3FDEA

Mouse uhrf1 sra domain bound with hemi-methylated cpg dna, crystal structure in space group c222(1) at 1.4 a resolution
Total Genus 62
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
62
sequence length
209
structure length
209
Chain Sequence
MPANHFGPIPGVPVGTMWRFRVQVSESGVHRPHVAGIHGRSNDGAYSLVLAGGYEDDVDNGNYFTYTGSGGRDLSGNKRTAGQSSDQKLTNNNRALALNCHSPINEKGAEAEDWRQGKPVRVVRNMKGGKHSKYAPAEGNRYDGIYKVVKYWPERGKSGFLVWRYLLRRDDTEPEPWTREGKDRTRQLGLTMQYPEGYLEALANKEKSR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Ligase
molecule keywords E3 ubiquitin-protein ligase UHRF1
publication title UHRF1, a modular multi-domain protein, regulates replication-coupled crosstalk between DNA methylation and histone modifications.
pubmed rcsb
source organism Mus musculus
total genus 62
structure length 209
sequence length 209
chains with identical sequence B
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2008-11-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02182 SAD_SRA SAD/SRA domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.280.10 Mainly Beta Roll PUA domain-like SRA-YDG 3fdeA01
4PW6A 3DWHA 2ZKGA 4PW7A 2ZO2B 3BI7A 3F8IA 2ZO0B 3CLZA 2ZKDA 2ZO1B 3F8JB 4PW5A 2ZKFA 2PB7A 3OLNA 4NJ5A 3FDEA 2ZKEA
chains in the Genus database with same CATH superfamily
4PW6A 3Q0CA 3DWHA 4R28A 4YGIA 4F0QA 2ZKGA 4RZLA 3BI7A 2ZO2B 3F8IA 4PW7A 4OC8A 2ZO0B 3Q0BX 3Q0FA 3CLZA 2ZKDA 2ZO1B 3F8JB 4PW5A 2ZKFA 2PB7A 3OLNA 3Q0DA 4NJ5A 3FDEA 4F0PA 2ZKEA
chains in the Genus database with same CATH topology
4PW6A 3DWHA 2ZKGA 4PW7A 2ZO2B 3BI7A 3F8IA 2ZO0B 3CLZA 2ZKDA 2ZO1B 3F8JB 4PW5A 2ZKFA 2PB7A 3OLNA 4NJ5A 3FDEA 2ZKEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4PW6 A;  3DWH A;  2ZKG A;  4PW7 A;  2ZO2 B;  3BI7 A;  3F8I A;  2ZO0 B;  3CLZ A;  2ZKD A;  2ZO1 B;  3F8J B;  4PW5 A;  2ZKF A;  2PB7 A;  3OLN A;  4NJ5 A;  3FDE A;  2ZKE A; 
#chains in the Genus database with same CATH topology
 4PW6 A;  3Q0C A;  3DWH A;  4R28 A;  4YGI A;  4F0Q A;  2ZKG A;  4RZL A;  3BI7 A;  2ZO2 B;  3F8I A;  4PW7 A;  4OC8 A;  2ZO0 B;  3Q0B X;  3Q0F A;  3CLZ A;  2ZKD A;  2ZO1 B;  3F8J B;  4PW5 A;  2ZKF A;  2PB7 A;  3OLN A;  3Q0D A;  4NJ5 A;  3FDE A;  4F0P A;  2ZKE A; 
#chains in the Genus database with same CATH homology
 4PW6 A;  3DWH A;  2ZKG A;  4PW7 A;  2ZO2 B;  3BI7 A;  3F8I A;  2ZO0 B;  3CLZ A;  2ZKD A;  2ZO1 B;  3F8J B;  4PW5 A;  2ZKF A;  2PB7 A;  3OLN A;  4NJ5 A;  3FDE A;  2ZKE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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