3G6EU

Co-crystal structure of homoharringtonine bound to the large ribosomal subunit
Total Genus 10
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
53
structure length
53
Chain Sequence
RECDYCGTDIEPGTGTMFVHKDGATTHFCSSKCENNADLGREARNLEWTDTAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Ribosome
molecule keywords 23S ribosomal RNA
publication title U2504 determines the species specificity of the A-site cleft antibiotics: the structures of tiamulin, homoharringtonine, and bruceantin bound to the ribosome.
pubmed doi rcsb
total genus 10
structure length 53
sequence length 53
ec nomenclature
pdb deposition date 2009-02-06
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.170.20 Mainly Beta Roll Ribosomal Protein L24e; Chain: T; Ribosomal Protein L24e; Chain: T; 3g6eU00
1QVGT 3CPWT 3G71U 1KC8V 3CC2U 1Q82V 3CC4U 1VQ9U 3CCLU 3CCEU 1YITU 1JJ2T 1VQNU 3CD6U 3CMAU 3CMEU 1VQ7U 1K8AV 3CCRU 1W2BT 1YJ9U 1VQLU 1Q86V 1VQOU 1Q7YV 3CCSU 1M1KV 3CCMU 3CCVU 1VQ4U 3I55U 3CCUU 1K9MV 1VQ5U 1YJNU 2OTJU 3CXCT 3CCJU 1YJWU 3CCQU 1NJIV 2QA4U 3G4SU 1K73V 3G6EU 2QEXU 1VQPU 1YI2U 3OW2T 1YHQU 1S72U 1VQ8U 3CC7U 1YIJU 1VQMU 3I56U 1VQKU 1M90V 1N8RV 2OTLU 1QVFT 1KQST 5AN9G 1KD1V 1Q81V 1VQ6U
chains in the Genus database with same CATH superfamily
4UY8X 1JJDA 3ABOA 2JZ6A 3CCLU 1JJ2T 1VQNU 1K8AV 5H1SY 1Q7YV 1YJNU 2OTJU 3AO0A 3ABRA 1NJIV 1YI2U 2QEXU 3CC7U 1S72U 1VQKU 1M90V 1N8RV 1KQST 1KD1V 1Q81V 3CCEU 1VQ7U 3CCRU 1YJ9U 1VQLU 1M1KV 3CCVU 3I55U 3CXCT 1YJWU 3CCQU 1K73V 1VQPU 1YHQU 1YIJU 2OTLU 1QVFT 3ANYA 3CPWT 2QEZA 3G71U 3CD6U 1W2BT 3CCSU 3J7ZX 5DM6U 3CCUU 1K9MV 3G6EU 1VQ8U 3ABQA 1VQ6U 3ABSA 1QVGT 1KC8V 3CC2U 1Q82V 3CC4U 1VQ9U 1YITU 3CMAU 3CMEU 1Q86V 1VQOU 1VQ4U 3CCMU 5MLCY 1VQ5U 3CCJU 2QA4U 3G4SU 3OW2T 1VQMU 3I56U 5AN9G
chains in the Genus database with same CATH topology
1QVGT 3CPWT 3G71U 1KC8V 1JJDA 3CC2U 1Q82V 3CC4U 1VQ9U 3CCLU 3CCEU 1YITU 1JJ2T 1VQNU 3CD6U 3CMAU 3CMEU 1VQ7U 1K8AV 3CCRU 1W2BT 1YJ9U 1VQLU 1Q86V 1VQOU 1Q7YV 3CCSU 1M1KV 3CCMU 3CCVU 1VQ4U 3I55U 3CCUU 1K9MV 1VQ5U 1YJNU 2OTJU 3CXCT 3CCJU 1YJWU 3CCQU 1NJIV 2QA4U 3G4SU 1K73V 3G6EU 2QEXU 1VQPU 1YI2U 3OW2T 1YHQU 1S72U 1VQ8U 3CC7U 1YIJU 1VQMU 3I56U 1VQKU 1M90V 1N8RV 2OTLU 1QVFT 1KQST 5AN9G 1KD1V 1Q81V 1VQ6U
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1QVG T;  3CPW T;  3G71 U;  1KC8 V;  3CC2 U;  1Q82 V;  3CC4 U;  1VQ9 U;  3CCL U;  3CCE U;  1YIT U;  1JJ2 T;  1VQN U;  3CD6 U;  3CMA U;  3CME U;  1VQ7 U;  1K8A V;  3CCR U;  1W2B T;  1YJ9 U;  1VQL U;  1Q86 V;  1VQO U;  1Q7Y V;  3CCS U;  1M1K V;  3CCM U;  3CCV U;  1VQ4 U;  3I55 U;  3CCU U;  1K9M V;  1VQ5 U;  1YJN U;  2OTJ U;  3CXC T;  3CCJ U;  1YJW U;  3CCQ U;  1NJI V;  2QA4 U;  3G4S U;  1K73 V;  3G6E U;  2QEX U;  1VQP U;  1YI2 U;  3OW2 T;  1YHQ U;  1S72 U;  1VQ8 U;  3CC7 U;  1YIJ U;  1VQM U;  3I56 U;  1VQK U;  1M90 V;  1N8R V;  2OTL U;  1QVF T;  1KQS T;  5AN9 G;  1KD1 V;  1Q81 V;  1VQ6 U; 
#chains in the Genus database with same CATH topology
 4UY8 X;  1JJD A;  3ABO A;  2JZ6 A;  3CCL U;  1JJ2 T;  1VQN U;  1K8A V;  5H1S Y;  1Q7Y V;  1YJN U;  2OTJ U;  3AO0 A;  3ABR A;  1NJI V;  1YI2 U;  2QEX U;  3CC7 U;  1S72 U;  1VQK U;  1M90 V;  1N8R V;  1KQS T;  1KD1 V;  1Q81 V;  3CCE U;  1VQ7 U;  3CCR U;  1YJ9 U;  1VQL U;  1M1K V;  3CCV U;  3I55 U;  3CXC T;  1YJW U;  3CCQ U;  1K73 V;  1VQP U;  1YHQ U;  1YIJ U;  2OTL U;  1QVF T;  3ANY A;  3CPW T;  2QEZ A;  3G71 U;  3CD6 U;  1W2B T;  3CCS U;  3J7Z X;  5DM6 U;  3CCU U;  1K9M V;  3G6E U;  1VQ8 U;  3ABQ A;  1VQ6 U;  3ABS A;  1QVG T;  1KC8 V;  3CC2 U;  1Q82 V;  3CC4 U;  1VQ9 U;  1YIT U;  3CMA U;  3CME U;  1Q86 V;  1VQO U;  1VQ4 U;  3CCM U;  5MLC Y;  1VQ5 U;  3CCJ U;  2QA4 U;  3G4S U;  3OW2 T;  1VQM U;  3I56 U;  5AN9 G; 
#chains in the Genus database with same CATH homology
 1QVG T;  3CPW T;  3G71 U;  1KC8 V;  1JJD A;  3CC2 U;  1Q82 V;  3CC4 U;  1VQ9 U;  3CCL U;  3CCE U;  1YIT U;  1JJ2 T;  1VQN U;  3CD6 U;  3CMA U;  3CME U;  1VQ7 U;  1K8A V;  3CCR U;  1W2B T;  1YJ9 U;  1VQL U;  1Q86 V;  1VQO U;  1Q7Y V;  3CCS U;  1M1K V;  3CCM U;  3CCV U;  1VQ4 U;  3I55 U;  3CCU U;  1K9M V;  1VQ5 U;  1YJN U;  2OTJ U;  3CXC T;  3CCJ U;  1YJW U;  3CCQ U;  1NJI V;  2QA4 U;  3G4S U;  1K73 V;  3G6E U;  2QEX U;  1VQP U;  1YI2 U;  3OW2 T;  1YHQ U;  1S72 U;  1VQ8 U;  3CC7 U;  1YIJ U;  1VQM U;  3I56 U;  1VQK U;  1M90 V;  1N8R V;  2OTL U;  1QVF T;  1KQS T;  5AN9 G;  1KD1 V;  1Q81 V;  1VQ6 U; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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