3GBRA

Anthranilate phosphoribosyl-transferase (trpd) double mutant d83g f149s from s. solfataricus
Total Genus 123
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
123
sequence length
344
structure length
341
Chain Sequence
MNINEILKKLINKSDLEINEAEELAKAIIRGEVPEILVSAILVALRMKGESKNEIVGFARAMRELAIKIDVPNAIDTAGTGGGGLGTVNVSTASAILLSLVNPVAKHGNRAKSGSADVLEALGYNIIVPPERAKELVNKTNFVFLSAQYYHPAMKNVANVRKTLGIRTIFNILGPLTNPANAKYQLMGVFSKDHLDLLSKSAYELDFNKIILVYGEPGIDEVSPIGNTFMKIVSKRGIEEVKLNVTDFGISPIPIEKLIVNSAEDSAIKIVRAFLGKDEHVAEFIKINTAVALFALDRVGDFREGYEYADHLIEKSLDKLNEIISMNGDVTKLKTIVVKSS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Activation of anthranilate phosphoribosyltransferase from Sulfolobus solfataricus by removal of magnesium inhibition and acceleration of product release
pubmed doi rcsb
molecule tags Transferase
source organism Sulfolobus solfataricus
molecule keywords Anthranilate phosphoribosyltransferase
total genus 123
structure length 341
sequence length 344
chains with identical sequence B
ec nomenclature ec 2.4.2.18: Anthranilate phosphoribosyltransferase.
pdb deposition date 2009-02-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00591 Glycos_transf_3 Glycosyl transferase family, a/b domain
A PF02885 Glycos_trans_3N Glycosyl transferase family, helical bundle domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.970.10 Mainly Alpha Up-down Bundle Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C 3gbrA01
3.40.1030.10 Alpha Beta 3-Layer(aba) Sandwich Pyrimidine Nucleoside Phosphorylase; Chain A, domain 2 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 3gbrA02
5BO2A 4OWOA 1BRWA 4GA4A 3QR9A 1VQUA 2ELCA 4OWMA 5EP8A 5C7SA 3H5QA 3TWPA 1KHDA 4GKMA 4X59A 5EY3A 4OWQA 4YEKA 3R88A 1UOUA 4HKMA 4M0RA 3GBRA 2TPTA 4YI7A 1ZXYA 4OWVA 2GVQA 4GIUA 1ZYKA 4OWSA 2J0FA 1KGZA 4IJ1A 5BYTA 1AZYA 2BPQA 5C2LA 4X5CA 4MUOA 4X5EA 4XR5A 4GA5A 4N93A 2WK5A 3R6CA 4EADA 3QS8A 4X58A 4N8QA 1GXBA 4X5AA 1V8GA 4ZTVA 4N5VA 4ZOFA 4ZOKA 5C1RA 4X5BA 2DSJA 1O17A 4LHMA 4X46A 1ZVWA 5BNEA 4X5DA 4ZOJA 1OTPA 4OWUA 3UU1A 4GTNA 2WK6A 4EAFA 3QSAA 4GA6A 5BO3A 4YYYA 3QQSA 4OWNA
chains in the Genus database with same CATH superfamily
5BO2A 4OWOA 1RF8B 1BRWA 4GA4A 3QR9A 1VQUA 2ELCA 4OWMA 5EP8A 5C7SA 3H5QA 3TWPA 1KHDA 4GKMA 4X59A 5EY3A 4OWQA 4YEKA 3R88A 1UOUA 4HKMA 4M0RA 3GBRA 2TPTA 4YI7A 1ZXYA 4OWVA 2GVQA 4GIUA 1ZYKA 4OWSA 2J0FA 1KGZA 4IJ1A 5BYTA 1AZYA 2BPQA 5C2LA 4X5CA 4MUOA 4X5EA 4XR5A 4GA5A 4N93A 1RRZA 2WK5A 3R6CA 4EADA 3QS8A 4F3FC 4X58A 4N8QA 1GXBA 4X5AA 1V8GA 4ZTVA 4N5VA 4ZOFA 4ZOKA 5C1RA 4X5BA 2DSJA 1O17A 4LHMA 4X46A 1ZVWA 5BNEA 4X5DA 4ZOJA 1OTPA 4OWUA 3UU1A 4GTNA 2WK6A 4EAFA 3QSAA 4GA6A 5BO3A 4YYYA 3QQSA 4OWNA
chains in the Genus database with same CATH topology
5BO2A 4OWOA 1BRWA 4GA4A 3QR9A 1VQUA 2ELCA 4OWMA 5EP8A 5C7SA 3H5QA 3TWPA 1KHDA 4GKMA 4X59A 5EY3A 4OWQA 4YEKA 3R88A 1UOUA 4HKMA 4M0RA 3GBRA 2TPTA 4YI7A 1ZXYA 4OWVA 2GVQA 4GIUA 1ZYKA 4OWSA 2J0FA 1KGZA 4IJ1A 5BYTA 1AZYA 2BPQA 5C2LA 4X5CA 4MUOA 4X5EA 4XR5A 4GA5A 4N93A 2WK5A 3R6CA 4EADA 3QS8A 4X58A 4N8QA 1GXBA 4X5AA 1V8GA 4ZTVA 4N5VA 4ZOFA 4ZOKA 5C1RA 4X5BA 2DSJA 1O17A 4LHMA 4X46A 1ZVWA 5BNEA 4X5DA 4ZOJA 1OTPA 4OWUA 3UU1A 4GTNA 2WK6A 4EAFA 3QSAA 4GA6A 5BO3A 4YYYA 3QQSA 4OWNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5BO2 A;  4OWO A;  1BRW A;  4GA4 A;  3QR9 A;  1VQU A;  2ELC A;  4OWM A;  5EP8 A;  5C7S A;  3H5Q A;  3TWP A;  1KHD A;  4GKM A;  4X59 A;  5EY3 A;  4OWQ A;  4YEK A;  3R88 A;  1UOU A;  4HKM A;  4M0R A;  3GBR A;  2TPT A;  4YI7 A;  1ZXY A;  4OWV A;  2GVQ A;  4GIU A;  1ZYK A;  4OWS A;  2J0F A;  1KGZ A;  4IJ1 A;  5BYT A;  1AZY A;  2BPQ A;  5C2L A;  4X5C A;  4MUO A;  4X5E A;  4XR5 A;  4GA5 A;  4N93 A;  2WK5 A;  3R6C A;  4EAD A;  3QS8 A;  4X58 A;  4N8Q A;  1GXB A;  4X5A A;  1V8G A;  4ZTV A;  4N5V A;  4ZOF A;  4ZOK A;  5C1R A;  4X5B A;  2DSJ A;  1O17 A;  4LHM A;  4X46 A;  1ZVW A;  5BNE A;  4X5D A;  4ZOJ A;  1OTP A;  4OWU A;  3UU1 A;  4GTN A;  2WK6 A;  4EAF A;  3QSA A;  4GA6 A;  5BO3 A;  4YYY A;  3QQS A;  4OWN A; 
#chains in the Genus database with same CATH topology
 5BO2 A;  4OWO A;  1RF8 B;  1BRW A;  4GA4 A;  3QR9 A;  1VQU A;  2ELC A;  4OWM A;  5EP8 A;  5C7S A;  3H5Q A;  3TWP A;  1KHD A;  4GKM A;  4X59 A;  5EY3 A;  4OWQ A;  4YEK A;  3R88 A;  1UOU A;  4HKM A;  4M0R A;  3GBR A;  2TPT A;  4YI7 A;  1ZXY A;  4OWV A;  2GVQ A;  4GIU A;  1ZYK A;  4OWS A;  2J0F A;  1KGZ A;  4IJ1 A;  5BYT A;  1AZY A;  2BPQ A;  5C2L A;  4X5C A;  4MUO A;  4X5E A;  4XR5 A;  4GA5 A;  4N93 A;  1RRZ A;  2WK5 A;  3R6C A;  4EAD A;  3QS8 A;  4F3F C;  4X58 A;  4N8Q A;  1GXB A;  4X5A A;  1V8G A;  4ZTV A;  4N5V A;  4ZOF A;  4ZOK A;  5C1R A;  4X5B A;  2DSJ A;  1O17 A;  4LHM A;  4X46 A;  1ZVW A;  5BNE A;  4X5D A;  4ZOJ A;  1OTP A;  4OWU A;  3UU1 A;  4GTN A;  2WK6 A;  4EAF A;  3QSA A;  4GA6 A;  5BO3 A;  4YYY A;  3QQS A;  4OWN A; 
#chains in the Genus database with same CATH homology
 5BO2 A;  4OWO A;  1BRW A;  4GA4 A;  3QR9 A;  1VQU A;  2ELC A;  4OWM A;  5EP8 A;  5C7S A;  3H5Q A;  3TWP A;  1KHD A;  4GKM A;  4X59 A;  5EY3 A;  4OWQ A;  4YEK A;  3R88 A;  1UOU A;  4HKM A;  4M0R A;  3GBR A;  2TPT A;  4YI7 A;  1ZXY A;  4OWV A;  2GVQ A;  4GIU A;  1ZYK A;  4OWS A;  2J0F A;  1KGZ A;  4IJ1 A;  5BYT A;  1AZY A;  2BPQ A;  5C2L A;  4X5C A;  4MUO A;  4X5E A;  4XR5 A;  4GA5 A;  4N93 A;  2WK5 A;  3R6C A;  4EAD A;  3QS8 A;  4X58 A;  4N8Q A;  1GXB A;  4X5A A;  1V8G A;  4ZTV A;  4N5V A;  4ZOF A;  4ZOK A;  5C1R A;  4X5B A;  2DSJ A;  1O17 A;  4LHM A;  4X46 A;  1ZVW A;  5BNE A;  4X5D A;  4ZOJ A;  1OTP A;  4OWU A;  3UU1 A;  4GTN A;  2WK6 A;  4EAF A;  3QSA A;  4GA6 A;  5BO3 A;  4YYY A;  3QQS A;  4OWN A; 
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similar chains in the Genus database (?% sequence similarity)
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