3F16A

Crystal structure of the catalytic domain of human mmp12 complexed with the inhibitor (r)-n-(3-hydroxy-1-nitroso-1-oxopropan-2-yl)-4-methoxybenzenesulfonamide
Total Genus 43
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
43
sequence length
158
structure length
158
Chain Sequence
GPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Exploring the subtleties of drug-receptor interactions: the case of matrix metalloproteinases.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Macrophage metalloelastase
total genus 43
structure length 158
sequence length 158
ec nomenclature ec 3.4.24.65: Macrophage elastase.
pdb deposition date 2008-10-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 3f16A00
2RJPA 3K7NA 1QJIA 1BM6A 2X3AA 3EDIA 1GE6A 4GWNA 1MMQA 4G9LA 4G0DA 3P1VA 2POJA 456CA 2OY4A 3HBUP 3TSKA 1B3DA 3KRYA 1CXVA 1Y93A 1HV5A 2AIGP 1CGEA 1SRPA 3B8ZA 1I73A 2HU6A 1G05A 1XUCA 4GR3A 3F18A 1RM8A 1FM1A 2Z2DA 3LIRA 1K7QA 2WO8A 3KEKA 4J4MA 1ROSA 2WO9A 4PKSA 4XM8A 1GO7P 3LIKA 1O0TA 4HX3A 1Y8JA 4R3VA 1PWQA 4GQLA 4XM6A 1JANA 1G9KA 1ZXVA 4AUOA 1ATLA 1OS2A 1EUBA 1KAPP 1OM6A 2KRJA 4JIJA 5I4OA 4DV8A 4AIGA 2DW2A 1EB6A 4FVLA 1BKCA 1K7IA 2J83A 3LJTA 3L0VA 1KUHA 1BUVM 2D1OA 3Q2HA 1PWPA 1ZP5A 1K7GA 3I7IA 3MA2A 1UEAA 2X3CA 3OHLA 4GWMA 4IN9A 3ZUKA 2OXWA 1QJJA 3BA0A 1SMPA 5D1SA 1BQQM 4XM7A 3WV1A 1CIZA 2OY2A 2A8HA 1ZTQA 1QICA 3HY9A 4XBHA 2MZHA 3EDGA 5D1TA 2RJQA 1JKYA 1DMTA 3EWJA 2E2DA 2OXUA 2FV9A 1Z3JA 1GKDA 2W13A 1YQYA 1ZVXA 4H82A 1C3IA 3SHIA 4H84A 1R54A 3UVCA 1G12A 5BOTA 3TVCA 4FU4A 1USNA 1GKCA 1B8YA 1JIWP 1R55A 4JQGA 2SRTA 1D8FA 1I1IP 1QUAA 2DW1A 3F15A 2DW0A 3CKIA 5CUHA 1KUFA 1JAQA 3LGPA 2OXZA 3F19A 5I3MA 1ASTA 2JT5A 4I03A 2N8RA 1BQOA 4IUWA 3ZVSA 3EDZA 4DPEA 2JT6A 3DPFA 966CA 4IJOA 2L0RA 3P24A 2YIGA 1OO9A 1QIAA 3DWBA 1JJ9A 5D3CA 4FXYP 830CA 4DF9A 1HY7A 2OW2A 4PKQA 2OI0A 3F1AA 2X3BA 1MMRA 1GXDA 1JH1A 1SLNA 3DPEA 4Q1LA 1OM7A 1XFVA 2OVZA 2MLSA 4PKTA 1Q3AA 4H30A 2OZRA 1D7XA 2OW0A 3EHYA 4CTHA 4QKZA 2ERQA 1XFXA 1I76A 1IAGA 2O36A 1ND1A 3LUNA 1PWUA 1A85A 1BUDA 2XS4A 2W0DA 1BZSA 2JNPA 1CGFA 3Q2GA 3RTSA 3EHXA 5JMYA 1MNCA 1HFCA 1JIZA 2TCLA 2O3EA 2MZEA 2WOAA 2W15A 2E3XA 4WF6A 1ZS0A 2DDFA 1HTDA 3OHOA 1JK3A 1L6JA 1CK7A 3WV3A 3DSLA 1OMJA 1R1JA 3F17A 1SU3A 3KWVC 4JP4A 3LKAA 2OVXA 3AYKA 1CGLA 3GBOA 1YP1A 1UTZA 3VI1A 1AF0A 3LMCA 2D1NA 1AKLA 1MMBA 1O0QA 3KMEA 2EROA 4L63A 2W14A 3AIGA 3I7GA 3N2UA 2AYKA 3HDBA 1KUIA 1PWWA 1ZXCA 1XUDA 3TT4A 1D8MA 1JAPA 2V4BA 1XFUA 1HFSA 4FXQA 4ON1A 1FBLA 3WV2A 4GR0A 4WZVA 3DNGA 1D5JA 1Y0VA 1RMZA 5I12A 1WNIA 1GE5A 2JSDA 3USNA 5BPAA 2QPJA 2J0TA 2MZIA 4WKIA 4H76A 3LJGA 1BIWA 1BKCE 1H71P 1A86A 1XFWA 5B5PA 1C8TA 2I47A 1CQRA 2CKIA 3ZXHA 3LUMA 4PKUA 4AYKA 3RTTA 4H1QA 4JPAA 1HOVA 1SATA 4ZR5A 1QIBA 5B5OA 2K2GA 4A3WA 3HYGA 1CAQA 1XFZA 2Y6CA 3HDAP 2CLTA 3K7LA 4PKWA 1G49A 2ERPA 2JIHA 5LABA 1S4BP 4ILWD 3TS4A 1BKCI 4GF1A 4GR8A 4PKVA 3NX7A 4L6TA 4PKRA 4WKEA 3LK8A 3LILA 1OS9A 1KBCA 3O64A 1PWVA 3HY7A 3G5CA 5I43A 1MMPA 1R1IA 3VTGA 3LJZA 4H49A 3V96B 3LE9A 5D7WA 3LQ0A 1XURA 2PJTA 3N2VA 3G42A 3F16A 4EFSA 3DL1A 1YCMA 4A7BA 3LQBA 1GO8P 3KEJA 2X7MA 2K9CA 1AYKA 4DD8A 4WK7A 1G4KA 4XCTA 1UMTA 1FLSA 3AYUA 1R1HA 1UTTA 5D1UA 1YOUA 3L0TA 1IABA 1JAOA 2MLRA 3KMCA 5L7FA 3O2XA 1C7KA 2W12A 3B92A 1DTHA 2USNA 3LEAA 1J7NA 3HB2P 2DDYA 5CZMA 2XS3A 4GUYA 4I35A 1IAEA 3KHIA 5I0LA 1KUGA 2YB9A 4H3XA 1OM8A 1KUKA 2Y6DA 1XFYA 1IACA 3EDHA 5I2ZA 5BOYA 1UMSA 4AXQA 1EAKA 3KECA 4JA1A 5L79A 3B2ZA 4H2EA 2FV5A 2OW1A 3E8RA 3U1RA 3ELMA 3HBVP 2OW9A 4L19A 1IADA 1IAAA 1SLMA 5H8XA 4HMAA 1GE7A 1BSWA 5D2BA 5CXAA
chains in the Genus database with same CATH superfamily
2RJPA 3K7NA 1QJIA 1BM6A 2X3AA 3EDIA 1GE6A 4GWNA 1MMQA 4G9LA 4G0DA 3P1VA 2POJA 456CA 2OY4A 3HBUP 3TSKA 1B3DA 3KRYA 1CXVA 1Y93A 1HV5A 2AIGP 1CGEA 1SRPA 3B8ZA 1I73A 2HU6A 1G05A 1XUCA 4GR3A 3F18A 1RM8A 1FM1A 2Z2DA 3LIRA 1K7QA 2WO8A 3KEKA 4J4MA 1ROSA 2WO9A 4PKSA 4XM8A 1GO7P 3LIKA 1O0TA 4HX3A 1Y8JA 4R3VA 1PWQA 4GQLA 4XM6A 1JANA 1G9KA 1ZXVA 4AUOA 1ATLA 1OS2A 1TVIA 1KAPP 1OM6A 2KRJA 1EUBA 4JIJA 5I4OA 4DV8A 4AIGA 2DW2A 1EB6A 4FVLA 1BKCA 1K7IA 2J83A 3LJTA 3L0VA 3DTKA 1KUHA 1BUVM 2D1OA 3Q2HA 1PWPA 1ZP5A 1K7GA 3I7IA 3MA2A 4L7AA 1UEAA 2X3CA 3OHLA 4GWMA 4IN9A 3ZUKA 2OXWA 1QJJA 3BA0A 1SMPA 5D1SA 1BQQM 4XM7A 3WV1A 1CIZA 2OY2A 2A8HA 1ZTQA 1QICA 3HY9A 4XBHA 2MZHA 3EDGA 5D1TA 2RJQA 3DTIA 1JKYA 1DMTA 3EWJA 2E2DA 2OXUA 2FV9A 1Z3JA 1GKDA 2W13A 1YQYA 1ZVXA 4H82A 1C3IA 3SHIA 4H84A 1R54A 3UVCA 1G12A 5BOTA 3TVCA 4FU4A 1USNA 1GKCA 1B8YA 1JIWP 1R55A 4JQGA 2SRTA 1D8FA 1I1IP 1QUAA 2DW1A 3F15A 2DW0A 3CKIA 5CUHA 1KUFA 1JAQA 3LGPA 2OXZA 3F19A 5I3MA 1ASTA 2JT5A 4I03A 2N8RA 1BQOA 4IUWA 3ZVSA 3EDZA 4DPEA 2JT6A 3DPFA 966CA 4IJOA 2L0RA 3P24A 2YIGA 1OO9A 1QIAA 3DWBA 1JJ9A 5D3CA 4FXYP 830CA 4DF9A 1HY7A 2OW2A 4PKQA 2OI0A 3F1AA 2X3BA 1MMRA 1GXDA 1JH1A 1SLNA 3DPEA 4Q1LA 1OM7A 1XFVA 2OVZA 2MLSA 4PKTA 1Q3AA 4H30A 2OZRA 1D7XA 2OW0A 3EHYA 4CTHA 4QKZA 2ERQA 1XFXA 1I76A 1IAGA 2O36A 1ND1A 3LUNA 1PWUA 1A85A 1BUDA 2XS4A 2W0DA 1BZSA 2JNPA 1CGFA 3Q2GA 3RTSA 3EHXA 5JMYA 1MNCA 1HFCA 1JIZA 2TCLA 2O3EA 2MZEA 2WOAA 2W15A 2E3XA 4WF6A 1ZS0A 2DDFA 1HTDA 3OHOA 1JK3A 1L6JA 1CK7A 3WV3A 3DSLA 1OMJA 1R1JA 3F17A 1SU3A 3KWVC 4JP4A 3LKAA 2OVXA 3AYKA 1CGLA 3GBOA 1YP1A 1UTZA 3VI1A 1AF0A 1XM5A 3LMCA 2D1NA 1AKLA 1MMBA 1O0QA 3KMEA 2EROA 4L63A 2W14A 3AIGA 3I7GA 3N2UA 2AYKA 3HDBA 1KUIA 1PWWA 1ZXCA 1XUDA 3TT4A 1D8MA 1JAPA 2V4BA 1XFUA 1HFSA 4FXQA 4ON1A 1FBLA 3WV2A 4GR0A 4WZVA 3DNGA 1D5JA 1Y0VA 1RMZA 5I12A 1WNIA 1GE5A 2JSDA 3USNA 5BPAA 2QPJA 2J0TA 2MZIA 4WKIA 4H76A 3LJGA 1BIWA 1BKCE 1H71P 1A86A 1XFWA 5B5PA 1C8TA 2I47A 1CQRA 2CKIA 3ZXHA 2YUFA 3LUMA 4PKUA 4AYKA 3RTTA 4H1QA 4JPAA 1HOVA 1SATA 4ZR5A 1QIBA 1OZ9A 5B5OA 2K2GA 4A3WA 3HYGA 1CAQA 1XFZA 2Y6CA 3HDAP 1XAXA 2CLTA 3K7LA 4PKWA 1G49A 2ERPA 2JIHA 5LABA 1S4BP 4ILWD 3TS4A 1BKCI 4GF1A 4GR8A 4PKVA 3NX7A 4L6TA 4PKRA 4WKEA 3LK8A 3LILA 1OS9A 1KBCA 3O64A 1PWVA 3HY7A 3G5CA 5I43A 1MMPA 1R1IA 3VTGA 3LJZA 4H49A 3V96B 3LE9A 5D7WA 3LQ0A 1XURA 2PJTA 3N2VA 3G42A 3F16A 4EFSA 3DL1A 1YCMA 4A7BA 3LQBA 1GO8P 3KEJA 2X7MA 2K9CA 1AYKA 4DD8A 4WK7A 1G4KA 4XCTA 1UMTA 1FLSA 3AYUA 1R1HA 1UTTA 5D1UA 1YOUA 3L0TA 1IABA 1JAOA 2MLRA 3KMCA 5L7FA 3O2XA 1C7KA 2W12A 3B92A 1DTHA 2USNA 3LEAA 1J7NA 3HB2P 2DDYA 5CZMA 2XS3A 4GUYA 4I35A 1IAEA 3KHIA 5I0LA 3DTEA 1KUGA 2YB9A 4H3XA 1OM8A 1KUKA 2Y6DA 1XFYA 1IACA 3EDHA 5I2ZA 5BOYA 1UMSA 4AXQA 1EAKA 3KECA 4JA1A 5L79A 3B2ZA 4H2EA 2FV5A 2OW1A 3E8RA 3U1RA 3ELMA 3HBVP 2OW9A 4L19A 1IADA 1IAAA 1SLMA 5H8XA 4HMAA 1GE7A 1BSWA 5D2BA 5CXAA
chains in the Genus database with same CATH topology
2RJPA 3K7NA 1QJIA 1BM6A 2X3AA 3EDIA 1GE6A 4GWNA 1MMQA 4G9LA 4G0DA 3P1VA 2POJA 456CA 2OY4A 3HBUP 3TSKA 1B3DA 3KRYA 1CXVA 1Y93A 1HV5A 2AIGP 1CGEA 1SRPA 3B8ZA 1I73A 2HU6A 1G05A 1XUCA 4GR3A 3F18A 1RM8A 1FM1A 2Z2DA 3LIRA 1K7QA 2WO8A 3KEKA 4J4MA 1ROSA 2WO9A 4PKSA 4XM8A 1GO7P 3LIKA 1O0TA 4HX3A 1Y8JA 4R3VA 1PWQA 4GQLA 4XM6A 1JANA 1G9KA 1ZXVA 4AUOA 1ATLA 1OS2A 1EUBA 1KAPP 1OM6A 2KRJA 4JIJA 5I4OA 4DV8A 4AIGA 2DW2A 1EB6A 4FVLA 1BKCA 1K7IA 2J83A 3LJTA 3L0VA 3DTKA 1KUHA 1BUVM 2D1OA 3Q2HA 1PWPA 1ZP5A 1K7GA 3I7IA 3MA2A 4L7AA 1UEAA 2X3CA 3OHLA 4GWMA 4IN9A 3ZUKA 2OXWA 1QJJA 3BA0A 1SMPA 5D1SA 1BQQM 4XM7A 3WV1A 1CIZA 2OY2A 2A8HA 1ZTQA 1QICA 3HY9A 4XBHA 2MZHA 3EDGA 5D1TA 2RJQA 3DTIA 1JKYA 1DMTA 3EWJA 2E2DA 2OXUA 2FV9A 1Z3JA 1GKDA 2W13A 1YQYA 1ZVXA 4H82A 1C3IA 3SHIA 4H84A 1R54A 3UVCA 1G12A 5BOTA 3TVCA 4FU4A 1USNA 1GKCA 1B8YA 1JIWP 1R55A 4JQGA 2SRTA 1D8FA 1I1IP 1QUAA 2DW1A 3F15A 2DW0A 3CKIA 5CUHA 1KUFA 1JAQA 3LGPA 2OXZA 3F19A 5I3MA 1ASTA 2JT5A 4I03A 2N8RA 1BQOA 4IUWA 3ZVSA 3EDZA 4DPEA 2JT6A 3DPFA 966CA 4IJOA 2L0RA 3P24A 2YIGA 1OO9A 1QIAA 3DWBA 1JJ9A 5D3CA 4FXYP 830CA 4DF9A 1HY7A 2OW2A 4PKQA 2OI0A 3F1AA 2X3BA 1MMRA 1GXDA 1JH1A 1SLNA 3DPEA 4Q1LA 1OM7A 1XFVA 2OVZA 2MLSA 4PKTA 1Q3AA 4H30A 2OZRA 1D7XA 2OW0A 3EHYA 4CTHA 4QKZA 2ERQA 1XFXA 1I76A 1IAGA 2O36A 1ND1A 3LUNA 1PWUA 1A85A 1BUDA 2XS4A 2W0DA 1BZSA 2JNPA 1CGFA 3Q2GA 3RTSA 3EHXA 5JMYA 1MNCA 1HFCA 1JIZA 2TCLA 2O3EA 2MZEA 2WOAA 2W15A 2E3XA 4WF6A 1ZS0A 2DDFA 1HTDA 3OHOA 1JK3A 1L6JA 1CK7A 3WV3A 3DSLA 1OMJA 1R1JA 3F17A 1SU3A 3KWVC 4JP4A 3LKAA 2OVXA 3AYKA 1CGLA 3GBOA 1YP1A 1UTZA 3VI1A 1AF0A 3LMCA 2D1NA 1AKLA 1MMBA 1O0QA 3KMEA 2EROA 4L63A 2W14A 3AIGA 3I7GA 3N2UA 2AYKA 3HDBA 1KUIA 1PWWA 1ZXCA 1XUDA 3TT4A 1D8MA 1JAPA 2V4BA 1XFUA 1HFSA 4FXQA 4ON1A 1FBLA 3WV2A 4GR0A 4WZVA 3DNGA 1D5JA 1Y0VA 1RMZA 5I12A 1WNIA 1GE5A 2JSDA 3USNA 5BPAA 2QPJA 2J0TA 2MZIA 4WKIA 4H76A 3LJGA 1BIWA 1BKCE 1H71P 1A86A 1XFWA 5B5PA 1C8TA 2I47A 1CQRA 2CKIA 3ZXHA 2YUFA 3LUMA 4PKUA 4AYKA 3RTTA 4H1QA 4JPAA 1HOVA 1SATA 4ZR5A 1QIBA 5B5OA 2K2GA 4A3WA 3HYGA 1CAQA 1XFZA 2Y6CA 3HDAP 2CLTA 3K7LA 4PKWA 1G49A 2ERPA 2JIHA 5LABA 1S4BP 4ILWD 3TS4A 1BKCI 4GF1A 4GR8A 4PKVA 3NX7A 4L6TA 4PKRA 4WKEA 3LK8A 3LILA 1OS9A 1KBCA 3O64A 1PWVA 3HY7A 3G5CA 5I43A 1MMPA 1R1IA 3VTGA 3LJZA 4H49A 3V96B 3LE9A 5D7WA 3LQ0A 1XURA 2PJTA 3N2VA 3G42A 3F16A 4EFSA 3DL1A 1YCMA 4A7BA 3LQBA 1GO8P 3KEJA 2X7MA 2K9CA 1AYKA 4DD8A 4WK7A 1G4KA 4XCTA 1UMTA 1FLSA 3AYUA 1R1HA 1UTTA 5D1UA 1YOUA 3L0TA 1IABA 1JAOA 2MLRA 3KMCA 5L7FA 3O2XA 1C7KA 2W12A 3B92A 1DTHA 2USNA 3LEAA 1J7NA 3HB2P 2DDYA 5CZMA 2XS3A 4GUYA 4I35A 1IAEA 3KHIA 5I0LA 3DTEA 1KUGA 2YB9A 4H3XA 1OM8A 1KUKA 2Y6DA 1XFYA 1IACA 3EDHA 5I2ZA 5BOYA 1UMSA 4AXQA 1EAKA 3KECA 4JA1A 5L79A 3B2ZA 4H2EA 2FV5A 2OW1A 3E8RA 3U1RA 3ELMA 3HBVP 2OW9A 4L19A 1IADA 1IAAA 1SLMA 5H8XA 4HMAA 1GE7A 1BSWA 5D2BA 5CXAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2RJP A;  3K7N A;  1QJI A;  1BM6 A;  2X3A A;  3EDI A;  1GE6 A;  4GWN A;  1MMQ A;  4G9L A;  4G0D A;  3P1V A;  2POJ A;  456C A;  2OY4 A;  3HBU P;  3TSK A;  1B3D A;  3KRY A;  1CXV A;  1Y93 A;  1HV5 A;  2AIG P;  1CGE A;  1SRP A;  3B8Z A;  1I73 A;  2HU6 A;  1G05 A;  1XUC A;  4GR3 A;  3F18 A;  1RM8 A;  1FM1 A;  2Z2D A;  3LIR A;  1K7Q A;  2WO8 A;  3KEK A;  4J4M A;  1ROS A;  2WO9 A;  4PKS A;  4XM8 A;  1GO7 P;  3LIK A;  1O0T A;  4HX3 A;  1Y8J A;  4R3V A;  1PWQ A;  4GQL A;  4XM6 A;  1JAN A;  1G9K A;  1ZXV A;  4AUO A;  1ATL A;  1OS2 A;  1EUB A;  1KAP P;  1OM6 A;  2KRJ A;  4JIJ A;  5I4O A;  4DV8 A;  4AIG A;  2DW2 A;  1EB6 A;  4FVL A;  1BKC A;  1K7I A;  2J83 A;  3LJT A;  3L0V A;  1KUH A;  1BUV M;  2D1O A;  3Q2H A;  1PWP A;  1ZP5 A;  1K7G A;  3I7I A;  3MA2 A;  1UEA A;  2X3C A;  3OHL A;  4GWM A;  4IN9 A;  3ZUK A;  2OXW A;  1QJJ A;  3BA0 A;  1SMP A;  5D1S A;  1BQQ M;  4XM7 A;  3WV1 A;  1CIZ A;  2OY2 A;  2A8H A;  1ZTQ A;  1QIC A;  3HY9 A;  4XBH A;  2MZH A;  3EDG A;  5D1T A;  2RJQ A;  1JKY A;  1DMT A;  3EWJ A;  2E2D A;  2OXU A;  2FV9 A;  1Z3J A;  1GKD A;  2W13 A;  1YQY A;  1ZVX A;  4H82 A;  1C3I A;  3SHI A;  4H84 A;  1R54 A;  3UVC A;  1G12 A;  5BOT A;  3TVC A;  4FU4 A;  1USN A;  1GKC A;  1B8Y A;  1JIW P;  1R55 A;  4JQG A;  2SRT A;  1D8F A;  1I1I P;  1QUA A;  2DW1 A;  3F15 A;  2DW0 A;  3CKI A;  5CUH A;  1KUF A;  1JAQ A;  3LGP A;  2OXZ A;  3F19 A;  5I3M A;  1AST A;  2JT5 A;  4I03 A;  2N8R A;  1BQO A;  4IUW A;  3ZVS A;  3EDZ A;  4DPE A;  2JT6 A;  3DPF A;  966C A;  4IJO A;  2L0R A;  3P24 A;  2YIG A;  1OO9 A;  1QIA A;  3DWB A;  1JJ9 A;  5D3C A;  4FXY P;  830C A;  4DF9 A;  1HY7 A;  2OW2 A;  4PKQ A;  2OI0 A;  3F1A A;  2X3B A;  1MMR A;  1GXD A;  1JH1 A;  1SLN A;  3DPE A;  4Q1L A;  1OM7 A;  1XFV A;  2OVZ A;  2MLS A;  4PKT A;  1Q3A A;  4H30 A;  2OZR A;  1D7X A;  2OW0 A;  3EHY A;  4CTH A;  4QKZ A;  2ERQ A;  1XFX A;  1I76 A;  1IAG A;  2O36 A;  1ND1 A;  3LUN A;  1PWU A;  1A85 A;  1BUD A;  2XS4 A;  2W0D A;  1BZS A;  2JNP A;  1CGF A;  3Q2G A;  3RTS A;  3EHX A;  5JMY A;  1MNC A;  1HFC A;  1JIZ A;  2TCL A;  2O3E A;  2MZE A;  2WOA A;  2W15 A;  2E3X A;  4WF6 A;  1ZS0 A;  2DDF A;  1HTD A;  3OHO A;  1JK3 A;  1L6J A;  1CK7 A;  3WV3 A;  3DSL A;  1OMJ A;  1R1J A;  3F17 A;  1SU3 A;  3KWV C;  4JP4 A;  3LKA A;  2OVX A;  3AYK A;  1CGL A;  3GBO A;  1YP1 A;  1UTZ A;  3VI1 A;  1AF0 A;  3LMC A;  2D1N A;  1AKL A;  1MMB A;  1O0Q A;  3KME A;  2ERO A;  4L63 A;  2W14 A;  3AIG A;  3I7G A;  3N2U A;  2AYK A;  3HDB A;  1KUI A;  1PWW A;  1ZXC A;  1XUD A;  3TT4 A;  1D8M A;  1JAP A;  2V4B A;  1XFU A;  1HFS A;  4FXQ A;  4ON1 A;  1FBL A;  3WV2 A;  4GR0 A;  4WZV A;  3DNG A;  1D5J A;  1Y0V A;  1RMZ A;  5I12 A;  1WNI A;  1GE5 A;  2JSD A;  3USN A;  5BPA A;  2QPJ A;  2J0T A;  2MZI A;  4WKI A;  4H76 A;  3LJG A;  1BIW A;  1BKC E;  1H71 P;  1A86 A;  1XFW A;  5B5P A;  1C8T A;  2I47 A;  1CQR A;  2CKI A;  3ZXH A;  3LUM A;  4PKU A;  4AYK A;  3RTT A;  4H1Q A;  4JPA A;  1HOV A;  1SAT A;  4ZR5 A;  1QIB A;  5B5O A;  2K2G A;  4A3W A;  3HYG A;  1CAQ A;  1XFZ A;  2Y6C A;  3HDA P;  2CLT A;  3K7L A;  4PKW A;  1G49 A;  2ERP A;  2JIH A;  5LAB A;  1S4B P;  4ILW D;  3TS4 A;  1BKC I;  4GF1 A;  4GR8 A;  4PKV A;  3NX7 A;  4L6T A;  4PKR A;  4WKE A;  3LK8 A;  3LIL A;  1OS9 A;  1KBC A;  3O64 A;  1PWV A;  3HY7 A;  3G5C A;  5I43 A;  1MMP A;  1R1I A;  3VTG A;  3LJZ A;  4H49 A;  3V96 B;  3LE9 A;  5D7W A;  3LQ0 A;  1XUR A;  2PJT A;  3N2V A;  3G42 A;  3F16 A;  4EFS A;  3DL1 A;  1YCM A;  4A7B A;  3LQB A;  1GO8 P;  3KEJ A;  2X7M A;  2K9C A;  1AYK A;  4DD8 A;  4WK7 A;  1G4K A;  4XCT A;  1UMT A;  1FLS A;  3AYU A;  1R1H A;  1UTT A;  5D1U A;  1YOU A;  3L0T A;  1IAB A;  1JAO A;  2MLR A;  3KMC A;  5L7F A;  3O2X A;  1C7K A;  2W12 A;  3B92 A;  1DTH A;  2USN A;  3LEA A;  1J7N A;  3HB2 P;  2DDY A;  5CZM A;  2XS3 A;  4GUY A;  4I35 A;  1IAE A;  3KHI A;  5I0L A;  1KUG A;  2YB9 A;  4H3X A;  1OM8 A;  1KUK A;  2Y6D A;  1XFY A;  1IAC A;  3EDH A;  5I2Z A;  5BOY A;  1UMS A;  4AXQ A;  1EAK A;  3KEC A;  4JA1 A;  5L79 A;  3B2Z A;  4H2E A;  2FV5 A;  2OW1 A;  3E8R A;  3U1R A;  3ELM A;  3HBV P;  2OW9 A;  4L19 A;  1IAD A;  1IAA A;  1SLM A;  5H8X A;  4HMA A;  1GE7 A;  1BSW A;  5D2B A;  5CXA A; 
#chains in the Genus database with same CATH topology
 2RJP A;  3K7N A;  1QJI A;  1BM6 A;  2X3A A;  3EDI A;  1GE6 A;  4GWN A;  1MMQ A;  4G9L A;  4G0D A;  3P1V A;  2POJ A;  456C A;  2OY4 A;  3HBU P;  3TSK A;  1B3D A;  3KRY A;  1CXV A;  1Y93 A;  1HV5 A;  2AIG P;  1CGE A;  1SRP A;  3B8Z A;  1I73 A;  2HU6 A;  1G05 A;  1XUC A;  4GR3 A;  3F18 A;  1RM8 A;  1FM1 A;  2Z2D A;  3LIR A;  1K7Q A;  2WO8 A;  3KEK A;  4J4M A;  1ROS A;  2WO9 A;  4PKS A;  4XM8 A;  1GO7 P;  3LIK A;  1O0T A;  4HX3 A;  1Y8J A;  4R3V A;  1PWQ A;  4GQL A;  4XM6 A;  1JAN A;  1G9K A;  1ZXV A;  4AUO A;  1ATL A;  1OS2 A;  1TVI A;  1KAP P;  1OM6 A;  2KRJ A;  1EUB A;  4JIJ A;  5I4O A;  4DV8 A;  4AIG A;  2DW2 A;  1EB6 A;  4FVL A;  1BKC A;  1K7I A;  2J83 A;  3LJT A;  3L0V A;  3DTK A;  1KUH A;  1BUV M;  2D1O A;  3Q2H A;  1PWP A;  1ZP5 A;  1K7G A;  3I7I A;  3MA2 A;  4L7A A;  1UEA A;  2X3C A;  3OHL A;  4GWM A;  4IN9 A;  3ZUK A;  2OXW A;  1QJJ A;  3BA0 A;  1SMP A;  5D1S A;  1BQQ M;  4XM7 A;  3WV1 A;  1CIZ A;  2OY2 A;  2A8H A;  1ZTQ A;  1QIC A;  3HY9 A;  4XBH A;  2MZH A;  3EDG A;  5D1T A;  2RJQ A;  3DTI A;  1JKY A;  1DMT A;  3EWJ A;  2E2D A;  2OXU A;  2FV9 A;  1Z3J A;  1GKD A;  2W13 A;  1YQY A;  1ZVX A;  4H82 A;  1C3I A;  3SHI A;  4H84 A;  1R54 A;  3UVC A;  1G12 A;  5BOT A;  3TVC A;  4FU4 A;  1USN A;  1GKC A;  1B8Y A;  1JIW P;  1R55 A;  4JQG A;  2SRT A;  1D8F A;  1I1I P;  1QUA A;  2DW1 A;  3F15 A;  2DW0 A;  3CKI A;  5CUH A;  1KUF A;  1JAQ A;  3LGP A;  2OXZ A;  3F19 A;  5I3M A;  1AST A;  2JT5 A;  4I03 A;  2N8R A;  1BQO A;  4IUW A;  3ZVS A;  3EDZ A;  4DPE A;  2JT6 A;  3DPF A;  966C A;  4IJO A;  2L0R A;  3P24 A;  2YIG A;  1OO9 A;  1QIA A;  3DWB A;  1JJ9 A;  5D3C A;  4FXY P;  830C A;  4DF9 A;  1HY7 A;  2OW2 A;  4PKQ A;  2OI0 A;  3F1A A;  2X3B A;  1MMR A;  1GXD A;  1JH1 A;  1SLN A;  3DPE A;  4Q1L A;  1OM7 A;  1XFV A;  2OVZ A;  2MLS A;  4PKT A;  1Q3A A;  4H30 A;  2OZR A;  1D7X A;  2OW0 A;  3EHY A;  4CTH A;  4QKZ A;  2ERQ A;  1XFX A;  1I76 A;  1IAG A;  2O36 A;  1ND1 A;  3LUN A;  1PWU A;  1A85 A;  1BUD A;  2XS4 A;  2W0D A;  1BZS A;  2JNP A;  1CGF A;  3Q2G A;  3RTS A;  3EHX A;  5JMY A;  1MNC A;  1HFC A;  1JIZ A;  2TCL A;  2O3E A;  2MZE A;  2WOA A;  2W15 A;  2E3X A;  4WF6 A;  1ZS0 A;  2DDF A;  1HTD A;  3OHO A;  1JK3 A;  1L6J A;  1CK7 A;  3WV3 A;  3DSL A;  1OMJ A;  1R1J A;  3F17 A;  1SU3 A;  3KWV C;  4JP4 A;  3LKA A;  2OVX A;  3AYK A;  1CGL A;  3GBO A;  1YP1 A;  1UTZ A;  3VI1 A;  1AF0 A;  1XM5 A;  3LMC A;  2D1N A;  1AKL A;  1MMB A;  1O0Q A;  3KME A;  2ERO A;  4L63 A;  2W14 A;  3AIG A;  3I7G A;  3N2U A;  2AYK A;  3HDB A;  1KUI A;  1PWW A;  1ZXC A;  1XUD A;  3TT4 A;  1D8M A;  1JAP A;  2V4B A;  1XFU A;  1HFS A;  4FXQ A;  4ON1 A;  1FBL A;  3WV2 A;  4GR0 A;  4WZV A;  3DNG A;  1D5J A;  1Y0V A;  1RMZ A;  5I12 A;  1WNI A;  1GE5 A;  2JSD A;  3USN A;  5BPA A;  2QPJ A;  2J0T A;  2MZI A;  4WKI A;  4H76 A;  3LJG A;  1BIW A;  1BKC E;  1H71 P;  1A86 A;  1XFW A;  5B5P A;  1C8T A;  2I47 A;  1CQR A;  2CKI A;  3ZXH A;  2YUF A;  3LUM A;  4PKU A;  4AYK A;  3RTT A;  4H1Q A;  4JPA A;  1HOV A;  1SAT A;  4ZR5 A;  1QIB A;  1OZ9 A;  5B5O A;  2K2G A;  4A3W A;  3HYG A;  1CAQ A;  1XFZ A;  2Y6C A;  3HDA P;  1XAX A;  2CLT A;  3K7L A;  4PKW A;  1G49 A;  2ERP A;  2JIH A;  5LAB A;  1S4B P;  4ILW D;  3TS4 A;  1BKC I;  4GF1 A;  4GR8 A;  4PKV A;  3NX7 A;  4L6T A;  4PKR A;  4WKE A;  3LK8 A;  3LIL A;  1OS9 A;  1KBC A;  3O64 A;  1PWV A;  3HY7 A;  3G5C A;  5I43 A;  1MMP A;  1R1I A;  3VTG A;  3LJZ A;  4H49 A;  3V96 B;  3LE9 A;  5D7W A;  3LQ0 A;  1XUR A;  2PJT A;  3N2V A;  3G42 A;  3F16 A;  4EFS A;  3DL1 A;  1YCM A;  4A7B A;  3LQB A;  1GO8 P;  3KEJ A;  2X7M A;  2K9C A;  1AYK A;  4DD8 A;  4WK7 A;  1G4K A;  4XCT A;  1UMT A;  1FLS A;  3AYU A;  1R1H A;  1UTT A;  5D1U A;  1YOU A;  3L0T A;  1IAB A;  1JAO A;  2MLR A;  3KMC A;  5L7F A;  3O2X A;  1C7K A;  2W12 A;  3B92 A;  1DTH A;  2USN A;  3LEA A;  1J7N A;  3HB2 P;  2DDY A;  5CZM A;  2XS3 A;  4GUY A;  4I35 A;  1IAE A;  3KHI A;  5I0L A;  3DTE A;  1KUG A;  2YB9 A;  4H3X A;  1OM8 A;  1KUK A;  2Y6D A;  1XFY A;  1IAC A;  3EDH A;  5I2Z A;  5BOY A;  1UMS A;  4AXQ A;  1EAK A;  3KEC A;  4JA1 A;  5L79 A;  3B2Z A;  4H2E A;  2FV5 A;  2OW1 A;  3E8R A;  3U1R A;  3ELM A;  3HBV P;  2OW9 A;  4L19 A;  1IAD A;  1IAA A;  1SLM A;  5H8X A;  4HMA A;  1GE7 A;  1BSW A;  5D2B A;  5CXA A; 
#chains in the Genus database with same CATH homology
 2RJP A;  3K7N A;  1QJI A;  1BM6 A;  2X3A A;  3EDI A;  1GE6 A;  4GWN A;  1MMQ A;  4G9L A;  4G0D A;  3P1V A;  2POJ A;  456C A;  2OY4 A;  3HBU P;  3TSK A;  1B3D A;  3KRY A;  1CXV A;  1Y93 A;  1HV5 A;  2AIG P;  1CGE A;  1SRP A;  3B8Z A;  1I73 A;  2HU6 A;  1G05 A;  1XUC A;  4GR3 A;  3F18 A;  1RM8 A;  1FM1 A;  2Z2D A;  3LIR A;  1K7Q A;  2WO8 A;  3KEK A;  4J4M A;  1ROS A;  2WO9 A;  4PKS A;  4XM8 A;  1GO7 P;  3LIK A;  1O0T A;  4HX3 A;  1Y8J A;  4R3V A;  1PWQ A;  4GQL A;  4XM6 A;  1JAN A;  1G9K A;  1ZXV A;  4AUO A;  1ATL A;  1OS2 A;  1EUB A;  1KAP P;  1OM6 A;  2KRJ A;  4JIJ A;  5I4O A;  4DV8 A;  4AIG A;  2DW2 A;  1EB6 A;  4FVL A;  1BKC A;  1K7I A;  2J83 A;  3LJT A;  3L0V A;  3DTK A;  1KUH A;  1BUV M;  2D1O A;  3Q2H A;  1PWP A;  1ZP5 A;  1K7G A;  3I7I A;  3MA2 A;  4L7A A;  1UEA A;  2X3C A;  3OHL A;  4GWM A;  4IN9 A;  3ZUK A;  2OXW A;  1QJJ A;  3BA0 A;  1SMP A;  5D1S A;  1BQQ M;  4XM7 A;  3WV1 A;  1CIZ A;  2OY2 A;  2A8H A;  1ZTQ A;  1QIC A;  3HY9 A;  4XBH A;  2MZH A;  3EDG A;  5D1T A;  2RJQ A;  3DTI A;  1JKY A;  1DMT A;  3EWJ A;  2E2D A;  2OXU A;  2FV9 A;  1Z3J A;  1GKD A;  2W13 A;  1YQY A;  1ZVX A;  4H82 A;  1C3I A;  3SHI A;  4H84 A;  1R54 A;  3UVC A;  1G12 A;  5BOT A;  3TVC A;  4FU4 A;  1USN A;  1GKC A;  1B8Y A;  1JIW P;  1R55 A;  4JQG A;  2SRT A;  1D8F A;  1I1I P;  1QUA A;  2DW1 A;  3F15 A;  2DW0 A;  3CKI A;  5CUH A;  1KUF A;  1JAQ A;  3LGP A;  2OXZ A;  3F19 A;  5I3M A;  1AST A;  2JT5 A;  4I03 A;  2N8R A;  1BQO A;  4IUW A;  3ZVS A;  3EDZ A;  4DPE A;  2JT6 A;  3DPF A;  966C A;  4IJO A;  2L0R A;  3P24 A;  2YIG A;  1OO9 A;  1QIA A;  3DWB A;  1JJ9 A;  5D3C A;  4FXY P;  830C A;  4DF9 A;  1HY7 A;  2OW2 A;  4PKQ A;  2OI0 A;  3F1A A;  2X3B A;  1MMR A;  1GXD A;  1JH1 A;  1SLN A;  3DPE A;  4Q1L A;  1OM7 A;  1XFV A;  2OVZ A;  2MLS A;  4PKT A;  1Q3A A;  4H30 A;  2OZR A;  1D7X A;  2OW0 A;  3EHY A;  4CTH A;  4QKZ A;  2ERQ A;  1XFX A;  1I76 A;  1IAG A;  2O36 A;  1ND1 A;  3LUN A;  1PWU A;  1A85 A;  1BUD A;  2XS4 A;  2W0D A;  1BZS A;  2JNP A;  1CGF A;  3Q2G A;  3RTS A;  3EHX A;  5JMY A;  1MNC A;  1HFC A;  1JIZ A;  2TCL A;  2O3E A;  2MZE A;  2WOA A;  2W15 A;  2E3X A;  4WF6 A;  1ZS0 A;  2DDF A;  1HTD A;  3OHO A;  1JK3 A;  1L6J A;  1CK7 A;  3WV3 A;  3DSL A;  1OMJ A;  1R1J A;  3F17 A;  1SU3 A;  3KWV C;  4JP4 A;  3LKA A;  2OVX A;  3AYK A;  1CGL A;  3GBO A;  1YP1 A;  1UTZ A;  3VI1 A;  1AF0 A;  3LMC A;  2D1N A;  1AKL A;  1MMB A;  1O0Q A;  3KME A;  2ERO A;  4L63 A;  2W14 A;  3AIG A;  3I7G A;  3N2U A;  2AYK A;  3HDB A;  1KUI A;  1PWW A;  1ZXC A;  1XUD A;  3TT4 A;  1D8M A;  1JAP A;  2V4B A;  1XFU A;  1HFS A;  4FXQ A;  4ON1 A;  1FBL A;  3WV2 A;  4GR0 A;  4WZV A;  3DNG A;  1D5J A;  1Y0V A;  1RMZ A;  5I12 A;  1WNI A;  1GE5 A;  2JSD A;  3USN A;  5BPA A;  2QPJ A;  2J0T A;  2MZI A;  4WKI A;  4H76 A;  3LJG A;  1BIW A;  1BKC E;  1H71 P;  1A86 A;  1XFW A;  5B5P A;  1C8T A;  2I47 A;  1CQR A;  2CKI A;  3ZXH A;  2YUF A;  3LUM A;  4PKU A;  4AYK A;  3RTT A;  4H1Q A;  4JPA A;  1HOV A;  1SAT A;  4ZR5 A;  1QIB A;  5B5O A;  2K2G A;  4A3W A;  3HYG A;  1CAQ A;  1XFZ A;  2Y6C A;  3HDA P;  2CLT A;  3K7L A;  4PKW A;  1G49 A;  2ERP A;  2JIH A;  5LAB A;  1S4B P;  4ILW D;  3TS4 A;  1BKC I;  4GF1 A;  4GR8 A;  4PKV A;  3NX7 A;  4L6T A;  4PKR A;  4WKE A;  3LK8 A;  3LIL A;  1OS9 A;  1KBC A;  3O64 A;  1PWV A;  3HY7 A;  3G5C A;  5I43 A;  1MMP A;  1R1I A;  3VTG A;  3LJZ A;  4H49 A;  3V96 B;  3LE9 A;  5D7W A;  3LQ0 A;  1XUR A;  2PJT A;  3N2V A;  3G42 A;  3F16 A;  4EFS A;  3DL1 A;  1YCM A;  4A7B A;  3LQB A;  1GO8 P;  3KEJ A;  2X7M A;  2K9C A;  1AYK A;  4DD8 A;  4WK7 A;  1G4K A;  4XCT A;  1UMT A;  1FLS A;  3AYU A;  1R1H A;  1UTT A;  5D1U A;  1YOU A;  3L0T A;  1IAB A;  1JAO A;  2MLR A;  3KMC A;  5L7F A;  3O2X A;  1C7K A;  2W12 A;  3B92 A;  1DTH A;  2USN A;  3LEA A;  1J7N A;  3HB2 P;  2DDY A;  5CZM A;  2XS3 A;  4GUY A;  4I35 A;  1IAE A;  3KHI A;  5I0L A;  3DTE A;  1KUG A;  2YB9 A;  4H3X A;  1OM8 A;  1KUK A;  2Y6D A;  1XFY A;  1IAC A;  3EDH A;  5I2Z A;  5BOY A;  1UMS A;  4AXQ A;  1EAK A;  3KEC A;  4JA1 A;  5L79 A;  3B2Z A;  4H2E A;  2FV5 A;  2OW1 A;  3E8R A;  3U1R A;  3ELM A;  3HBV P;  2OW9 A;  4L19 A;  1IAD A;  1IAA A;  1SLM A;  5H8X A;  4HMA A;  1GE7 A;  1BSW A;  5D2B A;  5CXA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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