLLIKAYNTINNEQGTPLTPILSCGIFGIKLETSLEVLLDVCNTKEVKVFVYTDTEVCKVKDFVSGL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures of two coronavirus ADP-ribose-1''-monophosphatases and their complexes with ADP-Ribose: a systematic structural analysis of the viral ADRP domain.
pubmed doi rcsb
molecule tags Hydrolase
source organism Human coronavirus 229e
molecule keywords Non-structural protein 3
total genus 52
structure length 167
sequence length 167
ec nomenclature ec 3.4.19.12: Ubiquitinyl hydrolase 1.
pdb deposition date 2008-10-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01661 Macro Macro domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.220.10 Alpha Beta 3-Layer(aba) Sandwich Leucine Aminopeptidase, subunit E; domain 1 Leucine Aminopeptidase, subunit E, domain 1 3ewrA00
3H8EA 1HJZA 1ZR3A 3EJGA 4JLLA 2ACFA 4ZX8A 2XD7A 4J4ZA 1ZR5A 1LAPA 5DUSA 3H8GA 2AFCA 3V45A 3KQZA 3EW5A 1LAMA 3SIGA 3SIJA 4ZI6A 4GVWA 5FSYA 4ETJA 2FAVA 4R6TA 4JGKA 4R76A 2VRIA 3Q6ZA 4JCAA 4J5RA 4KSIA 3SIHA 5CB3A 3T8WA 1YD9A 4K0CA 4GUAA 2J9AA 5CBMA 5CB5A 2LGRA 4ZX9A 2EWBA 3JZTA 4GVVA 3VFQA 3EWPA 3KZWA 5FSXA 3IJ3A 5FSZA 5HOLA 4ZY2A 2EEEA 3GQEA 4ZY1A 1BPNA 1TY8A 3Q71A 4JVVA 4ZYQA 3EWOA 3H8FA 1LANA 3EJFA 3PEIA 4J5SA 4KYBA 3KQXA 3ETIA 3IIDA 5E3BA 3IIFA 5CMSA 3EWRA 5AILA 1BPMA 4ABLA 4X2TA 1SPVA 3SIIA 3KR5A 2FXKA 2X47A 3KR4A 3GPQA 1BLLE 5FSUA 4ETKA 4ZY0A 1VHUA 4ABKA 3GPOA 1LCPA 2DX6A 3GQOA 3EWQA 2BFRA 3JRUA 4J5QA 4K3NA 4TU0A 2L8RA 4ESSA 2BFQA 4UMLA 4IQYA 5D8NA 4D86A 4R7MA 1NJRA 2FG1A 1TXZA 3EKEA 5HIHA 3V2BA 5FSVA 3GPGA 1GYTA
chains in the Genus database with same CATH superfamily
3H8EA 1HJZA 1ZR3A 3EJGA 4JLLA 2ACFA 4ZX8A 2XD7A 4J4ZA 1ZR5A 1LAPA 5DUSA 3H8GA 2AFCA 3V45A 3KQZA 3EW5A 2JZFA 1LAMA 3SIGA 3SIJA 4ZI6A 4GVWA 5FSYA 4ETJA 2FAVA 4R6TA 4JGKA 4R76A 2VRIA 3Q6ZA 4JCAA 4J5RA 4KSIA 2WCTA 3SIHA 5CB3A 3T8WA 1YD9A 4K0CA 4GUAA 2J9AA 5CBMA 5CB5A 2LGRA 4ZX9A 2EWBA 3JZTA 4GVVA 3VFQA 3EWPA 3KZWA 5FSXA 3IJ3A 5FSZA 5HOLA 4ZY2A 2EEEA 3GQEA 4ZY1A 1BPNA 1TY8A 3Q71A 4JVVA 2KQVA 4ZYQA 3EWOA 3H8FA 1LANA 3EJFA 3PEIA 2JZEA 4J5SA 4KYBA 3KQXA 3ETIA 3IIDA 5E3BA 3IIFA 5CMSA 3EWRA 5AILA 1BPMA 4ABLA 4X2TA 1SPVA 2RNKA 3SIIA 3KR5A 2FXKA 2X47A 3KR4A 3GPQA 1BLLE 5FSUA 4ETKA 4ZY0A 1VHUA 4ABKA 3GPOA 1LCPA 2DX6A 3GQOA 3EWQA 2BFRA 3JRUA 4J5QA 4K3NA 4TU0A 2L8RA 4ESSA 2BFQA 4UMLA 4IQYA 5D8NA 2JZDA 4D86A 4R7MA 1NJRA 2W2GA 2FG1A 1TXZA 3EKEA 5HIHA 3V2BA 5FSVA 3GPGA 1GYTA
chains in the Genus database with same CATH topology
3H8EA 1HJZA 1ZR3A 3EJGA 4JLLA 2ACFA 4ZX8A 2XD7A 4J4ZA 1ZR5A 1LAPA 5DUSA 3H8GA 2AFCA 3V45A 3KQZA 3EW5A 1LAMA 3SIGA 3SIJA 4ZI6A 4GVWA 5FSYA 4ETJA 2FAVA 4R6TA 4JGKA 4R76A 2VRIA 3Q6ZA 4JCAA 4J5RA 4KSIA 3SIHA 5CB3A 3T8WA 1YD9A 4K0CA 4GUAA 2J9AA 5CBMA 5CB5A 2LGRA 4ZX9A 2EWBA 3JZTA 4GVVA 3VFQA 3EWPA 3KZWA 5FSXA 3IJ3A 5FSZA 5HOLA 4ZY2A 2EEEA 3GQEA 4ZY1A 1BPNA 1TY8A 3Q71A 4JVVA 4ZYQA 3EWOA 3H8FA 1LANA 3EJFA 3PEIA 4J5SA 4KYBA 3KQXA 3ETIA 3IIDA 5E3BA 3IIFA 5CMSA 3EWRA 5AILA 1BPMA 4ABLA 4X2TA 1SPVA 3SIIA 3KR5A 2FXKA 2X47A 3KR4A 3GPQA 1BLLE 5FSUA 4ETKA 4ZY0A 1VHUA 4ABKA 3GPOA 1LCPA 2DX6A 3GQOA 3EWQA 2BFRA 3JRUA 4J5QA 4K3NA 4TU0A 2L8RA 4ESSA 2BFQA 4UMLA 4IQYA 5D8NA 4D86A 4R7MA 1NJRA 2FG1A 1TXZA 3EKEA 5HIHA 3V2BA 5FSVA 3GPGA 1GYTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3H8E A;  1HJZ A;  1ZR3 A;  3EJG A;  4JLL A;  2ACF A;  4ZX8 A;  2XD7 A;  4J4Z A;  1ZR5 A;  1LAP A;  5DUS A;  3H8G A;  2AFC A;  3V45 A;  3KQZ A;  3EW5 A;  1LAM A;  3SIG A;  3SIJ A;  4ZI6 A;  4GVW A;  5FSY A;  4ETJ A;  2FAV A;  4R6T A;  4JGK A;  4R76 A;  2VRI A;  3Q6Z A;  4JCA A;  4J5R A;  4KSI A;  3SIH A;  5CB3 A;  3T8W A;  1YD9 A;  4K0C A;  4GUA A;  2J9A A;  5CBM A;  5CB5 A;  2LGR A;  4ZX9 A;  2EWB A;  3JZT A;  4GVV A;  3VFQ A;  3EWP A;  3KZW A;  5FSX A;  3IJ3 A;  5FSZ A;  5HOL A;  4ZY2 A;  2EEE A;  3GQE A;  4ZY1 A;  1BPN A;  1TY8 A;  3Q71 A;  4JVV A;  4ZYQ A;  3EWO A;  3H8F A;  1LAN A;  3EJF A;  3PEI A;  4J5S A;  4KYB A;  3KQX A;  3ETI A;  3IID A;  5E3B A;  3IIF A;  5CMS A;  3EWR A;  5AIL A;  1BPM A;  4ABL A;  4X2T A;  1SPV A;  3SII A;  3KR5 A;  2FXK A;  2X47 A;  3KR4 A;  3GPQ A;  1BLL E;  5FSU A;  4ETK A;  4ZY0 A;  1VHU A;  4ABK A;  3GPO A;  1LCP A;  2DX6 A;  3GQO A;  3EWQ A;  2BFR A;  3JRU A;  4J5Q A;  4K3N A;  4TU0 A;  2L8R A;  4ESS A;  2BFQ A;  4UML A;  4IQY A;  5D8N A;  4D86 A;  4R7M A;  1NJR A;  2FG1 A;  1TXZ A;  3EKE A;  5HIH A;  3V2B A;  5FSV A;  3GPG A;  1GYT A; 
#chains in the Genus database with same CATH topology
 3H8E A;  1HJZ A;  1ZR3 A;  3EJG A;  4JLL A;  2ACF A;  4ZX8 A;  2XD7 A;  4J4Z A;  1ZR5 A;  1LAP A;  5DUS A;  3H8G A;  2AFC A;  3V45 A;  3KQZ A;  3EW5 A;  2JZF A;  1LAM A;  3SIG A;  3SIJ A;  4ZI6 A;  4GVW A;  5FSY A;  4ETJ A;  2FAV A;  4R6T A;  4JGK A;  4R76 A;  2VRI A;  3Q6Z A;  4JCA A;  4J5R A;  4KSI A;  2WCT A;  3SIH A;  5CB3 A;  3T8W A;  1YD9 A;  4K0C A;  4GUA A;  2J9A A;  5CBM A;  5CB5 A;  2LGR A;  4ZX9 A;  2EWB A;  3JZT A;  4GVV A;  3VFQ A;  3EWP A;  3KZW A;  5FSX A;  3IJ3 A;  5FSZ A;  5HOL A;  4ZY2 A;  2EEE A;  3GQE A;  4ZY1 A;  1BPN A;  1TY8 A;  3Q71 A;  4JVV A;  2KQV A;  4ZYQ A;  3EWO A;  3H8F A;  1LAN A;  3EJF A;  3PEI A;  2JZE A;  4J5S A;  4KYB A;  3KQX A;  3ETI A;  3IID A;  5E3B A;  3IIF A;  5CMS A;  3EWR A;  5AIL A;  1BPM A;  4ABL A;  4X2T A;  1SPV A;  2RNK A;  3SII A;  3KR5 A;  2FXK A;  2X47 A;  3KR4 A;  3GPQ A;  1BLL E;  5FSU A;  4ETK A;  4ZY0 A;  1VHU A;  4ABK A;  3GPO A;  1LCP A;  2DX6 A;  3GQO A;  3EWQ A;  2BFR A;  3JRU A;  4J5Q A;  4K3N A;  4TU0 A;  2L8R A;  4ESS A;  2BFQ A;  4UML A;  4IQY A;  5D8N A;  2JZD A;  4D86 A;  4R7M A;  1NJR A;  2W2G A;  2FG1 A;  1TXZ A;  3EKE A;  5HIH A;  3V2B A;  5FSV A;  3GPG A;  1GYT A; 
#chains in the Genus database with same CATH homology
 3H8E A;  1HJZ A;  1ZR3 A;  3EJG A;  4JLL A;  2ACF A;  4ZX8 A;  2XD7 A;  4J4Z A;  1ZR5 A;  1LAP A;  5DUS A;  3H8G A;  2AFC A;  3V45 A;  3KQZ A;  3EW5 A;  1LAM A;  3SIG A;  3SIJ A;  4ZI6 A;  4GVW A;  5FSY A;  4ETJ A;  2FAV A;  4R6T A;  4JGK A;  4R76 A;  2VRI A;  3Q6Z A;  4JCA A;  4J5R A;  4KSI A;  3SIH A;  5CB3 A;  3T8W A;  1YD9 A;  4K0C A;  4GUA A;  2J9A A;  5CBM A;  5CB5 A;  2LGR A;  4ZX9 A;  2EWB A;  3JZT A;  4GVV A;  3VFQ A;  3EWP A;  3KZW A;  5FSX A;  3IJ3 A;  5FSZ A;  5HOL A;  4ZY2 A;  2EEE A;  3GQE A;  4ZY1 A;  1BPN A;  1TY8 A;  3Q71 A;  4JVV A;  4ZYQ A;  3EWO A;  3H8F A;  1LAN A;  3EJF A;  3PEI A;  4J5S A;  4KYB A;  3KQX A;  3ETI A;  3IID A;  5E3B A;  3IIF A;  5CMS A;  3EWR A;  5AIL A;  1BPM A;  4ABL A;  4X2T A;  1SPV A;  3SII A;  3KR5 A;  2FXK A;  2X47 A;  3KR4 A;  3GPQ A;  1BLL E;  5FSU A;  4ETK A;  4ZY0 A;  1VHU A;  4ABK A;  3GPO A;  1LCP A;  2DX6 A;  3GQO A;  3EWQ A;  2BFR A;  3JRU A;  4J5Q A;  4K3N A;  4TU0 A;  2L8R A;  4ESS A;  2BFQ A;  4UML A;  4IQY A;  5D8N A;  4D86 A;  4R7M A;  1NJR A;  2FG1 A;  1TXZ A;  3EKE A;  5HIH A;  3V2B A;  5FSV A;  3GPG A;  1GYT A; 
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similar chains in the Genus database (?% sequence similarity)
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