3F15A

Crystal structure of the catalytic domain of human mmp12 complexed with the inhibitor (s)-n-(2,3-dihydroxypropyl)-4-methoxy-n-(2-nitroso-2-oxoethyl)benzenesulfonamide
Total Genus 44
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
44
sequence length
158
structure length
158
Chain Sequence
GPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Exploring the subtleties of drug-receptor interactions: the case of matrix metalloproteinases.
pubmed doi rcsb
molecule keywords Macrophage metalloelastase
molecule tags Hydrolase
source organism Homo sapiens
total genus 44
structure length 158
sequence length 158
ec nomenclature ec 3.4.24.65: Macrophage elastase.
pdb deposition date 2008-10-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 3f15A00
1PWWA 4CTHA 3Q2HA 4JA1A 3MA2A 2OY2A 4AUOA 4ON1A 3K7NA 3P1VA 1JIZA 5I4OA 4FXQA 1GKDA 2AYKA 3L0TA 5L79A 4FXYP 4H2EA 3TT4A 1IAGA 2E3XA 2O3EA 2FV9A 1L6JA 4PKWA 1JAOA 2JNPA 2OVXA 3KMCA 1A85A 3F18A 2X3AA 3DPFA 1GKCA 4I03A 4XM8A 2POJA 2OXUA 3EHYA 4AXQA 1XFXA 4AYKA 2FV5A 1QIBA 2I47A 2DDYA 4XBHA 4DD8A 4H3XA 3EDHA 2CKIA 1AKLA 2TCLA 1R1JA 2J83A 5BPAA 2Y6CA 4H49A 4PKTA 3U1RA 2WOAA 1Y0VA 1HOVA 5D1SA 1B3DA 2DW1A 2XS4A 4WK7A 5D3CA 3AYKA 1BUVM 1XFVA 4DPEA 4WKEA 4H1QA 1K7GA 1YQYA 1MNCA 4GR3A 1I73A 1UEAA 3LILA 2RJPA 4HX3A 3HBUP 3EDZA 3B2ZA 1JIWP 5I3MA 5B5OA 5D1TA 3L0VA 1SMPA 4GR0A 1JAQA 4EFSA 1K7QA 1Q3AA 1D7XA 3DSLA 3USNA 2W13A 830CA 3EHXA 1R55A 1BKCE 1CIZA 2RJQA 3HY7A 4GQLA 1ASTA 4XM7A 4H84A 3E8RA 1H71P 2X3BA 1AF0A 1ZP5A 2OY4A 1ZTQA 2OW1A 3LMCA 1B8YA 2AIGP 1SLMA 2MZEA 1IACA 3G42A 1SU3A 1OM6A 5B5PA 4L19A 3ZXHA 1JH1A 3LQBA 5BOYA 2EROA 4WF6A 3TVCA 4GF1A 3EWJA 1D8MA 1KAPP 2L0RA 1RMZA 1XFWA 1CQRA 1Y93A 1KUGA 1EB6A 4H76A 1MMQA 4L6TA 1ND1A 1RM8A 4H30A 1OS2A 2Z2DA 1DTHA 5I0LA 1BKCA 2OXZA 1YCMA 1CGLA 1QUAA 3B8ZA 1CGEA 1BQOA 1C8TA 2XS3A 4A7BA 2K2GA 1MMRA 1QJJA 5LABA 1JANA 3ZUKA 2A8HA 3N2VA 1QJIA 4JP4A 3BA0A 2KRJA 5D1UA 4XM6A 2X3CA 2OZRA 2K9CA 3ZVSA 1MMPA 1CXVA 5I43A 4QKZA 4GUYA 3I7GA 1UTZA 1XFYA 3EDIA 2DDFA 3LEAA 1Y8JA 966CA 1BM6A 1OM7A 2OW2A 2YIGA 4PKUA 1IAEA 5H8XA 3LUMA 1G49A 1FM1A 3F15A 2Y6DA 3EDGA 3O64A 1WNIA 3OHLA 1R1HA 2SRTA 1YOUA 1CK7A 1KUHA 1PWPA 3GBOA 5I12A 1ROSA 4WKIA 5D7WA 4ZR5A 1JAPA 4GWNA 2W14A 3DWBA 2W12A 4IJOA 1EAKA 1C3IA 3DL1A 3AYUA 3LK8A 2DW0A 4AIGA 3KRYA 1D8FA 3TSKA 1K7IA 2PJTA 4JIJA 1I1IP 3LJZA 1G05A 1USNA 1CGFA 2MLRA 4I35A 1FBLA 3F17A 2OW0A 1EUBA 3I7IA 1G4KA 1GE5A 3K7LA 1HFSA 1HV5A 4FU4A 2WO8A 1BIWA 1UTTA 1G12A 4Q1LA 2ERPA 3CKIA 4JQGA 3F16A 1OS9A 4FVLA 5JMYA 3N2UA 1QIAA 3HDBA 3V96B 2N8RA 1ZXCA 2O36A 1PWUA 3TS4A 2V4BA 3F19A 2QPJA 1XUDA 3LQ0A 4PKVA 1BZSA 3KEKA 3KMEA 1HY7A 2JIHA 3WV2A 3LIRA 4DF9A 1UMTA 3LJTA 3VTGA 2JSDA 5CXAA 2W0DA 4IN9A 3VI1A 3G5CA 1ZXVA 2CLTA 1IABA 2OI0A 3KEJA 2DW2A 1GXDA 3KHIA 1KUKA 5I2ZA 5CZMA 3P24A 4WZVA 1DMTA 1BQQM 1FLSA 1IAAA 1HTDA 2MZIA 4H82A 1KUIA 1R54A 3DNGA 3KWVC 4R3VA 2OVZA 1A86A 3DPEA 2E2DA 3B92A 4IUWA 2J0TA 1C7KA 2X7MA 3HDAP 1PWVA 2JT6A 2HU6A 1R1IA 1XFUA 3O2XA 1XFZA 3HBVP 2JT5A 3AIGA 1PWQA 1JKYA 1XUCA 1YP1A 4G9LA 4A3WA 1SRPA 2USNA 3LIKA 3LKAA 1BUDA 3Q2GA 4PKQA 1S4BP 1XURA 1GO8P 3LUNA 2OW9A 3ELMA 1ATLA 1D5JA 3HY9A 3UVCA 3HYGA 1KUFA 1SLNA 4XCTA 2D1OA 5BOTA 4PKSA 2OXWA 4GR8A 1AYKA 2WO9A 1HFCA 4JPAA 2MZHA 2YB9A 1G9KA 5D2BA 3RTSA 5L7FA 4L63A 3LE9A 1JJ9A 1GE7A 4GWMA 4PKRA 1Z3JA 1ZVXA 3SHIA 3WV3A 1GO7P 3LJGA 456CA 1O0QA 3RTTA 4HMAA 4DV8A 2MLSA 3HB2P 1SATA 3NX7A 1BSWA 3LGPA 1ZS0A 1OMJA 1O0TA 3F1AA 1BKCI 4J4MA 1MMBA 5CUHA 1JK3A 3KECA 1KBCA 4G0DA 1IADA 1UMSA 1OM8A 3WV1A 1J7NA 2D1NA 1QICA 1CAQA 1GE6A 1I76A 2W15A 3OHOA 4ILWD 1OO9A 2ERQA
chains in the Genus database with same CATH superfamily
1PWWA 4CTHA 3Q2HA 4JA1A 3MA2A 2OY2A 4AUOA 4ON1A 3K7NA 3P1VA 1JIZA 5I4OA 4FXQA 1GKDA 2AYKA 3L0TA 4L7AA 5L79A 4FXYP 1TVIA 4H2EA 3TT4A 1IAGA 2E3XA 2O3EA 2FV9A 1L6JA 4PKWA 1JAOA 2JNPA 2OVXA 3KMCA 1A85A 3F18A 2X3AA 3DPFA 1GKCA 4I03A 4XM8A 2POJA 2OXUA 3EHYA 4AXQA 1XFXA 4AYKA 2FV5A 1QIBA 2I47A 2DDYA 4XBHA 4DD8A 4H3XA 3EDHA 2CKIA 1AKLA 2TCLA 1R1JA 2J83A 5BPAA 2Y6CA 4H49A 4PKTA 3U1RA 2WOAA 1Y0VA 1HOVA 5D1SA 1B3DA 2DW1A 2XS4A 4WK7A 5D3CA 3AYKA 1BUVM 1XFVA 4DPEA 4WKEA 4H1QA 1K7GA 1YQYA 1MNCA 4GR3A 1I73A 1UEAA 3LILA 2RJPA 4HX3A 3HBUP 3EDZA 3B2ZA 1JIWP 5I3MA 5B5OA 5D1TA 3L0VA 1SMPA 4GR0A 1JAQA 4EFSA 1K7QA 1Q3AA 1D7XA 3DSLA 3USNA 2W13A 830CA 3EHXA 1R55A 1BKCE 1CIZA 2RJQA 3HY7A 4GQLA 1ASTA 4XM7A 4H84A 3E8RA 1H71P 2X3BA 1OZ9A 1AF0A 1ZP5A 1XM5A 2OY4A 1ZTQA 2OW1A 3LMCA 1B8YA 2AIGP 1SLMA 2MZEA 3DTEA 1IACA 3G42A 1SU3A 1OM6A 5B5PA 4L19A 3ZXHA 1JH1A 3LQBA 5BOYA 2EROA 4WF6A 3TVCA 4GF1A 3EWJA 1D8MA 1KAPP 2L0RA 1RMZA 1XFWA 1CQRA 1Y93A 1KUGA 1EB6A 4H76A 1MMQA 4L6TA 1ND1A 1RM8A 4H30A 1OS2A 2Z2DA 1DTHA 5I0LA 1BKCA 2OXZA 1YCMA 1CGLA 1QUAA 3B8ZA 1CGEA 1BQOA 1C8TA 2XS3A 4A7BA 2K2GA 1MMRA 1QJJA 5LABA 1JANA 3ZUKA 2A8HA 3N2VA 1QJIA 4JP4A 3BA0A 2KRJA 5D1UA 4XM6A 2X3CA 2OZRA 2K9CA 3ZVSA 1MMPA 1CXVA 5I43A 4QKZA 4GUYA 3I7GA 1UTZA 1XFYA 3EDIA 2DDFA 3LEAA 1Y8JA 966CA 1BM6A 1OM7A 2OW2A 2YIGA 4PKUA 1IAEA 5H8XA 3LUMA 1G49A 1FM1A 3F15A 2Y6DA 3EDGA 3O64A 1WNIA 3OHLA 1R1HA 2SRTA 1YOUA 1CK7A 1KUHA 1PWPA 3GBOA 5I12A 1ROSA 4WKIA 5D7WA 4ZR5A 1JAPA 4GWNA 2W14A 3DWBA 2W12A 4IJOA 1EAKA 1C3IA 3DL1A 3AYUA 3LK8A 2DW0A 4AIGA 3KRYA 1D8FA 3TSKA 3DTKA 1K7IA 2PJTA 4JIJA 1I1IP 3LJZA 1G05A 1USNA 1CGFA 2MLRA 4I35A 1FBLA 3F17A 2OW0A 1EUBA 3I7IA 1G4KA 1GE5A 3K7LA 1HFSA 1HV5A 4FU4A 2WO8A 1BIWA 1UTTA 1G12A 4Q1LA 2ERPA 3CKIA 4JQGA 3F16A 1OS9A 4FVLA 5JMYA 3N2UA 1QIAA 2YUFA 3HDBA 3V96B 2N8RA 1ZXCA 2O36A 1PWUA 3TS4A 2V4BA 3F19A 2QPJA 1XUDA 3LQ0A 4PKVA 1BZSA 3KEKA 3KMEA 1HY7A 2JIHA 3WV2A 3LIRA 4DF9A 1UMTA 3LJTA 3VTGA 2JSDA 5CXAA 2W0DA 4IN9A 3VI1A 3G5CA 1ZXVA 2CLTA 1IABA 2OI0A 3KEJA 2DW2A 1GXDA 3KHIA 1XAXA 1KUKA 5I2ZA 5CZMA 3P24A 4WZVA 1DMTA 1BQQM 1FLSA 1IAAA 1HTDA 2MZIA 4H82A 1KUIA 1R54A 3DNGA 3KWVC 4R3VA 2OVZA 1A86A 3DPEA 2E2DA 3B92A 4IUWA 2J0TA 1C7KA 2X7MA 3HDAP 1PWVA 2JT6A 2HU6A 1R1IA 1XFUA 3O2XA 1XFZA 3HBVP 2JT5A 3AIGA 1PWQA 1JKYA 1XUCA 1YP1A 4G9LA 4A3WA 1SRPA 2USNA 3LIKA 3LKAA 1BUDA 3Q2GA 4PKQA 1S4BP 1XURA 1GO8P 3LUNA 2OW9A 3ELMA 1ATLA 1D5JA 3HY9A 3DTIA 3UVCA 3HYGA 1KUFA 1SLNA 4XCTA 2D1OA 5BOTA 4PKSA 2OXWA 4GR8A 1AYKA 2WO9A 1HFCA 4JPAA 2MZHA 2YB9A 1G9KA 5D2BA 3RTSA 5L7FA 4L63A 3LE9A 1JJ9A 1GE7A 4GWMA 4PKRA 1Z3JA 1ZVXA 3SHIA 3WV3A 1GO7P 3LJGA 456CA 1O0QA 3RTTA 4HMAA 4DV8A 2MLSA 3HB2P 1SATA 3NX7A 1BSWA 3LGPA 1ZS0A 1OMJA 1O0TA 3F1AA 1BKCI 4J4MA 1MMBA 5CUHA 1JK3A 3KECA 1KBCA 4G0DA 1IADA 1UMSA 1OM8A 3WV1A 1J7NA 2D1NA 1QICA 1CAQA 1GE6A 1I76A 2W15A 3OHOA 4ILWD 1OO9A 2ERQA
chains in the Genus database with same CATH topology
1PWWA 4CTHA 3Q2HA 4JA1A 3MA2A 2OY2A 4AUOA 4ON1A 3K7NA 3P1VA 1JIZA 5I4OA 4FXQA 1GKDA 2AYKA 3L0TA 4L7AA 5L79A 4FXYP 4H2EA 3TT4A 1IAGA 2E3XA 2O3EA 2FV9A 1L6JA 4PKWA 1JAOA 2JNPA 2OVXA 3KMCA 1A85A 3F18A 2X3AA 3DPFA 1GKCA 4I03A 4XM8A 2POJA 2OXUA 3EHYA 4AXQA 1XFXA 4AYKA 2FV5A 1QIBA 2I47A 2DDYA 4XBHA 4DD8A 4H3XA 3EDHA 2CKIA 1AKLA 2TCLA 1R1JA 2J83A 5BPAA 2Y6CA 4H49A 4PKTA 3U1RA 2WOAA 1Y0VA 1HOVA 5D1SA 1B3DA 2DW1A 2XS4A 4WK7A 5D3CA 3AYKA 1BUVM 1XFVA 4DPEA 4WKEA 4H1QA 1K7GA 1YQYA 1MNCA 4GR3A 1I73A 1UEAA 3LILA 2RJPA 4HX3A 3HBUP 3EDZA 3B2ZA 1JIWP 5I3MA 5B5OA 5D1TA 3L0VA 1SMPA 4GR0A 1JAQA 4EFSA 1K7QA 1Q3AA 1D7XA 3DSLA 3USNA 2W13A 830CA 3EHXA 1R55A 1BKCE 1CIZA 2RJQA 3HY7A 4GQLA 1ASTA 4XM7A 4H84A 3E8RA 1H71P 2X3BA 1AF0A 1ZP5A 2OY4A 1ZTQA 2OW1A 3LMCA 1B8YA 2AIGP 1SLMA 2MZEA 3DTEA 1IACA 3G42A 1SU3A 1OM6A 5B5PA 4L19A 3ZXHA 1JH1A 3LQBA 5BOYA 2EROA 4WF6A 3TVCA 4GF1A 3EWJA 1D8MA 1KAPP 2L0RA 1RMZA 1XFWA 1CQRA 1Y93A 1KUGA 1EB6A 4H76A 1MMQA 4L6TA 1ND1A 1RM8A 4H30A 1OS2A 2Z2DA 1DTHA 5I0LA 1BKCA 2OXZA 1YCMA 1CGLA 1QUAA 3B8ZA 1CGEA 1BQOA 1C8TA 2XS3A 4A7BA 2K2GA 1MMRA 1QJJA 5LABA 1JANA 3ZUKA 2A8HA 3N2VA 1QJIA 4JP4A 3BA0A 2KRJA 5D1UA 4XM6A 2X3CA 2OZRA 2K9CA 3ZVSA 1MMPA 1CXVA 5I43A 4QKZA 4GUYA 3I7GA 1UTZA 1XFYA 3EDIA 2DDFA 3LEAA 1Y8JA 966CA 1BM6A 1OM7A 2OW2A 2YIGA 4PKUA 1IAEA 5H8XA 3LUMA 1G49A 1FM1A 3F15A 2Y6DA 3EDGA 3O64A 1WNIA 3OHLA 1R1HA 2SRTA 1YOUA 1CK7A 1KUHA 1PWPA 3GBOA 5I12A 1ROSA 4WKIA 5D7WA 4ZR5A 1JAPA 4GWNA 2W14A 3DWBA 2W12A 4IJOA 1EAKA 1C3IA 3DL1A 3AYUA 3LK8A 2DW0A 4AIGA 3KRYA 1D8FA 3TSKA 3DTKA 1K7IA 2PJTA 4JIJA 1I1IP 3LJZA 1G05A 1USNA 1CGFA 2MLRA 4I35A 1FBLA 3F17A 2OW0A 1EUBA 3I7IA 1G4KA 1GE5A 3K7LA 1HFSA 1HV5A 4FU4A 2WO8A 1BIWA 1UTTA 1G12A 4Q1LA 2ERPA 3CKIA 4JQGA 3F16A 1OS9A 4FVLA 5JMYA 3N2UA 1QIAA 2YUFA 3HDBA 3V96B 2N8RA 1ZXCA 2O36A 1PWUA 3TS4A 2V4BA 3F19A 2QPJA 1XUDA 3LQ0A 4PKVA 1BZSA 3KEKA 3KMEA 1HY7A 2JIHA 3WV2A 3LIRA 4DF9A 1UMTA 3LJTA 3VTGA 2JSDA 5CXAA 2W0DA 4IN9A 3VI1A 3G5CA 1ZXVA 2CLTA 1IABA 2OI0A 3KEJA 2DW2A 1GXDA 3KHIA 1KUKA 5I2ZA 5CZMA 3P24A 4WZVA 1DMTA 1BQQM 1FLSA 1IAAA 1HTDA 2MZIA 4H82A 1KUIA 1R54A 3DNGA 3KWVC 4R3VA 2OVZA 1A86A 3DPEA 2E2DA 3B92A 4IUWA 2J0TA 1C7KA 2X7MA 3HDAP 1PWVA 2JT6A 2HU6A 1R1IA 1XFUA 3O2XA 1XFZA 3HBVP 2JT5A 3AIGA 1PWQA 1JKYA 1XUCA 1YP1A 4G9LA 4A3WA 1SRPA 2USNA 3LIKA 3LKAA 1BUDA 3Q2GA 4PKQA 1S4BP 1XURA 1GO8P 3LUNA 2OW9A 3ELMA 1ATLA 1D5JA 3HY9A 3DTIA 3UVCA 3HYGA 1KUFA 1SLNA 4XCTA 2D1OA 5BOTA 4PKSA 2OXWA 4GR8A 1AYKA 2WO9A 1HFCA 4JPAA 2MZHA 2YB9A 1G9KA 5D2BA 3RTSA 5L7FA 4L63A 3LE9A 1JJ9A 1GE7A 4GWMA 4PKRA 1Z3JA 1ZVXA 3SHIA 3WV3A 1GO7P 3LJGA 456CA 1O0QA 3RTTA 4HMAA 4DV8A 2MLSA 3HB2P 1SATA 3NX7A 1BSWA 3LGPA 1ZS0A 1OMJA 1O0TA 3F1AA 1BKCI 4J4MA 1MMBA 5CUHA 1JK3A 3KECA 1KBCA 4G0DA 1IADA 1UMSA 1OM8A 3WV1A 1J7NA 2D1NA 1QICA 1CAQA 1GE6A 1I76A 2W15A 3OHOA 4ILWD 1OO9A 2ERQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1PWW A;  4CTH A;  3Q2H A;  4JA1 A;  3MA2 A;  2OY2 A;  4AUO A;  4ON1 A;  3K7N A;  3P1V A;  1JIZ A;  5I4O A;  4FXQ A;  1GKD A;  2AYK A;  3L0T A;  5L79 A;  4FXY P;  4H2E A;  3TT4 A;  1IAG A;  2E3X A;  2O3E A;  2FV9 A;  1L6J A;  4PKW A;  1JAO A;  2JNP A;  2OVX A;  3KMC A;  1A85 A;  3F18 A;  2X3A A;  3DPF A;  1GKC A;  4I03 A;  4XM8 A;  2POJ A;  2OXU A;  3EHY A;  4AXQ A;  1XFX A;  4AYK A;  2FV5 A;  1QIB A;  2I47 A;  2DDY A;  4XBH A;  4DD8 A;  4H3X A;  3EDH A;  2CKI A;  1AKL A;  2TCL A;  1R1J A;  2J83 A;  5BPA A;  2Y6C A;  4H49 A;  4PKT A;  3U1R A;  2WOA A;  1Y0V A;  1HOV A;  5D1S A;  1B3D A;  2DW1 A;  2XS4 A;  4WK7 A;  5D3C A;  3AYK A;  1BUV M;  1XFV A;  4DPE A;  4WKE A;  4H1Q A;  1K7G A;  1YQY A;  1MNC A;  4GR3 A;  1I73 A;  1UEA A;  3LIL A;  2RJP A;  4HX3 A;  3HBU P;  3EDZ A;  3B2Z A;  1JIW P;  5I3M A;  5B5O A;  5D1T A;  3L0V A;  1SMP A;  4GR0 A;  1JAQ A;  4EFS A;  1K7Q A;  1Q3A A;  1D7X A;  3DSL A;  3USN A;  2W13 A;  830C A;  3EHX A;  1R55 A;  1BKC E;  1CIZ A;  2RJQ A;  3HY7 A;  4GQL A;  1AST A;  4XM7 A;  4H84 A;  3E8R A;  1H71 P;  2X3B A;  1AF0 A;  1ZP5 A;  2OY4 A;  1ZTQ A;  2OW1 A;  3LMC A;  1B8Y A;  2AIG P;  1SLM A;  2MZE A;  1IAC A;  3G42 A;  1SU3 A;  1OM6 A;  5B5P A;  4L19 A;  3ZXH A;  1JH1 A;  3LQB A;  5BOY A;  2ERO A;  4WF6 A;  3TVC A;  4GF1 A;  3EWJ A;  1D8M A;  1KAP P;  2L0R A;  1RMZ A;  1XFW A;  1CQR A;  1Y93 A;  1KUG A;  1EB6 A;  4H76 A;  1MMQ A;  4L6T A;  1ND1 A;  1RM8 A;  4H30 A;  1OS2 A;  2Z2D A;  1DTH A;  5I0L A;  1BKC A;  2OXZ A;  1YCM A;  1CGL A;  1QUA A;  3B8Z A;  1CGE A;  1BQO A;  1C8T A;  2XS3 A;  4A7B A;  2K2G A;  1MMR A;  1QJJ A;  5LAB A;  1JAN A;  3ZUK A;  2A8H A;  3N2V A;  1QJI A;  4JP4 A;  3BA0 A;  2KRJ A;  5D1U A;  4XM6 A;  2X3C A;  2OZR A;  2K9C A;  3ZVS A;  1MMP A;  1CXV A;  5I43 A;  4QKZ A;  4GUY A;  3I7G A;  1UTZ A;  1XFY A;  3EDI A;  2DDF A;  3LEA A;  1Y8J A;  966C A;  1BM6 A;  1OM7 A;  2OW2 A;  2YIG A;  4PKU A;  1IAE A;  5H8X A;  3LUM A;  1G49 A;  1FM1 A;  3F15 A;  2Y6D A;  3EDG A;  3O64 A;  1WNI A;  3OHL A;  1R1H A;  2SRT A;  1YOU A;  1CK7 A;  1KUH A;  1PWP A;  3GBO A;  5I12 A;  1ROS A;  4WKI A;  5D7W A;  4ZR5 A;  1JAP A;  4GWN A;  2W14 A;  3DWB A;  2W12 A;  4IJO A;  1EAK A;  1C3I A;  3DL1 A;  3AYU A;  3LK8 A;  2DW0 A;  4AIG A;  3KRY A;  1D8F A;  3TSK A;  1K7I A;  2PJT A;  4JIJ A;  1I1I P;  3LJZ A;  1G05 A;  1USN A;  1CGF A;  2MLR A;  4I35 A;  1FBL A;  3F17 A;  2OW0 A;  1EUB A;  3I7I A;  1G4K A;  1GE5 A;  3K7L A;  1HFS A;  1HV5 A;  4FU4 A;  2WO8 A;  1BIW A;  1UTT A;  1G12 A;  4Q1L A;  2ERP A;  3CKI A;  4JQG A;  3F16 A;  1OS9 A;  4FVL A;  5JMY A;  3N2U A;  1QIA A;  3HDB A;  3V96 B;  2N8R A;  1ZXC A;  2O36 A;  1PWU A;  3TS4 A;  2V4B A;  3F19 A;  2QPJ A;  1XUD A;  3LQ0 A;  4PKV A;  1BZS A;  3KEK A;  3KME A;  1HY7 A;  2JIH A;  3WV2 A;  3LIR A;  4DF9 A;  1UMT A;  3LJT A;  3VTG A;  2JSD A;  5CXA A;  2W0D A;  4IN9 A;  3VI1 A;  3G5C A;  1ZXV A;  2CLT A;  1IAB A;  2OI0 A;  3KEJ A;  2DW2 A;  1GXD A;  3KHI A;  1KUK A;  5I2Z A;  5CZM A;  3P24 A;  4WZV A;  1DMT A;  1BQQ M;  1FLS A;  1IAA A;  1HTD A;  2MZI A;  4H82 A;  1KUI A;  1R54 A;  3DNG A;  3KWV C;  4R3V A;  2OVZ A;  1A86 A;  3DPE A;  2E2D A;  3B92 A;  4IUW A;  2J0T A;  1C7K A;  2X7M A;  3HDA P;  1PWV A;  2JT6 A;  2HU6 A;  1R1I A;  1XFU A;  3O2X A;  1XFZ A;  3HBV P;  2JT5 A;  3AIG A;  1PWQ A;  1JKY A;  1XUC A;  1YP1 A;  4G9L A;  4A3W A;  1SRP A;  2USN A;  3LIK A;  3LKA A;  1BUD A;  3Q2G A;  4PKQ A;  1S4B P;  1XUR A;  1GO8 P;  3LUN A;  2OW9 A;  3ELM A;  1ATL A;  1D5J A;  3HY9 A;  3UVC A;  3HYG A;  1KUF A;  1SLN A;  4XCT A;  2D1O A;  5BOT A;  4PKS A;  2OXW A;  4GR8 A;  1AYK A;  2WO9 A;  1HFC A;  4JPA A;  2MZH A;  2YB9 A;  1G9K A;  5D2B A;  3RTS A;  5L7F A;  4L63 A;  3LE9 A;  1JJ9 A;  1GE7 A;  4GWM A;  4PKR A;  1Z3J A;  1ZVX A;  3SHI A;  3WV3 A;  1GO7 P;  3LJG A;  456C A;  1O0Q A;  3RTT A;  4HMA A;  4DV8 A;  2MLS A;  3HB2 P;  1SAT A;  3NX7 A;  1BSW A;  3LGP A;  1ZS0 A;  1OMJ A;  1O0T A;  3F1A A;  1BKC I;  4J4M A;  1MMB A;  5CUH A;  1JK3 A;  3KEC A;  1KBC A;  4G0D A;  1IAD A;  1UMS A;  1OM8 A;  3WV1 A;  1J7N A;  2D1N A;  1QIC A;  1CAQ A;  1GE6 A;  1I76 A;  2W15 A;  3OHO A;  4ILW D;  1OO9 A;  2ERQ A; 
#chains in the Genus database with same CATH topology
 1PWW A;  4CTH A;  3Q2H A;  4JA1 A;  3MA2 A;  2OY2 A;  4AUO A;  4ON1 A;  3K7N A;  3P1V A;  1JIZ A;  5I4O A;  4FXQ A;  1GKD A;  2AYK A;  3L0T A;  4L7A A;  5L79 A;  4FXY P;  1TVI A;  4H2E A;  3TT4 A;  1IAG A;  2E3X A;  2O3E A;  2FV9 A;  1L6J A;  4PKW A;  1JAO A;  2JNP A;  2OVX A;  3KMC A;  1A85 A;  3F18 A;  2X3A A;  3DPF A;  1GKC A;  4I03 A;  4XM8 A;  2POJ A;  2OXU A;  3EHY A;  4AXQ A;  1XFX A;  4AYK A;  2FV5 A;  1QIB A;  2I47 A;  2DDY A;  4XBH A;  4DD8 A;  4H3X A;  3EDH A;  2CKI A;  1AKL A;  2TCL A;  1R1J A;  2J83 A;  5BPA A;  2Y6C A;  4H49 A;  4PKT A;  3U1R A;  2WOA A;  1Y0V A;  1HOV A;  5D1S A;  1B3D A;  2DW1 A;  2XS4 A;  4WK7 A;  5D3C A;  3AYK A;  1BUV M;  1XFV A;  4DPE A;  4WKE A;  4H1Q A;  1K7G A;  1YQY A;  1MNC A;  4GR3 A;  1I73 A;  1UEA A;  3LIL A;  2RJP A;  4HX3 A;  3HBU P;  3EDZ A;  3B2Z A;  1JIW P;  5I3M A;  5B5O A;  5D1T A;  3L0V A;  1SMP A;  4GR0 A;  1JAQ A;  4EFS A;  1K7Q A;  1Q3A A;  1D7X A;  3DSL A;  3USN A;  2W13 A;  830C A;  3EHX A;  1R55 A;  1BKC E;  1CIZ A;  2RJQ A;  3HY7 A;  4GQL A;  1AST A;  4XM7 A;  4H84 A;  3E8R A;  1H71 P;  2X3B A;  1OZ9 A;  1AF0 A;  1ZP5 A;  1XM5 A;  2OY4 A;  1ZTQ A;  2OW1 A;  3LMC A;  1B8Y A;  2AIG P;  1SLM A;  2MZE A;  3DTE A;  1IAC A;  3G42 A;  1SU3 A;  1OM6 A;  5B5P A;  4L19 A;  3ZXH A;  1JH1 A;  3LQB A;  5BOY A;  2ERO A;  4WF6 A;  3TVC A;  4GF1 A;  3EWJ A;  1D8M A;  1KAP P;  2L0R A;  1RMZ A;  1XFW A;  1CQR A;  1Y93 A;  1KUG A;  1EB6 A;  4H76 A;  1MMQ A;  4L6T A;  1ND1 A;  1RM8 A;  4H30 A;  1OS2 A;  2Z2D A;  1DTH A;  5I0L A;  1BKC A;  2OXZ A;  1YCM A;  1CGL A;  1QUA A;  3B8Z A;  1CGE A;  1BQO A;  1C8T A;  2XS3 A;  4A7B A;  2K2G A;  1MMR A;  1QJJ A;  5LAB A;  1JAN A;  3ZUK A;  2A8H A;  3N2V A;  1QJI A;  4JP4 A;  3BA0 A;  2KRJ A;  5D1U A;  4XM6 A;  2X3C A;  2OZR A;  2K9C A;  3ZVS A;  1MMP A;  1CXV A;  5I43 A;  4QKZ A;  4GUY A;  3I7G A;  1UTZ A;  1XFY A;  3EDI A;  2DDF A;  3LEA A;  1Y8J A;  966C A;  1BM6 A;  1OM7 A;  2OW2 A;  2YIG A;  4PKU A;  1IAE A;  5H8X A;  3LUM A;  1G49 A;  1FM1 A;  3F15 A;  2Y6D A;  3EDG A;  3O64 A;  1WNI A;  3OHL A;  1R1H A;  2SRT A;  1YOU A;  1CK7 A;  1KUH A;  1PWP A;  3GBO A;  5I12 A;  1ROS A;  4WKI A;  5D7W A;  4ZR5 A;  1JAP A;  4GWN A;  2W14 A;  3DWB A;  2W12 A;  4IJO A;  1EAK A;  1C3I A;  3DL1 A;  3AYU A;  3LK8 A;  2DW0 A;  4AIG A;  3KRY A;  1D8F A;  3TSK A;  3DTK A;  1K7I A;  2PJT A;  4JIJ A;  1I1I P;  3LJZ A;  1G05 A;  1USN A;  1CGF A;  2MLR A;  4I35 A;  1FBL A;  3F17 A;  2OW0 A;  1EUB A;  3I7I A;  1G4K A;  1GE5 A;  3K7L A;  1HFS A;  1HV5 A;  4FU4 A;  2WO8 A;  1BIW A;  1UTT A;  1G12 A;  4Q1L A;  2ERP A;  3CKI A;  4JQG A;  3F16 A;  1OS9 A;  4FVL A;  5JMY A;  3N2U A;  1QIA A;  2YUF A;  3HDB A;  3V96 B;  2N8R A;  1ZXC A;  2O36 A;  1PWU A;  3TS4 A;  2V4B A;  3F19 A;  2QPJ A;  1XUD A;  3LQ0 A;  4PKV A;  1BZS A;  3KEK A;  3KME A;  1HY7 A;  2JIH A;  3WV2 A;  3LIR A;  4DF9 A;  1UMT A;  3LJT A;  3VTG A;  2JSD A;  5CXA A;  2W0D A;  4IN9 A;  3VI1 A;  3G5C A;  1ZXV A;  2CLT A;  1IAB A;  2OI0 A;  3KEJ A;  2DW2 A;  1GXD A;  3KHI A;  1XAX A;  1KUK A;  5I2Z A;  5CZM A;  3P24 A;  4WZV A;  1DMT A;  1BQQ M;  1FLS A;  1IAA A;  1HTD A;  2MZI A;  4H82 A;  1KUI A;  1R54 A;  3DNG A;  3KWV C;  4R3V A;  2OVZ A;  1A86 A;  3DPE A;  2E2D A;  3B92 A;  4IUW A;  2J0T A;  1C7K A;  2X7M A;  3HDA P;  1PWV A;  2JT6 A;  2HU6 A;  1R1I A;  1XFU A;  3O2X A;  1XFZ A;  3HBV P;  2JT5 A;  3AIG A;  1PWQ A;  1JKY A;  1XUC A;  1YP1 A;  4G9L A;  4A3W A;  1SRP A;  2USN A;  3LIK A;  3LKA A;  1BUD A;  3Q2G A;  4PKQ A;  1S4B P;  1XUR A;  1GO8 P;  3LUN A;  2OW9 A;  3ELM A;  1ATL A;  1D5J A;  3HY9 A;  3DTI A;  3UVC A;  3HYG A;  1KUF A;  1SLN A;  4XCT A;  2D1O A;  5BOT A;  4PKS A;  2OXW A;  4GR8 A;  1AYK A;  2WO9 A;  1HFC A;  4JPA A;  2MZH A;  2YB9 A;  1G9K A;  5D2B A;  3RTS A;  5L7F A;  4L63 A;  3LE9 A;  1JJ9 A;  1GE7 A;  4GWM A;  4PKR A;  1Z3J A;  1ZVX A;  3SHI A;  3WV3 A;  1GO7 P;  3LJG A;  456C A;  1O0Q A;  3RTT A;  4HMA A;  4DV8 A;  2MLS A;  3HB2 P;  1SAT A;  3NX7 A;  1BSW A;  3LGP A;  1ZS0 A;  1OMJ A;  1O0T A;  3F1A A;  1BKC I;  4J4M A;  1MMB A;  5CUH A;  1JK3 A;  3KEC A;  1KBC A;  4G0D A;  1IAD A;  1UMS A;  1OM8 A;  3WV1 A;  1J7N A;  2D1N A;  1QIC A;  1CAQ A;  1GE6 A;  1I76 A;  2W15 A;  3OHO A;  4ILW D;  1OO9 A;  2ERQ A; 
#chains in the Genus database with same CATH homology
 1PWW A;  4CTH A;  3Q2H A;  4JA1 A;  3MA2 A;  2OY2 A;  4AUO A;  4ON1 A;  3K7N A;  3P1V A;  1JIZ A;  5I4O A;  4FXQ A;  1GKD A;  2AYK A;  3L0T A;  4L7A A;  5L79 A;  4FXY P;  4H2E A;  3TT4 A;  1IAG A;  2E3X A;  2O3E A;  2FV9 A;  1L6J A;  4PKW A;  1JAO A;  2JNP A;  2OVX A;  3KMC A;  1A85 A;  3F18 A;  2X3A A;  3DPF A;  1GKC A;  4I03 A;  4XM8 A;  2POJ A;  2OXU A;  3EHY A;  4AXQ A;  1XFX A;  4AYK A;  2FV5 A;  1QIB A;  2I47 A;  2DDY A;  4XBH A;  4DD8 A;  4H3X A;  3EDH A;  2CKI A;  1AKL A;  2TCL A;  1R1J A;  2J83 A;  5BPA A;  2Y6C A;  4H49 A;  4PKT A;  3U1R A;  2WOA A;  1Y0V A;  1HOV A;  5D1S A;  1B3D A;  2DW1 A;  2XS4 A;  4WK7 A;  5D3C A;  3AYK A;  1BUV M;  1XFV A;  4DPE A;  4WKE A;  4H1Q A;  1K7G A;  1YQY A;  1MNC A;  4GR3 A;  1I73 A;  1UEA A;  3LIL A;  2RJP A;  4HX3 A;  3HBU P;  3EDZ A;  3B2Z A;  1JIW P;  5I3M A;  5B5O A;  5D1T A;  3L0V A;  1SMP A;  4GR0 A;  1JAQ A;  4EFS A;  1K7Q A;  1Q3A A;  1D7X A;  3DSL A;  3USN A;  2W13 A;  830C A;  3EHX A;  1R55 A;  1BKC E;  1CIZ A;  2RJQ A;  3HY7 A;  4GQL A;  1AST A;  4XM7 A;  4H84 A;  3E8R A;  1H71 P;  2X3B A;  1AF0 A;  1ZP5 A;  2OY4 A;  1ZTQ A;  2OW1 A;  3LMC A;  1B8Y A;  2AIG P;  1SLM A;  2MZE A;  3DTE A;  1IAC A;  3G42 A;  1SU3 A;  1OM6 A;  5B5P A;  4L19 A;  3ZXH A;  1JH1 A;  3LQB A;  5BOY A;  2ERO A;  4WF6 A;  3TVC A;  4GF1 A;  3EWJ A;  1D8M A;  1KAP P;  2L0R A;  1RMZ A;  1XFW A;  1CQR A;  1Y93 A;  1KUG A;  1EB6 A;  4H76 A;  1MMQ A;  4L6T A;  1ND1 A;  1RM8 A;  4H30 A;  1OS2 A;  2Z2D A;  1DTH A;  5I0L A;  1BKC A;  2OXZ A;  1YCM A;  1CGL A;  1QUA A;  3B8Z A;  1CGE A;  1BQO A;  1C8T A;  2XS3 A;  4A7B A;  2K2G A;  1MMR A;  1QJJ A;  5LAB A;  1JAN A;  3ZUK A;  2A8H A;  3N2V A;  1QJI A;  4JP4 A;  3BA0 A;  2KRJ A;  5D1U A;  4XM6 A;  2X3C A;  2OZR A;  2K9C A;  3ZVS A;  1MMP A;  1CXV A;  5I43 A;  4QKZ A;  4GUY A;  3I7G A;  1UTZ A;  1XFY A;  3EDI A;  2DDF A;  3LEA A;  1Y8J A;  966C A;  1BM6 A;  1OM7 A;  2OW2 A;  2YIG A;  4PKU A;  1IAE A;  5H8X A;  3LUM A;  1G49 A;  1FM1 A;  3F15 A;  2Y6D A;  3EDG A;  3O64 A;  1WNI A;  3OHL A;  1R1H A;  2SRT A;  1YOU A;  1CK7 A;  1KUH A;  1PWP A;  3GBO A;  5I12 A;  1ROS A;  4WKI A;  5D7W A;  4ZR5 A;  1JAP A;  4GWN A;  2W14 A;  3DWB A;  2W12 A;  4IJO A;  1EAK A;  1C3I A;  3DL1 A;  3AYU A;  3LK8 A;  2DW0 A;  4AIG A;  3KRY A;  1D8F A;  3TSK A;  3DTK A;  1K7I A;  2PJT A;  4JIJ A;  1I1I P;  3LJZ A;  1G05 A;  1USN A;  1CGF A;  2MLR A;  4I35 A;  1FBL A;  3F17 A;  2OW0 A;  1EUB A;  3I7I A;  1G4K A;  1GE5 A;  3K7L A;  1HFS A;  1HV5 A;  4FU4 A;  2WO8 A;  1BIW A;  1UTT A;  1G12 A;  4Q1L A;  2ERP A;  3CKI A;  4JQG A;  3F16 A;  1OS9 A;  4FVL A;  5JMY A;  3N2U A;  1QIA A;  2YUF A;  3HDB A;  3V96 B;  2N8R A;  1ZXC A;  2O36 A;  1PWU A;  3TS4 A;  2V4B A;  3F19 A;  2QPJ A;  1XUD A;  3LQ0 A;  4PKV A;  1BZS A;  3KEK A;  3KME A;  1HY7 A;  2JIH A;  3WV2 A;  3LIR A;  4DF9 A;  1UMT A;  3LJT A;  3VTG A;  2JSD A;  5CXA A;  2W0D A;  4IN9 A;  3VI1 A;  3G5C A;  1ZXV A;  2CLT A;  1IAB A;  2OI0 A;  3KEJ A;  2DW2 A;  1GXD A;  3KHI A;  1KUK A;  5I2Z A;  5CZM A;  3P24 A;  4WZV A;  1DMT A;  1BQQ M;  1FLS A;  1IAA A;  1HTD A;  2MZI A;  4H82 A;  1KUI A;  1R54 A;  3DNG A;  3KWV C;  4R3V A;  2OVZ A;  1A86 A;  3DPE A;  2E2D A;  3B92 A;  4IUW A;  2J0T A;  1C7K A;  2X7M A;  3HDA P;  1PWV A;  2JT6 A;  2HU6 A;  1R1I A;  1XFU A;  3O2X A;  1XFZ A;  3HBV P;  2JT5 A;  3AIG A;  1PWQ A;  1JKY A;  1XUC A;  1YP1 A;  4G9L A;  4A3W A;  1SRP A;  2USN A;  3LIK A;  3LKA A;  1BUD A;  3Q2G A;  4PKQ A;  1S4B P;  1XUR A;  1GO8 P;  3LUN A;  2OW9 A;  3ELM A;  1ATL A;  1D5J A;  3HY9 A;  3DTI A;  3UVC A;  3HYG A;  1KUF A;  1SLN A;  4XCT A;  2D1O A;  5BOT A;  4PKS A;  2OXW A;  4GR8 A;  1AYK A;  2WO9 A;  1HFC A;  4JPA A;  2MZH A;  2YB9 A;  1G9K A;  5D2B A;  3RTS A;  5L7F A;  4L63 A;  3LE9 A;  1JJ9 A;  1GE7 A;  4GWM A;  4PKR A;  1Z3J A;  1ZVX A;  3SHI A;  3WV3 A;  1GO7 P;  3LJG A;  456C A;  1O0Q A;  3RTT A;  4HMA A;  4DV8 A;  2MLS A;  3HB2 P;  1SAT A;  3NX7 A;  1BSW A;  3LGP A;  1ZS0 A;  1OMJ A;  1O0T A;  3F1A A;  1BKC I;  4J4M A;  1MMB A;  5CUH A;  1JK3 A;  3KEC A;  1KBC A;  4G0D A;  1IAD A;  1UMS A;  1OM8 A;  3WV1 A;  1J7N A;  2D1N A;  1QIC A;  1CAQ A;  1GE6 A;  1I76 A;  2W15 A;  3OHO A;  4ILW D;  1OO9 A;  2ERQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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