3FHHA

Crystal structure of the heme/hemoglobin outer membrane transporter shua from shigella dysenteriae
Total Genus 163
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
163
sequence length
640
structure length
621
Chain Sequence
TETMTVTATGNARSSFEAPMMVSVIDTSAPENQTATSATDLLRHVPGITLDGTGRTNGQDINMRGYDHRGVLVLVDGIRQGTDTGHLNGTFLDPALIKRVEIVRGPSALLYGSGALGGVISYDTVDAKDLLQEGQSSGFRVFGTGGTGDHSLGLGASAFGRTENLDGIVAWSSRDRGDLRQSNGETAPNDESINNMLAKGTWQIDSAQSLSGLVRYYNNDAREPKNPQTVEASESSNPMVDRSTIQRDAQLSYKLAPQGNDWLNADAKIYWSEVRINAQEYREQITKGARLENRSTLFADSFASHLLTYGGEYYRQEQGSHTTGFPQAKIDFSSGWLQDEITLRDLPITLLGGTRYDSYRGSSDGYKDVDADKWSSRAGMTINPTNWLMLFGSYAQAFRAPTMGEMYNDSKHFSIGRFYTNYWVPNPNLRPETNETQEYGFGLRFDDLMLSNDALEFKASYFDTKAKDYISTTVDFAAATTMSYNVPNAKIWGWDVMTKYTTDLFSLDVAYNRTRGKDTDTGEYISSINPDTVTSTLNIPIAHSGFSVGWVGTFADRSTHISSKQPGYGVNDFYVSYQGQQALKGMTTTLVLGNAFDKEYWSPQGIPQDGRNGKIFVSYQW
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure of the heme/hemoglobin outer membrane transporter ShuA from the human pathogen /Shigella dysenteriae /bound to divalent cations: heme binding by an extracellular induced fit mechanism
rcsb
molecule tags Membrane protein
source organism Shigella dysenteriae
molecule keywords Outer membrane heme receptor ShuA
total genus 163
structure length 621
sequence length 640
ec nomenclature
pdb deposition date 2008-12-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00593 TonB_dep_Rec TonB dependent receptor
A PF07715 Plug TonB-dependent Receptor Plug Domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.170.20 Mainly Beta Beta Barrel Maltoporin; Chain A TonB-dependent receptor, beta-barrel domain 3fhhA02
2.170.130.10 Mainly Beta Beta Complex Ferric Hydroxamate Uptake Protein; Chain A, domain 1 TonB-dependent receptor, plug domain 3fhhA01
2W76A 2W6UA 3CSNA 4RDRA 1FCPA 4AIQA 3RGMA 1NQGA 1KMPA 1QFGA 3M8DA 1PO0A 1XKHA 5FOKA 1QJQA 1XKWA 2GRXA 2GSKA 1QFFA 3CSLA 1UJWA 2O5PA 1NQHA 2FCPA 1FEPA 4B7OA 1KMOA 4AIPA 2W78A 1NQFA 3QLBA 1PNZA 1BY5A 2W77A 2YSUA 3V8XA 3FHHA 3V89A 3DDRA 2HDFA 3EFMA 4RDTA 4CU4A 1PO3A 1QKCA 3RGNA 1NQEA 2IAHA 2W6TA 2GUFA 2W75A 1BY3A 3M8BA 4EPAA 1FI1A 2HDIA 2W16A
chains in the Genus database with same CATH superfamily
2W76A 2W6UA 3CSNA 4RDRA 1FCPA 1A0TP 3RGMA 1MPOA 4AIQA 1NQGA 1KMPA 1QFGA 3M8DA 1PO0A 1XKHA 5FOKA 1QJQA 1XKWA 2GRXA 2GSKA 1QFFA 3CSLA 1UJWA 2O5PA 1NQHA 2FCPA 2MPRA 1JBIA 1FEPA 4B7OA 1KMOA 4AIPA 1MPRA 1AF6A 2W78A 1MPNA 1OH2P 1A0SP 1NQFA 3QLBA 1PNZA 1BY5A 1MPMA 1OH2Q 2W77A 2YSUA 3V8XA 3FHHA 3V89A 3DDRA 2HDFA 3EFMA 4RDTA 4CU4A 1PO3A 1QKCA 3RGNA 1NQEA 2IAHA 1MPQA 2GUFA 2W6TA 2W75A 1BY3A 3M8BA 2HDIA 4EPAA 1FI1A 1MALA 2W16A
chains in the Genus database with same CATH topology
2W76A 2W6UA 3CSNA 4RDRA 1FCPA 4AIQA 3RGMA 1NQGA 1KMPA 1QFGA 3M8DA 1PO0A 1XKHA 5FOKA 1QJQA 1XKWA 2GRXA 2GSKA 1QFFA 3CSLA 1UJWA 2O5PA 1NQHA 2FCPA 1FEPA 4B7OA 1KMOA 4AIPA 2W78A 1NQFA 3QLBA 1PNZA 1BY5A 2W77A 2YSUA 3V8XA 3FHHA 3V89A 3DDRA 2HDFA 3EFMA 4RDTA 4CU4A 1PO3A 1QKCA 3RGNA 1NQEA 2IAHA 2W6TA 2GUFA 2W75A 1BY3A 3M8BA 4EPAA 1FI1A 2HDIA 2W16A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2W76 A;  2W6U A;  3CSN A;  4RDR A;  1FCP A;  4AIQ A;  3RGM A;  1NQG A;  1KMP A;  1QFG A;  3M8D A;  1PO0 A;  1XKH A;  5FOK A;  1QJQ A;  1XKW A;  2GRX A;  2GSK A;  1QFF A;  3CSL A;  1UJW A;  2O5P A;  1NQH A;  2FCP A;  1FEP A;  4B7O A;  1KMO A;  4AIP A;  2W78 A;  1NQF A;  3QLB A;  1PNZ A;  1BY5 A;  2W77 A;  2YSU A;  3V8X A;  3FHH A;  3V89 A;  3DDR A;  2HDF A;  3EFM A;  4RDT A;  4CU4 A;  1PO3 A;  1QKC A;  3RGN A;  1NQE A;  2IAH A;  2W6T A;  2GUF A;  2W75 A;  1BY3 A;  3M8B A;  4EPA A;  1FI1 A;  2HDI A;  2W16 A; 
#chains in the Genus database with same CATH topology
 2W76 A;  2W6U A;  3CSN A;  4RDR A;  1FCP A;  1A0T P;  3RGM A;  1MPO A;  4AIQ A;  1NQG A;  1KMP A;  1QFG A;  3M8D A;  1PO0 A;  1XKH A;  5FOK A;  1QJQ A;  1XKW A;  2GRX A;  2GSK A;  1QFF A;  3CSL A;  1UJW A;  2O5P A;  1NQH A;  2FCP A;  2MPR A;  1JBI A;  1FEP A;  4B7O A;  1KMO A;  4AIP A;  1MPR A;  1AF6 A;  2W78 A;  1MPN A;  1OH2 P;  1A0S P;  1NQF A;  3QLB A;  1PNZ A;  1BY5 A;  1MPM A;  1OH2 Q;  2W77 A;  2YSU A;  3V8X A;  3FHH A;  3V89 A;  3DDR A;  2HDF A;  3EFM A;  4RDT A;  4CU4 A;  1PO3 A;  1QKC A;  3RGN A;  1NQE A;  2IAH A;  1MPQ A;  2GUF A;  2W6T A;  2W75 A;  1BY3 A;  3M8B A;  2HDI A;  4EPA A;  1FI1 A;  1MAL A;  2W16 A; 
#chains in the Genus database with same CATH homology
 2W76 A;  2W6U A;  3CSN A;  4RDR A;  1FCP A;  4AIQ A;  3RGM A;  1NQG A;  1KMP A;  1QFG A;  3M8D A;  1PO0 A;  1XKH A;  5FOK A;  1QJQ A;  1XKW A;  2GRX A;  2GSK A;  1QFF A;  3CSL A;  1UJW A;  2O5P A;  1NQH A;  2FCP A;  1FEP A;  4B7O A;  1KMO A;  4AIP A;  2W78 A;  1NQF A;  3QLB A;  1PNZ A;  1BY5 A;  2W77 A;  2YSU A;  3V8X A;  3FHH A;  3V89 A;  3DDR A;  2HDF A;  3EFM A;  4RDT A;  4CU4 A;  1PO3 A;  1QKC A;  3RGN A;  1NQE A;  2IAH A;  2W6T A;  2GUF A;  2W75 A;  1BY3 A;  3M8B A;  4EPA A;  1FI1 A;  2HDI A;  2W16 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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