3EZQB

Crystal structure of the fas/fadd death domain complex
Total Genus 36
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
36
sequence length
99
structure length
99
Chain Sequence
GEEDLCAAFNVICDNVGKDWRRLARQLKVSDTKIDSIEDRYPRNLTERVRESLRIWKNTEKENATVAHLVGALRSCQMNLVADLVQEVQQARDLQNRSG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Fas-FADD death domain complex structure unravels signalling by receptor clustering
pubmed doi rcsb
molecule tags Apoptosis
source organism Homo sapiens
molecule keywords Tumor necrosis factor receptor superfamily member 6
total genus 36
structure length 99
sequence length 99
chains with identical sequence D, F, H, J, L, N, P
ec nomenclature
pdb deposition date 2008-10-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00531 Death Death domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.533.10 Mainly Alpha Orthogonal Bundle Death Domain, Fas Death Domain, Fas 3ezqB00
4N1JA 2N83A 3YGSC 3QF2A 1PN5A 4IZ5E 1NGRA 4IZAB 2N7ZA 1DDFA 3J6JA 4JUPA 1UCPA 2L9MA 4RHWA 2N00A 3CRDA 2M5VA 2DBDA 4LWDA 2KM6A 1FADA 2LS7A 4NQKA 2DBHA 4M9SA 2G7RA 4EWIA 4N1KA 4UZ0A 2BBZA 4O9FA 1CY5A 4M9ZA 4F44A 3LQRA 2VGQA 3EZQB 4QOBA 3KATA 2DBFA 2NZ7A 1WMGA 2NSNA 4A2WA 1C15A 1E3YA 1E41A 3EZQA 3J63A 1A1ZA 2LWDA 4P4HA 4P4HI 2MN4A 1A1WA 4RHWE 4JQWA 2HM2Q 4D8OA 3CL3A 2LWEA 4DWNA 4E9MA 1Z6TA 2P1HA 1CWWA 1N3KA 3MOPA 2MS7A 3YGSP 1WXPA 2YQFA 4M9XA 2YGSA 2O71A 2D96A 1YGOA 2DO9A 2N97A 3LQQA 2BBRA 4ZBWA 2DBGA 4O6XA 2N1FA 1ICHA 2MB9A 2A5YB 2GF5A 2A9IA 4N1LA 2OF5H 4IZ7B 3MOPG 2KN6A 2F1SA 2YVIA 2B1WA 2L6AA 1D2ZB 4O7QA 3T6PA 1DGNA 2MS8A 4A2QA 4I16A 1D2ZA 4FH0A 4F42A 1WH4A 2NAQA 3MOPK 2OF5A 2N80A 4O9LA 2MPCA 2IB1A 2YU0A
chains in the Genus database with same CATH superfamily
4N1JA 2N83A 3YGSC 3QF2A 1PN5A 4IZ5E 1NGRA 4IZAB 2N7ZA 1DDFA 3J6JA 4JUPA 1UCPA 2L9MA 4RHWA 2N00A 3CRDA 2M5VA 2DBDA 4LWDA 2KM6A 1FADA 2LS7A 4NQKA 2DBHA 4M9SA 2G7RA 4EWIA 4N1KA 4UZ0A 2BBZA 4O9FA 1CY5A 4M9ZA 4F44A 3LQRA 2VGQA 3EZQB 4QOBA 3KATA 2DBFA 2NZ7A 1WMGA 2NSNA 4A2WA 1C15A 1E3YA 1E41A 3EZQA 3J63A 1A1ZA 2LWDA 4P4HA 4P4HI 2MN4A 1A1WA 4RHWE 4JQWA 2HM2Q 4D8OA 3CL3A 2LWEA 4DWNA 4E9MA 1Z6TA 2P1HA 1CWWA 1N3KA 3MOPA 2MS7A 3YGSP 1WXPA 2YQFA 4M9XA 2YGSA 2O71A 2D96A 1YGOA 2DO9A 2N97A 3LQQA 2BBRA 4ZBWA 2DBGA 4O6XA 2N1FA 1ICHA 2MB9A 2A5YB 2GF5A 2A9IA 4N1LA 2OF5H 4IZ7B 3MOPG 2KN6A 2F1SA 2YVIA 2B1WA 2L6AA 2XV9A 1D2ZB 4O7QA 3T6PA 1DGNA 2MS8A 4A2QA 4I16A 1D2ZA 4FH0A 4F42A 1WH4A 2NAQA 3MOPK 2MJMA 2N80A 2OF5A 4O9LA 2MPCA 2IB1A 2YU0A
chains in the Genus database with same CATH topology
4N1JA 2N83A 3YGSC 3QF2A 1PN5A 4IZ5E 1NGRA 4IZAB 2N7ZA 1DDFA 3J6JA 4JUPA 1UCPA 2L9MA 4RHWA 2N00A 3CRDA 2M5VA 2DBDA 4LWDA 2KM6A 1FADA 2LS7A 4NQKA 2DBHA 4M9SA 2G7RA 4EWIA 4N1KA 4UZ0A 2BBZA 4O9FA 1CY5A 4M9ZA 4F44A 3LQRA 2VGQA 3EZQB 4QOBA 3KATA 2DBFA 2NZ7A 1WMGA 2NSNA 4A2WA 1C15A 1E3YA 1E41A 3EZQA 3J63A 1A1ZA 2LWDA 4P4HA 4P4HI 2MN4A 1A1WA 4RHWE 4JQWA 2HM2Q 4D8OA 3CL3A 2LWEA 4DWNA 4E9MA 1Z6TA 2P1HA 1CWWA 1N3KA 3MOPA 2MS7A 3YGSP 1WXPA 2YQFA 4M9XA 2YGSA 2O71A 2D96A 1YGOA 2DO9A 2N97A 3LQQA 2BBRA 4ZBWA 2DBGA 4O6XA 2N1FA 1ICHA 2MB9A 2A5YB 2GF5A 2A9IA 4N1LA 2OF5H 4IZ7B 3MOPG 2KN6A 2F1SA 2YVIA 2B1WA 2L6AA 2XV9A 1D2ZB 4O7QA 3T6PA 1DGNA 2MS8A 4A2QA 4I16A 1D2ZA 4FH0A 4F42A 1WH4A 2NAQA 3MOPK 2MJMA 2N80A 2OF5A 4O9LA 2MPCA 2IB1A 2YU0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4N1J A;  2N83 A;  3YGS C;  3QF2 A;  1PN5 A;  4IZ5 E;  1NGR A;  4IZA B;  2N7Z A;  1DDF A;  3J6J A;  4JUP A;  1UCP A;  2L9M A;  4RHW A;  2N00 A;  3CRD A;  2M5V A;  2DBD A;  4LWD A;  2KM6 A;  1FAD A;  2LS7 A;  4NQK A;  2DBH A;  4M9S A;  2G7R A;  4EWI A;  4N1K A;  4UZ0 A;  2BBZ A;  4O9F A;  1CY5 A;  4M9Z A;  4F44 A;  3LQR A;  2VGQ A;  3EZQ B;  4QOB A;  3KAT A;  2DBF A;  2NZ7 A;  1WMG A;  2NSN A;  4A2W A;  1C15 A;  1E3Y A;  1E41 A;  3EZQ A;  3J63 A;  1A1Z A;  2LWD A;  4P4H A;  4P4H I;  2MN4 A;  1A1W A;  4RHW E;  4JQW A;  2HM2 Q;  4D8O A;  3CL3 A;  2LWE A;  4DWN A;  4E9M A;  1Z6T A;  2P1H A;  1CWW A;  1N3K A;  3MOP A;  2MS7 A;  3YGS P;  1WXP A;  2YQF A;  4M9X A;  2YGS A;  2O71 A;  2D96 A;  1YGO A;  2DO9 A;  2N97 A;  3LQQ A;  2BBR A;  4ZBW A;  2DBG A;  4O6X A;  2N1F A;  1ICH A;  2MB9 A;  2A5Y B;  2GF5 A;  2A9I A;  4N1L A;  2OF5 H;  4IZ7 B;  3MOP G;  2KN6 A;  2F1S A;  2YVI A;  2B1W A;  2L6A A;  1D2Z B;  4O7Q A;  3T6P A;  1DGN A;  2MS8 A;  4A2Q A;  4I16 A;  1D2Z A;  4FH0 A;  4F42 A;  1WH4 A;  2NAQ A;  3MOP K;  2OF5 A;  2N80 A;  4O9L A;  2MPC A;  2IB1 A;  2YU0 A; 
#chains in the Genus database with same CATH topology
 4N1J A;  2N83 A;  3YGS C;  3QF2 A;  1PN5 A;  4IZ5 E;  1NGR A;  4IZA B;  2N7Z A;  1DDF A;  3J6J A;  4JUP A;  1UCP A;  2L9M A;  4RHW A;  2N00 A;  3CRD A;  2M5V A;  2DBD A;  4LWD A;  2KM6 A;  1FAD A;  2LS7 A;  4NQK A;  2DBH A;  4M9S A;  2G7R A;  4EWI A;  4N1K A;  4UZ0 A;  2BBZ A;  4O9F A;  1CY5 A;  4M9Z A;  4F44 A;  3LQR A;  2VGQ A;  3EZQ B;  4QOB A;  3KAT A;  2DBF A;  2NZ7 A;  1WMG A;  2NSN A;  4A2W A;  1C15 A;  1E3Y A;  1E41 A;  3EZQ A;  3J63 A;  1A1Z A;  2LWD A;  4P4H A;  4P4H I;  2MN4 A;  1A1W A;  4RHW E;  4JQW A;  2HM2 Q;  4D8O A;  3CL3 A;  2LWE A;  4DWN A;  4E9M A;  1Z6T A;  2P1H A;  1CWW A;  1N3K A;  3MOP A;  2MS7 A;  3YGS P;  1WXP A;  2YQF A;  4M9X A;  2YGS A;  2O71 A;  2D96 A;  1YGO A;  2DO9 A;  2N97 A;  3LQQ A;  2BBR A;  4ZBW A;  2DBG A;  4O6X A;  2N1F A;  1ICH A;  2MB9 A;  2A5Y B;  2GF5 A;  2A9I A;  4N1L A;  2OF5 H;  4IZ7 B;  3MOP G;  2KN6 A;  2F1S A;  2YVI A;  2B1W A;  2L6A A;  2XV9 A;  1D2Z B;  4O7Q A;  3T6P A;  1DGN A;  2MS8 A;  4A2Q A;  4I16 A;  1D2Z A;  4FH0 A;  4F42 A;  1WH4 A;  2NAQ A;  3MOP K;  2MJM A;  2N80 A;  2OF5 A;  4O9L A;  2MPC A;  2IB1 A;  2YU0 A; 
#chains in the Genus database with same CATH homology
 4N1J A;  2N83 A;  3YGS C;  3QF2 A;  1PN5 A;  4IZ5 E;  1NGR A;  4IZA B;  2N7Z A;  1DDF A;  3J6J A;  4JUP A;  1UCP A;  2L9M A;  4RHW A;  2N00 A;  3CRD A;  2M5V A;  2DBD A;  4LWD A;  2KM6 A;  1FAD A;  2LS7 A;  4NQK A;  2DBH A;  4M9S A;  2G7R A;  4EWI A;  4N1K A;  4UZ0 A;  2BBZ A;  4O9F A;  1CY5 A;  4M9Z A;  4F44 A;  3LQR A;  2VGQ A;  3EZQ B;  4QOB A;  3KAT A;  2DBF A;  2NZ7 A;  1WMG A;  2NSN A;  4A2W A;  1C15 A;  1E3Y A;  1E41 A;  3EZQ A;  3J63 A;  1A1Z A;  2LWD A;  4P4H A;  4P4H I;  2MN4 A;  1A1W A;  4RHW E;  4JQW A;  2HM2 Q;  4D8O A;  3CL3 A;  2LWE A;  4DWN A;  4E9M A;  1Z6T A;  2P1H A;  1CWW A;  1N3K A;  3MOP A;  2MS7 A;  3YGS P;  1WXP A;  2YQF A;  4M9X A;  2YGS A;  2O71 A;  2D96 A;  1YGO A;  2DO9 A;  2N97 A;  3LQQ A;  2BBR A;  4ZBW A;  2DBG A;  4O6X A;  2N1F A;  1ICH A;  2MB9 A;  2A5Y B;  2GF5 A;  2A9I A;  4N1L A;  2OF5 H;  4IZ7 B;  3MOP G;  2KN6 A;  2F1S A;  2YVI A;  2B1W A;  2L6A A;  2XV9 A;  1D2Z B;  4O7Q A;  3T6P A;  1DGN A;  2MS8 A;  4A2Q A;  4I16 A;  1D2Z A;  4FH0 A;  4F42 A;  1WH4 A;  2NAQ A;  3MOP K;  2MJM A;  2N80 A;  2OF5 A;  4O9L A;  2MPC A;  2IB1 A;  2YU0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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