3F1AA

Crystal structure of the catalytic domain of human mmp12 complexed with the inhibitor n-(2-nitroso-2-oxoethyl)benzenesulfonamide
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
158
structure length
158
Chain Sequence
GPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Exploring the subtleties of drug-receptor interactions: the case of matrix metalloproteinases.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Macrophage metalloelastase
total genus 45
structure length 158
sequence length 158
ec nomenclature ec 3.4.24.65: Macrophage elastase.
pdb deposition date 2008-10-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 3f1aA00
2D1OA 1ZTQA 1G9KA 3B2ZA 1OS2A 1ATLA 4FXYP 4GWMA 2RJPA 1FM1A 1BUDA 3SHIA 4FXQA 3DWBA 1KAPP 3LGPA 3TSKA 2OZRA 3K7LA 1CGFA 4DD8A 1WNIA 4L63A 1I76A 4XM7A 1FLSA 2A8HA 5D1SA 1CXVA 3DL1A 1BKCE 4GUYA 3HBVP 2KRJA 3E8RA 1BM6A 2ERPA 1GE6A 2E3XA 1HFCA 1PWVA 2DDFA 1D8MA 1CIZA 1ROSA 1GO7P 830CA 4AYKA 4JP4A 1CGLA 1GE7A 2SRTA 1MMRA 5CXAA 1ZP5A 3KMEA 3TVCA 2OW1A 4R3VA 3EWJA 1D8FA 4JQGA 2OXWA 3HBUP 1UTTA 4H76A 1XFYA 3LMCA 2O3EA 3GBOA 3BA0A 1OM7A 4XM8A 1CQRA 1IABA 5H8XA 1KUIA 2AIGP 1DMTA 1JANA 3KWVC 2CLTA 1RM8A 4G9LA 2W0DA 1ZXVA 3RTSA 1CK7A 2JSDA 5D7WA 4CTHA 1BZSA 5LABA 4H30A 1QICA 1MMQA 1QIAA 2DDYA 4WKIA 5I3MA 2W14A 1BIWA 1QJJA 1YQYA 4H84A 3LUNA 1C7KA 4IJOA 1H71P 2YIGA 1G49A 4H1QA 3EDHA 3I7GA 2OXZA 3LJGA 3ZUKA 3LQ0A 1O0TA 3B92A 2WOAA 1HFSA 5CUHA 1G05A 1JAQA 5I4OA 1L6JA 3L0VA 2OI0A 3LKAA 3LQBA 1PWPA 3TT4A 2OW2A 1KUFA 3F1AA 3F19A 5B5OA 1I1IP 2JT5A 3KHIA 3HDBA 4DPEA 4DF9A 2PJTA 1R1IA 1UMTA 966CA 2XS4A 2V4BA 5L79A 1BUVM 5I43A 1XFWA 2RJQA 2J83A 2DW0A 1CGEA 1ZVXA 3EDIA 2ERQA 3OHLA 2Y6DA 2YB9A 1D7XA 1R1JA 2AYKA 2X3CA 1YCMA 1JK3A 1CAQA 2DW1A 2POJA 3AIGA 4AXQA 3KMCA 4H2EA 2OW0A 2JT6A 1SU3A 3RTTA 1R1HA 4WF6A 3Q2GA 4GWNA 456CA 4HMAA 5BPAA 3KECA 1IAAA 4L19A 4PKTA 4GF1A 5D1UA 3F18A 2D1NA 3UVCA 5CZMA 3LILA 1BSWA 4DV8A 5D3CA 2MLRA 3LJZA 2FV9A 4GQLA 4PKRA 5I2ZA 5BOTA 4WKEA 1G4KA 4XBHA 2E2DA 1SMPA 3U1RA 2JNPA 1EAKA 4A3WA 3P24A 5BOYA 1QIBA 1A85A 4ZR5A 1IAEA 4J4MA 1QUAA 3LIRA 1OM8A 4JIJA 3HY9A 1KUKA 1PWUA 1OM6A 2Z2DA 1R55A 1ZXCA 1JIZA 1Y8JA 1K7QA 3G42A 2W12A 1XFUA 1AKLA 1ZS0A 1HTDA 4L6TA 1BQQM 4IUWA 3AYUA 3VTGA 4AIGA 4ON1A 4XCTA 1Y93A 2WO9A 4H82A 1PWQA 4JA1A 4HX3A 2MLSA 3HYGA 2MZIA 3DPFA 1JKYA 2JIHA 1BKCA 3LJTA 3HDAP 4GR3A 2EROA 3LEAA 1EUBA 3G5CA 3I7IA 4PKSA 4PKWA 1GKCA 1XUCA 2Y6CA 1K7GA 3LUMA 2WO8A 3Q2HA 3TS4A 1IAGA 1FBLA 1UEAA 1C3IA 3P1VA 1YOUA 1MNCA 3ZVSA 1OO9A 4H49A 4EFSA 3USNA 2QPJA 1AYKA 1SRPA 1XURA 1OMJA 3VI1A 3ELMA 2J0TA 1RMZA 3LIKA 1JAOA 1IADA 1BQOA 2K2GA 1C8TA 3KEJA 3HB2P 1HV5A 5JMYA 1D5JA 3LK8A 3K7NA 3V96B 3KEKA 5L7FA 2CKIA 2TCLA 4ILWD 3L0TA 3N2VA 3N2UA 2OVXA 2O36A 4FU4A 3EHYA 1KBCA 1USNA 3ZXHA 1GO8P 4I03A 3WV2A 4WZVA 4I35A 1Q3AA 1SATA 1XFZA 1Y0VA 3F16A 2HU6A 3DNGA 2OXUA 3F17A 2N8RA 4A7BA 3MA2A 2OY4A 1GKDA 1JAPA 1I73A 5B5PA 3O64A 1AF0A 3EHXA 3LE9A 1GE5A 1JJ9A 2MZEA 2USNA 1KUHA 3O2XA 2MZHA 4GR8A 4Q1LA 2K9CA 3EDGA 3DSLA 1JH1A 4QKZA 3HY7A 1QJIA 1YP1A 1KUGA 1EB6A 1DTHA 1OS9A 1J7NA 1XFXA 4FVLA 1SLNA 4PKUA 2I47A 4G0DA 4IN9A 1G12A 4H3XA 4WK7A 1R54A 2X3BA 1SLMA 4AUOA 1MMBA 1HY7A 2OVZA 2W13A 4PKVA 4XM6A 3EDZA 1JIWP 1IACA 2X7MA 2OW9A 3WV1A 3AYKA 1UTZA 1PWWA 1S4BP 2XS3A 3NX7A 5I0LA 1K7IA 1HOVA 1A86A 1GXDA 4PKQA 1O0QA 4GR0A 3B8ZA 3WV3A 1B8YA 5I12A 2W15A 5D2BA 2OY2A 2L0RA 1Z3JA 1UMSA 1B3DA 3OHOA 5D1TA 1MMPA 2FV5A 1BKCI 1XFVA 1ASTA 3DPEA 3CKIA 1ND1A 3F15A 3KRYA 2X3AA 2DW2A 4JPAA 1XUDA
chains in the Genus database with same CATH superfamily
2D1OA 1ZTQA 1G9KA 3B2ZA 1OS2A 1ATLA 4FXYP 4GWMA 2RJPA 1FM1A 1BUDA 3SHIA 4FXQA 3DWBA 1KAPP 3LGPA 3TSKA 2OZRA 3K7LA 1CGFA 4DD8A 1WNIA 4L63A 1I76A 4XM7A 1FLSA 2A8HA 5D1SA 1CXVA 3DL1A 1BKCE 4GUYA 3HBVP 2KRJA 3E8RA 1BM6A 2ERPA 1GE6A 2E3XA 1HFCA 1PWVA 2DDFA 1D8MA 1CIZA 1ROSA 1GO7P 830CA 4AYKA 4JP4A 1CGLA 1GE7A 2SRTA 1MMRA 5CXAA 1ZP5A 3KMEA 3TVCA 2OW1A 4R3VA 3EWJA 1D8FA 4JQGA 2OXWA 3HBUP 1UTTA 4H76A 1XFYA 3LMCA 2O3EA 3GBOA 3BA0A 1OM7A 4XM8A 1CQRA 1IABA 5H8XA 1KUIA 2AIGP 1DMTA 1JANA 3KWVC 2CLTA 1RM8A 3DTIA 4G9LA 2W0DA 1ZXVA 3RTSA 1CK7A 2JSDA 5D7WA 4CTHA 1BZSA 5LABA 4H30A 1QICA 1MMQA 1QIAA 2DDYA 4WKIA 5I3MA 2W14A 1BIWA 1QJJA 1YQYA 4H84A 3LUNA 1C7KA 4IJOA 1H71P 2YIGA 1G49A 4H1QA 3EDHA 3I7GA 2OXZA 3LJGA 3ZUKA 3LQ0A 1O0TA 3B92A 2WOAA 1HFSA 5CUHA 1G05A 1JAQA 5I4OA 1L6JA 3L0VA 2OI0A 3LKAA 3LQBA 1PWPA 3TT4A 2OW2A 1KUFA 3F1AA 3F19A 1XM5A 5B5OA 1I1IP 2JT5A 3KHIA 3HDBA 4DPEA 4DF9A 2PJTA 1R1IA 1UMTA 966CA 2XS4A 2V4BA 5L79A 1BUVM 5I43A 1XFWA 2RJQA 2J83A 2DW0A 1CGEA 1ZVXA 3EDIA 2ERQA 3OHLA 2Y6DA 2YB9A 1D7XA 1R1JA 2AYKA 2X3CA 1YCMA 1JK3A 1CAQA 2DW1A 2POJA 3AIGA 4AXQA 3KMCA 4H2EA 2OW0A 2JT6A 1SU3A 3RTTA 1R1HA 4WF6A 3Q2GA 4GWNA 456CA 4HMAA 5BPAA 3KECA 1IAAA 4L19A 4PKTA 4GF1A 5D1UA 3F18A 4L7AA 2D1NA 3UVCA 5CZMA 3LILA 1BSWA 4DV8A 5D3CA 2MLRA 3LJZA 2FV9A 4GQLA 4PKRA 5I2ZA 5BOTA 4WKEA 1G4KA 4XBHA 2E2DA 1SMPA 3U1RA 2JNPA 1EAKA 4A3WA 3P24A 5BOYA 1QIBA 1A85A 4ZR5A 1IAEA 4J4MA 1QUAA 3LIRA 1OM8A 4JIJA 3HY9A 1KUKA 1PWUA 1OM6A 2Z2DA 3DTEA 1R55A 1ZXCA 1JIZA 1Y8JA 1K7QA 3G42A 2W12A 1XFUA 1AKLA 1ZS0A 1HTDA 4L6TA 1BQQM 4IUWA 3AYUA 3VTGA 4AIGA 4ON1A 4XCTA 1Y93A 2WO9A 4H82A 1PWQA 4JA1A 4HX3A 2MLSA 3HYGA 2MZIA 3DPFA 1JKYA 2JIHA 1BKCA 3LJTA 3HDAP 4GR3A 2EROA 3LEAA 1EUBA 3G5CA 3I7IA 4PKSA 4PKWA 1GKCA 1XUCA 2Y6CA 1K7GA 3LUMA 2WO8A 3Q2HA 3TS4A 1IAGA 1FBLA 1UEAA 1C3IA 3P1VA 1YOUA 1MNCA 3ZVSA 1OO9A 4H49A 4EFSA 3USNA 1XAXA 2QPJA 1AYKA 1SRPA 1XURA 1OMJA 3VI1A 3ELMA 2J0TA 1RMZA 3LIKA 1JAOA 1IADA 1BQOA 2K2GA 1C8TA 3KEJA 3HB2P 1HV5A 5JMYA 1D5JA 3LK8A 3K7NA 3V96B 3KEKA 5L7FA 2CKIA 2TCLA 4ILWD 3DTKA 3L0TA 3N2VA 3N2UA 2OVXA 2O36A 4FU4A 3EHYA 1OZ9A 1KBCA 1USNA 3ZXHA 1GO8P 4I03A 3WV2A 4WZVA 4I35A 1Q3AA 1SATA 1XFZA 1Y0VA 3F16A 2HU6A 3DNGA 2OXUA 3F17A 2N8RA 4A7BA 3MA2A 2OY4A 1GKDA 1JAPA 1I73A 5B5PA 3O64A 1AF0A 3EHXA 3LE9A 1GE5A 1JJ9A 2MZEA 2USNA 1KUHA 3O2XA 2MZHA 4GR8A 4Q1LA 2K9CA 3EDGA 3DSLA 1JH1A 4QKZA 3HY7A 1QJIA 1YP1A 1KUGA 1EB6A 1DTHA 1OS9A 1J7NA 1XFXA 4FVLA 1SLNA 4PKUA 2I47A 4G0DA 4IN9A 1G12A 4H3XA 4WK7A 1R54A 2X3BA 1SLMA 4AUOA 1MMBA 1HY7A 2OVZA 2W13A 4PKVA 4XM6A 3EDZA 1JIWP 1IACA 2X7MA 2OW9A 3WV1A 3AYKA 1UTZA 2YUFA 1PWWA 1S4BP 1TVIA 2XS3A 3NX7A 5I0LA 1K7IA 1HOVA 1A86A 1GXDA 4PKQA 1O0QA 4GR0A 3B8ZA 3WV3A 1B8YA 5I12A 2W15A 5D2BA 2OY2A 2L0RA 1Z3JA 1UMSA 1B3DA 3OHOA 5D1TA 1MMPA 2FV5A 1BKCI 1XFVA 1ASTA 3DPEA 3CKIA 1ND1A 3F15A 3KRYA 2X3AA 2DW2A 4JPAA 1XUDA
chains in the Genus database with same CATH topology
2D1OA 1ZTQA 1G9KA 3B2ZA 1OS2A 1ATLA 4FXYP 4GWMA 2RJPA 1FM1A 1BUDA 3SHIA 4FXQA 3DWBA 1KAPP 3LGPA 3TSKA 2OZRA 3K7LA 1CGFA 4DD8A 1WNIA 4L63A 1I76A 4XM7A 1FLSA 2A8HA 5D1SA 1CXVA 3DL1A 1BKCE 4GUYA 3HBVP 2KRJA 3E8RA 1BM6A 2ERPA 1GE6A 2E3XA 1HFCA 1PWVA 2DDFA 1D8MA 1CIZA 1ROSA 1GO7P 830CA 4AYKA 4JP4A 1CGLA 1GE7A 2SRTA 1MMRA 5CXAA 1ZP5A 3KMEA 3TVCA 2OW1A 4R3VA 3EWJA 1D8FA 4JQGA 2OXWA 3HBUP 1UTTA 4H76A 1XFYA 3LMCA 2O3EA 3GBOA 3BA0A 1OM7A 4XM8A 1CQRA 1IABA 5H8XA 1KUIA 2AIGP 1DMTA 1JANA 3KWVC 2CLTA 1RM8A 3DTIA 4G9LA 2W0DA 1ZXVA 3RTSA 1CK7A 2JSDA 5D7WA 4CTHA 1BZSA 5LABA 4H30A 1QICA 1MMQA 1QIAA 2DDYA 4WKIA 5I3MA 2W14A 1BIWA 1QJJA 1YQYA 4H84A 3LUNA 1C7KA 4IJOA 1H71P 2YIGA 1G49A 4H1QA 3EDHA 3I7GA 2OXZA 3LJGA 3ZUKA 3LQ0A 1O0TA 3B92A 2WOAA 1HFSA 5CUHA 1G05A 1JAQA 5I4OA 1L6JA 3L0VA 2OI0A 3LKAA 3LQBA 1PWPA 3TT4A 2OW2A 1KUFA 3F1AA 3F19A 5B5OA 1I1IP 2JT5A 3KHIA 3HDBA 4DPEA 4DF9A 2PJTA 1R1IA 1UMTA 966CA 2XS4A 2V4BA 5L79A 1BUVM 5I43A 1XFWA 2RJQA 2J83A 2DW0A 1CGEA 1ZVXA 3EDIA 2ERQA 3OHLA 2Y6DA 2YB9A 1D7XA 1R1JA 2AYKA 2X3CA 1YCMA 1JK3A 1CAQA 2DW1A 2POJA 3AIGA 4AXQA 3KMCA 4H2EA 2OW0A 2JT6A 1SU3A 3RTTA 1R1HA 4WF6A 3Q2GA 4GWNA 456CA 4HMAA 5BPAA 3KECA 1IAAA 4L19A 4PKTA 4GF1A 5D1UA 3F18A 4L7AA 2D1NA 3UVCA 5CZMA 3LILA 1BSWA 4DV8A 5D3CA 2MLRA 3LJZA 2FV9A 4GQLA 4PKRA 5I2ZA 5BOTA 4WKEA 1G4KA 4XBHA 2E2DA 1SMPA 3U1RA 2JNPA 1EAKA 4A3WA 3P24A 5BOYA 1QIBA 1A85A 4ZR5A 1IAEA 4J4MA 1QUAA 3LIRA 1OM8A 4JIJA 3HY9A 1KUKA 1PWUA 1OM6A 2Z2DA 3DTEA 1R55A 1ZXCA 1JIZA 1Y8JA 1K7QA 3G42A 2W12A 1XFUA 1AKLA 1ZS0A 1HTDA 4L6TA 1BQQM 4IUWA 3AYUA 3VTGA 4AIGA 4ON1A 4XCTA 1Y93A 2WO9A 4H82A 1PWQA 4JA1A 4HX3A 2MLSA 3HYGA 2MZIA 3DPFA 1JKYA 2JIHA 1BKCA 3LJTA 3HDAP 4GR3A 2EROA 3LEAA 1EUBA 3G5CA 3I7IA 4PKSA 4PKWA 1GKCA 1XUCA 2Y6CA 1K7GA 3LUMA 2WO8A 3Q2HA 3TS4A 1IAGA 1FBLA 1UEAA 1C3IA 3P1VA 1YOUA 1MNCA 3ZVSA 1OO9A 4H49A 4EFSA 3USNA 2QPJA 1AYKA 1SRPA 1XURA 1OMJA 3VI1A 3ELMA 2J0TA 1RMZA 3LIKA 1JAOA 1IADA 1BQOA 2K2GA 1C8TA 3KEJA 3HB2P 1HV5A 5JMYA 1D5JA 3LK8A 3K7NA 3V96B 3KEKA 5L7FA 2CKIA 2TCLA 4ILWD 3DTKA 3L0TA 3N2VA 3N2UA 2OVXA 2O36A 4FU4A 3EHYA 1KBCA 1USNA 3ZXHA 1GO8P 4I03A 3WV2A 4WZVA 4I35A 1Q3AA 1SATA 1XFZA 1Y0VA 3F16A 2HU6A 3DNGA 2OXUA 3F17A 2N8RA 4A7BA 3MA2A 2OY4A 1GKDA 1JAPA 1I73A 5B5PA 3O64A 1AF0A 3EHXA 3LE9A 1GE5A 1JJ9A 2MZEA 2USNA 1KUHA 3O2XA 2MZHA 4GR8A 4Q1LA 2K9CA 3EDGA 3DSLA 1JH1A 4QKZA 3HY7A 1QJIA 1YP1A 1KUGA 1EB6A 1DTHA 1OS9A 1J7NA 1XFXA 4FVLA 1SLNA 4PKUA 2I47A 4G0DA 4IN9A 1G12A 4H3XA 4WK7A 1R54A 2X3BA 1SLMA 4AUOA 1MMBA 1HY7A 2OVZA 2W13A 4PKVA 4XM6A 3EDZA 1JIWP 1IACA 2X7MA 2OW9A 3WV1A 3AYKA 1UTZA 2YUFA 1PWWA 1S4BP 2XS3A 3NX7A 5I0LA 1K7IA 1HOVA 1A86A 1GXDA 4PKQA 1O0QA 4GR0A 3B8ZA 3WV3A 1B8YA 5I12A 2W15A 5D2BA 2OY2A 2L0RA 1Z3JA 1UMSA 1B3DA 3OHOA 5D1TA 1MMPA 2FV5A 1BKCI 1XFVA 1ASTA 3DPEA 3CKIA 1ND1A 3F15A 3KRYA 2X3AA 2DW2A 4JPAA 1XUDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2D1O A;  1ZTQ A;  1G9K A;  3B2Z A;  1OS2 A;  1ATL A;  4FXY P;  4GWM A;  2RJP A;  1FM1 A;  1BUD A;  3SHI A;  4FXQ A;  3DWB A;  1KAP P;  3LGP A;  3TSK A;  2OZR A;  3K7L A;  1CGF A;  4DD8 A;  1WNI A;  4L63 A;  1I76 A;  4XM7 A;  1FLS A;  2A8H A;  5D1S A;  1CXV A;  3DL1 A;  1BKC E;  4GUY A;  3HBV P;  2KRJ A;  3E8R A;  1BM6 A;  2ERP A;  1GE6 A;  2E3X A;  1HFC A;  1PWV A;  2DDF A;  1D8M A;  1CIZ A;  1ROS A;  1GO7 P;  830C A;  4AYK A;  4JP4 A;  1CGL A;  1GE7 A;  2SRT A;  1MMR A;  5CXA A;  1ZP5 A;  3KME A;  3TVC A;  2OW1 A;  4R3V A;  3EWJ A;  1D8F A;  4JQG A;  2OXW A;  3HBU P;  1UTT A;  4H76 A;  1XFY A;  3LMC A;  2O3E A;  3GBO A;  3BA0 A;  1OM7 A;  4XM8 A;  1CQR A;  1IAB A;  5H8X A;  1KUI A;  2AIG P;  1DMT A;  1JAN A;  3KWV C;  2CLT A;  1RM8 A;  4G9L A;  2W0D A;  1ZXV A;  3RTS A;  1CK7 A;  2JSD A;  5D7W A;  4CTH A;  1BZS A;  5LAB A;  4H30 A;  1QIC A;  1MMQ A;  1QIA A;  2DDY A;  4WKI A;  5I3M A;  2W14 A;  1BIW A;  1QJJ A;  1YQY A;  4H84 A;  3LUN A;  1C7K A;  4IJO A;  1H71 P;  2YIG A;  1G49 A;  4H1Q A;  3EDH A;  3I7G A;  2OXZ A;  3LJG A;  3ZUK A;  3LQ0 A;  1O0T A;  3B92 A;  2WOA A;  1HFS A;  5CUH A;  1G05 A;  1JAQ A;  5I4O A;  1L6J A;  3L0V A;  2OI0 A;  3LKA A;  3LQB A;  1PWP A;  3TT4 A;  2OW2 A;  1KUF A;  3F1A A;  3F19 A;  5B5O A;  1I1I P;  2JT5 A;  3KHI A;  3HDB A;  4DPE A;  4DF9 A;  2PJT A;  1R1I A;  1UMT A;  966C A;  2XS4 A;  2V4B A;  5L79 A;  1BUV M;  5I43 A;  1XFW A;  2RJQ A;  2J83 A;  2DW0 A;  1CGE A;  1ZVX A;  3EDI A;  2ERQ A;  3OHL A;  2Y6D A;  2YB9 A;  1D7X A;  1R1J A;  2AYK A;  2X3C A;  1YCM A;  1JK3 A;  1CAQ A;  2DW1 A;  2POJ A;  3AIG A;  4AXQ A;  3KMC A;  4H2E A;  2OW0 A;  2JT6 A;  1SU3 A;  3RTT A;  1R1H A;  4WF6 A;  3Q2G A;  4GWN A;  456C A;  4HMA A;  5BPA A;  3KEC A;  1IAA A;  4L19 A;  4PKT A;  4GF1 A;  5D1U A;  3F18 A;  2D1N A;  3UVC A;  5CZM A;  3LIL A;  1BSW A;  4DV8 A;  5D3C A;  2MLR A;  3LJZ A;  2FV9 A;  4GQL A;  4PKR A;  5I2Z A;  5BOT A;  4WKE A;  1G4K A;  4XBH A;  2E2D A;  1SMP A;  3U1R A;  2JNP A;  1EAK A;  4A3W A;  3P24 A;  5BOY A;  1QIB A;  1A85 A;  4ZR5 A;  1IAE A;  4J4M A;  1QUA A;  3LIR A;  1OM8 A;  4JIJ A;  3HY9 A;  1KUK A;  1PWU A;  1OM6 A;  2Z2D A;  1R55 A;  1ZXC A;  1JIZ A;  1Y8J A;  1K7Q A;  3G42 A;  2W12 A;  1XFU A;  1AKL A;  1ZS0 A;  1HTD A;  4L6T A;  1BQQ M;  4IUW A;  3AYU A;  3VTG A;  4AIG A;  4ON1 A;  4XCT A;  1Y93 A;  2WO9 A;  4H82 A;  1PWQ A;  4JA1 A;  4HX3 A;  2MLS A;  3HYG A;  2MZI A;  3DPF A;  1JKY A;  2JIH A;  1BKC A;  3LJT A;  3HDA P;  4GR3 A;  2ERO A;  3LEA A;  1EUB A;  3G5C A;  3I7I A;  4PKS A;  4PKW A;  1GKC A;  1XUC A;  2Y6C A;  1K7G A;  3LUM A;  2WO8 A;  3Q2H A;  3TS4 A;  1IAG A;  1FBL A;  1UEA A;  1C3I A;  3P1V A;  1YOU A;  1MNC A;  3ZVS A;  1OO9 A;  4H49 A;  4EFS A;  3USN A;  2QPJ A;  1AYK A;  1SRP A;  1XUR A;  1OMJ A;  3VI1 A;  3ELM A;  2J0T A;  1RMZ A;  3LIK A;  1JAO A;  1IAD A;  1BQO A;  2K2G A;  1C8T A;  3KEJ A;  3HB2 P;  1HV5 A;  5JMY A;  1D5J A;  3LK8 A;  3K7N A;  3V96 B;  3KEK A;  5L7F A;  2CKI A;  2TCL A;  4ILW D;  3L0T A;  3N2V A;  3N2U A;  2OVX A;  2O36 A;  4FU4 A;  3EHY A;  1KBC A;  1USN A;  3ZXH A;  1GO8 P;  4I03 A;  3WV2 A;  4WZV A;  4I35 A;  1Q3A A;  1SAT A;  1XFZ A;  1Y0V A;  3F16 A;  2HU6 A;  3DNG A;  2OXU A;  3F17 A;  2N8R A;  4A7B A;  3MA2 A;  2OY4 A;  1GKD A;  1JAP A;  1I73 A;  5B5P A;  3O64 A;  1AF0 A;  3EHX A;  3LE9 A;  1GE5 A;  1JJ9 A;  2MZE A;  2USN A;  1KUH A;  3O2X A;  2MZH A;  4GR8 A;  4Q1L A;  2K9C A;  3EDG A;  3DSL A;  1JH1 A;  4QKZ A;  3HY7 A;  1QJI A;  1YP1 A;  1KUG A;  1EB6 A;  1DTH A;  1OS9 A;  1J7N A;  1XFX A;  4FVL A;  1SLN A;  4PKU A;  2I47 A;  4G0D A;  4IN9 A;  1G12 A;  4H3X A;  4WK7 A;  1R54 A;  2X3B A;  1SLM A;  4AUO A;  1MMB A;  1HY7 A;  2OVZ A;  2W13 A;  4PKV A;  4XM6 A;  3EDZ A;  1JIW P;  1IAC A;  2X7M A;  2OW9 A;  3WV1 A;  3AYK A;  1UTZ A;  1PWW A;  1S4B P;  2XS3 A;  3NX7 A;  5I0L A;  1K7I A;  1HOV A;  1A86 A;  1GXD A;  4PKQ A;  1O0Q A;  4GR0 A;  3B8Z A;  3WV3 A;  1B8Y A;  5I12 A;  2W15 A;  5D2B A;  2OY2 A;  2L0R A;  1Z3J A;  1UMS A;  1B3D A;  3OHO A;  5D1T A;  1MMP A;  2FV5 A;  1BKC I;  1XFV A;  1AST A;  3DPE A;  3CKI A;  1ND1 A;  3F15 A;  3KRY A;  2X3A A;  2DW2 A;  4JPA A;  1XUD A; 
#chains in the Genus database with same CATH topology
 2D1O A;  1ZTQ A;  1G9K A;  3B2Z A;  1OS2 A;  1ATL A;  4FXY P;  4GWM A;  2RJP A;  1FM1 A;  1BUD A;  3SHI A;  4FXQ A;  3DWB A;  1KAP P;  3LGP A;  3TSK A;  2OZR A;  3K7L A;  1CGF A;  4DD8 A;  1WNI A;  4L63 A;  1I76 A;  4XM7 A;  1FLS A;  2A8H A;  5D1S A;  1CXV A;  3DL1 A;  1BKC E;  4GUY A;  3HBV P;  2KRJ A;  3E8R A;  1BM6 A;  2ERP A;  1GE6 A;  2E3X A;  1HFC A;  1PWV A;  2DDF A;  1D8M A;  1CIZ A;  1ROS A;  1GO7 P;  830C A;  4AYK A;  4JP4 A;  1CGL A;  1GE7 A;  2SRT A;  1MMR A;  5CXA A;  1ZP5 A;  3KME A;  3TVC A;  2OW1 A;  4R3V A;  3EWJ A;  1D8F A;  4JQG A;  2OXW A;  3HBU P;  1UTT A;  4H76 A;  1XFY A;  3LMC A;  2O3E A;  3GBO A;  3BA0 A;  1OM7 A;  4XM8 A;  1CQR A;  1IAB A;  5H8X A;  1KUI A;  2AIG P;  1DMT A;  1JAN A;  3KWV C;  2CLT A;  1RM8 A;  3DTI A;  4G9L A;  2W0D A;  1ZXV A;  3RTS A;  1CK7 A;  2JSD A;  5D7W A;  4CTH A;  1BZS A;  5LAB A;  4H30 A;  1QIC A;  1MMQ A;  1QIA A;  2DDY A;  4WKI A;  5I3M A;  2W14 A;  1BIW A;  1QJJ A;  1YQY A;  4H84 A;  3LUN A;  1C7K A;  4IJO A;  1H71 P;  2YIG A;  1G49 A;  4H1Q A;  3EDH A;  3I7G A;  2OXZ A;  3LJG A;  3ZUK A;  3LQ0 A;  1O0T A;  3B92 A;  2WOA A;  1HFS A;  5CUH A;  1G05 A;  1JAQ A;  5I4O A;  1L6J A;  3L0V A;  2OI0 A;  3LKA A;  3LQB A;  1PWP A;  3TT4 A;  2OW2 A;  1KUF A;  3F1A A;  3F19 A;  1XM5 A;  5B5O A;  1I1I P;  2JT5 A;  3KHI A;  3HDB A;  4DPE A;  4DF9 A;  2PJT A;  1R1I A;  1UMT A;  966C A;  2XS4 A;  2V4B A;  5L79 A;  1BUV M;  5I43 A;  1XFW A;  2RJQ A;  2J83 A;  2DW0 A;  1CGE A;  1ZVX A;  3EDI A;  2ERQ A;  3OHL A;  2Y6D A;  2YB9 A;  1D7X A;  1R1J A;  2AYK A;  2X3C A;  1YCM A;  1JK3 A;  1CAQ A;  2DW1 A;  2POJ A;  3AIG A;  4AXQ A;  3KMC A;  4H2E A;  2OW0 A;  2JT6 A;  1SU3 A;  3RTT A;  1R1H A;  4WF6 A;  3Q2G A;  4GWN A;  456C A;  4HMA A;  5BPA A;  3KEC A;  1IAA A;  4L19 A;  4PKT A;  4GF1 A;  5D1U A;  3F18 A;  4L7A A;  2D1N A;  3UVC A;  5CZM A;  3LIL A;  1BSW A;  4DV8 A;  5D3C A;  2MLR A;  3LJZ A;  2FV9 A;  4GQL A;  4PKR A;  5I2Z A;  5BOT A;  4WKE A;  1G4K A;  4XBH A;  2E2D A;  1SMP A;  3U1R A;  2JNP A;  1EAK A;  4A3W A;  3P24 A;  5BOY A;  1QIB A;  1A85 A;  4ZR5 A;  1IAE A;  4J4M A;  1QUA A;  3LIR A;  1OM8 A;  4JIJ A;  3HY9 A;  1KUK A;  1PWU A;  1OM6 A;  2Z2D A;  3DTE A;  1R55 A;  1ZXC A;  1JIZ A;  1Y8J A;  1K7Q A;  3G42 A;  2W12 A;  1XFU A;  1AKL A;  1ZS0 A;  1HTD A;  4L6T A;  1BQQ M;  4IUW A;  3AYU A;  3VTG A;  4AIG A;  4ON1 A;  4XCT A;  1Y93 A;  2WO9 A;  4H82 A;  1PWQ A;  4JA1 A;  4HX3 A;  2MLS A;  3HYG A;  2MZI A;  3DPF A;  1JKY A;  2JIH A;  1BKC A;  3LJT A;  3HDA P;  4GR3 A;  2ERO A;  3LEA A;  1EUB A;  3G5C A;  3I7I A;  4PKS A;  4PKW A;  1GKC A;  1XUC A;  2Y6C A;  1K7G A;  3LUM A;  2WO8 A;  3Q2H A;  3TS4 A;  1IAG A;  1FBL A;  1UEA A;  1C3I A;  3P1V A;  1YOU A;  1MNC A;  3ZVS A;  1OO9 A;  4H49 A;  4EFS A;  3USN A;  1XAX A;  2QPJ A;  1AYK A;  1SRP A;  1XUR A;  1OMJ A;  3VI1 A;  3ELM A;  2J0T A;  1RMZ A;  3LIK A;  1JAO A;  1IAD A;  1BQO A;  2K2G A;  1C8T A;  3KEJ A;  3HB2 P;  1HV5 A;  5JMY A;  1D5J A;  3LK8 A;  3K7N A;  3V96 B;  3KEK A;  5L7F A;  2CKI A;  2TCL A;  4ILW D;  3DTK A;  3L0T A;  3N2V A;  3N2U A;  2OVX A;  2O36 A;  4FU4 A;  3EHY A;  1OZ9 A;  1KBC A;  1USN A;  3ZXH A;  1GO8 P;  4I03 A;  3WV2 A;  4WZV A;  4I35 A;  1Q3A A;  1SAT A;  1XFZ A;  1Y0V A;  3F16 A;  2HU6 A;  3DNG A;  2OXU A;  3F17 A;  2N8R A;  4A7B A;  3MA2 A;  2OY4 A;  1GKD A;  1JAP A;  1I73 A;  5B5P A;  3O64 A;  1AF0 A;  3EHX A;  3LE9 A;  1GE5 A;  1JJ9 A;  2MZE A;  2USN A;  1KUH A;  3O2X A;  2MZH A;  4GR8 A;  4Q1L A;  2K9C A;  3EDG A;  3DSL A;  1JH1 A;  4QKZ A;  3HY7 A;  1QJI A;  1YP1 A;  1KUG A;  1EB6 A;  1DTH A;  1OS9 A;  1J7N A;  1XFX A;  4FVL A;  1SLN A;  4PKU A;  2I47 A;  4G0D A;  4IN9 A;  1G12 A;  4H3X A;  4WK7 A;  1R54 A;  2X3B A;  1SLM A;  4AUO A;  1MMB A;  1HY7 A;  2OVZ A;  2W13 A;  4PKV A;  4XM6 A;  3EDZ A;  1JIW P;  1IAC A;  2X7M A;  2OW9 A;  3WV1 A;  3AYK A;  1UTZ A;  2YUF A;  1PWW A;  1S4B P;  1TVI A;  2XS3 A;  3NX7 A;  5I0L A;  1K7I A;  1HOV A;  1A86 A;  1GXD A;  4PKQ A;  1O0Q A;  4GR0 A;  3B8Z A;  3WV3 A;  1B8Y A;  5I12 A;  2W15 A;  5D2B A;  2OY2 A;  2L0R A;  1Z3J A;  1UMS A;  1B3D A;  3OHO A;  5D1T A;  1MMP A;  2FV5 A;  1BKC I;  1XFV A;  1AST A;  3DPE A;  3CKI A;  1ND1 A;  3F15 A;  3KRY A;  2X3A A;  2DW2 A;  4JPA A;  1XUD A; 
#chains in the Genus database with same CATH homology
 2D1O A;  1ZTQ A;  1G9K A;  3B2Z A;  1OS2 A;  1ATL A;  4FXY P;  4GWM A;  2RJP A;  1FM1 A;  1BUD A;  3SHI A;  4FXQ A;  3DWB A;  1KAP P;  3LGP A;  3TSK A;  2OZR A;  3K7L A;  1CGF A;  4DD8 A;  1WNI A;  4L63 A;  1I76 A;  4XM7 A;  1FLS A;  2A8H A;  5D1S A;  1CXV A;  3DL1 A;  1BKC E;  4GUY A;  3HBV P;  2KRJ A;  3E8R A;  1BM6 A;  2ERP A;  1GE6 A;  2E3X A;  1HFC A;  1PWV A;  2DDF A;  1D8M A;  1CIZ A;  1ROS A;  1GO7 P;  830C A;  4AYK A;  4JP4 A;  1CGL A;  1GE7 A;  2SRT A;  1MMR A;  5CXA A;  1ZP5 A;  3KME A;  3TVC A;  2OW1 A;  4R3V A;  3EWJ A;  1D8F A;  4JQG A;  2OXW A;  3HBU P;  1UTT A;  4H76 A;  1XFY A;  3LMC A;  2O3E A;  3GBO A;  3BA0 A;  1OM7 A;  4XM8 A;  1CQR A;  1IAB A;  5H8X A;  1KUI A;  2AIG P;  1DMT A;  1JAN A;  3KWV C;  2CLT A;  1RM8 A;  3DTI A;  4G9L A;  2W0D A;  1ZXV A;  3RTS A;  1CK7 A;  2JSD A;  5D7W A;  4CTH A;  1BZS A;  5LAB A;  4H30 A;  1QIC A;  1MMQ A;  1QIA A;  2DDY A;  4WKI A;  5I3M A;  2W14 A;  1BIW A;  1QJJ A;  1YQY A;  4H84 A;  3LUN A;  1C7K A;  4IJO A;  1H71 P;  2YIG A;  1G49 A;  4H1Q A;  3EDH A;  3I7G A;  2OXZ A;  3LJG A;  3ZUK A;  3LQ0 A;  1O0T A;  3B92 A;  2WOA A;  1HFS A;  5CUH A;  1G05 A;  1JAQ A;  5I4O A;  1L6J A;  3L0V A;  2OI0 A;  3LKA A;  3LQB A;  1PWP A;  3TT4 A;  2OW2 A;  1KUF A;  3F1A A;  3F19 A;  5B5O A;  1I1I P;  2JT5 A;  3KHI A;  3HDB A;  4DPE A;  4DF9 A;  2PJT A;  1R1I A;  1UMT A;  966C A;  2XS4 A;  2V4B A;  5L79 A;  1BUV M;  5I43 A;  1XFW A;  2RJQ A;  2J83 A;  2DW0 A;  1CGE A;  1ZVX A;  3EDI A;  2ERQ A;  3OHL A;  2Y6D A;  2YB9 A;  1D7X A;  1R1J A;  2AYK A;  2X3C A;  1YCM A;  1JK3 A;  1CAQ A;  2DW1 A;  2POJ A;  3AIG A;  4AXQ A;  3KMC A;  4H2E A;  2OW0 A;  2JT6 A;  1SU3 A;  3RTT A;  1R1H A;  4WF6 A;  3Q2G A;  4GWN A;  456C A;  4HMA A;  5BPA A;  3KEC A;  1IAA A;  4L19 A;  4PKT A;  4GF1 A;  5D1U A;  3F18 A;  4L7A A;  2D1N A;  3UVC A;  5CZM A;  3LIL A;  1BSW A;  4DV8 A;  5D3C A;  2MLR A;  3LJZ A;  2FV9 A;  4GQL A;  4PKR A;  5I2Z A;  5BOT A;  4WKE A;  1G4K A;  4XBH A;  2E2D A;  1SMP A;  3U1R A;  2JNP A;  1EAK A;  4A3W A;  3P24 A;  5BOY A;  1QIB A;  1A85 A;  4ZR5 A;  1IAE A;  4J4M A;  1QUA A;  3LIR A;  1OM8 A;  4JIJ A;  3HY9 A;  1KUK A;  1PWU A;  1OM6 A;  2Z2D A;  3DTE A;  1R55 A;  1ZXC A;  1JIZ A;  1Y8J A;  1K7Q A;  3G42 A;  2W12 A;  1XFU A;  1AKL A;  1ZS0 A;  1HTD A;  4L6T A;  1BQQ M;  4IUW A;  3AYU A;  3VTG A;  4AIG A;  4ON1 A;  4XCT A;  1Y93 A;  2WO9 A;  4H82 A;  1PWQ A;  4JA1 A;  4HX3 A;  2MLS A;  3HYG A;  2MZI A;  3DPF A;  1JKY A;  2JIH A;  1BKC A;  3LJT A;  3HDA P;  4GR3 A;  2ERO A;  3LEA A;  1EUB A;  3G5C A;  3I7I A;  4PKS A;  4PKW A;  1GKC A;  1XUC A;  2Y6C A;  1K7G A;  3LUM A;  2WO8 A;  3Q2H A;  3TS4 A;  1IAG A;  1FBL A;  1UEA A;  1C3I A;  3P1V A;  1YOU A;  1MNC A;  3ZVS A;  1OO9 A;  4H49 A;  4EFS A;  3USN A;  2QPJ A;  1AYK A;  1SRP A;  1XUR A;  1OMJ A;  3VI1 A;  3ELM A;  2J0T A;  1RMZ A;  3LIK A;  1JAO A;  1IAD A;  1BQO A;  2K2G A;  1C8T A;  3KEJ A;  3HB2 P;  1HV5 A;  5JMY A;  1D5J A;  3LK8 A;  3K7N A;  3V96 B;  3KEK A;  5L7F A;  2CKI A;  2TCL A;  4ILW D;  3DTK A;  3L0T A;  3N2V A;  3N2U A;  2OVX A;  2O36 A;  4FU4 A;  3EHY A;  1KBC A;  1USN A;  3ZXH A;  1GO8 P;  4I03 A;  3WV2 A;  4WZV A;  4I35 A;  1Q3A A;  1SAT A;  1XFZ A;  1Y0V A;  3F16 A;  2HU6 A;  3DNG A;  2OXU A;  3F17 A;  2N8R A;  4A7B A;  3MA2 A;  2OY4 A;  1GKD A;  1JAP A;  1I73 A;  5B5P A;  3O64 A;  1AF0 A;  3EHX A;  3LE9 A;  1GE5 A;  1JJ9 A;  2MZE A;  2USN A;  1KUH A;  3O2X A;  2MZH A;  4GR8 A;  4Q1L A;  2K9C A;  3EDG A;  3DSL A;  1JH1 A;  4QKZ A;  3HY7 A;  1QJI A;  1YP1 A;  1KUG A;  1EB6 A;  1DTH A;  1OS9 A;  1J7N A;  1XFX A;  4FVL A;  1SLN A;  4PKU A;  2I47 A;  4G0D A;  4IN9 A;  1G12 A;  4H3X A;  4WK7 A;  1R54 A;  2X3B A;  1SLM A;  4AUO A;  1MMB A;  1HY7 A;  2OVZ A;  2W13 A;  4PKV A;  4XM6 A;  3EDZ A;  1JIW P;  1IAC A;  2X7M A;  2OW9 A;  3WV1 A;  3AYK A;  1UTZ A;  2YUF A;  1PWW A;  1S4B P;  2XS3 A;  3NX7 A;  5I0L A;  1K7I A;  1HOV A;  1A86 A;  1GXD A;  4PKQ A;  1O0Q A;  4GR0 A;  3B8Z A;  3WV3 A;  1B8Y A;  5I12 A;  2W15 A;  5D2B A;  2OY2 A;  2L0R A;  1Z3J A;  1UMS A;  1B3D A;  3OHO A;  5D1T A;  1MMP A;  2FV5 A;  1BKC I;  1XFV A;  1AST A;  3DPE A;  3CKI A;  1ND1 A;  3F15 A;  3KRY A;  2X3A A;  2DW2 A;  4JPA A;  1XUD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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