3FWAA

Structure of berberine bridge enzyme, c166a variant in complex with (s)-reticuline
Total Genus 169
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
169
sequence length
497
structure length
497
Chain Sequence
DLLSCLTFNGVRNHTVFSADSDSDFNRFLHLSIQNPLFQNSLISKPSAIILPGSKEELSNTIRCIRKGSWTIRLRSGGHSYEGLSYTSDTPFILIDLMNLNRVSIDLESETAWVESGSTLGELYYAITESSSKLGFTAGWAPTVGTGGHISGGGFGMMSRKYGLAADNVVDAILIDANGAILDRQAMGEDVFWAIRGGGGGVWGAIYAWKIKLLPVPEKVTVFRVTKNVAIDEATSLLHKWQFVAEELEEDFTLSVLGGADEKQVWLTMLGFHFGLKTVAKSTFDLLFPELGLVEEDYLEMSWGESFAYLAGLETVSQLNNRFLKFDERAFKTKVDLTKEPLPSKAFYGLLERLSKEPNGFIALNGFGGQMSKISSDFTPFPHRSGTRLMVEYIVAWNQSEQKKKTEFLDWLEKVYEFMKPFVSKNPRLGYVNHIDLDLGGIDWGNKTVVNNAIEISRSWGESYFLSNYERLIRAKTLIDPNNVFNHPQSIPPMANF
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural roles of biocovalent flaninylation in berberine bridge enzyme
rcsb
source organism Eschscholzia californica
molecule tags Flavoprotein
molecule keywords Reticuline oxidase
total genus 169
structure length 497
sequence length 497
ec nomenclature ec 1.21.3.3: Reticuline oxidase.
pdb deposition date 2009-01-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF08031 BBE Berberine and berberine like
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 3fwaA01
3.30.465.50 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 3fwaA02
3.40.462.20 Alpha Beta 3-Layer(aba) Sandwich Vanillyl-alcohol Oxidase; Chain A, domain 3 Vanillyl-alcohol Oxidase; Chain A, domain 3 3fwaA03
1E8HA 3TSHA 3S1EA 2EXRA 3AM9A 5ADZA 2AXRA 1FFVC 1N62C 3W8XA 1VAOA 4O95A 3NRZB 3B9JB 2GQUA 1MBBA 2BVGA 4PVKA 4EC3A 3BW7A 3TSJA 2Y08A 2VFUA 1AHZA 4PZFA 2Y3SA 3S1FA 4UD8A 1FO4A 1T3QC 1QLTA 3FW9A 3NS1B 1W1QA 1W1KA 5L6FA 1FFUC 4PVEA 1N5WC 4XLOA 1I19A 4BC9A 1JROA 5HQXA 2VFSA 3PM9A 4PWBA 4ZOHB 1WVFA 5AE1A 3JS8A 3W8WA 4JB1A 2WDWA 3I99A 2BVHA 1WVEA 5I1WA 4OALA 3RJ8A 1W1OA 5FXFA 1QLUA 2W3SA 2W54A 3EUB3 3S1DA 4ML8A 1E8GA 3FW8A 4PYTA 3GSYA 1N60C 1W1RA 1N5XA 2VFTA 2VFRA 3D2HA 1N63C 2QKNA 2W55A 4PWCA 3SR6B 4PVJA 3W8ZA 5K8EA 2E3TA 2Q85A 2Q4WA 1HSKA 3C0PA 1E0YA 1FIQB 3HSUA 3ETRB 2W3RA 5HHZA 5AWVA 1E8FA 2QPMA 5I1VA 3S1CA 3D2DA 1V97A 2VFVA 4DNSA 5FXDA 1W1LA 1F0XA 2GQTA 2I0KA 3POPA 1UXYA 2BVFA 3D2JA 4BC7A 2MBRA 3VTEA 3PQBA 3FWAA 1N61C 4MLAA 3DQ0A 4PVHA 3FW7A 1VDVA 1DZNA 1W1MA 5FXPA 1WYGA 5D79A 5AE2A 2Y4GA 4BCAA 3TX1A 3AMZA 4BBYA 2Y3RA 1W1JA 3KJMA 1ZR6A 3AN1A 5AE3A 1AHUA 3NVZB 2VAOA 1W1SA 1MBTA 5HMRA 5FXEA 1DIIA 1AHVA 4JAYA 1DIQA 5L6GA 2IPIA 3RJAA 1ZXIC
chains in the Genus database with same CATH superfamily
1RM6B 1E8HA 3NVVB 3TSHA 3EJEB 3S1EA 2EXRA 3AM9A 5ADZA 2AXRA 1FFVC 1N62C 3W8XA 1VAOA 4O95A 3NRZB 3B9JB 2GQUA 1MBBA 2BVGA 4PVKA 4EC3A 3BW7A 3TSJA 2Y08A 2VFUA 1AHZA 4PZFA 2Y3SA 3S1FA 4UD8A 1FO4A 1T3QC 1QLTA 3FW9A 3NS1B 5G5HB 1W1QA 1W1KA 5L6FA 1FFUC 2UUUA 4PVEA 1N5WC 3EJBB 2NQWA 2P3HA 4XLOA 1I19A 4BC9A 1JROA 5HQXA 2VFSA 3PM9A 4PWBA 3EJDB 4ZOHB 2PLIA 1WVFA 1SB3B 4HG0A 5AE1A 3JS8A 3W8WA 4JB1A 3LLBA 2WDWA 3I99A 2BVHA 1WVEA 5I1WA 4OALA 3RJ8A 1W1OA 5FXFA 1QLUA 2W3SA 2W54A 3NVYB 3EUB3 3S1DA 4ML8A 3DEDA 1E8GA 3FW8A 4PYTA 3GSYA 1N60C 1W1RA 2YVSA 1N5XA 2VFTA 2VFRA 2R2ZA 3D2HA 1N63C 2QKNA 2W55A 4PWCA 3SR6B 4PVJA 3W8ZA 5K8EA 2E3TA 2Q85A 2P13A 2Q4WA 1HSKA 3C0PA 1E0YA 1FIQB 3HSUA 3ETRB 2OAIA 2W3RA 5HHZA 5AWVA 1E8FA 2QPMA 2P4PA 5I1VA 3S1CA 3D2DA 1V97A 2VFVA 4DNSA 5FXDA 1W1LA 1F0XA 2GQTA 2I0KA 3POPA 1UXYA 2BVFA 3D2JA 4BC7A 2MBRA 3VTEA 3PQBA 3FWAA 1N61C 4MLAA 3DQ0A 4PVHA 3NVWB 3LAEA 3FW7A 1VDVA 1DZNA 1W1MA 5FXPA 1WYGA 5D79A 5AE2A 2Y4GA 4BCAA 3TX1A 3AMZA 5G5GB 4BBYA 2Y3RA 1W1JA 3KJMA 1ZR6A 2PLSA 3AN1A 5AE3A 2O3GA 2RK5A 2UUVA 1AHUA 3NVZB 2VAOA 1W1SA 1MBTA 5HMRA 5FXEA 1DIIA 1AHVA 4JAYA 2R8DA 3HRDC 1DIQA 5L6GA 1JRPA 2IPIA 3RJAA 1ZXIC
chains in the Genus database with same CATH topology
1RM6B 1E8HA 3NVVB 3TSHA 3S1EA 2EXRA 3AM9A 5ADZA 2AXRA 1FFVC 1N62C 3W8XA 1VAOA 4O95A 3NRZB 3B9JB 2GQUA 1MBBA 2BVGA 4PVKA 4EC3A 3BW7A 3TSJA 2Y08A 2VFUA 1AHZA 4PZFA 2Y3SA 3S1FA 4UD8A 1FO4A 1T3QC 1QLTA 3FW9A 3NS1B 5G5HB 1W1QA 1W1KA 5L6FA 1FFUC 2UUUA 4PVEA 1N5WC 2P3HA 2NQWA 4XLOA 1I19A 4BC9A 1JROA 5HQXA 2VFSA 3PM9A 4PWBA 4ZOHB 2PLIA 1WVFA 1SB3B 4HG0A 5AE1A 3JS8A 3W8WA 4JB1A 3LLBA 2WDWA 3I99A 2BVHA 1WVEA 5I1WA 4OALA 3RJ8A 1W1OA 5FXFA 1QLUA 2W3SA 2W54A 3NVYB 3EUB3 3S1DA 4ML8A 3DEDA 1E8GA 3FW8A 4PYTA 3GSYA 1N60C 1W1RA 2YVSA 1N5XA 2VFTA 2VFRA 2R2ZA 3D2HA 1N63C 2QKNA 2W55A 4PWCA 3SR6B 4PVJA 3W8ZA 5K8EA 2E3TA 2Q85A 2P13A 2Q4WA 1HSKA 3C0PA 1E0YA 1FIQB 3HSUA 3ETRB 2OAIA 2W3RA 5HHZA 5AWVA 1E8FA 2QPMA 2P4PA 5I1VA 3S1CA 3D2DA 1V97A 2VFVA 4DNSA 5FXDA 1W1LA 1F0XA 2GQTA 2I0KA 3POPA 1UXYA 2BVFA 3D2JA 4BC7A 2MBRA 3VTEA 3PQBA 3FWAA 1N61C 4MLAA 3DQ0A 4PVHA 3LAEA 3NVWB 3FW7A 1VDVA 1DZNA 1W1MA 5FXPA 1WYGA 5D79A 5AE2A 2Y4GA 4BCAA 3TX1A 3AMZA 5G5GB 4BBYA 2Y3RA 1W1JA 3KJMA 1ZR6A 2PLSA 3AN1A 5AE3A 2O3GA 2RK5A 2UUVA 1AHUA 3NVZB 2VAOA 1W1SA 1MBTA 5HMRA 5FXEA 1DIIA 1AHVA 4JAYA 2R8DA 3HRDC 1DIQA 5L6GA 1JRPA 2IPIA 3RJAA 1ZXIC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1E8H A;  3TSH A;  3S1E A;  2EXR A;  3AM9 A;  5ADZ A;  2AXR A;  1FFV C;  1N62 C;  3W8X A;  1VAO A;  4O95 A;  3NRZ B;  3B9J B;  2GQU A;  1MBB A;  2BVG A;  4PVK A;  4EC3 A;  3BW7 A;  3TSJ A;  2Y08 A;  2VFU A;  1AHZ A;  4PZF A;  2Y3S A;  3S1F A;  4UD8 A;  1FO4 A;  1T3Q C;  1QLT A;  3FW9 A;  3NS1 B;  1W1Q A;  1W1K A;  5L6F A;  1FFU C;  4PVE A;  1N5W C;  4XLO A;  1I19 A;  4BC9 A;  1JRO A;  5HQX A;  2VFS A;  3PM9 A;  4PWB A;  4ZOH B;  1WVF A;  5AE1 A;  3JS8 A;  3W8W A;  4JB1 A;  2WDW A;  3I99 A;  2BVH A;  1WVE A;  5I1W A;  4OAL A;  3RJ8 A;  1W1O A;  5FXF A;  1QLU A;  2W3S A;  2W54 A;  3EUB 3;  3S1D A;  4ML8 A;  1E8G A;  3FW8 A;  4PYT A;  3GSY A;  1N60 C;  1W1R A;  1N5X A;  2VFT A;  2VFR A;  3D2H A;  1N63 C;  2QKN A;  2W55 A;  4PWC A;  3SR6 B;  4PVJ A;  3W8Z A;  5K8E A;  2E3T A;  2Q85 A;  2Q4W A;  1HSK A;  3C0P A;  1E0Y A;  1FIQ B;  3HSU A;  3ETR B;  2W3R A;  5HHZ A;  5AWV A;  1E8F A;  2QPM A;  5I1V A;  3S1C A;  3D2D A;  1V97 A;  2VFV A;  4DNS A;  5FXD A;  1W1L A;  1F0X A;  2GQT A;  2I0K A;  3POP A;  1UXY A;  2BVF A;  3D2J A;  4BC7 A;  2MBR A;  3VTE A;  3PQB A;  3FWA A;  1N61 C;  4MLA A;  3DQ0 A;  4PVH A;  3FW7 A;  1VDV A;  1DZN A;  1W1M A;  5FXP A;  1WYG A;  5D79 A;  5AE2 A;  2Y4G A;  4BCA A;  3TX1 A;  3AMZ A;  4BBY A;  2Y3R A;  1W1J A;  3KJM A;  1ZR6 A;  3AN1 A;  5AE3 A;  1AHU A;  3NVZ B;  2VAO A;  1W1S A;  1MBT A;  5HMR A;  5FXE A;  1DII A;  1AHV A;  4JAY A;  1DIQ A;  5L6G A;  2IPI A;  3RJA A;  1ZXI C; 
#chains in the Genus database with same CATH topology
 1RM6 B;  1E8H A;  3NVV B;  3TSH A;  3EJE B;  3S1E A;  2EXR A;  3AM9 A;  5ADZ A;  2AXR A;  1FFV C;  1N62 C;  3W8X A;  1VAO A;  4O95 A;  3NRZ B;  3B9J B;  2GQU A;  1MBB A;  2BVG A;  4PVK A;  4EC3 A;  3BW7 A;  3TSJ A;  2Y08 A;  2VFU A;  1AHZ A;  4PZF A;  2Y3S A;  3S1F A;  4UD8 A;  1FO4 A;  1T3Q C;  1QLT A;  3FW9 A;  3NS1 B;  5G5H B;  1W1Q A;  1W1K A;  5L6F A;  1FFU C;  2UUU A;  4PVE A;  1N5W C;  3EJB B;  2NQW A;  2P3H A;  4XLO A;  1I19 A;  4BC9 A;  1JRO A;  5HQX A;  2VFS A;  3PM9 A;  4PWB A;  3EJD B;  4ZOH B;  2PLI A;  1WVF A;  1SB3 B;  4HG0 A;  5AE1 A;  3JS8 A;  3W8W A;  4JB1 A;  3LLB A;  2WDW A;  3I99 A;  2BVH A;  1WVE A;  5I1W A;  4OAL A;  3RJ8 A;  1W1O A;  5FXF A;  1QLU A;  2W3S A;  2W54 A;  3NVY B;  3EUB 3;  3S1D A;  4ML8 A;  3DED A;  1E8G A;  3FW8 A;  4PYT A;  3GSY A;  1N60 C;  1W1R A;  2YVS A;  1N5X A;  2VFT A;  2VFR A;  2R2Z A;  3D2H A;  1N63 C;  2QKN A;  2W55 A;  4PWC A;  3SR6 B;  4PVJ A;  3W8Z A;  5K8E A;  2E3T A;  2Q85 A;  2P13 A;  2Q4W A;  1HSK A;  3C0P A;  1E0Y A;  1FIQ B;  3HSU A;  3ETR B;  2OAI A;  2W3R A;  5HHZ A;  5AWV A;  1E8F A;  2QPM A;  2P4P A;  5I1V A;  3S1C A;  3D2D A;  1V97 A;  2VFV A;  4DNS A;  5FXD A;  1W1L A;  1F0X A;  2GQT A;  2I0K A;  3POP A;  1UXY A;  2BVF A;  3D2J A;  4BC7 A;  2MBR A;  3VTE A;  3PQB A;  3FWA A;  1N61 C;  4MLA A;  3DQ0 A;  4PVH A;  3NVW B;  3LAE A;  3FW7 A;  1VDV A;  1DZN A;  1W1M A;  5FXP A;  1WYG A;  5D79 A;  5AE2 A;  2Y4G A;  4BCA A;  3TX1 A;  3AMZ A;  5G5G B;  4BBY A;  2Y3R A;  1W1J A;  3KJM A;  1ZR6 A;  2PLS A;  3AN1 A;  5AE3 A;  2O3G A;  2RK5 A;  2UUV A;  1AHU A;  3NVZ B;  2VAO A;  1W1S A;  1MBT A;  5HMR A;  5FXE A;  1DII A;  1AHV A;  4JAY A;  2R8D A;  3HRD C;  1DIQ A;  5L6G A;  1JRP A;  2IPI A;  3RJA A;  1ZXI C; 
#chains in the Genus database with same CATH homology
 1RM6 B;  1E8H A;  3NVV B;  3TSH A;  3S1E A;  2EXR A;  3AM9 A;  5ADZ A;  2AXR A;  1FFV C;  1N62 C;  3W8X A;  1VAO A;  4O95 A;  3NRZ B;  3B9J B;  2GQU A;  1MBB A;  2BVG A;  4PVK A;  4EC3 A;  3BW7 A;  3TSJ A;  2Y08 A;  2VFU A;  1AHZ A;  4PZF A;  2Y3S A;  3S1F A;  4UD8 A;  1FO4 A;  1T3Q C;  1QLT A;  3FW9 A;  3NS1 B;  5G5H B;  1W1Q A;  1W1K A;  5L6F A;  1FFU C;  2UUU A;  4PVE A;  1N5W C;  2P3H A;  2NQW A;  4XLO A;  1I19 A;  4BC9 A;  1JRO A;  5HQX A;  2VFS A;  3PM9 A;  4PWB A;  4ZOH B;  2PLI A;  1WVF A;  1SB3 B;  4HG0 A;  5AE1 A;  3JS8 A;  3W8W A;  4JB1 A;  3LLB A;  2WDW A;  3I99 A;  2BVH A;  1WVE A;  5I1W A;  4OAL A;  3RJ8 A;  1W1O A;  5FXF A;  1QLU A;  2W3S A;  2W54 A;  3NVY B;  3EUB 3;  3S1D A;  4ML8 A;  3DED A;  1E8G A;  3FW8 A;  4PYT A;  3GSY A;  1N60 C;  1W1R A;  2YVS A;  1N5X A;  2VFT A;  2VFR A;  2R2Z A;  3D2H A;  1N63 C;  2QKN A;  2W55 A;  4PWC A;  3SR6 B;  4PVJ A;  3W8Z A;  5K8E A;  2E3T A;  2Q85 A;  2P13 A;  2Q4W A;  1HSK A;  3C0P A;  1E0Y A;  1FIQ B;  3HSU A;  3ETR B;  2OAI A;  2W3R A;  5HHZ A;  5AWV A;  1E8F A;  2QPM A;  2P4P A;  5I1V A;  3S1C A;  3D2D A;  1V97 A;  2VFV A;  4DNS A;  5FXD A;  1W1L A;  1F0X A;  2GQT A;  2I0K A;  3POP A;  1UXY A;  2BVF A;  3D2J A;  4BC7 A;  2MBR A;  3VTE A;  3PQB A;  3FWA A;  1N61 C;  4MLA A;  3DQ0 A;  4PVH A;  3LAE A;  3NVW B;  3FW7 A;  1VDV A;  1DZN A;  1W1M A;  5FXP A;  1WYG A;  5D79 A;  5AE2 A;  2Y4G A;  4BCA A;  3TX1 A;  3AMZ A;  5G5G B;  4BBY A;  2Y3R A;  1W1J A;  3KJM A;  1ZR6 A;  2PLS A;  3AN1 A;  5AE3 A;  2O3G A;  2RK5 A;  2UUV A;  1AHU A;  3NVZ B;  2VAO A;  1W1S A;  1MBT A;  5HMR A;  5FXE A;  1DII A;  1AHV A;  4JAY A;  2R8D A;  3HRD C;  1DIQ A;  5L6G A;  1JRP A;  2IPI A;  3RJA A;  1ZXI C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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