3G71E

Co-crystal structure of bruceantin bound to the large ribosomal subunit
Total Genus 37
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
172
structure length
172
Chain Sequence
PRVELEIPEDVDAEQDHLDITVEGDNGSVTRRLWYPDIDVSVDGDTVVIESDEDNAKTMSTIGTFQSHIENMFHGVTEGWEYGMEVFYSHFPMQVNVEGDEVVIENFLGEKAPRRTTIHGDTDVEIDGEELTVSGPDIEAVGQTAADIEQLTRINDKDVRVFQDGVYITRKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title U2504 determines the species specificity of the A-site cleft antibiotics: the structures of tiamulin, homoharringtonine, and bruceantin bound to the ribosome.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S ribosomal RNA
total genus 37
structure length 172
sequence length 172
ec nomenclature
pdb deposition date 2009-02-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00347 Ribosomal_L6 Ribosomal protein L6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3g71E02
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3g71E01
2QEXE 1N8RG 5JVHE 1KC8G 3PIPE 3PIOE 1YJWE 3CXCE 5GAGG 1YITE 5GAHG 3CF5E 1VQOE 3CCEE 1Q7YG 2CQLA 4WFNE 4WFAE 4WF9E 4UY8G 3CCRE 1M90G 1YIJE 1VQ5E 2QA4E 1W2BE 5H1SI 2OTLE 3CD6E 1QVFE 3CCUE 1VQNE 5AN9B 3G4SE 2ZJPE 2ZJRE 1VQ9E 3CC2E 3CCLE 1K73G 4IOAE 4WCEE 1VQPE 1VQKE 3CMEE 3CCVE 5DM7E 5GADG 5GAEG 3CC7E 1Q81G 1M1KG 3CMAE 1JJ2E 5HL7E 1VQ7E 1VQ4E 3CCQE 3I56E 1KQSE 1S72E 1RL6A 1VQME 3I55E 1Q86G 5MLCH 3CCME 3OW2E 1K9MG 4IO9E 3CC4E 3CCSE 3CPWE 1QVGE 1NJIG 2OTJE 4WFBE 3G6EE 4U67E 4IOCE 1Q82G 1VQ8E 2ZJQE 5JVGE 1YJNE 1YJ9E 1YI2E 3CCJE 1K8AG 5DM6E 3G71E 1VQLE 1KD1G 3J7ZG 1YHQE 3DLLE 1VQ6E
chains in the Genus database with same CATH superfamily
1FJ1E 2QEXE 1N8RG 5JVHE 3IGEA 1KC8G 3PIPE 1P4PA 3PIOE 1YJWE 3CXCE 5GAGG 1YITE 5GAHG 3CF5E 1VQOE 3CCEE 2OY5O 1Q7YG 2CQLA 4WFNE 4WFAE 4WF9E 4UY8G 3CCRE 1M90G 3IG9A 1YIJE 1VQ5E 2QA4E 1W2BE 5H1SI 2OTLE 3CD6E 2OY7A 1QVFE 3CCUE 1VQNE 5B11O 5AN9B 3EC5A 3G4SE 2HKDA 2ZJPE 1RJLC 2ZJRE 1VQ9E 3CC2E 3CCLE 2FKJA 1K73G 4IOAE 4WCEE 5B3MO 1VQPE 1OSPO 1VQKE 3CMEE 3CCVE 5DM7E 2OY1O 5GADG 5GAEG 3CC7E 2OL6O 3CKGA 1Q81G 1M1KG 2OY8A 3CMAE 1JJ2E 3AUMO 5HL7E 1VQ7E 1VQ4E 3CCQE 3I56E 5B2AO 1KQSE 1S72E 1RL6A 2PI3O 2OYBO 3CKFA 1VQME 3I55E 1Q86G 5B10O 5MLCH 3CCME 3OW2E 1K9MG 4IO9E 2AF5A 3CC4E 2I5VO 3CCSE 3CPWE 1QVGE 1NJIG 2OTJE 4WFBE 3G6EE 2OL7A 4U67E 4IOCE 2I5ZO 1Q82G 1VQ8E 2ZJQE 5JVGE 1YJNE 1YJ9E 1YI2E 3CCJE 2FKGA 1K8AG 5DM6E 3G71E 1VQLE 1KD1G 3J7ZG 1YHQE 3DLLE 2OL8O 2G8CO 1VQ6E
chains in the Genus database with same CATH topology
2QEXE 1N8RG 5JVHE 1KC8G 3PIPE 3PIOE 1YJWE 3CXCE 5GAGG 1YITE 5GAHG 3CF5E 1VQOE 3CCEE 1Q7YG 2CQLA 4WFNE 4WFAE 4WF9E 4UY8G 3CCRE 1M90G 1YIJE 1VQ5E 2QA4E 1W2BE 5H1SI 2OTLE 3CD6E 1QVFE 3CCUE 1VQNE 5AN9B 3G4SE 2ZJPE 2ZJRE 1VQ9E 3CC2E 3CCLE 1K73G 4IOAE 4WCEE 1VQPE 1VQKE 3CMEE 3CCVE 5DM7E 5GADG 5GAEG 3CC7E 1Q81G 1M1KG 3CMAE 1JJ2E 5HL7E 1VQ7E 1VQ4E 3CCQE 3I56E 1KQSE 1S72E 1RL6A 1VQME 3I55E 1Q86G 5MLCH 3CCME 3OW2E 1K9MG 4IO9E 3CC4E 3CCSE 3CPWE 1QVGE 1NJIG 2OTJE 4WFBE 3G6EE 4U67E 4IOCE 1Q82G 1VQ8E 2ZJQE 5JVGE 1YJNE 1YJ9E 1YI2E 3CCJE 1K8AG 5DM6E 3G71E 1VQLE 1KD1G 3J7ZG 1YHQE 3DLLE 1VQ6E
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2QEX E;  1N8R G;  5JVH E;  1KC8 G;  3PIP E;  3PIO E;  1YJW E;  3CXC E;  5GAG G;  1YIT E;  5GAH G;  3CF5 E;  1VQO E;  3CCE E;  1Q7Y G;  2CQL A;  4WFN E;  4WFA E;  4WF9 E;  4UY8 G;  3CCR E;  1M90 G;  1YIJ E;  1VQ5 E;  2QA4 E;  1W2B E;  5H1S I;  2OTL E;  3CD6 E;  1QVF E;  3CCU E;  1VQN E;  5AN9 B;  3G4S E;  2ZJP E;  2ZJR E;  1VQ9 E;  3CC2 E;  3CCL E;  1K73 G;  4IOA E;  4WCE E;  1VQP E;  1VQK E;  3CME E;  3CCV E;  5DM7 E;  5GAD G;  5GAE G;  3CC7 E;  1Q81 G;  1M1K G;  3CMA E;  1JJ2 E;  5HL7 E;  1VQ7 E;  1VQ4 E;  3CCQ E;  3I56 E;  1KQS E;  1S72 E;  1RL6 A;  1VQM E;  3I55 E;  1Q86 G;  5MLC H;  3CCM E;  3OW2 E;  1K9M G;  4IO9 E;  3CC4 E;  3CCS E;  3CPW E;  1QVG E;  1NJI G;  2OTJ E;  4WFB E;  3G6E E;  4U67 E;  4IOC E;  1Q82 G;  1VQ8 E;  2ZJQ E;  5JVG E;  1YJN E;  1YJ9 E;  1YI2 E;  3CCJ E;  1K8A G;  5DM6 E;  3G71 E;  1VQL E;  1KD1 G;  3J7Z G;  1YHQ E;  3DLL E;  1VQ6 E; 
#chains in the Genus database with same CATH topology
 1FJ1 E;  2QEX E;  1N8R G;  5JVH E;  3IGE A;  1KC8 G;  3PIP E;  1P4P A;  3PIO E;  1YJW E;  3CXC E;  5GAG G;  1YIT E;  5GAH G;  3CF5 E;  1VQO E;  3CCE E;  2OY5 O;  1Q7Y G;  2CQL A;  4WFN E;  4WFA E;  4WF9 E;  4UY8 G;  3CCR E;  1M90 G;  3IG9 A;  1YIJ E;  1VQ5 E;  2QA4 E;  1W2B E;  5H1S I;  2OTL E;  3CD6 E;  2OY7 A;  1QVF E;  3CCU E;  1VQN E;  5B11 O;  5AN9 B;  3EC5 A;  3G4S E;  2HKD A;  2ZJP E;  1RJL C;  2ZJR E;  1VQ9 E;  3CC2 E;  3CCL E;  2FKJ A;  1K73 G;  4IOA E;  4WCE E;  5B3M O;  1VQP E;  1OSP O;  1VQK E;  3CME E;  3CCV E;  5DM7 E;  2OY1 O;  5GAD G;  5GAE G;  3CC7 E;  2OL6 O;  3CKG A;  1Q81 G;  1M1K G;  2OY8 A;  3CMA E;  1JJ2 E;  3AUM O;  5HL7 E;  1VQ7 E;  1VQ4 E;  3CCQ E;  3I56 E;  5B2A O;  1KQS E;  1S72 E;  1RL6 A;  2PI3 O;  2OYB O;  3CKF A;  1VQM E;  3I55 E;  1Q86 G;  5B10 O;  5MLC H;  3CCM E;  3OW2 E;  1K9M G;  4IO9 E;  2AF5 A;  3CC4 E;  2I5V O;  3CCS E;  3CPW E;  1QVG E;  1NJI G;  2OTJ E;  4WFB E;  3G6E E;  2OL7 A;  4U67 E;  4IOC E;  2I5Z O;  1Q82 G;  1VQ8 E;  2ZJQ E;  5JVG E;  1YJN E;  1YJ9 E;  1YI2 E;  3CCJ E;  2FKG A;  1K8A G;  5DM6 E;  3G71 E;  1VQL E;  1KD1 G;  3J7Z G;  1YHQ E;  3DLL E;  2OL8 O;  2G8C O;  1VQ6 E; 
#chains in the Genus database with same CATH homology
 2QEX E;  1N8R G;  5JVH E;  1KC8 G;  3PIP E;  3PIO E;  1YJW E;  3CXC E;  5GAG G;  1YIT E;  5GAH G;  3CF5 E;  1VQO E;  3CCE E;  1Q7Y G;  2CQL A;  4WFN E;  4WFA E;  4WF9 E;  4UY8 G;  3CCR E;  1M90 G;  1YIJ E;  1VQ5 E;  2QA4 E;  1W2B E;  5H1S I;  2OTL E;  3CD6 E;  1QVF E;  3CCU E;  1VQN E;  5AN9 B;  3G4S E;  2ZJP E;  2ZJR E;  1VQ9 E;  3CC2 E;  3CCL E;  1K73 G;  4IOA E;  4WCE E;  1VQP E;  1VQK E;  3CME E;  3CCV E;  5DM7 E;  5GAD G;  5GAE G;  3CC7 E;  1Q81 G;  1M1K G;  3CMA E;  1JJ2 E;  5HL7 E;  1VQ7 E;  1VQ4 E;  3CCQ E;  3I56 E;  1KQS E;  1S72 E;  1RL6 A;  1VQM E;  3I55 E;  1Q86 G;  5MLC H;  3CCM E;  3OW2 E;  1K9M G;  4IO9 E;  3CC4 E;  3CCS E;  3CPW E;  1QVG E;  1NJI G;  2OTJ E;  4WFB E;  3G6E E;  4U67 E;  4IOC E;  1Q82 G;  1VQ8 E;  2ZJQ E;  5JVG E;  1YJN E;  1YJ9 E;  1YI2 E;  3CCJ E;  1K8A G;  5DM6 E;  3G71 E;  1VQL E;  1KD1 G;  3J7Z G;  1YHQ E;  3DLL E;  1VQ6 E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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