3F19A

Crystal structure of the catalytic domain of human mmp12 complexed with the inhibitor 4-fluoro-n-(2-nitroso-2-oxoethyl)benzenesulfonamide
Total Genus 44
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
44
sequence length
158
structure length
158
Chain Sequence
GPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Exploring the subtleties of drug-receptor interactions: the case of matrix metalloproteinases.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Macrophage metalloelastase
total genus 44
structure length 158
sequence length 158
ec nomenclature ec 3.4.24.65: Macrophage elastase.
pdb deposition date 2008-10-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 3f19A00
5D1SA 1AKLA 1FBLA 3AYUA 2N8RA 4I35A 3KHIA 1BKCA 3MA2A 1A85A 1BUVM 3EDHA 3N2UA 1BSWA 1SRPA 1CIZA 1I1IP 1IADA 1ZS0A 1OM7A 1R1HA 456CA 1PWWA 830CA 4XCTA 4GR8A 4CTHA 5I4OA 3KEJA 3VI1A 2I47A 2USNA 4DF9A 1ROSA 2CLTA 2E3XA 1I76A 1KUFA 2OXZA 3ZUKA 3N2VA 3HDBA 3HYGA 2WO8A 1BKCI 4DD8A 2RJQA 2TCLA 1Y93A 1RMZA 2DDFA 1IAEA 1EUBA 2K2GA 2JSDA 4H84A 4JQGA 1JAPA 4XM6A 3F15A 1B8YA 4IJOA 2OVXA 3LQBA 1KUKA 5JMYA 4XM7A 1GKDA 1CK7A 1C3IA 3OHOA 2DW1A 2AYKA 2X3CA 4H30A 3LUMA 4WZVA 1OO9A 1YQYA 1HFCA 4ILWD 3RTTA 3I7IA 4JP4A 4IUWA 1BUDA 1D8MA 1MMBA 1FM1A 1QJJA 3Q2HA 3G42A 1BZSA 3O2XA 1PWVA 2OI0A 4H49A 5D2BA 2O3EA 1OS2A 1OM6A 1PWUA 4ZR5A 1JJ9A 1QICA 3EWJA 1UMTA 4H3XA 1JANA 3TVCA 1D7XA 2W14A 1YP1A 3EHYA 1XFYA 1Y0VA 3LJZA 1B3DA 3KECA 1A86A 3P24A 4GWNA 4H76A 3L0TA 3K7LA 2OW2A 3DWBA 4XM8A 3B8ZA 2L0RA 3F18A 3LGPA 1Y8JA 3O64A 4GR3A 1G9KA 1YCMA 2Y6DA 3EHXA 3ELMA 1MNCA 1R1IA 3F1AA 4WK7A 3USNA 3SHIA 3LIKA 2X7MA 5L79A 2XS4A 2YIGA 1AYKA 3F17A 1QJIA 1L6JA 4A7BA 3F16A 3HY7A 3EDZA 4GUYA 1KUIA 3HBUP 2OZRA 3TT4A 1ZXVA 4H2EA 1ZTQA 1ZXCA 1HFSA 1AF0A 3U1RA 4FU4A 1ATLA 1CQRA 5I3MA 2OW9A 3OHLA 2E2DA 1GO8P 4AUOA 2SRTA 4AIGA 3NX7A 3B2ZA 1XFZA 3HY9A 5CUHA 1SMPA 5I12A 1O0TA 1GXDA 1XFUA 1BIWA 4L63A 1H71P 4JA1A 2W0DA 3B92A 3LMCA 1UTTA 2EROA 4J4MA 3LUNA 4GR0A 1C8TA 4DPEA 4PKRA 2FV5A 4XBHA 3L0VA 1XUCA 2YB9A 2OY4A 2J83A 2O36A 3LE9A 3EDGA 1KUGA 1XFWA 2JT6A 2OVZA 1DTHA 4ON1A 4FXYP 3LKAA 2ERPA 1DMTA 1SATA 5L7FA 5D1UA 1O0QA 1IABA 1G49A 3CKIA 1IAAA 3LK8A 1CXVA 1EAKA 2MLSA 1HTDA 3AIGA 2D1OA 1JAQA 4GWMA 1G12A 3HBVP 5D7WA 3WV3A 1D5JA 1R55A 2DDYA 1JAOA 4DV8A 4PKVA 2AIGP 2PJTA 1SLNA 2QPJA 3RTSA 2W12A 2CKIA 3LEAA 3G5CA 4GQLA 1RM8A 5I0LA 3ZVSA 2POJA 4GF1A 3BA0A 1Q3AA 1OM8A 1GE7A 3DPFA 1SLMA 4QKZA 1HV5A 1IACA 3TSKA 1SU3A 4WKEA 5D3CA 1IAGA 1UEAA 2K9CA 3HDAP 4EFSA 3VTGA 3KRYA 4G9LA 3I7GA 3V96B 2JIHA 4IN9A 3KWVC 3KMEA 1GE6A 1JK3A 1JIZA 3WV2A 1CAQA 4FVLA 4HMAA 1HOVA 2X3BA 3EDIA 1XUDA 2JT5A 1CGLA 1QIAA 1BKCE 1BQOA 1ASTA 4PKUA 1HY7A 1CGEA 1PWPA 2OW0A 2OXWA 5B5OA 2HU6A 3E8RA 1BQQM 4H1QA 4WKIA 5I43A 2ERQA 4JIJA 5D1TA 1MMPA 1R1JA 2OW1A 4A3WA 4Q1LA 5CXAA 3DNGA 3DPEA 2KRJA 3LILA 1QUAA 1KBCA 1ZVXA 2W13A 1I73A 4JPAA 4PKSA 2DW0A 2D1NA 2Z2DA 2MZHA 1GKCA 1CGFA 4PKQA 2DW2A 1G05A 3Q2GA 4AYKA 1J7NA 3DL1A 3F19A 1PWQA 2V4BA 1MMQA 1XFVA 5B5PA 1YOUA 1R54A 4L19A 1Z3JA 3P1VA 4WF6A 1OS9A 2OXUA 2WOAA 3LQ0A 1S4BP 1K7IA 1JIWP 2J0TA 5LABA 5BOYA 5CZMA 2FV9A 2X3AA 1JH1A 2Y6CA 1C7KA 1MMRA 3LIRA 2RJPA 1K7GA 1XFXA 4I03A 2JNPA 1GE5A 1JKYA 2MLRA 3GBOA 1FLSA 1K7QA 2MZEA 3ZXHA 1UMSA 1WNIA 4AXQA 3K7NA 3LJGA 1UTZA 1EB6A 3HB2P 4HX3A 1XURA 3AYKA 4R3VA 3TS4A 1G4KA 5I2ZA 5BPAA 4PKTA 2A8HA 1KUHA 3KEKA 5BOTA 4L6TA 1USNA 4G0DA 2W15A 1ND1A 3DSLA 1QIBA 2OY2A 4FXQA 966CA 1BM6A 3UVCA 1OMJA 2XS3A 2WO9A 4PKWA 1KAPP 1D8FA 2MZIA 1ZP5A 3KMCA 3WV1A 1GO7P 3LJTA 4H82A 5H8XA
chains in the Genus database with same CATH superfamily
5D1SA 1AKLA 1FBLA 3AYUA 1OZ9A 2N8RA 4I35A 3KHIA 1BKCA 3MA2A 1A85A 1BUVM 3EDHA 3N2UA 1BSWA 1SRPA 1CIZA 1I1IP 1IADA 1ZS0A 2YUFA 1OM7A 1R1HA 456CA 1PWWA 830CA 4XCTA 4GR8A 4CTHA 5I4OA 3KEJA 3VI1A 2I47A 2USNA 4DF9A 1ROSA 2CLTA 2E3XA 1I76A 1KUFA 2OXZA 3ZUKA 3N2VA 3HDBA 3HYGA 2WO8A 1BKCI 4DD8A 2RJQA 2TCLA 1Y93A 1RMZA 1XM5A 2DDFA 1IAEA 1EUBA 2K2GA 2JSDA 4H84A 4JQGA 1JAPA 4XM6A 3F15A 1B8YA 4IJOA 2OVXA 3LQBA 1KUKA 5JMYA 4XM7A 1GKDA 1CK7A 1C3IA 3OHOA 2DW1A 2AYKA 2X3CA 4H30A 3LUMA 4WZVA 1OO9A 1YQYA 1HFCA 4ILWD 3RTTA 3I7IA 4JP4A 4IUWA 1BUDA 1D8MA 1MMBA 1FM1A 1QJJA 3Q2HA 3G42A 1BZSA 3O2XA 1PWVA 2OI0A 4H49A 5D2BA 2O3EA 1OS2A 1OM6A 1PWUA 4ZR5A 1JJ9A 1QICA 3EWJA 1UMTA 4H3XA 1JANA 3TVCA 1D7XA 2W14A 1YP1A 3EHYA 1XFYA 1Y0VA 3LJZA 1B3DA 3KECA 1A86A 3P24A 4GWNA 4H76A 3L0TA 3K7LA 2OW2A 3DWBA 4XM8A 3B8ZA 2L0RA 3F18A 3LGPA 1Y8JA 3O64A 4GR3A 1G9KA 1YCMA 2Y6DA 3EHXA 3ELMA 1MNCA 1R1IA 3F1AA 4WK7A 3USNA 3SHIA 3LIKA 2X7MA 5L79A 2XS4A 2YIGA 1AYKA 3F17A 1QJIA 1L6JA 4A7BA 3F16A 3HY7A 3EDZA 4GUYA 1KUIA 3HBUP 2OZRA 3TT4A 3DTKA 1ZXVA 4H2EA 1ZTQA 1ZXCA 1HFSA 1AF0A 3U1RA 4L7AA 4FU4A 1TVIA 1ATLA 1CQRA 5I3MA 2OW9A 3OHLA 2E2DA 1GO8P 1XAXA 4AUOA 2SRTA 4AIGA 3NX7A 3B2ZA 1XFZA 3HY9A 5CUHA 1SMPA 5I12A 1O0TA 1GXDA 1XFUA 1BIWA 4L63A 1H71P 4JA1A 2W0DA 3B92A 3LMCA 1UTTA 2EROA 4J4MA 3LUNA 4GR0A 1C8TA 4DPEA 4PKRA 2FV5A 4XBHA 3L0VA 1XUCA 2YB9A 2OY4A 3DTEA 2J83A 2O36A 3LE9A 3EDGA 1KUGA 1XFWA 2JT6A 2OVZA 1DTHA 4ON1A 4FXYP 3LKAA 2ERPA 1DMTA 1SATA 5L7FA 5D1UA 1O0QA 1IABA 1G49A 3CKIA 1IAAA 3LK8A 1CXVA 1EAKA 2MLSA 1HTDA 3AIGA 2D1OA 1JAQA 4GWMA 1G12A 3HBVP 5D7WA 3WV3A 1D5JA 1R55A 2DDYA 1JAOA 4DV8A 4PKVA 2AIGP 2PJTA 1SLNA 2QPJA 3RTSA 2W12A 2CKIA 3LEAA 3G5CA 4GQLA 1RM8A 5I0LA 3ZVSA 2POJA 4GF1A 3BA0A 1Q3AA 1OM8A 1GE7A 3DPFA 1SLMA 4QKZA 1HV5A 1IACA 3TSKA 1SU3A 4WKEA 5D3CA 1IAGA 1UEAA 2K9CA 3HDAP 4EFSA 3VTGA 3KRYA 4G9LA 3I7GA 3V96B 2JIHA 4IN9A 3KWVC 3KMEA 1GE6A 1JK3A 1JIZA 3WV2A 1CAQA 4FVLA 4HMAA 1HOVA 2X3BA 3EDIA 1XUDA 2JT5A 1CGLA 1QIAA 1BKCE 1BQOA 1ASTA 4PKUA 1HY7A 1CGEA 1PWPA 3DTIA 2OW0A 2OXWA 5B5OA 2HU6A 3E8RA 1BQQM 4H1QA 4WKIA 5I43A 2ERQA 4JIJA 5D1TA 1MMPA 1R1JA 2OW1A 4A3WA 4Q1LA 5CXAA 3DNGA 3DPEA 2KRJA 3LILA 1QUAA 1KBCA 1ZVXA 2W13A 1I73A 4JPAA 4PKSA 2DW0A 2D1NA 2Z2DA 2MZHA 1GKCA 1CGFA 4PKQA 2DW2A 1G05A 3Q2GA 4AYKA 1J7NA 3DL1A 3F19A 1PWQA 2V4BA 1MMQA 1XFVA 5B5PA 1YOUA 1R54A 4L19A 1Z3JA 3P1VA 4WF6A 1OS9A 2OXUA 2WOAA 3LQ0A 1S4BP 1K7IA 1JIWP 2J0TA 5LABA 5BOYA 5CZMA 2X3AA 2FV9A 1JH1A 2Y6CA 1C7KA 1MMRA 3LIRA 2RJPA 1K7GA 1XFXA 4I03A 2JNPA 1GE5A 1JKYA 2MLRA 3GBOA 1FLSA 1K7QA 2MZEA 3ZXHA 1UMSA 1WNIA 4AXQA 3K7NA 3LJGA 1UTZA 1EB6A 3HB2P 4HX3A 1XURA 3AYKA 4R3VA 3TS4A 1G4KA 5I2ZA 5BPAA 4PKTA 2A8HA 1KUHA 3KEKA 5BOTA 4L6TA 1USNA 4G0DA 2W15A 1ND1A 3DSLA 1QIBA 2OY2A 4FXQA 966CA 1BM6A 3UVCA 1OMJA 2XS3A 2WO9A 4PKWA 1KAPP 1D8FA 2MZIA 1ZP5A 3KMCA 3WV1A 1GO7P 3LJTA 4H82A 5H8XA
chains in the Genus database with same CATH topology
5D1SA 1AKLA 1FBLA 3AYUA 2N8RA 4I35A 3KHIA 1BKCA 3MA2A 1A85A 1BUVM 3EDHA 3N2UA 1BSWA 1SRPA 1CIZA 1I1IP 1IADA 1ZS0A 2YUFA 1OM7A 1R1HA 456CA 1PWWA 830CA 4XCTA 4GR8A 4CTHA 5I4OA 3KEJA 3VI1A 2I47A 2USNA 4DF9A 1ROSA 2CLTA 2E3XA 1I76A 1KUFA 2OXZA 3ZUKA 3N2VA 3HDBA 3HYGA 2WO8A 1BKCI 4DD8A 2RJQA 2TCLA 1Y93A 1RMZA 2DDFA 1IAEA 1EUBA 2K2GA 2JSDA 4H84A 4JQGA 1JAPA 4XM6A 3F15A 1B8YA 4IJOA 2OVXA 3LQBA 1KUKA 5JMYA 4XM7A 1GKDA 1CK7A 1C3IA 3OHOA 2DW1A 2AYKA 2X3CA 4H30A 3LUMA 4WZVA 1OO9A 1YQYA 1HFCA 4ILWD 3RTTA 3I7IA 4JP4A 4IUWA 1BUDA 1D8MA 1MMBA 1FM1A 1QJJA 3Q2HA 3G42A 1BZSA 3O2XA 1PWVA 2OI0A 4H49A 5D2BA 2O3EA 1OS2A 1OM6A 1PWUA 4ZR5A 1JJ9A 1QICA 3EWJA 1UMTA 4H3XA 1JANA 3TVCA 1D7XA 2W14A 1YP1A 3EHYA 1XFYA 1Y0VA 3LJZA 1B3DA 3KECA 1A86A 3P24A 4GWNA 4H76A 3L0TA 3K7LA 2OW2A 3DWBA 4XM8A 3B8ZA 2L0RA 3F18A 3LGPA 1Y8JA 3O64A 4GR3A 1G9KA 1YCMA 2Y6DA 3EHXA 3ELMA 1MNCA 1R1IA 3F1AA 4WK7A 3USNA 3SHIA 3LIKA 2X7MA 5L79A 2XS4A 2YIGA 1AYKA 3F17A 1QJIA 1L6JA 4A7BA 3F16A 3HY7A 3EDZA 4GUYA 1KUIA 3HBUP 2OZRA 3TT4A 3DTKA 1ZXVA 4H2EA 1ZTQA 1ZXCA 1HFSA 1AF0A 3U1RA 4L7AA 4FU4A 1ATLA 1CQRA 5I3MA 2OW9A 3OHLA 2E2DA 1GO8P 4AUOA 2SRTA 4AIGA 3NX7A 3B2ZA 1XFZA 3HY9A 5CUHA 1SMPA 5I12A 1O0TA 1GXDA 1XFUA 1BIWA 4L63A 1H71P 4JA1A 2W0DA 3B92A 3LMCA 1UTTA 2EROA 4J4MA 3LUNA 4GR0A 1C8TA 4DPEA 4PKRA 2FV5A 4XBHA 3L0VA 1XUCA 2YB9A 2OY4A 3DTEA 2J83A 2O36A 3LE9A 3EDGA 1KUGA 1XFWA 2JT6A 2OVZA 1DTHA 4ON1A 4FXYP 3LKAA 2ERPA 1DMTA 1SATA 5L7FA 5D1UA 1O0QA 1IABA 1G49A 3CKIA 1IAAA 3LK8A 1CXVA 1EAKA 2MLSA 1HTDA 3AIGA 2D1OA 1JAQA 4GWMA 1G12A 3HBVP 5D7WA 3WV3A 1D5JA 1R55A 2DDYA 1JAOA 4DV8A 4PKVA 2AIGP 2PJTA 1SLNA 2QPJA 3RTSA 2W12A 2CKIA 3LEAA 3G5CA 4GQLA 1RM8A 5I0LA 3ZVSA 2POJA 4GF1A 3BA0A 1Q3AA 1OM8A 1GE7A 3DPFA 1SLMA 4QKZA 1HV5A 1IACA 3TSKA 1SU3A 4WKEA 5D3CA 1IAGA 1UEAA 2K9CA 3HDAP 4EFSA 3VTGA 3KRYA 4G9LA 3I7GA 3V96B 2JIHA 4IN9A 3KWVC 3KMEA 1GE6A 1JK3A 1JIZA 3WV2A 1CAQA 4FVLA 4HMAA 1HOVA 2X3BA 3EDIA 1XUDA 2JT5A 1CGLA 1QIAA 1BKCE 1BQOA 1ASTA 4PKUA 1HY7A 1CGEA 1PWPA 3DTIA 2OW0A 2OXWA 5B5OA 2HU6A 3E8RA 1BQQM 4H1QA 4WKIA 5I43A 2ERQA 4JIJA 5D1TA 1MMPA 1R1JA 2OW1A 4A3WA 4Q1LA 5CXAA 3DNGA 3DPEA 2KRJA 3LILA 1QUAA 1KBCA 1ZVXA 2W13A 1I73A 4JPAA 4PKSA 2DW0A 2D1NA 2Z2DA 2MZHA 1GKCA 1CGFA 4PKQA 2DW2A 1G05A 3Q2GA 4AYKA 1J7NA 3DL1A 3F19A 1PWQA 2V4BA 1MMQA 1XFVA 5B5PA 1YOUA 1R54A 4L19A 1Z3JA 3P1VA 4WF6A 1OS9A 2OXUA 2WOAA 3LQ0A 1S4BP 1K7IA 1JIWP 2J0TA 5LABA 5BOYA 5CZMA 2FV9A 2X3AA 1JH1A 2Y6CA 1C7KA 1MMRA 3LIRA 2RJPA 1K7GA 1XFXA 4I03A 2JNPA 1GE5A 1JKYA 2MLRA 3GBOA 1FLSA 1K7QA 2MZEA 3ZXHA 1UMSA 1WNIA 4AXQA 3K7NA 3LJGA 1UTZA 1EB6A 3HB2P 4HX3A 1XURA 3AYKA 4R3VA 3TS4A 1G4KA 5I2ZA 5BPAA 4PKTA 2A8HA 1KUHA 3KEKA 5BOTA 4L6TA 1USNA 4G0DA 2W15A 1ND1A 3DSLA 1QIBA 2OY2A 4FXQA 966CA 1BM6A 3UVCA 1OMJA 2XS3A 2WO9A 4PKWA 1KAPP 1D8FA 2MZIA 1ZP5A 3KMCA 3WV1A 1GO7P 3LJTA 4H82A 5H8XA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5D1S A;  1AKL A;  1FBL A;  3AYU A;  2N8R A;  4I35 A;  3KHI A;  1BKC A;  3MA2 A;  1A85 A;  1BUV M;  3EDH A;  3N2U A;  1BSW A;  1SRP A;  1CIZ A;  1I1I P;  1IAD A;  1ZS0 A;  1OM7 A;  1R1H A;  456C A;  1PWW A;  830C A;  4XCT A;  4GR8 A;  4CTH A;  5I4O A;  3KEJ A;  3VI1 A;  2I47 A;  2USN A;  4DF9 A;  1ROS A;  2CLT A;  2E3X A;  1I76 A;  1KUF A;  2OXZ A;  3ZUK A;  3N2V A;  3HDB A;  3HYG A;  2WO8 A;  1BKC I;  4DD8 A;  2RJQ A;  2TCL A;  1Y93 A;  1RMZ A;  2DDF A;  1IAE A;  1EUB A;  2K2G A;  2JSD A;  4H84 A;  4JQG A;  1JAP A;  4XM6 A;  3F15 A;  1B8Y A;  4IJO A;  2OVX A;  3LQB A;  1KUK A;  5JMY A;  4XM7 A;  1GKD A;  1CK7 A;  1C3I A;  3OHO A;  2DW1 A;  2AYK A;  2X3C A;  4H30 A;  3LUM A;  4WZV A;  1OO9 A;  1YQY A;  1HFC A;  4ILW D;  3RTT A;  3I7I A;  4JP4 A;  4IUW A;  1BUD A;  1D8M A;  1MMB A;  1FM1 A;  1QJJ A;  3Q2H A;  3G42 A;  1BZS A;  3O2X A;  1PWV A;  2OI0 A;  4H49 A;  5D2B A;  2O3E A;  1OS2 A;  1OM6 A;  1PWU A;  4ZR5 A;  1JJ9 A;  1QIC A;  3EWJ A;  1UMT A;  4H3X A;  1JAN A;  3TVC A;  1D7X A;  2W14 A;  1YP1 A;  3EHY A;  1XFY A;  1Y0V A;  3LJZ A;  1B3D A;  3KEC A;  1A86 A;  3P24 A;  4GWN A;  4H76 A;  3L0T A;  3K7L A;  2OW2 A;  3DWB A;  4XM8 A;  3B8Z A;  2L0R A;  3F18 A;  3LGP A;  1Y8J A;  3O64 A;  4GR3 A;  1G9K A;  1YCM A;  2Y6D A;  3EHX A;  3ELM A;  1MNC A;  1R1I A;  3F1A A;  4WK7 A;  3USN A;  3SHI A;  3LIK A;  2X7M A;  5L79 A;  2XS4 A;  2YIG A;  1AYK A;  3F17 A;  1QJI A;  1L6J A;  4A7B A;  3F16 A;  3HY7 A;  3EDZ A;  4GUY A;  1KUI A;  3HBU P;  2OZR A;  3TT4 A;  1ZXV A;  4H2E A;  1ZTQ A;  1ZXC A;  1HFS A;  1AF0 A;  3U1R A;  4FU4 A;  1ATL A;  1CQR A;  5I3M A;  2OW9 A;  3OHL A;  2E2D A;  1GO8 P;  4AUO A;  2SRT A;  4AIG A;  3NX7 A;  3B2Z A;  1XFZ A;  3HY9 A;  5CUH A;  1SMP A;  5I12 A;  1O0T A;  1GXD A;  1XFU A;  1BIW A;  4L63 A;  1H71 P;  4JA1 A;  2W0D A;  3B92 A;  3LMC A;  1UTT A;  2ERO A;  4J4M A;  3LUN A;  4GR0 A;  1C8T A;  4DPE A;  4PKR A;  2FV5 A;  4XBH A;  3L0V A;  1XUC A;  2YB9 A;  2OY4 A;  2J83 A;  2O36 A;  3LE9 A;  3EDG A;  1KUG A;  1XFW A;  2JT6 A;  2OVZ A;  1DTH A;  4ON1 A;  4FXY P;  3LKA A;  2ERP A;  1DMT A;  1SAT A;  5L7F A;  5D1U A;  1O0Q A;  1IAB A;  1G49 A;  3CKI A;  1IAA A;  3LK8 A;  1CXV A;  1EAK A;  2MLS A;  1HTD A;  3AIG A;  2D1O A;  1JAQ A;  4GWM A;  1G12 A;  3HBV P;  5D7W A;  3WV3 A;  1D5J A;  1R55 A;  2DDY A;  1JAO A;  4DV8 A;  4PKV A;  2AIG P;  2PJT A;  1SLN A;  2QPJ A;  3RTS A;  2W12 A;  2CKI A;  3LEA A;  3G5C A;  4GQL A;  1RM8 A;  5I0L A;  3ZVS A;  2POJ A;  4GF1 A;  3BA0 A;  1Q3A A;  1OM8 A;  1GE7 A;  3DPF A;  1SLM A;  4QKZ A;  1HV5 A;  1IAC A;  3TSK A;  1SU3 A;  4WKE A;  5D3C A;  1IAG A;  1UEA A;  2K9C A;  3HDA P;  4EFS A;  3VTG A;  3KRY A;  4G9L A;  3I7G A;  3V96 B;  2JIH A;  4IN9 A;  3KWV C;  3KME A;  1GE6 A;  1JK3 A;  1JIZ A;  3WV2 A;  1CAQ A;  4FVL A;  4HMA A;  1HOV A;  2X3B A;  3EDI A;  1XUD A;  2JT5 A;  1CGL A;  1QIA A;  1BKC E;  1BQO A;  1AST A;  4PKU A;  1HY7 A;  1CGE A;  1PWP A;  2OW0 A;  2OXW A;  5B5O A;  2HU6 A;  3E8R A;  1BQQ M;  4H1Q A;  4WKI A;  5I43 A;  2ERQ A;  4JIJ A;  5D1T A;  1MMP A;  1R1J A;  2OW1 A;  4A3W A;  4Q1L A;  5CXA A;  3DNG A;  3DPE A;  2KRJ A;  3LIL A;  1QUA A;  1KBC A;  1ZVX A;  2W13 A;  1I73 A;  4JPA A;  4PKS A;  2DW0 A;  2D1N A;  2Z2D A;  2MZH A;  1GKC A;  1CGF A;  4PKQ A;  2DW2 A;  1G05 A;  3Q2G A;  4AYK A;  1J7N A;  3DL1 A;  3F19 A;  1PWQ A;  2V4B A;  1MMQ A;  1XFV A;  5B5P A;  1YOU A;  1R54 A;  4L19 A;  1Z3J A;  3P1V A;  4WF6 A;  1OS9 A;  2OXU A;  2WOA A;  3LQ0 A;  1S4B P;  1K7I A;  1JIW P;  2J0T A;  5LAB A;  5BOY A;  5CZM A;  2FV9 A;  2X3A A;  1JH1 A;  2Y6C A;  1C7K A;  1MMR A;  3LIR A;  2RJP A;  1K7G A;  1XFX A;  4I03 A;  2JNP A;  1GE5 A;  1JKY A;  2MLR A;  3GBO A;  1FLS A;  1K7Q A;  2MZE A;  3ZXH A;  1UMS A;  1WNI A;  4AXQ A;  3K7N A;  3LJG A;  1UTZ A;  1EB6 A;  3HB2 P;  4HX3 A;  1XUR A;  3AYK A;  4R3V A;  3TS4 A;  1G4K A;  5I2Z A;  5BPA A;  4PKT A;  2A8H A;  1KUH A;  3KEK A;  5BOT A;  4L6T A;  1USN A;  4G0D A;  2W15 A;  1ND1 A;  3DSL A;  1QIB A;  2OY2 A;  4FXQ A;  966C A;  1BM6 A;  3UVC A;  1OMJ A;  2XS3 A;  2WO9 A;  4PKW A;  1KAP P;  1D8F A;  2MZI A;  1ZP5 A;  3KMC A;  3WV1 A;  1GO7 P;  3LJT A;  4H82 A;  5H8X A; 
#chains in the Genus database with same CATH topology
 5D1S A;  1AKL A;  1FBL A;  3AYU A;  1OZ9 A;  2N8R A;  4I35 A;  3KHI A;  1BKC A;  3MA2 A;  1A85 A;  1BUV M;  3EDH A;  3N2U A;  1BSW A;  1SRP A;  1CIZ A;  1I1I P;  1IAD A;  1ZS0 A;  2YUF A;  1OM7 A;  1R1H A;  456C A;  1PWW A;  830C A;  4XCT A;  4GR8 A;  4CTH A;  5I4O A;  3KEJ A;  3VI1 A;  2I47 A;  2USN A;  4DF9 A;  1ROS A;  2CLT A;  2E3X A;  1I76 A;  1KUF A;  2OXZ A;  3ZUK A;  3N2V A;  3HDB A;  3HYG A;  2WO8 A;  1BKC I;  4DD8 A;  2RJQ A;  2TCL A;  1Y93 A;  1RMZ A;  1XM5 A;  2DDF A;  1IAE A;  1EUB A;  2K2G A;  2JSD A;  4H84 A;  4JQG A;  1JAP A;  4XM6 A;  3F15 A;  1B8Y A;  4IJO A;  2OVX A;  3LQB A;  1KUK A;  5JMY A;  4XM7 A;  1GKD A;  1CK7 A;  1C3I A;  3OHO A;  2DW1 A;  2AYK A;  2X3C A;  4H30 A;  3LUM A;  4WZV A;  1OO9 A;  1YQY A;  1HFC A;  4ILW D;  3RTT A;  3I7I A;  4JP4 A;  4IUW A;  1BUD A;  1D8M A;  1MMB A;  1FM1 A;  1QJJ A;  3Q2H A;  3G42 A;  1BZS A;  3O2X A;  1PWV A;  2OI0 A;  4H49 A;  5D2B A;  2O3E A;  1OS2 A;  1OM6 A;  1PWU A;  4ZR5 A;  1JJ9 A;  1QIC A;  3EWJ A;  1UMT A;  4H3X A;  1JAN A;  3TVC A;  1D7X A;  2W14 A;  1YP1 A;  3EHY A;  1XFY A;  1Y0V A;  3LJZ A;  1B3D A;  3KEC A;  1A86 A;  3P24 A;  4GWN A;  4H76 A;  3L0T A;  3K7L A;  2OW2 A;  3DWB A;  4XM8 A;  3B8Z A;  2L0R A;  3F18 A;  3LGP A;  1Y8J A;  3O64 A;  4GR3 A;  1G9K A;  1YCM A;  2Y6D A;  3EHX A;  3ELM A;  1MNC A;  1R1I A;  3F1A A;  4WK7 A;  3USN A;  3SHI A;  3LIK A;  2X7M A;  5L79 A;  2XS4 A;  2YIG A;  1AYK A;  3F17 A;  1QJI A;  1L6J A;  4A7B A;  3F16 A;  3HY7 A;  3EDZ A;  4GUY A;  1KUI A;  3HBU P;  2OZR A;  3TT4 A;  3DTK A;  1ZXV A;  4H2E A;  1ZTQ A;  1ZXC A;  1HFS A;  1AF0 A;  3U1R A;  4L7A A;  4FU4 A;  1TVI A;  1ATL A;  1CQR A;  5I3M A;  2OW9 A;  3OHL A;  2E2D A;  1GO8 P;  1XAX A;  4AUO A;  2SRT A;  4AIG A;  3NX7 A;  3B2Z A;  1XFZ A;  3HY9 A;  5CUH A;  1SMP A;  5I12 A;  1O0T A;  1GXD A;  1XFU A;  1BIW A;  4L63 A;  1H71 P;  4JA1 A;  2W0D A;  3B92 A;  3LMC A;  1UTT A;  2ERO A;  4J4M A;  3LUN A;  4GR0 A;  1C8T A;  4DPE A;  4PKR A;  2FV5 A;  4XBH A;  3L0V A;  1XUC A;  2YB9 A;  2OY4 A;  3DTE A;  2J83 A;  2O36 A;  3LE9 A;  3EDG A;  1KUG A;  1XFW A;  2JT6 A;  2OVZ A;  1DTH A;  4ON1 A;  4FXY P;  3LKA A;  2ERP A;  1DMT A;  1SAT A;  5L7F A;  5D1U A;  1O0Q A;  1IAB A;  1G49 A;  3CKI A;  1IAA A;  3LK8 A;  1CXV A;  1EAK A;  2MLS A;  1HTD A;  3AIG A;  2D1O A;  1JAQ A;  4GWM A;  1G12 A;  3HBV P;  5D7W A;  3WV3 A;  1D5J A;  1R55 A;  2DDY A;  1JAO A;  4DV8 A;  4PKV A;  2AIG P;  2PJT A;  1SLN A;  2QPJ A;  3RTS A;  2W12 A;  2CKI A;  3LEA A;  3G5C A;  4GQL A;  1RM8 A;  5I0L A;  3ZVS A;  2POJ A;  4GF1 A;  3BA0 A;  1Q3A A;  1OM8 A;  1GE7 A;  3DPF A;  1SLM A;  4QKZ A;  1HV5 A;  1IAC A;  3TSK A;  1SU3 A;  4WKE A;  5D3C A;  1IAG A;  1UEA A;  2K9C A;  3HDA P;  4EFS A;  3VTG A;  3KRY A;  4G9L A;  3I7G A;  3V96 B;  2JIH A;  4IN9 A;  3KWV C;  3KME A;  1GE6 A;  1JK3 A;  1JIZ A;  3WV2 A;  1CAQ A;  4FVL A;  4HMA A;  1HOV A;  2X3B A;  3EDI A;  1XUD A;  2JT5 A;  1CGL A;  1QIA A;  1BKC E;  1BQO A;  1AST A;  4PKU A;  1HY7 A;  1CGE A;  1PWP A;  3DTI A;  2OW0 A;  2OXW A;  5B5O A;  2HU6 A;  3E8R A;  1BQQ M;  4H1Q A;  4WKI A;  5I43 A;  2ERQ A;  4JIJ A;  5D1T A;  1MMP A;  1R1J A;  2OW1 A;  4A3W A;  4Q1L A;  5CXA A;  3DNG A;  3DPE A;  2KRJ A;  3LIL A;  1QUA A;  1KBC A;  1ZVX A;  2W13 A;  1I73 A;  4JPA A;  4PKS A;  2DW0 A;  2D1N A;  2Z2D A;  2MZH A;  1GKC A;  1CGF A;  4PKQ A;  2DW2 A;  1G05 A;  3Q2G A;  4AYK A;  1J7N A;  3DL1 A;  3F19 A;  1PWQ A;  2V4B A;  1MMQ A;  1XFV A;  5B5P A;  1YOU A;  1R54 A;  4L19 A;  1Z3J A;  3P1V A;  4WF6 A;  1OS9 A;  2OXU A;  2WOA A;  3LQ0 A;  1S4B P;  1K7I A;  1JIW P;  2J0T A;  5LAB A;  5BOY A;  5CZM A;  2X3A A;  2FV9 A;  1JH1 A;  2Y6C A;  1C7K A;  1MMR A;  3LIR A;  2RJP A;  1K7G A;  1XFX A;  4I03 A;  2JNP A;  1GE5 A;  1JKY A;  2MLR A;  3GBO A;  1FLS A;  1K7Q A;  2MZE A;  3ZXH A;  1UMS A;  1WNI A;  4AXQ A;  3K7N A;  3LJG A;  1UTZ A;  1EB6 A;  3HB2 P;  4HX3 A;  1XUR A;  3AYK A;  4R3V A;  3TS4 A;  1G4K A;  5I2Z A;  5BPA A;  4PKT A;  2A8H A;  1KUH A;  3KEK A;  5BOT A;  4L6T A;  1USN A;  4G0D A;  2W15 A;  1ND1 A;  3DSL A;  1QIB A;  2OY2 A;  4FXQ A;  966C A;  1BM6 A;  3UVC A;  1OMJ A;  2XS3 A;  2WO9 A;  4PKW A;  1KAP P;  1D8F A;  2MZI A;  1ZP5 A;  3KMC A;  3WV1 A;  1GO7 P;  3LJT A;  4H82 A;  5H8X A; 
#chains in the Genus database with same CATH homology
 5D1S A;  1AKL A;  1FBL A;  3AYU A;  2N8R A;  4I35 A;  3KHI A;  1BKC A;  3MA2 A;  1A85 A;  1BUV M;  3EDH A;  3N2U A;  1BSW A;  1SRP A;  1CIZ A;  1I1I P;  1IAD A;  1ZS0 A;  2YUF A;  1OM7 A;  1R1H A;  456C A;  1PWW A;  830C A;  4XCT A;  4GR8 A;  4CTH A;  5I4O A;  3KEJ A;  3VI1 A;  2I47 A;  2USN A;  4DF9 A;  1ROS A;  2CLT A;  2E3X A;  1I76 A;  1KUF A;  2OXZ A;  3ZUK A;  3N2V A;  3HDB A;  3HYG A;  2WO8 A;  1BKC I;  4DD8 A;  2RJQ A;  2TCL A;  1Y93 A;  1RMZ A;  2DDF A;  1IAE A;  1EUB A;  2K2G A;  2JSD A;  4H84 A;  4JQG A;  1JAP A;  4XM6 A;  3F15 A;  1B8Y A;  4IJO A;  2OVX A;  3LQB A;  1KUK A;  5JMY A;  4XM7 A;  1GKD A;  1CK7 A;  1C3I A;  3OHO A;  2DW1 A;  2AYK A;  2X3C A;  4H30 A;  3LUM A;  4WZV A;  1OO9 A;  1YQY A;  1HFC A;  4ILW D;  3RTT A;  3I7I A;  4JP4 A;  4IUW A;  1BUD A;  1D8M A;  1MMB A;  1FM1 A;  1QJJ A;  3Q2H A;  3G42 A;  1BZS A;  3O2X A;  1PWV A;  2OI0 A;  4H49 A;  5D2B A;  2O3E A;  1OS2 A;  1OM6 A;  1PWU A;  4ZR5 A;  1JJ9 A;  1QIC A;  3EWJ A;  1UMT A;  4H3X A;  1JAN A;  3TVC A;  1D7X A;  2W14 A;  1YP1 A;  3EHY A;  1XFY A;  1Y0V A;  3LJZ A;  1B3D A;  3KEC A;  1A86 A;  3P24 A;  4GWN A;  4H76 A;  3L0T A;  3K7L A;  2OW2 A;  3DWB A;  4XM8 A;  3B8Z A;  2L0R A;  3F18 A;  3LGP A;  1Y8J A;  3O64 A;  4GR3 A;  1G9K A;  1YCM A;  2Y6D A;  3EHX A;  3ELM A;  1MNC A;  1R1I A;  3F1A A;  4WK7 A;  3USN A;  3SHI A;  3LIK A;  2X7M A;  5L79 A;  2XS4 A;  2YIG A;  1AYK A;  3F17 A;  1QJI A;  1L6J A;  4A7B A;  3F16 A;  3HY7 A;  3EDZ A;  4GUY A;  1KUI A;  3HBU P;  2OZR A;  3TT4 A;  3DTK A;  1ZXV A;  4H2E A;  1ZTQ A;  1ZXC A;  1HFS A;  1AF0 A;  3U1R A;  4L7A A;  4FU4 A;  1ATL A;  1CQR A;  5I3M A;  2OW9 A;  3OHL A;  2E2D A;  1GO8 P;  4AUO A;  2SRT A;  4AIG A;  3NX7 A;  3B2Z A;  1XFZ A;  3HY9 A;  5CUH A;  1SMP A;  5I12 A;  1O0T A;  1GXD A;  1XFU A;  1BIW A;  4L63 A;  1H71 P;  4JA1 A;  2W0D A;  3B92 A;  3LMC A;  1UTT A;  2ERO A;  4J4M A;  3LUN A;  4GR0 A;  1C8T A;  4DPE A;  4PKR A;  2FV5 A;  4XBH A;  3L0V A;  1XUC A;  2YB9 A;  2OY4 A;  3DTE A;  2J83 A;  2O36 A;  3LE9 A;  3EDG A;  1KUG A;  1XFW A;  2JT6 A;  2OVZ A;  1DTH A;  4ON1 A;  4FXY P;  3LKA A;  2ERP A;  1DMT A;  1SAT A;  5L7F A;  5D1U A;  1O0Q A;  1IAB A;  1G49 A;  3CKI A;  1IAA A;  3LK8 A;  1CXV A;  1EAK A;  2MLS A;  1HTD A;  3AIG A;  2D1O A;  1JAQ A;  4GWM A;  1G12 A;  3HBV P;  5D7W A;  3WV3 A;  1D5J A;  1R55 A;  2DDY A;  1JAO A;  4DV8 A;  4PKV A;  2AIG P;  2PJT A;  1SLN A;  2QPJ A;  3RTS A;  2W12 A;  2CKI A;  3LEA A;  3G5C A;  4GQL A;  1RM8 A;  5I0L A;  3ZVS A;  2POJ A;  4GF1 A;  3BA0 A;  1Q3A A;  1OM8 A;  1GE7 A;  3DPF A;  1SLM A;  4QKZ A;  1HV5 A;  1IAC A;  3TSK A;  1SU3 A;  4WKE A;  5D3C A;  1IAG A;  1UEA A;  2K9C A;  3HDA P;  4EFS A;  3VTG A;  3KRY A;  4G9L A;  3I7G A;  3V96 B;  2JIH A;  4IN9 A;  3KWV C;  3KME A;  1GE6 A;  1JK3 A;  1JIZ A;  3WV2 A;  1CAQ A;  4FVL A;  4HMA A;  1HOV A;  2X3B A;  3EDI A;  1XUD A;  2JT5 A;  1CGL A;  1QIA A;  1BKC E;  1BQO A;  1AST A;  4PKU A;  1HY7 A;  1CGE A;  1PWP A;  3DTI A;  2OW0 A;  2OXW A;  5B5O A;  2HU6 A;  3E8R A;  1BQQ M;  4H1Q A;  4WKI A;  5I43 A;  2ERQ A;  4JIJ A;  5D1T A;  1MMP A;  1R1J A;  2OW1 A;  4A3W A;  4Q1L A;  5CXA A;  3DNG A;  3DPE A;  2KRJ A;  3LIL A;  1QUA A;  1KBC A;  1ZVX A;  2W13 A;  1I73 A;  4JPA A;  4PKS A;  2DW0 A;  2D1N A;  2Z2D A;  2MZH A;  1GKC A;  1CGF A;  4PKQ A;  2DW2 A;  1G05 A;  3Q2G A;  4AYK A;  1J7N A;  3DL1 A;  3F19 A;  1PWQ A;  2V4B A;  1MMQ A;  1XFV A;  5B5P A;  1YOU A;  1R54 A;  4L19 A;  1Z3J A;  3P1V A;  4WF6 A;  1OS9 A;  2OXU A;  2WOA A;  3LQ0 A;  1S4B P;  1K7I A;  1JIW P;  2J0T A;  5LAB A;  5BOY A;  5CZM A;  2FV9 A;  2X3A A;  1JH1 A;  2Y6C A;  1C7K A;  1MMR A;  3LIR A;  2RJP A;  1K7G A;  1XFX A;  4I03 A;  2JNP A;  1GE5 A;  1JKY A;  2MLR A;  3GBO A;  1FLS A;  1K7Q A;  2MZE A;  3ZXH A;  1UMS A;  1WNI A;  4AXQ A;  3K7N A;  3LJG A;  1UTZ A;  1EB6 A;  3HB2 P;  4HX3 A;  1XUR A;  3AYK A;  4R3V A;  3TS4 A;  1G4K A;  5I2Z A;  5BPA A;  4PKT A;  2A8H A;  1KUH A;  3KEK A;  5BOT A;  4L6T A;  1USN A;  4G0D A;  2W15 A;  1ND1 A;  3DSL A;  1QIB A;  2OY2 A;  4FXQ A;  966C A;  1BM6 A;  3UVC A;  1OMJ A;  2XS3 A;  2WO9 A;  4PKW A;  1KAP P;  1D8F A;  2MZI A;  1ZP5 A;  3KMC A;  3WV1 A;  1GO7 P;  3LJT A;  4H82 A;  5H8X A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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