3G8VA

The rationally designed catalytically inactive mutant mth0212(d151n)
Total Genus 86
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
86
sequence length
255
structure length
255
Chain Sequence
AVLKIISWNVNGLRAVHRKGFLKWFMEEKPDILCLQEIKAAPEQLPRKLRHVEGYRSFFTPAERKGYSGVAMYTKVPPSSLREGFGVERFDTEGRIQIADFDDFLLYNIYFPNGKMSEERLKYKLEFYDAFLEDVNRERDSGRNVIICGNFNTAHREIDLARPKENSNVSGFLPVERAWIDKFIENGYVDTFRMFNSDPGQYTWWSYRTRARERNVGWRLDYFFVNEEFKGKVKRSWILSDVMGSDHCPIGLEIE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure Analysis of DNA Uridine Endonuclease Mth212 Bound to DNA
pubmed doi rcsb
molecule tags Hydrolase
source organism Methanothermobacter thermautotrophicus
molecule keywords Exodeoxyribonuclease
total genus 86
structure length 255
sequence length 255
ec nomenclature ec 3.1.11.2: Exodeoxyribonuclease III.
pdb deposition date 2009-02-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03372 Exo_endo_phos Endonuclease/Exonuclease/phosphatase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.10.10 Alpha Beta 4-Layer Sandwich Deoxyribonuclease I; Chain A Endonuclease/exonuclease/phosphatase 3g8vA00
2A3ZB 5CFGA 5HT2A 3G00A 1DE8A 4B5FA 1SR4B 4QH9A 2UYRX 5EWTA 4QHDA 3G3YA 2O3HA 1HD7A 1I9ZA 4B5HA 3I41A 5INLA 4L1YA 4FPVA 3G38A 5DV4A 3G2CA 5J3ZA 2D1KB 5A7JA 5J3PA 2A41B 4AWNA 3W3DB 4CMNA 5INMA 4IEMA 5INQA 2J63A 5CFEA 1ATND 4RUWA 5DG0A 3G1KA 1AKOA 1SI6X 3G91A 3CJCD 3G8VA 3I46A 4CMLA 5J42A 2EI9A 1NTFA 3GA6A 3K55A 3G3CA 3NGNA 1BIXA 3W2XA 2V0SA 2O3CA 2F2FB 3N9VA 1DE9A 4L20A 4PUQA 4JG3A 3G2DA 5INKA 3G6SA 3G4TA 3L1WA 2A40B 4GZ0A 3G0AA 3MTCA 1Y21A 5J8NA 4FVAA 2DDSA 4GZ1A 2JC4A 5INPA 4C1RA 2DDRA 3G0RA 3I48A 4L1ZA 5DV2A 4QHEA 2JC5A 3NR8A 3NGQA 5DFJA 5DFIA 5DFFA 1I9YA 3WCXA 5A7IA 2F1NA 2ISIA 4GEWA 4B5IA 2IMQX 4L21A 5DFHA 3DNIA 4LNDA 3MPRA 4F1HA 1DNKA 2A42B 2DDTA 3TEBA 4F1HB 1VYBA 1ZWXA 4F1IA 4F1RA 3NGOA 2XSWA 2DNJA 3W2YA 1YJHA 4B5GA 3I5VA 3FZIA 1DEWA 4K6LF 5J3SA 5INNA 4B5MA 1E9NA 2V0RA 4GYZA 4A9CA 4B5JA 3U8UA 4GZ2A 5INOA 2VOAA 1WDUA
chains in the Genus database with same CATH superfamily
2A3ZB 5CFGA 5HT2A 3G00A 1DE8A 4B5FA 1SR4B 4QH9A 2UYRX 5EWTA 4QHDA 3G3YA 2O3HA 1HD7A 1I9ZA 4B5HA 3I41A 5INLA 4L1YA 4FPVA 3G38A 5DV4A 3G2CA 5J3ZA 2D1KB 5A7JA 5J3PA 2A41B 4AWNA 3W3DB 4CMNA 5INMA 4IEMA 5INQA 2J63A 5CFEA 1ATND 4RUWA 5DG0A 3G1KA 1AKOA 1SI6X 3G91A 3CJCD 3G8VA 3I46A 4CMLA 5J42A 2EI9A 1NTFA 3GA6A 3K55A 3G3CA 3NGNA 1BIXA 3W2XA 2V0SA 2O3CA 2F2FB 3N9VA 1DE9A 4L20A 4PUQA 4JG3A 3G2DA 5INKA 3G6SA 3G4TA 3L1WA 2A40B 4GZ0A 3G0AA 3MTCA 1Y21A 5J8NA 4FVAA 2DDSA 4GZ1A 2JC4A 5INPA 4C1RA 2DDRA 3G0RA 3I48A 4L1ZA 5DV2A 4QHEA 2JC5A 3NR8A 3NGQA 5DFJA 5DFIA 5DFFA 1I9YA 3WCXA 5A7IA 2F1NA 2ISIA 4GEWA 4B5IA 2IMQX 4L21A 5DFHA 3DNIA 4LNDA 3MPRA 4F1HA 1DNKA 2A42B 2DDTA 3TEBA 4F1HB 1VYBA 1ZWXA 4F1IA 4F1RA 3NGOA 2XSWA 2DNJA 3W2YA 1YJHA 4B5GA 3I5VA 3FZIA 1DEWA 4K6LF 5J3SA 5INNA 4B5MA 1E9NA 2V0RA 4GYZA 4A9CA 4B5JA 3U8UA 4GZ2A 5INOA 2VOAA 1WDUA
chains in the Genus database with same CATH topology
2A3ZB 5CFGA 5HT2A 3G00A 1DE8A 4B5FA 1SR4B 4QH9A 2UYRX 5EWTA 4QHDA 3G3YA 2O3HA 1HD7A 1I9ZA 4B5HA 3I41A 5INLA 4L1YA 4FPVA 3G38A 5DV4A 3G2CA 5J3ZA 2D1KB 5A7JA 5J3PA 2A41B 4AWNA 3W3DB 4CMNA 5INMA 4IEMA 5INQA 2J63A 5CFEA 1ATND 4RUWA 5DG0A 3G1KA 1AKOA 1SI6X 3G91A 3CJCD 3G8VA 3I46A 4CMLA 5J42A 2EI9A 1NTFA 3GA6A 3K55A 3G3CA 3NGNA 1BIXA 3W2XA 2V0SA 2O3CA 2F2FB 3N9VA 1DE9A 4L20A 4PUQA 4JG3A 3G2DA 5INKA 3G6SA 3G4TA 3L1WA 2A40B 4GZ0A 3G0AA 3MTCA 1Y21A 5J8NA 4FVAA 2DDSA 4GZ1A 2JC4A 5INPA 4C1RA 2DDRA 3G0RA 3I48A 4L1ZA 5DV2A 4QHEA 2JC5A 3NR8A 3NGQA 5DFJA 5DFIA 5DFFA 1I9YA 3WCXA 5A7IA 2F1NA 2ISIA 4GEWA 4B5IA 2IMQX 4L21A 5DFHA 3DNIA 4LNDA 3MPRA 4F1HA 1DNKA 2A42B 2DDTA 3TEBA 4F1HB 1VYBA 1ZWXA 4F1IA 4F1RA 3NGOA 2XSWA 2DNJA 3W2YA 1YJHA 4B5GA 3I5VA 3FZIA 1DEWA 4K6LF 5J3SA 5INNA 4B5MA 1E9NA 2V0RA 4GYZA 4A9CA 4B5JA 3U8UA 4GZ2A 5INOA 2VOAA 1WDUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2A3Z B;  5CFG A;  5HT2 A;  3G00 A;  1DE8 A;  4B5F A;  1SR4 B;  4QH9 A;  2UYR X;  5EWT A;  4QHD A;  3G3Y A;  2O3H A;  1HD7 A;  1I9Z A;  4B5H A;  3I41 A;  5INL A;  4L1Y A;  4FPV A;  3G38 A;  5DV4 A;  3G2C A;  5J3Z A;  2D1K B;  5A7J A;  5J3P A;  2A41 B;  4AWN A;  3W3D B;  4CMN A;  5INM A;  4IEM A;  5INQ A;  2J63 A;  5CFE A;  1ATN D;  4RUW A;  5DG0 A;  3G1K A;  1AKO A;  1SI6 X;  3G91 A;  3CJC D;  3G8V A;  3I46 A;  4CML A;  5J42 A;  2EI9 A;  1NTF A;  3GA6 A;  3K55 A;  3G3C A;  3NGN A;  1BIX A;  3W2X A;  2V0S A;  2O3C A;  2F2F B;  3N9V A;  1DE9 A;  4L20 A;  4PUQ A;  4JG3 A;  3G2D A;  5INK A;  3G6S A;  3G4T A;  3L1W A;  2A40 B;  4GZ0 A;  3G0A A;  3MTC A;  1Y21 A;  5J8N A;  4FVA A;  2DDS A;  4GZ1 A;  2JC4 A;  5INP A;  4C1R A;  2DDR A;  3G0R A;  3I48 A;  4L1Z A;  5DV2 A;  4QHE A;  2JC5 A;  3NR8 A;  3NGQ A;  5DFJ A;  5DFI A;  5DFF A;  1I9Y A;  3WCX A;  5A7I A;  2F1N A;  2ISI A;  4GEW A;  4B5I A;  2IMQ X;  4L21 A;  5DFH A;  3DNI A;  4LND A;  3MPR A;  4F1H A;  1DNK A;  2A42 B;  2DDT A;  3TEB A;  4F1H B;  1VYB A;  1ZWX A;  4F1I A;  4F1R A;  3NGO A;  2XSW A;  2DNJ A;  3W2Y A;  1YJH A;  4B5G A;  3I5V A;  3FZI A;  1DEW A;  4K6L F;  5J3S A;  5INN A;  4B5M A;  1E9N A;  2V0R A;  4GYZ A;  4A9C A;  4B5J A;  3U8U A;  4GZ2 A;  5INO A;  2VOA A;  1WDU A; 
#chains in the Genus database with same CATH topology
 2A3Z B;  5CFG A;  5HT2 A;  3G00 A;  1DE8 A;  4B5F A;  1SR4 B;  4QH9 A;  2UYR X;  5EWT A;  4QHD A;  3G3Y A;  2O3H A;  1HD7 A;  1I9Z A;  4B5H A;  3I41 A;  5INL A;  4L1Y A;  4FPV A;  3G38 A;  5DV4 A;  3G2C A;  5J3Z A;  2D1K B;  5A7J A;  5J3P A;  2A41 B;  4AWN A;  3W3D B;  4CMN A;  5INM A;  4IEM A;  5INQ A;  2J63 A;  5CFE A;  1ATN D;  4RUW A;  5DG0 A;  3G1K A;  1AKO A;  1SI6 X;  3G91 A;  3CJC D;  3G8V A;  3I46 A;  4CML A;  5J42 A;  2EI9 A;  1NTF A;  3GA6 A;  3K55 A;  3G3C A;  3NGN A;  1BIX A;  3W2X A;  2V0S A;  2O3C A;  2F2F B;  3N9V A;  1DE9 A;  4L20 A;  4PUQ A;  4JG3 A;  3G2D A;  5INK A;  3G6S A;  3G4T A;  3L1W A;  2A40 B;  4GZ0 A;  3G0A A;  3MTC A;  1Y21 A;  5J8N A;  4FVA A;  2DDS A;  4GZ1 A;  2JC4 A;  5INP A;  4C1R A;  2DDR A;  3G0R A;  3I48 A;  4L1Z A;  5DV2 A;  4QHE A;  2JC5 A;  3NR8 A;  3NGQ A;  5DFJ A;  5DFI A;  5DFF A;  1I9Y A;  3WCX A;  5A7I A;  2F1N A;  2ISI A;  4GEW A;  4B5I A;  2IMQ X;  4L21 A;  5DFH A;  3DNI A;  4LND A;  3MPR A;  4F1H A;  1DNK A;  2A42 B;  2DDT A;  3TEB A;  4F1H B;  1VYB A;  1ZWX A;  4F1I A;  4F1R A;  3NGO A;  2XSW A;  2DNJ A;  3W2Y A;  1YJH A;  4B5G A;  3I5V A;  3FZI A;  1DEW A;  4K6L F;  5J3S A;  5INN A;  4B5M A;  1E9N A;  2V0R A;  4GYZ A;  4A9C A;  4B5J A;  3U8U A;  4GZ2 A;  5INO A;  2VOA A;  1WDU A; 
#chains in the Genus database with same CATH homology
 2A3Z B;  5CFG A;  5HT2 A;  3G00 A;  1DE8 A;  4B5F A;  1SR4 B;  4QH9 A;  2UYR X;  5EWT A;  4QHD A;  3G3Y A;  2O3H A;  1HD7 A;  1I9Z A;  4B5H A;  3I41 A;  5INL A;  4L1Y A;  4FPV A;  3G38 A;  5DV4 A;  3G2C A;  5J3Z A;  2D1K B;  5A7J A;  5J3P A;  2A41 B;  4AWN A;  3W3D B;  4CMN A;  5INM A;  4IEM A;  5INQ A;  2J63 A;  5CFE A;  1ATN D;  4RUW A;  5DG0 A;  3G1K A;  1AKO A;  1SI6 X;  3G91 A;  3CJC D;  3G8V A;  3I46 A;  4CML A;  5J42 A;  2EI9 A;  1NTF A;  3GA6 A;  3K55 A;  3G3C A;  3NGN A;  1BIX A;  3W2X A;  2V0S A;  2O3C A;  2F2F B;  3N9V A;  1DE9 A;  4L20 A;  4PUQ A;  4JG3 A;  3G2D A;  5INK A;  3G6S A;  3G4T A;  3L1W A;  2A40 B;  4GZ0 A;  3G0A A;  3MTC A;  1Y21 A;  5J8N A;  4FVA A;  2DDS A;  4GZ1 A;  2JC4 A;  5INP A;  4C1R A;  2DDR A;  3G0R A;  3I48 A;  4L1Z A;  5DV2 A;  4QHE A;  2JC5 A;  3NR8 A;  3NGQ A;  5DFJ A;  5DFI A;  5DFF A;  1I9Y A;  3WCX A;  5A7I A;  2F1N A;  2ISI A;  4GEW A;  4B5I A;  2IMQ X;  4L21 A;  5DFH A;  3DNI A;  4LND A;  3MPR A;  4F1H A;  1DNK A;  2A42 B;  2DDT A;  3TEB A;  4F1H B;  1VYB A;  1ZWX A;  4F1I A;  4F1R A;  3NGO A;  2XSW A;  2DNJ A;  3W2Y A;  1YJH A;  4B5G A;  3I5V A;  3FZI A;  1DEW A;  4K6L F;  5J3S A;  5INN A;  4B5M A;  1E9N A;  2V0R A;  4GYZ A;  4A9C A;  4B5J A;  3U8U A;  4GZ2 A;  5INO A;  2VOA A;  1WDU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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