3FW8A

Structure of berberine bridge enzyme, c166a variant
Total Genus 169
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
169
sequence length
495
structure length
495
Chain Sequence
DLLSCLTFNGVRNHTVFSADSDSDFNRFLHLSIQNPLFQNSLISKPSAIILPGSKEELSNTIRCIRKGSWTIRLRSGGHSYEGLSYTSDTPFILIDLMNLNRVSIDLESETAWVESGSTLGELYYAITESSSKLGFTAGWAPTVGTGGHISGGGFGMMSRKYGLAADNVVDAILIDANGAILDRQAMGEDVFWAIRGGGGGVWGAIYAWKIKLLPVPEKVTVFRVTKNVAIDEATSLLHKWQFVAEELEEDFTLSVLGGADEKQVWLTMLGFHFGLKTVAKSTFDLLFPELGLVEEDYLEMSWGESFAYLAGLETVSQLNNRFLKFDERAFKTKVDLTKEPLPSKAFYGLLERLSKEPNGFIALNGFGGQMSKISSDFTPFPHRSGTRLMVEYIVAWNQSEQKKKTEFLDWLEKVYEFMKPFVSKNPRLGYVNHIDLDLGGIDWGNKTVVNNAIEISRSWGESYFLSNYERLIRAKTLIDPNNVFNHPQSIPPMA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Reticuline oxidase
publication title Structural roles of biocovalent flaninylation in berberine bridge enzyme
rcsb
source organism Eschscholzia californica
molecule tags Flavoprotein
total genus 169
structure length 495
sequence length 495
ec nomenclature ec 1.21.3.3: Reticuline oxidase.
pdb deposition date 2009-01-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF08031 BBE Berberine and berberine like
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 3fw8A01
3.30.465.50 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 3fw8A02
3.40.462.20 Alpha Beta 3-Layer(aba) Sandwich Vanillyl-alcohol Oxidase; Chain A, domain 3 Vanillyl-alcohol Oxidase; Chain A, domain 3 3fw8A03
2VFUA 2BVHA 3FW9A 3W8ZA 5I1VA 4BC7A 3TSHA 1AHVA 1UXYA 2QPMA 2Y08A 1W1JA 3NRZB 3ETRB 5AE3A 5L6FA 1FFVC 3S1DA 1N61C 1ZXIC 3RJAA 3RJ8A 3PQBA 5FXEA 1N63C 3GSYA 1MBTA 1I19A 4ML8A 5HHZA 1JROA 2GQTA 2VFTA 3NS1B 3S1FA 1E8FA 2VFRA 3KJMA 2W3RA 2AXRA 3BW7A 1N62C 2MBRA 1WVEA 2Q85A 4UD8A 5HQXA 2Y3RA 3FW7A 1FO4A 1W1LA 3FW8A 3TX1A 1E8HA 2EXRA 3W8XA 1W1KA 4PVHA 4MLAA 1DIIA 2I0KA 5AE1A 1DZNA 5AWVA 4JAYA 3B9JB 1V97A 2GQUA 5L6GA 4DNSA 3NVZB 1ZR6A 1AHZA 2E3TA 4EC3A 4O95A 4BCAA 2IPIA 1QLUA 2BVFA 2W3SA 1N5XA 3D2DA 1MBBA 1E0YA 5AE2A 1N60C 3D2JA 1QLTA 1W1SA 2QKNA 2Q4WA 2Y3SA 4JB1A 3D2HA 1FIQB 1WYGA 3FWAA 1T3QC 1W1QA 3JS8A 3EUB3 3I99A 3SR6B 4XLOA 3TSJA 4PVJA 5FXFA 4PVKA 1W1RA 1VDVA 3AM9A 5K8EA 5HMRA 4PYTA 2VFSA 2VFVA 5ADZA 1N5WC 3POPA 2VAOA 3PM9A 1AHUA 3C0PA 4PVEA 3AMZA 1F0XA 3HSUA 3AN1A 2Y4GA 4BBYA 5D79A 4ZOHB 5FXDA 1DIQA 2W54A 1E8GA 1W1MA 3S1CA 1W1OA 4PZFA 2WDWA 5FXPA 2BVGA 1HSKA 1WVFA 3DQ0A 3S1EA 3VTEA 3W8WA 4OALA 4BC9A 1VAOA 2W55A 4PWBA 4PWCA 5I1WA 1FFUC
chains in the Genus database with same CATH superfamily
2VFUA 2BVHA 2OAIA 3FW9A 3W8ZA 5I1VA 4BC7A 3TSHA 1AHVA 5G5GB 1UXYA 2QPMA 2Y08A 1W1JA 3NRZB 3ETRB 5AE3A 4HG0A 5L6FA 1FFVC 3S1DA 1N61C 1ZXIC 3RJAA 3RJ8A 3PQBA 5FXEA 1N63C 3GSYA 2RK5A 1MBTA 1I19A 4ML8A 5HHZA 1JROA 3NVWB 2P4PA 2GQTA 2VFTA 1SB3B 3NS1B 3S1FA 3HRDC 1E8FA 3LLBA 2UUVA 2VFRA 3KJMA 2W3RA 2AXRA 3BW7A 1N62C 2MBRA 1WVEA 2Q85A 4UD8A 2YVSA 5HQXA 2Y3RA 3FW7A 3EJEB 1RM6B 3DEDA 1FO4A 3NVVB 1W1LA 3FW8A 3TX1A 1E8HA 2EXRA 3W8XA 5G5HB 1W1KA 2PLIA 4PVHA 4MLAA 1DIIA 2I0KA 5AE1A 1DZNA 5AWVA 4JAYA 3B9JB 1V97A 2GQUA 5L6GA 4DNSA 3NVZB 1ZR6A 1AHZA 2E3TA 4EC3A 4O95A 4BCAA 2IPIA 2R2ZA 1QLUA 3NVYB 2BVFA 2W3SA 1N5XA 3D2DA 1MBBA 1E0YA 5AE2A 1N60C 3D2JA 2R8DA 1QLTA 1W1SA 2QKNA 2Q4WA 2Y3SA 4JB1A 3D2HA 1FIQB 2P13A 1WYGA 3FWAA 1T3QC 1W1QA 3JS8A 3EUB3 2UUUA 3I99A 3SR6B 4XLOA 3TSJA 4PVJA 5FXFA 4PVKA 1W1RA 2NQWA 1VDVA 3AM9A 5K8EA 5HMRA 3EJBB 2VFSA 4PYTA 2VFVA 5ADZA 1N5WC 2P3HA 3POPA 2VAOA 3PM9A 3LAEA 3EJDB 1AHUA 3C0PA 2O3GA 4PVEA 3AMZA 1F0XA 3HSUA 3AN1A 2Y4GA 4BBYA 5D79A 4ZOHB 2PLSA 5FXDA 1DIQA 2W54A 1E8GA 1W1MA 3S1CA 1W1OA 4PZFA 2WDWA 1JRPA 5FXPA 2BVGA 1HSKA 1WVFA 3DQ0A 3S1EA 3VTEA 3W8WA 4OALA 4BC9A 1VAOA 2W55A 4PWBA 4PWCA 5I1WA 1FFUC
chains in the Genus database with same CATH topology
2VFUA 2BVHA 2OAIA 3FW9A 3W8ZA 5I1VA 4BC7A 3TSHA 1AHVA 5G5GB 1UXYA 2QPMA 2Y08A 1W1JA 3NRZB 3ETRB 5AE3A 4HG0A 5L6FA 1FFVC 3S1DA 1N61C 1ZXIC 3RJAA 3RJ8A 3PQBA 5FXEA 1N63C 3GSYA 2RK5A 1MBTA 1I19A 4ML8A 5HHZA 1JROA 2P4PA 3NVWB 2GQTA 2VFTA 1SB3B 3NS1B 3S1FA 3HRDC 1E8FA 3LLBA 2UUVA 2VFRA 3KJMA 2W3RA 2AXRA 3BW7A 1N62C 2MBRA 1WVEA 2Q85A 4UD8A 2YVSA 5HQXA 2Y3RA 3FW7A 1RM6B 3DEDA 1FO4A 3NVVB 1W1LA 3FW8A 3TX1A 1E8HA 2EXRA 3W8XA 5G5HB 1W1KA 2PLIA 4PVHA 4MLAA 1DIIA 2I0KA 5AE1A 1DZNA 5AWVA 4JAYA 3B9JB 1V97A 2GQUA 5L6GA 4DNSA 3NVZB 1ZR6A 1AHZA 2E3TA 4EC3A 4O95A 4BCAA 2IPIA 2R2ZA 1QLUA 3NVYB 2BVFA 2W3SA 1N5XA 3D2DA 1MBBA 1E0YA 5AE2A 1N60C 3D2JA 2R8DA 1QLTA 1W1SA 2QKNA 2Q4WA 2Y3SA 4JB1A 3D2HA 1FIQB 2P13A 1WYGA 3FWAA 1T3QC 1W1QA 3JS8A 3EUB3 2UUUA 3I99A 3SR6B 4XLOA 3TSJA 4PVJA 5FXFA 4PVKA 1W1RA 2NQWA 1VDVA 3AM9A 5K8EA 5HMRA 4PYTA 2VFSA 2VFVA 5ADZA 1N5WC 2P3HA 3POPA 2VAOA 3PM9A 3LAEA 1AHUA 3C0PA 2O3GA 4PVEA 3AMZA 1F0XA 3HSUA 3AN1A 2Y4GA 4BBYA 5D79A 4ZOHB 2PLSA 5FXDA 1DIQA 2W54A 1E8GA 1W1MA 3S1CA 1W1OA 4PZFA 2WDWA 1JRPA 5FXPA 2BVGA 1HSKA 1WVFA 3DQ0A 3S1EA 3VTEA 3W8WA 4OALA 4BC9A 1VAOA 2W55A 4PWBA 4PWCA 5I1WA 1FFUC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2VFU A;  2BVH A;  3FW9 A;  3W8Z A;  5I1V A;  4BC7 A;  3TSH A;  1AHV A;  1UXY A;  2QPM A;  2Y08 A;  1W1J A;  3NRZ B;  3ETR B;  5AE3 A;  5L6F A;  1FFV C;  3S1D A;  1N61 C;  1ZXI C;  3RJA A;  3RJ8 A;  3PQB A;  5FXE A;  1N63 C;  3GSY A;  1MBT A;  1I19 A;  4ML8 A;  5HHZ A;  1JRO A;  2GQT A;  2VFT A;  3NS1 B;  3S1F A;  1E8F A;  2VFR A;  3KJM A;  2W3R A;  2AXR A;  3BW7 A;  1N62 C;  2MBR A;  1WVE A;  2Q85 A;  4UD8 A;  5HQX A;  2Y3R A;  3FW7 A;  1FO4 A;  1W1L A;  3FW8 A;  3TX1 A;  1E8H A;  2EXR A;  3W8X A;  1W1K A;  4PVH A;  4MLA A;  1DII A;  2I0K A;  5AE1 A;  1DZN A;  5AWV A;  4JAY A;  3B9J B;  1V97 A;  2GQU A;  5L6G A;  4DNS A;  3NVZ B;  1ZR6 A;  1AHZ A;  2E3T A;  4EC3 A;  4O95 A;  4BCA A;  2IPI A;  1QLU A;  2BVF A;  2W3S A;  1N5X A;  3D2D A;  1MBB A;  1E0Y A;  5AE2 A;  1N60 C;  3D2J A;  1QLT A;  1W1S A;  2QKN A;  2Q4W A;  2Y3S A;  4JB1 A;  3D2H A;  1FIQ B;  1WYG A;  3FWA A;  1T3Q C;  1W1Q A;  3JS8 A;  3EUB 3;  3I99 A;  3SR6 B;  4XLO A;  3TSJ A;  4PVJ A;  5FXF A;  4PVK A;  1W1R A;  1VDV A;  3AM9 A;  5K8E A;  5HMR A;  4PYT A;  2VFS A;  2VFV A;  5ADZ A;  1N5W C;  3POP A;  2VAO A;  3PM9 A;  1AHU A;  3C0P A;  4PVE A;  3AMZ A;  1F0X A;  3HSU A;  3AN1 A;  2Y4G A;  4BBY A;  5D79 A;  4ZOH B;  5FXD A;  1DIQ A;  2W54 A;  1E8G A;  1W1M A;  3S1C A;  1W1O A;  4PZF A;  2WDW A;  5FXP A;  2BVG A;  1HSK A;  1WVF A;  3DQ0 A;  3S1E A;  3VTE A;  3W8W A;  4OAL A;  4BC9 A;  1VAO A;  2W55 A;  4PWB A;  4PWC A;  5I1W A;  1FFU C; 
#chains in the Genus database with same CATH topology
 2VFU A;  2BVH A;  2OAI A;  3FW9 A;  3W8Z A;  5I1V A;  4BC7 A;  3TSH A;  1AHV A;  5G5G B;  1UXY A;  2QPM A;  2Y08 A;  1W1J A;  3NRZ B;  3ETR B;  5AE3 A;  4HG0 A;  5L6F A;  1FFV C;  3S1D A;  1N61 C;  1ZXI C;  3RJA A;  3RJ8 A;  3PQB A;  5FXE A;  1N63 C;  3GSY A;  2RK5 A;  1MBT A;  1I19 A;  4ML8 A;  5HHZ A;  1JRO A;  3NVW B;  2P4P A;  2GQT A;  2VFT A;  1SB3 B;  3NS1 B;  3S1F A;  3HRD C;  1E8F A;  3LLB A;  2UUV A;  2VFR A;  3KJM A;  2W3R A;  2AXR A;  3BW7 A;  1N62 C;  2MBR A;  1WVE A;  2Q85 A;  4UD8 A;  2YVS A;  5HQX A;  2Y3R A;  3FW7 A;  3EJE B;  1RM6 B;  3DED A;  1FO4 A;  3NVV B;  1W1L A;  3FW8 A;  3TX1 A;  1E8H A;  2EXR A;  3W8X A;  5G5H B;  1W1K A;  2PLI A;  4PVH A;  4MLA A;  1DII A;  2I0K A;  5AE1 A;  1DZN A;  5AWV A;  4JAY A;  3B9J B;  1V97 A;  2GQU A;  5L6G A;  4DNS A;  3NVZ B;  1ZR6 A;  1AHZ A;  2E3T A;  4EC3 A;  4O95 A;  4BCA A;  2IPI A;  2R2Z A;  1QLU A;  3NVY B;  2BVF A;  2W3S A;  1N5X A;  3D2D A;  1MBB A;  1E0Y A;  5AE2 A;  1N60 C;  3D2J A;  2R8D A;  1QLT A;  1W1S A;  2QKN A;  2Q4W A;  2Y3S A;  4JB1 A;  3D2H A;  1FIQ B;  2P13 A;  1WYG A;  3FWA A;  1T3Q C;  1W1Q A;  3JS8 A;  3EUB 3;  2UUU A;  3I99 A;  3SR6 B;  4XLO A;  3TSJ A;  4PVJ A;  5FXF A;  4PVK A;  1W1R A;  2NQW A;  1VDV A;  3AM9 A;  5K8E A;  5HMR A;  3EJB B;  2VFS A;  4PYT A;  2VFV A;  5ADZ A;  1N5W C;  2P3H A;  3POP A;  2VAO A;  3PM9 A;  3LAE A;  3EJD B;  1AHU A;  3C0P A;  2O3G A;  4PVE A;  3AMZ A;  1F0X A;  3HSU A;  3AN1 A;  2Y4G A;  4BBY A;  5D79 A;  4ZOH B;  2PLS A;  5FXD A;  1DIQ A;  2W54 A;  1E8G A;  1W1M A;  3S1C A;  1W1O A;  4PZF A;  2WDW A;  1JRP A;  5FXP A;  2BVG A;  1HSK A;  1WVF A;  3DQ0 A;  3S1E A;  3VTE A;  3W8W A;  4OAL A;  4BC9 A;  1VAO A;  2W55 A;  4PWB A;  4PWC A;  5I1W A;  1FFU C; 
#chains in the Genus database with same CATH homology
 2VFU A;  2BVH A;  2OAI A;  3FW9 A;  3W8Z A;  5I1V A;  4BC7 A;  3TSH A;  1AHV A;  5G5G B;  1UXY A;  2QPM A;  2Y08 A;  1W1J A;  3NRZ B;  3ETR B;  5AE3 A;  4HG0 A;  5L6F A;  1FFV C;  3S1D A;  1N61 C;  1ZXI C;  3RJA A;  3RJ8 A;  3PQB A;  5FXE A;  1N63 C;  3GSY A;  2RK5 A;  1MBT A;  1I19 A;  4ML8 A;  5HHZ A;  1JRO A;  2P4P A;  3NVW B;  2GQT A;  2VFT A;  1SB3 B;  3NS1 B;  3S1F A;  3HRD C;  1E8F A;  3LLB A;  2UUV A;  2VFR A;  3KJM A;  2W3R A;  2AXR A;  3BW7 A;  1N62 C;  2MBR A;  1WVE A;  2Q85 A;  4UD8 A;  2YVS A;  5HQX A;  2Y3R A;  3FW7 A;  1RM6 B;  3DED A;  1FO4 A;  3NVV B;  1W1L A;  3FW8 A;  3TX1 A;  1E8H A;  2EXR A;  3W8X A;  5G5H B;  1W1K A;  2PLI A;  4PVH A;  4MLA A;  1DII A;  2I0K A;  5AE1 A;  1DZN A;  5AWV A;  4JAY A;  3B9J B;  1V97 A;  2GQU A;  5L6G A;  4DNS A;  3NVZ B;  1ZR6 A;  1AHZ A;  2E3T A;  4EC3 A;  4O95 A;  4BCA A;  2IPI A;  2R2Z A;  1QLU A;  3NVY B;  2BVF A;  2W3S A;  1N5X A;  3D2D A;  1MBB A;  1E0Y A;  5AE2 A;  1N60 C;  3D2J A;  2R8D A;  1QLT A;  1W1S A;  2QKN A;  2Q4W A;  2Y3S A;  4JB1 A;  3D2H A;  1FIQ B;  2P13 A;  1WYG A;  3FWA A;  1T3Q C;  1W1Q A;  3JS8 A;  3EUB 3;  2UUU A;  3I99 A;  3SR6 B;  4XLO A;  3TSJ A;  4PVJ A;  5FXF A;  4PVK A;  1W1R A;  2NQW A;  1VDV A;  3AM9 A;  5K8E A;  5HMR A;  4PYT A;  2VFS A;  2VFV A;  5ADZ A;  1N5W C;  2P3H A;  3POP A;  2VAO A;  3PM9 A;  3LAE A;  1AHU A;  3C0P A;  2O3G A;  4PVE A;  3AMZ A;  1F0X A;  3HSU A;  3AN1 A;  2Y4G A;  4BBY A;  5D79 A;  4ZOH B;  2PLS A;  5FXD A;  1DIQ A;  2W54 A;  1E8G A;  1W1M A;  3S1C A;  1W1O A;  4PZF A;  2WDW A;  1JRP A;  5FXP A;  2BVG A;  1HSK A;  1WVF A;  3DQ0 A;  3S1E A;  3VTE A;  3W8W A;  4OAL A;  4BC9 A;  1VAO A;  2W55 A;  4PWB A;  4PWC A;  5I1W A;  1FFU C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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