3FWAA

Structure of berberine bridge enzyme, c166a variant in complex with (s)-reticuline
Total Genus 169
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
169
sequence length
497
structure length
497
Chain Sequence
DLLSCLTFNGVRNHTVFSADSDSDFNRFLHLSIQNPLFQNSLISKPSAIILPGSKEELSNTIRCIRKGSWTIRLRSGGHSYEGLSYTSDTPFILIDLMNLNRVSIDLESETAWVESGSTLGELYYAITESSSKLGFTAGWAPTVGTGGHISGGGFGMMSRKYGLAADNVVDAILIDANGAILDRQAMGEDVFWAIRGGGGGVWGAIYAWKIKLLPVPEKVTVFRVTKNVAIDEATSLLHKWQFVAEELEEDFTLSVLGGADEKQVWLTMLGFHFGLKTVAKSTFDLLFPELGLVEEDYLEMSWGESFAYLAGLETVSQLNNRFLKFDERAFKTKVDLTKEPLPSKAFYGLLERLSKEPNGFIALNGFGGQMSKISSDFTPFPHRSGTRLMVEYIVAWNQSEQKKKTEFLDWLEKVYEFMKPFVSKNPRLGYVNHIDLDLGGIDWGNKTVVNNAIEISRSWGESYFLSNYERLIRAKTLIDPNNVFNHPQSIPPMANF
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural roles of biocovalent flaninylation in berberine bridge enzyme
rcsb
source organism Eschscholzia californica
molecule tags Flavoprotein
molecule keywords Reticuline oxidase
total genus 169
structure length 497
sequence length 497
ec nomenclature ec 1.21.3.3: Reticuline oxidase.
pdb deposition date 2009-01-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF08031 BBE Berberine and berberine like
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 3fwaA01
3.30.465.50 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 3fwaA02
3.40.462.20 Alpha Beta 3-Layer(aba) Sandwich Vanillyl-alcohol Oxidase; Chain A, domain 3 Vanillyl-alcohol Oxidase; Chain A, domain 3 3fwaA03
1QLUA 4DNSA 5HHZA 1F0XA 1AHVA 5AE1A 3FWAA 1N5WC 4PZFA 3PQBA 1WYGA 2VFTA 1W1OA 3AMZA 3NRZB 2W3SA 5L6FA 3RJAA 2BVGA 1W1KA 2WDWA 2Y3SA 1ZXIC 3VTEA 1W1JA 5AWVA 4XLOA 4JAYA 1W1QA 4UD8A 3D2DA 2VFSA 2Y4GA 1AHUA 4PYTA 1WVFA 1N63C 3PM9A 3S1EA 3W8XA 1FFVC 1N5XA 1W1LA 3TSJA 2MBRA 5AE2A 1FO4A 1VDVA 3NS1B 3TX1A 5FXFA 5HMRA 2W54A 3RJ8A 5AE3A 3SR6B 3HSUA 3AN1A 2Q85A 2Y3RA 1E8FA 5I1VA 1WVEA 1DIQA 1W1SA 4ML8A 2E3TA 2QKNA 1QLTA 3DQ0A 1I19A 4PVEA 3BW7A 1FIQB 4PVHA 3FW8A 3FW9A 1W1RA 3W8WA 3KJMA 1AHZA 3W8ZA 3EUB3 3GSYA 2Y08A 2IPIA 3S1CA 3ETRB 1E8HA 1N62C 2VFRA 4BCAA 5K8EA 1N60C 2W55A 2VFUA 2W3RA 1DZNA 3S1FA 3D2JA 1MBBA 3C0PA 1JROA 2GQTA 1MBTA 3B9JB 5ADZA 3AM9A 2VAOA 5L6GA 1E0YA 2EXRA 2VFVA 5FXPA 2QPMA 1T3QC 5FXDA 5I1WA 1W1MA 1DIIA 4EC3A 3D2HA 4O95A 2BVHA 4PWBA 5D79A 3NVZB 4PVJA 3JS8A 3TSHA 1UXYA 4ZOHB 3POPA 1FFUC 1E8GA 2AXRA 5HQXA 4MLAA 4PWCA 2BVFA 3FW7A 4PVKA 1VAOA 2GQUA 4JB1A 2I0KA 3I99A 1V97A 4BC7A 4BC9A 1HSKA 1N61C 4OALA 2Q4WA 4BBYA 3S1DA 1ZR6A 5FXEA
chains in the Genus database with same CATH superfamily
3LLBA 1QLUA 4DNSA 5HHZA 1F0XA 2RK5A 1AHVA 5AE1A 3FWAA 1N5WC 4PZFA 3PQBA 1WYGA 2VFTA 1W1OA 3AMZA 3NRZB 2W3SA 5L6FA 3RJAA 2UUVA 2BVGA 1W1KA 5G5GB 2WDWA 2Y3SA 1ZXIC 3VTEA 1W1JA 2PLSA 5AWVA 3DEDA 4XLOA 4JAYA 1W1QA 5G5HB 4UD8A 3D2DA 2VFSA 2Y4GA 1AHUA 4PYTA 1WVFA 1N63C 2P13A 2P3HA 3PM9A 3S1EA 3W8XA 1FFVC 1N5XA 3HRDC 1W1LA 3TSJA 2MBRA 3EJEB 5AE2A 3NVVB 1FO4A 2NQWA 1VDVA 3NS1B 3NVYB 3TX1A 5FXFA 5HMRA 2W54A 3RJ8A 5AE3A 3SR6B 3HSUA 3AN1A 2Q85A 2Y3RA 2OAIA 1E8FA 5I1VA 1WVEA 1DIQA 1W1SA 4ML8A 2E3TA 2QKNA 1QLTA 3DQ0A 1I19A 4PVEA 1RM6B 3BW7A 1FIQB 1SB3B 4PVHA 3FW8A 2O3GA 3FW9A 1W1RA 3W8WA 3KJMA 1AHZA 3W8ZA 3EUB3 3GSYA 2Y08A 2IPIA 3NVWB 3S1CA 3ETRB 1E8HA 1N62C 2VFRA 4BCAA 5K8EA 1N60C 2W55A 2VFUA 2W3RA 1DZNA 3S1FA 3D2JA 1MBBA 3C0PA 1JROA 3EJBB 2GQTA 1MBTA 3B9JB 1JRPA 5ADZA 3AM9A 2VAOA 5L6GA 1E0YA 2EXRA 2VFVA 5FXPA 3LAEA 2QPMA 1T3QC 5FXDA 2R8DA 5I1WA 1W1MA 1DIIA 4EC3A 3D2HA 2R2ZA 4O95A 2BVHA 4PWBA 5D79A 3NVZB 4PVJA 3EJDB 3JS8A 3TSHA 1UXYA 2PLIA 4ZOHB 3POPA 1FFUC 1E8GA 2AXRA 5HQXA 2P4PA 4MLAA 4PWCA 2BVFA 3FW7A 2YVSA 4PVKA 1VAOA 2GQUA 4JB1A 2I0KA 3I99A 1V97A 4BC7A 4BC9A 4HG0A 1HSKA 1N61C 4OALA 2Q4WA 4BBYA 2UUUA 3S1DA 1ZR6A 5FXEA
chains in the Genus database with same CATH topology
3LLBA 1QLUA 4DNSA 5HHZA 1F0XA 2RK5A 1AHVA 5AE1A 3FWAA 1N5WC 4PZFA 3PQBA 1WYGA 2VFTA 1W1OA 3AMZA 3NRZB 2W3SA 5L6FA 3RJAA 2UUVA 2BVGA 1W1KA 5G5GB 2WDWA 2Y3SA 1ZXIC 3VTEA 1W1JA 2PLSA 5AWVA 3DEDA 4XLOA 4JAYA 1W1QA 5G5HB 4UD8A 3D2DA 2VFSA 2Y4GA 1AHUA 4PYTA 1WVFA 1N63C 2P13A 2P3HA 3PM9A 3S1EA 3W8XA 1FFVC 1N5XA 3HRDC 1W1LA 3TSJA 2MBRA 5AE2A 3NVVB 1FO4A 2NQWA 1VDVA 3NS1B 3NVYB 3TX1A 5FXFA 5HMRA 2W54A 3RJ8A 5AE3A 3SR6B 3HSUA 3AN1A 2Q85A 2Y3RA 2OAIA 1E8FA 5I1VA 1WVEA 1DIQA 1W1SA 4ML8A 2E3TA 2QKNA 1QLTA 3DQ0A 1I19A 4PVEA 1RM6B 3BW7A 1FIQB 1SB3B 4PVHA 3FW8A 2O3GA 3FW9A 1W1RA 3W8WA 3KJMA 1AHZA 3W8ZA 3EUB3 3GSYA 2Y08A 2IPIA 3S1CA 3NVWB 3ETRB 1E8HA 1N62C 2VFRA 4BCAA 5K8EA 1N60C 2W55A 2VFUA 2W3RA 1DZNA 3S1FA 3D2JA 1MBBA 3C0PA 1JROA 2GQTA 1MBTA 3B9JB 1JRPA 5ADZA 3AM9A 2VAOA 5L6GA 1E0YA 2EXRA 2VFVA 5FXPA 3LAEA 2QPMA 1T3QC 5FXDA 2R8DA 5I1WA 1W1MA 1DIIA 4EC3A 3D2HA 2R2ZA 4O95A 2BVHA 4PWBA 5D79A 3NVZB 4PVJA 3JS8A 3TSHA 1UXYA 2PLIA 4ZOHB 3POPA 1FFUC 1E8GA 2AXRA 5HQXA 2P4PA 4MLAA 4PWCA 2BVFA 3FW7A 2YVSA 4PVKA 1VAOA 2GQUA 4JB1A 2I0KA 3I99A 1V97A 4BC7A 4BC9A 4HG0A 1HSKA 1N61C 4OALA 2Q4WA 4BBYA 2UUUA 3S1DA 1ZR6A 5FXEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1QLU A;  4DNS A;  5HHZ A;  1F0X A;  1AHV A;  5AE1 A;  3FWA A;  1N5W C;  4PZF A;  3PQB A;  1WYG A;  2VFT A;  1W1O A;  3AMZ A;  3NRZ B;  2W3S A;  5L6F A;  3RJA A;  2BVG A;  1W1K A;  2WDW A;  2Y3S A;  1ZXI C;  3VTE A;  1W1J A;  5AWV A;  4XLO A;  4JAY A;  1W1Q A;  4UD8 A;  3D2D A;  2VFS A;  2Y4G A;  1AHU A;  4PYT A;  1WVF A;  1N63 C;  3PM9 A;  3S1E A;  3W8X A;  1FFV C;  1N5X A;  1W1L A;  3TSJ A;  2MBR A;  5AE2 A;  1FO4 A;  1VDV A;  3NS1 B;  3TX1 A;  5FXF A;  5HMR A;  2W54 A;  3RJ8 A;  5AE3 A;  3SR6 B;  3HSU A;  3AN1 A;  2Q85 A;  2Y3R A;  1E8F A;  5I1V A;  1WVE A;  1DIQ A;  1W1S A;  4ML8 A;  2E3T A;  2QKN A;  1QLT A;  3DQ0 A;  1I19 A;  4PVE A;  3BW7 A;  1FIQ B;  4PVH A;  3FW8 A;  3FW9 A;  1W1R A;  3W8W A;  3KJM A;  1AHZ A;  3W8Z A;  3EUB 3;  3GSY A;  2Y08 A;  2IPI A;  3S1C A;  3ETR B;  1E8H A;  1N62 C;  2VFR A;  4BCA A;  5K8E A;  1N60 C;  2W55 A;  2VFU A;  2W3R A;  1DZN A;  3S1F A;  3D2J A;  1MBB A;  3C0P A;  1JRO A;  2GQT A;  1MBT A;  3B9J B;  5ADZ A;  3AM9 A;  2VAO A;  5L6G A;  1E0Y A;  2EXR A;  2VFV A;  5FXP A;  2QPM A;  1T3Q C;  5FXD A;  5I1W A;  1W1M A;  1DII A;  4EC3 A;  3D2H A;  4O95 A;  2BVH A;  4PWB A;  5D79 A;  3NVZ B;  4PVJ A;  3JS8 A;  3TSH A;  1UXY A;  4ZOH B;  3POP A;  1FFU C;  1E8G A;  2AXR A;  5HQX A;  4MLA A;  4PWC A;  2BVF A;  3FW7 A;  4PVK A;  1VAO A;  2GQU A;  4JB1 A;  2I0K A;  3I99 A;  1V97 A;  4BC7 A;  4BC9 A;  1HSK A;  1N61 C;  4OAL A;  2Q4W A;  4BBY A;  3S1D A;  1ZR6 A;  5FXE A; 
#chains in the Genus database with same CATH topology
 3LLB A;  1QLU A;  4DNS A;  5HHZ A;  1F0X A;  2RK5 A;  1AHV A;  5AE1 A;  3FWA A;  1N5W C;  4PZF A;  3PQB A;  1WYG A;  2VFT A;  1W1O A;  3AMZ A;  3NRZ B;  2W3S A;  5L6F A;  3RJA A;  2UUV A;  2BVG A;  1W1K A;  5G5G B;  2WDW A;  2Y3S A;  1ZXI C;  3VTE A;  1W1J A;  2PLS A;  5AWV A;  3DED A;  4XLO A;  4JAY A;  1W1Q A;  5G5H B;  4UD8 A;  3D2D A;  2VFS A;  2Y4G A;  1AHU A;  4PYT A;  1WVF A;  1N63 C;  2P13 A;  2P3H A;  3PM9 A;  3S1E A;  3W8X A;  1FFV C;  1N5X A;  3HRD C;  1W1L A;  3TSJ A;  2MBR A;  3EJE B;  5AE2 A;  3NVV B;  1FO4 A;  2NQW A;  1VDV A;  3NS1 B;  3NVY B;  3TX1 A;  5FXF A;  5HMR A;  2W54 A;  3RJ8 A;  5AE3 A;  3SR6 B;  3HSU A;  3AN1 A;  2Q85 A;  2Y3R A;  2OAI A;  1E8F A;  5I1V A;  1WVE A;  1DIQ A;  1W1S A;  4ML8 A;  2E3T A;  2QKN A;  1QLT A;  3DQ0 A;  1I19 A;  4PVE A;  1RM6 B;  3BW7 A;  1FIQ B;  1SB3 B;  4PVH A;  3FW8 A;  2O3G A;  3FW9 A;  1W1R A;  3W8W A;  3KJM A;  1AHZ A;  3W8Z A;  3EUB 3;  3GSY A;  2Y08 A;  2IPI A;  3NVW B;  3S1C A;  3ETR B;  1E8H A;  1N62 C;  2VFR A;  4BCA A;  5K8E A;  1N60 C;  2W55 A;  2VFU A;  2W3R A;  1DZN A;  3S1F A;  3D2J A;  1MBB A;  3C0P A;  1JRO A;  3EJB B;  2GQT A;  1MBT A;  3B9J B;  1JRP A;  5ADZ A;  3AM9 A;  2VAO A;  5L6G A;  1E0Y A;  2EXR A;  2VFV A;  5FXP A;  3LAE A;  2QPM A;  1T3Q C;  5FXD A;  2R8D A;  5I1W A;  1W1M A;  1DII A;  4EC3 A;  3D2H A;  2R2Z A;  4O95 A;  2BVH A;  4PWB A;  5D79 A;  3NVZ B;  4PVJ A;  3EJD B;  3JS8 A;  3TSH A;  1UXY A;  2PLI A;  4ZOH B;  3POP A;  1FFU C;  1E8G A;  2AXR A;  5HQX A;  2P4P A;  4MLA A;  4PWC A;  2BVF A;  3FW7 A;  2YVS A;  4PVK A;  1VAO A;  2GQU A;  4JB1 A;  2I0K A;  3I99 A;  1V97 A;  4BC7 A;  4BC9 A;  4HG0 A;  1HSK A;  1N61 C;  4OAL A;  2Q4W A;  4BBY A;  2UUU A;  3S1D A;  1ZR6 A;  5FXE A; 
#chains in the Genus database with same CATH homology
 3LLB A;  1QLU A;  4DNS A;  5HHZ A;  1F0X A;  2RK5 A;  1AHV A;  5AE1 A;  3FWA A;  1N5W C;  4PZF A;  3PQB A;  1WYG A;  2VFT A;  1W1O A;  3AMZ A;  3NRZ B;  2W3S A;  5L6F A;  3RJA A;  2UUV A;  2BVG A;  1W1K A;  5G5G B;  2WDW A;  2Y3S A;  1ZXI C;  3VTE A;  1W1J A;  2PLS A;  5AWV A;  3DED A;  4XLO A;  4JAY A;  1W1Q A;  5G5H B;  4UD8 A;  3D2D A;  2VFS A;  2Y4G A;  1AHU A;  4PYT A;  1WVF A;  1N63 C;  2P13 A;  2P3H A;  3PM9 A;  3S1E A;  3W8X A;  1FFV C;  1N5X A;  3HRD C;  1W1L A;  3TSJ A;  2MBR A;  5AE2 A;  3NVV B;  1FO4 A;  2NQW A;  1VDV A;  3NS1 B;  3NVY B;  3TX1 A;  5FXF A;  5HMR A;  2W54 A;  3RJ8 A;  5AE3 A;  3SR6 B;  3HSU A;  3AN1 A;  2Q85 A;  2Y3R A;  2OAI A;  1E8F A;  5I1V A;  1WVE A;  1DIQ A;  1W1S A;  4ML8 A;  2E3T A;  2QKN A;  1QLT A;  3DQ0 A;  1I19 A;  4PVE A;  1RM6 B;  3BW7 A;  1FIQ B;  1SB3 B;  4PVH A;  3FW8 A;  2O3G A;  3FW9 A;  1W1R A;  3W8W A;  3KJM A;  1AHZ A;  3W8Z A;  3EUB 3;  3GSY A;  2Y08 A;  2IPI A;  3S1C A;  3NVW B;  3ETR B;  1E8H A;  1N62 C;  2VFR A;  4BCA A;  5K8E A;  1N60 C;  2W55 A;  2VFU A;  2W3R A;  1DZN A;  3S1F A;  3D2J A;  1MBB A;  3C0P A;  1JRO A;  2GQT A;  1MBT A;  3B9J B;  1JRP A;  5ADZ A;  3AM9 A;  2VAO A;  5L6G A;  1E0Y A;  2EXR A;  2VFV A;  5FXP A;  3LAE A;  2QPM A;  1T3Q C;  5FXD A;  2R8D A;  5I1W A;  1W1M A;  1DII A;  4EC3 A;  3D2H A;  2R2Z A;  4O95 A;  2BVH A;  4PWB A;  5D79 A;  3NVZ B;  4PVJ A;  3JS8 A;  3TSH A;  1UXY A;  2PLI A;  4ZOH B;  3POP A;  1FFU C;  1E8G A;  2AXR A;  5HQX A;  2P4P A;  4MLA A;  4PWC A;  2BVF A;  3FW7 A;  2YVS A;  4PVK A;  1VAO A;  2GQU A;  4JB1 A;  2I0K A;  3I99 A;  1V97 A;  4BC7 A;  4BC9 A;  4HG0 A;  1HSK A;  1N61 C;  4OAL A;  2Q4W A;  4BBY A;  2UUU A;  3S1D A;  1ZR6 A;  5FXE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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