3FFGL

Factor xa in complex with the inhibitor (r)-6-(2'-((3- hydroxypyrrolidin-1-yl)methyl)biphenyl-4-yl)-1-(3-(5-oxo-4,5-dihydro-1h-1,2,4-triazol-3-yl)phenyl)-3-(trifluoromethyl)-5,6-dihydro-1h-pyrazolo[3,4-c]pyridin- 7(4h)-one
Total Genus 13
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
52
structure length
52
Chain Sequence
KLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Phenyltriazolinones as potent factor Xa inhibitors.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords Coagulation factor X, heavy chain
total genus 13
structure length 52
sequence length 52
ec nomenclature ec 3.4.21.6: Coagulation factor Xa.
pdb deposition date 2008-12-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF14670 FXa_inhibition Coagulation Factor Xa inhibitory site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 3ffgL00
3BT2A 1YO8A 1DDXA 1IQLL 3LC3B 1IQML 2Y5FL 2K2TA 4XL1A 3GCWE 1HX2A 2J34B 3HPTA 4PH9A 4A7IA 1HAEA 3HO3A 1FF7A 2P26A 1WU1B 1HJ7A 1CQEA 3TBDA 1KLIL 1LPGA 1B9WA 3DEMA 1KLOA 1NFUB 4LMFA 1TOZA 3KQDL 4LORA 4ZH8B 4MMZB 4YT7L 1ATDA 2FD6A 1NZIA 5L2YL 2I9AA 1WHEA 1IQEL 2XBVL 4FM5A 1NPEB 3OLTA 2BO2A 2VWLL 3QMOA 1QFKL 3QH0A 2UWPB 4BTTA 1HCGB 3KQCL 2BOUA 4BTIA 2Q1JB 3U73A 4M10A 1NFXB 3ASIA 2FZZL 1EPJA 1EGFA 1ATBA 2FLRL 1PFXL 4ISIL 3K9XA 2P3FL 3IJEB 3N8XA 4RRXA 2XBWL 1FE2A 3FCSB 3CA7A 1G1RA 1PXXA 1LMJA 4CUFA 5CKNA 1NFYB 1F7EA 2P94L 3KL6B 5I46L 3HO4A 4YZUB 4NA9L 1URKA 3KK6A 3SOBB 1HT8A 5KIRA 3TGFA 1HAFA 2P3UA 1Z6EL 1EZQB 4JZFL 3N8WA 1KIGL 2BOXA 1EPIA 5JBBE 3TZIA 4BDWA 2B7DL 2EI8B 2MHPA 1X7AL 2VJ3A 2K2SB 4O1ZA 2J94B 4MMYB 1ZAQA 4BDXA 1EMNA 5KN5C 2GD4A 4Z6AL 6COXA 3FBYA 2VVVL 3N8ZA 3LN0A 3ZYJB 5JB9E 3ZYIB 3NTGA 1EBVA 2RNLA 1F0SB 1FFMA 2RHPA 2OYUP 4XLWA 2AYLA 3OLUA 1PGEA 4Y71B 4X8VL 1J9CL 4JYVL 1EMOA 5JB8E 1V3XB 4D0FA 2FLBL 4ISHL 2Y38A 1TLEA 1LPKA 2XBYL 2WPJE 2CJIB 1N1IA 2XC5L 4Y76B 2Y81B 1GK5A 2F9BL 3IITB 3C9AC 3V65B 5IKQA 2J38B 3TK6B 1WHFA 2EI7B 4Y79B 5COXA 3Q7DA 5JBAE 2WG4B 1YGCL 4X8UL 2BOKL 2D1JB 2J2UB 4ZHAB 2PUQL 4D90A 1A3PA 2P16L 2P28B 2WPLE 5CKMA 5JVYA 2W2OE 2P93L 1P0SL 2MGPA 2FLGA 2UWLB 3RR3A 2KV4A 3SOVA 1K36A 1IQHL 2WFTA 2BMGA 2W26B 1APQA 4CSYA 3FFGL 1F7MA 3NT1A 3SOQA 1N7DA 1MQ6L 3LTFB 2BOHA 1U8CB 2BQ7A 4COXA 4C16A 1HT5A 2VVCK 5IKVA 3CFWA 1C5MF 4BTUA 4YT6L 3HO5A 2Y5GL 1L3YA 1IQFL 2KB9A 5JBCE 4RUTA 3ELAL 3LTGD 4O02B 2VWOL 4M11A 1APOA 3LN1A 5IKRA 3CENL 1IP0A 4BXSA 1G2MB 3LC5B 1IJQA 1NQLB 3P5BL 2UWOB 1EPGA 3LAQA 3N8WB 3KQBL 3V64C 3Q3KB 1CCFA 2P3TA 3ZYGA 4JYUL 3KRKA 1DIYA 1JBUL 1L5GB 2PR3B 3HS6A 4Y6DB 1EQGA 1EAIC 2XC0L 2J95B 2RA0L 2WYGB 3KCGL 1CVWL 1TPGA 2Y80B 2VH0B 1P9JA 1PTHA 1G1SA 2VWNL 1IQGL 3N8VA 4ZAEB 3MQEA 2XC4L 2WPIE 4MMXB 4ZXXL 2WPHE 4CUDA 1IQJL 1UZKA 4BXWA 1YUFA 1YUGA 2P95L 4JZEL 3KQEL 5F1AA 5JW1A 3NJPC 1HRFA 3HS7A 2YGOA 1HREA 1M1XB 2W2ME 1UZJA 1G1TA 3NTBA 4Z0LA 1YUKB 4NG9L 3LIWB 4E1GA 1Q4GA 4RRWA 2TGFA 1XDTR 2W2PE 2W2NE 3GCXE 4TGFA 5IKTA 1IGZA 2BZ6L 1FAXL 3N8YB 5FDQA 5L30L 1LPZA 3ENSA 2JKHL 4D0EA 1IOEL 5K0HB 2NPRA 1COUA 2P3FN 1KSNB 2EI6B 2WPME 1U67A 1MOXC 3EGFA 3M36L 4RRZA 3N8YA 4AQTA 3H5CB 4CUEA 1BF9A 2Y7XB 2H9EL 1Z6CA 1XKBA 1EPHA 1LQDA 4Y7BB 1AUTL 1G1QA 2WPKE 1UZQA 3TH3L 1CVUA 2VH6B 1CCVA 1ATAA 1CEJA 5L2ZL 2ADXA 2OYEP 2Y5HL 2J4IB 4X8SL 2W3IB 2VVUL 1EQHA 2WYJB 3PGHA 3BPSE 3R05A 4RS0A 3SW2A 1G2LB 1IQNL 3F6UL 1K37A 1SZBA 5EGMB 2I9BA 1DVAL 4JZDL 3HS5A 3MDLA 1IOXA 2DDUA 1O5DL 1IGXA 2G00L 4OTYA 2WFXB 4OTJA 2Y82B 4ZXYL 1F0RB 1MQ5L 1W8BL 2BQWA 4XBMA 3GISX 4G1MB 1JL9A 2M74A 1W7XL 1HZ8A 1KLJL 1UZPA 1IQKL 1FJSL 5CKQA 5E8DA 4Z0KB 1PRHA 1XKAL 5JVZA 3CS7L 3F1SB 3POYA 1NT0A 2BQ6A 4RRYA 1IVOC 5CISA 2YGPA 1FSBA 2W3KB 3BT1A 1FAKL 1XFEA 2MGRA 4X8TL 2VWMK 2W86A 4NGAL 5F19A 1DQBA 1RFNB 3TK5B 2W2QE 1ADXA 2PHBB 1ATEA 1NFWB 3QCWA 2WG3C 2Y7ZB 4Y7AB 1DX5I 3M37L 1I0UA 2XBXL 1CX2A 1OB1C 1JV2B 3U7UG 2KL7A 1IQIL
chains in the Genus database with same CATH superfamily
2H9EC 3BT2A 1YO8A 1DDXA 1IQLL 3LC3B 1IQML 2Y5FL 2K2TA 4XL1A 3GCWE 1HX2A 2J34B 3HPTA 4PH9A 4A7IA 1HAEA 3HO3A 1FF7A 2P26A 1WU1B 1HJ7A 1CQEA 3TBDA 1KLIL 1LPGA 1B9WA 1LK9A 3DEMA 1KLOA 1NFUB 4LMFA 1TOZA 3KQDL 4LORA 4ZH8B 4MMZB 4YT7L 1ATDA 2FD6A 1NZIA 2HOXA 5L2YL 2I9AA 1WHEA 1IQEL 2XBVL 4FM5A 1NPEB 3OLTA 2BO2A 2VWLL 3QMOA 1QFKL 3QH0A 2UWPB 4BTTA 1HCGB 3KQCL 2BOUA 4BTIA 2Q1JB 3U73A 4M10A 1NFXB 3ASIA 2FZZL 1EPJA 1EGFA 1ATBA 2FLRL 1PFXL 4ISIL 3K9XA 2P3FL 3IJEB 3N8XA 4RRXA 2XBWL 1FE2A 3FCSB 3CA7A 2WZPP 1G1RA 1PXXA 1LMJA 4CUFA 5CKNA 1NFYB 1F7EA 2P94L 2YGQA 3KL6B 5I46L 3HO4A 4YZUB 4NA9L 1URKA 3KK6A 3SOBB 1HT8A 5KIRA 3TGFA 1HAFA 2P3UA 1Z6EL 1EZQB 4JZFL 3N8WA 1KIGL 2BOXA 1EPIA 5JBBE 3TZIA 4BDWA 2B7DL 2EI8B 2MHPA 4GU4A 1X7AL 2VJ3A 2K2SB 4O1ZA 2J94B 2BT8A 4MMYB 1ZAQA 4BDXA 1EMNA 5KN5C 2GD4A 4Z6AL 6COXA 3FBYA 2VVVL 3N8ZA 3LN0A 3ZYJB 5JB9E 3ZYIB 3NTGA 1EBVA 2RNLA 1F0SB 1FFMA 2RHPA 2OYUP 4XLWA 2AYLA 3OLUA 2HORA 1PGEA 4Y71B 4X8VL 1J9CL 4JYVL 1LMMA 1EMOA 5JB8E 4A94C 1V3XB 2JJLA 4D0FA 2FLBL 4ISHL 2Y38A 1TLEA 1LPKA 2XBYL 2WPJE 2CJIB 1N1IA 2XC5L 4Y76B 1V1IA 1KKEA 2Y81B 1GK5A 2F9BL 3IITB 3C9AC 3V65B 5IKQA 2J38B 3TK6B 1WHFA 2EI7B 4Y79B 5COXA 3Q7DA 5JBAE 2WG4B 1YGCL 4X8UL 2BOKL 2D1JB 2J2UB 4ZHAB 2PUQL 4D90A 2VRSA 1A3PA 3S6XA 2P16L 2P28B 2WPLE 5CKMA 5JVYA 2W2OE 2P93L 1P0SL 2MGPA 2FLGA 2UWLB 3RR3A 2KV4A 3SOVA 1K36A 1IQHL 2WFTA 1V1HA 2BMGA 2W26B 1APQA 4CSYA 3FFGL 1F7MA 3NT1A 3SOQA 1N7DA 1MQ6L 3LTFB 2BOHA 1U8CB 2BQ7A 4COXA 4C16A 1HT5A 2VVCK 5IKVA 3CFWA 1C5MF 4BTUA 4YT6L 3HO5A 2Y5GL 1L3YA 1IQFL 2KB9A 5JBCE 4RUTA 3ELAL 3LTGD 4O02B 2VWOL 4M11A 4GU3A 1APOA 3LN1A 5IKRA 3CENL 1IP0A 4BXSA 1G2MB 3LC5B 1IJQA 1NQLB 3P5BL 2UWOB 1EPGA 3LAQA 3N8WB 3KQBL 3V64C 3Q3KB 1CCFA 2P3TA 3ZYGA 4JYUL 3KRKA 1DIYA 1JBUL 1L5GB 2PR3B 3HS6A 4Y6DB 1EQGA 1EAIC 2XC0L 2J95B 2RA0L 2WYGB 3KCGL 1CVWL 1TPGA 2Y80B 2VH0B 1P9JA 1PTHA 1G1SA 2VWNL 1IQGL 3N8VA 4ZAEB 3MQEA 2XC4L 2WPIE 4MMXB 4ZXXL 2WPHE 4CUDA 1IQJL 1QIUA 1UZKA 4BXWA 1YUFA 1YUGA 2P95L 4JZEL 3KQEL 5F1AA 5JW1A 3NJPC 1HRFA 3HS7A 2YGOA 1HREA 1M1XB 2W2ME 1UZJA 1G1TA 3NTBA 4Z0LA 1YUKB 4NG9L 3LIWB 4E1GA 1Q4GA 4RRWA 2TGFA 1XDTR 2W2PE 2W2NE 3GCXE 4TGFA 2BT7A 5IKTA 1IGZA 2BZ6L 1FAXL 3N8YB 5FDQA 5L30L 1LPZA 3ENSA 2BSFA 2JKHL 4D0EA 1IOEL 5K0HB 2NPRA 1COUA 2P3FN 1KSNB 2EI6B 2WPME 1U67A 1MOXC 3EGFA 3M36L 4RRZA 3N8YA 4AQTA 3H5CB 4CUEA 1BF9A 2Y7XB 2H9EL 1Z6CA 1XKBA 1EPHA 1LQDA 4Y7BB 1AUTL 1G1QA 2WPKE 1UZQA 3TH3L 1CVUA 2VH6B 1CCVA 1ATAA 1CEJA 5L2ZL 2ADXA 2OYEP 2Y5HL 2J4IB 4X8SL 2W3IB 2VVUL 1EQHA 2WYJB 3PGHA 3BPSE 3R05A 4RS0A 3SW2A 1G2LB 1IQNL 3F6UL 1K37A 1SZBA 5EGMB 2I9BA 1DVAL 4JZDL 3HS5A 3MDLA 1IOXA 2DDUA 1O5DL 1IGXA 2G00L 4OTYA 2WFXB 2KNIA 4OTJA 2Y82B 4ZXYL 1F0RB 1MQ5L 1W8BL 2BQWA 4XBMA 3GISX 4G1MB 1JL9A 2M74A 1W7XL 1HZ8A 1KLJL 1UZPA 1IQKL 1FJSL 5CKQA 5E8DA 4Z0KB 1PRHA 1XKAL 5JVZA 3CS7L 3F1SB 3POYA 1NT0A 2BQ6A 4RRYA 1IVOC 5CISA 2YGPA 1FSBA 2W3KB 3BT1A 1FAKL 1XFEA 2MGRA 4X8TL 2VWMK 2W86A 4NGAL 5F19A 1DQBA 1RFNB 3TK5B 2W2QE 1ADXA 2PHBB 1ATEA 1NFWB 3QCWA 2WG3C 2Y7ZB 4Y7AB 1DX5I 3M37L 1I0UA 2XBXL 1CX2A 1OB1C 1JV2B 3U7UG 2KL7A 1IQIL
chains in the Genus database with same CATH topology
2H9EC 3BT2A 1YO8A 1DDXA 1IQLL 3LC3B 1IQML 2Y5FL 2K2TA 4XL1A 3GCWE 1HX2A 2J34B 3HPTA 4PH9A 4A7IA 1HAEA 3HO3A 1FF7A 2P26A 1WU1B 1HJ7A 1CQEA 3TBDA 1KLIL 1LPGA 1B9WA 3DEMA 1KLOA 1NFUB 4LMFA 1TOZA 3KQDL 4LORA 4ZH8B 4MMZB 4YT7L 1ATDA 2FD6A 1NZIA 5L2YL 2I9AA 1WHEA 1IQEL 2XBVL 4FM5A 1NPEB 3OLTA 2BO2A 2VWLL 3QMOA 1QFKL 3QH0A 2UWPB 4BTTA 1HCGB 3KQCL 2BOUA 4BTIA 2Q1JB 3U73A 4M10A 1NFXB 3ASIA 2FZZL 1EPJA 1EGFA 1ATBA 2FLRL 1PFXL 4ISIL 3K9XA 2P3FL 3IJEB 3N8XA 4RRXA 2XBWL 1FE2A 3FCSB 3CA7A 2WZPP 1G1RA 1PXXA 1LMJA 4CUFA 5CKNA 1NFYB 1F7EA 2P94L 2YGQA 3KL6B 5I46L 3HO4A 4YZUB 4NA9L 1URKA 3KK6A 3SOBB 1HT8A 5KIRA 3TGFA 1HAFA 2P3UA 1Z6EL 1EZQB 4JZFL 3N8WA 1KIGL 2BOXA 1EPIA 5JBBE 3TZIA 4BDWA 2B7DL 2EI8B 2MHPA 1X7AL 2VJ3A 2K2SB 4O1ZA 2J94B 4MMYB 1ZAQA 4BDXA 1EMNA 5KN5C 2GD4A 4Z6AL 6COXA 3FBYA 2VVVL 3N8ZA 3LN0A 3ZYJB 5JB9E 3ZYIB 3NTGA 1EBVA 2RNLA 1F0SB 1FFMA 2RHPA 2OYUP 4XLWA 2AYLA 3OLUA 1PGEA 4Y71B 4X8VL 1J9CL 4JYVL 1LMMA 1EMOA 5JB8E 4A94C 1V3XB 4D0FA 2FLBL 4ISHL 2Y38A 1TLEA 1LPKA 2XBYL 2WPJE 2CJIB 1N1IA 2XC5L 4Y76B 2Y81B 1GK5A 2F9BL 3IITB 3C9AC 3V65B 5IKQA 2J38B 3TK6B 1WHFA 2EI7B 4Y79B 5COXA 3Q7DA 5JBAE 2WG4B 1YGCL 4X8UL 2BOKL 2D1JB 2J2UB 4ZHAB 2PUQL 4D90A 1A3PA 3S6XA 2P16L 2P28B 2WPLE 5CKMA 5JVYA 2W2OE 2P93L 1P0SL 2MGPA 2FLGA 2UWLB 3RR3A 2KV4A 3SOVA 1K36A 1IQHL 2WFTA 2BMGA 2W26B 1APQA 4CSYA 3FFGL 1F7MA 3NT1A 3SOQA 1N7DA 1MQ6L 3LTFB 2BOHA 1U8CB 2BQ7A 4COXA 4C16A 1HT5A 2VVCK 5IKVA 3CFWA 1C5MF 4BTUA 4YT6L 3HO5A 2Y5GL 1L3YA 1IQFL 2KB9A 5JBCE 4RUTA 3ELAL 3LTGD 4O02B 2VWOL 4M11A 1APOA 3LN1A 5IKRA 3CENL 1IP0A 4BXSA 1G2MB 3LC5B 1IJQA 1NQLB 3P5BL 2UWOB 1EPGA 3LAQA 3N8WB 3KQBL 3V64C 3Q3KB 1CCFA 2P3TA 3ZYGA 4JYUL 3KRKA 1DIYA 1JBUL 1L5GB 2PR3B 3HS6A 4Y6DB 1EQGA 1EAIC 2XC0L 2J95B 2RA0L 2WYGB 3KCGL 1CVWL 1TPGA 2Y80B 2VH0B 1P9JA 1PTHA 1G1SA 2VWNL 1IQGL 3N8VA 4ZAEB 3MQEA 2XC4L 2WPIE 4MMXB 4ZXXL 2WPHE 4CUDA 1IQJL 1UZKA 4BXWA 1YUFA 1YUGA 2P95L 4JZEL 3KQEL 5F1AA 5JW1A 3NJPC 1HRFA 3HS7A 2YGOA 1HREA 1M1XB 2W2ME 1UZJA 1G1TA 3NTBA 4Z0LA 1YUKB 4NG9L 3LIWB 4E1GA 1Q4GA 4RRWA 2TGFA 1XDTR 2W2PE 2W2NE 3GCXE 4TGFA 5IKTA 1IGZA 2BZ6L 1FAXL 3N8YB 5FDQA 5L30L 1LPZA 3ENSA 2JKHL 4D0EA 1IOEL 5K0HB 2NPRA 1COUA 2P3FN 1KSNB 2EI6B 2WPME 1U67A 1MOXC 3EGFA 3M36L 4RRZA 3N8YA 4AQTA 3H5CB 4CUEA 1BF9A 2Y7XB 2H9EL 1Z6CA 1XKBA 1EPHA 1LQDA 4Y7BB 1AUTL 1G1QA 2WPKE 1UZQA 3TH3L 1CVUA 2VH6B 1CCVA 1ATAA 1CEJA 5L2ZL 2ADXA 2OYEP 2Y5HL 2J4IB 4X8SL 2W3IB 2VVUL 1EQHA 2WYJB 3PGHA 3BPSE 3R05A 4RS0A 3SW2A 1G2LB 1IQNL 3F6UL 1K37A 1SZBA 5EGMB 2I9BA 1DVAL 4JZDL 3HS5A 3MDLA 1IOXA 2DDUA 1O5DL 1IGXA 2G00L 4OTYA 2WFXB 2KNIA 4OTJA 2Y82B 4ZXYL 1F0RB 1MQ5L 1W8BL 2BQWA 4XBMA 3GISX 4G1MB 1JL9A 2M74A 1W7XL 1HZ8A 1KLJL 1UZPA 1IQKL 1FJSL 5CKQA 5E8DA 4Z0KB 1PRHA 1XKAL 5JVZA 3CS7L 3F1SB 3POYA 1NT0A 2BQ6A 4RRYA 1IVOC 5CISA 2YGPA 1FSBA 2W3KB 3BT1A 1FAKL 1XFEA 2MGRA 4X8TL 2VWMK 2W86A 4NGAL 5F19A 1DQBA 1RFNB 3TK5B 2W2QE 1ADXA 2PHBB 1ATEA 1NFWB 3QCWA 2WG3C 2Y7ZB 4Y7AB 1DX5I 3M37L 1I0UA 2XBXL 1CX2A 1OB1C 1JV2B 3U7UG 2KL7A 1IQIL
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3BT2 A;  1YO8 A;  1DDX A;  1IQL L;  3LC3 B;  1IQM L;  2Y5F L;  2K2T A;  4XL1 A;  3GCW E;  1HX2 A;  2J34 B;  3HPT A;  4PH9 A;  4A7I A;  1HAE A;  3HO3 A;  1FF7 A;  2P26 A;  1WU1 B;  1HJ7 A;  1CQE A;  3TBD A;  1KLI L;  1LPG A;  1B9W A;  3DEM A;  1KLO A;  1NFU B;  4LMF A;  1TOZ A;  3KQD L;  4LOR A;  4ZH8 B;  4MMZ B;  4YT7 L;  1ATD A;  2FD6 A;  1NZI A;  5L2Y L;  2I9A A;  1WHE A;  1IQE L;  2XBV L;  4FM5 A;  1NPE B;  3OLT A;  2BO2 A;  2VWL L;  3QMO A;  1QFK L;  3QH0 A;  2UWP B;  4BTT A;  1HCG B;  3KQC L;  2BOU A;  4BTI A;  2Q1J B;  3U73 A;  4M10 A;  1NFX B;  3ASI A;  2FZZ L;  1EPJ A;  1EGF A;  1ATB A;  2FLR L;  1PFX L;  4ISI L;  3K9X A;  2P3F L;  3IJE B;  3N8X A;  4RRX A;  2XBW L;  1FE2 A;  3FCS B;  3CA7 A;  1G1R A;  1PXX A;  1LMJ A;  4CUF A;  5CKN A;  1NFY B;  1F7E A;  2P94 L;  3KL6 B;  5I46 L;  3HO4 A;  4YZU B;  4NA9 L;  1URK A;  3KK6 A;  3SOB B;  1HT8 A;  5KIR A;  3TGF A;  1HAF A;  2P3U A;  1Z6E L;  1EZQ B;  4JZF L;  3N8W A;  1KIG L;  2BOX A;  1EPI A;  5JBB E;  3TZI A;  4BDW A;  2B7D L;  2EI8 B;  2MHP A;  1X7A L;  2VJ3 A;  2K2S B;  4O1Z A;  2J94 B;  4MMY B;  1ZAQ A;  4BDX A;  1EMN A;  5KN5 C;  2GD4 A;  4Z6A L;  6COX A;  3FBY A;  2VVV L;  3N8Z A;  3LN0 A;  3ZYJ B;  5JB9 E;  3ZYI B;  3NTG A;  1EBV A;  2RNL A;  1F0S B;  1FFM A;  2RHP A;  2OYU P;  4XLW A;  2AYL A;  3OLU A;  1PGE A;  4Y71 B;  4X8V L;  1J9C L;  4JYV L;  1EMO A;  5JB8 E;  1V3X B;  4D0F A;  2FLB L;  4ISH L;  2Y38 A;  1TLE A;  1LPK A;  2XBY L;  2WPJ E;  2CJI B;  1N1I A;  2XC5 L;  4Y76 B;  2Y81 B;  1GK5 A;  2F9B L;  3IIT B;  3C9A C;  3V65 B;  5IKQ A;  2J38 B;  3TK6 B;  1WHF A;  2EI7 B;  4Y79 B;  5COX A;  3Q7D A;  5JBA E;  2WG4 B;  1YGC L;  4X8U L;  2BOK L;  2D1J B;  2J2U B;  4ZHA B;  2PUQ L;  4D90 A;  1A3P A;  2P16 L;  2P28 B;  2WPL E;  5CKM A;  5JVY A;  2W2O E;  2P93 L;  1P0S L;  2MGP A;  2FLG A;  2UWL B;  3RR3 A;  2KV4 A;  3SOV A;  1K36 A;  1IQH L;  2WFT A;  2BMG A;  2W26 B;  1APQ A;  4CSY A;  3FFG L;  1F7M A;  3NT1 A;  3SOQ A;  1N7D A;  1MQ6 L;  3LTF B;  2BOH A;  1U8C B;  2BQ7 A;  4COX A;  4C16 A;  1HT5 A;  2VVC K;  5IKV A;  3CFW A;  1C5M F;  4BTU A;  4YT6 L;  3HO5 A;  2Y5G L;  1L3Y A;  1IQF L;  2KB9 A;  5JBC E;  4RUT A;  3ELA L;  3LTG D;  4O02 B;  2VWO L;  4M11 A;  1APO A;  3LN1 A;  5IKR A;  3CEN L;  1IP0 A;  4BXS A;  1G2M B;  3LC5 B;  1IJQ A;  1NQL B;  3P5B L;  2UWO B;  1EPG A;  3LAQ A;  3N8W B;  3KQB L;  3V64 C;  3Q3K B;  1CCF A;  2P3T A;  3ZYG A;  4JYU L;  3KRK A;  1DIY A;  1JBU L;  1L5G B;  2PR3 B;  3HS6 A;  4Y6D B;  1EQG A;  1EAI C;  2XC0 L;  2J95 B;  2RA0 L;  2WYG B;  3KCG L;  1CVW L;  1TPG A;  2Y80 B;  2VH0 B;  1P9J A;  1PTH A;  1G1S A;  2VWN L;  1IQG L;  3N8V A;  4ZAE B;  3MQE A;  2XC4 L;  2WPI E;  4MMX B;  4ZXX L;  2WPH E;  4CUD A;  1IQJ L;  1UZK A;  4BXW A;  1YUF A;  1YUG A;  2P95 L;  4JZE L;  3KQE L;  5F1A A;  5JW1 A;  3NJP C;  1HRF A;  3HS7 A;  2YGO A;  1HRE A;  1M1X B;  2W2M E;  1UZJ A;  1G1T A;  3NTB A;  4Z0L A;  1YUK B;  4NG9 L;  3LIW B;  4E1G A;  1Q4G A;  4RRW A;  2TGF A;  1XDT R;  2W2P E;  2W2N E;  3GCX E;  4TGF A;  5IKT A;  1IGZ A;  2BZ6 L;  1FAX L;  3N8Y B;  5FDQ A;  5L30 L;  1LPZ A;  3ENS A;  2JKH L;  4D0E A;  1IOE L;  5K0H B;  2NPR A;  1COU A;  2P3F N;  1KSN B;  2EI6 B;  2WPM E;  1U67 A;  1MOX C;  3EGF A;  3M36 L;  4RRZ A;  3N8Y A;  4AQT A;  3H5C B;  4CUE A;  1BF9 A;  2Y7X B;  2H9E L;  1Z6C A;  1XKB A;  1EPH A;  1LQD A;  4Y7B B;  1AUT L;  1G1Q A;  2WPK E;  1UZQ A;  3TH3 L;  1CVU A;  2VH6 B;  1CCV A;  1ATA A;  1CEJ A;  5L2Z L;  2ADX A;  2OYE P;  2Y5H L;  2J4I B;  4X8S L;  2W3I B;  2VVU L;  1EQH A;  2WYJ B;  3PGH A;  3BPS E;  3R05 A;  4RS0 A;  3SW2 A;  1G2L B;  1IQN L;  3F6U L;  1K37 A;  1SZB A;  5EGM B;  2I9B A;  1DVA L;  4JZD L;  3HS5 A;  3MDL A;  1IOX A;  2DDU A;  1O5D L;  1IGX A;  2G00 L;  4OTY A;  2WFX B;  4OTJ A;  2Y82 B;  4ZXY L;  1F0R B;  1MQ5 L;  1W8B L;  2BQW A;  4XBM A;  3GIS X;  4G1M B;  1JL9 A;  2M74 A;  1W7X L;  1HZ8 A;  1KLJ L;  1UZP A;  1IQK L;  1FJS L;  5CKQ A;  5E8D A;  4Z0K B;  1PRH A;  1XKA L;  5JVZ A;  3CS7 L;  3F1S B;  3POY A;  1NT0 A;  2BQ6 A;  4RRY A;  1IVO C;  5CIS A;  2YGP A;  1FSB A;  2W3K B;  3BT1 A;  1FAK L;  1XFE A;  2MGR A;  4X8T L;  2VWM K;  2W86 A;  4NGA L;  5F19 A;  1DQB A;  1RFN B;  3TK5 B;  2W2Q E;  1ADX A;  2PHB B;  1ATE A;  1NFW B;  3QCW A;  2WG3 C;  2Y7Z B;  4Y7A B;  1DX5 I;  3M37 L;  1I0U A;  2XBX L;  1CX2 A;  1OB1 C;  1JV2 B;  3U7U G;  2KL7 A;  1IQI L; 
#chains in the Genus database with same CATH topology
 2H9E C;  3BT2 A;  1YO8 A;  1DDX A;  1IQL L;  3LC3 B;  1IQM L;  2Y5F L;  2K2T A;  4XL1 A;  3GCW E;  1HX2 A;  2J34 B;  3HPT A;  4PH9 A;  4A7I A;  1HAE A;  3HO3 A;  1FF7 A;  2P26 A;  1WU1 B;  1HJ7 A;  1CQE A;  3TBD A;  1KLI L;  1LPG A;  1B9W A;  1LK9 A;  3DEM A;  1KLO A;  1NFU B;  4LMF A;  1TOZ A;  3KQD L;  4LOR A;  4ZH8 B;  4MMZ B;  4YT7 L;  1ATD A;  2FD6 A;  1NZI A;  2HOX A;  5L2Y L;  2I9A A;  1WHE A;  1IQE L;  2XBV L;  4FM5 A;  1NPE B;  3OLT A;  2BO2 A;  2VWL L;  3QMO A;  1QFK L;  3QH0 A;  2UWP B;  4BTT A;  1HCG B;  3KQC L;  2BOU A;  4BTI A;  2Q1J B;  3U73 A;  4M10 A;  1NFX B;  3ASI A;  2FZZ L;  1EPJ A;  1EGF A;  1ATB A;  2FLR L;  1PFX L;  4ISI L;  3K9X A;  2P3F L;  3IJE B;  3N8X A;  4RRX A;  2XBW L;  1FE2 A;  3FCS B;  3CA7 A;  2WZP P;  1G1R A;  1PXX A;  1LMJ A;  4CUF A;  5CKN A;  1NFY B;  1F7E A;  2P94 L;  2YGQ A;  3KL6 B;  5I46 L;  3HO4 A;  4YZU B;  4NA9 L;  1URK A;  3KK6 A;  3SOB B;  1HT8 A;  5KIR A;  3TGF A;  1HAF A;  2P3U A;  1Z6E L;  1EZQ B;  4JZF L;  3N8W A;  1KIG L;  2BOX A;  1EPI A;  5JBB E;  3TZI A;  4BDW A;  2B7D L;  2EI8 B;  2MHP A;  4GU4 A;  1X7A L;  2VJ3 A;  2K2S B;  4O1Z A;  2J94 B;  2BT8 A;  4MMY B;  1ZAQ A;  4BDX A;  1EMN A;  5KN5 C;  2GD4 A;  4Z6A L;  6COX A;  3FBY A;  2VVV L;  3N8Z A;  3LN0 A;  3ZYJ B;  5JB9 E;  3ZYI B;  3NTG A;  1EBV A;  2RNL A;  1F0S B;  1FFM A;  2RHP A;  2OYU P;  4XLW A;  2AYL A;  3OLU A;  2HOR A;  1PGE A;  4Y71 B;  4X8V L;  1J9C L;  4JYV L;  1LMM A;  1EMO A;  5JB8 E;  4A94 C;  1V3X B;  2JJL A;  4D0F A;  2FLB L;  4ISH L;  2Y38 A;  1TLE A;  1LPK A;  2XBY L;  2WPJ E;  2CJI B;  1N1I A;  2XC5 L;  4Y76 B;  1V1I A;  1KKE A;  2Y81 B;  1GK5 A;  2F9B L;  3IIT B;  3C9A C;  3V65 B;  5IKQ A;  2J38 B;  3TK6 B;  1WHF A;  2EI7 B;  4Y79 B;  5COX A;  3Q7D A;  5JBA E;  2WG4 B;  1YGC L;  4X8U L;  2BOK L;  2D1J B;  2J2U B;  4ZHA B;  2PUQ L;  4D90 A;  2VRS A;  1A3P A;  3S6X A;  2P16 L;  2P28 B;  2WPL E;  5CKM A;  5JVY A;  2W2O E;  2P93 L;  1P0S L;  2MGP A;  2FLG A;  2UWL B;  3RR3 A;  2KV4 A;  3SOV A;  1K36 A;  1IQH L;  2WFT A;  1V1H A;  2BMG A;  2W26 B;  1APQ A;  4CSY A;  3FFG L;  1F7M A;  3NT1 A;  3SOQ A;  1N7D A;  1MQ6 L;  3LTF B;  2BOH A;  1U8C B;  2BQ7 A;  4COX A;  4C16 A;  1HT5 A;  2VVC K;  5IKV A;  3CFW A;  1C5M F;  4BTU A;  4YT6 L;  3HO5 A;  2Y5G L;  1L3Y A;  1IQF L;  2KB9 A;  5JBC E;  4RUT A;  3ELA L;  3LTG D;  4O02 B;  2VWO L;  4M11 A;  4GU3 A;  1APO A;  3LN1 A;  5IKR A;  3CEN L;  1IP0 A;  4BXS A;  1G2M B;  3LC5 B;  1IJQ A;  1NQL B;  3P5B L;  2UWO B;  1EPG A;  3LAQ A;  3N8W B;  3KQB L;  3V64 C;  3Q3K B;  1CCF A;  2P3T A;  3ZYG A;  4JYU L;  3KRK A;  1DIY A;  1JBU L;  1L5G B;  2PR3 B;  3HS6 A;  4Y6D B;  1EQG A;  1EAI C;  2XC0 L;  2J95 B;  2RA0 L;  2WYG B;  3KCG L;  1CVW L;  1TPG A;  2Y80 B;  2VH0 B;  1P9J A;  1PTH A;  1G1S A;  2VWN L;  1IQG L;  3N8V A;  4ZAE B;  3MQE A;  2XC4 L;  2WPI E;  4MMX B;  4ZXX L;  2WPH E;  4CUD A;  1IQJ L;  1QIU A;  1UZK A;  4BXW A;  1YUF A;  1YUG A;  2P95 L;  4JZE L;  3KQE L;  5F1A A;  5JW1 A;  3NJP C;  1HRF A;  3HS7 A;  2YGO A;  1HRE A;  1M1X B;  2W2M E;  1UZJ A;  1G1T A;  3NTB A;  4Z0L A;  1YUK B;  4NG9 L;  3LIW B;  4E1G A;  1Q4G A;  4RRW A;  2TGF A;  1XDT R;  2W2P E;  2W2N E;  3GCX E;  4TGF A;  2BT7 A;  5IKT A;  1IGZ A;  2BZ6 L;  1FAX L;  3N8Y B;  5FDQ A;  5L30 L;  1LPZ A;  3ENS A;  2BSF A;  2JKH L;  4D0E A;  1IOE L;  5K0H B;  2NPR A;  1COU A;  2P3F N;  1KSN B;  2EI6 B;  2WPM E;  1U67 A;  1MOX C;  3EGF A;  3M36 L;  4RRZ A;  3N8Y A;  4AQT A;  3H5C B;  4CUE A;  1BF9 A;  2Y7X B;  2H9E L;  1Z6C A;  1XKB A;  1EPH A;  1LQD A;  4Y7B B;  1AUT L;  1G1Q A;  2WPK E;  1UZQ A;  3TH3 L;  1CVU A;  2VH6 B;  1CCV A;  1ATA A;  1CEJ A;  5L2Z L;  2ADX A;  2OYE P;  2Y5H L;  2J4I B;  4X8S L;  2W3I B;  2VVU L;  1EQH A;  2WYJ B;  3PGH A;  3BPS E;  3R05 A;  4RS0 A;  3SW2 A;  1G2L B;  1IQN L;  3F6U L;  1K37 A;  1SZB A;  5EGM B;  2I9B A;  1DVA L;  4JZD L;  3HS5 A;  3MDL A;  1IOX A;  2DDU A;  1O5D L;  1IGX A;  2G00 L;  4OTY A;  2WFX B;  2KNI A;  4OTJ A;  2Y82 B;  4ZXY L;  1F0R B;  1MQ5 L;  1W8B L;  2BQW A;  4XBM A;  3GIS X;  4G1M B;  1JL9 A;  2M74 A;  1W7X L;  1HZ8 A;  1KLJ L;  1UZP A;  1IQK L;  1FJS L;  5CKQ A;  5E8D A;  4Z0K B;  1PRH A;  1XKA L;  5JVZ A;  3CS7 L;  3F1S B;  3POY A;  1NT0 A;  2BQ6 A;  4RRY A;  1IVO C;  5CIS A;  2YGP A;  1FSB A;  2W3K B;  3BT1 A;  1FAK L;  1XFE A;  2MGR A;  4X8T L;  2VWM K;  2W86 A;  4NGA L;  5F19 A;  1DQB A;  1RFN B;  3TK5 B;  2W2Q E;  1ADX A;  2PHB B;  1ATE A;  1NFW B;  3QCW A;  2WG3 C;  2Y7Z B;  4Y7A B;  1DX5 I;  3M37 L;  1I0U A;  2XBX L;  1CX2 A;  1OB1 C;  1JV2 B;  3U7U G;  2KL7 A;  1IQI L; 
#chains in the Genus database with same CATH homology
 2H9E C;  3BT2 A;  1YO8 A;  1DDX A;  1IQL L;  3LC3 B;  1IQM L;  2Y5F L;  2K2T A;  4XL1 A;  3GCW E;  1HX2 A;  2J34 B;  3HPT A;  4PH9 A;  4A7I A;  1HAE A;  3HO3 A;  1FF7 A;  2P26 A;  1WU1 B;  1HJ7 A;  1CQE A;  3TBD A;  1KLI L;  1LPG A;  1B9W A;  3DEM A;  1KLO A;  1NFU B;  4LMF A;  1TOZ A;  3KQD L;  4LOR A;  4ZH8 B;  4MMZ B;  4YT7 L;  1ATD A;  2FD6 A;  1NZI A;  5L2Y L;  2I9A A;  1WHE A;  1IQE L;  2XBV L;  4FM5 A;  1NPE B;  3OLT A;  2BO2 A;  2VWL L;  3QMO A;  1QFK L;  3QH0 A;  2UWP B;  4BTT A;  1HCG B;  3KQC L;  2BOU A;  4BTI A;  2Q1J B;  3U73 A;  4M10 A;  1NFX B;  3ASI A;  2FZZ L;  1EPJ A;  1EGF A;  1ATB A;  2FLR L;  1PFX L;  4ISI L;  3K9X A;  2P3F L;  3IJE B;  3N8X A;  4RRX A;  2XBW L;  1FE2 A;  3FCS B;  3CA7 A;  2WZP P;  1G1R A;  1PXX A;  1LMJ A;  4CUF A;  5CKN A;  1NFY B;  1F7E A;  2P94 L;  2YGQ A;  3KL6 B;  5I46 L;  3HO4 A;  4YZU B;  4NA9 L;  1URK A;  3KK6 A;  3SOB B;  1HT8 A;  5KIR A;  3TGF A;  1HAF A;  2P3U A;  1Z6E L;  1EZQ B;  4JZF L;  3N8W A;  1KIG L;  2BOX A;  1EPI A;  5JBB E;  3TZI A;  4BDW A;  2B7D L;  2EI8 B;  2MHP A;  1X7A L;  2VJ3 A;  2K2S B;  4O1Z A;  2J94 B;  4MMY B;  1ZAQ A;  4BDX A;  1EMN A;  5KN5 C;  2GD4 A;  4Z6A L;  6COX A;  3FBY A;  2VVV L;  3N8Z A;  3LN0 A;  3ZYJ B;  5JB9 E;  3ZYI B;  3NTG A;  1EBV A;  2RNL A;  1F0S B;  1FFM A;  2RHP A;  2OYU P;  4XLW A;  2AYL A;  3OLU A;  1PGE A;  4Y71 B;  4X8V L;  1J9C L;  4JYV L;  1LMM A;  1EMO A;  5JB8 E;  4A94 C;  1V3X B;  4D0F A;  2FLB L;  4ISH L;  2Y38 A;  1TLE A;  1LPK A;  2XBY L;  2WPJ E;  2CJI B;  1N1I A;  2XC5 L;  4Y76 B;  2Y81 B;  1GK5 A;  2F9B L;  3IIT B;  3C9A C;  3V65 B;  5IKQ A;  2J38 B;  3TK6 B;  1WHF A;  2EI7 B;  4Y79 B;  5COX A;  3Q7D A;  5JBA E;  2WG4 B;  1YGC L;  4X8U L;  2BOK L;  2D1J B;  2J2U B;  4ZHA B;  2PUQ L;  4D90 A;  1A3P A;  3S6X A;  2P16 L;  2P28 B;  2WPL E;  5CKM A;  5JVY A;  2W2O E;  2P93 L;  1P0S L;  2MGP A;  2FLG A;  2UWL B;  3RR3 A;  2KV4 A;  3SOV A;  1K36 A;  1IQH L;  2WFT A;  2BMG A;  2W26 B;  1APQ A;  4CSY A;  3FFG L;  1F7M A;  3NT1 A;  3SOQ A;  1N7D A;  1MQ6 L;  3LTF B;  2BOH A;  1U8C B;  2BQ7 A;  4COX A;  4C16 A;  1HT5 A;  2VVC K;  5IKV A;  3CFW A;  1C5M F;  4BTU A;  4YT6 L;  3HO5 A;  2Y5G L;  1L3Y A;  1IQF L;  2KB9 A;  5JBC E;  4RUT A;  3ELA L;  3LTG D;  4O02 B;  2VWO L;  4M11 A;  1APO A;  3LN1 A;  5IKR A;  3CEN L;  1IP0 A;  4BXS A;  1G2M B;  3LC5 B;  1IJQ A;  1NQL B;  3P5B L;  2UWO B;  1EPG A;  3LAQ A;  3N8W B;  3KQB L;  3V64 C;  3Q3K B;  1CCF A;  2P3T A;  3ZYG A;  4JYU L;  3KRK A;  1DIY A;  1JBU L;  1L5G B;  2PR3 B;  3HS6 A;  4Y6D B;  1EQG A;  1EAI C;  2XC0 L;  2J95 B;  2RA0 L;  2WYG B;  3KCG L;  1CVW L;  1TPG A;  2Y80 B;  2VH0 B;  1P9J A;  1PTH A;  1G1S A;  2VWN L;  1IQG L;  3N8V A;  4ZAE B;  3MQE A;  2XC4 L;  2WPI E;  4MMX B;  4ZXX L;  2WPH E;  4CUD A;  1IQJ L;  1UZK A;  4BXW A;  1YUF A;  1YUG A;  2P95 L;  4JZE L;  3KQE L;  5F1A A;  5JW1 A;  3NJP C;  1HRF A;  3HS7 A;  2YGO A;  1HRE A;  1M1X B;  2W2M E;  1UZJ A;  1G1T A;  3NTB A;  4Z0L A;  1YUK B;  4NG9 L;  3LIW B;  4E1G A;  1Q4G A;  4RRW A;  2TGF A;  1XDT R;  2W2P E;  2W2N E;  3GCX E;  4TGF A;  5IKT A;  1IGZ A;  2BZ6 L;  1FAX L;  3N8Y B;  5FDQ A;  5L30 L;  1LPZ A;  3ENS A;  2JKH L;  4D0E A;  1IOE L;  5K0H B;  2NPR A;  1COU A;  2P3F N;  1KSN B;  2EI6 B;  2WPM E;  1U67 A;  1MOX C;  3EGF A;  3M36 L;  4RRZ A;  3N8Y A;  4AQT A;  3H5C B;  4CUE A;  1BF9 A;  2Y7X B;  2H9E L;  1Z6C A;  1XKB A;  1EPH A;  1LQD A;  4Y7B B;  1AUT L;  1G1Q A;  2WPK E;  1UZQ A;  3TH3 L;  1CVU A;  2VH6 B;  1CCV A;  1ATA A;  1CEJ A;  5L2Z L;  2ADX A;  2OYE P;  2Y5H L;  2J4I B;  4X8S L;  2W3I B;  2VVU L;  1EQH A;  2WYJ B;  3PGH A;  3BPS E;  3R05 A;  4RS0 A;  3SW2 A;  1G2L B;  1IQN L;  3F6U L;  1K37 A;  1SZB A;  5EGM B;  2I9B A;  1DVA L;  4JZD L;  3HS5 A;  3MDL A;  1IOX A;  2DDU A;  1O5D L;  1IGX A;  2G00 L;  4OTY A;  2WFX B;  2KNI A;  4OTJ A;  2Y82 B;  4ZXY L;  1F0R B;  1MQ5 L;  1W8B L;  2BQW A;  4XBM A;  3GIS X;  4G1M B;  1JL9 A;  2M74 A;  1W7X L;  1HZ8 A;  1KLJ L;  1UZP A;  1IQK L;  1FJS L;  5CKQ A;  5E8D A;  4Z0K B;  1PRH A;  1XKA L;  5JVZ A;  3CS7 L;  3F1S B;  3POY A;  1NT0 A;  2BQ6 A;  4RRY A;  1IVO C;  5CIS A;  2YGP A;  1FSB A;  2W3K B;  3BT1 A;  1FAK L;  1XFE A;  2MGR A;  4X8T L;  2VWM K;  2W86 A;  4NGA L;  5F19 A;  1DQB A;  1RFN B;  3TK5 B;  2W2Q E;  1ADX A;  2PHB B;  1ATE A;  1NFW B;  3QCW A;  2WG3 C;  2Y7Z B;  4Y7A B;  1DX5 I;  3M37 L;  1I0U A;  2XBX L;  1CX2 A;  1OB1 C;  1JV2 B;  3U7U G;  2KL7 A;  1IQI L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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