3FERA

Crystal structure of n-terminal actin-binding domain from human filamin b (tandem ch-domains). northeast structural genomics consortium target hr5571a.
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
sequence length
239
structure length
234
Chain Sequence
PWKKIQQNTFTRWCNEHLKCVNKRIGNLQTDLSDGLRLIALLEVLSQKRMYRKYHQRPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLVWTLILHYSISMPVWEDEGKQTPKQRLLGWIQNKIPYLPITNFNQNWQDGKALGALVDSCAPGLCPDWESWDPQKPVDNAREAMQQADDWLGVPQVITPEEIIHPDVDEHSVMTYLSQFPKAKLKPGAPLKPK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of n-terminal actin-binding domain from human filamin b (tandem ch-domains). northeast structural genomics consortium target hr5571a.
rcsb
molecule tags Actin binding protein
source organism Homo sapiens
molecule keywords Filamin-B
total genus 72
structure length 234
sequence length 239
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2008-11-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00307 CH Calponin homology (CH) domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.418.10 Mainly Alpha Orthogonal Bundle Actin-binding Protein, T-fimbrin; domain 1 Calponin-like domain 3ferA01
1.10.418.10 Mainly Alpha Orthogonal Bundle Actin-binding Protein, T-fimbrin; domain 1 Calponin-like domain 3ferA02
1WYLA 2EYIA 2DK9A 1SH6A 2VZIB 1PA7A 1WYOA 1RT8A 5BVRA 2JV9A 1WYPA 1BHDA 1BKRA 2RR8A 4Q59A 2QJZA 3KY9A 2D85A 2R0OA 5A37A 2L3GA 1V5KA 1WYNA 1P2XA 1PXYA 3JAKM 1UEGA 3F7PA 2R8UA 1VKAA 3HOPA 3CO1A 2WA5A 4EDMA 1SH5A 5A36A 4Q57B 2VZCA 2WFNA 1TJTA 1DXXA 1WYQA 2WA7A 1MB8A 3KMWB 2D87A 2E9KA 4TXKA 4EDNA 3JALM 4TXIA 1UJOA 1WYRA 4B7LA 2VZGB 5A38A 3FERA 2EYNA 1H67A 1WKUA 2K3SA 4EDLA 2K2RA 3KMUB 1AA2A 1WJOA 5J8EA 2D86A 3HOCA 1WIXA 2YRNA 3REPB 5A4BA 3HORA 5L0OA 1QAGA 2VZDA 1AOAA 3JARM 1WYMA 2EE7A 2D88A 1P5SA 4Q58A 2WA6A 2D89A 3I6XA 2QJXA
chains in the Genus database with same CATH superfamily
1WYLA 1EUVA 2HL8A 2EYIA 2DK9A 1SH6A 2HKPA 2VZIB 1PA7A 1WYOA 1RT8A 5BVRA 2JV9A 1WYPA 1BHDA 1BKRA 2RR8A 4Q59A 2QJZA 3KY9A 2D85A 2R0OA 2WDTA 5A37A 2L3GA 3VP7A 1V5KA 3EAYA 1WYNA 1P2XA 1PXYA 3JAKM 1UEGA 3F7PA 2R8UA 1VKAA 3HOPA 3CO1A 2WA5A 4EDMA 1SH5A 2EQOA 5A36A 4Q57B 2VZCA 5FMUA 2VE7A 4LVPA 2WFNA 1TJTA 1DXXA 1WYQA 2WA7A 1MB8A 3KMWB 2D87A 2E9KA 4TXKA 5FMTA 3JALM 4EDNA 4TXIA 1UJOA 1WYRA 2VE7C 4B7LA 2VZGB 5A38A 3FERA 2EYNA 4LVRA 1H67A 1WKUA 2K3SA 4DDPA 4EDLA 2K2RA 3KMUB 1AA2A 2HL9A 1WJOA 5J8EA 2WE6A 2D86A 3HOCA 1WIXA 2YRNA 3REPB 5A4BA 3HORA 5L0OA 1QAGA 2IGPA 2VZDA 1AOAA 3JARM 1WYMA 2EE7A 2D88A 1P5SA 4Q58A 2WA6A 2D89A 3I6XA 2QJXA
chains in the Genus database with same CATH topology
1WYLA 2EYIA 2DK9A 1SH6A 2VZIB 1PA7A 1WYOA 1RT8A 5BVRA 2JV9A 1WYPA 1BHDA 1BKRA 2RR8A 4Q59A 2QJZA 3KY9A 2D85A 2R0OA 5A37A 2L3GA 1V5KA 1WYNA 1P2XA 1PXYA 3JAKM 1UEGA 3F7PA 2R8UA 1VKAA 3HOPA 3CO1A 2WA5A 4EDMA 1SH5A 5A36A 4Q57B 2VZCA 2WFNA 1TJTA 1DXXA 1WYQA 2WA7A 1MB8A 3KMWB 2D87A 2E9KA 4TXKA 4EDNA 3JALM 4TXIA 1UJOA 1WYRA 4B7LA 2VZGB 5A38A 3FERA 2EYNA 1H67A 1WKUA 2K3SA 4EDLA 2K2RA 3KMUB 1AA2A 1WJOA 5J8EA 2D86A 3HOCA 1WIXA 2YRNA 3REPB 5A4BA 3HORA 5L0OA 1QAGA 2VZDA 1AOAA 3JARM 1WYMA 2EE7A 2D88A 1P5SA 4Q58A 2WA6A 2D89A 3I6XA 2QJXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1WYL A;  2EYI A;  2DK9 A;  1SH6 A;  2VZI B;  1PA7 A;  1WYO A;  1RT8 A;  5BVR A;  2JV9 A;  1WYP A;  1BHD A;  1BKR A;  2RR8 A;  4Q59 A;  2QJZ A;  3KY9 A;  2D85 A;  2R0O A;  5A37 A;  2L3G A;  1V5K A;  1WYN A;  1P2X A;  1PXY A;  3JAK M;  1UEG A;  3F7P A;  2R8U A;  1VKA A;  3HOP A;  3CO1 A;  2WA5 A;  4EDM A;  1SH5 A;  5A36 A;  4Q57 B;  2VZC A;  2WFN A;  1TJT A;  1DXX A;  1WYQ A;  2WA7 A;  1MB8 A;  3KMW B;  2D87 A;  2E9K A;  4TXK A;  4EDN A;  3JAL M;  4TXI A;  1UJO A;  1WYR A;  4B7L A;  2VZG B;  5A38 A;  3FER A;  2EYN A;  1H67 A;  1WKU A;  2K3S A;  4EDL A;  2K2R A;  3KMU B;  1AA2 A;  1WJO A;  5J8E A;  2D86 A;  3HOC A;  1WIX A;  2YRN A;  3REP B;  5A4B A;  3HOR A;  5L0O A;  1QAG A;  2VZD A;  1AOA A;  3JAR M;  1WYM A;  2EE7 A;  2D88 A;  1P5S A;  4Q58 A;  2WA6 A;  2D89 A;  3I6X A;  2QJX A; 
#chains in the Genus database with same CATH topology
 1WYL A;  1EUV A;  2HL8 A;  2EYI A;  2DK9 A;  1SH6 A;  2HKP A;  2VZI B;  1PA7 A;  1WYO A;  1RT8 A;  5BVR A;  2JV9 A;  1WYP A;  1BHD A;  1BKR A;  2RR8 A;  4Q59 A;  2QJZ A;  3KY9 A;  2D85 A;  2R0O A;  2WDT A;  5A37 A;  2L3G A;  3VP7 A;  1V5K A;  3EAY A;  1WYN A;  1P2X A;  1PXY A;  3JAK M;  1UEG A;  3F7P A;  2R8U A;  1VKA A;  3HOP A;  3CO1 A;  2WA5 A;  4EDM A;  1SH5 A;  2EQO A;  5A36 A;  4Q57 B;  2VZC A;  5FMU A;  2VE7 A;  4LVP A;  2WFN A;  1TJT A;  1DXX A;  1WYQ A;  2WA7 A;  1MB8 A;  3KMW B;  2D87 A;  2E9K A;  4TXK A;  5FMT A;  3JAL M;  4EDN A;  4TXI A;  1UJO A;  1WYR A;  2VE7 C;  4B7L A;  2VZG B;  5A38 A;  3FER A;  2EYN A;  4LVR A;  1H67 A;  1WKU A;  2K3S A;  4DDP A;  4EDL A;  2K2R A;  3KMU B;  1AA2 A;  2HL9 A;  1WJO A;  5J8E A;  2WE6 A;  2D86 A;  3HOC A;  1WIX A;  2YRN A;  3REP B;  5A4B A;  3HOR A;  5L0O A;  1QAG A;  2IGP A;  2VZD A;  1AOA A;  3JAR M;  1WYM A;  2EE7 A;  2D88 A;  1P5S A;  4Q58 A;  2WA6 A;  2D89 A;  3I6X A;  2QJX A; 
#chains in the Genus database with same CATH homology
 1WYL A;  2EYI A;  2DK9 A;  1SH6 A;  2VZI B;  1PA7 A;  1WYO A;  1RT8 A;  5BVR A;  2JV9 A;  1WYP A;  1BHD A;  1BKR A;  2RR8 A;  4Q59 A;  2QJZ A;  3KY9 A;  2D85 A;  2R0O A;  5A37 A;  2L3G A;  1V5K A;  1WYN A;  1P2X A;  1PXY A;  3JAK M;  1UEG A;  3F7P A;  2R8U A;  1VKA A;  3HOP A;  3CO1 A;  2WA5 A;  4EDM A;  1SH5 A;  5A36 A;  4Q57 B;  2VZC A;  2WFN A;  1TJT A;  1DXX A;  1WYQ A;  2WA7 A;  1MB8 A;  3KMW B;  2D87 A;  2E9K A;  4TXK A;  4EDN A;  3JAL M;  4TXI A;  1UJO A;  1WYR A;  4B7L A;  2VZG B;  5A38 A;  3FER A;  2EYN A;  1H67 A;  1WKU A;  2K3S A;  4EDL A;  2K2R A;  3KMU B;  1AA2 A;  1WJO A;  5J8E A;  2D86 A;  3HOC A;  1WIX A;  2YRN A;  3REP B;  5A4B A;  3HOR A;  5L0O A;  1QAG A;  2VZD A;  1AOA A;  3JAR M;  1WYM A;  2EE7 A;  2D88 A;  1P5S A;  4Q58 A;  2WA6 A;  2D89 A;  3I6X A;  2QJX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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